• DRAMP ID

    • DRAMP02344
    • Peptide Name

    • 40S ribosomal protein S30 (Fish, chordates, animals)
    • Source

    • Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
    • Family

    • Belongs to the eukaryotic ribosomal protein eS30 family.
    • Gene

    • fau
    • Sequence

    • KVHGSLARAGK
    • Sequence Length

    • 11
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • [Ref.12147245] Gram-negetive bacteria: Escherichia coli (EC50>0.3 μM, MBC>0.3 μM), Listonella anguillarum (EC50>0.3 μM, MBC>0.3 μM) ;
      • Gram-positive bacteria: Bacillus subtilis (EC50=0.15–0.3 μM, MBC>0.3 μM), Planococcus citreus (EC50=0.02–0.04 μM, MBC=0.08 μM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Free
    • Nonterminal Modifications and Unusual Amino Acids

    • Free
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02344 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02344.
    • Formula

    • C48H86N18O13
    • Absent Amino Acids

    • CDEFIMNPQTWY
    • Common Amino Acids

    • AGK
    • Mass

    • 1123.32
    • PI

    • 11.17
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 4
    • Net Charge

    • +4
    • Boman Index

    • -19.62
    • Hydrophobicity

    • -0.5
    • Aliphatic Index

    • 80
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 3

DRAMP02344

    • Function

    • Antibacterial activity against Gram-positive bacteria and low activity against Gram-negative bacteria.
  • ·Literature 1
    • Title

    • A novel antimicrobial function for a ribosomal peptide from rainbow trout skin.
    • Reference

    • Biochem Biophys Res Commun. 2002 Aug 9;296(1):167-171.
    • Author

    • Fernandes JM, Smith VJ.