• DRAMP ID

    • DRAMP18456
    • Peptide Name

    • Pepcon (peptide consensus sequence, synthetic)
    • Source

    • Designed based on sequence alignment with scorpion linear peptides
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • FSLIPSAIGGLISA
    • Sequence Length

    • 18
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-positive bacteria: S. epidermidis ATCC 12228 (MIC 7.5 uM),S. aureus (5 uM);
      • Gram-negative bacteria: E. coli ATCC 25922 (MIC 50 uM), S. enterica ATCC 10708 (60 uM), P. aeruginosa ATCC 27853 (40uM), A. baumannii ATCC 19606 (MIC 20 uM),K. pneumoniae (60 uM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP18456 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP18456.
    • Formula

    • C63H104N14O18
    • Absent Amino Acids

    • CDEHKMNQRTVWY
    • Common Amino Acids

    • IS
    • Mass

    • 1345.6
    • PI

    • 5.52
    • Basic Residues

    • 0
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 8
    • Net Charge

    • 0
    • Boman Index

    • 2288
    • Hydrophobicity

    • 1.621
    • Aliphatic Index

    • 153.57
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 5

DRAMP18456

DRAMP18456 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Peptide consensus sequence determination for the enhancement of the antimicrobial activity and selectivity of antimicrobial peptides.
    • Reference

    • Infect Drug Resist. 2016 Dec 29;10:1-17.
    • Author

    • Almaaytah A, Ajingi Y, Abualhaijaa A, Tarazi S, Alshar'i N, Al-Balas Q