DRAMP_ID	Sequence	Sequence_Length	Name	Swiss_Prot_Entry	Family	Gene	Source	Activity	Protein_existence	Structure	Structure_Description	PDB_ID	Comments	Target_Organism	Hemolytic_activity	Linear/Cyclic/Branched	N-terminal_Modification	C-terminal_Modification	Other_Modifications	Stereochemistry	Cytotoxicity	Binding_Traget	Pubmed_ID	Reference	Author	Title
DRAMP00275	GSSFCDSKCKLRCSKAGLADRCLKYCGICCEECKCVPSGTYGNKHECPCYRDKKNSKGKSKCP	63	Snakin-1 (StSN1; Cys-rich; Plant defensin)	Q948Z4	Not found	SN1	Solanum tuberosum (potato)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: Has an antimicrobial activity. Causes a rapid aggregation of both Gram-positive and Gram-negative bacteria, but the antimicrobial activity is not correlated with the capacity to aggregate bacteria.
Tissue specificity: Expressed in tubers, stems, axillary and young floral buds, sepals, petals, stamens and carpels, but not in roots, stolons, shoot apex meristem or young leaves.
Induction: No responses to methyl jasmonate, ethylene, abscisic acid, salicylic acid, isonicotinic acid, indolacetic acid, gibberellic acid and infection with incompatible bacterial or compatible fungual pathogens.
PTM: Six disulfide bonds may be present."	"[Ref.9885189] Gram-positive bacteria: Listeria monocytogenes (MIC=10 ?g/mL), Listeria innocua (MIC=10 ?g/mL), Listeria ivanovii (MIC=10 ?g/mL), Clavibacter michiganensis (EC50=1 ?M), Ralstonia solanacearum (rfa-) (EC50=30 ?M), Rhizobium meliloti (EC50=8 ?M).##Fungi: Botrytis cinerea (EC50=2 ?M), Fusarium solani (EC50=3 ?M), Fusarium culmorum (EC50=2 ?M), Fusarium oxysporum f. sp. conglutinans (EC50=10 ?M), Fusarium oxysporum f. sp. lycopersici (EC50=20 ?M), Plectosphaerella cucumerina (EC50=10 ?M), Colletotrichum graminicola (EC50=10 ?M), Colletotrichum lagenarium (EC50=10 ?M), Bipolaris maydis (EC50=20 ?M), Aspergillus flavus (EC50=20 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	[Ref.9885189] Six disulfide bonds may be present	L	No cytotoxicity information found	Not found	11891250##9885189	Plant Physiol. 2002 Mar;128(3):951-961.##Mol Plant Microbe Interact. 1999 Jan;12(1):16-23.	"Marta Berrocal-Lobo, Ana Segura, Manuel Moreno, Gemma L¨®pez, Francisco Garc¨ªa-Olmedo, Antonio Molina##A Segura, M Moreno, F Madue?o, A Molina, F Garc¨ªa-Olmedo"	"Snakin-2, an antimicrobial peptide from potato whose gene is locally induced by wounding and responds to pathogen infection.##Snakin-1, a peptide from potato that is active against plant pathogens."
DRAMP00384	GNEGGGHGGHGGYGGYHHHGGGGGGYGGYHGGGGS	35	Cc-GRP (Gly-rich; Plants)	No entry found	Not found	Not found	Coffea canephora	"Antimicrobial, Antifungal"	Not found	Rich	Not found	None	"Comment: The sequence displayed is only the N-terminal sequence of 7 kD peptide. The peptide was located in the cell wall, cell surface and nucleus of Fusarium oxysporum. "	"Fungi: Candida albicans (MIC=90 ?g/ml), Candida tropicalis (MIC=180 ?g/ml), Colletotrichum lindemuthianum (MIC=90 ?g/ml), Fusarium oxysporium (MIC=90 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	None	L	No cytotoxicity information found	Not found	23500079	Biochim Biophys Acta. 2013 Mar 15.[Epub ahead of print]	"Zottich U, Da Cunha M, Carvalho AO, Dias GB, Casarin N, Vasconcelos IM, Gomes VM."	An antifungal peptide from Coffea canephora seeds with sequence homology to glycine-rich proteins exerts membrane permeabilization and nuclear localization in fungi.
DRAMP00416	KLCERSSGTWSGVCGNNNACKNQCIRLEGAQHGSCNYVFPAHKCICYFPC	50	Raphanus sativus Antifungal Protein 3 (Rs-AFP3; Plant defensin)	"O24332, Q39313"	Belongs to the DEFL family	AFP3	Raphanus sativus (Radish) & Brassica napus (Rape)	"Antimicrobial, Antifungal"	Protein inferred from homology	Bridge	Not found	None	"Function: Possesses antifungal activity sensitive to inorganic cations (By similarity).
PTM: Problely contains four disulfide bonds 3-50; 14-35; 20-44; 24-46."	"Fungi: Alternaria brassicicola (MIC=2 ?g/ml), Botrytis cinerea (MIC=2 ?g/ml), Fusarium culmorum (MIC=2 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"There are four disulfide bonds between Cys3 and Cys50, Cys14 and Cys35, Cys20 and Cys44, Cys24 and Cys51."	L	No cytotoxicity information found	Not found	7780308##8422949	Plant Cell. 1995 May;7(5):573-588.##FEBS Lett. 1993 Feb 1;316(3):233-240.	"Terras FR, Eggermont K, Kovaleva V, Raikhel NV, Osborn RW, Kester A, Rees SB, Torrekens S, Van Leuven F, Vanderleyden J, et al.##Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF."	Small cysteine-rich antifungal proteins from radish: their role in host defense.##A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
DRAMP00417	QKLCERSSGTWSGVCGNNNACKNQCINLEGARHGSCNYIFPYHRCICYFPC	51	Raphanus sativus Antifungal Protein 4 (Rs-AFP4; Plant defensin)	O24331	Belongs to the DEFL family	AFP4	Raphanus sativus (Radish)	"Antimicrobial, Antifungal"	Protein inferred from homology	Bridge	Not found	None	"PTM: Contains four disulfide bonds 4-51;15-36;21-45;25-47, and Pyrrolidone carboxylic acid at position 1."	"Fungi: Alternaria brassicicola (MIC=5 ?g/ml), Botrytis cinerea (MIC=9 ?g/ml), Fusarium culmorum (MIC=11 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Cyclization of a N-terminal glutamine (Conversion to pyrrolidone carboxylic acid)	Free	"There are four disulfide bonds between Cys4 and Cys51, Cys15 and Cys36, Cys21 and Cys45, Cys25 and Cys47."	L	No cytotoxicity information found	Not found	7780308	Plant Cell. 1995 May;7(5):573-588.	"Terras FR, Eggermont K, Kovaleva V, Raikhel NV, Osborn RW, Kester A, Rees SB, Torrekens S, Van Leuven F, Vanderleyden J, et al."	Small cysteine-rich antifungal proteins from radish: their role in host defense.
DRAMP00422	QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC	51	Defensin-like protein 1 (Sa-AFP1; Plant defensin)	P30231	Belongs to the DEFL family	Not found	Sinapis alba (White mustard) (Brassica hirta)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	Function: Possesses antifungal activity sensitive to inorganic cations.	"Fungi: Alternaria brassicola (MIC=1.2 ?g/ml), Botrytis cinerea (MIC=1.8 ?g/ml), Fusarium culmorum (MIC=4 ?g/ml), Fusarium oxysporum f.sp.lycopersici (MIC=6 ?g/ml), Pyricularia oryzae (MIC=0.5 ?g/ml), Verticillium dahliae (MIC=1.5 ?g/ml).##NOTE: In synthetic low ionic strength fungal growth medium."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Cyclization of a N-terminal glutamine (Conversion to pyrrolidone carboxylic acid)	Free	"There are four disulfide bonds between Cys4 and Cys51, Cys15 and Cys36, Cys21 and Cys45, Cys25 and Cys47."	L	No cytotoxicity information found	Not found	8422949##8836771	FEBS Lett. 1993 Feb 1;316(3):233-240.##Int J Pept Protein Res. 1996 Jun;47(6):437-446.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Neumann GM, Condron R, Polya GM."	A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Purification and mass spectrometry-based sequencing of yellow mustard (Sinapis alba L.) 6 kDa proteins. Identification as antifungal proteins.
DRAMP00423	QKLCQRPSGTWSGVCGNNNACRNQCINLEKARHGSCNYVFPAHKCICYFPC	50	Defensin-like protein 2 (Sa-AFP2; Plant defensin)	P30232	Not found	Not found	Sinapis alba (White mustard) (Brassica hirta)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Function: Possesses antifungal activity sensitive to inorganic cations.	"Fungi: Alternaria brassicola (MIC=4.5 ?g/ml), Botrytis cinerea (MIC=3.5 ?g/ml), Fusarium culmorum (MIC=2.3 ?g/ml), Fusarium oxysporum f.sp.lycopersici (MIC=2.3 ?g/ml), Pyricularia oryzae (MIC=0.3 ?g/ml), Verticillium dahliae (MIC=1.2 ?g/ml).##NOTE: In synthetic low ionic strength fungal growth medium."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Cyclization of a N-terminal glutamine (Conversion to pyrrolidone carboxylic acid)	Free	"¢ÙThere are four disulfide bonds between Cys4 and Cys51, Cys15 and Cys36, Cys21 and Cys45, Cys25 and Cys47. ¢ÚThe residue at position 8 is phosphorylated."	L	No cytotoxicity information found	Not found	8422949	FEBS Lett. 1993 Feb 1;316(3):233-240.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF."	A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
DRAMP00425	LMCTHPLDCSN	11	Tn-AFP1 (Trapa natans antifungal peptide; Plant defensin)	No entry found	Not found	Not found	Trapa natans	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Function: Tn-AFP1 has no adverse effect on red blood cells at concentration of 32 ¦Ìg/mL.	Yeast: Candida tropicalis (MIC=32 ?g/ml).	Tn-AFP1 has no adverse effect on red blood cells at concentration of 32 ¦Ìg mL?1	Cyclic	Free	Free	There is a disulfide bond between Cys3 and Cys9	L	No cytotoxicity information found	Not found	21736910	Peptides. 2011 Aug;32(8):1741-1747.	"Mandal SM, Migliolo L, Franco OL, Ghosh AK."	Identification of an antifungal peptide from Trapa natans fruits with inhibitory effects on Candida tropicalis biofilm formation.
DRAMP00436	KTCEHLADTYRGVCFTNASCDDHCKNKAHLISGTCHNWKCFCTQNC	46	Pisum sativum defensin 1 (Psd1; Plant defensin)	P81929	Belongs to the DEFL family	Not found	Pisum sativum (Garden pea)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	The protein has a globular fold with a triple-stranded antiparalell beta-sheet and an alpha-helix (from residue Asn17 to Leu27). 	1JKZ resolved by NMR.	PTM: Contains four disulfide bonds 3-46; 14-35; 20-40; 24-42.	"PD: Aspergillus niger (MIC=12.1 ?g/ml), Aspergillus versicolor (MIC<5.0 ?g/ml), Fusarium moniliforme (MIC=21.7 ?g/ml), Fusarium oxysporum (MIC>100 ?g/ml), Fusarium solani (MIC=12.1 ?g/ml), Neurospora crassa (MIC=0.04 ?g/ml), Saccharomyces cerevisae (MIC>100 ?g/ml), Trichophyton mentagrophytes (MIC>100 ?g/ml).##PD+: Aspergillus niger (MIC=7.4 ?g/ml), Fusarium moniliforme (MIC=33.2 ?g/ml), Fusarium oxysporum (MIC=100 ?g/ml), Fusarium solani (MIC=79.2 ?g/ml), Neurospora crassa (MIC=0.05 ?g/ml).##NOTE: PD+: potato dextrose medium supplemented with 1 mM CaCl2."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization of a C-terminal Cys residue (forming a disulfide bond)	"There are four disulfide bonds between Cys3 and Cys46, Cys14 and Cys35, Cys20 and Cys40, Cys24 and Cys42"	L	No cytotoxicity information found	It interacts with cell-cycle-realted protein cyclin F as the target.	10860545##11697857##11812144	Arch Biochem Biophys. 2000 Jun 15;378(2):278-286.##Arch Biochem Biophys. 2001 Nov 15;395(2):199-207.##J Mol Biol. 2002 Jan 25;315(4):749-757.	"Almeida M.S, Cabral K.M, Zingali R.B, Kurtenbach E.##Almeida MS, Cabral KS, de Medeiros LN, Valente AP, Almeida FC, Kurtenbach E.##Almeida MS, Cabral KM, Kurtenbach E, Almeida FC, Valente AP."	"Characterization of two novel defense peptides from pea (Pisum sativum) seeds.##cDNA cloning and heterologous expression of functional cysteine-rich antifungal protein Psd1 in the yeast Pichia pastoris.##Solution structure of Pisum sativum defensin 1 by high resolution NMR: plant defensins, identical backbone with different mechanisms of action."
DRAMP00437	KTCENLSGTFKGPCIPDGNCNKHCRNNEHLLSGRCRDDFRCWCTNRC	47	Pisum sativum defensin 2 (Psd2; Plant defensin)	P81930	Belongs to the DEFL family	Not found	Pisum sativum (Garden pea)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	PTM: Contains four disulfide bonds 3-47; 14-35; 20-41; 24-43.	"PD: Aspergillus niger (MIC=10.2 ?g/ml), Aspergillus versicolor (MIC=0.34 ?g/ml), Fusarium moniliforme (MIC=10.0 ?g/ml), Fusarium oxysporum (MIC>100 ?g/ml), Fusarium solani (MIC=8.5 ?g/ml), Neurospora crassa (MIC<0.5 ?g/ml), Saccharomyces cerevisae (MIC>100 ?g/ml), Trichophyton mentagrophytes (MIC<100 ?g/ml).##PD+: Aspergillus niger (MIC=7.8 ?g/ml), Aspergillus versicolor (MIC=5.9 ?g/ml), Fusarium moniliforme (MIC=25 ?g/ml), Fusarium oxysporum (MIC>100 ?g/ml), Fusarium solani (MIC=5.0 ?g/ml).##NOTE: PD+ = potato dextrose medium supplemented with 1 mM CaCl2."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization of a C-terminal Cys residue (forming a disulfide bond)	"There are four disulfide bonds between Cys3 and Cys47, Cys14 and Cys35, Cys20 and Cys41, Cys24 and Cys43."	L	No cytotoxicity information found	Not found	10860545	Arch Biochem Biophys. 2000 Jun 15;378(2):278-286.	"Almeida M.S, Cabral K.M, Zingali R.B, Kurtenbach E."	Characterization of two novel defense peptides from pea (Pisum sativum) seeds.
DRAMP00450	QKLCQRPSGTWSGVCGNNNACRNQCINLEKARHGSCNYVFPAHKCICYFPC	51	Defensin-like protein 2A (AFP2A; M2A; Plant defensin)	P30232	Belongs to the DEFL family	Not found	Sinapis alba (White mustard) (Brassica hirta)	"Antimicrobial, Antifungal"	Protein level	Rich	Not found	None	"Function: Possesses antifungal activity sensitive to inorganic cations.
Subunit structure: Forms oligomers in its native state.
PTM: Contains four disulfide bonds (By similarity)."	"Fungi: Alternaria brassicola (MIC=4.5 ?g/ml), Botrytis cinerea (MIC=3.5 ?g/ml), Fusarium culmorum (MIC=2.3 ?g/ml), Fusarium oxysporum f.sp. lycopersici (MIC=2.3 ?g/ml), Pyricularia oryzae (MIC=0.3 ?g/ml), Verticillium dahliae (MIC=1.2 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	[Ref.8422949] Cyclization of a N-terminal glutamine (Conversion to pyrrolidone carboxylic acid)	Cyclization of a C-terminal Cys residue (forming a disulfide bond)	"¢ÙThere are four disulfide bonds between Cys4 and Cys51, Cys15 and Cys36, Cys21 and Cys45, Cys25 and Cys47. ¢Ú[Ref.8836771] The residue at position 8 is phosphorylated."	L	No cytotoxicity information found	Not found	8422949##8836771	FEBS Lett. 1993 Feb 1;316(3):233-240.##Int J Pept Protein Res. 1996 Jun;47(6):437-446.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Neumann GM, Condron R, Polya GM."	A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Purification and mass spectrometry-based sequencing of yellow mustard (Sinapis alba L.) 6 kDa proteins. Identification as antifungal proteins.
DRAMP00454	ATCKAECPTWDSVCINKKPCVACCKKAKFSDGHCSKILRRCLCTKEC	47	Petunia hybrida defensin 1 (PhD1; Cys-rich; Plant defensin)	Q8H6Q1	Belongs to the DEFL family	D1	Petunia hybrida (Petunia)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	"PhD1 has the fold of the cysteine-stabilized alphabeta motif, consisting of an alpha-helix and a triple-stranded antiparallel beta-sheet, except that it contains a fifth disulfide bond from the first loop to the alpha-helix."	1N4N resolved by NMR.	"Function: Plant defense peptide with antifungal activity.
Tissue specificity: Petals.
Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.
Biophysicochemical properties: pH dependence (Stable under extremes of pH); Temperature dependence (Stable under extremes of temperature).
PTM: Contains five disulfide bonds 3-47; 7-23; 14-34; 20-41; 24-43."	"Fungi: Fusarium oxysporum (MIC=10 ?g/ml), Botrytis cinerea (MIC=10 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"When compared to other plant defensins, the petunia defensins have an additional fifth disulfide bond. There are five disulfide bonds between Cys3 and Cys47, Cys7 and Cys23, Cys14 and Cys34, Cys20 and Cys41, Cys24 and Cys43."	L	No cytotoxicity information found	Not found	12644678##12846570	Plant Physiol. 2003 Mar;131(3):1283-1293.##Biochemistry. 2003 Jul 15;42(27):8214-8222.	"Lay FT, Brugliera F, Anderson MA.##Janssen BJ, Schirra HJ, Lay FT, Anderson MA, Craik DJ."	"Isolation and properties of floral defensins from ornamental tobacco and petunia.##Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds."
DRAMP00764	KSLRPRCWIKIKFRCKSLKF	20	Piceain 1 (Plants)	No entry found	Not found	Not found	Picea sitchensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Beta strand (CD)	Not found	None	"Function: Active against both Gram-postive and Gram-negative bacteria, fungi. It showed weak hemolysis activity against human and rabbit red cells.
PTM: Contains one disulfide bond."	"Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=9.38 ?g/ml), S. aureus ATCC 43300 (MIC=9.38 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=18.75 ?g/ml), Escherichia coli ML-35P (MIC=18.75 ?g/ml), Escherichia coli 08040722 (CI) (MIC=75 ?g/ml), Escherichia coli 08A866 (CI) (MIC=37.5 ?g/ml), Pseudomonas aeruginosa PA01 (MIC=9.38 ?g/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=9.38 ?g/ml), Pseudomonas aeruginosa 08031014 (CI) (MIC=37.5 ?g/ml).##Yeast: Candida albicans ATCC 20032 (MIC=9.38 ?g/ml)."	"[Ref.21644248] At the concentration of 0.0625 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 0.7% & 1.5%; At the concentration of 0.125 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 0.8% & 7.2%; At the concentration of 0.25 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 5.9%&7.8%; At the concentration of 0.5 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 7.6% & 9.5%; At the concentration of 1 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 7.8% & 57.1%."	Cyclic	Free	Free	There is one intra-molecular disulfide bridge formed by Cys7 and Cys15.	L	No cytotoxicity information found	Not found	21644248	J Pept Sci. 2011 Sep;17(9):627-631.	"Liu R, Mu L, Liu H, Wei L, Yan T, Chen M, Zhang K, Li J, You D, Lai R."	Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis.
DRAMP00765	RPRCWIKIKFRCKSLKF	17	Piceain 2 (Plants)	No entry found	Not found	Not found	Picea sitchensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Active against both Gram-postive and Gram-negative bacteria, fungi. It showed weak hemolysis activity against human and rabbit red cells.
PTM: Contains one disulfide bond."	"Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=9.38 ?g/ml), S. aureus ATCC 43300 (MIC=18.75 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=37.5 ?g/ml), Escherichia coli ML-35P (MIC=37.5 ?g/ml), Escherichia coli 08040722 (CI) (MIC=75 ?g/ml), Escherichia coli 08A866 (CI) (MIC=37.5 ?g/ml), Pseudomonas aeruginosa PA01 (MIC=9.38 ?g/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=18.75 ?g/ml), Pseudomonas aeruginosa 08031014 (CI) (MIC=37.5 ?g/ml).##Yeast: Candida albicans ATCC 20032 (MIC=18.75 ?g/ml)."	"[Ref.21644248] At the concentration of 0.0625 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 0.6% & 2.2%; At the concentration of 0.125 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 0.8% & 4.7%; At the concentration of 0.25 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 5.2%&5.2%; At the concentration of 0.5 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 5.3% & 12.4%; At the concentration of 1 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 11.3% & 66.3%."	Cyclic	Free	Free	There is one intra-molecular disulfide bridge formed by Cys4 and Cys12.	L	No cytotoxicity information found	Not found	21644248	J Pept Sci. 2011 Sep;17(9):627-631.	"Liu R, Mu L, Liu H, Wei L, Yan T, Chen M, Zhang K, Li J, You D, Lai R."	Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis.
DRAMP00856	GLPVCGETCVGGTCNTPGCTCSWPVCTRN	29	Kalata-B1 (Plant defensin)	P56254	Belongs to the cyclotide family	OAK1	Oldenlandia affinis 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral"	Protein level	Beta strand (3 strands; 7 residues)	Not found	2KHB resolved by NMR.	"Function: Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S. aureus. Relatively ineffective against Gram-negative bacteria such as E. coli and P. aeruginosa. Inhibitory effect on the growth and development of larvae from H. punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost.
MOA: a small number of cyclotides bind to the membrane surface and then insert first into the outer membrane leaflet followed by penetration through the membrane and pore formation. At higher concentrations of cyclotides, destabilization of membranes occurs.
Tissue specificity: Leaves and stems. Lower in roots.
Pharmaceutical use: The uteroactive properties of Kalata have been discovered by African traditional medicine. It is used as an ingredient of a herbal tea to accelerate childbirth.
PTM: Kalata-B1 is a cyclic peptide which contains three disulfide bonds 5-19; 11-21; 14-26."	"[Ref.10430870]Gram-positive bacterium: Staphylococcus aureus (MIC=0.26 ?M), Micrococcus luteus (MIC=40.4 ?M);##Gram-negative bacterium: Klebsiella oxytoca (MIC=54.8 ?M);##Fungi: Candida kefyr (MIC=21.4 ?M).##[Ref.18008336]Virus:HIV:inhibition the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells(EC50=140 nM)."	[Ref.12779323] HD50 = 300 ¦ÌM against Human type A red blood cells.	Cyclic	Cyclization (N termini to C termini)	Cyclization (C termini to N termini)	"[Ref.7703226] There are three disulfide bonds between Cys5 and Cys19, Cys9 and Cys21, Cys14 and Cys26."	L	[Ref.18008336]CEM-SS cells:IC50=3500 nM.	Cell membrance	18008336##10430870##7703226##17534989##23129773	Biopolymers. 2008;90(1):51-60.##Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8918.##Biochemistry. 1995 Apr 4;34(13):4147-4158.##Chembiochem. 2007 Jun 18;8(9):1001-1011.##J Biol Chem. 2012 Dec 21;287(52):43884-98. 	"Ireland DC, Wang CK, Wilson JA, Gustafson KR, Craik DJ. ##Tam JP, Lu YA, Yang JL, Chiu KW.##Saether O, Craik DJ, Campbell ID, Sletten K, Juul J, Norman DG.##Plan MR, G?ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ.##Wang CK, Wacklin HP, Craik DJ."	"Cyclotides as natural anti-HIV agents.##An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides.##Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1.##The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides.##Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane through hydrophobic and phosphoethanolamine-specific interactions."
DRAMP00877	GIPCGESCVWIPCISAALGCSCKNKVCYRN	30	Circulin-A (CIRA; Plant defensin)	P56871	Belongs to the cyclotide family	Not found	Chassalia parviflora 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral, Antifungal"	Protein level	Alpha helix (1 helices; 4 residues)	"The molecule is stabilised by three disulfide bonds, two of which form an embedded loop completed by the backbone fragments connecting the cysteine residues. A third disulfide bond threads through the centre of this loop to form a ""cystine-knot"" motif. This motif is present in a range of other biologically active proteins, including omega-contoxin GVIA and Cucurbita maxima trypsin inhibitor."	1BH4 resolved by NMR.	"Function: Probably participates in a plant defense mechanism. Has antibiotic activity. Inhibits the cytopathic effects and replication of the human immunodeficiency virus. Relatively ineffective against Gram-negative bacteria such as E. coli and P. aeruginosa.
PTM: This is a cyclic peptide which contains three disulfide bonds 1-17; 5-19; 10-24."	[Ref.10430870]Gram-positive bacterium: Staphylococcus aureus (MIC=0.19 ?M).##Gram-negative bacterium: Proteus vulgaris (MIC=54.6 ?M).##Fungi: Candida kefyr (MIC=18.6 ?M) and Candida tropicalis (MIC=19.4 ?M).##NOTE: Medium with 10 mM phosphate buffer.##[Ref.18008336]Virus:HIV:inhibition the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells(EC50=40-260 nM).	[Ref.10430870] EC50 = 1020 ¦ÌM against blood type A human erythrocytes.	Cyclic	Cyclization (N termini to C termini)	Cyclization (C termini to N termini)	"[Ref.8920961] There are three disulfide bonds between Cys4 and Cys20, Cys8 and Cys22, Cys13 and Cys27"	L	[Ref.18008336]CEM-SS cells:IC50=500 nM.	Not found	18008336##10430870##9878410##8920961	Biopolymers. 2008;90(1):51-60. doi: 10.1002/bip.20886. ##Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8918.##J. Mol. Biol. 1999; 285:333-345. ##Biochem Biophys Res Commun. 1996 Nov 12;228(2):632-8.	"Ireland DC, Wang CK, Wilson JA, Gustafson KR, Craik DJ.##Tam JP, Lu YA, Yang JL, Chiu KW.##Daly NL, Koltay A, Gustafson KR, Boyd MR, Casas-Finet JR, Craik DJ.##R Derua 1, K R Gustafson, L K Pannell"	"Cyclotides as natural anti-HIV agents.##An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides.##Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity.##Analysis of the disulfide linkage pattern in circulin A and B, HIV-inhibitory macrocyclic peptides"
DRAMP00878	GVIPCGESCVFIPCISTLLGCSCKNKVCYRN	31	Circulin-B (CIRB; Plant defensin)	P56879	Belongs to the cyclotide family	Not found	Chassalia parviflora 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral, Antifungal"	Protein level	Beta strand (5 strands; 10 residues)	Cyclotides are mini-proteins derived from plants that have the characteristic features of a head-to-tail cyclised peptide backbone and a knotted arrangement of their three disulfide bonds.	2ERI resolved by NMR.	"Function: Probably participates in a plant defense mechanism. Has antibiotic activity. Inhibits the cytopathic effects and replication of the human immunodeficiency virus. Active against both Gram-positive and Gram-negative bacteria.
PTM: This is a cyclic peptide which contains three disulfide bonds 5-21; 9-23; 14-28."	"[Ref.10430870]Gram-positive bacterium: (L-salt): Staphylococcus aureus (MIC=13.5 ?M).##Gram-negative bacteria: (L-salt, H-salt) (MIC ?M): Escherichia coli (0.41, >500), Pseudomonas aeruginosa (25.5, 48), Proteus vulgaris (6.8, >500), Klebsiella oxytoca (8.2, 15.6).##Fungi (H-salt): Candida kefyr (MIC=29 ?M).##NOTE: L-salt = Medium with 10 mM phosphate buffer; H-salt = L-salt supplemented with 100 mM NaCl.##[Ref.18008336]Virus:HIV:inhibition the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells(EC50=40-260 nM)."	[Ref.10430870] EC50 = 550 ¦ÌM against blood type A human erythrocytes.	Cyclic	Cyclization (N termini to C termini)	Cyclization (C termini to N termini)	"[Ref.8920961] There are three disulfide bonds between Cys5 and Cys19, Cys9 and Cys21, Cys14 and Cys27."	L	[Ref.10430870] It caused 50% cell growth inhibition of mouse fibroblasts at 820 ¦ÌM.##[Ref.18008336]CEM-SS cells:IC50=500 nM.	Not found	10430870##18008336##8920961	Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8918.##Biopolymers. 2008;90(1):51-60.##Biochem Biophys Res Commun. 1996 Nov 12;228(2):632-8. doi: 10.1006/bbrc.1996.1708.	"Tam JP, Lu YA, Yang JL, Chiu KW.##Ireland DC, Wang CK, Wilson JA, Gustafson KR, Craik DJ.##R Derua 1, K R Gustafson, L K Pannell"	"An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides.##Cyclotides as natural anti-HIV agents.##Analysis of the disulfide linkage pattern in circulin A and B, HIV-inhibitory macrocyclic peptides"
DRAMP01374	GFLDTFKNLALNAAKSAGVSVLNSLSCKLFKTC	33	"Odorranain-D1 (OdD1; Frogs, amphibians, animals)"	A6MBK7	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	Function: Odorranain-D1 exhibites antimicrobial activities against all of the tested microbes including Gram-positive and Gram-negative bacteria and fungi. Has no hemolytic activity against red cell.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=16.32 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=8.16 ¦Ìg/ml), Bacillus subtilis (MIC=8.16 ¦Ìg/ml).##Yeast: Candida albicans (MIC=4.08 ¦Ìg/ml)."	[Ref:17272268]Non-hemolytic activity against rabbit red blood cells	Cyclic	Free	Cyclization(Cys27 and Cys33)	Disulfide bridge between Cys27 and Cys33.	L	[Ref.17272268]No cytotoxicity information found	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01373	GVLGAVKDLLIGAGKSAAQSVLKTLSCKLSNDC	33	"Odorranain-C1 (OdC1; Frogs, amphibians, animals)"	A6MBF6	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	Function: Odorranain-C1 exhibites antimicrobial activities against all of the tested microbes including Gram-positive and Gram-negative bacteria and fungi.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=8.21 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=4.11 ¦Ìg/ml), Bacillus subtilis (MIC=16.42 ¦Ìg/ml).##Yeast: Candida albicans (MIC=2.05 ¦Ìg/ml)."	[Ref:17272268] No detectable hemolytic activity against rabbit red blood cells.	Cyclic	Free	Cyclization of a C-terminal Cys residue (forming a disulfide bond)	[Ref:17272268] There are one disulfide bond between Cys27 and Cys33	L	No cytotoxicity information found	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01372	AALKGCWTKSIPPKPCFGKR	20	"Odorranain-B1 (OdB1; Frogs, amphibians, animals)"	E7EKD9	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Odorrana hainanensis (Odor frog) (Rana hainanensis)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Homology	Not found	Odorranain-B1 adopts 5.9 % 	None	"Function: Odorranain-B1 exhibites antimicrobial activities against all of the tested microbes including Gram-positive and Gram-negative bacteria and fungi. Has no hemolytic activity against red cell. 
Tissue specificity: Expressed by the skin glands."	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=3.21 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=5.83 ¦Ìg/ml), Bacillus subtilis (MIC=1.85 ¦Ìg/ml).##Yeast: Candida albicans (MIC=2.4 ¦Ìg/ml)."	[Ref:17272268] No detectable hemolytic activity against rabbit red blood cells.	Cyclic	Free	Free	[Ref:17272268] There are one disulfide bond between Cys6 and Cys16	L	No cytotoxicity information found	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP00933	SAFTVWSGPGCNNRAERYSKCGCSAIHQKGGYDFSYTGQTAALYNQAGCSGVAHTRFGSSARACNPFGWKSIFIQC	76	Antimicrobial peptide 1 (AMP1; MiAMP1; Plant defensin)	P80915	Not found	Not found	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Combine helix and strand structure	MiAMP1 is made up of eight beta-strands which are arranged in two Greek key motifs. These Greek key motifs associate to form a Greek key beta-barrel. This structure is unique amongst plant antimicrobial proteins and forms a new class which we term the beta-barrelins. (Ref.2)	1C01 resolved by NMR.	"Function: Antimicrobial peptide which inhibits the growth of a variety of fungi, oomycetes, Gram-positive bacterial phytopatogenes and S.cerevisiae in vitro. No activity against E.coli.
Miscellaneous: Its antimicrobial activity is diminished by calcium an"	"Alternaria helianthi (MIC=2-5 ?g/ml), Botrytis cinerea (MIC=5-10 ?g/ml), Ceratocystis parodoxa (MIC=20 ?g/ml), Colletotrichum gloeosporioides (MIC=2-5 ?g/ml), Fusurium oxysporum (MIC=2-5 ?g/ml), Leptosphaeria maculans (MIC=5 ?g/ml), Macrophomina phaseolina (MIC<25 ?g/ml), Phytophthoru cryptogea (MIC=5-10 ?g/ml), Pythium graminicola (MIC=5 ?g/ml), Sclerotinia sclerotiorum spores (MIC=5 ?g/ml), Sclerotinia sclerotiorum mycelia (MIC=50 ?g/ml), Verticilium dahliae (MIC=2 ?g/ml), Clavibacter michiganensis (MIC<10 ?g/ml), Saccharomyces cerevisiae (MIC=2-5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization of a C-terminal Cys residue (forming a disulfide bond)	"[Ref.10543955] There are three disulfide bonds between Cys11 and Cys64, Cys21 and Cys76, Cys23 and Cys49"	L	No cytotoxicity information found	Not found	9108242##10543955	Eur J Biochem. 1997 Mar 15;244(3):743-749.##J Mol Biol. 1999 Oct 29;293(3):629-638.	"Marcus JP, Goulter KC, Green JL, Harrison SJ, Manners JM.##McManus AM, Nielsen KJ, Marcus JP, Harrison SJ, Green JL, Manners JM, Craik DJ."	"Purification, characterisation and cDNA cloning of an antimicrobial peptide from Macadamia integrifolia.##MiAMP1, a novel protein from Macadamia integrifolia adopts a Greek key beta-barrel fold unique amongst plant antimicrobial proteins."
DRAMP01004	PQRGEGGRAGNLLREEQEI	19	Cucurmoschin (Plants)	P84158	Not found	Not found	Cucurbita maxima (winter squash)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity. Inhibits cell-free translation in rabbit reticulocyte lysate system.	"Fungi: Botrytis cinerea (MIC=375 ?M), Fusarium oxysporum (MIC=375 ?M), Mycosphaerella arachidicola (MIC=375 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	None	L	No cytotoxicity information found	Not found	14499274	Peptides. 2003 Jul;24(7):969-972.	"Wang HX, Ng TB."	"Isolation of cucurmoschin, a novel antifungal peptide abundant in arginine, glutamate and glycine residues from black pumpkin seeds."
DRAMP01016	QCIGNGGRCNENVGPPYCCSGFCLRQPGQGYGYCKNR	37	Antimicrobial peptide 1 (MJ-AMP1; Plant defensin)	P25403	Belongs to the AMP family	AMP1	Mirabilis jalapa (Garden four-o'clock)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	"Function: Possesses antifungal activity and is also active on two tested Gram-positive bacteria: but is non-toxic for Gram-negative bacteria and cultured human cells. 
Tissue specificity: Found only in seeds.
PTM: Contains three disulfide bonds 2-19; 9-23;"	"Fungi: Alternaria brassicola (MIC=20 ?g/ml), Ascochyta pisi (MIC=200 ?g/ml), Botrytis cinerea (MIC=50 ?g/ml), Cercospora beticola (MIC=10 ?g/ml), Colletotrichum lindemuthianum (MIC=6 ?g/ml), Fusarium culmorum (MIC=30 ?g/ml), Fusarium oxysporum f.sp.pisi (MIC=15 ?g/ml), Fusarium oxysporum f.sp.lycopersici (MIC=200 ?g/ml), Nectria haematococca (MIC=15 ?g/ml), Phoma betae (MIC=25 ?g/ml), Pyrenophora tritici-repentis (MIC=300 ?g/ml), Pyricularia oryzae (MIC=6 ?g/ml), Rhizoctonia solani (MIC=60 ?g/ml), Verticillium dahliae (MIC=12 ?g/ml), Venturia inequalis (MIC=12 ?g/ml).##Gram-positive bacteria: Bacillus megaterium (MIC=6 ?g/ml), Sarcina lutea (MIC=100 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Pyroglutamyl modification (Cyclization of a N-terminal glutamine)	Free	"There are three disulfide bonds between Cys2 and Cys19, Cys9 and Cys23, Cys18 and Cys34."	L	No cytotoxicity information found	Not found	1733929##7647302	J. Biol. Chem. 1992;267:2228-2233.##Plant Mol. Biol. 1995;28:713-721.	"Cammue B.P.A, de Bolle M.F.C, Terras F.R.G, Proost P, van Damme J, Rees S.B, Vanderleyden J, Broekaert W.F.##de Bolle M.F, Eggermont K, Duncan R.E, Osborn R.W, Terras F.R.G, Broekaert W.F."	Isolation and characterization of a novel class of plant antimicrobial peptides from Mirabilis jalapa L. seeds.##Cloning and characterization of two cDNA clones encoding seed-specific antimicrobial peptides from Mirabilis jalapa L.
DRAMP01017	CIGNGGRCNENVGPPYCCSGFCLRQPNQGYGVCRNR	36	Antimicrobial peptide 2 (MJ-AMP2; Plant defensin)	P25404	Belongs to the AMP family	AMP2	Mirabilis jalapa (Garden four-o'clock)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge 	Not found	None	Function: Possesses antifungal activity and is also active on two tested Gram-positive bacteria: but is non-toxic for Gram-negative bacteria and cultured human cells. Tissue specificity: Found only in seeds. PTM: Contains three disulfide bonds 1-18; 8-22; 	"Fungi: Alternaria brassicola (MIC=6 ?g/ml), Ascochyta pisi (MIC=6 ?g/ml), Botrytis cinerea (MIC=2 ?g/ml), Cercospora beticola (MIC=2 ?g/ml), Colletotrichum lindemuthianum (MIC=1 ?g/ml), Fusarium culmorum (MIC=3 ?g/ml), Fusarium oxysporum f.sp.pisi (MIC=5 ?g/ml), Fusarium oxysporum f.sp.lycopersici (MIC=10 ?g/ml), Nectria haematococca (MIC=0.5 ?g/ml), Phoma betae (MIC=6 ?g/ml), Pyrenophora tritici-repentis (MIC=20 ?g/ml), Pyricularia oryzae (MIC=0.5 ?g/ml), Rhizoctonia solani (MIC=15 ?g/ml), Verticillium dahliae (MIC=0.5 ?g/ml), Venturia inequalis (MIC=1 ?g/ml).##Gram-positive bacteria: Bacillus megaterium (MIC=2 ?g/ml), Sarcina lutea (MIC=50 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Cyclization of a N-terminal Cys residue (forming a disulfide bond)	Free	"There are three disulfide bonds between Cys1 and Cys18, Cys8 and Cys22, Cys17 and Cys33."	L	No cytotoxicity information found	Not found	1733929##7647302	J Biol Chem. 1992 Feb 5;267(4):2228-2233.##Plant Mol Biol. 1995 Jul;28(4):713-721.	"Cammue BP, De Bolle MF, Terras FR, Proost P, Van Damme J, Rees SB, Vanderleyden J, Broekaert WF.##De Bolle MF, Eggermont K, Duncan RE, Osborn RW, Terras FR, Broekaert WF."	Isolation and characterization of a novel class of plant antimicrobial peptides form Mirabilis jalapa L. seeds.##Cloning and characterization of two cDNA clones encoding seed-specific antimicrobial peptides from Mirabilis jalapa L.
DRAMP01018	SIPCGESCVFIPCTVTALLGCSCKSKVCYKN	31	Cyclopsychotride-A (CPT; Plant defensin)	P56872	Not found	Not found	Psychotria longipes 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Function: Probably participates in a plant defense mechanism. Has antibiotic activity. Inhibits the cytopathic effects and replication of the human immunodeficiency virus. Active against both Gram-positive and Gram-negative bacteria.
PTM: This is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28."	"Gram-negative bacteria: Escherichia coli (MIC=1.55 ?M), Pseudomonas aeruginosa (MIC=13.5 ?M), Proteus vulgaris (MIC=13.2 ?M), Klebsiella oxytoca (MIC=5.80 ?M).##Gram-positive bacteria: Staphylococcus aureus (MIC=39.0 ?M), Micrococcus luteus (MIC=48.0 ?M).##Fungi: Candida albicans (MIC>500 ?M), Candida kefyr (MIC=14.0 ?M), Candida tropicalis (MIC=56.5 ?M).##NOTE: Medium with 10 mM phosphate buffer."	[Ref.10430870] HD50 = 405 ¦ÌM against blood type A human erythrocytes.	Cyclic	Cyclization (N termini to C termini)	Cyclization (C termini to N termini)	"There are three disulfide bonds between Cys4 and Cys21, Cys8 and Cys23, Cys13 and Cys28"	L	[Ref.10430870] It caused 50% cell growth inhibition of mouse fibroblasts at 1850 ¦ÌM.	Not found	10430870##7714530	Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8918.##J Nat Prod. 1994 Dec;57(12):1619-1625.	"Tam JP, Lu YA, Yang JL, Chiu KW.##Witherup KM, Bogusky MJ, Anderson PS, Ramjit H, Ransom RW, Wood T, Sardana M. "	"An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides.##Cyclopsychotride A, a biologically active, 31-residue cyclic peptide isolated from Psychotria longipes."
DRAMP01061	SRSELIVHQR	10	Antifungal peptide (Cm-p1; Plants)	B3EWI7	Not found	Not found	Cenchritis muricatus (Beaded periwinkle)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	2MP9 resolved by NMR.	Function: The synthetic peptide has antifungal activity. Has no antibacterial or cytotoxic activity.	"Fungi: Botrytis cinerea (MIC=20 ?M), Fusarium oxysporum (MIC=20 ?M), Aspergillus niger (MIC=41 ?M), Candida albicans 01U (MIC=13 ?M), C. albicans 38U (MIC=7 ?M), C. parapsilosis (MIC=105 ?M), C. neoformans strain L26 (MIC=209 ?M), C. neoformans strain L30 (MIC=209 ?M), Trichophyton rubrum (MIC=3 ?M)."	"[Ref.22210491] At the highest evaluated dose (256 ¦Ìg/mL), Cm-p1 showed no signs of toxicity against human red blood cells."	Linear	Free	Free (very possibly)	None	L	"[Ref.22210491] At the highest evaluated dose (256 ¦Ìg/mL), Cm-p1 showed no signs of toxicity against RAW 264.7 cells."	Not found	22210491	Biochimie. 2012 Apr;94(4):968-974.	"L¨®pez-Abarrategui C, Alba A, Silva ON, Reyes-Acosta O, Vasconcelos IM, Oliveira JT, Migliolo L, Costa MP, Costa CR, Silva MR, Garay HE, Dias SC, Franco OL, Otero-Gonz¨¢lez AJ."	Functional characterization of a synthetic hydrophilic antifungal peptide derived from the marine snail Cenchritis muricatus.
DRAMP01088	GFKEVLKADLGSLVKGIAAHVAN	23	"Alyteserin-1Ma (toads, amphibians, animals)"	No entry found	Not found	Not found	Alytes maurus (Midwife toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Alyteserin-1Ma has lower antimicrobial potencies (MIC>200 ?M).	Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=214 ?M) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=214 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	¦Á-Amidation	None	L	No cytotoxicity information found	Not found	22800568	Toxicon. 2012 Nov;60(6):967-981.	"K?nig E, Zhou M, Wang L, Chen T, Bininda-Emonds OR, Shaw C."	"Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): Implications for the evolution of frog skin defensive secretions."
DRAMP01089	GFKEVLKAGLGSLVKGIPAHVAN	23	"Alyteserin-1Mb (toads, amphibians, animals)"	No entry found	Not found	Not found	Alytes maurus (Midwife toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Alyteserin-2Ma has lower antimicrobial potencies (MIC>200 ?M).	Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=217 ?M) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=434 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	¦Á-Amidation	None	L	No cytotoxicity information found	Not found	22800568	Toxicon. 2012 Nov;60(6):967-981.	"K?nig E, Zhou M, Wang L, Chen T, Bininda-Emonds OR, Shaw C."	"Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): Implications for the evolution of frog skin defensive secretions."
