• • DRAMP ID

  • DRAMP01022

• • Peptide Name

  • Cy-AMP1 (Plant defensin)

• • Source

  • Cycas revoluta (cycad seeds)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • KGAPCAKKPCCGPLGHYKVDCSTIPDYPCCSKYGFCGSGPQYCG

• • Sequence Length

  • 44

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-positive bacteria: Clavibacterium michiganensis (IC50=7.3 µg/ml), Curtobacterium flaccumfaciens (IC50=8.9 µg/ml);
    • Gram-negative bacteria: Agrobacterium radiobacter (IC50=8.3 µg/ml), Agrobacterium rhizogenes (IC50=8.5 µg/ml), Erwinia carobora (IC50=8.0 µg/ml).
    • Fungi: Fusarium oxysporum (IC50=6.0 µg/ml), Geotrichum candidum (IC50=7.4 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Lipid-binding

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP01022.

DRAMP01022

• • Function

  • Cy-AMP1 has antimicrobial activity against various plant-pathogenic fungi and bacteria.

• ·Literature 1

• • Title

  • Purification, characterization, and sequencing of antimicrobial peptides, Cy-AMP1, Cy-AMP2, and Cy-AMP3, from the Cycad (Cycas revoluta) seeds.

• • Pubmed ID

  • 18778743

• • Reference

  • Peptides. 2008 Dec;29(12):2110-2117.

• • Author

  • Yokoyama S, Kato K, Koba A, Minami Y, Watanabe K, Yagi F.