General Information

    • DRAMP ID

    • DRAMP18492

    • Peptide Name

    • cgUbiquitin (Oyster, mollusca/molluscs/mollusks, invertebrates, animals)

    • Source

    • Pacific oyster(Crassostrea gigas)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR

    • Sequence Length

    • 74

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+

    • Target Organism

      • Gram-positive bacteria: Bacillus subtilis KCTC1021 (MIC=0.4

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Helix and Beta

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18492 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18492.

Physicochemical Information

    • Formula

    • C374H623N103O116S

    • Absent Amino Acids

    • CW

    • Common Amino Acids

    • L

    • Mass

    • 8450.74

    • PI

    • 6.56

    • Basic Residues

    • 12

    • Acidic Residues

    • 11

    • Hydrophobic Residues

    • 24

    • Net Charge

    • +1

    • Boman Index

    • -15193

    • Hydrophobicity

    • -0.492

    • Aliphatic Index

    • 102.7

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 20.41

    • Polar Residues

    • 17

DRAMP18492

DRAMP18492 chydropathy plot

Comments Information

    • Function

    • Antimicrobial activity against Gram-positive, Gram-negative bacteria and Yeast.

Literature Information

  • ·Literature 1

    • Title

    • Purification and antimicrobial function of ubiquitin isolated from the gill of Pacific oyster, Crassostrea gigas.

    • Reference

    • Mol Immunol. 2013 Jan;53(1-2):88-98.

    • Author

    • Seo JK, Lee MJ, Go HJ, Kim GD, Jeong HD, Nam BH, Park NG.