DRAMP01090	FIGKLISAASGLLSHL	16	"Alyteserin-2Ma (toads, amphibians, animals)"	No entry found	Not found	Not found	Alytes maurus (Midwife toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial activity against the Gram-negative bacteria E. coli and Gram-positive bacteria S. aures. It only inhibits C. albicans at very high concentration of 150 microM.	Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=38.4 ?M) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=9.5 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	¦Á-Amidation	None	L	No cytotoxicity information found	Not found	22800568	Toxicon. 2012 Nov;60(6):967-981.	"K?nig E, Zhou M, Wang L, Chen T, Bininda-Emonds OR, Shaw C."	"Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): Implications for the evolution of frog skin defensive secretions."
DRAMP01091	ILGAIIPLVSGLLSHL	16	"Alyteserin-2Mb (toads, amphibians, animals)"	No entry found	Not found	Not found	Alytes maurus (Midwife toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial activity against the Gram-positive bacteria S. aures. It only inhibits C. albicans at very high concentration of 310 microM.	Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=19.3 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	¦Á-Amidation	None	L	No cytotoxicity information found	Not found	22800568	Toxicon. 2012 Nov;60(6):967-981.	"K?nig E, Zhou M, Wang L, Chen T, Bininda-Emonds OR, Shaw C."	"Antimicrobial peptides and alytesin are co-secreted from the venom of the Midwife toad, Alytes maurus (Alytidae, Anura): Implications for the evolution of frog skin defensive secretions."
DRAMP01096	GIGSAILSAGKSALKGLAKGLAEHFAN	27	"Bombinin-like peptide 2 (BLP-2; toads, amphibians, animals)"	P29003	Belongs to the bombinin family	Not found	Bombina orientalis (Oriental fire-bellied toad)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Has antimicrobial activity, but no hemolytic activity. Preference on killing Gram-negative non-enteric bacteria.
Tissue specificity: Expressed by the skin glands."	"[Ref.1744108]Gram-negative bacterium: 58% inhibition Neisseria meningitidis 118V C (MIC=20 ?g/ml), 98% inhibition Neisseria meningitidis 15240 IAI (MIC=20 ?g/ml), 98% inhibition Neisseria meningitidis 126E IC1 (MIC=20 ?g/ml), 97% inhibition Neisseria gonorrhoeoe F62 (MIC=20 ?g/ml), 99% inhibition Neisseria Iactamica 15323 (MIC=20 ?g/ml), 100% inhibition Neisseria Iactamica 15215A (MIC=20 ?g/ml), 95% inhibition Neisseria cinerea 15461 (MIC=20 ?g/ml)."	[Ref:1744108] No significant hemolytic activity was found which suggests a selectivity for prokaryotic over eukaryotic membranes.	Cyclic	Free	Amidation	None	L	No cytotoxicity information found	Not found	1744108	J. Biol. Chem. 1991; 266: 23103-23111.	"Gibson BW, Tang D, Mandrell R, Kelly M, Spindel ER."	"Bombinin-like peptides with antimicrobial activity from skin secretions of the Asian toad, Bombina orientalis."
DRAMP03017	FMPIIGRLMSGSL	13	"VESP-VB1 (Insects, animals)"	No entry found	Not found	Not found	vespine wasps Vespa bicolor	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Has antimicrobial activities against standard strains and strong antimicrobial ability against drug-resistant strains. Among the tested drug-resistant strains, Pseudemonas aeruginosa and Staphylococcus aureus were the most sensitive for this kind of antimicrobial peptide. Has a little hemolytic activity."	"[Ref.18723059] Gram-negative bacterium: Escherichia coli ATCC25922(MIC=7.5¦Ìg/ml), Escherichia coli 23A(MIC=7.5¦Ìg/ml), Escherichia coli 27A(MIC=15.0¦Ìg/ml), Pseudemonas aeruginosa 3A(MIC=3.75¦Ìg/ml), Pseudemonas aeruginosa 7A(MIC=3.75¦Ìg/ml), ;## Gram-positive bacterium: Staphylococcus aureus ATCC2592(MIC=1.9¦Ìg/ml), Staphylococcus aureus 6A(MIC=3.75¦Ìg/ml), Staphylococcus aureus 15A(MIC=1.0¦Ìg/ml);## Fungus: Candida albicans ATCC2002(MIC=30.0¦Ìg/ml)"	"[Ref.18723059] VESP-VB1 had a little hemolytic activity of 10.2% against rabbit red blood cells, and of 3.2% against human red blood cells with peptide concentration up to 200 ¦Ìg/ml"	Linear	Free	Free	None	L	No cytotoxicity information found	Not found	18723059	Peptides. 2008 Nov;29(11):1887-1892.	"Chen W, Yang X, Yang X, Zhai L, Lu Z, Liu J, Yu H."	Antimicrobial peptides from the venoms of Vespa bicolor Fabricius.
DRAMP01518	GILSLFTGGIKALGKTLFKMAGKAGAEHLACKATNQC	37	"Esculentin-2L (Frogs, amphibians, animals)"	P82827	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana luteiventris (Great Basin spotted frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against the Gram-positive, Gram-negative bacteria and fungi.
Tissue specificity: Expressed by the skin glands."	[Ref.10651828]Gram-positive bacterium: Staphylococcus aureus (MIC=3 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=6 ¦ÌM).##Yeast: Candida albicans (MIC=53 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization of a C-terminal Cys residue (forming a disulfide bond)	There is a disulfide bond between Cys31 and Cys37.	L	No cytotoxicity information found	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP01516	GLFSILRGAAKFASKGLGKDLTKLGVDLVACKISKQC	37	"Esculentin-2B (Frogs, amphibians, animals)"	P82839	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana berlandieri (Rio Grande leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against the Gram-positive, Gram-negative bacteria and fungi. 
Tissue specificity: Expressed by the skin glands."	[Ref.10651828]Gram-positive bacterium: Staphylococcus aureus (MIC=1 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=1 ¦ÌM).##Yeast: Candida albicans (MIC=29 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization of a C-terminal Cys residue (forming a disulfide bond)	There is a disulfide bond between Cys31 and Cys37.	L	No cytotoxicity information found	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP02077	FLPIIAGIAAKVFPKIFCAISKKC	24	"Brevinin-1Pb (Frogs, amphibians, animals)"	Q8QFQ5	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pipiens (Northern leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against the Gram-positive, Gram-negative bacteria and fungi.
Tissue specificity: Expressed by the skin glands."	[Ref.10651828]Gram-positive bacterium: Staphylococcus aureus (MIC=5 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=14 ¦ÌM).##Yeast: Candida albicans (MIC=7 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization of a C-terminal Cys residue (forming a disulfide bond)	There is a disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	10651828##12413397	Eur J Biochem. 2000 Feb;267(3):894-900.##Biochem J. 2003 Apr 1;371(Pt 1):125-130.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM.##Chen T, Farragher S.M, Bjourson A.J, Orr D.F, Rao P, Shaw C."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.##Granular gland transcriptomes in stimulated amphibian skin secretions."
DRAMP01162	AGRGKQGGKVRAKAKTRSSRAGLQFPVGRVHRLLRKGNY	39	"Buforin-1 (Buforin I; Fragment of Histone H2A; toads, amphibians, animals)"	P55897	Belongs to the histone H2A family	Not found	Bufo gargarizans (Asian toad) (Bufo bufo gargarizans)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
PTM: Monoubiquitination of C-terminus gives a specific tag for epigenetic transcriptional repression. Following DNA double-strand breaks (DSBs), it is ubiquitinated through 'Lys-63' linkage of ubiquitin moieties."	"Gram-positive bacteria: Bacillus subtilis (MIC=4 ?g/ml), Staphylococcus aureus (MIC=4 ?g/ml), Streptococcus mutans (MIC=8 ?g/ml), Streptococcus pneumoniae (MIC=4 ?g/ml), Pseudomonas putida (MIC=4 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=8 ?g/ml), Salmonella typhimurium (MIC=4 ?g/ml), Serratia sp. (MIC=8 ?g/ml).##Fungi: Candida albicans (MIC=4 ?g/ml), Cryptococcus neoformans (MIC=4 ?g/ml), Saccharomyces cerevisiae (MIC=4 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	¢ÙThe residue at position 5 is N6-(2-hydroxyisobutyryl)lysine or N6-acetyllysine. ¢ÚThe residue at position 9 is N6-(2-hydroxyisobutyryl)lysine or N6-lactoyllysine or N6-succinyllysine. ¢ÛThe Lys13 has a interchain with G-Cter in ubiquitin. ¢ÜThe Lys15 has a interchain with G-Cter in ubiquitin. ¢ÝThe residue at position 36 is N6-(2-hydroxyisobutyryl)lysine.	L	No cytotoxicity information found	DNA	8573171##8946958	Biochem Biophys Res Commun. 1996 Jan 5;218(1):408-413.##FEBS Lett. 1996 Nov 25;398(1):87-90.	"Park C.B, Kim M.S, Kim S.C.##Yi G.-S, Park C.B, Kim S.C, Cheong C."	A novel antimicrobial peptide from Bufo bufo gargarizans.##Solution structure of an antimicrobial peptide buforin II.
DRAMP01163	TRSSRAGLQFPVGRVHRLLRK	21	"Buforin-2 (Buforin II; Fragment of Histone H2A; toads, amphibians, animals)"	P0DQL2	Belongs to the histone H2A family	Not found	Bufo gargarizans (Asian toad) (Bufo bufo gargarizans)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Both buforin II and its derivative buforin IIb (sequence: RAGLQFPVGRLLRRLLRRLLR) showed selective anticancer activity against 62 cancer cell lines (Lee 2008 Cancer Lett 271: 47-51). Buforin II is more potent than buforin I.
PTM: Monoubiquitination of C-terminus gives a specific tag for epigenetic transcriptional repression. Following DNA double-strand breaks (DSBs), it is ubiquitinated through 'Lys-63' linkage of ubiquitin moieties."	"Gram-positive bacteria: Bacillus subtilis (MIC=2 ?g/ml), Staphylococcus aureus (MIC=4 ?g/ml), Streptococcus mutans (MIC=2 ?g/ml), Streptococcus pneumoniae (MIC=4 ?g/ml), Pseudomonas putida (MIC=2 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=4 ?g/ml), Salmonella typhimurium (MIC=1 ?g/ml), Serratia sp. (MIC=4 ?g/ml).##Fungi: Candida albicans (MIC=1 ?g/ml), Cryptococcus neoformans (MIC=1 ?g/ml), Saccharomyces cerevisiae (MIC=1 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	¢Ù The residue at position 21 is N6-(2-hydroxyisobutyryl)lysine	L	No cytotoxicity information found	DNA	8573171##8946958	Biochem Biophys Res Commun. 1996 Jan 5;218(1):408-413.##FEBS Lett. 1996 Nov 25;398(1):87-90.	"Park C.B, Kim M.S, Kim S.C.##Yi G.-S, Park C.B, Kim S.C, Cheong C."	A novel antimicrobial peptide from Bufo bufo gargarizans.##Solution structure of an antimicrobial peptide buforin II.
DRAMP01188	LALKSGGWLRLFGLKDKKH	19	"Chensinin-1ZHa (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana zhenhaiensis (Chinese brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=17 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=35 ?M), Pseudomonas aeruginosa ATCC 9027 (MIC=9 ?M).##Yeast: Candida albicans ATCC 2002 (MIC=35 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.22943378]No cytotoxicity information found	Not found	22943778	Zoolog Sci. 2012 Sep;29(9):553-558.	"Xu B, Che H, Kang L, Zheng S, Mu S, Wan F."	"Molecular Cloning and Functional Characterization of Novel Antimicrobial Peptides from the Skin of Brown Frog, Rana zhenhaiensis."
DRAMP01189	ATNIPFKVHFRCKAAFC	17	"Andersonin-W1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=23.5 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC>47 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC>47 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=47 ?g/ml)."	[Ref:22029824] It has no hemolytic activity against human red blood cells	Cyclic	Free	Cyclization (Cys12 and Cys17)	Disulfide bond between Cys12 and Cys17.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01190	AVNIPFKVHFRCKAAFC	17	"Andersonin-W2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=20.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=40.4 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=10.1 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=20.2 ?g/ml)."	[Ref:22029824] It has no hemolytic activity against human red blood cells	Cyclic	Free	Cyclization (Cys12 and Cys17)	Disulfide bond between Cys12 and Cys17.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01191	GLFSKFAGKGIVNFLIEGVE	20	"Andersonin-X1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30.5 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=15.3 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=15.3 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=30.5 ?g/ml)."	[Ref:22029824]Not found	Linear	Free	Free	Free	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01192	FLPKLFAKITKKNMAHIR	18	"Andersonin-Y1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=3.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=1.6 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=1.6 ?g/ml)."	[Ref:22029824]Not found	Linear	Free	Free	Free	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01194	TSRCIFYRRKKCS	13	"Andersonin-C1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Show hemolytic activity against human red blood cells and obvious insulin-stimulating activity at the concentration of 50 ??g/mL.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=30 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC>120 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=30 ?g/ml)."	[Ref:22029824] It has 15.2¡À2.1% hemolytic activity at 50¦Ìg/ml against human red blood cells	Cyclic	Free	Free	Disulfide bond between Cys4 and Cys12.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01195	FIFPKKNIINSLFGR	15	"Andersonin-D1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Weakly active against bacteria and fungi. Andersonin-D1 showes obvious insulin-stimulating activity at the concentration of 50 ??g/mL.	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC>126 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=16 ?g/ml); ##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=16 ?g/ml).##Yeast: Candida albicans ATCC 2002 (MIC=16 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	Free	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01199	RFIYMKGFGKPRFGKR	16	"Hejiangin-A1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana hejiangensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Hejiangin-A1 showes killing effects against the tested strains.	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=100 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=25 ?g/ml); ##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=25 ?g/ml).##Yeast: Candida albicans ATCC 2002 (MIC=50 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	Free	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01200	IPWKLPATFRPVERPFSKPFCRKD	24	"Hejiangin-F1 (frog, amphibians, animals)"	No entry found	Not found	Not found	Odorrana hejiangensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Weakly active against bacteria and fungi and has no hemolytic activity under the test conditions.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC>100 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=100 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=100 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=100 ?g/ml)."	[Ref:22029824]Non-hemolytic activity against human red blood cells	Linear	Free	Free	Free	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01201	AAPRGGKGFFCKLFKDC	17	"Schmackerin-C1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana schmackeri	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Schmackerin-C1 showes killing effects against the tested strains. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=100 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=50 ?g/ml); ##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=50 ?g/ml).##Yeast: Candida albicans ATCC 2002 (MIC=100 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys11 and Cys17)	Disulfide bond between Cys11 and Cys17.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01208	SIITMTKEAKLPQLWKQIACRLYNTC	26	"Pleurain-A1 (Pleurain A1; Frogs, amphibians, animals)"	"A8DY01, A8DY00, A8DY02, A8DY03, A8DY04, A8DY09, A8DY10, A8DY15"	Not found	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has little hemolytic activity on red blood cells.
Tissue specificity: Expressed by the skin dorsal glands."	"[Ref.17764786]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=60 ?g/ml), Helicobacter pylori NCTC 11637 (MIC=30 ?g/ml);##Gram-positive bacteria: Bacillus dysenteriae (MIC=120 ?g/ml), Staphylococcus aureus ATCC 2592 (MIC=15 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=30 ?g/ml).."	[Ref:17764786] It has little hemolytic activity on red blood cells even with peptide concentration up to 200 ¦Ìg/ml	Cyclic	Free	Cyclization (Cys20 and Cys26)	Disulfide bond between Cys20 and Cys26.	L	No cytotoxicity information found	Not found	17764786	Peptides. 2007 Oct;28(10):2069-2074.	"Wang X, Song Y, Li J, Liu H, Xu X, Lai R, Zhang K."	A new family of antimicrobial peptides from skin secretions of Rana pleuraden
DRAMP01209	SIITMTKEAKLPQSWKQIACRLYNTC	26	"Pleurain-A2 (Pleurain A2; Frogs, amphibians, animals)"	A8B5P0	Not found	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has little hemolytic activity on red blood cells.
Tissue specificity: Expressed by the skin dorsal glands."	"[Ref.17764786]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=60 ?g/ml), Helicobacter pylori NCTC 11637 (MIC=30 ?g/ml);##Gram-positive bacteria: Bacillus dysenteriae (MIC=60 ?g/ml), Staphylococcus aureus ATCC 2592 (MIC=15 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=30 ?g/ml)."	[Ref:17764786] It has little hemolytic activity on red blood cells even with peptide concentration up to 200 ¦Ìg/ml	Cyclic	Free	Cyclization (Cys20 and Cys26)	Disulfide bond between Cys20 and Cys26.	L	No cytotoxicity information found	Not found	17764786	Peptides. 2007 Oct;28(10):2069-2074.	"Wang X, Song Y, Li J, Liu H, Xu X, Lai R, Zhang K."	A new family of antimicrobial peptides from skin secretions of Rana pleuraden.
DRAMP01218	GFMKYIGPLIPHAVKAISDLI	21	"Kassinatuerin-1 (Frogs, amphibians, animals)"	P0C010	Not found	Not found	Kassina senegalensis (Senegal running frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Shows broad-spectrum antimicrobial activity.
Tissue specificity: Expressed by the skin dorsal glands."	"Gram-negative bacteria: Escherichia coli (MIC=6.25 ?M), Klebsiella pneumoniae (MIC=25 ?M), Enterobacter cloacae (MIC=6.25 ?M), Pseudomonas aeruginosa (MIC=25 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=6.25 ?M), Staphylococcus epidermidis (MIC=6.25 ?M), Enterococcus faecalis (MIC=12.5 ?M).##Yeast: Candida albicans (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.15885852]Display cytotoxicity against L929 fibroblasts (LD50=12¦ÌM).	Not found	10679222##15885852	Biochem Biophys Res Commun. 2000 Feb 16;268(2):433-436.##Peptides. 2005 Nov;26(11):2104-2110.	"Mattute B, Knoop FC, Conlon JM.##Conlon JM, Abraham B, Galadari S, Knoop FC, Sonnevend A, P?l T."	"Kassinatuerin-1: a peptide with broad-spectrum antimicrobial activity isolated from the skin of the hyperoliid frog, Kassina senegalensis.##Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives."
DRAMP01237	GFMDTAKNVAKNVAVTLLDKLKCKITGGC	29	"Palustrin-2ISa (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana ishikawae	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=100 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=25 ?M), Staphylococcus aureus (MRSA) (MIC=100 ?M), Bacillus subtilis (MIC=12.5 ?M).##Yeast: Candida albicans (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys23 and Cys29)	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	21193000	Peptides. 2011 Apr;32(4):670-676. 	"Iwakoshi-Ukena E, Ukena K, Okimoto A, Soga M, Okada G, Sano N, Fujii T, Sugawara Y, Sumida M."	Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae.
DRAMP01251	VWPLGLVICKALKIC	15	"Dybowskin-4 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana dybowskii (Korea brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Dybowskin-4 has relatively greater hemolytic activity against human red blood cells (hRBCs).	"[Ref.17698251]Gram-positive bacteria: Micrococcus luteus ATCC4698 (MIC=1.56 ?g/ml), Staphylococcus aureus KCTC3881 (MIC=3.13 ?g/ml), Bacillus subtilis ATCC6633 (MIC=6.25 ?g/ml), Staphylococcus epidermidis ATCC12228 (MIC=6.25 ?g/ml);##Gram-negative bacteria: Shigella dysenteriae ATCC9752 (MIC=30 ?g/ml), Escherichia coli KCTC2433 (MIC=15 ?g/ml), Klebsiella pneumoniae ATCC10031 (MIC=15 ?g/ml);##Yeast: Candida albicans ATCC36232 (MIC=25 ?g/ml)."	[Ref:17698251] It has 47.58% hemolytic activity at 100 ¦Ìg/ml against human red blood cells	Cyclic	Free	Cyclization (Cys9 and Cys15)	Disulfide bond between Cys9 and Cys15.	L	No cytotoxicity information found	Not found	17698251	Peptides 2007; 28: 1532-1539. 	"Kim SS, Shim MS, Chung J, Lim DY, Lee BJ."	Purification and characterization of antimicrobial peptides from the skin secretion of Rana dybowskii.
DRAMP01252	GLFSVVTGVLKAVGKNVAKNVGGSLLEQLKCKKISGGC	38	"Dybowskin-5 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana dybowskii (Korea brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Dybowskin-5 has hemolytic activity against human red blood cells (hRBCs).	"[Ref.17698251]Gram-positive bacteria: Micrococcus luteus ATCC4698 (MIC=6.25 ?g/ml), Staphylococcus aureus KCTC3881 (MIC=25 ?g/ml), Bacillus subtilis ATCC6633 (MIC=50 ?g/ml), Staphylococcus epidermidis ATCC12228 (MIC=50 ?g/ml);##Gram-negative bacteria: Shigella dysenteriae ATCC9752 (MIC=50 ?g/ml), Escherichia coli KCTC2433 (MIC=60 ?g/ml), Klebsiella pneumoniae ATCC10031 (MIC=50 ?g/ml);##Yeast: Candida albicans ATCC36232 (MIC=50 ?g/ml)."	[Ref:17698251] It has 17.84% hemolytic activity at 100 ¦Ìg/ml against human red blood cells	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	No cytotoxicity information found	Not found	17698251	Peptides 2007; 28: 1532-1539. 	"Kim SS, Shim MS, Chung J, Lim DY, Lee BJ."	Purification and characterization of antimicrobial peptides from the skin secretion of Rana dybowskii.
DRAMP01253	FLPLLLAGLPLKLCFLFKKC	20	"Dybowskin-6 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana dybowskii (Korea brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Function: Dybowskin-6 has relatively greater hemolytic activity against human red blood cells (hRBCs).	"Gram-positive bacteria: Micrococcus luteus ATCC4698 (MIC=6.25 ?g/ml), Staphylococcus aureus KCTC3881 (MIC=12.5 ?g/ml), Bacillus subtilis ATCC6633 (MIC=50 ?g/ml), Staphylococcus epidermidis ATCC12228 (MIC=50 ?g/ml).##Yeast: Candida albicans (MIC=50 ?g/ml)."	[Ref:17698251] It has 59.39% hemolytic activity at 100 ¦Ìg/ml against huamn red blood cells	Cyclic	Free	Cyclization (Cys14 and Cys20)	Disulfide bond between Cys14 and Cys20.	L	No cytotoxicity information found	[Ref:17698251]59.39% hemolytic activity at 100 ¦Ìg/ml against huamn red blood cells	17698251	Peptides. 2007 Aug;28(8):1532-1539.	"Kim SS, Shim MS, Chung J, Lim DY, Lee BJ."	Purification and characterization of antimicrobial peptides from the skin secretion of Rana dybowskii.
DRAMP01257	GLWSKIKAAGKEAAKAAAKAAGKAALNAVSEAV	33	"Dermadistinctin-K (DD K; Frogs, amphibians, animals)"	P83638	Not found	Not found	Phyllomedusa distincta (Monkey frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal"	Protein level	Alpha helix	Not found	"2K9B, 2JX6 resolved by NMR."	"Function: Also has antiprotozoal activity against Trypanosoma cruzi. Decreases viability of murine peritoneal cells. Fuses to, and disrupts liposomes.
Tissue specificity: Expressed by the skin glands."	"Gram-positive bacteria: Staphylococcus aureus (MIC=4.7 ?M), Enterococcus faecalis (MIC>19 ?M);Gram-negative bacteria: Pseudomonas aeruginosa (MIC=2.4 ?M), Escherichia coli (MIC=0.6 ?M).##Fungi: Candida tropicalis (MIC=10.1 ?M), Candida guilliermondii (MIC=20.3 ?M), Candida albicans (MIC=20.3 ?M), Candida albicans ATCC 1023 (MIC=10.1 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	Free	L	[Ref.10477123]No cytotoxicity information found	liposomes	10477123	Peptides. 1999;20(6):679-686.	"Batista CV, da Silva LR, Sebben A, Scaloni A, Ferrara L, Paiva GR, Olamendi-Portugal T, Possani LD, Bloch C Jr."	Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta.
DRAMP01258	ALWKTLLKNVGKAAGKAALNAVTDMVNQ	28	"Dermadistinctin-L (DD L; Frogs, amphibians, animals)"	P83639	Not found	Not found	Phyllomedusa distincta (Monkey frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal"	Protein level	Alpha helix	Not found	None	"Function: Also has antiprotozoal activity against Trypanosoma cruzi. Decreases viability of murine peritoneal cells. Fuses to, and disrupts liposomes. Show little hemolytic activity against human red blood cells.
Tissue specificity: Expressed by the skin glands."	"[Ref.10477123]Gram-positive bacteria: Staphylococcus aureus (MIC=1.3 ?M), Enterococcus faecalis (MIC=10 ?M);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=40 ?M), Escherichia coli (MIC=2.5 ?M);##[Ref.17442605]Fungi: Candida tropicalis (MIC=10.9 ?M), Candida guilliermondii (MIC=21.8 ?M), Candida albicans (MIC=21.8 ?M), Candida albicans ATCC 1023 (MIC=10.9 ?M)."	[Ref:10477123]Show some hemolytic starting at 12.5 ¦ÌM against human blood	Linear	Free	Free	Free	L	[Ref.10477123]No cytotoxicity information found	liposomes	10477123##12379643##17409003##17442605	Peptides. 1999;20(6):679-686.##J Biol Chem. 2002 Dec 20;277(51):49332-49340.##Comp Biochem Physiol A Mol Integr Physiol. 2008 Nov;151(3):329-335.##Comp Biochem Physiol A Mol Integr Physiol. 2008 Nov;151(3):336-343.	"Batista CV, da Silva LR, Sebben A, Scaloni A, Ferrara L, Paiva GR, Olamendi-Portugal T, Possani LD, Bloch C Jr.##Brand GD, Leite JR, Silva LP, Albuquerque S, Prates MV, Azevedo RB, Carregaro V, Silva JS, S?? VC, Brand??o RA, Bloch C Jr.##Silva LP, Leite JR, Brand GD, Regis WB, Tedesco AC, Azevedo RB, Freitas SM, Bloch C Jr.##Leite JR, Brand GD, Silva LP, K??ckelhaus SA, Bento WR, Ara??jo AL, Martins GR, Lazzari AM, Bloch C Jr."	"Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta.##Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta. Anti-Trypanosoma cruzi activity without cytotoxicity to mammalian cells.##Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta: liposomes fusion and/or lysis investigated by fluorescence and atomic force microscopy.##Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta: Secondary structure, antimicrobial activity, and mammalian cell toxicity."
DRAMP01288	FLSLIPHIVSGVASIAKHF	19	"Phylloseptin-1 (PSN-1; Frogs, amphibians, animals)"	E3PQH3	Not found	PSN-1	Phyllomedusa sauvagei (Sauvage's leaf frog)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	Function: PSN-1 displayed broad-spectrum activity against a range of planktonic organisms.	"S. aureus (MIC=5 ?M), Escherichia coli and Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Amidation	Free	L	[Ref.20451254]No cytotoxicity information found	Not found	20451254	Mol Immunol. 2010 Jul;47(11-12):2030-2037.	"Zhang R, Zhou M, Wang L, McGrath S, Chen T, Chen X, Shaw C."	Phylloseptin-1 (PSN-1) from Phyllomedusa sauvagei skin secretion: a novel broad-spectrum antimicrobial peptide with antibiofilm activity.
DRAMP01301	FLSLIPHAINAVSAIAKHN	19	"Phylloseptin-1 (PS-1; Frogs, amphibians, animals)"	P84566	Not found	psn1	Phyllomedusa hypochondrialis (Orange-legged leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal"	Protein level	Alpha helix (1 helices; 14 residues)	The antimicrobial phylloseptin peptides adopt alpha-helical conformations in membrane environments which are stabilized by electrostatic interactions of the helix dipole as well as other contributions such hydrophobic and capping interactions.(Ref.2)	2JQ0 resolved by NMR.	"Function: Atomic force microscopy experiments indicated that the bacteriolytic properties of these peptides might be related to their disruptive action on the cell membrane. PS-1 did not exhibit significant hemolytic activity on human erythrocytes.
Tissue specificity: Expressed by the skin glands.
PTM: C-terminal amidation."	"[Ref.15752569]Gram-positive bacteria: Staphylococcus aureus (MIC=7.9 ?M), Enterococcus faecalis (MIC=4.0 ?M);##Gram-negative bacteria: Escherichia coli (MIC=7.9 ?M), Psecdomonas aeruginosa (MIC=4 ?M), Psecdomonas aeruginosa wt (MIC=3 ?M)."	"[Ref:15752569]0.3% hemolytic activity at 4 ¦ÌM, 0.57% hemolytic activity at 8 ¦ÌM, 0.6% hemolytic activity at 16 ¦ÌM, 0.98% hemolytic activity at 32 ¦ÌM, 1.98% hemolytic activity at 64 ¦ÌM against human red blood cells"	Linear 	Free	Amidation	Free	L	[REf.15752569]No cytotoxicity information found##[Ref.18656510]No cytotoxicity information found	Cell membrane	15752569##18656510	Peptides. 2005 Apr;26(4):565-573.##Peptides. 2008 Oct;29(10):1633-1644. 	"Leite JR, Silva LP, Rodrigues MI, Prates MV, Brand GD, Lacava BM, Azevedo RB, Bocca AL, Albuquerque S, Bloch C Jr.##Resende JM, Moraes CM, Prates MV, Cesar A, Almeida FC, Mundim NC, Valente AP, Bemquerer MP, Pil??-Veloso D, Bechinger B."	"Phylloseptins: a novel class of anti-bacterial and anti-protozoan peptides from the Phyllomedusa genus.##Solution NMR structures of the antimicrobial peptides phylloseptin-1, -2, and -3 and biological activity: the role of charges and hydrogen bonding interactions in stabilizing helix conformations."
DRAMP01302	FLSLIPHAINAVSTLVHHF	19	"Phylloseptin-2 (PS-2; Frogs, amphibians, animals)"	"P85881, P84567, Q0VZ43"	Not found	psn2	Phyllomedusa hypochondrialis (Orange-legged leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix (1 helices; 14 residues)	The antimicrobial phylloseptin peptides adopt alpha-helical conformations in membrane environments which are stabilized by electrostatic interactions of the helix dipole as well as other contributions such hydrophobic and capping interactions.(Ref.2)	2JPY resolved by NMR.	"Function: Has antimicrobial activity. PS-2 did not exhibit significant hemolytic activity on human erythrocytes.
Tissue specificity: Expressed by the skin glands.
PTM: C-terminal amidation."	"[Ref.18656510][ATCC Strains]: Gram-positive bacteria: S. aureus (MIC=15.1 ?M);##Gram-negative bacteria: Escherichia coli (MIC=60.4 ?M), Klebsiella pneumoniae (MIC=60.4 ?M), Pseudomonas aeruginosa (MIC=60.4 ?M);##[Wild Type]: Gram-positive bacteria: S. aureus (MIC=7.6 ?M), S. agalactiae (MIC=1.9 ?M);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=60.4 ?M), A. calcoaceticus (MIC=3.7 ?M);##Fungi: Candida albicans (MIC=15.1 ?M)."	"[Ref:15752569]0.1% hemolytic activity at 4 ¦ÌM, 0.28% hemolytic activity at 4 ¦ÌM, 0.7% hemolytic activity at 8 ¦ÌM, 0.8% hemolytic activity at 16 ¦ÌM, 1.05% hemolytic activity at 32 ¦ÌM, 2.05% hemolytic activity at 64 ¦ÌM against human red blood cells"	Linear 	Free	Amidation	Free	L	[REf.15752569]No cytotoxicity information found##[Ref.18656510]No cytotoxicity information found	Cell membrane	15752569##18656510	Peptides. 2005 Apr;26(4):565-573.##Peptides. 2008 Oct;29(10):1633-1644. 	"Leite JR, Silva LP, Rodrigues MI, Prates MV, Brand GD, Lacava BM, Azevedo RB, Bocca AL, Albuquerque S, Bloch C Jr.##Resende JM, Moraes CM, Prates MV, Cesar A, Almeida FC, Mundim NC, Valente AP, Bemquerer MP, Pil??-Veloso D, Bechinger B."	"Phylloseptins: a novel class of anti-bacterial and anti-protozoan peptides from the Phyllomedusa genus.##Solution NMR structures of the antimicrobial peptides phylloseptin-1, -2, and -3 and biological activity: the role of charges and hydrogen bonding interactions in stabilizing helix conformations."
DRAMP01303	FLSLIPHAINAVSALANHG	19	"Phylloseptin-3 (PS-3; Frogs, amphibians, animals)"	P84568	Not found	psn3	Phyllomedusa hypochondrialis (Orange-legged leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix (1 helices; 11 residues)	The antimicrobial phylloseptin peptides adopt alpha-helical conformations in membrane environments which are stabilized by electrostatic interactions of the helix dipole as well as other contributions such hydrophobic and capping interactions.(Ref.2)	2JQ1 resolved by NMR.	"Function: Has antimicrobial activity (By similarity).
Tissue specificity: Expressed by the skin glands.
PTM: C-terminal amidation."	"[ATCC Strains]: Gram-positive bacteria: S. aureus (MIC=32.9 ?M);##Gram-negative bacteria: Escherichia coli (MIC=65.6 ?M), Klebsiella pneumoniae (MIC=65.6 ?M), Pseudomonas aeruginosa (MIC=65.6 ?M). NOTE: Initial inoculum of 108 cells/Ml.##[Wild Type]: Gram-positive bacteria: S. aureus (MIC=8.2 ?M), S. agalactiae (MIC=4.1 ?M);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=32.8 ?M), A. calcoaceticus (MIC=4.1 ?M).##Fungi: Candida albicans (MIC=8.2 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Amidation	Free	L	[Ref.15752569]No cytotoxicity information found##[Ref.18656510]No cytotoxicity information found	Cell membrane	15752569##18656510	Peptides. 2005 Apr;26(4):565-573.##Peptides. 2008 Oct;29(10):1633-1644. 	"Leite JR, Silva LP, Rodrigues MI, Prates MV, Brand GD, Lacava BM, Azevedo RB, Bocca AL, Albuquerque S, Bloch C Jr.##Resende JM, Moraes CM, Prates MV, Cesar A, Almeida FC, Mundim NC, Valente AP, Bemquerer MP, Pil??-Veloso D, Bechinger B."	"Phylloseptins: a novel class of anti-bacterial and anti-protozoan peptides from the Phyllomedusa genus.##Solution NMR structures of the antimicrobial peptides phylloseptin-1, -2, and -3 and biological activity: the role of charges and hydrogen bonding interactions in stabilizing helix conformations."
DRAMP01319	RRSRRGRGGGRRGGSGGRGGRGGGGRSGAGSSIAGVGSRGGGGGRHYA	48	"Cathelicidin-AL (Gly-rich; Frogs, amphibians, animals)"	No entry found	Not found	Not found	Amolops loloensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=6.25 ?g/ml), Staphylococcus aureus ATCC43300 (MIC=6.25 ?g/ml), Bacillus subtilis (MIC=100 ?g/ml);##Gram-negative bacteria: Escherichia coli ML-35P (MIC=25 ?g/ml), Psecdomonas aeruginosa PA01 (MIC=12.5 ?g/ml), Psecdomonas aeruginosa ATCC27853 (MIC=6.25 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=50 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Free	Free	L	[Ref.22009138]No cytotoxic against HUVEC or  RMMCs at the concentration of 0.4 mg/ml.	Not found	22009138	Amino Acids. 2012 Aug;43(2):677-685.	"Hao X, Yang H, Wei L, Yang S, Zhu W, Ma D, Yu H, Lai R."	Amphibian cathelicidin fills the evolutionary gap of cathelicidin in vertebrate.
DRAMP01339	FLPIVGKLLSGLSGLL	16	"Amolopin-2a (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Amolops loloensis (Rufous-spotted torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Staphylococcus aureus (MIC=2.00 ?g/ml), Bacillus dysenteriae (MIC=1.50 ?g/ml);##Gram-negative bacterium: Escherichia coli (MIC=3.00 ?g/ml).##Candida albicans (MIC=6.50 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.17000029]Display cytotoxicity against HepG2(IC50=77 mg/ml).	Not found	17000029	Peptides. 2006 Dec;27(12):3085-3091. 	"Lu Y, Li J, Yu H, Xu X, Liang J, Tian Y, Ma D, Lin G, Huang G, Lai R."	"Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis."
DRAMP01341	FLPLAVSLAANFLPKLFCKITKKC	24	"Amolopin-1b (Frogs, amphibians, animals)"	A0SN42	Not found	Not found	Amolops loloensis (Rufous-spotted torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Staphylococcus aureus (MIC=5.50 ?g/ml), Bacillus dysenteriae (MIC=2.20 ?g/ml);##Gram-negative bacterium: Escherichia coli (MIC=6.50 ?g/ml).##Yeast: Candida albicans (MIC=7.50 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization(Cys18 and Cys24)	Disulfide bridge between Cys18 and Cys24.	L	[Ref.17000029]Display cytotoxicity against HepG2(IC50=58 mg/ml).	Not found	17000029	Peptides. 2006 Dec;27(12):3085-3091. 	"Lu Y, Li J, Yu H, Xu X, Liang J, Tian Y, Ma D, Lin G, Huang G, Lai R."	"Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis."
DRAMP01346	VIGSILGALASGLPTLISWIKNR	23	"Prepromelittin-related peptide (Frogs, amphibians, animals)"	A7BJK5	Not found	prMRP	Rana sakuraii (Japanese brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	Gram-negative bacterium: Escherichia coli (MIC=25 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=6 ?M).##Yeast: Candida albicans (MIC=25 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.17174009]No cytotoxicity information found##[Ref.17826868]No cytotoxicity information found	Not found	17174009##17826868	Peptides. 2007;28(3):505-514.##Peptides. 2007 Oct;28(10):2061-2068.	"Suzuki H, Iwamuro S, Ohnuma A, Coquet L, Leprince J, Jouenne T, Vaudry H, Taylor CK, Abel PW, Conlon JM.##Suzuki H, Conlon JM, Iwamuro S."	Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii.##Evidence that the genes encoding the melittin-related peptides in the skins of the Japanese frogs Rana sakuraii and Rana tagoi are not orthologous to bee venom melittin genes: developmental- and tissue-dependent gene expression.
DRAMP01347	AIGSILGALAKGLPTLISWIKNR	23	"Prepromelittin-related peptide (Frogs, amphibians, animals)"	A7BJK6	Not found	prMRP	Rana tagoi (Tago frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Alpha helix	Not found	6dst resolved by NMR (related PDB_ID)	Function: Antibacterial activity against Gram-positive and Gram-negative bacteria. Antifungal activity against C. albicans.	"[Ref.12804591]Gram-positive bacterium: Staphylococcus aureus (MIC=3.5 ?M);##Gram-negative bacterium: Escherichia coli (MIC=20 ?M).##Yeast: Candida albicans (MIC=19 ?M).##EL4 T-lymphoma cells (MIC=14 ?M).##[Ref.27271216]Gram-positive bacteria : Staphylococcuss aureus (MIC=6.25 ¦ÌM), Staphylococcus epidermidis (MIC=3.13 ¦ÌM), Bacillus subtilis (MIC=3.13 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MIC=25 ¦ÌM), Pseudomonas aeruginosa (MIC=12.5 ¦ÌM), Klebsiella pneumoniae (MIC=12.5 ¦ÌM)"	[Ref.27271216] 100% hemolysis at 20 ¦ÌM against human red blood cells	Linear	Free	Amidation	Free	L	[Ref.12804591]Display cytotoxic against L929 fibroblasts(LC50=20 ¦ÌM);EL4 T-lymphoma cells(LC50=14 ¦ÌM).##[Ref.27271216]L929 cells:Cell viability is approximately 10% at the concentration of 6.25?¦ÌM.	Not found	12804591##17174009##27271216	Biochem Biophys Res Commun. 2003 Jun 27;306(2):496-500.##Peptides. 2007;28(3):505-514.##Sci Rep. 2016 Jun 8;6:27394.	"Conlon JM, Sonnevend A, Patel M, Camasamudram V, Nowotny N, Zilahi E, Iwamuro S, Nielsen PF, P¨¢l T##Suzuki H, Iwamuro S, Ohnuma A, Coquet L, Leprince J, Jouenne T, Vaudry H, Taylor CK, Abel PW, Conlon JM.##Shi-KunZhang, Jin-wen Song, FengGong, Su-Bo Li, Hong-Yu Chang, Hui-MinXie, Hong-WeiGao, Ying-XiaTan & Shou-Ping Ji"	"A melittin-related peptide from the skin of the Japanese frog, Rana tagoi, with antimicrobial and cytolytic properties##Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii##Design of an ¦Á-helical antimicrobial peptide with improved cell selective and potent anti-biofilm activity"
DRAMP01350	FCTMIPIPRCY	11	"Tigerinin-1 (Frogs, amphibians, animals)"	P82651	Not found	Not found	Rana tigerina (Indian bull frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Bacillus subtilis (MIC=30 ?g/ml), Staphylococcus aureus ATCC 8530 (MIC=30 ?g/ml), Micrococcus luteus MT 166 (MIC=20 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=40 ?g/ml), Pseudomonas putida NCIM 2102 (MIC=40 ?g/ml).##Fungi: Saccharomyces cerevisiae ATCC 8530 (MIC=80 ?g/ml)."	[Ref.11031261] It exhibits no hemolytic activity up to a concentration of 200 ¦Ìg/ml against rat erythrocytes.	Cyclic	Free	Amidation	Disulfide bond between Cys2 and Cys10.	L	No cytotoxicity information found	Cell membrane	11031261	J Biol Chem. 2001 Jan 26;276(4):2701-2707. 	"Sai KP, Jagannadham MV, Vairamani M, Raju NP, Devi AS, Nagaraj R, Sitaram N."	Tigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
DRAMP01351	RVCFAIPLPICH	12	"Tigerinin-2 (Frogs, amphibians, animals)"	P82652	Not found	Not found	Rana tigerina (Indian bull frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Bacillus subtilis (MIC=20 ?g/ml), Staphylococcus aureus ATCC 8530 (MIC=40 ?g/ml), Micrococcus luteus MT 166 (MIC=20 ?g/ml).##Gram-negative bacteria: Pseudomonas putida NCIM 2102 (MIC=50 ?g/ml), Escherichia coli (MIC=50 ?g/ml).##Fungi: Saccharomyces cerevisiae ATCC 8530 (MIC=100 ?g/ml)."	[Ref.11031261] It exhibits no hemolytic activity up to a concentration of 200 ¦Ìg/ml against rat erythrocytes.	Cyclic	Free	Amidation	Disulfide bond between Cys3 and Cys11.	L	No cytotoxicity information found	Cell membrane	11031261	J Biol Chem. 2001 Jan 26;276(4):2701-2707. 	"Sai KP, Jagannadham MV, Vairamani M, Raju NP, Devi AS, Nagaraj R, Sitaram N."	Tigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
DRAMP01352	RVCYAIPLPICY	12	"Tigerinin-3 (Frogs, amphibians, animals)"	P82653	Not found	Not found	Rana tigerina (Indian bull frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Bacillus subtilis (MIC=30 ?g/ml), Staphylococcus aureus ATCC 8530 (MIC=30 ?g/ml), Micrococcus luteus MT 166 (MIC=30 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=40 ?g/ml), Pseudomonas putida NCIM 2102 (MIC=40 ?g/ml).##Fungi: Saccharomyces cerevisiae ATCC 8530 (MIC=80 ?g/ml)."	[Ref.11031261] It exhibits no hemolytic activity up to a concentration of 200 ¦Ìg/ml against rat erythrocytes.	Cyclic	Free	Amidation	Disulfide bond between Cys3 and Cys11.	L	No cytotoxicity information found	Cell membrane	11031261	J Biol Chem. 2001 Jan 26;276(4):2701-2707. 	"Sai KP, Jagannadham MV, Vairamani M, Raju NP, Devi AS, Nagaraj R, Sitaram N."	Tigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
DRAMP01353	RVCYAIPLPIC	11	"Tigerinin-4 (Frogs, amphibians, animals)"	P82654	Not found	Not found	Rana tigerina (Indian bull frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Beta strand-turn	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacterium: Staphylococcus aureus ATCC 8530 (MIC=50 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=60 ?g/ml), Pseudomonas putida NCIM 2102 (MIC=60 ?g/ml).##Fungi: Saccharomyces cerevisiae ATCC 8530 (MIC=100 ?g/ml)."	[Ref.11031261] It exhibits no hemolytic activity up to a concentration of 200 ¦Ìg/ml against rat erythrocytes.	Cyclic	Free	Amidation;Cyclization (Cys3 and Cys11)	Disulfide bond between Cys3 and Cys11.	L	No cytotoxicity information found	Cell membrane	11031261	J Biol Chem. 2001 Jan 26;276(4):2701-2707. 	"Sai KP, Jagannadham MV, Vairamani M, Raju NP, Devi AS, Nagaraj R, Sitaram N."	Tigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
DRAMP01354	LVRGCWTKSYPPKPCFVR	18	"Peptide leucine arginine (pLR; Frogs, amphibians, animals)"	"Q90WP7, P82110"	Not found	Not found	Rana pipiens (Northern leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: Mast cell degranulating peptide. Antiproliferative activity against human breast and ovarian tumor cell lines in vitro. Inhibits granulopoiesis in rat in vitro. Causes histamine release from rat peritoneal mast cells in vitro. Has antibacterial activity against Gram-positive bacteria: B.megaterium Bm11, S. lentus and M.luteus, and antifungal activity against C.tropicalis, C.guiller-mondii and P.nicotianae spores. Has hemolytic activity. The mature peptide inserts into the hydrophobic core of the bacterial cell membrane and increases permeability without disrupting membrane integrity. Probably binds to the outer membrane surface before aggregating to form transmembrane pores."	"[Ref.11099505]Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=20 ?M), Staphylococcus lentus (MIC=50 ?M), Micrococcus luteus (MIC=10 ?M);##Fungi: Candida tropicalis (MIC=11 ?M), Candida guillermondii (MIC=6.6 ?M), Phytophthora nicotianae spores (MIC=75 ?M)."	[Ref:11099505] It has 2.5% hemolytic activity at 100 ¦ÌM against human red blood	Cyclic	Free	Free	Disulfide bond between Cys5 and Cys15.	L	No cytotoxicity information found	Not found	11099505	J. Biol. Chem. 2001;276:10145-10152.	"Salmon A.L, Cross L.J.M, Irvine A.E, Lappin T.R.J, Dathe M, Krause G, Canning P, Thim L, Beyermann M, Rothemund S, Bienert M, Shaw C."	"Peptide leucine arginine, a potent immunomodulatory peptide, isolated and structurally characterized from the skin of the Northern Leopard frog, Rana pipiens."
