• DRAMP ID

    • DRAMP18723
    • Peptide Name

    • CE (Cecropin A (1
    • Source

    • Hyalophora cecropia (Cecropia moth)
    • Family

    • Belongs to truncated Cecropin A.
    • Gene

    • Not found
    • Sequence

    • KWKLFKKI
    • Sequence Length

    • 8
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-
    • Target Organism

      • [Ref.28178190] Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=64 μM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • random coil
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP18723 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP18723.
    • Formula

    • C56H91N13O9
    • Absent Amino Acids

    • ACDEGHMNPQRSTVY
    • Common Amino Acids

    • K
    • Mass

    • 1090.42
    • PI

    • 10.48
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 4
    • Net Charge

    • +4
    • Boman Index

    • -705
    • Hydrophobicity

    • -0.675
    • Aliphatic Index

    • 97.5
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 5500
    • Absorbance 280nm

    • 785.71
    • Polar Residues

    • 0

DRAMP18723

    • Function

    • Antibacterial activity against the Gram-negative bacteria and Gram-positive bacteria.
  • ·Literature 1
    • Title

    • High Specific Selectivity and Membrane-Active Mechanism of Synthetic Cationic Hybrid Antimicrobial Peptides Based on the Peptide FV7
    • Reference

    • Int J Mol Sci. 2017 Feb 6;18(2). pii: E339.
    • Author

    • Tan T, Wu D, Li W, Zheng X, Li W, Shan A.