• • DRAMP ID

  • DRAMP00929

• • Peptide Name

  • Antimicrobial peptide 1 (Cn-AMP1; Plant defensin)

• • Source

  • Cocos nucifera (Coconut palm)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • SVAGRAQGM

• • Sequence Length

  • 9

• • UniProt Entry

  • P86705

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • [Ref.19111587] Gram-positive bacteria: Bacillus subtilis (MIC=76 μg/ml), Staphylococcus aureus (MIC=80 μg/ml);
    • Gram-negative bacteria: Escherichia coli (MIC=82 μg/ml), Pseudomonas aeruginosa (MIC=79 μg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Helix

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • 2N0V resolved by NMR.

• Predicted Structure

• There is no predicted structure for DRAMP00929.

DRAMP00929

• • Function

  • Antibacterial activity against Gram-negative and Gram-positive bacteria.

• • Tissue specificity

  • Found in the liquid endosperm contained in green fruit of coconut palms, also known as coconut water (at protein level).

• • Subunit structure

  • Monomer.

• ·Literature 1

• • Title

  • Identification and structural insights of three novel antimicrobial peptides isolated from green coconut water.

• • Pubmed ID

  • 19111587

• • Reference

  • Peptides. 2009 Apr;30(4):633-637.

• • Author

  • Mandal SM, Dey S, Mandal M, Sarkar S, Maria-Neto S, Franco OL.