DRAMP01355	FLGGLIKIVPAMICAVTKKC	20	"Ranalexin (Frogs, amphibians, animals)"	P39084	Not found	Not found	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Potent microbicidal activity, active against S.aureus and E.coli. It acts as well as a membrane-disruptive agent at higher concentrations.
Tissue specificity: Expressed by the skin dorsal glands.
Developmental stage: Expression starts at metamorphosis and continues into adulthood.
PTM: Contains one disulfide bond 14-20."	"Gram-positive bacterium: Staphylococcus aureus (MIC=4 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=32 ?g/ml), Pseudomonas aeruginosa (MIC=128 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys14 and Cys20)	Disulfide bond between Cys14 and Cys20.	L	No cytotoxicity information found	Not found	8144672##9578480	J Biol Chem. 1994 Apr 8;269(14):10849-10855.##Eur J Biochem. 1998 Apr 1;253(1):221-228.	"Clark DP, Durell S, Maloy WL, Zasloff M.##Vignal E, Chavanieu A, Roch P, Chiche L, Grassy G, Calas B, Aumelas A."	"Ranalexin. A novel antimicrobial peptide from bullfrog (Rana catesbeiana) skin, structurally related to the bacterial antibiotic, polymyxin.##Solution structure of the antimicrobial peptide ranalexin and a study of its interaction with perdeuterated dodecylphosphocholine micelles."
DRAMP01364	GLFGVLAKVAAHVVPAIAEHF	21	"Maculatin-1.1 (Frogs, amphibians, animals)"	P82066	Not found	Not found	Litoria genimaculata (Green-eyed tree frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral"	Protein level	Alpha helix	Not found	None	"Function: Maculatin-1.1 shows significant antibacterial activity against Gram-positive bacteria, less against Gram-negative bacteria.
Tissue specificity: Expressed by the skin dorsal glands.
PTM: C-terminal amidation."	"[Ref.15203252]Gram-positive bacteria: Bacillus cereus (MIC=25 ?g/ml), Bacillus cereus (MIC=3 ?g/ml), Listeria innocua (MIC=100 ?g/ml), Micrococcus luteus (MIC=12 ?g/ml), Staphylococcus aureus (MIC=6 ?g/ml), Staphylococcus epidermidis (MIC=12 ?g/ml), Streptococcus uberis (MIC=3 ?g/ml);##Gram-negative bacterium: Pasteurella multocida (MIC=50 ?g/ml). ##[Ref.16140737]Virus:HIV:inhibit 50% of PBS-treated HIV infection of T cells(IC50=11.3 ¦ÌM)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	No cytotoxicity information found in the reference(s) presented	Not found	16140737##9620615##15203252	J Virol. 2005 Sep;79(18):11598-606. ##J Pept Sci. 1998 Apr;4(2):111-115.##Peptides. 2004; 25: 1035-1054.	"VanCompernolle SE, Taylor RJ, Oswald-Richter K, Jiang J, Youree BE, Bowie JH, Tyler MJ, Conlon JM, Wade D, Aiken C, Dermody TS, KewalRamani VN, Rollins-Smith LA, Unutmaz D. ##Rozek T, Waugh RJ, Steinborner ST, Bowie JH, Tyler MJ, Wallace JC.##Apponyi MA, Pukala TL, Brinkworth CS, Maselli VM, Bowie JH, Tyler MJ, Booker GW, Wallace JC, Carver JA, Separovic F, Doyle J, Llewellyn LE."	"Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells.##The maculatin peptides from the skin glands of the tree frog Litoria genimaculata: a comparison of the structures and antibacterial activities of maculatin 1.1 and caerin 1.1.##Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance."
DRAMP01370	MLCKLSMFGAVLGVPACAIDCLPMGKTGGSCEGGVCGCRKLTFKILWDKKFG	52	"Oh-defensin (O. hainana defensin; spiders, animals)"	No entry found	Not found	Not found	Ornithoctonus hainana (Venoms)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial and antifungal activities.	"Gram-positive bacteria: Staphylococcus aureus (MIC=1.25 ?g/ml), Bacillus cereus (MIC=25 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=1.25 ?g/ml), Bacillus dysenteriae (MIC=1.25 ?g/ml), Pseudomonas aeruginosa (MIC=5 ?g/ml).##Yeast: Candida albicans (MIC=1.25 ?g/ml)."	"[Ref.21538709] It has little hemolytic activity, inducing 7% hemolysis at the concentration up to 200 ?g/ml (about 36 ?M)."	Cyclic	Free	Free	Has three disulfide bonds	L	No cytotoxicity information found	Not found	21538709	J Pept Sci. 2011 Jul;17(7):540-544. 	"Zhao H, Kong Y, Wang H, Yan T, Feng F, Bian J, Yang Y, Yu H."	"A defensin-like antimicrobial peptide from the venoms of spider, Ornithoctonus hainana."
DRAMP01371	GLLSGILGAGKHIVCGLTGCAKA	23	"Odorranain-NR (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Combine helix and strand structure	"Odorranain-NR has a large proportion of beta-sheet. In Tris HCl + SDS, odorranain-NR has a major conformation of beta-sheet (79.2%) and a minor conformation of beta-turn (1.3%). In Tris HCl, the beta-sheet has been decreased to 57.1% and the beta-turn has been increased to 10.5%. The beta-sheet has been decreased to 39.8% in water."	None	"Function: Odorranain-NR exhibits antimicrobial activity against the tested strains except E. coli ATCC25922. Odorranain-NR has little hemolytic activity on red blood cells even with peptide concentration up to 100 mg/ml.
PTM: Odorranain-NR has an intramolecular disulfide-bridged hexapeptide segment, which is a new type of disulfide-bridge motif in amphibian antimicrobial peptides."	"[Ref.18282640]Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=9.375 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC>100 ?g/ml), Bacillus dysenteriae (MIC=37.5 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=18.75 ?g/ml)."	[Ref:18282640] It has little hemolytic activity at 100 ¦Ìg/ml against rabbit red blood cells	Cyclic	Free	Free	Disulfide bond between Cys15 and Cys20.	L	No cytotoxicity information found	Not found	18282640	Peptides. 2008 Apr;29(4):529-535. 	Che Q et al Lai R.	A novel antimicrobial peptide from amphibian skin secretions of Odorrana grahami.
DRAMP02244	GLFLDTLKGAAKDVAGKLLEGLKCKIAGCKP	31	"Ranatuerin-2Ca (Ranatuerin 2Ca; Frogs, amphibians, animals)"	P82878	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Rana clamitans (Green frog) (Lithobates clamitans)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide has defense response to Gram-positive bacterium, defense response to Gram-negative bacterium, male-specific defense response to bacterium, antibacterial humoral response, antibacterial humoral response,  induced systemic resistance, antifungal innate immune response, antifungal humoral response, defense response to fungus (incompatible interaction) in GO analysis.
Tissue specificity: Expressed by the skin glands.
PTM: Disulfide bond at position 24 and 29."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bond between Cys24 and Cys29.	L	No cytotoxicity information found	Not found	10822101	Peptides. 2000 Apr;21(4):469-476.	"Halverson T, Basir YJ, Knoop FC, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin of the North American green frog Rana clamitans.
DRAMP01357	FLGGLMKAFPAIICAVTKKC	20	"Ranalexin-1Cb (Ranatuerin 1Cb; Frogs, amphibians, animals)"	P82877	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Rana clamitans (Green frog) (Lithobates clamitans)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide has defense response to Gram-positive bacterium, defense response to Gram-negative bacterium, male-specific defense response to bacterium, antibacterial humoral response, antibacterial humoral response,  induced systemic resistance, antifungal innate immune response, antifungal humoral response, defense response to fungus (incompatible interaction) in GO analysis.
Tissue specificity: Expressed by the skin glands."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys14 and Cys20)	Disulfide bond between Cys14 and Cys20.	L	No cytotoxicity information found	Not found	10822101	Peptides. 2000 Apr;21(4):469-476.	"Halverson T, Basir YJ, Knoop FC, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin of the North American green frog Rana clamitans.
DRAMP02246	SMLSVLKNLGKVGLGLVACKINKQC	25	"Ranatuerin-1C (Ranatuerin 1C; Frogs, amphibians, animals)"	P82875	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Rana clamitans (Green frog) (Lithobates clamitans)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. 
Tissue specificity: Expressed by the skin glands."	[Ref.10822101] Gram-positive bacterium: Staphylococcus aureus (MIC=55 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=1.5 ¦ÌM).##Yeast: Candida albicans (MIC=58 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys19 and Cys25)	Disulfide bond between Cys19 and Cys25.	L	No cytotoxicity information found	Not found	10822101	Peptides. 2000 Apr;21(4):469-476.	"Halverson T, Basir YJ, Knoop FC, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin of the North American green frog Rana clamitans.
DRAMP01394	GLLRASSVWGRKYYVDLAGCAKA	23	"Odorranain-W2 (Frogs, amphibians, animals)"	A7YL71	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Shows antibacterial and antifungal activities.	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 ?g/ml), Bacillus dysenteriae (MIC=30 ?g/ml), Helicobacter pylori NCTC 11637 (MIC=20 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=5 ?g/ml).##Yeast: Candida albicans ATCC 2002 (MIC=25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Free	Free	L	[Ref.17698252]No cytotoxicity information found	Not found	17698252	Peptides. 2007 Aug;28(8):1527-1531. 	"Chen L, Li Y, Li J, Xu X, Lai R, Zou Q."	An antimicrobial peptide with antimicrobial activity against Helicobacter pylori.
DRAMP01395	VVKCSYRLGSPDSQCN	16	"Odorranain-A-OA1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Weakly active against bacteria and fungi.	"[Ref.22029824]Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=35.2 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=35.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=17.6 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=17.6 ?g/ml)."	[Ref:22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Free	Disulfide bond between Cys4 and Cys15.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01396	GFMDTAKNVAKNMAGNLLDNLKCKITKAC	29	"Odorranain-F-OA1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=10 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=2.5 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=2.5 ?g/ml)."	[Ref:22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys23 and Cys29)	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01397	GFMDTAKNVAKNMAVTLLDNLKCKITKAC	29	"Odorranain-F-OA2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Weakly active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=7.5 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=7.5 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=3.8 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=3.8 ?g/ml)."	[Ref:22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys23 and Cys29)	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01398	GFMDTAKNVAKNEAGNLLDNLKCKITKAC	29	"Odorranain-F-OA3 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Weakly active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=12.6 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=12.6 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6.3 ?g/ml)£»##Yeast: Candida albicans ATCC 2002 (MIC=6.3 ?g/ml)."	[Ref:22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys23 and Cys29)	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01399	GFMATAKNVAKNMDVTLLDNLKCKITKAC	29	"Odorranain-F-OA4 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Weakly active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=8.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=4.1 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=4.1 ?g/ml)£»##Yeast: Candida albicans ATCC 2002 (MIC=4.1 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys23 and Cys29)	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP18395	FFGHLFRGIINVGKHIHGLLSG	22	"moroPC-NH2 (moronecidin-like peptide; fish, animals)"	No entry found	Not found	Not found	Parachaenichthys charcoti	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against Gram- E. cloacae ATCC 13047 (MIC 25 uM), S. sonnei (ATCC 29930) (MIC 5 uM), Psychrobacter sp. (PAMC 25501) (MIC 2.5 uM), E. coli DH5alpha (MIC 5 uM), Gram+ E. faecalis (ATCC 29212) (MIC 25 uM), S. pyogenes (ATCC 19615) (MIC 2.5 uM), S. aureus (ATCC 33591), L. monocytogenes (ATCC 15313) (MIC 5 uM), and yeast C. tropicalis (ATCC 20115) (MIC 5 uM). "	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.28122029]No cytotoxicity information found	Not found	28122029	PLoS One. 2017 Jan 25;12(1):e0170821.	"Shin SC, Ahn IH, Ahn DH, Lee YM, Lee J, Lee JH, Kim HW, Park H"	Characterization of Two Antimicrobial Peptides from Antarctic Fishes (Notothenia coriiceps and Parachaenichthys charcoti)
DRAMP01401	GFMNTAKNVAKNVAVTLLDNLKCKITGGC	29	"Odorranain-F-OW1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana wuchuanensis (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli (MIC=2 ?M), Pseudomonas aeruginosa (MIC=4 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=4 ?M).##Yeast: Candida albicans ATCC 2002 (MIC=2 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys23 and Cys29)	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01402	GLFTLIKGAYKLDAPTVACN	20	"Odorranain-J-OA1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Weakly active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=40.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=40.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=20.1 ?g/ml)£»##Yeast: Candida albicans ATCC 2002 (MIC=20.1 ?g/ml)."	[Ref:22029824]Not found	Linear	Free	Free	Free	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01403	GLFTLIKGAYKNDAPTVACN	20	"Odorranain-J-OA2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Weakly active against bacteria and fungi.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=40.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=40.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=20.1 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=20.1 ?g/ml)."	[Ref:22029824]Not found	Linear	Free	Free	Free	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01409	GILSGILGVGKKLVCGLSGLC	21	"Nigrocin-OR1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana rotodora (Chinese odorous frogs)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli (MIC=4 ?M), Pseudomonas aeruginosa (MIC=7 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=2 ?M).##Yeast: Candida albicans (MIC=4 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01410	GILSGILGVGKMLVCGLSGLC	21	"Nigrocin-OR2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana rotodora (Chinese odorous frogs)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3 ?M), Bacillus pyocyaneus CMCCB 10104 (MIC=5 ?M);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=3 ?M).##Yeast: Candida albicans ATCC 2002 (MIC=3 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01411	GILSGLLGVGKMLVCGLSGLC	21	"Nigrocin-OR3 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana rotodora (Chinese odorous frogs)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3 ?M), Bacillus pyocyaneus CMCCB 10104 (MIC=6 ?M);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6 ?M).##Yeast: Candida albicans ATCC 2002 (MIC=3 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01414	GIFSTVFKAGKGIVCGLTGLC	21	"Nigrocin-2ISa (Frogs, amphibians, animals)"	F1T156	Not found	Not found	Odorrana ishikawae (Ishikawa's frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-negative bacterium: Escherichia coli (MIC=25 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.1 ?M), Staphylococcus aureus (MRSA) (MIC=12.5 ?M), Bacillus subtilis (MIC=12.5 ?M).##Yeast: Candida albicans (MIC=50 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	[Ref.21193000]No cytotoxicity information found	Not found	21193000	Peptides. 2011 Apr;32(4):670-676. 	"Iwakoshi-Ukena E, Ukena K, Okimoto A, Soga M, Okada G, Sano N, Fujii T, Sugawara Y, Sumida M."	Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae.
DRAMP01415	GILGTVFKAGKGIVCGLTGLC	21	"Nigrocin-2ISb (Frogs, amphibians, animals)"	F1T157	Not found	Not found	Odorrana ishikawae (Ishikawa's frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-negative bacterium: Escherichia coli (MIC=50 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.1 ?M), Staphylococcus aureus (MRSA) (MIC=12.5 ?M), Bacillus subtilis (MIC=12.5 ?M).##Yeast: Candida albicans (MIC=50 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	21193000	Peptides. 2011 Apr;32(4):670-676. 	"Iwakoshi-Ukena E, Ukena K, Okimoto A, Soga M, Okada G, Sano N, Fujii T, Sugawara Y, Sumida M."	Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae.
DRAMP01416	GILSTVFKAGKGIVCGLSGLC	21	"Nigrocin-2ISc (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana ishikawae (Ishikawa's frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: Escherichia coli (MIC=50 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=3 ?M).##Yeast: Candida albicans (MIC=100 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	21867685	Biochem Biophys Res Commun. 2011 Sep 9;412(4):673-677. 	"Iwakoshi-Ukena E, Soga M, Okada G, Fujii T, Sumida M, Ukena K."	Characterization of novel antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae by shotgun cDNA cloning.
DRAMP01418	GLFGKILGVGKKVLCGLSGMC	21	"Nigrocin-2GRb (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana grahami (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial against the Gram-negative bacterium E. coli and the Gram-positive bacterium S. aureus. Also has a weak hemolytic activity against human erythrocytes.	[Ref.16621155]Gram-positive bacterium: Staphylococcus aureus (MIC=12.5 ?M);##Gram-negative bacterium: Escherichia coli (MIC=3 ?M);##Yeast: Candida albicans (MIC=50 ?M).	[Ref:16621155] LC50=40 ¦ÌM against human erythrocytes	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	16621155	Peptides. 2006 Sep;27(9):2111-2117.	"Conlon JM, Al-Ghaferi N, Abraham B, Jiansheng H, Cosette P, Leprince J, Jouenne T, Vaudry H."	"Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami."
DRAMP01420	GLLSGILGAGKHIICGLSGLC	21	"Nigrocin-OG4 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-negative bacterium: Escherichia coli (MIC>100 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC>100 ?g/ml), Bacillus subtilis (MIC>100 ?g/ml).##Yeast: Candida albicans (MIC=1.10 ?g/ml)."	"[Ref.17272268] RCH=65.5 ¡À 7.7% against rabbit red blood cells at 50 ¦Ìg/ml. RCH, red cell hemolysis."	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01421	GLLSGILGAGKQKVCGLSGLC	21	"Nigrocin-OG5 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-negative bacterium: Escherichia coli (MIC=9.37 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=18.75 ?g/ml), Bacillus subtilis (MIC=37.50 ?g/ml).##Yeast: Candida albicans (MIC=4.68 ?g/ml)."	"[Ref.17272268] RCH=87.2 ¡À 2.6% against rabbit red blood cells at 50 ¦Ìg/ml. RCH, red cell hemolysis."	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01422	GLLSGVLGVGKKVLCGLSGLC	21	"Nigrosin-OG21 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-negative bacterium: Escherichia coli (MIC=4.68 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=9.37 ?g/ml), Bacillus subtilis (MIC=18.75 ?g/ml).##Yeast: Candida albicans (MIC=4.68 ?g/ml)."	"[Ref.17272268] RCH=100% against rabbit red blood cells at 50 ¦Ìg/ml. RCH, red cell hemolysis."	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01423	GLLSGILGAGKHIVCGLSGLR	21	"Nigrosin-OG13 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-negative bacterium: Escherichia coli (MIC=4.68 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=9.37 ?g/ml), Bacillus subtilis (MIC=18.75 ?g/ml).##Yeast: Candida albicans (MIC=1.10 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	Free	L	[Ref.17272268]No cytotoxicity information found	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01426	GLLSGVLGVGKKIVCGLSGLC	21	"Nigrocin-1-OA1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"[Ref.22029824]Gram-negative bacteria: Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=10.4 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=10.4 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=5.2 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01427	GIFGKILGVGKKTLCELSGMC	21	"Nigrocin-1-OA2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.3 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=6.3 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6.3 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=3.2 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01428	GIFLKVLGVGKKVLCGVSGLC	21	"Nigrocin-1-OA3 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=10.8 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=21.6 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=5.4 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=10.8 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01429	GLISGILGVGKKLVCGLSGLC	21	"Nigrocin-1-OR1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=11.5 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=23 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=5.8 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=11.5 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01430	GLISGILGVGKMLVCGLSGLC	21	"Nigrocin-1-OR2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=8.6 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=17.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=8.6 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=8.6 ?g/ml)"	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01431	GLISGLLGVGKMLVCGLSGLC	21	"Nigrocin-1-OR3 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=10.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=20.4 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=20.4 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=10.2 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01432	GILGNIVGMGKKIVCGLSGLC	21	"Nigrocin-1-OW2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=12.4 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6.2 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=3.1 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01433	GILGNIVGMGKKVVCGLSGLC	21	"Nigrocin-1-OW3 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=11.3 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=22.6 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=11.3 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=6.7 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01434	GILSGVLGMGKKIVCGLRGLC	21	"Nigrocin-1-OW4 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=7.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=14.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=3.6 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=7.2 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01435	GILGNIVGMGKQVVCGLSGLC	21	"Nigrocin-1-OW5 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.1 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=10.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=5.1 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=5.1 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01436	GILSGVLGMGKKIVCGLSGLC	21	"Nigrocin-1-OW1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=4.4 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=8.8 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=8.8 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=4.4 ?g/ml)."	[Ref:22029824] Not found in the literature	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs.
DRAMP01438	GIFGKILGAGKKVLCGLSGLC	21	"Nigrocin-2JDa (Frogs, amphibians, animals)"	B3A0M6	Not found	Not found	Odorrana jingdongensis (Jingdong frog) (Rana jingdongensis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. Has hemolytic activity against rabbit erythrocytes. 
PTM: contains one disulfide bond 15-21. "	"[Ref.22917879]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=16 ?M), Staphylococcus aureus CIB 85462 (MIC=8 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25992 (MIC=16 ?M), Escherichia coli CIB 84492 (MIC=16 ?M);##Yeast: Candida albicans (MIC=63 ?M)."	[Ref:22917879] It has 80.3 ¡À 5.5% hemolytic activity at 128 ¦Ìg/ml against rabbit red blood cells	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22917879	J Proteomics. 2012 Oct 22;75(18):5807-5821.	"Liu J, Jiang J, Wu Z, Xie F."	"Antimicrobial peptides from the skin of the Asian frog, Odorrana jingdongensis: De novo sequencing and analysis of tandem mass spectrometry data."
DRAMP01439	GIFGKILGVGKKVLCGLSGMC	21	"Nigrocin-2JDb (Odorranain-H2; Frogs, amphibians, animals)"	B3A0M7	Not found	Not found	Odorrana jingdongensis (Jingdong frog) (Rana jingdongensis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. Has hemolytic activity against rabbit erythrocytes.
PTM: contains one disulfide bond 15-21. "	"[Ref.22917879]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=15 ?M), Staphylococcus aureus CIB 85462 (MIC=15 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25992 (MIC=8 ?M), Escherichia coli CIB 84492 (MIC=8 ?M);##Yeast: Candida albicans (MIC=31 ?M)."	[Ref:22917879] It has 88.4 ¡À 4.2% hemolytic activity at 128 ¦Ìg/ml against rabbit red blood cells	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Not found	22917879	J Proteomics. 2012 Oct 22;75(18):5807-5821.	"Liu J, Jiang J, Wu Z, Xie F."	"Antimicrobial peptides from the skin of the Asian frog, Odorrana jingdongensis: De novo sequencing and analysis of tandem mass spectrometry data."
DRAMP01447	GFSSIFRGVAKFASKGLGKDLAKLGVDLVACKISKQC	37	"Esculentin-2CHa (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Lithobates chiricahuensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: E. coli (MIC=5 ?M), K. pneumoniae (MIC=5 ?M), P. aeruginosa (MIC=5 ?M);##Gram-positive bacterium: S. aureus (MIC=5 ?M).##Yeast: C. albicans (MIC=10 ?M)."	[Ref.21262304] LC50=150 ?M against human erythrocytes	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	No cytotoxicity information found	Not found	21262304	Peptides. 2011 Apr;32(4):664-669.	"Conlon JM, Mechkarska M, Coquet L, Jouenne T, Leprince J, Vaudry H, Kolodziejek J, Nowotny N, King JD."	Characterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona.
DRAMP01452	RISFKKGKGSWIKNGLIKGIKGLGKEISLDVIRTGIDIAGCKIKGEC	47	"Esculentin-1LTa (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Hylarana latouchii (Broad-folded frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=0.6 ?M), Bacillus licheniformis X39 (MIC=10 ?M), Staphylococcus carnosus KHS (MIC=1.3 ?M), Rhodococcus rhodochrous X15 (MIC=0.3 ?M);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=5 ?M), Serratia rubidaea X01 (MIC=10 ?M), Psychrobacter faecalis X29 (MIC=0.6 ?M).##Yeast: Candida albicans ATCC2002 (MIC=80 ?M)."	[Ref.22426384] LD50>480 ¦ÌM against human erythrocytes	Cyclic	Free	Cyclization (Cys41 and Cys47)	Disulfide bond between Cys41 and Cys47.	L	No cytotoxicity information found	Not found	22426384	Biochimie. 2012 Jun;94(6):1317-1326.	"Wang H, Yu Z, Hu Y, Yu H, Ran R, Xia J, Wang D, Yang S, Yang X, Liu J."	"Molecular cloning and characterization of antimicrobial peptides from skin of the broad-folded frog, Hylarana latouchii."
DRAMP01456	GLFSILKGVGKIALKGLAKNMGKMGLDLVSCKISKEC	37	"Esculentin-2PLa (Frogs, amphibians, animals)"	"A7WNV5, D3UA57"	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana palustris (Pickerel frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against the Gram-negative bacterium E. coli, the Gram-positive bacterium: S. aureus and the yeast C. albicans.
Tissue specificity: Expressed by the skin glands.
PTM: Contains one disulfide bond 31-37."	Gram-negative bacterium: Escherichia coli (MIC=1 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=10 ?M).##Yeast: Candida albicans (MIC=49 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	No cytotoxicity information found	Not found	11087945	Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.	"Basir YJ, Knoop FC, Dulka J, Conlon JM."	"Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris."
DRAMP01479	GLFSKLNKKKIKSGLIKIIKTAGKEAGLEALRTGIDVIGCKIKGEC	46	"Esculentin-1CPa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Lithobates capito (North American New World frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Active against bacteria and fungi.	[Ref.19635516]Gram-negative bacterium: Escherichia coli (MIC=25 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=50 ?M);##Yeast: Candida albicans (MIC=25 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	No cytotoxicity information found	Not found	19635516	Peptides. 2009 Oct;30(10):1775-1781.	"Conlon JM, Meetani MA, Coquet L, Jouenne T, Leprince J, Vaudry H, Kolodziejek J, Nowotny N, King JD."	Antimicrobial peptides from the skin secretions of the New World frogs Lithobates capito and Lithobates warszewitschii (Ranidae).
DRAMP01480	GFFSLIKGVAKIATKGLAKNLGKMGLDLVGCKISKEC	37	"Esculentin-2CPa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Lithobates capito (North American New World frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Active against bacteria and fungi.	[Ref.19635516]Gram-negative bacterium: Escherichia coli (MIC=25 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=50 ?M);##Yeast: Candida albicans (MIC=25 ?M)	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	No cytotoxicity information found	Not found	19635516	Peptides. 2009 Oct;30(10):1775-1781.	"Conlon JM, Meetani MA, Coquet L, Jouenne T, Leprince J, Vaudry H, Kolodziejek J, Nowotny N, King JD."	Antimicrobial peptides from the skin secretions of the New World frogs Lithobates capito and Lithobates warszewitschii (Ranidae).
DRAMP01483	RIFSKIGGKAIKNLILKGIKNIGKEVGMDVIRTGIDVAGCKIKGEC	46	"Esculentin-1ISb (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana ishikawae (Japanese Endangered frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity.	"Gram-negative bacterium: Escherichia coli (MC=3.1 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.1 ?M), Staphylococcus aureus (MRSA) (MIC=12.5 ?M), Bacillus subtilis (MIC=12.5 ?M).##Yeast: Candida albicans (MIC=50 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	No cytotoxicity information found	Not found	21193000	Peptides. 2011 Apr;32(4):670-676. 	"Iwakoshi-Ukena E, Ukena K, Okimoto A, Soga M, Okada G, Sano N, Fujii T, Sugawara Y, Sumida M."	Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae.
DRAMP01484	GIFSLIKGAAKLITKTVAKEAGKTGLELMACKVTNQC	37	"Esculentin-2ISa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana ishikawae (Japanese Endangered frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity.	"Gram-negative bacterium: Escherichia coli (MC=12.5 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.1 ?M), Staphylococcus aureus (MRSA) (MIC=25 ?M), Bacillus subtilis (MIC=6.3 ?M).##Yeast: Candida albicans (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	No cytotoxicity information found	Not found	21193000	Peptides. 2011 Apr;32(4):670-676. 	"Iwakoshi-Ukena E, Ukena K, Okimoto A, Soga M, Okada G, Sano N, Fujii T, Sugawara Y, Sumida M."	Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae.
DRAMP01486	GLFSKFAGKGIKNLIFKGVKHIGKEVGMDVIRTGIDVAGCKIKGEC	46	"Esculentin-1GRa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana grahami (Odorrana andersonii)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Shows antibacterial activity, also activity against fungus C. albicans."	Gram-negative bacterium: Escherichia coli (MIC=6 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=12.5 ?M).##Yeast: Candida albicans (MIC>50 ?M).	[Ref.16621155] LC50=210 ¦ÌM against human erythrocytes. 	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	No cytotoxicity information found	Not found	16621155	Peptides 2006; 27: 2111-2117.	"Conlon JM, Al-Ghaferi N, Abraham B, Jiansheng H, Cosette P, Leprince J, Jouenne T, Vaudry H."	"Antimicrobial peptides from diverse families isolated from the skin of the Asia frog, Rana Grahami."
DRAMP01493	GLFSKFVGKGIKNFLIKGVKHIGKEVGMDVIRVGIDVAGCKIKGVC	46	"Esculentin-1-OA1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-positive bacteria: Bacillus pyocyaneus CMCCB 10104 (MIC=1.2 ?g/mL), Staphylococcus aureus ATCC 25923 (MIC=1.2 ?g/mL).##Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=1.2 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=2.4 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01494	GLFSKFSGKGIKNFLIKGVKHIGKEVGMDVIRTGIDVAGCKIKGEC	46	"Esculentin-1-OA2 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=2.5 ?g/mL);##Gram-positive bacteria: Bacillus pyocyaneus CMCCB 10104 (MIC=2.5 ?g/mL), Staphylococcus aureus ATCC 25923 (MIC=1.3 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=1.3 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01495	GLFSKFAGKGIKDLIFKGVKHIGKEVGMDVIRVGIDVAGCKIKGVC	46	"Esculentin-1-OA3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=5.4 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=5.4 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=2.7 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=2.7 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01496	GLFTKFAGKGIKDLIFKGVKHIGKEVGMDVIRVGIDVAGCKIKGVC	46	"Esculentin-1-OA4 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=5.6 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2.8 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=2.8 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=5.6 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01497	GLFSKFAGKGIKNFLIKGVKHIGKEVGMDVIRVGIDVAGCKIKGVC	46	"Esculentin-1-OA5 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=3.4 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=1.7 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=3.4 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=1.7 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01499	GIFSKISGKAIKNLFIKGAKNVGKEVGMDVVRTGIDVVGCKIKGEC	46	"Esculentin-1-OR1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=8.8 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=4.4 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=17.6 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=8.8 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01501	GIFSKISGKAIKNLFIKGAKNVGKRVGMDVVRTGMDVVGCKIKGEC	46	"Esculentin-1-OR3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=5.5 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=11 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=11 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=11 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01502	GIFSKISGKAIKNLFIKGAENVGKHVGIDVVRTGIDVVGCKIKGEC	46	"Esculentin-1-OR4 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=8.6 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=8.6 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=8.6 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=8.6 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01503	GIFSKISGKAIKNLFIKGAKNVGKEVGIDVVRTGMDVVGCKIKGEC	46	"Esculentin-1-OR5 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=4.1 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=4.1 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=8.2 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=2.1 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01504	GIFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC	37	"Esculentin-2-OA1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=8.5 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=4.3 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=4.3 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=8.5 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01505	GLFTLIKGAAKLIGKTTAKEAGKTGKLEMACKITNQC	37	"Esculentin-2-OA2 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=10.8 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=21.6 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=21.6 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01507	GVFTLIKGATQLIGKTLGKELGKTGLELMACKITNQC	37	"Esculentin-2-OR1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=10.8 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=21.6 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=21.6 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=10.8 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01508	GVFTLIKGATQLIGKTLGKEVGKTGLELMACKITKQC	37	"Esculentin-2-OR2 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=8.1 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=4.1 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=16.2 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=8.1 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01509	GVFTLLKGATQLIGKTLGKELGKTGLELMACKITNQC	37	"Esculentin-2-OR3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=7.9 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=7.9 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=7.9 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=15.8 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01510	GVFTLIKGATQLIGKTLGKELGKTGLELMACKITEQC	37	"Esculentin-2-OR4 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=3.6 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=3.6 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=3.6 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=3.6 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01511	GVFTLIKGATQLIGKTLGKELGKTGLEIMACKITKQC	37	"Esculentin-2-OR5 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=15.8 ?g/mL);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=15.8 ?g/mL), Bacillus pyocyaneus CMCCB 10104 (MIC=15.8 ?g/mL).##Yeast: Candida albicans ATCC 2002 (MIC=7.9 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	[Ref.22029824]No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01513	GIFSKLGRKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC	46	"Esculentin-1 (Frogs, amphibians, animals)"	P32414	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana esculenta (Edible frog) (Pelophylax esculentus)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans.  Has hemolytic activity.	"Gram-negative bacteria: Escherichia coli D21 (MIC=0.2 ?M), Pseudomonas aeruginosaATCC15692 (MIC=0.7 ?M);##Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=0.1 ?M), Staphylococcus aureus Cowan1 (MIC=0.4 ?M).##Fungi: Candida albicans (MIC=0.5 ?M), Saccharomyces cerevisiae (MIC=0.9 ?M)."	[Ref. 8163497] LC>100¦ÌM	Cyclic	Free	Cyclization (Cys40 and Cys46)	Disulfide bond between Cys40 and Cys46.	L	[Ref.8508915]No cytotoxicity information found	Not found	8508915	FEBS Lett. 1993 Jun 14;324(2):159-161.	"Simmaco M, Mignogna G, Barra D, Bossa F."	Novel antimicrobial peptides from skin secretion of the European frog Rana esculenta.
DRAMP01524	SIRDKIKTIAIDLAKSAGTGVLKTLICKLDKSC	33	"Rugosin-RN1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana nigrovittata	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has weak hemolytic activity gainst rabbit red cells.	"[Ref.19778602]Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=4.69 ?g/ml), Bacillus subtilis (MIC=9.38 ?g/ml);##Gram-negative bacterium: Escherichia coli ML-35P (MIC=25.00 ?g/ml);##Yeast: Candida albicans ATCC2002 (MIC=5.63 ?g/ml)"	[Ref:19778602]Show weak hemolytic activity against rabbit red cells	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bridge between Cys27 and Cys33.	L	[Ref.19778602]No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71.	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP01525	SIRDKIKTIAIDLAKSAGMGILKTLICKLDKSC	33	"Rugosin-RN3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana nigrovittata	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=16.51 ?g/ml), Bacillus subtilis (MIC=18.75 ?g/ml);##Gram-negative bacterium: Escherichia coli ML-35P (MIC=25.00 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=15.00 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bridge between Cys27 and Cys33.	L	[Ref.19778602]No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71.	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP01526	SIRDKIKTIAIDLAKSAGTGVLKTLICKLNKSC	33	"Rugosin-RN5 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana nigrovittata	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=15.00 ?g/ml), Staphylococcus aureus ATCC43300 (MRSA) (MIC=12.50 ?g/ml), Bacillus subtilis (MIC=18.75 ?g/ml);##Gram-negative bacterium: Escherichia coli ML-35P (MIC=25.00 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=18.75 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bridge between Cys27 and Cys33.	L	[Ref.19778602]No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71.	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP01539	FKTWKRPPFQTSCWGIIKE	19	"Nigroain-C2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana nigrovittata (Black-striped frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=27.50 ?g/ml), S. aureus ATCC43300 (MIC=55.00 ?g/ml), Bacillus subtilis (MIC=110.00 ?g/ml);##Gram-negative bacteria: Escherichia coli ML-35P (MIC=110.00 ?g/ml), Pseudomonas aeruginosa PA01 (MIC=55.00 ?g/ml), Pseudomonas aeruginosa ATCC27853 (MIC=55.00 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=13.75 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	Free	L	[Ref.19778602]No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71. 	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP01543	DCTRWIIGINGRICRD	16	"Nigroain-E1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana nigrovittata (Black-striped frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Function: Has hemolytic activity against rabbit red cells.	[Ref.19778602]Gram-positive bacterium: Staphylococcus aureus ATCC25923 (MIC=18.75 ?g/ml);##Yeast: Candida albicans ATCC2002 (MIC=75 ?g/ml).	[Ref:19778602]7.62¡À1.6% hemolytic activity at 100 ?g/ml against rabbit red cells	Cyclic	Free	Free	Disulfide bridge between Cys2 and Cys14.	L	[Ref.19778602]No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71. 	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP01546	SLWETIKNAGKGFIQNLDKIR	21	"Nigroain-K1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana nigrovittata (Black-striped frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. Also has hemolytic activity against rabbit red cells.	"[Ref.19778602]Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=9.38 ?g/ml), Bacillus subtilis (MIC=21.88 ?g/ml);##Gram-negative bacterium: Escherichia coli ML-35P (MIC=37.50 ?g/ml);##Yeast: Candida albicans ATCC2002 (MIC=32.74 ?g/ml)."	[Ref:19778602]22.49 ¡À 4.8% hemolytic activity at 100 ?g/ml against rabbit red cells	Linear	Free	Free	Free	L	[Ref.19778602]No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71. 	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP01547	SLWETIKNAGKGFILNILDKIRCKVAGGCKT	31	"Nigroain-K2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana nigrovittata (Black-striped frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. Also has hemolytic activity against rabbit red cells.	"[Ref.19778602]Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=11.25 ?g/ml), Staphylococcus aureus ATCC43300 (MIC=9.38 ?g/ml), Bacillus subtilis (MIC=9.38 ?g/ml);##Gram-positive bacteria: Escherichia coli ML-35P (MIC=25.00 ?g/ml), Pseudomonas aeruginosa PA01 (MIC=25.00 ?g/ml), Pseudomonas aeruginosa ATCC27853 (MIC=25.00 ?g/ml);##Yeast: Candida albicans ATCC2002 (MIC=15.00 ?g/ml)"	[Ref:19778602]85.52 ¡À 3.26% hemolytic activity at 50 ?g/ml against rabbit red cells	Cyclic	Free	Free	Disulfide bridge between Cys23 and Cys29.	L	[Ref.19778602]No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71. 	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP01560	GLFGVLGSIAKHVLPHVVPVIAEKL	25	"Caerin-1.9 (Frogs, amphibians, animals)"	P81252	Belongs to the frog skin active peptide family (Caerin subfamily)	Not found	Litoria chloris (Blue-thighed frog) (frog skin active peptide family)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral"	Protein level	Not found	Not found	None	"Function: Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes. Each caerin displays a different antimicrobial specificity.
Tissue specificity: Expressed by the skin dorsal glands.
Domain: Contains two amphipathic alpha helix regions separated by a region of less-defined helicity and greater flexibility (By similarity).
PTM: C-terminal amidation.
Miscellaneous: Caerin 1.9 completely inhibited HIV infection of T cells within minutes of exposure to virus at concentrations that were not toxic to target cells (J Virol. 2005 Sep;79(18):11598-606)."	"[Ref.15203252]Gram-positive bacteria: Bacillus cereus (MIC=100 ?g/ml), Leuconostoc lactis (MIC=12 ?g/ml), Listeria innocua (MIC=50 ?g/ml), Micrococcus luteus (MIC=50 ?g/ml), Staphylococcus aureus (MIC=100 ?g/ml), Staphylococcus epidermis (MIC=25 ?g/ml), Streptococcus uberis (MIC=50 ?g/ml);##Gram-negative bacterium: Pasteurella multocida (MIC=50 ?g/ml). ##[Ref.16140737]Virus:HIV:inhibit 50% of PBS-treated HIV infection of T cells(IC50=1.2 ¦ÌM);inhibition of HIV transfer by dendritic cells to T cells(IC50=1.6 ¦ÌM).##[Ref.26026377]Virus:HIV: inhibition of HIV Pseudovirus (PsV) infection in CD4+ T cells(IC50=4 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	"[Ref.26026377]CD4+ T Lymphocytes:50% cell death at 20	?M."	Not found	26026377##16140737##15203252##9516047	Peptides. 2015 Sep;71:296-303. ##J Virol. 2005 Sep;79(18):11598-606. ##Peptides. 2004 Jun;25(6):1035-1054.##J Pept Res. 1998 Feb;51(2):121-126.	"VanCompernolle S, Smith PB, Bowie JH, Tyler MJ, Unutmaz D, Rollins-Smith LA.##VanCompernolle SE, Taylor RJ, Oswald-Richter K, Jiang J, Youree BE, Bowie JH, Tyler MJ, Conlon JM, Wade D, Aiken C, Dermody TS, KewalRamani VN, Rollins-Smith LA, Unutmaz D.##Apponyi MA, Pukala TL, Brinkworth CS, Maselli VM, Bowie JH, Tyler MJ, Booker GW, Wallace JC, Carver JA, Separovic F, Doyle J, Llewellyn LE.##Steinborner ST, Currie GJ, Bowie JH, Wallace JC, Tyler MJ."	"Inhibition of HIV infection by caerin 1 antimicrobial peptides.##Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells.##Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance.##New antibiotic caerin 1 peptides from the skin secretion of the Australian tree frog Litoria chloris. Comparison of the activities of the caerin 1 peptides from the genus Litoria."
DRAMP01627	YPPKPESPGEDASPEEMNKYLTALRHYINLVTRQRY	36	"Skin peptide tyrosine-tyrosine (Skin-PYY; SPYY; Frogs, amphibians, animals)"	P80952	Belongs to the NPY family	Not found	Phyllomedusa bicolor (Two-colored leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Shows a broad spectrum of antibacterial activity against Gram-positive and Gram-negative bacteria, yeast and fungi.
Tissue specificity: Skin.
