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Sequence
- XCRRLCYKQRCVTYCRAR
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Sequence Name
- Sequence 43 from Patent US 20030186854
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Activity
- Antimicrobial, Antiparasitic, Antifungal
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Patent Type
- Patent Application
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Publication Date
- 2003-10-2
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Patent Title
- Antimicrobial peptide, process to obtain a peptide and uses therefor.
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Abstract
- The invention refers to small peptides with low hemolytic activity, presenting equal antiparasitic, antifungal and antibacterial activities. More specifically, it refers to a peptide called gomesin, with 18 amino acid residues, configured as a clamp-like structure consisting of two anti-parallel beta-folded sheets joined by a beta turn, containing four invariable residues of cystein forming two disulphide bridges, optionally configurable as a cyclic chain with closed edges.