General Information

    • DRAMP ID

    • DRAMP18455

    • Peptide Name

    • Tomato Snakin-2 (plants)

    • Source

    • Solanum lycopersicum

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • DSYKKIDCGGACAARCRLSSRPRLCHRACGTCCARCNCVPPGTSGNTETCPCYASLTTHGNKRKCP

    • Sequence Length

    • 66

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Target Organism

    • Active against E. coli, B. subtilis, and S. cerevisiae.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18455 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18455.

Physicochemical Information

    • Formula

    • C280H464N98O89S12

    • Absent Amino Acids

    • FMQW

    • Common Amino Acids

    • C

    • Mass

    • 7012.09

    • PI

    • 9.06

    • Basic Residues

    • 13

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +10

    • Boman Index

    • -15725

    • Hydrophobicity

    • -0.527

    • Aliphatic Index

    • 37.12

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 3730

    • Absorbance 280nm

    • 57.38

    • Polar Residues

    • 34

DRAMP18455

DRAMP18455 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Over-expression of snakin-2 and extensin-like protein genes restricts pathogen invasiveness and enhances tolerance to Clavibacter michiganensis subsp. michiganensis in transgenic tomato (Solanum lycopersicum).

    • Reference

    • Transgenic Res. 2012 Feb;21(1):23-37.

    • Author

    • Balaji V, Smart CD.
  • ·Literature 2

    • Title

    • Mode of action and membrane specificity of the antimicrobial peptide snakin-2.

    • Reference

    • PeerJ. 2016 May 10;4:e1987.

    • Author

    • Herbel V, Wink M.