PTM: C-terminal amidation (By similarity)."	"Gram-negative bacteria: Aeromonas caviae (MIC=40 ?g/ml), Escherichia coli (MIC=10 ?g/ml);##Gram-positive bacteria: Enterococcus faecalis (MIC=10 ?g/ml), Nocardia brasiliensis (MIC=20 ?g/ml).##Fungi: Cryptococcus neoformans (MIC=20 ?g/ml), Candida albicans (MIC=15 ?g/ml), Microsporum canis (MIC=10 ?g/ml), Tricophyton rubrum (MIC=15 ?g/ml), Arthroderma simii (MIC=10 ?g/ml), Aspergillus fumigatus (MIC=80 ?g/ml), Aspergillus niger (MIC>100 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.8601432]<20% cytotoxic against murine macrophages at the concentration up to 100¦Ìg/ml##[Ref.7937944]No cytotoxicity information found	Cell membrane	7937944##8601432	Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10295-10299.##FEBS Lett. 1996 Feb 19;380(3):237-240.	"Mor A, Chartrel N, Vaudry H, Nicolas P.##Vouldoukis I, Shai Y, Nicolas P, Mor A."	"Skin peptide tyrosine-tyrosine, a member of the pancreatic polypeptide family: isolation, structure, synthesis, and endocrine activity.##Broad spectrum antibiotic activity of the skin-PYY."
DRAMP01638	GLWSKIKEAAKAAGKAALNAVTGLVNQGDQPS	32	"Dermaseptin-L1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Hylomantis lemur (Lemur leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: Escherichia coli (MIC=8 ?M).##Fungi: Batrachochytrium dendrobatidis (MIC>100 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Free	Free	L	[Ref.17561225]Displayed cytotoxic against HepG2 cells(LC50=45¦ÌM)	Not found	17561225	Toxicon. 2007 Sep 15;50(4):498-506.	"Conlon JM, Woodhams DC, Raza H, Coquet L, Leprince J, Jouenne T, Vaudry H, Rollins-Smith LA."	Peptides with differential cytolytic activity from skin secretions of the lemur leaf frog Hylomantis lemur (Hylidae: Phyllomedusinae).
DRAMP01646	GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV	33	"Adenoregulin (Dermaseptin BII; Dermaseptin B2; Frogs, amphibians, animals)"	"P31107, P80283"	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	ADR	Phyllomedusa bicolor (Two-colored leaf frog) (Rana bicolor)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Fountion: Enhances binding of agonists to adenosine A1 receptors, adenosine A2a receptors, alpha-2 adrenergic receptors and 5-hydroxytryptamine 1A receptors. Enhances guanyl nucleotide exchange which may result in the conversion of receptors to a high affinity state complexed with guanyl nucleotide free G-protein. Affects human behavior eliciting profound malaise, followed by listlessness and then euphoria. Possesses a potent antimicrobial activity against bacteria, fungi and protozoa. Lack hemolytic activity. Probably acts by disturbing membrane functions with its amphipathic structure.
Tissue specificity: Expressed by the skin glands.
PTM: C-terminal amidation at V33 (Amidation in vitro increases antimicrobial activity against some microorganisms such as T. album and S. cerevisia)."	"[Ref.8306981]Fungi: Microsporum canis (IP 1194) (MIC=10 ?g/ml), Tricophyton rubrum (IP 1400-82) (MIC=15 ?g/ml), Arthroderma simii (IP 1063-74) (MIC=30 ?g/ml), Aspergillus fumigatus IP (1025-70) (MIC=125 ?g/ml), Aerornonas caviae (IP 67-16 T) (MIC=60 ?g/ml), Cryptococcus neoformans (IP 960-67) (MIC=15 ?g/ml), Cryptococcus neoformans (IP 962-67) (MIC=15 ?g/ml), Candida albicans (IP 884-65) (MIC=15 ?g/ml);##Gram-negative bacterium: Escherichia coli (IP 76-24) (MIC=15 ?g/ml);##Gram-positive bacterium: Nocardia brasiliensis (IP 16-80) (MIC=30 ?g/ml)."	[Ref:8306981]Lack hemolytic activity against rabbit red blood cells	Linear	Free	Free	Free	L	[Ref.8306981]No cytotoxicity information found##[Ref.1438301]No cytotoxicity information found##[Ref.7842473]No cytotoxicity information found##[Ref.8565049]No cytotoxicity information found	Not found	8306981##1438301##7842473##8565049	"Eur J Biochem 1994, 219 (1-2):145-154.##Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10960-10963.##Cell Mol Neurobiol. 1994 Apr;14(2):133-157.##Cell Mol Neurobiol. 1995 Aug;15(4):465-493."	"Mor, A, Nicolas, P.##Daly JW, Caceres J, Moni RW, Gusovsky F, Moos M Jr, Seamon KB, Milton K, Myers CW.##Shin Y, Moni RW, Lueders JE, Daly JW.##Moni RW, Romero FS, Daly JW."	"Isolation and structure of novel defensive peptides from frog skin.##Frog secretions and hunting magic in the upper Amazon: identification of a peptide that interacts with an adenosine receptor.##Effects of the amphiphilic peptides mastoparan and adenoregulin on receptor binding, G proteins, phosphoinositide breakdown, cyclic AMP generation, and calcium influx.##The amphiphilic peptide adenoregulin enhances agonist binding to A1-adenosine receptors and [35S]GTP gamma S to brain membranes."
DRAMP01648	GLVTSLIKGAGKLLGGLFGSVTGGQS	26	"Dermaseptin-like PBN2 (DRP-PBN2; Plasticin-B1a; Frogs, amphibians, animals)"	Q800R4	Not found	Not found	Phyllomedusa bicolor (Two-colored leaf frog) (Rana bicolor)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	"Function: Possesses a potent antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and fungi. Probably acts by disturbing membrane functions with its amphipathic structure."	"Gram-negative bacteria: Escherichia coli B (MIC=1.5 ?M), Salmonella typhimurium (MIC=3.1 ?M), Salmonella enteritidis (MIC=1.5 ?M), Enterobacter cloacae (MIC=12.5 ?M), Klebsiella pneumoniae (MIC=0.8 ?M);##Gram-positive bacteria: Aerococcus viridans (MIC=3.1 ?M), Bacillus megaterium (MIC=0.8 ?M), Staphylococcus aureus (MIC=3.1 ?M), Staphylococcus haemolyticus (MIC=0.8 ?M).##Fungi: Saccaromyces cerevisiae (MIC=3.1 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	Free	L	[Ref.12709067]No cytotoxicity information found##[Ref.15222751]No cytotoxicity information found	Not found	12709067##15222751	Eur J Biochem. 2003 May;270(9):2068-2081.##Biochemistry. 2004 Jul 6;43(26):8391-8409.	"Vanhoye D, Bruston F, Nicolas P, Amiche M.##Vanhoye D, Bruston F, El Amri S, Ladram A, Amiche M, Nicolas P."	"Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain.##Membrane association, electrostatic sequestration, and cytotoxicity of Gly-Leu-rich peptide orthologs with differing functions."
DRAMP01649	AMWKDVLKKIGTVALHAGKAALGAVADTISQ	31	"Dermaseptin-BI (Dermaseptin B1; Frogs, amphibians, animals)"	P80282	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa bicolor (Two-colored leaf frog) (Rana bicolor)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses a potent antimicrobial activity against bacteria, fungi and protozoa. Probably acts by disturbing membrane functions with its amphipathic structure.
Tissue specificity: Expressed by the skin glands.
PTM: C-terminal amidation (Potential)."	"Gram-negative bacterium: Escherichia coli (IP 76-24) (MIC=15 ?g/ml);##Gram-positive bacterium: Nocardia brasiliensis (IP 16-80) (MIC=30 ?g/ml).##Fungi: Tricophyton rubrum (IP 1400-82) (MIC=15 ?g/ml), Microsporum canis (IP 1194) (MIC=10?g/ml), Arthroderma simii (IP 1063-74) (MIC=30 ?g/ml), Cryptococcus neoformans (IP 960-67) (MIC=15 ?g/ml), Cryptococcus neofonnans (IP 962-67) (MIC=15 ?g/ml), Aspergillus fumigatus (IP 1025-70)(MIC=125 ?g/ml), Aerornonas caviae (IP 67-16 T) (MIC=60 ?g/ml), Candida albicans (IP 884-65) (MIC=15 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.8306981]No cytotoxicity information found##[Ref.8074751]No cytotoxicity information found	Not found	8306981##8074751	Eur J Biochem. 1994 Jan 15;219(1-2):145-154.##J Biol Chem. 1994 Jul 8;269(27):17847-17852.	"Mor A, Nicolas P.##Amiche M, Ducancel F, Mor A, Boulain JC, Menez A, Nicolas P."	"Isolation and structure of novel defensive peptides from frog skin.##Precursors of vertebrate peptide antibiotics dermaseptin b and adenoregulin have extensive sequence identities with precursors of opioid peptides dermorphin, dermenkephalin, and deltorphins."
DRAMP01668	ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ	34	"Dermaseptin-1 (DS I; Dermaseptin-S1, DS1; Frogs, amphibians, animals)"	"P24302, P80277"	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa sauvagei (Sauvage's leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal"	Protein level	Alpha helix (CD)	Not found	None	"Function: Possesses a potent antimicrobial activity against bacteria, fungi and protozoa. Probably acts by disturbing membrane functions with its amphipathic structure. This peptide could also inhibit HIV infection at a concentration that is also toxic to T cells (J Virol 2005; 79:11598-11606).
Tissue specificity: Expressed by the skin glands."	"Fungi: Microsporum canis (IP 1194) (MIC=50 ?g/ml), Tricophyton rubrum (IP 1400-82) (MIC=100 ?g/ml), Arthroderma simii (IP 1063-74) (MIC=100 ?g/ml), Aspergillus fumigatus (IP 1025-70) (MIC=100 ?g/ml), Aerornonas caviae IP (67-16) T (MIC=50 ?g/ml), Cryptococcus neoformans (IP 960-67) (MIC=15 ?g/ml), Cryptococcus neoformans (IP 962-67) (MIC=15 ?g/ml), Candida albicans (IP 884-65) (MIC=60 ?g/ml); ##Gram-negative bacterium: Escherichia coli (IP 76-24) (MIC=5 ?g/ml);##Gram-positive bacterium: Nocardia brasiliensis (IP 16-80) (MIC=200 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Free	Free	L	[Ref.1909573]No cytotoxicity information found##[Ref.8306981]No cytotoxicity information found	Cell membrane	1909573##8306981	Biochemistry. 1991 Sep 10;30(36):8824-8830.##Eur J Biochem. 1994 Jan 15;219(1-2):145-154. 	"Mor A, Nguyen VH, Delfour A, Migliore-Samour D, Nicolas P.##Mor A, Nicolas P."	"Isolation, amino acid sequence, and synthesis of dermaseptin, a novel antimicrobial peptide of amphibian skin.##Isolation and structure of novel defensive peptides from frog skin."
DRAMP01764	FLPILGKLLSGIL	13	"Temporin-1TGa (Frogs, amphibians, animals)"	Q2PGA8	Belongs to the frog skin active peptide family (Brevinin subfamily)	tmpTGa	Rana tagoi (Tago frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus (MIC=15 ?M);##Gram-negative bacterium: Escherichia coli (MIC>100 ?M).##Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.12804591]No cytotoxicity information found##[Ref.16675060]No cytotoxicity information found	Not found	12804591##16675060	Biochem Biophys Res Commun. 2003 Jun 27;306(2):496-500.##Peptides. 2006 Sep;27(9):2124-2128.	"Conlon JM, Sonnevend A, Patel M, Camasamudram V, Nowotny N, Zilahi E, Iwamuro S, Nielsen PF, P??l T.##Iwamuro S, Nakamura M, Ohnuma A, Conlon JM."	"A melittin-related peptide from the skin of the Japanese frog, Rana tagoi, with antimicrobial and cytolytic properties.##Molecular cloning and sequence analyses of preprotemporin mRNAs containing premature stop codons from extradermal tissues of Rana tagoi."
DRAMP01776	FLPIVTNLLSGLLGK	15	"Temporin-1Sb (Temporin-SHb; Frogs, amphibians, animals)"	B3KYH5	Belongs to the frog skin active peptide family (Brevinin subfamily)	preproTemp-1Sb	Pelophylax saharicus (Sahara frog) (Rana saharica)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: Activity against Gram-positive and Gram-negative bacteria, and has strong hemolytic activity against human erythrocytes."	"[Ref.18584916]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=58 ?M), Enterococcus faecalis ATCC 29212 (MIC>116 ?M), Bacillus megaterium (MIC=46 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=231 ?M), Escherichia coli ATCC 35218 (MIC>116 ?M);##Fungi: Aspergillus flavus (MIC=58 ?M)."	[Ref:18584916]LC50>116 ¦ÌM against human erythrocytes	Linear	Free	Amidation	Free	L	[Ref.18584916]No cytotoxicity information found	Not found	18584916	Peptides. 2008 Sep;29(9):1526-1523.	"Abbassi F, Oury B, Blasco T, Sereno D, Bolbach G, Nicolas P, Hani K, Amiche M, Ladram A"	"Isolation, characterization and molecular cloning of new temporins from the skin of the North African ranid Pelophylax saharica."
DRAMP01777	FLSHIAGFLSNLFGK	15	"Temporin-1Sc (Temporin-SHc; Frogs, amphibians, animals)"	B3KYH6	Belongs to the frog skin active peptide family (Brevinin subfamily)	preproTemp-1Sc	Pelophylax saharicus (Sahara frog) (Rana saharica)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Alpha helix	Not found	None	"Function: Activity against a range of Gram-positive and Gram-negative bacteria, and has hemolytic activity against human erythrocytes."	"[Ref.18584916]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=10 ?g/ml), Enterococcus faecalis ATCC 29212 (MIC>80 ?g/ml), Bacillus megaterium (MIC=4 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=161 ?g/ml), Escherichia coli ATCC 35218 (MIC>80 ?g/ml), Pseudomonas aeruginosa ATCC 27853 (MIC>161 ?g/ml);##Fungi: Aspergillus flavus (MIC=10 ?g/ml), Candida albicans ATCC 90028 (MIC=20 ?g/ml), Candida parapsilosis ATCC 22019 (MIC=20 ?g/ml), Saccharomyces cerevisiae (MIC=10 ?g/ml)."	[Ref:18584916]LC50>80 ¦ÌM against human erythrocytes	Linear	Free	Amidation	Free	L	[Ref.18584916]No cytotoxicity information found	Not found	18584916	Peptides. 2008 Sep;29(9):1526-1523.	"Abbassi F, Oury B, Blasco T, Sereno D, Bolbach G, Nicolas P, Hani K, Amiche M, Ladram A"	"Isolation, characterization and molecular cloning of new temporins from the skin of the North African ranid Pelophylax saharica."
DRAMP01780	FLSGIVGMLGKLF	13	"Temporin-SHa (Temporin-1Sa; Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Pelophylax saharica (North Africa)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus (MIC=3 ?M), Bacillus megaterium (MIC=2 ?M);##Gram-negative bacterium: Escherichia coli (MIC=10 ?M).##Yeast: Candida albicans (MIC=16 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.31614561]Display cytotoxic against human gastric cells(N87 cell:IC50=1558 ¡À 324¦ÌM)	Not found	31614561	Biomolecules. 2019 Oct 11;9(10):598.	"Olleik H, Baydoun E, Perrier J, Hijazi A, Raymond J, Manzoni M, Dupuis L, Pauleau G, Goudard Y, Vill¨¦on B, Goin G, Sockeel P, Choudhary MI, Pasquale ED, Nadeem-Ul-Haque M, Ali H, Khan AI, Shaheen F, Maresca M. "	Temporin-SHa and Its Analogs as Potential Candidates for the Treatment of Helicobacter pylori. 
DRAMP01787	AILTTLANWARKFL	14	"Temporin-HN1 (Frogs, amphibians, animals)"	E7EKD0	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana hainanensis (Hainan odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has hemolytic activity against washed human erythrocytes (IC50=75 ?M).	"[Ref.22450466]Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=37.5 ?M), Staphylococcus carnosus KHS (MIC=37.5 ?M), Bacillus licheniformis X39 (MIC=19 ?M), Rhodococcus rhodochrous X15 (MIC=4.8 ?M);##Gram-negative bacteria: Psychrobacter faecalis X29 (MIC=75 ?M);##Fungi: Slime mould 090223 (MIC=19 ?M), Candida albicans ATCC2002 (MIC=75 ?M)."	[Ref:22450466]IC50=75 ?M against washed human erythrocytes	Linear	Free	Amidation	Free	L	[Ref.22450466]No cytotoxicity information found	Not found	22450466	Peptides. 2012 Jun;35(2):285-290. 	"Wang H, Yu Z, Hu Y, Li F, Liu L, Zheng H, Meng H, Yang S, Yang X, Liu J."	"Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis."
DRAMP01788	NILNTIINLAKKIL	14	"Temporin-HN2 (Frogs, amphibians, animals)"	E7EKD4	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana hainanensis (Hainan odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=4.8 ?M), Staphylococcus carnosus KHS (MIC=19 ?M), Bacillus licheniformis X39 (MIC=19 ?M),Rhodococcus rhodochrous X15 (MIC=2.4 ?M);##Gram-negative bacterium: Psychrobacter faecalis X29 (MIC=37.5 ?M).##Fungi: Slime mould 090223 (MIC=9.5 ?M) and Candida albicans ATCC2002 (MIC=9.5 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.22450466]No cytotoxicity information found	Not found	22450466	Peptides. 2012 Jun;35(2):285-290. 	"Wang H, Yu Z, Hu Y, Li F, Liu L, Zheng H, Meng H, Yang S, Yang X, Liu J."	"Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis."
DRAMP01789	FLSSIGKILGNLL	13	"Temporin-1Va (Temporin 1Va; Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana virgatipes (Ranidae) (Aquarana)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: It also has weak hemolytic activty.	"[Ref.15996769]Gram-positive bacteria: Staphylococcus aureus NCTC8325 (MIC=10 ?M), S. aureus (MRSA) T7/20 (MIC=20 ?M), S. epidermidis RP62A (MIC=20 ?M), Enterococcus faecalis ATCC 29212 (MIC=40 ?M), Streptococcus group B HNTCC 80130 (MIC=20 ?M);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=40 ?M), Klebsiella pneumoniae KK3 9904 (MIC=80 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=160 ?M), Enterobacter cloacae HNTCC 53001 (MIC=40 ?M);##Yeast: Candida albicans ATCC 90028 (MIC=160 ?M)."	[Ref:15996769]LD50=120 ¦ÌM against washed human erythrocytes	Linear	Free	Amidation	Free	L	[Ref.15996769]No cytotoxicity information found	Not found	15996769	Regul Pept. 2005 Nov;131(1-3):38-45.	"Conlon JM, Abraham B, Sonnevend A, Jouenne T, Cosette P, Leprince J, Vaudry H, Bevier CR."	"Purification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana). "
DRAMP01807	FLPLVLGALSGILPKIL	17	"Temporin-RN1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana nigrovittata	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus (MIC=4.69 ?g/ml);##Gram-negative bacterium: Pseudomonas aeruginosa PAO1 (MIC=4.7 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.19778602]No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71. 	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP01808	FFPLLFGALSSHLPKLF	17	"Temporin-RN3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana nigrovittata	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus (MIC=3.75 ?g/ml);##Gram-negative bacterium: Pseudomonas aeruginosa PAO1 (MIC=3.75 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.19778602]No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71. 	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP01818	NFLGTLVNLAKKIL	14	"Temporin-1CSd (Temporin-1DRb; Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana cascadae (Cascades frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: Escherichia coli (MIC=64 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=16 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Linear	Free	Amidation	Free	L	[Ref.17451843]No cytotoxicity information found	Not found	17451843	Peptides 2007; 28: 1268-1274.	"Conlon JM, Al-Dhaheri A, Al-Mutawa E, Al-Kharrge R, Ahmed E, Kolodziejek J, Nowotny N, Nielsen PF, Davidson C."	Peptide defenses of the Cascades frog Rana cascadae: implications for the evolutionary history of frogs of the Amerana species group.
DRAMP01391	GCSRWIIGIHGQICRD	16	"Odorranain-U1 (OdU1; Frogs, amphibians, animals)"	A6MBS4	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Odorranain-U1 adopts 60.2% 	None	Function: Odorranain-U1 exhibites moderate antimicrobial activities against all of the tested microbes.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC>100 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=75.00 ¦Ìg/ml), Bacillus subtilis (MIC=9.37 ¦Ìg/ml).##Yeast: Candida albicans (MIC=9.37 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01844	GIKDWIKGAAKKLIKTVASNIANQ	24	"Ascaphin-5 (Frogs, amphibians, animals)"	P0CJ29	Belongs to the ascaphin family	Not found	Ascaphus truei (Coastal tailed frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Antimicrobial peptide that shows higher potency against Gram-negative bacteria than against Gram-positive bacteria. Tissue specificity: Expressed by the skin glands.	"[Ref.15207717]Gram-negative bacteria: Escherichia coli (MIC=6 ?M), Pseudomonas aeruginosa (MIC=13 ?M), Enterobacter cloacae (MIC=6 ?M), Klebsiella pneumoniae (MIC=13 ?M), Proteus mirabilis (MIC>100 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=50 ?M), Staphylococcus epidermidis (MIC=13 ?M), Enterococcus faecalis (MIC>100 ?M), Streptococcus Group B (MIC=6 ?M);##Yeast: Candida albicans (MIC=100 ?M)."	[Ref.15207717]Not found	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15207717	Biochem Biophys Res Commun. 2004 Jul 16;320(1):170-175.	"Conlon JM, Sonnevend A, Davidson C, Smith DD, Nielsen PF."	"The ascaphins: a family of antimicrobial peptides from the skin secretions of the most primitive extant frog, Ascaphus truei."
DRAMP01849	DSMGAVKLAKLLIDKMKCEVTKAC	24	"Jindongenin-1a (JD1a; Frogs, amphibians, animals)"	G3ETQ2	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Amolops jingdongensis (Chinese torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Displays broad-spectrum antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Also displays antifungal activity against C. albicans ATCC 2002. Has hemolytic activity, low cytotoxicity and low antioxidant activity."	"[Ref.21816202]Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=17 ?M), Enterococcus faecalis ATCC29212 (MIC=60 ?M), Staphylococcus aureus (IS 10#)(MIC=40 ?M);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=10 ?M), Enterobacter cloacae ATCC13047 (MIC=40 ?M), Klebsiella pneumoniae ATCC700603 (MIC=15 ?M), Bacillus pyocyaneus CMCCB1010 (MIC=17 ?M), Pseudomonas aeruginosa ATCC27853 (MIC=23 ?M), Bacillus dysenteriae (MIC=40 ?M);##Yeast: Candida albicans ATCC2002 (MIC=60 ?M)."	[Ref.21816202] IC50=150 ¦ÌM against washed human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	[Ref.21816202] Cytotoxicity: the K562 (IC50=46¦ÌM)and HT29 mammalian cell lines(IC50=40¦ÌM).	Not found	21816202	Biochimie. 2012 Feb;94(2):328-334.	"Chen Z, Yang X, Liu Z, Zeng L, Lee W, Zhang Y."	"Two novel families of antimicrobial peptides from skin secretions of the Chinese torrent frog, Amolops jingdongensis."
DRAMP01869	FFPIIAGMAAKLIPSLFCKITKKC	24	"Brevinin-1SPa (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana septentrionalis (mink frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has inhibitory activity towards reference strains of bacteria and an opportunistic yeast pathogen. Also has hemolytic activity against human erythrocytes.	[Ref.15556063]Gram-negative bacterium: Escherichia coli (MIC=13 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=6 ?M);##Yeast: Candida albicans (MIC=7 ?M).	[Ref.15556063]HC50=7 ?M against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15556063	Comp Biochem Physiol C Toxicol Pharmacol. 2004 Oct;139(1-3):31-38.	"Bevier CR, Sonnevend A, Kolodziejek J, Nowotny N, Nielsen PF, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis).
DRAMP01870	FLPIIAGMAAKVICAITKKC	20	"Brevinin-1SPb (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana septentrionalis (mink frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has inhibitory activity towards reference strains of bacteria and an opportunistic yeast pathogen. Also has hemolytic activity against human erythrocytes (HC50=6 ?M).	[Ref.15556063]Gram-negative bacterium: Escherichia coli (MIC=50 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=13 ?M);##Yeast: Candida albicans (MIC=25 ?M).	[Ref.15556063]HC50=25 ?M against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15556063	Comp Biochem Physiol C Toxicol Pharmacol. 2004 Oct;139(1-3):31-38.	"Bevier CR, Sonnevend A, Kolodziejek J, Nowotny N, Nielsen PF, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis).
DRAMP01872	FFPIIAGMAAKVICAITKKC	20	"Brevinin-1SPd (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana septentrionalis (mink frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has inhibitory activity towards reference strains of bacteria and an opportunistic yeast pathogen. Also has hemolytic activity against human erythrocytes.	[Ref.15556063]Gram-negative bacterium: Escherichia coli (MIC=13 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=3 ?M);##Yeast: Candida albicans (MIC=8 ?M).	[Ref.15556063]HC50=8 ?M against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15556063	Comp Biochem Physiol C Toxicol Pharmacol. 2004 Oct;139(1-3):31-38.	"Bevier CR, Sonnevend A, Kolodziejek J, Nowotny N, Nielsen PF, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis).
DRAMP01873	GIWDTIKSMGKVFAGKILQNL	21	"Brevinin-2-related peptide (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana septentrionalis (mink frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Has inhibitory activity towards reference strains of bacteria and an opportunistic yeast pathogen. Also has hemolytic activity against human erythrocytes.
Sequence similarity: This peptide shows limited structural similarity with the N-terminal region of brevinin-2 peptides previously isolated from R. temporaria skin but lacks the C-terminal cyclic heptapeptide domain associated with this family.
PTM: C-terminal amidation."	[Ref.15556063]Gram-negative bacterium: Escherichia coli (MIC=13 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=25 ?M);##Yeast: Candida albicans (MIC=70 ?M).	[Ref.15556063]HC50=70 ?M against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15556063	Comp Biochem Physiol C Toxicol Pharmacol. 2004 Oct;139(1-3):31-38.	"Bevier CR, Sonnevend A, Kolodziejek J, Nowotny N, Nielsen PF, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis).
DRAMP01748	FFPIVGKRLYGLL	13	"Temporin-AJ8 (Frogs, amphibians, animals)"	K7Z903 	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Amolops jingdongensis (torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: Shows antimicrobial abilities against microorganisms including Gram-negative and Gram-positive bacteria, and fungi. Has hemolytic activity."	"[Ref.22828809] Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=70 ¦Ìg/ml), B. dysenteriae(MIC=18.75 ¦Ìg/ml) ;## Gram-positive bacteria: Staphylococcus aureus ATCC 2592(MIC=4.7 ¦Ìg/ml), Bacillus subtilis ATCC 6633(MIC=9.38 ¦Ìg/ml);## Yeast: Candida albicans ATCC 2002(MIC=37.5 ¦Ìg/ml)."	"[Ref.22828809] 1.79% hemolysis at 25¦Ìg/ml, 5.22% hemolysis at 50¦Ìg/ml, 7.92% hemolysis at 100¦Ìg/ml, 10.85% hemolysis at 200¦Ìg/ml against rabbit red blood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22828809	Amino Acids. 2012 Jul 25.	"He X, Yang S, Wei L, Liu R, Lai R, Rong M."	"Antimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis."
DRAMP01888	FFPTIAGLTKLFCAITKKC	19	"Brevinin-1CHc (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana chiricahuensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: E. coli (MIC=80 ?M);##Gram-positive bacterium: S. aureus (MIC=20 ?M).##Yeast: C. albicans (MIC=20 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys13 and Cys19)	Disulfide bond between Cys13 and Cys19.	L	No cytotoxicity information found	Not found	21262304	Peptides. 2011 Apr;32(4):664-669.	"Conlon JM, Mechkarska M, Coquet L, Jouenne T, Leprince J, Vaudry H, Kolodziejek J, Nowotny N, King JD."	Characterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona.
DRAMP01889	GIGSILGVIAKGLPTLISWIKNR	23	"Brevinin-1TOa (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana tagoi okiensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: E. coli (MIC=20 ?M);##Gram-positive bacterium: S. aureus (MIC=5 ?M).##Yeast: C. albicans (MIC=20 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19799928	Toxicon. 2010 Feb-Mar;55(2-3):430-435.	"Conlon JM, Coquet L, Jouenne T, Leprince J, Vaudry H, Iwamuro S."	Evidence from the primary structures of dermal antimicrobial peptides that Rana tagoi okiensis and Rana tagoi tagoi (Ranidae) are not conspecific subspecies.
DRAMP01890	FLGAIAGVAAKFLPKVFCFITKKC	24	"Brevinin-1VLa (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana vaillanti (Central American frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Brevinin-1VLa showes particularly high growth-inhibitory potency (MIC < or =3 microM) against a Gram-positive microorganism Staphylococcus aureus and the opportunistic yeast pathogen Candida albicans and potent cytolytic activity (LC(50)< or =8 microM) against both human erythrocytes and HepG2 hepatoma-derived cells. The peptide ia also active against a Gram-negative microorganism Escherichia coli (MIC< or =50 microM).	Gram-negative bacterium: E. coli (MIC=25 ?M);##Gram-positive bacterium: S. aureus (MIC=3 ?M).##Yeast: C. albicans (MIC=3 ?M).	[Ref.19379837] LC50=8 mM against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	[Ref.19379837] LC50=4mM against HepG2 hepatoma-derived cells	Not found	19379837	Comp Biochem Physiol C Toxicol Pharmacol. 2009 Aug;150(2):150-154.	"Conlon JM, Raza H, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Purification of peptides with differential cytolytic activities from the skin secretions of the Central American frog, Lithobates vaillanti (Ranidae)."
DRAMP01891	FLPVIASVAAKVLPKVFCFITKKC	24	"Brevinin-1VLc (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana vaillanti (Central American frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Brevinin-1VLc showes particularly high growth-inhibitory potency (MIC < or =3 microM) against a Gram-positive microorganism Staphylococcus aureus and the opportunistic yeast pathogen Candida albicans and potent cytolytic activity (LC(50)< or =8 microM) against both human erythrocytes and HepG2 hepatoma-derived cells. The peptide ia also active against a Gram-negative microorganism Escherichia coli (MIC< or =50 microM).	Gram-negative bacterium: E. coli (MIC=50 ?M);##Gram-positive bacterium: S. aureus (MIC=1.5 ?M).##Yeast: C. albicans (MIC=3 ?M).	[Ref.19379837] LC50=7 mM against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	[Ref.19379837] LC50=4mM against HepG2 hepatoma-derived cells	Not found	19379837	Comp Biochem Physiol C Toxicol Pharmacol. 2009 Aug;150(2):150-154.	"Conlon JM, Raza H, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Purification of peptides with differential cytolytic activities from the skin secretions of the Central American frog, Lithobates vaillanti (Ranidae)."
DRAMP01892	FLPLIAGVAANFLPKIFCLISKKC	24	"Brevinin-1VLd (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana vaillanti (Central American frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Inhibits the growth of reference strains of S. aureus, E. coli and C. albicans and to lyse human erythrocytes from a healthy donor and HepG2 human hepatoma-derived cells"	Gram-negative bacterium: E. coli (MIC>100 ?M);##Gram-positive bacterium: S. aureus (MIC=3 ?M).##Yeast: C. albicans (MIC=3 ?M).	[Ref.19379837] LC50=5 mM against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	[Ref.19379837] LC50=6mM against HepG2 hepatoma-derived cells	Not found	19379837	Comp Biochem Physiol C Toxicol Pharmacol. 2009 Aug;150(2):150-154.	"Conlon JM, Raza H, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Purification of peptides with differential cytolytic activities from the skin secretions of the Central American frog, Lithobates vaillanti (Ranidae)."
DRAMP01893	FLPLIAGVAASILPKIFCFITKKC	24	"Brevinin-1VLe (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana vaillanti (Central American frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Inhibits the growth of reference strains of S. aureus, E. coli and C. albicans and to lyse human erythrocytes from a healthy donor and HepG2 human hepatoma-derived cells"	Gram-negative bacterium: E. coli (MIC>100 ?M);##Gram-positive bacterium: S. aureus (MIC=3 ?M).##Yeast: C. albicans (MIC=3 ?M).	[Ref.19379837] LC50=5 mM against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	[Ref.19379837] LC50=7mM against HepG2 hepatoma-derived cells	Not found	19379837	Comp Biochem Physiol C Toxicol Pharmacol. 2009 Aug;150(2):150-154.	"Conlon JM, Raza H, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Purification of peptides with differential cytolytic activities from the skin secretions of the Central American frog, Lithobates vaillanti (Ranidae)."
DRAMP01896	FLSTALKVAANVVPTLFCKITKKC	24	"Brevinin-1CG1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Amolops chunganensis (Chungan torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Rhodococcus rhodochrous X15 (MIC=9 ?M), Bacillus licheniformis X39 (IS) (MIC=75 ?M);##Gram-negative bacterium: Escherichia coli (ATCC 25922) (MIC=150 ?M).##Fungi: Slime mold 090223 (IS) (MIC=75 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22951323	Peptides. 2012 Nov;38(1):41-53.	"Yang X, Xia J, Yu Z, Hu Y, Li F, Meng H, Yang S, Liu J, Wang H."	Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis.
DRAMP01897	FLPIVAGLAANFLPKIVCKITKKC	24	"Brevinin-1CG2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Amolops chunganensis (Chungan torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Rhodococcus rhodochrous X15 (MIC=9 ?M), Bacillus licheniformis X39 (IS) (MIC=75 ?M), Enterococcus faecalis 981 (MIC=19 ?M), Staphylococcus carnosus KHS (IS) (MIC=9 ?M), Staphylococcus aureus (ATCC 25923) (MIC=9 ?M);##Gram-negative bacteria: Escherichia coli (ATCC 25922) (MIC=150 ?M), Psychrobacter faecalis X29 (IS) (MIC=19 ?M), Serratia rubidaea X01 (IS) (MIC=19 ?M).##Fungi: Slime mold 090223 (IS) (MIC=4.5 ?M), Candida albicans (ATCC 10231) (MIC=150 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22951323	Peptides. 2012 Nov;38(1):41-53.	"Yang X, Xia J, Yu Z, Hu Y, Li F, Meng H, Yang S, Liu J, Wang H."	Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis.
DRAMP01898	FLSTLLNVASNVVPTLICKITKKC	24	"Brevinin-1CG3 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Amolops chunganensis (Chungan torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Primarily active against Gram-positive bacteria. Also highly active against Gram-negative P. faecalis X29 and S. rubidaea.	"Gram-positive bacteria: Rhodococcus rhodochrous X15 (MIC=2.3 ?M), Bacillus licheniformis X39 (IS) (MIC=9 ?M), Enterococcus faecalis 981 (MIC=75 ?M), Staphylococcus carnosus KHS (IS) (MIC=19 ?M), Staphylococcus aureus (ATCC 25923) (MIC=19 ?M);##Gram-negative bacteria: Escherichia coli (ATCC 25922) (MIC=150 ?M), Psychrobacter faecalis X29 (IS) (MIC=4.5 ?M), Serratia rubidaea X01 (IS) (MIC=9 ?M).##Fungi: Slime mold 090223 (IS) (MIC=9 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22951323	Peptides. 2012 Nov;38(1):41-53.	"Yang X, Xia J, Yu Z, Hu Y, Li F, Meng H, Yang S, Liu J, Wang H."	Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis.
DRAMP01899	FLSTLLNVASKVVPTLFCKITKKC	24	"Brevinin-1CG4 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Amolops chunganensis (Chungan torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Rhodococcus rhodochrous X15 (MIC=2.3 ?M), Bacillus licheniformis X39 (IS) (MIC=9 ?M), Enterococcus faecalis 981 (MIC=9 ?M), Staphylococcus carnosus KHS (IS) (MIC=9 ?M), Staphylococcus aureus (ATCC 25923) (MIC=9 ?M);##Gram-negative bacterium: Escherichia coli (ATCC 25922) (MIC=150 ?M), Pseudomonas aeruginosa 11053 (IS) (MIC=75 ?M), Psychrobacter faecalis X29 (IS) (MIC=9 ?M), Serratia rubidaea X01 (IS) (MIC=9 ?M).##Fungi: Slime mold 090223 (IS) (MIC=9 ?M), Candida albicans (ATCC 10231) (MIC=150 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22951323	Peptides. 2012 Nov;38(1):41-53.	"Yang X, Xia J, Yu Z, Hu Y, Li F, Meng H, Yang S, Liu J, Wang H."	Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis.
DRAMP01900	FLPMLAGLAANFLPKIVCKITKKC	24	"Brevinin-1CG5 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Amolops chunganensis (Chungan torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Primarily active against Gram-positive bacteria, escecially R. rhodochrous. Also highly active against Gram-negative P. faecalis X29 and S. rubidaea."	"Gram-positive bacteria: Rhodococcus rhodochrous X15 (MIC=0.6 ?M), Bacillus licheniformis X39 (IS) (MIC=2.3 ?M), Enterococcus faecalis 981 (MIC=9 ?M), Staphylococcus carnosus KHS (IS) (MIC=1.2 ?M), Staphylococcus aureus (ATCC 25923) (MIC=9 ?M);##Gram-negative bacteria: Escherichia coli (ATCC 25922) (MIC=75 ?M), Pseudomonas aeruginosa (CGMCC 1.50) (MIC=75 ?M), Pseudomonas aeruginosa 11053 (IS) (MIC=75 ?M), Klebsiella pneumoniae 08040724 (IS) (MIC=150 ?M), Psychrobacter faecalis X29 (IS) (MIC=9 ?M), Serratia rubidaea X01 (IS) (MIC=4.6 ?M).##Fungi: Slime mold 090223 (IS) (MIC=4.5 ?M), Candida albicans (ATCC 10231) (MIC=437.5 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22951323	Peptides. 2012 Nov;38(1):41-53.	"Yang X, Xia J, Yu Z, Hu Y, Li F, Meng H, Yang S, Liu J, Wang H."	Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis.
DRAMP01914	GLLDTFKNLALNAAKSAGVSVLNSLSCKLSKTC	33	"Brevinin-2GRa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana grahami (Asian frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: Escherichia coli (MIC=12.5 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=50 ?M).##Yeast: Candida albicans (MIC>100 ?M).	[Ref.16621155] LC50=140 ¦ÌM against human erythrocytes. 	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	16621155##17272268	Peptides. 2006 Sep;27(9):2111-2117.##Mol Cell Proteomics. 2007 May;6(5):882-894. 	"Conlon JM, Al-Ghaferi N, Abraham B, Jiansheng H, Cosette P, Leprince J, Jouenne T, Vaudry H.##Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	"Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami.##Anti-infection peptidomics of amphibian skin."
DRAMP01918	FLPLIAGLAANFLPKIFCAITKKC	24	"Brevinin-1PLb (Frogs, amphibians, animals)"	A7WNV3	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana palustris (Pickerel frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity.
Tissue specificity: Expressed by the skin glands."	Gram-positive bacterium: Staphylococcus aureus (MIC=9 ?M);##Gram-negative bacterium: Escherichia coli(MIC=26 ?M).##Yeast: Candida albicans (MIC=6 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17698247##11087945	Peptides. 2007 Aug;28(8):1605-1610.##Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.	"Zhou M, Wang L, Owens DE, Chen T, Walker B, Shaw C.##Basir YJ, Knoop FC, Dulka J, Conlon JM."	"Rapid identification of precursor cDNAs encoding five structural classes of antimicrobial peptides from pickerel frog (Rana palustris) skin secretion by single step shotgun cloning.##Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris."
DRAMP01919	FLPVIAGVAAKFLPKIFCAITKKC	24	"Brevinin-1PLc (Frogs, amphibians, animals)"	A7WNV4	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana palustris (Pickerel frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus (MIC=4 ?M);##Gram-negative bacterium: Escherichia coli(MIC=7 ?M).##Yeast: Candida albicans (MIC=8 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17698247##11087945	Peptides. 2007 Aug;28(8):1605-1610.##Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.	"Zhou M, Wang L, Owens DE, Chen T, Walker B, Shaw C.##Basir YJ, Knoop FC, Dulka J, Conlon JM."	"Rapid identification of precursor cDNAs encoding five structural classes of antimicrobial peptides from pickerel frog (Rana palustris) skin secretion by single step shotgun cloning.##Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris."
DRAMP01940	FLPIIAGVAAKVLPKLFCAITKKC	24	"Brevinin-1CHa (Frogs, amphibians, animals)"	A7YJE2	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana chiricahuensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	PTM: Contains disulfide bond.	"Gram-negative bacteria: E. coli (MIC=10 ?M), K. pneumoniae (MIC=40 ?M), P. aeruginosa (MIC=20 ?M);##Gram-positive bacterium: S. aureus (MIC=2.5 ?M).##Yeast: C. albicans (MIC=2.5 ?M).(Ref.2)"	[Ref.21262304] LC50=5 ?M against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	17938991##21262304	J Mol Evol. 2007 Nov;65(5):605-615.##Peptides. 2011 Apr;32(4):664-669.	"Tennessen JA, Blouin MS.##Conlon JM, Mechkarska M, Coquet L, Jouenne T, Leprince J, Vaudry H, Kolodziejek J, Nowotny N, King JD."	Selection for antimicrobial peptide diversity in frogs leads to gene duplication and low allelic variation.##Characterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona.
DRAMP01941	FLPVIAGLAAKVLPKLFCAITKKC	24	"Brevinin-1CHb (Frogs, amphibians, animals)"	A7YJE4	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana chiricahuensis 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	PTM: Contains disulfide bond.	"Gram-negative bacteria: E. coli (MIC=10 ?M), K. pneumoniae (MIC=40 ?M), P. aeruginosa (MIC=10 ?M);##Gram-positive bacterium: S. aureus (MIC=2.5 ?M).##Yeast: C. albicans (MIC=2.5 ?M).(Ref.2)"	[Ref.21262304] LC50=5 ?M against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	17938991##21262304	J Mol Evol. 2007 Nov;65(5):605-615.##Peptides. 2011 Apr;32(4):664-669.	"Tennessen JA, Blouin MS.##Conlon JM, Mechkarska M, Coquet L, Jouenne T, Leprince J, Vaudry H, Kolodziejek J, Nowotny N, King JD."	Selection for antimicrobial peptide diversity in frogs leads to gene duplication and low allelic variation.##Characterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona.
DRAMP01963	FLPAIVGAAAKFLPKIFCAISKKC	24	"Brevinin-1BLa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Lithobates blairi (plains leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Trichosporon beigelli, Aspergillus awamori, Aspergillus flavus, Aspergillus fumigatus, Aspergillus parasiticus"	[Ref.19254736] Gram-positive bacteria : Staphylococcus aureus(MIC=1.5 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=25 ¦ÌM);##Fungi : Candida albicans(MIC=6 ¦ÌM)	[Ref.19254736] LC50=14 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19254736	Toxicon. 2009 Jun;53(7-8):699-705. doi: 10.1016/j.toxicon.2009.02.018.	"Conlon JM, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis."
DRAMP01965	FLPIIAGIAAKFLPKIFCTISKKC	24	"Brevinin-1BLc (Frogs, amphibians, animals)"	B6CPR0	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Lithobates blairi (leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	[Ref.19254736]Gram-negative bacterium:?Escherichia coli (MIC=25 ?M);##Gram-positive bacterium:?Staphylococcus aureus (MIC=1.5 ?M);##Yeast:?Candida albicans (MIC=3 ?M);##Cancer cells HepG2:?(LC50=6 ?M)..	[Ref.19254736] LC50=9 ¦ÌM against human red blood cells.##[Ref.14531844]Non-hemolytic activity against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19254736	Toxicon. 2009 Jun;53(7-8):699-705. doi: 10.1016/j.toxicon.2009.02.018.	"Conlon JM, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis."
DRAMP01968	FLPIIAGAAAKVVEKIFCAISKKC	24	"Brevinin-1Yc (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Lithobates yavapaiensis (North American leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	[Ref.19254736] Gram-positive bacteria : Staphylococcus aureus(MIC=6 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=100 ¦ÌM);##Fungi : Candida albicans(MIC=6 ¦ÌM)Gram-negative bacterium: Escherichia coli (MIC=100 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=6 ?M).##Yeast: Candida albicans (MIC=6 ?M).##cancer cells HepG2 (LC50=14 ?M). 	[Ref.19254736] LC50=13 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19254736	Toxicon. 2009 Jun;53(7-8):699-705. doi: 10.1016/j.toxicon.2009.02.018.	"Conlon JM, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis."
