• DRAMP ID

    • DRAMP01184
    • Peptide Name

    • SPX(1-22)(truncated peptide of Syphaxin; Frogs, amphibians, animals)
    • Source

    • Leptodactylus syphax (Burgundy thin-toed frog)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • GVLDILKGAAKDLAGHVATKVI
    • Sequence Length

    • 22
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus ATCC 29213 (MIC=14.6 µM);
      • Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=40.5 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Free
    • Nonterminal Modifications and Unusual Amino Acids

    • Free
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01184 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01184.
    • Formula

    • C99H173N27O28
    • Absent Amino Acids

    • CEFMNPQRSWY
    • Common Amino Acids

    • A
    • Mass

    • 2189.63
    • PI

    • 8.51
    • Basic Residues

    • 4
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +2
    • Boman Index

    • 5.46
    • Hydrophobicity

    • 0.746
    • Aliphatic Index

    • 146.36
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 4

DRAMP01184

DRAMP01184 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Antimicrobial peptide from the skin secretion of the frog Leptodactylus syphax.
    • Reference

    • Toxicon. 2007 Sep 15;50(4):572-580.
    • Author

    • Dourado F.S, Leite J.R.S.A, Silva L.P, Melo J.A.T, Bloch C. Jr, Schwartz E.F.