• DRAMP ID

    • DRAMP18711
    • Peptide Name

    • Chicken Heterophil Peptide 2 (CHP-2, avian beta-defensin, birds, animals)
    • Source

    • Gallus gallus (Chicken)
    • Family

    • Belongs to the beta-defensin family.
    • Gene

    • Not found
    • Sequence

    • GRKSDCFRKNGFCAFLKCPYLTLISGLCSFHLC
    • Sequence Length

    • 33
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Bridge
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP18711 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP18711.
    • Formula

    • C167H259N45O42S5
    • Absent Amino Acids

    • EMQVW
    • Common Amino Acids

    • CL
    • Mass

    • 3729.47
    • PI

    • 9.04
    • Basic Residues

    • 6
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 11
    • Net Charge

    • +5
    • Boman Index

    • -2695
    • Hydrophobicity

    • 0.33
    • Aliphatic Index

    • 73.94
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1740
    • Absorbance 280nm

    • 54.38
    • Polar Residues

    • 14

DRAMP18711

DRAMP18711 chydropathy plot
    • Function

    • Has bactericidal activity. Potent activity against E.coli ML-35, L.monocytogenes EGD and C.albicans.
  • ·Literature 1
    • Title

    • Isolation of antimicrobial peptides from avian heterophils.
    • Reference

    • J. Leukoc. Biol. 1994; 56: 661-665.
    • Author

    • Evans EW, Beach GG, Wunderlich J, Harmon BG.