DRAMP01970	FLPFLLSALPKVFCFFSKKC	20	"Brevinin-1ZHa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana zhenhaiensis (Chinese brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=8 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=16 ?M), Pseudomonas aeruginosa ATCC 9027 (MIC=32 ?M).##Yeast: Candida albicans ATCC 2002 (MIC>43 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22943778	Zoolog Sci. 2012 Sep;29(9):553-558.	"Xu B, Che H, Kang L, Zheng S, Mu S, Wan F."	"Molecular Cloning and Functional Characterization of Novel Antimicrobial Peptides from the Skin of Brown Frog, Rana zhenhaiensis."
DRAMP01971	FLPLLLSALPSFLCLVFKKC	20	"Brevinin-1ZHb (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana zhenhaiensis (Chinese brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=17 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=33 ?M), Pseudomonas aeruginosa ATCC 9027 (MIC>44 ?M).##Yeast: Candida albicans ATCC 2002 (MIC>44 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22943778	Zoolog Sci. 2012 Sep;29(9):553-558.	"Xu B, Che H, Kang L, Zheng S, Mu S, Wan F."	"Molecular Cloning and Functional Characterization of Novel Antimicrobial Peptides from the Skin of Brown Frog, Rana zhenhaiensis."
DRAMP01974	GIMRVFKGVLKTAGKSVAKNVAGSFLDRLKCKISGGC	37	"Brevinin-2ZHa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana zhenhaiensis (Chinese brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=1 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5 ?M), Pseudomonas aeruginosa ATCC 9027 (MIC=5 ?M).##Yeast: Candida albicans ATCC 2002 (MIC=3 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22943778	Zoolog Sci. 2012 Sep;29(9):553-558.	"Xu B, Che H, Kang L, Zheng S, Mu S, Wan F."	"Molecular Cloning and Functional Characterization of Novel Antimicrobial Peptides from the Skin of Brown Frog, Rana zhenhaiensis."
DRAMP01986	SLLGTVKDLLIGAGKSAAQSVLKGLSCKLSKDC	33	"Brevinin-2HS2 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Huia schmackeri (Chinese piebald odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: It shows poor hemolycity activity (LC50=300 uM). 	"Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=19 ?M), Bacillus licheniformis X39 (MIC=39 ?M), Rhodococcus rhodochrous X15 (MIC=9.5 ?M);##Gram-negative bacterium: Psychrobacter faecalis X29 (MIC=9.5 ?M).##Fungi: Slime mould 090223 (MIC=37.5 ?M), Candida albicans ATCC2002 (MIC=19 ?M)."	LC50=300?M against human erythrocytes	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	18423796	Peptides. 2008 Aug;29(8):1456-1460.	"Quan Z, Zhou M, Chen W, Chen T, Walker B, Shaw C."	Novel brevinins from Chinese piebald odorous frog (Huia schmackeri) skin deduced from cloned biosynthetic precursors.
DRAMP01995	SFLTTFKDLAIKAAKSAGQSVLSTLSCKLSNTC	33	"Brevinin-2ISb (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana ishikawae (Endangered frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial activity.	"Gram-negative bacterium: Escherichia coli (MIC=12.5 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=6.3 ?M), Bacillus subtilis (MIC=25 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21193000	Peptides. 2011 Apr;32(4):670-676. 	"Iwakoshi-Ukena E, Ukena K, Okimoto A, Soga M, Okada G, Sano N, Fujii T, Sugawara Y, Sumida M."	Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae.
DRAMP02001	FLPLIASLAANFVPKIFCKITKKC	24	"Brevinin-1HN1 (Frogs, amphibians, animals)"	E7EKC4	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana hainanensis (Hainan odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacteria and fungi but has weak or no activity against a range of Gram-negative bacteria except P. faecalis. Has hemolytic activity against human erythrocytes (LC50=75 ?M).

Tissue specificity: Expressed by the skin glands.

PTM: Contains one disulfide bond."	"[Ref.22450466]Gram-positive bacteria: Enterococcus faecium 091299 (MIC=19 ?M), Enterococcus faecalis 981 (MIC=19 ?M), Staphylococcus aureus ATCC2592 (MIC=1.2 ?M), Staphylococcus carnosus KHS (MIC=4.8 ?M), Bacillus licheniformis X39 (MIC=2.4 ?M), Rhodococcus rhodochrous X15 (MIC=1.2 ?M);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=150 ?M), Psychrobacter faecalis X29 (MIC=4.8 ?M);##Fungi: Slime mould 090223 (MIC=1.2 ?M), Candida albicans ATCC2002 (MIC=2.4 ?M)."	[Ref.22450466] LC50=75 ?M against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22450466	Peptides. 2012 Jun;35(2):285-290.	"Wang H, Yu Z, Hu Y, Li F, Liu L, Zheng H, Meng H, Yang S, Yang X, Liu J."	"Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis."
DRAMP02004	FLPLIASVAANLVPKIFCKITKKC	24	"Brevinin-1V (Frogs, amphibians, animals)"	"Q2UXV8, E7EKC5"	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana versabilis (Chinese bamboo leaf odorous frog) (Rana versabilis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacteria and fungi but has weak or no activity against a range of Gram-negative bacteria except P. faecalis. Has hemolytic activity against human erythrocytes.
Tissue specificity: Expressed by the skin glands.
PTM: Contains one disulfide bond."	"[Ref.22450466]Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=19 ?M), Bacillus licheniformis X39 (MIC=37.5 ?M), Rhodococcus rhodochrous X15 (MIC=9.5 ?M), Enterococcus faecium 091299 (MIC=19 ?M), E. faecalis 981 (MIC=19 ?M);##Gram-negative bacterium: Psychrobacter faecalis X29 (MIC=9.5 ?M);##Fungi: Slime mould 090223 (MIC=1.2 ?M), Candida albicans ATCC2002 (MIC=19-37.5 ?M)."	[Ref.22450466] LC50=75 ?M against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	16139929##22450466	Peptides. 2006 Jan;27(1):42-48.##Peptides. 2012 Jun;35(2):285-290.	"Chen T, Li L, Zhou M, Rao P, Walker B, Shaw C.##Wang H, Yu Z, Hu Y, Li F, Liu L, Zheng H, Meng H, Yang S, Yang X, Liu J."	"Amphibian skin peptides and their corresponding cDNAs from single lyophilized secretion samples: identification of novel brevinins from three species of Chinese frogs.##Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis."
DRAMP18380	SGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAQRVGAGAPVY	50	Acipensin 1 (Ac1)	No entry found	Not found	Not found	"Leukocytes; the Russian Sturgeon, Acipenser gueldenstaedtii"	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against E. coli ML35p (MIC 0.7 uM), L. monocytogenes EGD (MIC 1.1 uM), MRSA ATCC 33591 (MIC 0.9 uM), C. albicans 820 (MIC 1 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	25558400	Acta Naturae. 2014 Oct;6(4):99-109	"Shamova OV, Orlov DS, Balandin SV, Shramova EI, Tsvetkova EV, Panteleev PV, Leonova YF, Tagaev AA, Kokryakov VN, Ovchinnikova TV."	Acipensins - Novel Antimicrobial Peptides from Leukocytes of the Russian Sturgeon Acipenser gueldenstaedtii
DRAMP18379	SGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLR	35	Acipensin 2 (Ac2)	No entry found	Not found	Not found	"Leukocytes; the Russian Sturgeon, Acipenser gueldenstaedtii"	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against E. coli ML35p (MIC 0.3 uM), L. monocytogenes EGD (MIC 1.0 uM), MRSA ATCC 33591 (MIC 0.6 uM), C. albicans 820 (MIC 0.9 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	25558400	Acta Naturae. 2014 Oct;6(4):99-109.	"Shamova OV, Orlov DS, Balandin SV, Shramova EI, Tsvetkova EV, Panteleev PV, Leonova YF, Tagaev AA, Kokryakov VN, Ovchinnikova TV."	Acipensins - Novel Antimicrobial Peptides from Leukocytes of the Russian Sturgeon Acipenser gueldenstaedtii.
DRAMP02032	FLGSIVGALASALPSLISKIRN	22	"Brevinin-1TSa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana tsushimensis (Tsushima brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Activity against a range of Gram-positive and Gram-negative bacteria, but hemolytic activity against human erythrocytes."	"[Ref.16413829]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=25 ?M), Klebsiella pneumoniae KK3 9904 (MIC>100 ?M), Enterobacter cloacae HNTCC 53001 (MIC=50 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=50 ?M), Proteus mirabilis ATCC 25933 (MIC>100 ?M);##Gram-positive bacteria: Staphylococcus aureus NCTC 8325 (MIC=25 ?M), Methicillin-resistant Staphylococcus aureus T7/20 (MIC=25 ?M), Staphylococcus epidermidis RP62A (MIC=12.5 ?M), Enterococcus faecalis ATCC 29212 (MIC=50 ?M), Streptococcus group B HNTCC 80130 (MIC=50 ?M);##Yeast: Candida albicans ATCC 90028 (MIC=50 ?M)"	[Ref.16413829]LD50=12 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16413829	Comp Biochem Physiol C Toxicol Pharmacol. 2006 May;143(1):42-49. 	"Conlon JM, Al-Ghaferi N, Abraham B, Sonnevend A, Coquet L, Leprince J, Jouenne T, Vaudry H, Iwamuro S."	Antimicrobial peptides from the skin of the Tsushima brown frog Rana tsushimensis.
DRAMP02033	GIMSLFKGVLKTAGKHVAGSLVDQLKCKITGGC	33	"Brevinin-2TSa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana tsushimensis (Tsushima brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Activity against a range of Gram-positive and Gram-negative bacteria, but relatively low hemolytic activity against human erythrocytes."	"[Ref.16413829]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3 ?M), Klebsiella pneumoniae KK3 9904 (MIC=6 ?M), Enterobacter cloacae HNTCC 53001 (MIC=6 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=6 ?M), Proteus mirabilis ATCC 25933 (MIC>100 ?M);##Gram-positive bacteria: Staphylococcus aureus NCTC 8325 (MIC=12.5 ?M), Methicillin-resistant Staphylococcus aureus T7/20 (MIC=25 ?M), Staphylococcus epidermidis RP62A (MIC=12.5 ?M), Enterococcus faecalis ATCC 29212 (MIC=25 ?M);##Yeast: Candida albicans ATCC 90028 (MIC=100 ?M)."	[Ref.16413829] LD50=100 ¦ÌM against human erythrocytes	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	16413829	Comp Biochem Physiol C Toxicol Pharmacol. 2006 May;143(1):42-49. 	"Conlon JM, Al-Ghaferi N, Abraham B, Sonnevend A, Coquet L, Leprince J, Jouenne T, Vaudry H, Iwamuro S."	Antimicrobial peptides from the skin of the Tsushima brown frog Rana tsushimensis.
DRAMP02034	FLPILAGLAAKLVPKVFCSITKKC	24	"Brevinin-1AUa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana aurora aurora (Northern red-legged frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Activity against a range of Gram-positive and Gram-negative bacteria, and also shows hemolytic. "	"[Ref.15325526]Gram-negative bacteria: Escherichia coli (MIC=13 ?M), Pseudomonas aeruginosa (MIC=25 ?M), Enterobacter cloacae (MIC=13 ?M), Klebsiella pneumoniae (MIC=50 ?M), Proteus mirabilis (MIC>50 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=3 ?M), Staphylococcus epidermidis (MIC=6 ?M), Enterococcus faecalis (MIC=13 ?M), Streptococcus Group B (MIC=13 ?M);##Yeast: Candida albicans (MIC>40 ?M)."	[Ref.15325526] HC50=5 ¦ÌM against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	15325526	Dev Comp Immunol. 2005;29(1):83-90.	"Conlon JM, Sonnevend A, Davidson C, Demandt A, Jouenne T."	Host-defense peptides isolated from the skin secretions of the Northern red-legged frog Rana aurora aurora.
DRAMP02035	FLPILAGLAANILPKVFCSITKKC	24	"Brevinin-1AUb (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana aurora aurora (Northern red-legged frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Activity against a range of Gram-positive and Gram-negative bacteria, and also shows hemolytic activity. "	"[Ref.15325526]Gram-negative bacteria: Escherichia coli (MIC=25 ?M), Pseudomonas aeruginosa (MIC=25 ?M), Enterobacter cloacae (MIC=25 ?M), Klebsiella pneumoniae (MIC>50 ?M), Proteus mirabilis (MIC>50 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=3 ?M), Staphylococcus epidermidis (MIC=6 ?M), Enterococcus faecalis (MIC=6 ?M), Streptococcus Group B (MIC=13 ?M);##Yeast: Candida albicans (MIC=3 ?M)."	[Ref.15325526] HC50=7 ¦ÌM against human erythrocytes	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	15325526	Dev Comp Immunol. 2005;29(1):83-90.	"Conlon JM, Sonnevend A, Davidson C, Demandt A, Jouenne T."	Host-defense peptides isolated from the skin secretions of the Northern red-legged frog Rana aurora aurora.
DRAMP02036	GAFGNFLKGVAKKAGLKILSIAQCKLSGTC	30	"Brevinin-2-RN1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana nigrovittata	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Brevinin-2-RN1 and -RN2 could induce 17 and 21% Rabbit red blood cell hemolysis, respectively."	"Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=3.10 ?g/ml), Staphylococcus aureus ATCC43300 (MIC=3.10 ?g/ml), Bacillus subtilis (MIC=12.5 ?g/ml);##Gram-negative bacteria: Escherichia coli ML-35P (MIC=25 ?g/ml), Pseudomonas aeruginosa PA01 (MIC=12.5 ?g/ml), Pseudomonas aeruginosa ATCC27853 (MIC=25 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=6.25 ?g/ml)."	[Ref.21171145] It has 17% hemolysis at 100 ?g/ml against rabbit red blood cell	Cyclic	Free	Cyclization (Cys24 and Cys30)	Disulfide bond between Cys24 and Cys30.	L	No cytotoxicity information found	Not found	21171145	J Pept Sci. 2011 Jan;17(1):68-72.	"Liu X, Liu R, Wei L, Yang H, Zhang K, Liu J, Lai R."	"Two novel antimicrobial peptides from skin secretions of the frog, Rana nigrovittata."
DRAMP02037	GAFGNFLKGVAKKAGLKILSIAQCKLFGTC	30	"Brevinin-2-RN2 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana nigrovittata	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Brevinin-2-RN1 and -RN2 could induce 17 and 21% Rabbit red blood cell hemolysis, respectively."	"Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=6.25 ?g/ml), Staphylococcus aureus ATCC43300 (MIC=6.25 ?g/ml), Bacillus subtilis (MIC=12.5 ?g/ml);##Gram-negative bacteria: Escherichia coli ML-35P (MIC=50 ?g/ml), Pseudomonas aeruginosa PA01 (MIC=12.5 ?g/ml), Pseudomonas aeruginosa ATCC27853 (MIC=12.5 ?g/ml). Yeast: Candida albicans ATCC2002 (MIC=3.1 ?g/m)."	[Ref.21171145] It has 21% hemolysis at 100 ?g/ml against rabbit red blood cell	Cyclic	Free	Cyclization (Cys24 and Cys30)	Disulfide bond between Cys24 and Cys30.	L	No cytotoxicity information found	Not found	21171145	J Pept Sci. 2011 Jan;17(1):68-72.	"Liu X, Liu R, Wei L, Yang H, Zhang K, Liu J, Lai R."	"Two novel antimicrobial peptides from skin secretions of the frog, Rana nigrovittata."
DRAMP02038	VIVFVASVAAEMMQHVYCAASKKC	24	"Brevinin-1-OA1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=12.4 ?g/ml);##Gram-negative bacteria: Bacillus pyocyaneus CMCCB 10104 (MIC=12.4 ?g/ml), Escherichia coli ATCC 25922 (MIC=6.2 ?g/ml).##Yeast: Candida albicans (MIC=24.8 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02040	FLPAVIRVAANVLPTAFCAISKKC	24	"Brevinin-1-OA12 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6.6 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.6 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=13.2 ?g/ml).##Yeast: Candida albicans (MIC=3.3 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02041	LPFVAGVAAEMMQHVYCAASKKC	23	"Brevinin-1-OR1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.3 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=42.4 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=10.6 ?g/ml).##Yeast: Candida albicans (MIC=10.6 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys17 and Cys23)	Disulfide bond between Cys17 and Cys23.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02042	IDPFVAGVAAEMMQHVYCAASKKC	24	"Brevinin-1-OR3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=9.1 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=18.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=18.2 ?g/ml).##Yeast: Candida albicans (MIC=18.2 ?g/ml). "	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02043	INPFVAGVAAEMMQHVYCAASKKC	24	"Brevinin-1-OR4 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=8.6 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=8.6 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=8.6 ?g/ml).##Yeast: Candida albicans (MIC=8.6 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02044	ILPFVAGVAAEMMKHVYCAASKKC	24	"Brevinin-1-OR5 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	It differs from AP1824 only at position 14: Q vs. K.	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=15.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=30.4 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=15.2 ?g/ml).##Yeast: Candida albicans (MIC=7.6 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02045	IIPFVAGVAAEMMEHVYCAASKKC	24	"Brevinin-1-OR6 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	It differs from AP1827 at two positions: 2: I vs. L and 14: K vs. E.	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=11.1 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=22.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=22.2 ?g/ml).##Yeast: Candida albicans (MIC=11.1 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02046	QLPFVAGVACEMCQCVYCAASKKC	24	"Brevinin-1-OR7 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.7 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=5.7 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=11.4 ?g/ml).##Yeast: Candida albicans (MIC=11.4 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02047	ILPFVAGVAAEMMEHVYCAASKKC	24	"Brevinin-1-OR8 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=13.1 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=52.4 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=26.2 ?g/ml).##Yeast: Candida albicans (MIC=13.1 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02048	ILPFVAGVAAMEMEHVYCAASKKC	24	"Brevinin-1-OR9 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=9.8 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=9.8 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=4.9 ?g/ml).##Yeast: Candida albicans (MIC=9.8 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02049	FLPAVLLVATHVLPTVFCAITRKC	24	"Brevinin-1-OR10 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3.4 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=27.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6.8 ?g/ml).##Yeast: Candida albicans (MIC=6.8 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02050	LAFVAGVAAEMMQHVYCAASKKC	23	"Brevinin-1-OR11 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=12.4 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=12.4 ?g/ml).##Yeast: Candida albicans (MIC=12.4 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys17 and Cys23)	Disulfide bond between Cys17 and Cys23.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02051	ILPFVAGVAAEMMQHVYCAASKKC	24	"Lividin-1 (Brevinin-1-OR2; Frogs, amphibians, animals)"	Q2UXR4	Belongs to the frog skin active peptide family (Brevinin subfamily)	lividin-1	Odorrana rotodora (Chinese odorous frog) (Odorrana livida)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	"Function: Amphibian defensive peptide.
Tissue specificity: Expressed by the skin glands.
PTM: Contains disulfide bond."	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.8 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=11.6 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=11.6 ?g/ml).##Yeast: Candida albicans (MIC=5.8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	16713657##22029824	Peptides. 2006 Sep;27(9):2118-2123.##J Proteome Res. 2012 Jan 1;11(1):306-319.	"Zhou M, Chen T, Walker B, Shaw C.##Yang X, Lee WH, Zhang Y."	"Lividins: novel antimicrobial peptide homologs from the skin secretion of the Chinese Large Odorous frog, Rana (Odorrana) livida. Identification by shotgun cDNA cloning and sequence analysis.##Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs."
DRAMP02052	SFLDTLKNLAISAAKGAGQSVLSTLSCKLSKTC	33	"Lividin-2 (Brevinin-2-OR8; Frogs, amphibians, animals)"	Q2UXR3	Belongs to the frog skin active peptide family (Brevinin subfamily)	lividin-2	Odorrana rotodora (Chinese odorous frog) (Odorrana livida)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	"Function: Amphibian defensive peptide.
Tissue specificity: Expressed by the skin glands.
PTM: Contains disulfide bond."	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=13.1 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=13.1 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=13.1 ?g/ml).##Yeast: Candida albicans (MIC=13.1 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	16713657##22029824	Peptides. 2006 Sep;27(9):2118-2123.##J Proteome Res. 2012 Jan 1;11(1):306-319.	"Zhou M, Chen T, Walker B, Shaw C.##Yang X, Lee WH, Zhang Y."	"Lividins: novel antimicrobial peptide homologs from the skin secretion of the Chinese Large Odorous frog, Rana (Odorrana) livida. Identification by shotgun cDNA cloning and sequence analysis.##Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs."
DRAMP02053	SVLGTVKDLLIGAGKSAAQSVLTALSCKLSNSC	33	"Lividin-3 (Brevinin-2-OR1; Frogs, amphibians, animals)"	Q2UXR2	Belongs to the frog skin active peptide family (Brevinin subfamily)	lividin-3	Odorrana rotodora (Chinese odorous frog) (Odorrana livida)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	"Function: Amphibian defensive peptide.
Tissue specificity: Expressed by the skin glands.
PTM: Contains disulfide bond."	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.5 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=22 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=11 ?g/ml).##Yeast: Candida albicans (MIC=11 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	16713657##22029824	Peptides. 2006 Sep;27(9):2118-2123.##J Proteome Res. 2012 Jan 1;11(1):306-319.	"Zhou M, Chen T, Walker B, Shaw C.##Yang X, Lee WH, Zhang Y."	"Lividins: novel antimicrobial peptide homologs from the skin secretion of the Chinese Large Odorous frog, Rana (Odorrana) livida. Identification by shotgun cDNA cloning and sequence analysis.##Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs."
DRAMP02054	GILDTFKNMALNAAKSAGVSVLNALSCKLSKTC	33	"Brevinin-2-OA1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=12.1 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=12.1 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=12.1 ?g/ml).##Yeast: Candida albicans (MIC=6.0 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02055	GLLDTFKNMALNAAKSAGVSVLNALSCKLSKTC	33	"Brevinin-2-OA2 (Brevinin-2E-OG1; Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Found in multiple species.	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=13.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=6.6 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6.6 ?g/ml).##Yeast: Candida albicans (MIC=6.6 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02056	GLLDTFKNMAINAAHGAGVSVLNALSCKLKKTC	33	"Brevinin-2-OA3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.3 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=12.6 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=6.3 ?g/ml).##Yeast: Candida albicans (MIC=3.2 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02057	GLLDTFKNLAINAAESAGVSVLNSLSCKLSKTC	33	"Brevinin-2-OA4 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=20 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=20 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=10 ?g/ml).##Yeast: Candida albicans (MIC=10 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02058	GLLDGILNANFNAAKSAGTSVLNALSCKLSKTC	33	"Brevinin-2-OA5 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30.6 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=30.6 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=30.6 ?g/ml).##Yeast: Candida albicans (MIC=30.6 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02059	GVLATVKNLLIGTGDGAAQSVLKTLSCKLSNDC	33	"Brevinin-2-OA6 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=11.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=44.8 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=22.4 ?g/ml).##Yeast: Candida albicans (MIC=11.2 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02060	GVLGTVKDLLIGAGKSAAQSTLKTLSCKISNDC	33	"Brevinin-2-OA7 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.8 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=23.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=11.6 ?g/ml).##Yeast: Candida albicans (MIC=5.8 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02061	GVLATVKNLLNGTGDGAAQSVLKTLSCKLSNDC	33	"Brevinin-2-OA8 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=7.9 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=15.8 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=4.0 ?g/ml).##Yeast: Candida albicans (MIC=4.0 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02062	GLLDTIKNMALNAAKSAGVSVLNSLSCKLSKTC	33	"Brevinin-2-OR2 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=12.1 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=6.0 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=12.1 ?g/ml).##Yeast: Candida albicans (MIC=12.1 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02063	GLIDTIKNMALNAAKSAGVSVLNTLSCKLSKTC	33	"Brevinin-2-OR3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=20.6 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=41.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=20.6 ?g/ml).##Yeast: Candida albicans (MIC=10.3 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02064	SVLGTVKDLLIGAGKSAAQSVLTANSCKLSNSC	33	"Brevinin-2-OR4 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=11.8 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=11.8 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=5.9 ?g/ml).##Yeast: Candida albicans (MIC=11.8 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02065	SFLDTLKNLAISAAKGAGQSVLSTLSCKLSETC	33	"Brevinin-2-OR5 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=13.2 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=6.6 ?g/ml).##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=6.6 ?g/ml).##Fungi: Candida albicans (MIC=6.6 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02066	GLLDTIKNMALNAAKSAGVSVLNSLSCKDSKTC	33	"Brevinin-2-OR6 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.8 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=11.6 ?g/ml).##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=5.8 ?g/ml).##Fungi: Candida albicans (MIC=11.6 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02067	GLLDTIKNMALNAAKSAGVSVLNTLSCKLSKTC	33	"Brevinin-2-OR7 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=8.6 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=8.6 ?g/ml).##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=8.6 ?g/ml).##Fungi: Candida albicans (MIC=17.2 ?g/ml)"	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02068	SFLSTFKELAINAAKNAGQSILHTLSCKLDKTC	33	"Brevinin-2-OR9 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=20.4 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=20.4 ?g/ml).##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=10.2 ?g/ml).##Fungi: Candida albicans (MIC=5.1 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02069	SFLSTFKELAINAAKNAGQSLLHTLSCKLDKTC	33	"Brevinin-2-OR10 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: It differs from AP1850 only at position 21: L vs. I, so they are predicted to have essentially identical structure and activity."	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=15.8 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=7.9 ?g/ml).##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=7.9 ?g/ml).##Fungi: Candida albicans (MIC=15.8 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02070	SVMGTVKDLLIGAGKSAAQSVLKSLSCKISNDC	33	"Brevinin-2-OW1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana wuchuanensis (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=4.7 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=4.7 ?g/ml).##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=9.4 ?g/ml).##Fungi: Candida albicans (MIC=4.7 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02071	SVMGTVKDLLIGAGKSAAQSVLKSLSCKLSNDC	33	"Brevinin-2-OW2 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana wuchuanensis (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.6 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=6.6 ?g/ml).##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=3.3 ?g/ml).##Fungi: Candida albicans (MIC=3.3 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02072	SVMGTVKDLLIGAGKSAAQSVLKALSCKLSKDC	33	"Brevinin-2-OW3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana wuchuanensis (Chinese odorous frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial and antifungal activity. 	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=10.5 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=21.0 ?g/ml).##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=10.5 ?g/ml).##Fungi: Candida albicans (MIC=10.5 ?g/ml)."	[Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 ¦Ìg/mL.	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319. 	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP02073	FLPAVIRVAANVLPTVFCAISKKC	24	"Brevinin-1JDa (Frogs, amphibians, animals)"	B3A0M4	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana jingdongensis (Jingdong frog) (Rana jingdongensis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antibacterial and antifungal activity. Has hemolytic activity against rabbit erythrocytes.
Tissue specificity: Expressed by the skin glands.
PTM: contains one disulfide bonds."	"[Ref.22917879]Gram-positive bacteria: Staphylococcus aureus (MIC=16 ?g/ml), S. aureus (MRSA) (MIC=32 ?g/ml);##Gram-negative bacterium: Escherichia coli (MIC=128 ?g/ml);##Fungi: Candida albicans (MIC=128 ?g/ml)."	[Ref.22917879] It has 79.2 ¡À 6.8% hemolytic activity at 128 ¦Ìg/mL against rabbit red blood cells	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	22917879	J Proteomics. 2012 Oct 22;75(18):5807-5821.	"Liu J, Jiang J, Wu Z, Xie F."	"Antimicrobial peptides from the skin of the Asian frog, Odorrana jingdongensis: De novo sequencing and analysis of tandem mass spectrometry data."
DRAMP02084	GIMDTLKNLAKTAGKGALQSLLNKASCKLSGQC	33	"Brevinin-2E (Frogs, amphibians, animals)"	P32413	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana esculenta (Edible frog) (Pelophylax esculentus)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity."	"[Ref.8508915]Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=0.2 ?M), Staphylococcus aureus Cowan 1 (MIC=2.0 ?M);##Gram-negative bacteria: Escherichia coli D21 (MIC=0.5 ?M), Pseudomonas aeruginosa ATCC 15692 (MIC>30 ?M)."	[Ref.8163497]LC50>100 ¦ÌM against human red blood cells	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	8508915	FEBS Lett. 1993 Jun 14;324(2):159-161.	"Simmaco M, Mignogna G, Barra D, Bossa F."	Novel antimicrobial peptides from skin secretion of the European frog Rana esculenta.
DRAMP02104	GLMSTLKDFGKTAAKEIAQSLLSTASCKLAKTC	33	"Brevinin-2RTa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Amolops ricketti (Chinese sucker frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Brevinin-2RTb has antibacterial activity and hemolytic activity against rabbit red blood cells in vitro.
PTM: Contains one disulfide bond 27-33."	"[Ref.22100518]Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=12.5 ?g/ml), Bacillus licheniformis X39 (MIC=50.0 ?g/ml), Staphylococcus carnosus KHS (MIC=6.3 ?g/ml), Rhodococcus rhodochrous X15 (MIC=1.6 ?g/ml);##Gram-negative bacteria: Serratia rubidaea X01 (MIC=100.0 ?g/ml), Psychrobacter faecalis X29 (MIC=6.3 ?g/ml)."	[Ref.22100518]LD50>400 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22100518	Peptides. 2012 Jan;33(1):27-34.	"Wang H, Ran R, Yu H, Yu Z, Hu Y, Zheng H, Wang D, Yang F, Liu R, Liu J."	Identification and characterization of antimicrobial peptides from skin of Amolops ricketti (Anura: Ranidae).
DRAMP02125	IFGAILPLALGALKNLIK	18	"Hylin-a1 (Hy-a1; Frogs, amphibians, animals)"	P85982	Not found	Not found	Hypsiboas albopunctatus (Spotted tree frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	2N0O resolved by NMR.	"Function: Has antibacterial activity against the Gram-positive bacteria and the Gram-negative bacteria. Has hemolytic activity against human erythrocytes.
Tissue specificity: Expressed by the skin glands."	"[Ref.19056441]Gram-positive bacteria: Staphylococcus aureus ATCC 25926 (MIC=8 ?M), Enterococcus faecalis ATCC 29212 (MIC=16 ?M), Bacillus subtilis ATCC 19659 (MIC=8 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=32 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=64 ?M);##Fungi: Candida albicans ATCC 90028 (MIC=16.7 ?M), C. krusei ATCC 6258 (MIC=16.7 ?M), C. parapsilosis ATCC 22019 (MIC=67 ?M), Cryptococcus neoformans ATCC 90012 (MIC=33.5 ?M)"	[Ref.19056441]HC50=18 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19056441	Peptides. 2009 Feb;30(2):291-296.	"Castro MS, Ferreira TC, Cilli EM, Crusca E Jr, Mendes-Giannini MJ, Sebben A, Ricart CA, Sousa MV, Fontes W."	"Hylin a1, the first cytolytic peptide isolated from the arboreal South American frog Hypsiboas albopunctatus (spotted treefrog)."
DRAMP02128	FLGGILNTITGLL	13	"Kassorin-S (PreproKassorin-S; Frogs, amphibians, animals)"	E6ZBE2	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Kassina senegalensis (Senegal running frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide. Has antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Lacks ability to induce contraction of smooth muscle in isolated guinea pig urinary bladder. Elicits histamine release from rat peritoneal mast cells.
Tissue specificity: Expressed by the skin glands.
PTM: C-terminal amidation."	Gram-positive bacterium: Staphylococcus aureus (MIC=30 ?M).##Yeast: Candida albicans (MIC=100 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21040978	Mol Immunol. 2011 Jan;48(4):442-451.	"Chen H, Wang L, Zeller M, Hornshaw M, Wu Y, Zhou M, Li J, Hang X, Cai J, Chen T, Shaw C."	"Kassorins: novel innate immune system peptides from skin secretions of the African hyperoliid frogs, Kassina maculata and Kassina senegalensis."
DRAMP02130	GFLGPLLKLAAKGVAKVIPHLIPSRQQ	27	"Antimicrobial peptide 1 (XT-1; Frogs, amphibians, animals)"	P84387	Not found	Not found	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E.coli and stronger activity against yeast C. albicans. Enhances the antibacterial activity of XT3. Has hemolytic activity against human red blood cells .
Tissue specificity: Expressed by the skin glands."	[Ref.11738090]Gram-positive bacteria: Staphylococcus aureus (MIC=5 ?M);##Gram-negative bacteria: Escherichia coli (MIC=6 ?M);##Fungi: Candida albicans (MIC=50 ?M)	[Ref.11738090]HC50=90 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11738090	Biochim Biophys Acta. 2001 Nov 26;1550(1):81-89.	"Ali MF, Soto A, Knoop FC, Conlon JM."	"Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae)."
DRAMP02133	GVFLDALKKFAKGGMNAVLNPK	22	"Antimicrobial peptide 4 (XT-4; Frogs, amphibians, animals)"	P84384	Not found	Not found	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacterium S. aureus and yeast C. albicans, and very weak activity against Gram-negative bacterium E.coli. Has strong hemolytic activity against human red blood cells.
Tissue specificity: Expressed by the skin glands."	[Ref.11738090]Gram-positive bacteria: Staphylococcus aureus (MIC>100 ?M);##Gram-negative bacteria: Escherichia coli (MIC=18 ?M);##Fungi: Candida albicans (MIC>100 ?M).	[Ref.11738090]HC50>150 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	11738090	Biochim Biophys Acta. 2001 Nov 26;1550(1):81-89.	"Ali MF, Soto A, Knoop FC, Conlon JM."	"Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae)."
DRAMP02135	GFLGSLLKTGLKVGSNLL	18	"Antimicrobial peptide 6 (XT-6; Frogs, amphibians, animals)"	P84386	Not found	Not found	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E.coli and strong activity against yeast C. albicans. Enhances the antibacterial activity of XT3. Has hemolytic activity against human red blood cells.
Tissue specificity: Expressed by the skin glands."	"[Ref.11738090]Gram-positive bacterium: Staphylococcus aureus (MIC=5 ?M);##Gram-negative bacterium: Escherichia coli (MIC=5 ?M);##Yeast: Candida albicans (MIC=40 ?M);##Clinical isolates: Staphylococcus aureus 8325 (MIC=6 ?M), Staphylococcus aureus (MRSA) (MIC=7 ?M), Staphylococcus epidermidis 1420129 (MIC=3 ?M), S. saprophyticus 1950556 (MIC=13 ?M), Escherichia coli 25922 (MIC=6 ?M), Streptococcus group C 1541035 (MIC=3 ?M), Shigella sonnei 1840187 (MIC=35 ?M), Pseudomonas aeruginosa 0380972 (MIC=60 ?M), Enterobacter cloacae 1441323 (MIC=35 ?M)"	[Ref.11738090]HC50=70 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	11738090	Biochim Biophys Acta. 2001 Nov 26;1550(1):81-89.	"Ali MF, Soto A, Knoop FC, Conlon JM."	"Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae)."
DRAMP02136	GLLGPLLKIAAKVGSNLL	18	"Antimicrobial peptide 7 (XT-7; Frogs, amphibians, animals)"	P84381	Not found	Not found	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Has very strong antibacterial activity against many Gram-negative bacteria and the Gram-positive bacteria S.pneumoniae and Enterococcus sp. There is moderate antimicrobial activity against the Gram-negative bacterium P.aeruginosa and yeast C. albicans and weaker activity against the Streptococcal strains and E.coli. Has hemolytic activity against human red blood cells (HC50=70 ?M). Seems to disrupt the membranes by adopting an alpha-helical conformation.
Tissue specificity: Expressed by the skin glands.
PTM: Amidation on Leu-18 is required to adopt an alpha-helical conformation in a hydrophobic solvent. The absence of amidation leads to a decrease in cationicity leading to a more than a 10-fold decrease in antimicrobial activities."	"Gram-positive bacterium: Staphylococcus aureus (MIC=5 ?M);##Gram-negative bacterium: Escherichia coli (MIC=5 ?M);##yeast Candida albicans (MIC=40 ?M).##Clinical isolates: Staphylococcus aureus 8325 (MIC=6 ?M), Staphylococcus aureus (MRSA) (MIC=7 ?M), Staphylococcus epidermidis 1420129 (MIC=3 ?M), S. saprophyticus 1950556 (MIC=13 ?M), Escherichia coli 25922 (MIC=6 ?M), Streptococcus group C 1541035 (MIC=3 ?M), Shigella sonnei 1840187 (MIC=35 ?M), Pseudomonas aeruginosa 0380972 (MIC=60 ?M), Enterobacter cloacae 1441323 (MIC=35 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	11738090	Biochim Biophys Acta. 2001 Nov 26;1550(1):81-89.	"Ali MF, Soto A, Knoop FC, Conlon JM."	"Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae)."
DRAMP02222	GLLDTIKNTAKNLAVGLLDKIKCKMTGC	28	"Ranatuerin-2PLc (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana palustris (North America pickerel frog)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: May have antimicrobial activity against the Gram-negative bacterium E. coli.
Tissue specificity: Expressed by the skin glands."	Gram-negative bacterium: Escherichia coli (MIC=3 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11087945	Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.	"Basir YJ, Knoop FC, Dulka J, Conlon JM."	"Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris."
DRAMP02223	GIMDSVKNVAKNIAGQLLDKLKCKITGC	28	"Ranatuerin-2PLd (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana palustris (North America pickerel frog)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: May have antimicrobial activity against the Gram-negative bacterium E. coli.
Tissue specificity: Expressed by the skin glands."	Gram-negative bacterium: Escherichia coli (MIC=16 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11087945	Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.	"Basir YJ, Knoop FC, Dulka J, Conlon JM."	"Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris."
DRAMP02225	GIMDTVKNAAKDLAGQLDKLKCRITGC	27	"Ranatuerin-2PLf (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana palustris (North America pickerel frog)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: May have antimicrobial activity against the Gram-negative bacterium E. coli.
Tissue specificity: Expressed by the skin glands."	Gram-negative bacterium: Escherichia coli (MIC=23 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11087945	Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.	"Basir YJ, Knoop FC, Dulka J, Conlon JM."	"Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris."
DRAMP18494	FIHHIIGGLFSAGKAIHRLIRRRRR	25	TP4	L0CKG3	Piscidin	TP4	Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)	"Antibacterial, Antifungal, anticancer, wound healing, Anti-Gram+, Anti-Gram-, Antimicrobial"	Protein level	Alpha helix	"1.0x sarkosyl can drive TP4 into a conformational change from a non-structure to an alpha-helical structure, and that LPS can also drive TP4 to an alpha-helical structure but with high hydrophobicity and low solubility."	5H2S	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity. Has hemolytic activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=8 ¦Ìg/ml; MBC=16 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=16 ¦Ìg/ml; MBC=32 ¦Ìg/ml);##Gram-negative bacterium: Pseudomonas aeruginosa (MIC=64 ¦Ìg/ml; MBC=128 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)"	"[Ref.29040295] 2% hemolysis at 0.78 ¦Ìg/ml, 5% hemolysis at 1.56 ¦Ìg/ml, 45% hemolysis at 3.13 ¦Ìg/ml, 85% hemolysis at 6.25 ¦Ìg/ml, 98% hemolysis at 12.50 ¦Ìg/ml, 100% hemolysis at 25.00 ¦Ìg/ml against mouse red blood cell"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	"bacterial outer membrane target protein, OprI-binding"	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP03002	GIGAVLKVLTTGLPALISWIKRKRQQ	26	"Melittin (Allergen Api m 3; Allergen Api m III; Insects, animals)"	"P01501,P01503"	Belongs to the melittin family	MELT	Apis mellifera (Honeybee)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	"2MLT, 3QRX, 1BH1"	"Function: Main toxin of bee venom with strong hemolytic activity. Forms a pore in the cell membrane by inserting into lipid bilayers in an alpha-helical conformation and has multiple effects, probably, as a result of its interaction with negatively charged phospholipids. It inhibits well known transport pumps such as the Na+-K+-ATPase and the H+-K+-ATPase. It increases the permeability of cell membranes to ions, particularly Na+ and indirectly Ca2+, because of the Na+-Ca2+-exchange. It acts synergistically with phospholipase A2. "	"[Ref.29783753] Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=2 ¦ÌM), Listeria monocytogenes CMCC 54004 (MIC=1 ¦ÌM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=1 ¦ÌM), Escherichia coli UB 1005 (MIC=2 ¦ÌM), Salmonella pullorum C7913 (MIC=8 ¦ÌM), Salmonella enterica subsp enterica CMCC 50071 (MIC=2 ¦ÌM)"	[Ref.29859288] MHC=1 ¦ÌM against human red blood cell.##[Ref.2978375] 46.80% hemolysis at 2¦ÌM against human red blood cell##[Ref.20472009] Wild-type melittin:AVG ¡À S.D.(%)=0.077¡À0.002 (35) against human red blood cell.	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane (forms a transmembrane alpha-helix in the cell membrane.)	29859288##29783753##6309516##20472009##20403370##5300771	Gene. 2018 May 30. pii: S0378-1119(18)30617-6.##Molecules. 2018 May 19;23(5). pii: E1220. ##Eur J Biochem. 1983 Sep 1;135(1):123-126.##Peptides. 2010 Aug;31(8):1473-1479.##Toxicon. 2010 Sep 1;56(3):355-362.##Res Dev Tech Rep. 1967 Dec 5:1-13.	"Wanmakok M, Orrapin S, Intorasoot A, Intorasoot S.##Hou J, Liu Z, Cao S, Wang H, Jiang C, Hussain MA, Pang S.##Vlasak R, Unger-Ullmann C, Kreil G, Frischauf AM.##Sciani JM, Marques-Porto R, Louren?o Junior A, Orsi Rde O, Ferreira Junior RS, Barraviera B, Pimenta DC.##Ferreira Junior RS, Sciani JM, Marques-Porto R, Junior AL, Orsi Rde O, Barraviera B, Pimenta DC.##Fennell JF, Shipman WH, Cole LJ."	Expression in Escherichia coli of novel recombinant hybrid antimicrobial peptide AL32-P113 with enhanced antimicrobial activity in vitro.##Broad-Spectrum Antimicrobial Activity and Low Cytotoxicity against Human Cells of a Peptide Derived from Bovine AlphaS1-Casein.##Nucleotide sequence of cloned cDNA coding for honeybee prepromelittin.##Identification of a novel melittin isoform from Africanized Apis mellifera venom.##Africanized honey bee (Apis mellifera) venom profiling: Seasonal variation of
DRAMP02237	GLMDTIKGVAKTVAASWLDKLKCKITGC	28	"Ranatuerin-2Ya (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Not found	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Ranatuerin-2Ya showed appreciably greater cytolytic activity against HepG2 cells (LC(50)=20microM) than against erythrocytes (LC(50)>100microM).	[Ref.19254736] Gram-negative bacterium: Escherichia coli (MIC=50 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=50 ?M).	[Ref.19254736] LC50>100 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19254736	Toxicon. 2009 Jun;53(7-8):699-705. doi: 10.1016/j.toxicon.2009.02.018.	"Conlon JM, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis."
DRAMP02238	GLADYWRTAFRANFANLGPGIRCKSARC	28	"Ranatuerin-2ZHa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana zhenhaiensis (Chinese brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=1 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2 ?M), Pseudomonas aeruginosa ATCC 9027 (MIC=6 ?M).##Yeast: Candida albicans ATCC 2002 (MIC>32 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22943778	Zoolog Sci. 2012 Sep;29(9):553-558.	"Xu B, Che H, Kang L, Zheng S, Mu S, Wan F."	"Molecular Cloning and Functional Characterization of Novel Antimicrobial Peptides from the Skin of Brown Frog, Rana zhenhaiensis."
DRAMP02239	SMISVLKNLGKVGLGFVACKVNKQC	25	"Ranatuerin-1Ga (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana grylio (North American pig frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: Escherichia coli (MIC=3.5 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=60 ?M).##Yeast: Candida albicans (MIC=110 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10828493	Regul Pept. 2000 Jun 30;90(1-3):53-60.	"Kim JB, Halverson T, Basir YJ, Dulka J, Knoop FC, Abel PW, Conlon JM."	Purification and characterization of antimicrobial and vasorelaxant peptides from skin extracts and skin secretions of the North American pig frog Rana grylio.
