General Information

    • DRAMP ID

    • DRAMP18709

    • Peptide Name

    • Mastoparan (MP; insects, arthropods, invertebrates, animals)

    • Source

    • Vespula flaviceps lewisii (Korean yellow-jacket isp)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • INLKALAALAKKIL

    • Sequence Length

    • 14

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Cell degranulating

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Helix

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18709 helical wheel diagram

    • PDB ID

    • 1D7N resolved by NMR

    • Predicted Structure

    • There is no predicted structure for DRAMP18709.

Physicochemical Information

    • Formula

    • C70H130N18O16

    • Absent Amino Acids

    • CDEFGHMPQRSTVWY

    • Common Amino Acids

    • AL

    • Mass

    • 1479.91

    • PI

    • 10.3

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +3

    • Boman Index

    • 1347

    • Hydrophobicity

    • 1.157

    • Aliphatic Index

    • 195.71

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 1

DRAMP18709

Comments Information

    • Function

    • Antibacterial and cell degranulating activity.

Literature Information

  • ·Literature 1

    • Title

    • A new mast cell degranulating peptide mastoparan in the venom of Vespula lewisii

    • Reference

    • Chem Pharm Bull (Tokyo). 1979 Aug;27(8):1942-4

    • Author

    • Hirai Y, Yasuhara T, Yoshida H, Nakajima T, Fujino M, Kitada C.