General Information
-
DRAMP ID
- DRAMP18419
-
Peptide Name
- STiDA-2
-
Source
- Deduced; synthetic
-
Family
- Belongs to the defensin family.
-
Gene
- Not found
-
Sequence
- GGFGCPFNIDNQGNCHNHCQSIRGRKGGYCHGIPKQTCKCYKPMGYKARPPFILG
-
Sequence Length
- 55
-
UniProt Entry
- No entry found
-
Protein Existence
Activity Information
-
Biological Activity
- Antiparasitic
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Bridge
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18419.
Physicochemical Information
-
Formula
- C263H400N82O69S7
Absent Amino Acids
- EVW
Common Amino Acids
- G
Mass
- 6057.01
PI
- 9.42
Basic Residues
- 11
Acidic Residues
- 1
Hydrophobic Residues
- 9
Net Charge
- +10
-
Boman Index
- -9000
Hydrophobicity
- -0.698
Aliphatic Index
- 36.61
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 4845
Absorbance 280nm
- 88.09
Polar Residues
- 25
DRAMP18419
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Antiplasmodial Activity Is an Ancient and Conserved Feature of Tick Defensins.
-
Pubmed ID
- 27822206
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Reference
- Front Microbiol. 2016 Oct 24;7:1682
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Author
- Cabezas-Cruz A, Tonk M, Bouchut A, Pierrot C, Pierce RJ, Kotsyfakis M, Rahnamaeian M, Vilcinskas A, Khalife J, Vald