DRAMP02241	GLLLDTLKGAAKDIAGIALEKLKCKITGCKP	31	"Ranatuerin-2G (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana grylio (North American pig frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: Escherichia coli (MIC=19 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=150 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10828493	Regul Pept. 2000 Jun 30;90(1-3):53-60.	"Kim JB, Halverson T, Basir YJ, Dulka J, Knoop FC, Abel PW, Conlon JM."	Purification and characterization of antimicrobial and vasorelaxant peptides from skin extracts and skin secretions of the North American pig frog Rana grylio.
DRAMP01390	TSRCYIGYRRKVVCS	15	"Odorranain-T1 (OdT1; Frogs, amphibians, animals)"	A6MBS1	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Odorranain-T1 adopts 28.2% turn structure in water solution.	None	Function: Odorranain-T1 exhibites moderate antimicrobial activities against all of the tested microbes.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=17.50 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=35.00 ¦Ìg/ml), Bacillus subtilis (MIC=17.50 ¦Ìg/ml).##Yeast: Candida albicans (MIC=8.75 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01389	FLPPSPWKETFRTS	14	"Odorranain-S1 (OdS1; Frogs, amphibians, animals)"	"A6MBS0, A6MBR9"	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	Function: Odorranain-S1 exhibites moderate antimicrobial activities against all of the tested microbes.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=42.50 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=21.25 ¦Ìg/ml), Bacillus subtilis (MIC=85.00 ¦Ìg/ml).##Yeast: Candida albicans (MIC=21.25 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP02252	GLLDAIKDTAQNLFANVLDKIKCKFTKC	28	"Ranatuerin 2SKa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana sakuraii (Japanese brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: Escherichia coli (MIC=50 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC>50 ?M).##Yeast: Candida albicans (MIC>50 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys23 and Cys28)	Disulfide bond between Cys23 and Cys28.	L	No cytotoxicity information found	Not found	17174009	Peptides. 2007 Mar;28(3):505-514.	"Suzuki H, Iwamuro S, Ohnuma A, Coquet L, Leprince J, Jouenne T, Vaudry H, Taylor CK, Abel PW, Conlon JM."	Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii.
DRAMP01108	GIGTKILGGVKTALKGALKELASTYVN	27	"Maximin-2 (Toads, amphibians, animals)"	"P83081, P83086, Q58T49"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Maximins are linear cationic peptides and easy to form membrane pore and they may induce a detergent-type disruption of sperm membrane like in the case of magainins.	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. Has little hemolytic activity. 
Tissue specificity: Expressed by the skin glands."	"[Ref.11835991] Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=19.5 ?g/ml), Klebsiella pneumoniae (MIC=9 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=19.5 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=19.5 ?g/ml), Bacillus megatherium (MIC=19.5 ?g/ml), Bacillus dysenteriae (MIC=2.7 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=3 ?g/ml)."	[Ref:11835991]Little hemolytic activity at 50 ¦Ìg/ml against red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-9.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP03998	RKKWFW	6	PAF26 (Trp-rich; combinatorial library)	No entry found 	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Synthetic	Rich	"In general, positively charged residues (arginine or lysine) and residues with aromatic rings (tryptophan or phenylalanine) rendered antifungal activity."	None	"Function: Antibacterial against Gram-negative bacterium. The antifungal mixture is also antibacterial, with a predominance of basic and aromatic residues."	"[Ref.11976121] Gram-negative bacterium: Escherichia coli DH5¦Á (MIC=160 ?M, IC50>80 ?M);##Fungi: Penicillium digitatum PHI-26 (MIC=20 ?M, IC50=11 ¡À 1 ?M), Penicillium italicum PHI-1 (MIC=40 ?M,  IC50=22 ¡À 3 ?M), Botrytis cinerea CECT2100 (MIC=60 ?M, IC50=38 ¡À 24 ?M), Fusarium oxysporum CECT2866 (MIC=80 ?M, IC50=45 ¡À 4 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11976121	Appl Environ Microbiol. 2002 May;68(5):2453-60.	"L¨®pez-Garc¨ªa B, P¨¦rez-Pay¨¢ E, Marcos JF."	Identification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library.
DRAMP01107	GIGTKILGGVKTALKGALKELASTYAN	27	"Maximin-1 (Toads, amphibians, animals)"	"P83080, Q58T87"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral, Anti-cancer"	Protein level	Not found	Maximins are linear cationic peptides and easy to form membrane pore and they may induce a detergent-type disruption of sperm membrane like in the case of magainins.	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. Has little hemolytic activity. Possess a significant cytotoxicity against tumor cell lines. Possess a significant anti-HIV activity. High spermicidal activity.
Toxic dose: LD50 is 8.2 mg/kg by intraperitoneal injection into mice.
Tissue specificity: Expressed by the skin glands."	"[Ref.11835991] Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=19.5 ?g/ml), Klebsiella pneumoniae (MIC=9 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=19.5 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=19.5 ?g/ml), Bacillus megatherium (MIC=19.5 ?g/ml), Bacillus dysenteriae (MIC=2.7 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=3 ?g/ml);##Virus: HIV-1 (IC50=15.5 ?g/ml, EC50=21.4 ?g/ml);##Cancer cell lines: C8166 (IC50=15.3 ?g/ml), Molt-4 (IC50=24.3 ?g/ml), BIU-87 (IC50=20.5 ?g/ml), T24 (IC50=35.4 ?g/ml)."	[Ref:11835991]Little hemolytic activity at 50 ¦Ìg/ml against red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-9.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP02268	GWASKIGQTLGKIAKVGLKELIQPK	25	"Xenopsin precursor fragment (XPF; Frogs, amphibians, animals)"	P07198	Belongs to the magainin family	Not found	Xenopus laevis (African clawed frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: XPF has antimicrobial activity.
Tissue specificity: XPF is synthesized in the stomach and stored in a novel granular multinucleated cell in the gastric mucosa, it is stored as active, processed peptides in large granules within the granular gland secretions of the skin."	"Gram-negative bacteria: Escherichia coli (MIC=16-31 ?g/ml), K. Pneumonae (MIC=62-125 ?g/ml), Pseudomonas aeruginosa (MIC=125-250 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=250-500 ?g/ml), Streptococcus faecalis (MIC=250-500 ?g/ml).##Yeast: Candida albicans (MIC=250-500 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1717472	J Biol Chem. 1991 Oct 15;266(29):19851-19857.	"Moore KS, Bevins CL, Brasseur MM, Tomassini N, Turner K, Eck H, Zasloff M."	Antimicrobial peptides in the stomach of Xenopus laevis.
DRAMP02269	GVLSNVIGYLKKLGTGALNAVLKQ	24	"Antimicrobial peptide PGQ (PGQ; Frogs, amphibians, animals)"	P39080	Belongs to the magainin family	pgq	Xenopus laevis (African clawed frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix(potential)	Not found	None	"Function: Antimicrobial peptide.
Tissue specificity: Is synthesized in the stomach and stored in a novel granular multinucleated cell in the gastric mucosa. It is stored as active, processed peptides in large granules within the granular gland secretions of the skin."	"Gram-negative bacteria: Escherichia coli (MIC=62-250 ?g/ml), K. Pneumonae (MIC=125-250 ?g/ml), Pseudomonas aeruginosa (MIC=250-500 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=250-500 ?g/ml), Streptococcus faecalis (MIC=250-500 ?g/ml).##Yeast: Candida albicans (MIC=250-500 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1717472	J Biol Chem. 1991 Oct 15;266(29):19851-19857.	"Moore KS, Bevins CL, Brasseur MM, Tomassini N, Turner K, Eck H, Zasloff M."	Antimicrobial peptides in the stomach of Xenopus laevis.
DRAMP02271	GIGKFLHSAKKFGKAFVGEIMNS	23	"Magainin-2 (Magainin II; chain of Magainins; Frogs, amphibians, animals)"	C0HKN6	Belongs to the gastrin/cholecystokinin family. Magainin subfamily.	N/A	Xenopus ruwenzoriensis (Uganda clawed frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal"	Protein level	Alpha helix	"The secondary structure is shown to be helical in dodecylphosphocholine micelles, sodium dodecylsulfate micelles, and trifluoroethanol/water solution."	"2MAG, 2LSA resolved by NMR."	"Function: Antimicrobial peptides that inhibit the growth of numerous species of bacteria and fungi and induce osmotic lysis of protozoa. Magainins are membrane lytic agents.
Tissue specificity: Synthesized in the stomach and stored in a novel granular multinucleated cell in the gastric mucosa. It is stored as active, processed peptides in large granules within the granular gland secretions of the skin."	"Gram-negative bacteria: Escherichia coli D31 (MIC=5 ?g/ml), Klebsiella pneumoniae (MIC=10 ?g/ml), Escherichia coli (MIC=50 ?g/ml), Pseudomonas putida (MIC=10 ?g/ml), Citrobacter freundii (MIC=30 ?g/ml), Enterobacter cloacae (MIC=50 ?g/ml), Pseudomonas aeruginosa (MIC=100 ?g/ml), Serratia marcescens (MIC=100 ?g/ml), Proteus mirabilis (MIC>100 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis (MIC=10 ?g/ml), Staphylococcus aureus (MIC=50 ?g/ml), Streptococcus fecalis (MIC>100 ?g/ml).##Protozoa: Paramecium caudatum (MIC=10 ?g/ml).##Yeast: Candida albicans (MIC=80 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	3299384##9090128##PubMed ID is not available	Proc Natl Acad Sci U S A. 1987 Aug;84(15):5449-5453.##J Biomol NMR. 1997 Feb;9(2):127-135.##To be Published.	"Zasloff M.##Gesell J, Zasloff M, Opella SJ.##Vermeer LS, Kozlowska J, Lorenz CD, Mason JA."	"Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.##Two-dimensional 1H NMR experiments show that the 23-residue magainin antibiotic peptide is an alpha-helix in dodecylphosphocholine micelles, sodium dodecylsulfate micelles, and trifluoroethanol/water solution.##All Atom Simulations of the Initial Binding of Magainin and Pleurocidin to Membranes Comprising a Mixture of Anionic and Zwitterionic"
DRAMP02272	GMASKAGAIAGKIAKVALKAL	21	"PGLa (chain of PYLa/PGLa A; Frogs, amphibians, animals)"	"Q99134, B7ZSG6, Q91826"	Belongs to the gastrin/cholecystokinin family (Magainin subfamily)	pgla-a AND pgla-b	Xenopus laevis (African clawed frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: PGLa display a broad-spectrum of antibacterial activity against a range of Gram-positive and Gram-negative bacteria. PGLa also displays antifungal activity against C. albicans ATCC 14053.
Tissue specificity: Expressed by the skin glands. Synthesized in the stomach and stored in a novel granular multinucleated cell in the gastric mucosa. Stored as active, processed peptides in large granules within the granular gland secretions of the skin.
PTM: Leucine amide at position 21."	"Gram-negative bacteria: Escherichia coli 25922 (MIC=62-125 ?g/ml), Klebsiella pneumoniae 13883 (MIC=250-500 ?g/ml), Pseudomonas aeruginosa 27853 (MIC=250-500 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus 29213 (MIC=125-500 ?g/ml), Strepococcus faecalis (MIC>500 ?g/ml).##Yeast: Candida albicans 14053 (MIC=250-500 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	3606567##1717472	Biochem J. 1987 Apr 1;243(1):113-120.##J Biol Chem. 1991 Oct 15;266(29):19851-19857.	"Giovannini MG, Poulter L, Gibson BW, Williams DH.##Moore KS, Bevins CL, Brasseur MM, Tomassini N, Turner K, Eck H, Zasloff M."	Biosynthesis and degradation of peptides derived from Xenopus laevis prohormones.##Antimicrobial peptides in the stomach of Xenopus laevis.
DRAMP02274	SAPRGCWTKSYPPKPCK	17	"Ranacyclin-E (Frogs, amphibians, animals)"	P83663	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana esculenta (Edible frog) (Pelophylax esculentus)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antibacterial activity. The mature peptide inserts into the hydrophobic core of the bacterial cell membrane and increases permeability without disrupting membrane integrity. Probably binds to the outer membrane surface before aggregating to form transmembrane pores. Has hemolytic activity. Probably binds to the outer membrane surface before aggregating to form transmembrane pores.
Tissue specificity: Expressed by the skin granular glands."	"[Ref.14636071]Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=3 ?M), Staphylococcus lentus (MIC=7 ?M), Micrococcus luteus (MIC=5 ?M);##Gram-negative bacteria: Yersinia pseudotuberculosis YP III (MIC=9 ?M), Pseudomonas syringae pv tabaci (MIC=80 ?M);##Fungi: Candida tropicalis (MIC=7.4 ?M), C. guillermondii (MIC=3.4 ?M), Phytophthora nicotianae spores (MIC=32 ?M)."	[Ref.14636071] It has 55% hemolytic activity at 100 ¦ÌM against human erythrocytes	Cyclic	Free	Amidation	Disulfide bond between Cys6 and Cys16.	L	No cytotoxicity information found	Cell membrane	14636071	Biochemistry. 2003 Dec 2;42(47):14023-14035.	"Mangoni ML, Papo N, Mignogna G, Andreu D, Shai Y, Barra D, Simmaco M."	"Ranacyclins, a new family of short cyclic antimicrobial peptides: biological function, mode of action, and parameters involved in target specificity."
DRAMP02275	GALRGCWTKSYPPKPCK	17	"Ranacyclin-T (Frogs, amphibians, animals)"	P83719	Belongs to the frog skin active peptide family (Brevinin subfamily)	RNCT	Rana temporaria (European common frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	MOA: The mature peptide inserts into the hydrophobic core of the bacterial cell membrane and increases permeability without disrupting membrane integrity. Probably binds to the outer membrane surface before aggregating to form transmembrane pores. Has hemolytic activity.	"[Ref.14636071]Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=3 ?M), Staphylococcus lentus (MIC=10 ?M), Micrococcus luteus (MIC=8 ?M);##Gram-negative bacteria: Escherichia coli D21 (MIC=30 ?M), Yersinia pseudotuberculosis YP III (MIC=5 ?M), Pseudomonas syringae pv tabaci (MIC=16 ?M);##Fungi: Candida albicans ATCC 10231 (MIC=22 ?M), Candida tropicalis (MIC=14 ?M), C. guillermondii (MIC=1 ?M), Phytophthora nicotianae spores (MIC=16 ?M)."	[Ref.14636071] It has 20% hemolytic activity at 100 ¦ÌM against human erythrocytes	Cyclic	Free	Amidation	Disulfide bond between Cys6 and Cys16.	L	No cytotoxicity information found	Cell membrane	14636071	Biochemistry. 2003 Dec 2;42(47):14023-14035.	"Mangoni ML, Papo N, Mignogna G, Andreu D, Shai Y, Barra D, Simmaco M."	"Ranacyclins, a new family of short cyclic antimicrobial peptides: biological function, mode of action, and parameters involved in target specificity."
DRAMP02276	AALKGCWTKSIPPKPCSGKR	20	"Ranacyclin B3 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana grahami (Ranidae frogs)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus (MIC=11.7 ?M).##Yeast: Candida albicans (MIC=23.4 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bond between Cys6 and Cys16.	L	No cytotoxicity information found	Not found	21927839	Amino Acids. 2012 Jul;43(1):309-316.	"Yan X, Liu H, Yang X, Che Q, Liu R, Yang H, Liu X, You D, Wang A, Li J, Lai R."	Bi-functional peptides with both trypsin-inhibitory and antimicrobial activities are frequent defensive molecules in Ranidae amphibian skins.
DRAMP02277	AALRGCWTKSIPPKPCSGKR	20	"Ranacyclin B5 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana grahami (Ranidae frogs)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus (MIC=5.8 ?M).##Yeast: Candida albicans (MIC=23.1 ?M)	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bond between Cys6 and Cys16.	L	No cytotoxicity information found	Not found	21927839	Amino Acids. 2012 Jul;43(1):309-316.	"Yan X, Liu H, Yang X, Che Q, Liu R, Yang H, Liu X, You D, Wang A, Li J, Lai R."	Bi-functional peptides with both trypsin-inhibitory and antimicrobial activities are frequent defensive molecules in Ranidae amphibian skins.
DRAMP02278	AALRGCWTKSIPPKPCPGKR	20	"Ranacyclin-B-RL1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana livida (Ranidae frogs)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus (MIC=5.8 ?M), Bacillus subtilis (MIC=46.2 ?M);##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bond between Cys6 and Cys16.	L	No cytotoxicity information found	Not found	21927839	Amino Acids. 2012 Jul;43(1):309-316.	"Yan X, Liu H, Yang X, Che Q, Liu R, Yang H, Liu X, You D, Wang A, Li J, Lai R."	Bi-functional peptides with both trypsin-inhibitory and antimicrobial activities are frequent defensive molecules in Ranidae amphibian skins.
DRAMP02281	SALVGCWTKSYPPNPCFGRG	20	"Ranacyclin-B-RN6 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Hylarana nigrovittata (Ranidae frogs)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus (MIC=11.7 ?M).##Yeast: Candida albicans (MIC=46.7 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bond between Cys6 and Cys16.	L	No cytotoxicity information found	Not found	21927839	Amino Acids. 2012 Jul;43(1):309-316.	"Yan X, Liu H, Yang X, Che Q, Liu R, Yang H, Liu X, You D, Wang A, Li J, Lai R."	Bi-functional peptides with both trypsin-inhibitory and antimicrobial activities are frequent defensive molecules in Ranidae amphibian skins.
DRAMP02288	FIGPVLKIAAGILPTAICKIFKKC	24	"Gaegurin-RN1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana nigrovittata 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has hemolytic activity against rabbit red cells..	"[Ref.19778602]Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=2.34 ?g/ml), Staphylococcus aureus ATCC43300 (MIC=9.38 ?g/ml), Bacillus subtilis (MIC=4.69 ?g/ml);##Gram-negative bacterium: Escherichia coli ML-35P (MIC=18.75 ?g/ml);##Yeast: Candida albicans ATCC2002 (MIC=4.69 ?g/ml)"	[Ref.19778602] It has 46.13 ¡À 1.49% hemolytic activity at 100 ¦Ìg/ml against rabbit red blood cells	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71.	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP02289	FVGPVLKIAAGILPTAICKIYKKC	24	"Gaegurin-RN4 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana nigrovittata 	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Function: Has hemolytic activity against rabbit red cells.	"[Ref.19778602]Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=1.17 ?g/ml), Staphylococcus aureus ATCC43300 (MIC=9.38 ?g/ml), Bacillus subtilis (MIC=2.34 ?g/ml);##Yeast: Candida albicans ATCC2002 (MIC=2.34 ?g/ml)."	[Ref.19778602] It has 18.64 ¡À 0.25% hemolytic activity at 100 ¦Ìg/ml against rabbit red blood cells	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71.	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP02290	FLGPIIKIATGILPTAICKFLKKC	24	"Gaegurin-RN5 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana nigrovittata 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Has hemolytic activity against rabbit red cells.	"[Ref.19778602]Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=3.75 ?g/ml), Staphylococcus aureus ATCC43300 (MIC=62.50 ?g/ml), Bacillus subtilis (MIC=4.69 ?g/ml);##Gram-negative bacterium: Escherichia coli ML-35P (MIC=37.50 ?g/ml);##Yeast: Candida albicans ATCC2002 (MIC=4.69 ?g/ml)."	[Ref.19778602] It has no detectable hemolysis at the concentration up to 100 ¦Ìg/ml	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	19778602	Genomics. 2010 Jan;95(1):66-71.	"Ma Y, Liu C, Liu X, Wu J, Yang H, Wang Y, Li J, Yu H, Lai R."	"Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata."
DRAMP02291	SLFSLIKAGAKFLGKNLLKQGACYAACKASKQC	33	"Gaegurin-1 (Gaegurin 1; GGN1; Frogs, amphibians, animals)"	P80395	Belongs to the frog skin active peptide family (Brevinin subfamily)	GGN1	Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has hemolytic activity against rabbit red cells.	"[Ref.7999137]Gram-positive bacteria: Micrococcus luteus (MIC=5 ?g/ml), Staphylococcus epidermidis (MIC=50 ?g/ml), Bacillus subtilis (MIC=50 ?g/ml);##Gram-negative bacteria: Klebsiella pneumoniae (MIC=100 ?g/ml), Shigella dysentariae (MIC=25 ?g/ml), Pseudomonas putida (MIC=50 ?g/ml), Pseudomonas aeruginosa (MIC=50 ?g/ml), Eshchericia coli (MIC=25 ?g/ml)."	"[Ref.7999137] It has 0.04% hemolytic activity at 0.1 ¦Ìg/ml, 0.14% hemolytic activity at 1 ¦Ìg/ml, 0.51% hemolytic activity at 10 ¦Ìg/ml, 0.59% hemolytic activity at 100 ¦Ìg/ml against human red blood cells."	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	7999137	Biochem Biophys Res Commun. 1994 Nov 30;205(1):948-954.	"Park JM, Jung J-E, Lee BJ.1994"	"Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."
DRAMP02292	GIMSIVKDVAKNAAKEAAKGALSTLSCKLAKTC	33	"Gaegurin-2 (Gaegurin 2; GGN2; Frogs, amphibians, animals)"	P80396	Belongs to the frog skin active peptide family (Brevinin subfamily)	GGN2	Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Micrococcus luteus (MIC=2.5 ?g/ml), Staphylococcus epidermidis (MIC=10 ?g/ml), Bacillus subtilis (MIC=10 ?g/ml);##Gram-negative bacteria: Klebsiella pneumoniae (MIC=25 ?g/ml), Shigella dysentariae (MIC=25 ?g/ml), Pseudomonas putida (MIC=50 ?g/ml), Pseudomonas aeruginosa (MIC=50 ?g/ml), Eshchericia coli (MIC=75 ?g/ml).##Fungi: Saccharomyces cerevisiae (MIC=150 ?g/ml), Candida albicans (MIC=150 ?g/ml), Salmonella typhimurium (MIC=150 ?g/ml), Proteus mirabilis (MIC>200 ?g/ml), Serratia marcescens (MIC>200 ?g/ml)."	"[Ref.7999137] It has 0.19% hemolytic activity at 0.1 ¦Ìg/ml, 0.16% hemolytic activity at 1 ¦Ìg/ml, 0.31% hemolytic activity at 10 ¦Ìg/ml, 0.82% hemolytic activity at 100 ¦Ìg/ml against human red blood cells."	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	7999137	Biochem Biophys Res Commun. 1994 Nov 30;205(1):948-954.	"Park JM, Jung JE, Lee BJ."	"Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."
DRAMP02293	GIMSIVKDVAKTAAKEAAKGALSTLSCKLAKTC	33	"Gaegurin-3 (Gaegurin 3; GGN3; Frogs, amphibians, animals)"	P80397	Belongs to the frog skin active peptide family (Brevinin subfamily)	GGN3	Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Micrococcus luteus (MIC=2.5 ?g/ml), Staphylococcus epidermidis (MIC=10 ?g/ml), Bacillus subtilis (MIC=10 ?g/ml);##Gram-negative bacteria: Klebsiella pneumoniae (MIC=25 ?g/ml), Shigella dysentariae (MIC=25 ?g/ml), Pseudomonas putida (MIC=50 ?g/ml), Pseudomonas aeruginosa (MIC=50 ?g/ml), Eshchericia coli (MIC=75 ?g/ml).##Fungi: Saccharomyces cerevisiae (MIC>200 ?g/ml), Candida albicans (MIC>200 ?g/ml), Salmonella typhimurium (MIC=150 ?g/ml), Proteus mirabilis (MIC>200 ?g/ml), Serratia marcescens (MIC>200 ?g/ml)."	"[Ref.7999137] It has 0.11% hemolytic activity at 0.1 ¦Ìg/ml, 0.12% hemolytic activity at 1 ¦Ìg/ml, 0.35% hemolytic activity at 10 ¦Ìg/ml, 1.20% hemolytic activity at 100 ¦Ìg/ml against human red blood cells."	Cyclic	Free	Cyclization (Cys27 and Cys33)	Disulfide bond between Cys27 and Cys33.	L	No cytotoxicity information found	Not found	7999137	Biochem Biophys Res Commun. 1994 Nov 30;205(1):948-954.	"Park JM, Jung JE, Lee BJ."	"Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."
DRAMP02294	GILDTLKQFAKGVGKDLVKGAAQGVLSTVSCKLAKTC	37	"Gaegurin-4 (Gaegurin 4; GGN4; Frogs, amphibians, animals)"	"P80398, Q91328, Q98TA6"	Belongs to the frog skin active peptide family (Brevinin subfamily)	GGN4	Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal"	Protein level	Alpha helix (3 helices; 22 residues)	"In 100% H2O, Gaegurin 4 contains a nascent turn near its C-terminal Rana box. Under a more hydrophobic condition it forms two amphipathic helices, one long encompassing residues 2-23 and the other consisting of residues 25-34 (Ref.2)."	2G9L resolved by NMR.	"Function: Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa. Has hemolytic activity against rabbit red cells.
Tissue specificity: Expressed by the skin glands.
PTM: Contains one disulfide bond 31-37."	"[Ref.7999137]Gram-positive bacteria: Micrococcus luteus (MIC=2.5 ?g/ml), Staphylococcus epidermidis (MIC=10 ?g/ml), Bacillus subtilis (MIC=10 ?g/ml);##Gram-negative bacteria: Klebsiella pneumoniae (MIC=25 ?g/ml), Shigella dysentariae (MIC=25 ?g/ml), Pseudomonas putida (MIC=100 ?g/ml), Pseudomonas aeruginosa (MIC=100 ?g/ml), Eshchericia coli (MIC=75 ?g/ml);##Fungi: Saccharomyces cerevisiae (MIC=200 ?g/ml), Candida albicans (MIC=200 ?g/ml), Salmonella typhimurium (MIC=200 ?g/ml), Proteus mirabilis (MIC>200 ?g/ml), Serratia marcescens (MIC>200 ?g/ml)."	"[Ref.7999137] It has 0.50% hemolytic activity at 0.1 ¦Ìg/ml, 0.74% hemolytic activity at 1 ¦Ìg/ml, 0.78% hemolytic activity at 10 ¦Ìg/ml, 1.67% hemolytic activity at 100 ¦Ìg/ml against human red blood cells"	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	No cytotoxicity information found	Not found	7999137##17141187##11004488	Biochem Biophys Res Commun. 1994 Nov 30;205(1):948-954.##Biochem Biophys Res Commun. 2007 Jan 19;352(3):592-597.##Biochim Biophys Acta. 2000 Jun 21;1492(1):185-190.	"Park JM, Jung JE, Lee BJ.##Chi SW, Kim JS, Kim DH, Lee SH, Park YH, Han KH.##Kwon SY, Carlson BA, Park JM, Lee BJ."	"Antimicrobial peptides from the skin of a Korean frog, Rana rugosa.##Solution structure and membrane interaction mode of an antimicrobial peptide gaegurin 4.##Structural organization and expression of the gaegurin 4 gene of Rana rugosa."
DRAMP02295	FLGALFKVASKVLPSVFCAITKKC	24	"Gaegurin-5 (Gaegurin 5; GGN5; Brevinin-1EMa; Frogs, amphibians, animals)"	"P80399, Q91329"	Belongs to the frog skin active peptide family (Brevinin subfamily)	GGN5	Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal"	Protein level	Not found	Not found	None	"Function: Has low hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa. PTM: Problely contains one disulfide bond 18-24."	"[Ref.7999137]Gram-positive bacteria: Micrococcus luteus (MIC=2.5 ?g/ml), Staphylococcus epidermidis (MIC=10 ?g/ml), Bacillus subtilis (MIC=10 ?g/ml);##Gram-negative bacteria: Klebsiella pneumoniae (MIC=50 ?g/ml), Shigella dysentariae (MIC=50 ?g/ml), Pseudomonas putida (MIC=50 ?g/ml), Pseudomonas aeruginosa (MIC=100 ?g/ml), Eshchericia coli (MIC=50 ?g/ml);##Fungi: Saccharomyces cerevisiae (MIC=50 ?g/ml), Candida albicans (MIC=50 ?g/ml), Salmonella typhimurium (MIC=200 ?g/ml), Proteus mirabilis (MIC>200 ?g/ml)."	"[Ref.7999137] It has 0.19% hemolytic activity at 0.1 ¦Ìg/ml, 0.31% hemolytic activity at 1 ¦Ìg/ml, 0.78% hemolytic activity at 10 ¦Ìg/ml, 1.01% hemolytic activity at 100 ¦Ìg/ml against human red blood cells"	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	7999137	Biochem Biophys Res Commun. 1994 Nov 30;205(1):948-954.	"Park JM, Jung JE, Lee BJ."	"Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."
DRAMP02296	FLPLLAGLAANFLPTIICKISYKC	24	"Gaegurin-6 (Gaegurin 6; GGN6; Frogs, amphibians, animals)"	P80400	Belongs to the frog skin active peptide family (Brevinin subfamily)	GGN6	Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has low hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa. PTM: Problely contains one disulfide bond 18-24."	"[Ref.7999137]Gram-positive bacteria: Micrococcus luteus (MIC=2.5 ?g/ml), Staphylococcus epidermidis (MIC=10 ?g/ml), Bacillus subtilis (MIC=10 ?g/ml);##Gram-negative bacteria: Klebsiella pneumoniae (MIC=50 ?g/ml), Shigella dysentariae (MIC=50 ?g/ml), Pseudomonas putida (MIC=50 ?g/ml), Pseudomonas aeruginosa (MIC=100 ?g/ml), Eshchericia coli (MIC=50 ?g/ml);##Fungi: Saccharomyces cerevisiae (MIC=50 ?g/ml), Candida albicans (MIC=50 ?g/ml), Salmonella typhimurium (MIC=200 ?g/ml), Proteus mirabilis (MIC>200 ?g/ml), Serratia marcescens (MIC>200 ?g/ml)."	"[Ref.7999137] It has 0.39% hemolytic activity at 0.1 ¦Ìg/ml, 0.62% hemolytic activity at 1 ¦Ìg/ml, 0.78% hemolytic activity at 10 ¦Ìg/ml, 0.86% hemolytic activity at 100 ¦Ìg/ml against human red blood cells"	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	7999137	Biochem Biophys Res Commun. 1994 Nov 30;205(1):948-954.	"Park JM, Jung JE, Lee BJ."	"Antimicrobial peptides from the skin of a Korean frog, Rana rugosa."
DRAMP02314	RCRFCCRCCPRMRGCGICCRF	21	"Hepcidin (fish, chordates, animals)"	A1Z0M0	Belongs to the hepcidin family	hamp	Larimichthys crocea (Croceine croaker) (Pseudosciaena crocea)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages.
Tissue specificity: Expressed in all tissues tested, with highest levels of expression in kidney and lowest levels in liver. Intra-peritoneal injection of lipopolysaccharide results in increased expression in heart, spleen and stomach, but not in kidney or liver.
PTM: Contains four disulfide bonds 2-19; 5-8; 6-15; 9-18."	"Gram-negative bacteria: Vibrio alginolyticus(MIC=24 ?M), V. fluvialis, V. harveyis (MIC=12 ?M) and Vibrio parahaemolyticus (MIC=6 ?M), Aeromonas hydrophila (MIC=6 ?M), Escherichia coli (MIC=24 ?M), Escherichia coli BL21(DE3)plysS (MIC=6 ?M);##Gram-positive bacteria: Bacillus cereus (MIC=24 ?M), Bacillus subtilis (MIC=6 ?M), C. glutamicum (MIC=3 ?M), Micrococcus luteus (MIC=3 ?M), M. lysodeikticus, Staphylococcus aureus (MIC=6 ?M) and S.epidermis (MIC=12 ?M).##Fungi: Aspergillus niger (MIC=24 ?M), F;##Graminearum (MIC=24 ?M) and Fusarium solani (MIC=24 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys2 and Cys19; Cys5 and Cys8; Cys6 and Cys15,Cys9 and Cys18."	L	No cytotoxicity information found	Not found	19150638##19344770	Peptides. 2009 Apr;30(4):638-646.##Fish Shellfish Immunol. 2009 Jun;26(6):864-870.	"Wang KJ, Cai JJ, Cai L, Qu HD, Yang M, Zhang M.##Zhang J, Yan Q, Ji R, Zou W, Guo G."	"Cloning and expression of a hepcidin gene from a marine fish (Pseudosciaena crocea) and the antimicrobial activity of its synthetic peptide.##Isolation and characterization of a hepcidin peptide from the head kidney of large yellow croaker, Pseudosciaena crocea."
DRAMP02330	FFHHIFRGIVHVGKTIHRLVTG	22	"Piscidin-1 (Pis-1; Piscidin 1; fish, chordates, animals)"	Q8UUG0	Belongs to the pleurocidin family	Not found	Morone saxatilis (Striped bass)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	"2JOS, 2OJM resolved by NMR."	Function: Exhibits broad spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria. Also has hemolytic activity. Seems to disrupt the membranes by adopting an alpha helical conformation and forming toroidal pores.	"[Ref.11713517]Gram-positive bacteria: Enterococcus faecalis VRE (MIC=5-10 ?M), E. faecalis (MIC=2.5-5 ?M), Listeria monocytogenes (MIC=2.5-5 ?M), Micrococcus luteus (MIC=10-20 ?M), Staphylococcus aureus MRSA (MIC=1.25-2.5 ?M), S. epidermitis (MIC=5-10 ?M), S. saprophiticus (MIC=5-10 ?M), Staphylococcus xylosus (MIC>20 ?M), S. agalactiae (MIC=1.25-2.5 ?M), S. bovis (MIC=1.25-2.5 ?M), S. equisimilis (MIC=2.5-5 ?M), S. mitis (MIC=1.25-2.5 ?M), S. Pneumonae (MIC=1.25-2.5 ?M), S. pyrogenes (MIC=1.25-2.5 ?M), Streptococcus iniae KST740 ak (MIC=1.25-2.5 ?M), S. iniae KSTSi 6P (MIC=1.25-2.5 ?M);##Gram-negative bacteria: Aeromonas hydrophila (MIC>20 ?M), Burkholderia cepacia (MIC>20 ?M), Vibrio Cholera (MIC=2.5-5 ?M), Escherichia coli (MIC=5-10 ?M), Enterobacter cloacae (MIC=10-20 ?M), E. Aerogenes (MIC=10-20 ?M), Klebsiella pneumoniae (MIC=2.5-5 ?M), K. oxytoca (MIC=5-10 ?M), Salmonella choleraesuis (MIC=10-20 ?M), S. typhimurium (MIC=10-20 ?M), S. arizonae (MIC=10-20 ?M), Serratia marcescens (MIC>20 ?M), Shigella flexneri (MIC=2.5-5 ?M), S. sonnei (MIC=5-10 ?M), Yersinia enterocolitica (MIC=2.5-5 ?M); Fungi: Neurospora crassa (MIC=1.56-3.12 ?M), A. fumigatus (MIC=50-100 ?M), F. axysporum (MIC=0.78-1.56 ?M), F. culmorum (MIC=0.39-0.78 ?M), C. ablicans (MIC=10-20 ?M), C. glabrata (MIC=10-20 ?M), C. lusitania (MIC=10-20 ?M), C. tropacalis (MIC=10-20 ?M)."	"[Ref.11713517]10% hemolytic activity at 5 ¦Ìg/mL, 60% hemolytic activity at 10 ¦Ìg/mL, 100% hemolytic activity at 50 ¦Ìg/mL against human erythrocytes "	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	11713517	Nature. 2001 Nov 15;414(6861):268-269.	"Silphaduang U, Noga EJ."	Peptide antibiotics in mast cells of fish.
DRAMP02331	FFHHIFRGIVHVGKTIHKLVTG	22	"Piscidin-2 (Pis-2; fish, chordates, animals)"	Q8UUG2	Belongs to the pleurocidin family	Not found	Morone chrysops (White bass)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Exhibits broad spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria as well as against a variety of fungi. Seems to disrupt the membranes by adopting an alpha helical conformation.
Tissue specificity: Expressed in gill, skin, intestine, spleen, anterior kidney, and blood cells."	"Gram-positive bacteria: Enterococcus faecalis (MIC=5-10 ?M), E. faecalis (MIC=2.5-5 ?M), Listeria monocytogenes (MIC=2.5-5 ?M), Micrococcus luteus (MIC=10-20 ?M), Staphylococcus aureus (MIC=1.25-2.5 ?M), S. epidermidis (MIC=5-10 ?M), S. saprophiticus (MIC=5-10 ?M), S. xylosus (MIC>20 ?M), Streptococcus agalactiae (MIC=1.25-2.5 ?M), S. bovis (MIC=1.25-2.5 ?M), S. equisimilis (MIC=2.5-5 ?M), S. mitis (MIC=1.25-2.5 ?M), Streptococcus pneumoniae (MIC=1.25-2.5 ?M), Streptococcus pyogenes (MIC=1.25-2.5 ?M), S. iniae KST740ak (MIC=1.25-2.5 ?M), S. iniae KSTSi 6P (MIC=1.25-2.5 ?M);##Gram-negative bacteria: Aeromonas hydrophila (MIC>20 ?M), Burkholderia cepacia (MIC>20 ?M), Vibrio cholera (MIC=2.5-5 ?M), Escherichia coli (MIC=5-10 ?M), Moraxella catarrhalis (MIC=2.5-5 ?M), Neisseria gonorrhoeae (MIC>20 ?M), Pseudomonas aeruginosa (MIC=5-10 ?M), Enterobacter cloacae (MIC=10-20 ?M), E. aerogenes (MIC=10-20 ?M), Klebsiella pneumoniae (MIC=2.5-5 ?M), K. oxytoca (MIC=5-10 ?M), Salmonella choleraesuis (MIC=10-20 ?M), Salmonella typhimurium (MIC=10-20 ?M), S. arizonae (MIC=10-20 ?M), Serratia marcescens (MIC>20 ?M), Shigella flexneri (MIC=2.5-5 ?M), S. sonnei (MIC=5-10 ?M), Yersinia enterocolitica (MIC=2.5-5 ?M).##Fungi: Neurospora crassa (MIC=1.56-3.12 ?M), Aspergillus fumigatus (MIC=50-100 ?M), Fusarium oxysporum (MIC=0.78-1.56 ?M), F. culmorum (MIC=0.39-0.78 ?M), Candida albicans (MIC=10-20 ?M), C. glabrata (MIC=10-20 ?M), C. lusitania (MIC=10-20 ?M), C. tropicalis (MIC=10-20 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	11739390	J Biol Chem. 2002 Feb 15;277(7):5030-5039.	"Lauth X, Shike H, Burns JC, Westerman ME, Ostland VE, Carlberg JM, Van Olst JC, Nizet V, Taylor SW, Shimizu C, Bulet P."	"Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass."
DRAMP02347	GKGRWLERIGKAGGIIIGGALDHL	24	"NRC-1 (fish, chordates, animals)"	No entry found	Not found	Not found	Pseudopleuronectes americanus (Winter flounder 1)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"C-terminal NH2, this NRC seris of peptides was identified by gene analysis and biological activity verified using synthetic peptides. "	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=64 ?g/ml), Aeromonas salmonicida 97-4 (MIC=64 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=16 ?g/ml), Salmonella enterica serovar Typhimurium 14028s (MIC>64 ?g/ml), Pseudomonas aeruginosa K799 (MIC>64 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=32 ?g/ml), Escherichia coli CGSC 4908 (MIC=32 ?g/ml), Escherichia coli UB1005 (MIC=32 ?g/ml), Escherichia coli DC2 (MIC=32 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC>64 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC>64 ?g/ml).##Yeast: Candida albicans C627 (MIC=64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02348	WLRRIGKGVKIIGGAALDHL	20	"NRC-2 (fish, chordates, animals)"	No entry found	Not found	Not found	Pseudopleuronectes americanus (Winter flounder 1a)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC>128 ?g/ml), Aeromonas salmonicida 97-4 (MIC=128 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=64 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC>64 ?g/ml), Pseudomonas aeruginosa K799 (MIC=64 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=32 ?g/ml), Escherichia coli CGSC 4908 (MIC=64 ?g/ml), E. coli UB1005 (MIC=64 ?g/ml), E. coli DC2 (MIC=64 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC>64 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC>64 ?g/ml).##Yeast: Candida albicans C627 (MIC>64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02349	GRRKRKWLRRIGKGVKIIGGAALDHL	26	"NRC-3 (fish, chordates, animals)"	No entry found	Not found	Not found	Pseudopleuronectes americanus (Winter flounder 1a-1)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=2 ?g/ml), Aeromonas salmonicida 97-4 (MIC=4 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=2 ?g/ml), Salmonella enterica serovar Typhimurium 14028s (MIC=8 ?g/ml), Pseudomonas aeruginosa K799 (MIC=2 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=1 ?g/ml), Escherichia coli CGSC 4908 (MIC=2 ?g/ml), Escherichia coli UB1005 (MIC=8 ?g/ml), Escherichia coli DC2 (MIC=2 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=8 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=8 ?g/ml).##Yeast: Candida albicans C627 (MIC=4 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02350	GWGSFFKKAAHVGKHVGKAALTHYL	25	"Pleurocidin (NRC-4; fish, chordates, animals)"	"P81941, P81619, Q9PRJ9, Q90ZY0, Q90VW6"	Belongs to the pleurocidin family	ple1 AND ple2	Pseudopleuronectes americanus (Winter flounder 2-2.1)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix (1 helices; 19 residues)	"From NMR structural studies with the uniformly (15)N-labeled peptide, a structure of pleurocidin is determined to be in a random coil conformation in aqueous solution whereas it assumes an alpha-helical structure in TFE and in dodecylphosphocholine (DPC) micelles.(Ref.2)"	1Z64?resolved by NMR.	May play a role in innate host defense.	"Gram-negative bacteria: Escherichia coli (MIC=2.2-3.3 ?M), Leucothrix mucor (MIC>35.0 ?M), Serratia marcescens (MIC>35.0 ?M), Pseudomonas aeruginosa (MIC>35.0 ?M), Aeromonas salmonicida (MIC=17.7-35.0 ?M), Cytophaga aquatilis (MIC=2.2-4.4 ?M), Pasteurella haemolytica (MIC=4.4-8.8 ?M), Salmonella typhimurium I (MIC=8.8-17.7 ?M), Salmonella typhimurium II (MIC=8.8-17.7 ?M);##Gram-positive bacteria: Bacillus subtilis (MIC=1.1-2.2 ?M), Staphylococcus aureus (MIC=17.7-35.0 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9115266	J Biol Chem. 1997 May 2;272(18):12008-12013.	"Cole A.M, Weis P, Diamond G."	"Isolation and characterization of pleurocidin, an antimicrobial peptide in the skin secretions of winter flounder."
DRAMP02351	FFRLLFHGVHHVGKIKPRA	19	"NRC-10 (fish, chordates, animals)"	No entry found	Not found	Not found	Pseudopleuronectes americanus (Winter flounder Z)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC>64 ?g/ml), Aeromonas salmonicida 97-4 (MIC=32 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=16 ?g/ml), Salmonella enterica serovar Typhimurium 14028s (MIC>64 ?g/ml), Pseudomonas aeruginosa K799 (MIC=32 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=8 ?g/ml), Escherichia coli CGSC 4908 (MIC=32 ?g/ml), Escherichia coli UB1005 (MIC=32 ?g/ml), Escherichia coli DC2 (MIC=32 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=32 ?g/ml), Staphylococcus aureus C623 (MRSA) (MIC=64 ?g/ml).##Yeast: Candida albicans C627 (MIC>64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02352	GWKKWLRKGAKHLGQAAIK	19	"NRC-16 (fish, chordates, animals)"	No entry found	Not found	Not found	Glyptocephalus cynoglossus (Witch flounder GC3.8-t)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=2 ?g/ml), A. salmonicida 97-4 (MIC=1 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=0.5 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC=16 ?g/ml), Pseudomonas aeruginosa K799 (MIC=4 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=1 ?g/ml), Escherichia coli CGSC 4908 (MIC=1 ?g/ml), E. coli UB1005 (MIC=2 ?g/ml), E. coli DC2 (MIC=0.5 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=16 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=32 ?g/ml).##Yeast: Candida albicans C627 (MIC=8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02357	FLGALIKGAIHGGRFIHGMIQNHH	24	"Pleurocidin-like peptide WF3 (NRC-5; fish, chordates, animals)"	Q90VW7	Belongs to the pleurocidin family	ple3	Pseudopleuronectes americanus (Winter flounder 3)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC>64 ?g/ml), A. salmonicida 97-4 (MIC>64 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=64 ?g/ml), Salmonella enterica serovar Typhimurium 14028s (MIC>64 ?g/ml), Pseudomonas aeruginosa K799 (MIC>64 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=32 ?g/ml), Escherichia coli CGSC 4908 (MIC=64 ?g/ml), Escherichia coli UB1005 (MIC=64 ?g/ml), Escherichia coli DC2 (MIC>64 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=32 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=32 ?g/ml).##Yeast: Candida albicans C627 (MIC>64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506##11113283	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.##Dev Comp Immunol. 2001 Mar;25(2):137-147.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE.##Douglas SE, Gallant JW, Gong Z, Hew C."	"Novel antimicrobial peptides derived from flatfish genes.##Cloning and developmental expression of a family of pleurocidin-like antimicrobial peptides from winter flounder, Pleuronectes americanus (Walbaum)."
