Sequence Information

    • DRAMP ID

    • DRAMP18076

    • Name

    • HB-107

    • Sequence

    • MPKEKVFLKIEKMGRNIRN

    • Description

    • 19-amino-acid fragment of cecropin B

    • Activity

    • Unknown

    • Target Organism

      • No MICs found on DRAMP database

    • Reference

      • HB-107, a nonbacteriostatic fragment of the antimicrobial peptide cecropin B, accelerates murine wound repair.WOUND REPAIR AND REGENERATION.2004 MAY-JUN.(PMID: 15225214)

Clinical Information

    • Medical use

    • Wound healing

    • Company

    • Helix Biomedix(Bothell, Washington, USA)

    • Stage of Development

    • Preclinical

    • Comments

    • Wounds treated with HB-107 showed keratinocyte hyperplasia and increased leukocyte infiltration. Furthermore, HB-107 stimulated interleukin-8 secretion from cultured endothelial cells.

    • Clinical Trials