DRAMP02358	GWGSIFKHGRHAAKHIGHAAVNHYL	25	"Pleurocidin-like peptide WF4 (NRC-6; fish, chordates, animals)"	"Q90ZX8, Q90ZX9"	Belongs to the pleurocidin family	ple4	Pseudopleuronectes americanus (Winter flounder 4-1.1)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=4 ?g/ml), A. salmonicida 97-4 (MIC=4 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=4 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC=64 ?g/ml), Pseudomonas aeruginosa K799 (MIC=16 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=4 ?g/ml), Escherichia coli CGSC 4908 (MIC=4 ?g/ml), E. coli UB1005 (MIC=4 ?g/ml), E. coli DC2 (MIC=2 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC>64 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=32 ?g/ml).##Yeast: Candida albicans C627 (MIC=32 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506##11113283	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.##Dev Comp Immunol. 2001 Mar;25(2):137-147.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE.##Douglas SE, Gallant JW, Gong Z, Hew C."	"Novel antimicrobial peptides derived from flatfish genes.##Cloning and developmental expression of a family of pleurocidin-like antimicrobial peptides from winter flounder, Pleuronectes americanus (Walbaum)."
DRAMP02359	RWGKWFKKATHVGKHVGKAALTAYL	25	"Pleurocidin-like peptide YT2 (NRC-7; fish, chordates, animals; Predicted)"	Q7SZH1	Not found	ple	Limanda ferruginea (Yellowtail flounder YT2)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=4 ?g/ml), A. salmonicida 97-4 (MIC=2 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=2 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC=8 ?g/ml), Pseudomonas aeruginosa K799 (MIC=4 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=2 ?g/ml), Escherichia coli CGSC 4908 (MIC=4 ?g/ml), E. coli UB1005 (MIC=4 ?g/ml), E. coli DC2 (MIC=4 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=64 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=64 ?g/ml).##Yeast: Candida albicans C627 (MIC=16 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02360	GWKSVFRKAKKVGKTVGGLALDHYLG	26	"Pleurocidin-like peptide AP1 (NRC-11; fish, chordates, animals; Predicted)"	Q7SZH4	Not found	ple	Hippoglossoides platessoides (American plaice AP1)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=8 ?g/ml), A. salmonicida 97-4 (MIC=8 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=4 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC=32 ?g/ml), Pseudomonas aeruginosa K799 (MIC=32 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=4 ?g/ml), Escherichia coli CGSC 4908 (MIC=4 ?g/ml), E. coli UB1005 (MIC=16?g/ml), E. coli DC2 (MIC=4 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=64 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC>64 ?g/ml).##Yeast: Candida albicans C627 (MIC=32 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02361	GWKKWFNRAKKVGKTVGGLAVDHYLG	26	"Pleurocidin-like peptide AP2 (NRC-12; fish, chordates, animals; Predicted)"	Q7SZH3	Not found	ple	Hippoglossoides platessoides (American plaice AP2)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=2 ?g/ml), A. salmonicida 97-4 (MIC=2 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=2 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC=8?g/ml), Pseudomonas aeruginosa K799 (MIC=4 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=1 ?g/ml), Escherichia coli CGSC 4908 (MIC=2 ?g/ml), E. coli UB1005 (MIC=8 ?g/ml), E. coli DC2 (MIC=2 ?g/ml);##Gram-positive bacteria: S. epidermidis C621 (MIC=8 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=16 ?g/ml).##Yeast: Candida albicans C627 (MIC=4 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02362	GWRTLLKKAEVKTVGKLALKHYL	23	"Pleurocidin-like peptide AP3 (NRC-13; fish, chordates, animals; Predicted)"	Q7SZH2	Not found	ple	Hippoglossoides platessoides (American plaice AP3)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=4 ?g/ml), A. salmonicida 97-4 (MIC=2 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=2 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC=8 ?g/ml), Pseudomonas aeruginosa K799 (MIC=4 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=1 ?g/ml), Escherichia coli CGSC 4908 (MIC=2 ?g/ml), E. coli UB1005 (MIC=4 ?g/ml), E. coli DC2 (MIC=2 ?g/ml).##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=4 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=4 ?g/ml).##Yeast: Candida albicans C627 (MIC=4 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02363	AGWGSIFKHIFKAGKFIHGAIQAHND	26	"Pleurocidin-like peptide GcSc4C5 (NRC-14; fish, chordates, animals)"	Q7SZH0 	Not found	ple	Glyptocephalus cynoglossus (Witch flounder GcSc4C5)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=32 ?g/ml), A. salmonicida 97-4 (MIC=16 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=16 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC>64 ?g/ml), Pseudomonas aeruginosa K799 (MIC=32 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=8 ?g/ml), Escherichia coli CGSC 4908 (MIC=16 ?g/ml), E. coli UB1005 (MIC=16 ?g/ml), E. coli DC2 (MIC=16 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=16 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=16 ?g/ml).##Yeast: Candida albicans C627 (MIC>64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02364	GFWGKLFKLGLHGIGLLHLHL	21	"Pleurocidin-like peptide GcSc4B7 (NRC-15; fish, chordates, animals; Predicted)"	Q7SZG9	Not found	ple	Glyptocephalus cynoglossus (Witch flounder GcSc4B7)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=8 ?g/ml), A. salmonicida 97-4 (MIC=16 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=4 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC=16 ?g/ml), Pseudomonas aeruginosa K799 (MIC=8 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=4 ?g/ml), Escherichia coli CGSC 4908 (MIC=8 ?g/ml), E. coli UB1005 (MIC=8 ?g/ml), E. coli DC2 (MIC=8 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=4 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=4 ?g/ml).##Yeast: Candida albicans C627 (MIC=16 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02365	GWKKWLRKGAKHLGQAAIKGLAS	23	"Pleurocidin-like peptide GC3.8 (NRC-17; fish, chordates, animals; Predicted)"	Q7SZG8	Not found	ple	Glyptocephalus cynoglossus (Witch flounder GC3.8)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=2 ?g/ml), A. salmonicida 97-4 (MIC=1 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=1 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC=8 ?g/ml), Pseudomonas aeruginosa K799 (MIC=4 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=2 ?g/ml), Escherichia coli CGSC 4908 (MIC=1 ?g/ml), E. coli UB1005 (MIC=4 ?g/ml), E. coli DC2 (MIC=1 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=32 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=16 ?g/ml).##Yeast: Candida albicans C627 (MIC=8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02366	GWKKWFTKGERLSQRHFA	18	"Pleurocidin-like peptide GC3.2 (NRC-18; fish, chordates, animals; Predicted)"	Q7SZG7	Not found	ple	Glyptocephalus cynoglossus (Witch flounder GC3.2)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC>64 ?g/ml), A. salmonicida 97-4 (MIC=128 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=32 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC>64 ?g/ml), Pseudomonas aeruginosa K799 (MIC>64 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=64 ?g/ml), Escherichia coli CGSC 4908 (MIC=64 ?g/ml), E. coli UB1005 (MIC=64 ?g/ml), E. coli DC2 (MIC=64 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC>64 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC>64 ?g/ml).##Yeast: Candida albicans C627 (MIC>64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02367	FLGLLFHGVHHVGKWIHGLIHGHH	24	"Pleurocidin-like peptide Hb26 (NRC-19; fish, chordates, animals; Predicted)"	Q7SZG6	Not found	ple	Hippoglossus hippoglossus (Halibut Hb26)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=64 ?g/ml), A. salmonicida 97-4 (MIC>64 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=16 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC=64 ?g/ml), Pseudomonas aeruginosa K799 (MIC=32 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=8 ?g/ml), Escherichia coli CGSC 4908 (MIC=32 ?g/ml), E. coli UB1005 (MIC=16 ?g/ml), E. coli DC2 (MIC=32 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=8 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC=8 ?g/ml).##Yeast: Candida albicans C627 (MIC=64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02368	GFLGILFHGVHHGRKKALHMNSERRS	26	"Pleurocidin-like peptide Hb18 (NRC-20; fish, chordates, animals; Predicted)"	Q7SZG5	Not found	ple	Hippoglossus hippoglossus (Halibut Hb18)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC>64 ?g/ml), A. salmonicida 97-4 (MIC>64 ?g/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC>64 ?g/ml), S. enterica serovar Typhimurium 14028s (MIC>64 ?g/ml), Pseudomonas aeruginosa K799 (MIC>64 ?g/ml), Pseudomonas aeruginosa Z61 (MIC=64 ?g/ml), Escherichia coli CGSC 4908 (MIC>64 ?g/ml), E. coli UB1005 (MIC>64 ?g/ml), E. coli DC2 (MIC>64 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC>64 ?g/ml), Staphylococcus aureus (MRSA) C623 (MIC>64 ?g/ml).##Yeast: Candida albicans C627 (MIC>64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12878506	Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.	"Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE."	Novel antimicrobial peptides derived from flatfish genes.
DRAMP02374	GCRFCCNCCPNMSGCGVCCRF	21	"Bass hepcidin (fish, chordates, animals)"	P82951	Belongs to the hepcidin family	hamp	Morone chrysops x Morone saxatilis (white bass x striped sea-bass)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Protein level	Beta strand (2 strands; 6 residues)	"Solution structure by NMR indicates that bass hepcidin is very similar to that of human hepcidin, including the presence of an antiparallel beta-sheet, a conserved disulfide-bonding pattern, and a rare vicinal disulfide bond."	1S6W resolved by NMR.	"Function: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages (By similarity). Synthetic bass hepcidin is active in vitro against Gram-negative pathogens and fungi but showes no activity against key Gram-positive pathogens and a single yeast strain tested.
Tissue specificity: Predominantly expressed in liver.
Induction: By bacterial challenge.
PTM: Contains four disulfide bonds 2-19; 5-8; 6-15; 9-18."	"Gram-negative bacteria: Escherichia coli ATCC 25,922,351,50 (MIC=22 ?M), Escherichia coli ATCC D31K (MIC=11 ?M), Klebsiella pneumoniae ATCC 10,031 (MIC=22 ?M), P. shigelloides ATCC KST (MIC=11 ?M), S. flexneri ATCC 12,022 (MIC=22 ?M), Shigella sonnei ATCC 9290 (MIC=44 ?M), Y. enterocolitica ATCC 23,715 (MIC=22 ?M).##Fungi: Aspergillus niger (MIC=44 ?M)."	[Ref.15546886] It displays essentially no hemolytic activity toward HSB erythrocytes	Cyclic	Free	Free	"Disulfide bonds between Cys2 and Cys19; Cys5 and Cys8; Cys6 and Cys15,Cys9 and Cys18."	L	No cytotoxicity information found	Not found	11985602##15546886	Eur J Biochem. 2002 Apr;269(8):2232-2237.##J Biol Chem. 2005 Mar 11;280(10):9272-9282.	"Shike H, Lauth X, Westerman ME, Ostland VE, Carlberg JM, Van Olst JC, Shimizu C, Bulet P, Burns JC.##Lauth X, Babon JJ, Stannard JA, Singh S, Nizet V, Carlberg JM, Ostland VE, Pennington MW, Norton RS, Westerman ME."	"Bass hepcidin is a novel antimicrobial peptide induced by bacterial challenge.##Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections."
DRAMP02391	GWFKKAWRKVKHAGRRVLDTAKGVGRHYLNNWLNRYRG	38	"Hematopoietic antimicrobial peptide-37 (MgCath37; hagfishes, chordates, animals)"	Q71MD7	Not found	CATH37	Myxine glutinosa (Atlantic hagfish)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Propionibacterium acnes ATCC 11827 and 33179 (MIC=2 ?g/ml), Staphylococcus epidermidi (MIC=2-4 ?g/ml), Streptococcus pyogenes (MIC=4 ?g/ml), Enterococcus faecium (MIC=4-8 ?g/ml), Staphylococcus aureus ATCC 29213 (MIC=8 ?g/ml), Clostridium perfringens ATCC 9081 and 13124 (MIC=4-32 ?g/ml), Enterococcus faecalis (MIC=32 ?g/ml);##Gram-negative bacteria: Bacteroides spp. ATCC 29771, 43935, 12290 (MIC=0.5-4 ?g/ml), Shigella sonnei (MIC=2-4 ?g/ml), Xanthomonas maltophilia (MIC=2-8 ?g/ml), Salmonella Group B (MIC=4-8 ?g/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=8 ?g/ml), Acinetobacter baumannii (MIC=8-16 ?g/ml), Escherichia coli ATCC 25922 (MIC=8 ?g/ml), Enterobacter aerogenes (MIC=8-16 ?g/ml), Enterobacter cloacae (MIC=8-16 ?g/ml), Klebsiella pneumoniae (MIC=8-16 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15019197	Peptides. 2003 Nov;24(11):1655-1667.	"Uzzell T, Stolzenberg ED, Shinnar AE, Zasloff M."	Hagfish intestinal antimicrobial peptides are ancient cathelicidins.
DRAMP02393	GFFKKAWRKVKHAGRRVLDTAKGVGRHYVNNWLNRYRZ	38	"HFIAP-1 (HFIAP-2; hagfishes, chordates, animals)"	No entry found	Not found	Not found	Myxine glutinosa (Atlantic hagfish)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Has antibacterial against a bank of Gram-negative and Gram-positive bacteria as well as a representative fungal species.
Sequence similarity: Sequences for HFIAP-1 and -2 are identical, but HFIAP-2 is brominated only at residue 7; they differ from MgCath37 by conservative replacements."	"Gram-positive bacteria: Propionibacterium acnes ATCC 11827/33179 (MIC=2 ?g/ml), Staphylococcus epidermidi (MIC=2-4 ?g/ml), Streptococcus pyogenes (MIC=4 ?g/ml), Enterococcus faecium (MIC=4-8 ?g/ml), Staphylococcus aureus ATCC 29213 (MIC=8 ?g/ml), Clostridium perfringens ATCC 9081/13124 (MIC=4-32 ?g/ml), Enterococcus faecalis (MIC=32 ?g/ml);##Gram-negative bacteria: Bacteroides spp. ATCC 29771/43935/12290 (MIC=0.5-4 ?g/ml), Shigella sonnei (MIC=2-4 ?g/ml), Xanthomonas maltophilia (MIC=2-8 ?g/ml), Salmonella Group B (MIC=4-8 ?g/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=8 ?g/ml), Acinetobacter baumannii (MIC=8-16 ?g/ml), Escherichia coli ATCC 25922 (MIC=8 ?g/ml), Enterobacter aerogenes (MIC=8-16 ?g/ml), Enterobacter cloacae (MIC=8-16 ?g/ml), Klebsiella pneumoniae (MIC=8-16 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15019197	Peptides. 2003 Nov;24(11):1655-1667.	"Uzzell T, Stolzenberg ED, Shinnar AE, Zasloff M."	Hagfish intestinal antimicrobial peptides are ancient cathelicidins.
DRAMP02402	FLPKMSTKLRVPYRRGTKDYH	21	Antimicrobial peptide scolopin-1	P0CH48	Not found	Not found	Scolopendra mutilans (Chinese red-headed centipede) (Scolopendrasubspinipes mutilans)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide against both Gram-positive, Gram-positive and yeast. Also induces histamine release by mast cells and shows hemolytic activities against both human and rabbit red cells.
Tissue specificity: Expressed by the venom gland."	"[Ref.19716842]Gram-negative bacteria: Escherichia coli standard strain (MIC=12.5 ?g/ml), E. coli drug-resistant strain (MIC=15 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus standard strain (MIC=1.2 ?g/ml), S. aureus drug-resistant strain (MIC=5.0 ?g/ml), Bacillus dysenteriae standard and drug-resistant strains (MIC=7.5 ?g/ml);##Yeast: Candida albicans (MIC=15 ?g/ml)."	[Ref.19716842]25 ¡À 2% hemolytic activity at 50 ¦Ìg/ml against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19716842	Toxicon. 2010 Feb-Mar;55(2-3):274-279.	"Peng K, Kong Y, Zhai L, Wu X, Jia P, Liu J, Yu H."	Two novel antimicrobial peptides from centipede venoms.
DRAMP02403	GILKKFMLHRGTKVYKMRTLSKRSH	25	Antimicrobial peptide scolopin-2	P0CH49	Not found	Not found	Scolopendra mutilans (Chinese red-headed centipede) (Scolopendrasubspinipes mutilans)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide against both Gram-positive, -negative and yeast. Also induces histamine release by mast cells and shows hemolytic activities against both human and rabbit red cells.
Tissue specificity: Expressed by the venom gland."	"[Ref.19716842]Gram-negative bacteria: Escherichia coli standard and drug-resistant strains (MIC=5.0 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus standard strain (MIC=0.5 ?g/ml), S. aureus drug-resistant strain (MIC=1.0 ?g/ml), Bacillus dysenteriae standard strain (MIC=2.5 ?g/ml), B. dysenteriae drug-resistant strain (MIC=5.0 ?g/ml);##Yeast: Candida albicans (MIC=7.5 ?g/ml)."	[Ref.19716842]32 ¡À 7% hemolytic activity at 50 ¦Ìg/ml against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19716842	Toxicon. 2010 Feb-Mar;55(2-3):274-279.	"Peng K, Kong Y, Zhai L, Wu X, Jia P, Liu J, Yu H."	Two novel antimicrobial peptides from centipede venoms.
DRAMP02410	FSKYERQKDKRPYSERKNQYTGPQFLYPPERIPPQKVIKWNEEGLPIYEIPGEGGHAEPAAA	62	Antimicrobial peptide lumbricin-1 	O96447	Not found	Not found	Lumbricus rubellus (Humus earthworm)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Displays antimicrobial activity and weak hemolytic activity.
Developmental stage: Adult-specific. Not detected in eggs or 1-week-old worms but abundant in 6-month-old worms.
Induction: Constitutively expressed. Not induced by bacterial infection."	"[Ref.9784609]Gram-positive bacteria: Bacillus subtilis ATCC 62037 (MIC=12 ?g/ml), Staphylococcus aureus ATCC 15752 (MIC=16 ?g/ml), Streptococcus mutans ATCC 25175 (MIC=30 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 27325 (MIC=12 ?g/ml), Pseudomonas putidaATCC 17426 (MIC=16 ?g/ml), Serratia sp. ATCC 21074 (MIC=16 ?g/ml);##Fungi: Candida albicans ATCC 10231 (MIC=16 ?g/ml), Cryptococcus neoformance ATCC 34881 (MIC=25 ?g/ml), Saccharomyces cerevisiae ATCC 44774 (MIC=12 ?g/ml).##NOTE: Minimal inhibitory concentrations were determined by incubating approximately 104¨C105 CFU/ml of cells with serial dilutions of each peptide in a 96-well microtiter plate."	"[Ref.9784609]0.02% hemolytic activity at 5 ¦Ìg/ml, 0.06% hemolytic activity at 10 ¦Ìg/ml, 0.14% hemolytic activity at 25 ¦Ìg/ml, 0.19% hemolytic activity at 50 ¦Ìg/ml, 0.23% hemolytic activity at 100 ¦Ìg/ml against human erythrocytes "	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9784609	Biochim Biophys Acta. 1998 Oct 22;1408(1):67-76.	"Cho JH, Park CB, Yoon YG, Kim SC."	"Lumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization."
DRAMP02423	DFGCARGMIFVCMRRCARMYPGSTGYCQGFRCMCDTMIPIRRPPFIMG	48	"HlMS-defensin (Ticks, Arthropods, animals)"	No entry found	Not found	Not found	Haemaphysalis longicornis (Tick)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=18.8 ?g/ml), Bacillus licheniformis (MIC=9.4 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=28.1 ?g/ml), Pseudomonas aeruginosa ATCC27853 (MIC=37.5 ?g/ml), Serratia rubidaea (MIC=28.1 ?g/ml), Psychrobacter faecalis (MIC=2.3 ?g/ml).##Fungi: Candida albicans ATCC2002 (MIC=18.8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22033149	Dev Comp Immunol. 2012 May;37(1):207-211.	"Zheng H, Zhou L, Yang X, Wang D, Liu J."	Cloning and characterization of a male-specific defensin-like antimicrobial peptide from the tick Haemaphysalis longicornis.
DRAMP02425	QLKVDLWGTRSGIQPEQHSSGKSDVRRWRSRY	32	"Ixosin-B (Ticks, Arthropods, animals)"	A7UDM9	Not found	Not found	Ixodes sinensis (Hard tick)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal and antibacterial activity. Ixosin-B has little hemolytic activity on red blood cells even with peptide
concentrations up to 200 ?g/mL."	[Ref.18295522]Gram-positive bacterium: Staphylococcus aureus (MIC=2.5 ?g/mL);##Gram-negative bacterium: Escherichia coli (MIC=15 ?g/mL);##Yeast: Candida albicans (MIC=7.5 ?g/mL).	[Ref.18295522]Little hemolytic activity on rabbit red blood cells up to 200 ¦Ìg/mL	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18295522	Comp Biochem Physiol B Biochem Mol Biol. 2008 Apr;149(4):557-561.	"Liu Z, Liu H, Liu X, Wu X."	"Purification and cloning of a novel antimicrobial peptide from salivary glands of the hard tick, Ixodes sinensis."
DRAMP02430	GLHKVMREVLGYERNSYKKFFLR	23	"Ixosin (Ticks, Arthropods, animals)"	Q2LKX9	Not found	Not found	Ixodes sinensis (Hard tick)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity against C. albicans. Has antibacterial activity against the Gram-positive bacterium S. aureus and the Gram-negative bacterium E. coli. Little hemolytic activity against rabbit erythrocytes.	[Ref.16087274]Gram-postive bacteria: Staphylococcus aureus (MIC=3.7 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=30 ?g/ml);##Fungi: Candida albicans (MIC=7.5 ?g/ml).	[Ref.16087274]Little hemolytic activity on rabbit red blood cells up to 50 ¦Ìg/mL	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16087274	Peptides. 2006 Jan;27(1):31-5.	"Yu D, Sheng Z, Xu X, Li J, Yang H, Liu Z, Rees HH, Lai R."	"A novel antimicrobial peptide from salivary glands of the hard tick, Ixodes sinensis."
DRAMP02433	HHQELCTKGDDALVTELECIRLRISPETNAAFDNAVQQLNCLNRACAYRKMCATNNLEQAMSVYFTNEQIKEIHDAATACDPEAHHEHDH	90	"Antimicrobial peptide microplusin (Microplusin; Ticks, Arthropods, animals)"	Q86LE5	Not found	Not found	Boophilus microplus (Cattle tick)	"Antimicrobial, Antifungal, Antibacterial"	Protein level	Alpha helix 	"Microplusin consists of five alpha-helices: alpha1 (residues Gly-9 to Arg-21), alpha2 (residues Glu-27 to Asn-40), alpha3 (residues Arg-44 to Thr-54), alpha4 (residues Leu-57 to Tyr-64), and alpha5 (residues Asn-67 to Cys-80). The N and C termini are disordered."	2KNJ?resolved by NMR.	"Function: Has bacteriostatic activity against the Gram-positive bacterium M.luteus. Has fungistatic activity against C.neoformans. Binds and sequesters copper and iron ions. Copper-chelating is crucial for antimicrobial activity against M.luteus.
Tissue specificity: Expressed in the hemocytes, fat body and ovaries.
PTM: Contains three disulfide bonds 6-52; 19-80; 41-46."	"Micrococcus luteus (MIC=0.38-0.76 ?M), Cryptococcus neoformans."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys6 and Cys52,Cys19 and Cys80,Cys41 and Cys46."	L	No cytotoxicity information found	Metal-binding: copper II and iron II	14642886##19828445	Dev Comp Immunol. 2004 Mar;28(3):191-200.##J Biol Chem. 2009 Dec 11;284(50):34735-34746.	"Foga?a AC, Lorenzini DM, Kaku LM, Esteves E, Bulet P, Daffre S.##Silva FD, Rezende CA, Rossi DC, Esteves E, Dyszy FH, Schreier S, Gueiros-Filho F, Campos CB, Pires JR, Daffre S."	"Cysteine-rich antimicrobial peptides of the cattle tick Boophilus microplus: isolation, structural characterization and tissue expression profile.##Structure and mode of action of microplusin, a copper II-chelating antimicrobial peptide from the cattle tick Rhipicephalus (Boophilus) microplus."
DRAMP02439	FTCAISCDIKVNGKPCKGSGEKKCSGGWSCKFNVCVKV	38	U-theraphotoxin-Aju1a (U-TRTX-Aju1a; Juruin)	B3EWQ0	Belongs to the huwentoxin-2 family	Not found	Avicularia juruensis (Yellow-banded pinktoe)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has strong antifungal activity. Has no hemolytic activity against human erythrocytes. Probable ion channel inhibitor (By similarity).
Tissue specificity: Expressed by the venom gland.
PTM: Contains three disulfide bonds 3-24; 7-30; 16-35."	"[Ref. Front.Microbiol.2012 Sep;3:324-324.]Fungi: Candida albicans MDM8, C. albicans IOC 45588 (MIC=2.5-5 ?M), C. krusei IOC 4559 (MIC=2.5-5 ?M), C. glabrata IOC 45658 (MIC=2.5-5 ?M), C. parapsilosis IOC 456416 (MIC=2.5-5 ?M), C. tropicalis IOC 45608 (MIC=2.5-5 ?M), C. guilliermondii IOC 455716 (MIC=2.5-5 ?M) and Aspergillus niger (MIC=5-10 ?M)"	[Ref. 22973266] It has no hemolytic activity at 10¦ÌM against human human erythrocytes	Cyclic	Free	Free	"Disulfide bonds between Cys3 and Cys24,Cys7 and Cys30,Cys16 and Cys35."	L	No cytotoxicity information found	Not found	PubMed ID is not available	Front. Microbiol. 2012 Sep;3:324-324.	"Ayroza G, Ferreira ILC, Sayegh RSR, Tashima AK, Silva jr PI."	"Juruin: an antifungal juruentoxin peptide from the venom of the amazonian pink toe spider, Avicularia juruensis, which contains the inhibitory cystine knot motif."
DRAMP02449	TGVAWRIT	8	Lectin	P86922	Not found	Not found	Ganoderma lucidum (Ling zhi medicinal fungus) (Bracket fungus)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has metal-independent hemagglutinating activity against erythrocytes from human, sheep, goat, rat, rabbit and chicken. Hemagglutinating activity is inhibited by glycoproteins fetuin, asialo-fetuin, fibrinogen, asialo-fibrinogen, thyroglobulin, bovine (BSM) as well as porcine submaxillary mucin and asialo-BSM but not by sugars alpha-L-fucose, D-glucose, D-galactose, D-glucosamine, D-galactosamine, lactose, D-melibiose, D/L-mannose, D-mannosamine, D-raffinose, L-rhamnose, xylose, glacaturonic acid or N-acetylglucosamine. Has antifungal activity. 
Biophysicochemical properties: pH dependence (Hemagglutinating activity is stable from pH 4 to pH 9 but drops sharply below pH 4 and above pH 9); Temperature dependence (Hemagglutinating activity is stable below 60 degrees Celsius but drops sharply to about 20% at 80 degrees Celsius)."	"Fungi: Fusarium oxysporum (MIC=20 ?g/ml), Penicillium chrysogenum (MIC=35 ?g/ml), Aspergillus niger (MIC=50 ?g/ml), Cladosporium musae (MIC=60 ?g/ml), Botrytis cinerea (MIC=65 ?g/ml), Trichophyton rubrum (MIC=65 ?g/ml), T. tonsurans (MIC=20 ?g/ml), T. interdigitale (MIC=20 ?g/ml), Epidermophyton floccosum (MIC=15 ?g/ml), Microsporum canis (MIC=70 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21728991	Protein Pept Lett. 2011 Nov;18(11):1150-1157.	"U Girjal V, Neelagund S, Krishnappa M."	Ganoderma lucidum: A source for novel bioactive lectin.
DRAMP02473	KFFRKLKKSVKKRAKEFFKKPRVIGVSIPF	30	"Cathelicidin-BF (Cathelicidin-related protein; Snakes, reptiles, animals)"	B6D434	Not found	Not found	Bungarus fasciatus (Banded krait)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Adopts an amphipathic alpha helical conformation, that may allow to partition into the target membrane. No hemolytic and cytotoxic activities have been observed on mammalian cells.
Tissue specificity: Expressed by the venom gland, stomach, trachea, skin, muscle, heart, kidney, lung, brain, intestine, spleen, liver, and ovary.
Miscellaneous: A predicted cleavage site is located at position Val-157-158-Lys, giving a peptide of 34 residues instead of the 30 residues found for the purified protein. The 30 residues cathelicidin-BF could result from a further processing."	"[Ref.18795096]Gram-negative bacteria: Pseudomonas aeruginosa ATCC27853 (MIC=1.2 ?g/ml), P. aeruginosa IS/DR (MIC=2.3 ?g/ml), P. aeruginosa 08031205 IS/DR (MIC=9.4 ?g/ml), P. aeruginosa 08031014 IS/DR (MIC=18.7 ?g/ml), Escherichia coli ATCC25922 (MIC=2.3 ?g/ml), E. coli 08A852 IS/DR (MIC=1.2 ?g/ml), E. coli 08A866 IS/DR (MIC=0.6 ?g/ml), E. coli 08031017 IS/DR (MIC=2.3 ?g/ml), E. coli 08032813 IS/DR (MIC=2.3 ?g/ml), E. coli 08040726 IS/DR (MIC=0.6 ?g/ml), E. coli 08040722 IS/DR (MIC=0.6 ?g/ml), Klebsiella pneumoniae IS/DR (MIC=4.7 ?g/ml), K. pneumoniae 08031012 IS/DR (MIC=9.4 ?g/ml), K. pneumoniae 08040202 IS/DR (MIC=0.6 ?g/ml), K. pneumoniae 08040724 IS/DR (MIC=0.3 ?g/ml), Pseudomonas luteola (MIC=1.2 ?g/ml), Salmonella Typhi IS/DR (MIC=1.2 ?g/ml), Acinetobacter calcoaceticus (MIC=2.3 ?g/ml), Sphingobacterium siyangense (MIC=9.4 ?g/ml), Saccharibacillus kuerlensis (MIC=4.7 ?g/ml);##Gram-positive bacteria: Bacillus subtilis (MIC=9.4 ?g/ml), B. pumilus (MIC=9.4 ?g/ml), B. cereus (MIC=1.2 ?g/ml), Staphylococcus aureus ATCC2592 (MIC=4.7 ?g/ml), S. aureus 08A875 IS/DR (MIC=75 ?g/ml), S. aureus 08031002 IS/DR (MIC>100 ?g/ml), S. aureus 08031013 IS/DR (MIC>100 ?g/ml), S. aureus 08032706 IS/DR (MIC>100 ?g/ml), S. aureus 08032712 IS/DR (MIC>100 ?g/ml), S. aureus 08032810 IS/DR (MIC>100 ?g/ml), Enterococcus faecium IS/DR (MIC=150 ?g/ml);##Fungi: Aspergillus terreus GIM3.34 (MIC=18.7 ?g/ml), Aspergillus nidulans (MIC=18.7 ?g/ml), Candida albicans ATCC2002 (MIC=4.7 ?g/ml), Pichia pastoris (MIC=0.3 ?g/ml)."	[Ref.18795096]Non-hemolytic activity at 400 ?g/ml against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	18795096##18620012	PLoS One. 2008 Sep 16;3(9):e3217.##Peptides. 2008 Oct;29(10):1685-1691.	"Wang Y, Hong J, Liu X, Yang H, Liu R, Wu J, Wang A, Lin D, Lai R.##Zhao H, Gan TX, Liu XD, Jin Y, Lee WH, Shen JH, Zhang Y."	Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics.##Identification and characterization of novel reptile cathelicidins from elapid snakes.
DRAMP02474	KFFRKLKKSVKKRAK	15	"cathelicidin-BF15 (Snakes, reptiles, animals)"	B6D434	Not found	Not found	Bungarus fasciatus (Banded krait)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Pseudomonas aeruginosa ATCC27853 (MIC=4.7 ?g/ml), P. aeruginosa IS/DR (MIC=37.5 ?g/ml), P. aeruginosa 08031205 IS/DR (MIC=18.7 ?g/ml), P. aeruginosa 08031014 IS/DR (MIC=75 ?g/ml), Escherichia coli ATCC25922 (MIC=18.7 ?g/ml), E. coli 08A852 IS/DR (MIC=18.7 ?g/ml), E. coli 08A866 IS/DR (MIC=18.7 ?g/ml), E. coli 08031017 IS/DR (MIC=37.5 ?g/ml), E. coli 08040722 IS/DR (MIC=9.4 ?g/ml), K. pneumoniae 08040202 IS/DR (MIC=75 ?g/ml), Salmonella Typhi IS/DR (MIC=1.2 ?g/ml), Saccharibacillus kuerlensis (MIC=4.7 ?g/ml).##Gram-positive bacteria: Bacillus subtilis (MIC=75 ?g/ml), Staphylococcus aureus ATCC2592 (MIC=75 ?g/ml), S. aureus 08A875 IS/DR (MIC=75 ?g/ml), S. aureus 08031002 IS/DR (MIC>100 ?g/ml).##Fungi: Candida albicans ATCC2002 (MIC=18.7 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18795096	PLoS One. 2008 Sep 16;3(9):e3217.	"Wang Y, Hong J, Liu X, Yang H, Liu R, Wu J, Wang A, Lin D, Lai R."	Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics.
DRAMP02573	QVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYS	62	"Penaeidin-3a (Pen-3a; shrimps, Arthropods, animals)"	P81058	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Tissue specificity: Higher expression in hemocytes and to a lesser extent in heart, testis, gills, intestine, lymphonoid organ and hepatopancreas. Traces in eyes and subcuticular epithelium. Not present in the brain.
Developmental stage: Expression decreases 3 hours after microbial challenge to return to control levels after 12 hours and slightly increases after 24 hours.
PTM: C-terminal amidation and contains three disulfide bonds 32-47; 36-54; 48-55."	"Gram-positive bacteria: Aerococcus viridans (MIC=0.3-0.6 ?M), Micrococcus luteus (MIC=1.25-2.5 ?M), Bacillus megaterium (MIC=2.5-5 ?M), Enterococcus fecalis (MIC>20 ?M), Saphylococcus aureus (MIC>40 ?M);##Gram-negative bacteria: Escherichia coli 363 (MI=10-20 ?M), Vibrio vulnificus (MIC>20 ?M), Salmonella thyphimurium (MIC>40 ?M), Klebsiella pneumoniae (MIC>40 ?M).##Fungi: Fusarium oxysporum (MIC=5-10 ?M), Botrytis cinerea (MIC=5-10 ?M), Neurospora crassa (MIC=1.25-2.5 ?M), Aspergillus fumigatus (MIC>20 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	pyroglutamic acid	Amidation	"Disulfide bonds between Cys32 and Cys47,Cys36 and Cys54,Cys48 and Cys55. O-glycosylated on Thr8"	L	No cytotoxicity information found	Chitin-binding	9353298##10561573##12842879	J Biol Chem. 1997 Nov 7;272(45):28398-28406.##Eur J Biochem. 1999 Dec;266(2):335-346.##J Biol Chem. 2003 Sep 19;278(38):36859-36867.	"Destoumieux D, Bulet P, Loew D, Van Dorsselaer A, Rodriguez J, Bach¨¨re E.##Destoumieux D, Bulet P, Strub JM, Van Dorsselaer A, Bach¨¨re E.##Yang Y, Poncet J, Garnier J, Zatylny C, Bach¨¨re E, Aumelas A."	"Penaeidins, a new family of antimicrobial peptides isolated from the shrimp Penaeus vannamei (Decapoda).##Recombinant expression and range of activity of penaeidins, antimicrobial peptides from penaeid shrimp.##Solution structure of the recombinant penaeidin-3, a shrimp antimicrobial peptide."
DRAMP02574	QVYKGGYARPIPRPPPFVRPLPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYSG	63	"[T8A]-Penaeidin-3a ([T8A]-Pen-3a; shrimps, Arthropods, animals)"	P81058	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix (1 helices; 11 residues)	"[T8A]-Pen-3a structure consists of an unconstrained and a constrained part, which roughly match with the proline-rich (1-28 residues) and the cysteine-rich (29-58 residues) domains, respectively. The proline-rich domain does not adopt a constrained structure, whereas the cysteine-rich domain adopts a well-defined structure that consists of a helix (41-50 residues) tightly bound to the upstream (27-40 residues) and the downstream (51-63 "	1UEO resolved by NMR.	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
PTM: Contains three disulfide bonds."	"Gram-positive bacteria: Aerococcus viridans (MIC=0.4-0.8 ?M), Micrococcus luteus (MIC=0.8-1.6 ?M), Bacillus megaterium (MIC=3.12-6.25 ?M);##Gram-negative bacteria: Escherichia coli 363 (MI=3.12-6.25 ?M), Vibrio vulnificus (MIC>50 ?M), Salmonella thyphimurium (MIC>50 ?M), Klebsiella pneumoniae (MIC>50 ?M).##Fungi: Fusarium oxysporum (MIC=3.12-6.25 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	pyroglutamic acid	Amidation	"Disulfide bonds between Cys32 and Cys47,Cys36 and Cys54,Cys48 and Cys55. O-glycosylated on Thr8"	L	No cytotoxicity information found	Not found	12842879	J Biol Chem. 2003 Sep 19;278(38):36859-36867.	"Yang Y, Poncet J, Garnier J, Zatylny C, Bach¨¨re E, Aumelas A."	"Solution structure of the recombinant penaeidin-3, a shrimp antimicrobial peptide."
DRAMP02584	HSSGYTRPLPKPSRPIFIRPIGCDVCYGIPSSTARLCCFRYGDCCHR	47	"Penaeidin-4a (Pen-4a; shrimps, Arthropods, animals)"	Q95NT0	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity (By similarity).
PTM: Contains three disulfide bonds 23-37; 26-44; 38-45 and C-terminal amidation."	"Gram-positive bacteria: Aerococcus viridans (MIC=1.9-2.92 ?M), Micrococcus luteus (MIC=1.9-2.92 ?M), Bacillus megaterium (MIC>50 ?M), Saphylococcus aureus (MIC>50 ?M);##Gram-negative bacteria: Escherichia coli 363 (MIC=22-33 ?M), Vibrio vulnificus (MIC>50 ?M), Salmonella thyphimurium (MIC>50 ?M), Klebsiella pneumoniae (MIC>50 ?M).##Fungi: Fusarium oxysporum (MIC=0.84-1.26 ?M), Botrytis cinerea (MIC=4.38-6.57 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Amidation	"Disulfide bonds between Cys23 and Cys37,Cys26 and Cys44,Cys38 and Cys45."	L	No cytotoxicity information found	Chitin-binding	12242595##15084144	Immunogenetics. 2002 Sep;54(6):442-445.##Biochem J. 2004 Jul 1;381(Pt 1):79-86.	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS.##Cuthbertson BJ, Bullesbach EE, Fievet J, Bach¨¨re E, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.##A new class (penaeidin class 4) of antimicrobial peptides from the Atlantic white shrimp (Litopenaeus setiferus) exhibits target specificity and an independent proline-rich-domain function.
DRAMP02586	QRGGFTGPIPRPPPHGRPPLGPICNACYRLSFSDVRICCNFLGKCCHLVK	50	"Penaeidin-2d (Pen-2d; shrimps, Arthropods, animals)"	Q962A9	Belongs to the penaeidin family	Not found	Litopenaeus setiferus (Atlantic white shrimp) (Penaeus setiferus)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	"Function: Antibacterial and antifungal activity. Presents chitin-binding activity (By similarity).
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser."	"Gram-positive bacteria: Aerococcus viridans (MIC=1.25-2.5 ?M), Micrococcus luteus (MIC=2.5-5 ?M), Bacillus megaterium (MIC=2.5-5 ?M), Enterococcus fecalis (MIC>20 ?M), Saphylococcus aureus (MIC>20 ?M);##Gram-negative bacteria: Escherichia coli 363 (MIC>40 ?M), Vibrio vulnificus (MIC>20 ?M), Salmonella thyphimurium (MIC>20 ?M), Klebsiella pneumoniae (MIC>20 ?M).##Fungi: Fusarium oxysporum (MIC=5-10 ?M), Botrytis cinerea (MIC=5-10 ?M), Neurospora crassa (MIC=2.5-5 ?M), Aspergillus fumigatus (MIC>20 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595##10561573	Immunogenetics. 2002 Sep;54(6):442-445.##Eur J Biochem. 1999 Dec;266(2):335-346.	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS.##Destoumieux D, Bulet P, Strub JM, Van Dorsselaer A, Bach¨¨re E."	"Diversity of the penaeidin antimicrobial peptides in two shrimp species.##Recombinant expression and range of activity of penaeidins, antimicrobial peptides from penaeid shrimp."
DRAMP02591	HSSGYTRPLRKPSRPIFIRPIGCDVCYGIPSSTARLCCFRYGDCCHL	47	"Penaeidin-4d (Pen-4d; shrimps, Arthropods, animals)"	Q962A7	Belongs to the penaeidin family	Not found	Litopenaeus setiferus (Atlantic white shrimp) (Penaeus setiferus)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Alpha helix (1 helices; 9 residues)	"Calculation of PEN4 three-dimensional structure reveales that the PEN4 structure consisted of an unconstrained and a constrained part, which roughly match with the PRD (residues 1-17) and the CRD (residues 18-47), respectively. The global fold of the CRD mainly consisted of a helix (residues 31-41), two turns of type IV (Cys23-Cys26 and Gly42-Cys45 residues), and one loop spanning 27-30 residues (Ref.2)."	1XV3 resolved by NMR.	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity (By similarity).
PTM: Contains three disulfide bonds 23-37; 26-44; 38-45."	"Fungi: Fusarium oxysporum (MIC=0.84-1.26 ?M), Botrytis cinerea (MIC=4.38-6.57 ?M), Penicillium crustosum (MIC=1.26-1.9 ?M).## Gram-positive bacteria: Aerococcus viridans (MIC=1.9-2.92 ?M), Bacillus megaterium (MIC>50 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595##15699044	Immunogenetics. 2002 Sep;54(6):442-445.##J Biol Chem. 2005 Apr 22;280(16):16009-18.	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS.##Cuthbertson BJ, Yang Y, Bach¨¨re E, B¨¹llesbach EE, Gross PS, Aumelas A."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.##Solution structure of synthetic penaeidin-4 with structural and functional comparisons with penaeidin-3.
DRAMP02603	AALRGALRAVARVGKAILPHVAIANPYVRTPYVHNNP	37	"Putative antimicrobial peptide A Northern Europe Heligoland (chordates, animals)"	No entry found	Not found	Not found	Ciona intestinalis 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus megaterium (MIC=0.1 ?M), Bacillus subtilis (MIC=3.1 ?M), Staphylococcus aureus (MIC>25 ?M), Staphylococcus epidermidis (MIC=25 ?M).##Gram-negative bacteria: Escherichia coli K12 D31 (MIC=0.8 ?M), Y. enterocolitica (MIC=3.1 ?M), Klebsiella pneumoniae (MIC>25?M), Pseudomonas aeruginosa (MIC=12.5 ?M), Serratia marcescens(MIC>25 ?M).##Fungi: Candida albicans ATCC 10261 (MIC=6.3 ?M), Candida albicans SC 5314 (MIC=6.3 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17658598	Dev Comp Immunol. 2008;32(3):286-298. 	"Fedders H, Leippe M."	A reverse search for antimicrobial peptides in Ciona intestinalis: identification of a gene family expressed in hemocytes and evaluation of activity.
DRAMP02609	RLGDILQKAREKIEGGLKKLVQKIKDFFGKFAPRTES	37	"CjaRL-37 (cathelicidin; primates, mammals, animals)"	No entry found	Not found	Not found	Platyrrhini (New World monkeys)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial activity.	"In 20% TSB in SPB medium: Escherichia coli (MIC=4 ?M), Pseudomonas aeruginosa (MIC>32 ?M); Staphylococcus aureus (MIC=32 ?M), Enterococcus faecalis (MIC>32 ?M).##In 20% SAB in SPB medium: Candida albicans (MIC>32 ?M). In 5% SAB in SPB Candida albicans (MIC>32 ?M). In 20% SAB in PIL Candida albicans (MIC>32 ?M).##In 5% TSB in SPB Escherichia coli (MIC=1 ?M), Pseudomonas aeruginosa (MIC=2 ?M), Staphylococcus aureus (MIC=8-16 ?M).##In 20% TSB in PIL Escherichia coli (MIC>32 ?M), Pseudomonas aeruginosa (MIC>32 ?M); Staphylococcus aureus (MIC=16 ?M), Enterococcus faecalis (MIC>32 ?M).##In 50% MH in SPB medium Escherichia coli (MIC>32 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16720578	J Biol Chem. 2006 Jul 21;281(29):19861-19871.	"Zelezetsky I, Pontillo A, Puzzi L, Antcheva N, Segat L, Pacor S, Crovella S, Tossi A."	Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity.
DRAMP02727	SLGNFFRKARKKIGEEFKRIVQRIKDFLQHLIPRTEA	37	"HmdSL-37 (cathelicidin; primates, mammals, animals)"	No entry found	Not found	Not found	Hylobates sp. (Gibbon)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial activity.	"In 20% TSB in SPB medium Escherichia coli (MIC=2 ?M), Pseudomonas aeruginosa (MIC=8 ?M), Staphylococcus aureus (MIC>32 ?M), Enterococcus faecalis (MIC=8 ?M).##In 20% SAB in SPB Candida albicans (MIC>32 ?M). In 5% SAB in SPB Candida albicans (MIC=8 ?M). In 20% SAB in PIL Candida albicans (MIC>32 ?M).##In 5% TSB in SPB Escherichia coli (MIC=1 ?M), Pseudomonas aeruginosa (MIC=2 ?M), Staphylococcus aureus (MIC=2 ?M).##In 20% TSB in PIL Escherichia coli (MIC>32 ?M), Pseudomonas aeruginosa (MIC=16-32 ?M); Staphylococcus aureus (MIC=8-16 ?M), Enterococcus faecalis (MIC>32 ?M).##In 50% MH in SPB medium Escherichia coli (MIC>32 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16720578	J Biol Chem. 2006 Jul 21;281(29):19861-19871.	"Zelezetsky I, Pontillo A, Puzzi L, Antcheva N, Segat L, Pacor S, Crovella S, Tossi A."	Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity.
DRAMP02740	YDLSKNCRLRGGICYIGKCPRRFFRSGSCSRGNVCCLRFG	40	"TBD-1 (Turtle beta-defensin 1; Reptiles, animals)"	P86253	Belongs to the beta-defensin family	Not found	Emys orbicularis (European pond turtle)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against the Gram-positive bacteria methicillin-resistant S. aureus ATCC 33591 and L. monocytogenes EGD, the Gram-negative bacterium E. coli ML53p and the yeast C. albicans 820. Has no hemolytic activity towards human erythrocytes.
PTM: Contains three disulfide bonds 7-35; 14-29; 19-36."	"[Ref.19253295]Gram-negative bacterium (LS, HS): Escherichia coli ML35p (MIC=0.65, >20 ?mol/L);##Gram-positive bacteria: (LS, HS): Listeria monocytogenes EGD (MIC=0.65, >20 ?mol/L), Methicillin-resistant Staphylococcus aureus ATCC 33591 (MIC=5.6, >20 ?mol/L).##Yeast: Candida albicans (MIC=5.2, >20 ?mol/L).##NOTE: LS (low salt): 10 mmol/L sodium phosphate buffer (pH 7.4) and HS (high salt): 10 mmol/L sodium-phosphate buffer (pH 7.4), 0.1 mol/L sodium chloride."	[Ref.19253295] It has no hemolytic activity against human erythrocytes up to 25 mmol/L	Cyclic	Free	Free	Disulfide bonds between Cys7 and Cys35; Cys14 and Cys29; Cys19 and Cys36.	L	No cytotoxicity information found	Not found	19253295	Proteomics. 2009 Mar;9(5):1364-1373.	"Stegemann C, Kolobov A Jr, Leonova YF, Knappe D, Shamova O, Ovchinnikova TV, Kokryakov VN, Hoffmann R."	"Isolation, purification and de novo sequencing of TBD-1, the first beta-defensin from leukocytes of reptiles."
DRAMP02768	GLGSVFGRLARILGRVIPKVAKKLGPKVAKVLPKVMKEAIPMAVEMAKSQEEQQPQ	56	"Pilosulin-1 (Myr b I; ants, insects, animals)"	"Q07932, Q9TWC1"	Belongs to the pilosulin family	Not found	Myrmecia banksi (Jack jumper ant) (Australian jumper ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Has strong cytotoxic and hemolytic activities. Is more potent against mononuclear leukocytes than against granulocytes. The synthesized peptide 57-76 shows a potent and broad spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria, and also against the fungus C. albicans. Adopts an alpha-helical structure.
Tissue specificity: Expressed by the venom gland.
Allergenic properties: Causes an allergic reaction in human."	"[Ref.9813247]Gram-positive bacteria: Micrococcus luteus (MIC=0.5 ?M), Enterococcus spp.I-11305b (MIC=2 ?M), Enterococcus spp. I-11054 (MIC=2 ?M), Staphylococcus simulans 22 (MIC=2 ?M), S. haemolyticus I-10925 (MIC=2 ?M), S. epidermidis LT1324 (MIC=2 ?M), S. aureuss 5185 (MI=2 ?M), S. aureuss methicillin-sensitive I-11574 (MIC=2 ?M), S. aureuss (MRSA) LT1338 (MIC=3 ?M), S. aureuss (MRSA) LT1334 (MIC=1.5 ?M);##Gram-negative bacteria: Citrobacter freundii I-11090 (MIC=2 ?M), Klebsiella pneumoniae I-10910 (MIC=2 ?M), Escherichia coli I-11276b (MIC=4 ?M), E. coli O-19592 (MIC=2 ?M), Stenotrophomonas maltophilia O-16451 (MIC=2 ?M), S. maltophila I-10717 (MIC=2 ?M), Pseudomonas aeruginosa 4991 (MIC=4 ?M), Pseudomonas aeruginosa I-10968 (MIC=4 ?M);##Fungi: Candida albicans I-11301 (MIC=4 ?M), Candida albicans I-11134 (MIC>4 ?M)."	[Ref.9813247]Complete lysis in the presence of pilosulin 1 was obtained at a concentration of 40 ¦ÌM with evidence of partial lysis visible down to 1.25 ¦ÌM	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	IgE	9813247##9701394##15639237##8866004	Arch Biochem Biophys. 2005 Feb 15;434(2):358-364.##Cytometry. 1998 Aug 1;32(4):268-273.##Arch Biochem Biophys. 2005 Feb 15;434(2):358-364.##Biochem Mol Biol Int. 1996 Aug;39(5):877-885.	"Zelezetsky I, Pag U, Antcheva N, Sahl HG, Tossi A.##King MA, Wu QX, Donovan GR, Baldo BA.##Zelezetsky I, Pag U, Antcheva N, Sahl HG, Tossi A.##Donovan GR, Street MD, Tetaz T, Smith AI, Alewood D, Alewood P, Sutherland SK, Baldo BA."	Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin.##Flow cytometric analysis of cell killing by the jumper ant venom peptide pilosulin 1.##Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin.##Expression of jumper ant (Myrmecia pilosula) venom allergens: post-translational processing of allergen gene products.
DRAMP02774	CIKNGNGCQPDGSQGNCCSRYCHKEPGWVAGYCR	34	"Antimicrobial peptide Alo-1 (Alo-1; knottin-type peptide; Insects, animals)"	P83651	Belongs to the AMP family	Not found	Acrocinus longimanus (Giant harlequin beetle)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Has antifungal activity against C. glabrata.
Domain: The presence of a disulfide through disulfide knot' structurally defines this protein as a knottin.
PTM: Contains three disulfide bonds 1-18; 8-22; 17-33."	"Fungi: Candida glabrata patient 1 (MIC>64 ?g/mL), C. albicans IHEM 8060 (MIC=64 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bonds between Cys1 and Cys18; Cys8 and Cys22; Cys17 and Cys33.	L	No cytotoxicity information found	Not found	14661954	Biochemistry. 2003 Dec 16;42(49):14434-14442.	"Barbault F, Landon C, Guenneugues M, Meyer JP, Schott V, Dimarcq JL, Vovelle F."	Solution structure of Alo-3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus.
DRAMP02776	CIKNGNGCQPNGSQGNCCSGYCHKQPGWVAGYCRRK	36	"Antimicrobial peptide Alo-3 (Alo-3; knottin-type peptide; Insects, animals)"	P83653	belongs to the inhibitor cystine-knot family	Not found	Acrocinus longimanus (Giant harlequin beetle)	"Antimicrobial, Antifungal"	Protein level	Beta strand (3 strands; 8 residues)	"Alo-3 contains six cysteine residues forming three disulfide bridges. It exhibits all the structural features characteristic of the knottin fold, namely, a triple-stranded antiparallel beta-sheet with a long flexible loop connecting the first strand to the second strand and a series of turns."	1Q3J resolved by NMR.	"Function: Alo-3 shows a level of activity significantly higher against C. glabrata than Alo-1 or Alo-2.
Domain: The presence of a disulfide through disulfide knot' structurally defines this protein as a knottin.
PTM: Contains three disulfide bonds 1-18; 8-22; 17-33."	"Fungi: Candida glabrata patient 1 (MIC=8 ?g/mL), C. glabrata ATCC 90030 (MIC=16 ?g/mL), C. albicans IHEM 8060 (MIC=16 ?g/mL), C. albicans ATCC 36082 (MIC=8 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bonds between Cys1 and Cys18; Cys8 and Cys22; Cys17 and Cys33.	L	No cytotoxicity information found	Not found	14661954	Biochemistry. 2003 Dec 16;42(49):14434-14442.	"Barbault F, Landon C, Guenneugues M, Meyer JP, Schott V, Dimarcq JL, Vovelle F."	Solution structure of Alo-3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus.
DRAMP01623	LIGPVLGLVGSALGGLLKKI	20	"Bombinin-H4 (bombinin H isomers; Frogs, amphibians, animals)"	P82284	Belongs to the bombinin family	Not found	Bombina variegata (European frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, hemolytic against mammalian cells, Antifungal"	Protein level	Alpha helix	"The epimerization reaction is incomplete, or, after racemization, the peptides still containing the L-amino acid in position 2 are partly degraded."	None	Function: Have antimicrobial activity. Have some hemolytic activity.	[Ref.8223491] Gram-negative bacterium: Escherichia coli D21 (MIC=4.8 ?M);##Gram-positive bacterium: Staphylococcus aureus Cowan 1 (MIC=3.3 ?M).	[Ref.8223491] Lethal concentration is 14.6 ?M against human red blood cell.	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8223491	EMBO J. 1993; 12:4829-4832.	"Mignogna G, Simmaco M, Kreil G, Barra D.1993"	Antibacterial and haemolytic peptides containing D-alloisoleucine from the skin of Bombina variegata.
DRAMP02802	AREASKSLIGTASCTCRRAWICRWGERHSGKCIDQKGSTYRLCCRR	46	"Paneth cell-specific alpha-defensin 1 (DEFA1; horse defensin; houses, mammals, animals"	A6YB85	Not found	DEFA1	Equus caballus (Horse)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	2MXQ resolved by NMR.	Function: Membrane permeabilization is at least an essential part of the peptide's mode of action.	"Gram-negative bacteria: Escherichia coli [ATCC 11775 (MBC=0.4 ?M); ATCC 25922 (MBC=0.4 ?M); ATCC 35218 (MBC=0.4 ?M)], E. coli D31 (MBC=0.8 ?M), Pseudomonas aeruginosa ATCC 11440 (MBC=3 ?M);##Gram-positive bacteria: Staphylococcus aureus [ATCC 6538 (MBC=0.8 ?M); ATCC 12600 (MBC=1.5 ?M)], Staphylococcus epidermidis ATCC 14990 (MBC=1.5 ?M), Enterococcus faecalis ATCC 29212 (MBC=6.1 ?M), E. faecalis PEG 205 (wild-type) (MBC=3 ?M), Streptococcus pyogenes ATCC 12344 (MBC=0.8 ?M), Bacillus megaterium ATCC 14581 (MBC=0.2 ?M).##Yeast: Candida albicans ATCC 24433 (MIC=0.8 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bonds between Cys14 and Cys44; Cys16 and Cys32; Cys22 and Cys43.	L	No cytotoxicity information found	Not found	17620056	Biochem J. 2007 Oct 15;407(2):267-276.	"Bruhn O, Regenhard P, Michalek M, Paul S, Gelhaus C, Jung S, Thaller G, Podschun R, Leippe M, Gr?tzinger J, Kalm E."	"A novel horse alpha-defensin: gene transcription, recombinant expression and characterization of the structure and function."
DRAMP02809	HPHVCTSYYCSKFCGTAGCTRYGCRNLHRGKLCFCLHCSR	40	"Myticin-B (Myt B; Cys-rich; molluscas, animals)"	P82102	Not found	Not found	Mytilus galloprovincialis (Mediterranean mussel)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Rich	Not found	None	"Function: Bacteriolytic activity against Gram-positive bacteria and Gram-negative bacteria. Also possesses antifungal activity against F. oxysporum.
PTM: contains four disulfide bonds."	"Gram-positive bacteria: Micrococcus luteus (MBC=1-2 ?M), Bacillus megaterium (MBC=1-2 ?M), Aerococcus viridans (MBC=2-4 ?M).##Gram-negative bacteria: Escherichia coli D31 (MBC=20-10 ?M).##Fungi: Fusarium oxysporum (MIC=5-10 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	contains four disulfide bonds.	L	No cytotoxicity information found	Not found	10491159	Eur J Biochem. 1999 Oct 1;265(1):71-78.	"Mitta G, Hubert F, No?l T, Roch P."	"Myticin, a novel cysteine-rich antimicrobial peptide isolated from haemocytes and plasma of the mussel Mytilus galloprovincialis."
DRAMP01381	GLFTLIKGAAKLIGKTVPKKQARLGMNLWLVKLPTNVKT	39	"Odorranain-K1 (OdK1; Frogs, amphibians, animals)"	A6MBN8	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	Function: Odorranain-K1 exhibites antimicrobial activities against all of the tested microbes including Gram-positive and Gram-negative bacteria and fungi.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=4.68 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=4.68 ¦Ìg/ml), Bacillus subtilis (MIC=1.10 ¦Ìg/ml).##Yeast: Candida albicans (MIC=1.10 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01383	ATAWDFGPHGLLPIRPIRIRPLCGKDKS	28	"Odorranain-M1 (OdM1; Frogs, amphibians, animals)"	A6MBP6	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	Function: Odorranain-M1 exhibites antimicrobial activities against all of the tested microbes including Gram-positive and Gram-negative bacteria and fungi.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=9.37 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=4.68 ¦Ìg/ml), Bacillus subtilis (MIC=75 ¦Ìg/ml).##Yeast: Candida albicans (MIC=18.75 ¦Ìg/ml). "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP02841	RQKDKRPYSERKNQYTGPQFLYPPERIPPQKVIK	34	Lumbricin I(6¨C34)	O96447	Not found	Not found	Synthetic construct (derived from residues 6¨C34 of lumbricin I)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Lumbricin I(6-34) has marginally stronger antimicrobial activities than lumbricin I. Has weak hemolytic activity  when tested against human erythrocytes.	"[Ref.9784609]Gram-positive bacteria: Bacillus subtilis ATCC 62037 (MIC=8 ?g/ml), Staphylococcus aureus ATCC 15752 (MIC=12 ?g/ml), Streptococcus mutans ATCC 25175 (MIC=20 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 27325 (MIC=8 ?g/ml), Pseudomonas putidaATCC 17426 (MIC=12 ?g/ml), Serratia sp. ATCC 21074 (MIC=12 ?g/ml).##Fungi: Candida albicans ATCC 10231 (MIC=12 ?g/ml), Cryptococcus neoformance ATCC 34881 (MIC=16 ?g/ml), Saccharomyces cerevisiae ATCC 44774 (MIC=8 ?g/ml).##NOTE: Minimal inhibitory concentrations were determined by incubating approximately 104¨C105 CFU/ml of cells with serial dilutions of each peptide in a 96-well microtiter plate.."	"[Ref.9784609]0.03% hemolytic activity at 5 ¦Ìg/ml, 0.07% hemolytic activity at 10 ¦Ìg/ml, 0.13% hemolytic activity at 25 ¦Ìg/ml, 0.17% hemolytic activity at 50 ¦Ìg/ml, 0.21% hemolytic activity at 100 ¦Ìg/ml against human erythrocytes"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9784609	Biochim Biophys Acta. 1998 Oct 22;1408(1):67-76.	"Cho JH, Park CB, Yoon YG, Kim SC."	"Lumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization."
DRAMP02854	GGLRSLGRKILRAWKKYGPIIVPIIRIG	28	Cathelicidin-5 (Antibacterial peptide BMAP-28; Myeloid antib	"P54229, A5PJ96, B9UKL6"	Belongs to the cathelicidin family	CATHL5	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi.
PTM: Contains two disulfide bonds. (By similarity)"	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2 ?M), E. coli ML35 (MIC=2 ?M), E. coli D21 (MIC=0.5 ?M), Salmonella typhimurium ATCC 14028 (MIC=1 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=1 ?M), Serratia marcescens ATCC 8100 (MIC=2 ?M);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2 ?M), Staphylococcus aureus Cowan 1 (MIC=1 ?M), Staphylococcus aureus (MRSA) (MIC=4 ?M), Staphylococcus epidermidis ATCC 12228 (MIC=1 ?M), Bacillus megaterium Bm11 (MIC=2 ?M).##Fungi: Candida albicans (MIC=8 ?M), Cryptococcus neoformans (MIC=4 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8910461##8706679	J Biol Chem. 1996 Nov 8;271(45):28375-28381.##Eur J Biochem. 1996 Jun 15;238(3):769-776.	"Skerlavaj B, Gennaro R, Bagella L, Merluzzi L, Risso A, Zanetti M.##Storici P, Tossi A, Lenarcic B, Romeo D."	"Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities.##Purification and structural characterization of bovine cathelicidins, precursors of antimicrobial peptides."
DRAMP02855	GRFKRFRKKFKKLFKKLSPVIPLLHLG	27	"Cathelicidin-6 (Antibacterial peptide BMAP-27, Myeloid antib"	"P54228, B9UKM5"	Belongs to the cathelicidin family	CATHL6	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix (2 helices; 19 residues)	Not found	2KET resolved by NMR.	"Function: Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi.
PTM: Contains two disulfide bonds. (By similarity)"	"Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=1 ?g/ml), E. coli ML35 (MIC=1 ?g/ml), E. coli D21 (MIC=0.25 ?g/ml), Salmonella typhimurium ATCC 14028 (MIC=1 ?g/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=1 ?g/ml), Serratia marcescens ATCC 8100 (MIC=2 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2 ?g/ml), Staphylococcus aureus Cowan 1 (MIC=2 ?g/ml), Staphylococcus aureus (MRSA) (MIC=4 ?g/ml), S. epidermidis ATCC 12228 (MIC=1 ?g/ml), Bacillus megaterium Bm11 (MIC=2 ?g/ml).##Fungi: Candida albicans (MIC=8 ?g/ml), Cryptococcus neoformans (MIC=4 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8910461##19136450##PubMed ID is not available	J. Biol. Chem. 1996;271:28375-28381.##J. Hered. 2009;100:241-245.##To be Published	"Skerlavaj B, Gennaro R, Bagella L, Merluzzi L, Risso A, Zanetti M.##Gillenwaters EN, Seabury CM, Elliott JS, Womack JE.##Yang S, Jung H, Kim J."	Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities.##Sequence analysis and polymorphism discovery in 4 members of the bovine cathelicidin gene family.##solution structure of BMAP-27.
DRAMP02872	GRFKRFRKKFKKLFKKLS	18	"Myeloid antimicrobial peptide BMAP-27 (1-18) (mammals, animals)"	No entry found	Not found	Not found	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Also has antifungal activity.	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2 ?M), Escherichia coli ML35 (MIC=4 ?M), Escherichia coli D21 (MIC=4 ?M), Salmonella typhimurium ATCC 14028 (MIC=4 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=1 ?M), Serratia marcescens ATCC 8100 (MIC=2 ?M);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2 ?M), Staphylococcus aureus Cowan 1 (MIC=2 ?M), Staphylococcus aureus (MRSA) (MIC=4 ?M), Staphylococcus epidermidis ATCC 12228 (MIC=1 ?M), Bacillus megaterium Bm11 (MIC=2 ?M).##Fungi: Candida albicans (MIC=16 ?M), Cryptococcus neoformans (MIC=4 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8910461	J Biol Chem. 1996 Nov 8;271(45):28375-28381.	"Skerlavaj B, Gennaro R, Bagella L, Merluzzi L, Risso A, Zanetti M."	Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities.
DRAMP02873	GGLRSLGRKILRAWKKYG	18	"Myeloid antimicrobial peptide BMAP-28 (1-18) (mammals, animals)"	No entry found	Not found	Not found	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Also has antifungal activity.	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=1 ?M), Escherichia coli ML35 (MIC=0.5 ?M), Escherichia coli D21 (MIC=0.5 ?M), Salmonella typhimurium ATCC14028 (MIC=2 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=1 ?M), Serratia marcescens ATCC 8100 (MIC=2 ?M);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2 ?M), Staphylococcus aureus Cowan 1 (MIC=1 ?M), Staphylococcus aureus (MIC=4 ?M), Staphylococcus epidermidis ATCC 12228 (MIC=1 ?M), Bacillus megaterium Bm11 (MIC=2 ?M).##Fungi: Candida albicans (MIC=16 ?M), Cryptococcus neoformans (MIC=2 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8910461	J Biol Chem. 1996 Nov 8;271(45):28375-28381.	"Skerlavaj B, Gennaro R, Bagella L, Merluzzi L, Risso A, Zanetti M."	Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities.
DRAMP02875	LPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSKECFETLRGDERILSILRHQNLLKELQDLALQGAKERTHQQ	76	"Vasostatin-1 (VS-1; N-terminal fragment of Chromogranin-A; mammals, animals)"	"P05059, P79392, Q2KJ52"	Belongs to the chromogranin/secretogranin protein family	CHGA	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: Vasostatin-1 has antibacterial activity against Gram-positive bacteria M. luteus, B. megaterium. Possesses antifungal activity against N. crassa, A. fumigatus, A. brassicicola, N. hematococca, F. culmorum and F. oxyporum and against the yeast S. cerevisiae and C. albicans.
Miscellaneous: Binds calcium with a low-affinity."	"Gram-positive bacteria: Micrococcus luteus (MIC=2 ?M), Bacillus megaterium (MIC=0.2 ?M).##Fungi: Neurospora crassa (MIC=3 ?M), Aspergillus fumigatus (MIC=5 ?M), Alternaria brassicicola (MIC=3 ?M), Nectria haematococca (MIC=1 ?M), Fusarium culmorum (MIC=1 ?M), F. oxyporum (MIC=10 ?M), Saccharomyces cerevisiae (MIC=10 ?M), Candida albicans (MIC=10 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Binds calcium with a low-affinity.	10753865	J Biol Chem. 2000 Apr 14;275(15):10745-10753.	"Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, Aunis D, Metz-Boutigue MH."	"Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A."
DRAMP02878	NPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCRKK	38	"Tracheal antimicrobial peptide (TAP; mammals, animals)"	"P25068, O97532"	Belongs to the beta-defensin family (LAP/TAP subfamily)	Not found	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antibacterial activity in vitro. In addition, the peptide is active against Candida albicans, indicating a broad spectrum of activity.
Tissue specificity: Tracheal epithelium.
PTM: Contains three disulfide bonds 5-34; 12-27; 17-35. (By similarity)"	"Gram-negative bacteria: Escherichia coli D31 (MIC=12-25 ?g/ml), Klebsiella pneumoniae 13883 (MIC=12-25 ?g/ml), Pseudomonas aeruginosa 27853 (MIC=25-50 ?g/ml).##Gram-positive bacteria: Staphylococcus aureus 25923 (MIC=25-50 ?g/ml).##Fungi: Candida ablicans (MIC=6-12 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2023943##8506305	Proc Natl Acad Sci U S A. 1991 May 1;88(9):3952-3956.##Proc Natl Acad Sci U S A. 1993 May 15;90(10):4596-4600. 	"Diamond G, Zasloff M, Eck H, Brasseur M, Maloy WL, Bevins CL.##Diamond G, Jones DE, Bevins CL."	"Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA.##Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene."
DRAMP02912	RGLRRLGRKIAHGVKKYGPTVLRIIRIAG	29	"SMAP-29 (Cathelin-related peptide SC5; Myeloid antibacterial peptide MAP-29; mammals, animals)"	"P49928, P49929"	Belongs to the cathelicidin family	Not found	Ovis aries (Sheep)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Alpha helix	Not found	1FRY resolved by NMR.	"Function: Broad spectrum bactericidal agent. 
Biophysicochemical properties: Temperature dependence (Thermostable)."	"[Ref.8549789][No NaCl]: Escherichia coli DH5a (MIC=0.1 ?M), Escherichia coli ML-35p (MIC=0.18 ?M), Pseudomonas aeruginosa PAO1 (MIC=0.17 ?M), Pseudomonas aeruginosa MR3007 (MIC=0.34 ?M), Staphylococcus aureus ATCC (MRSA) 33591 (MIC=1.24 ?M), Staphylococcus aureus 93918 (MIC=0.31 ?M).##[100 mM NaCl]: Escherichia coli DH5a (MIC=0.07 ?M), Escherichia coli ML-35p (MIC=0.12 ?M), Pseudomonas aeruginosa PAO1 (MIC=0.08 ?M), Pseudomonas aeruginosa MR3007 (MIC=0.18 ?M), Staphylococcus aureus ATCC (MRSA) 33591 (MIC=0.65 ?M), Staphylococcus aureus 93918 (MIC=0.43 ?M)."	[Ref.8549789]Not found	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Outer membrane protein I (OprI)	8549789##11932493	FEBS Lett. 1995 Dec 27;377(3):519-522.##Protein Eng. 2002 Mar;15(3):225-232.	"Mahoney MM, Lee AY, Brezinski-Caliguri DJ, Huttner KM.##Sawai MV, Waring AJ, Kearney WR, McCray PB Jr, Forsyth WR, Lehrer RI, Tack BF."	Molecular analysis of the sheep cathelin family reveals a novel antimicrobial peptide.##Impact of single-residue mutations on the structure and Function: of ovispirin/novispirin antimicrobial peptides.
DRAMP02922	KCWNLRGSCREKCIKNEKLYIFCTSGKLCCLKPK	34	"Canine beta-defensin (dogs, mammals, animals)"	No entry found	Not found	Not found	Canis lupus familiaris (Dog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against Gram-positive and Gram-negative bacteria.	"Gram-negative bacteria: Escherichia coli 25922 (MIC=20 ?g/ml), Escherichia coli 700336 (MIC=50 ?g/ml);##Gram-positive bacteria: Klebsiella pneumoniae 10031 (MIC=20 ?g/ml), Listeria monocytogenes 19115 (MIC=10 ?g/ml), Staphylococcus aureus 10832 (MIC=100 ?g/ml), N. gonorrhoeae 10150 (MIC=50 ?g/ml).##Fungi: Candida albicans 14053 (MIC=50 ?g/ml), Candida albicans 11006 (MIC=5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15845463	Infect Immun. 2005 May;73(5):2611-2620.	"Sang Y, Ortega MT, Blecha F, Prakash O, Melgarejo T."	Molecular cloning and characterization of three beta-defensins from canine testes.
DRAMP02923	KCWNLRGSCREKCIKNEKLYIFCTSGKLCCLKPKFQPNMLQR	42	"cBD-1 (Canine beta-defensin 1; dogs, mammals, animals)"	No entry found	Not found	Not found	Canis Lupis (Dog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Listeria monocytogenes(MIC=6 m?g/ml), Staphylococcus aureus (MIC=100 m?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=20-25 m?g/ml), Klebsiella pneumoniae (MIC=20 m?g/ml), Neisseria gonorrhoeae (MIC=50 m?g/ml).##Yeast: Candida albicans (MIC=5-50 m?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15845463	Infect Immun. 2005 May;73(5):2611-2620.	"Sang Y, Ortega MT, Blecha F, Prakash O, Melgarejo T."	Molecular cloning and characterization of three beta-defensins from canine testes.
DRAMP02925	RLKELITTGGQKIGEKIRRIGQRIKDFFKNLQPREEKS	38	"Cathelicidin (dogs, mammals, animals)"	No entry found	Not found	Not found	Canis lupus familiaris (Dog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli (MIC=1.25 ?M), Klebsiella pneumoniae (MIC=1.25 ?M), Salmonella serotype Typhimurium (MIC=1.25 ?M), Pseudomonas aeruginosa (MIC=1.25 ?M), Proteus mirabilis (MIC=1.25 ?M), Salmonella serotype Enteritidis (MIC=0.5 ?M), Neisseria gonorrhoeae (MIC=0.06 ?M).##Gram-positive bacteria: Listeria monocytogenes (MIC=0.5 ?M), Staphylococcus aureus (MIC=50 ?M).##Fungi: Candida albicans (MIC=12.5-50 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17462733	Dev Comp Immunol. 2007;31(12):1278-1296.	"Sang Y, Teresa Ortega M, Rune K, Xiau W, Zhang G, Soulages JL, Lushington GH, Fang J, Williams TD, Blecha F, Melgarejo T."	"Canine cathelicidin (K9CATH): gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide."
DRAMP02933	RRWCFRVCYRGFCYRKCR	18	"Polyphemusin-1 (PM1; crabs, Arthropods, animals)"	P14215	Belongs to the tachyplesin/polyphemusin family	Not found	Limulus polyphemus (Atlantic horseshoe crab)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Beta strand (2 strands; 4 residues)	"The solution structure of polyphemusin I is determined using (1)H-NMR spectroscopy. Polyphemusin I is found to be an amphipathic, beta-hairpin connected by a type I' beta-turn."	1RKK resolved by NMR.	"Function: PM1 showes high antimicrobial activity against the Gram-negative, Gram-positive and fungal specimens tested.
Tissue specificity: Hemocytes.
PTM: Contains two disulfide bonds 4-17; 8-13 and C-terminal amidation."	"Gram-negative bacteria: Escherichia coli UB1005 (MIC=0.5 ?g/ml), E. coli DC2 (MIC=1 ?g/ml), Salmonella typhimurium (defensin-sensitive) (MIC=0.25 ?g/ml), S. typhimurium (MIC=1 ?g/ml), Pseudomonas aeruginosa K799 (MIC=2 ?g/ml), P. aeruginosa Z61 (MIC=1 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus SAP0017 (MIC=2 ?g/ml), Staphylococcus epidermidis (MIC=1 ?g/ml), Enterococcus faecalis (MIC=1 ?g/ml).##Yeasy: Candida albicans (MIC=4 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Amidation	"Disulfide bond between Cys4 and Cys17,Cys8 and Cys13."	L	No cytotoxicity information found	Not found	2514185##15134657	J Biochem. 1989 Oct;106(4):663-668.##Biochim Biophys Acta. 2004 May 6;1698(2):239-250.	"Miyata T, Tokunaga F, Yonega T, Yoshikawa K, Iwanaga S, Niwa M, Takao T, Shimonishi Y.##Powers JP, Rozek A, Hancock RE."	"Antimicrobial peptides, isolated from horseshoe crab hemocytes, tachyplesin II, and polyphemusins I and II: chemical structures and biological activity.##Structure-activity relationships for the beta-hairpin cationic antimicrobial peptide polyphemusin I."
DRAMP02934	RRWSFRVSYRGFSYRKSR	18	PM1-S (linear derivative of PM1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	No secondary structure (CD)	"The CD spectra of PM1-S indicates that, in all environments (phosphate buffer, TFE, and liposomes), the peptide displays no observable patterns that could be related to structural features. This indicates that PM1-S is a flexible molecule with no favoured conformation."	None	Function: PM1-S remaines active against Gram-negative bacteria but displayed poor activity to both Gram-positive and fungal microorganisms.	"Gram-negative bacteria: Escherichia coli UB1005 (MIC=4 ?g/ml), E. coli DC2 (MIC=4 ?g/ml), Salmonella typhimurium (defensin-sensitive) (MIC=2 ?g/ml), S. typhimurium (MIC=8 ?g/ml), Pseudomonas aeruginosa K799 (MIC=32 ?g/ml), P. aeruginosa Z61 (MIC=16 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus SAP0017 (MIC=32 ?g/ml), Staphylococcus epidermidis (MIC=16 ?g/ml), Enterococcus faecalis (MIC=2 ?g/ml).##Yeasy: Candida albicans (MIC=64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15134657	Biochim Biophys Acta. 2004 May 6;1698(2):239-250.	"Powers JP, Rozek A, Hancock RE."	Structure-activity relationships for the beta-hairpin cationic antimicrobial peptide polyphemusin I.
DRAMP02951	MARVSLLLIVLSIALVAPSQGFLKDLLFGEAKTALLEDGTTEILDHVCNFRVMPRLRSWELYFRGDVWCPGWTVIKGESL	80	"PtALF6 (Portunus trituberculatus anti-lipopolysaccharide factor isoform 6; crabs, Arthropods, ani"	No entry found	Not found	Not found	Portunus trituberculatus (Swimming Crab)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Contains a signal peptide and an LPS-binding Domain: (CNFPVMPRLRSWELYFRGDVWC) and two conserved cysteine residues which can form a disulfide bridge.	"Gram-negative bacteria: Vibrio alginolyticus L59 (MIC=1.17-2.33 ?M), Pseudomonas aeruginosa P25 (MIC=9.32-18.64 ?M);##Gram-positive bacteria: Micrococcus luteus M2 (MIC=9.32-18.64 ?M), Staphylococcus aureus S7 (MIC=9.32-18.64 ?M).##Fungi: Pichia pastoris GS115 (MIC>74.57 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipopolysaccharide (LPS)-binding	21362485##23257203	Fish Shellfish Immunol. 2011 Jul;31(1):29-42.##Fish Shellfish Immunol. 2013 Feb;34(2):463-470.	"Liu Y, Cui Z, Song C, Wang S, Li Q.##Liu Y, Cui Z, Li X, Song C, Shi G."	Multiple isoforms of immune-related genes from hemocytes and eyestalk cDNA libraries of swimming crab Portunus trituberculatus.##A newly identified anti-lipopolysaccharide factor from the swimming crab Portunus trituberculatus with broad spectrum antimicrobial activity.
DRAMP02956	SHQDCYEALHKCMASHSKPFSCSMKFHMCLQQQ	33	Dolabellanin B2	P83376	Not found	Not found	Dolabella auricularia (Sea hare)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antibacterial activity against Gram-negative bacteria and Gram-positive bacteria. Also possesses antifungal activity.
PTM: Contains two disulfide bonds. Up to two of the methionines may be oxidized to methionine sulfoxides."	"Gram-positive bacteria: Bacillus subtilis RIMD0225014 (MIC=2.5 ?g/ml), Staphylococcus aureus IID1677 (MRSA) (MIC=20.0 ?g/ml), Listeria monocytogenes VIU206 (MIC=40.0 ?g/ml).##Gram-negative bacteria: Haemophilus influenzae IID983 (MIC=5.0 ?g/ml), V. vulnificus RIMD2219009 (MIC=5.0 ?g/ml), Escherichia coli JM109 (MIC=20.0 ?g/ml), E. coli DH5?¡À (MIC=40.0 ?g/ml).##Fungi: Candida albicans ATCC36232, Candida tropicalis TIMM0313, S. pombe IFO1628, Saccharomyces cerevisiae A581A."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Contains two disulfide bonds. Up to two of the methionines may be oxidized to methionine sulfoxides.	L	No cytotoxicity information found	Not found	12590964	Dev. Comp. Immunol. 2003;27:305-311.	"Iijima R, Kisugi J, Yamazaki M."	A novel antimicrobial peptide from the sea hare Dolabella auricularia.
DRAMP02228	SMLSVLKNLGKVGLGFVACKINKQC	25	"RANATUERIN 1 (Frogs, amphibians, animals)"	P82741 	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans. Has no detectable hemolytic activity.	[Ref.9784389] Gram-positive bacterium: Staphylococcus aureus (MIC=50 ?M);##Gram-negative bacterium: Escherichia coli (MIC=2 ?M);##Yeast: Candida albicans (MIC=70 ?M).	[Ref.9784389] It has no detectable hemolytic activity at aconcentration of 20?g/ml against human red blood cell.	Cyclic	Free	Cyclization (Cys19 and Cys25)	Disulfide bond between Cys19 and Cys25.	L	No cytotoxicity information found	Not found	9784389	Biochem Biophys Res Commun. 1998 Sep 29;250(3):589-592.	"Goraya J, Knoop FC, Conlon JM."	"Ranatuerins: antimicrobial peptides isolated from the skin of the American bullfrog, Rana catesbeiana."
DRAMP02963	GRFRRLRKKTRKRLKKIGKV	20	PMAP-36(1-20)	No entry found	Not found	Not found	Sus scrofa (Pig)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Exerts antimicrobial activity against both Gram-positive and negative bacteria. 	"Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=6 ?M), Bacillus megaterium Bm11 (MIC=3 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=12 ?M), E. coli ML35 (MIC=12 ?M), S. enterica ser. Typhimurium ATCC 14028 (MIC=48 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=3 ?M).##Fungi: Candida albicans c.i. (MIC>64 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16128809	FEBS J. 2005 Sep;272(17):4398-4406.	"Scocchi M, Zelezetsky I, Benincasa M, Gennaro R, Mazzoli A, Tossi A."	Structural aspects and biological properties of the cathelicidin PMAP-36.
DRAMP02964	GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLG	34	PMAP-36(1-34)	No entry found	Not found	Not found	Sus scrofa (Pig)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Exerts antimicrobial activity against both Gram-positive and negative bacteria. 	"Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=1 ?M), S. aureus 710A (MIC=2 ?M), S. aureus SA-62 (MRSA) (MIC=4 ?M), Bacillus megaterium Bm11 (MIC=1 ?M), S. epidermidis ATCC 12228 (MIC=1 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=1 ?M), E. coli ML35 (MIC=1 ?M), E. coli D21 (MIC=1 ?M), E. coli D22 (MIC=0.5 ?M), S. enterica ser. Typhimurium ATCC 14028 (MIC=1 ?M), S. enterica ser. Enteritidis H2 (MIC=1 ?M), P. aeruginosa ATCC 27853 (MIC=1 ?M), S. marcescens ATCC 8100 (MIC=2 ?M).##Fungi: Candida albicans c.i. (MIC=8 ?M), Cryptococcus neoformans c.i.(MIC=2 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16128809	FEBS J. 2005 Sep;272(17):4398-4406.	"Scocchi M, Zelezetsky I, Benincasa M, Gennaro R, Mazzoli A, Tossi A."	Structural aspects and biological properties of the cathelicidin PMAP-36.
DRAMP02965	GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLGC	35	PMAP-36(1-35)2	No entry found	Not found	Not found	Sus scrofa (Pig)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Exerts antimicrobial activity against both Gram-positive and negative bacteria. 	"Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2 ?M), S. aureus 710A (MIC=2 ?M), S. aureus SA-62 (MRSA) (MIC=4 ?M), Bacillus megaterium Bm11 (MIC=1 ?M), S. epidermidis ATCC 12228 (MIC=1 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=1 ?M), E. coli ML35 (MIC=0.5 ?M), E. coli D21 (MIC=0.5 ?M), E. coli D22 (MIC=0.5 ?M), S. enterica ser. Typhimurium ATCC 14028 (MIC=1 ?M), S. enterica ser. Enteritidis H2 (MIC=0.5 ?M), P. aeruginosa ATCC 27853 (MIC=1 ?M), S. marcescens ATCC 8100 (MIC=2 ?M).##Fungi: Candida albicans c.i. (MIC=16 ?M), Cryptococcus neoformans c.i.(MIC=2 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16128809	FEBS J. 2005 Sep;272(17):4398-4406.	"Scocchi M, Zelezetsky I, Benincasa M, Gennaro R, Mazzoli A, Tossi A."	Structural aspects and biological properties of the cathelicidin PMAP-36.
DRAMP02975	VRRFPWWWPFLRR	13	"Tritrpticin (Trp-rich; pigs, mammals, animals)"	No entry found	Belongs to the cathelicidin family	Not found	Sus scrofa (Pig)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix (1 helices; 3 residues)	Not found	1D6X resolved by NMR.	Function: Tritrpticin has strong antimicrobial activity with a wide spectrum.	"Gram-negative bacteria: Escherichia coli (5 mm), Pseudomonas aeruginosa (3 mm), Klebsiella pneumonia (7 mm), Proteus mirabilis (1 mm);##Gram-positive bacteria: Staphylococcus epidermidis (5 mm), Streptococcus group D (4 mm). [inhibit zones in mm]##Fungi: Aspergillus fumigatus (MIC=250 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8706838##10606506	FEBS Lett. 1996 Jul 15;390(1):95-98.##Biochemistry. 1999 Dec 21;38(51):16749-55.	"Lawyer C, Pai S, Watabe M, Borgia P, Mashimo T, Eagleton L, Watabe K.Schibli DJ, Hwang PM, Vogel HJ.##Schibli DJ, Hwang PM, Vogel HJ."	Antimicrobial activity of a 13 amino acid tryptophan-rich peptide derived from a putative porcine precursor protein of a novel family of antibacterial peptides.##Structure of the antimicrobial peptide tritrpticin bound to micelles: a distinct membrane-bound peptide fold.
DRAMP02980	GLICESCRKIIQKLEDMVGPQPNEDTVTQAASRVCDKMKILRGVCKKIMRTFLRRISKDILTGKKPQAICVDIKICKE	78	"Antimicrobial peptide NK-lysin (NKL; pigs, mammals, animals)"	Q29075	Not found	NKL	Sus scrofa (Pig)	"Antimicrobial, Antibacterial, Antifungal, Antitumor"	Protein level	Alpha helix 	Not found	1NKL resolved by NMR.	"Function: May be an effector molecule of cytotoxic activity. High activity against E. coli and B. megaterium, moderate against A. calcoaceticus and S. pyogenes. Has some antifungal activity against Candida albicans.
Tissue specificity: Cytotoxic T and NK cells. Induction: By interleukin-2.
PTM: Contains three disulfide bonds 4-76; 7-70; 35-45."	"[with medium E]: Escherichia coli D21 (MIC=0.5 ?M), Escherichia coli Bd2221/75 (MIC=10 ?M), Acinetobacter calcoaceticus Ac 11 (MIC=7 ?M), Bacillus megaterium Bmll (MIC=1.6 ?M);##[without medium E]: Escherichia coli D21 (MIC=8 ?M), Escherichia coli Bd2221/75 (MIC=39 ?M), Bacillus megaterium Bmll (MIC=0.8 ?M), Streptococcus pyogenes w.t. (MIC=34 ?M), Candida albicans w.t. (MIC=31 ?M)."	[Ref.7737114] It exhibits no hemolytic activity at 170 ?M against sheep red blood cells.	Cyclic	Free	Free	Disulfide bonds between Cys4 and Cys76; Cys7 and Cys70; Cys35 and Cys45.	L	"[Ref.7737114] NK-lysin at 50¦Ìg/ml was able to give 90% lysis of 5'Cr-labelled YAC-1 cells in a medium with 2% fetal calf serum(FCS) and 75% lysis in phosphate-buffered saline(PBS), 15% lysis suspended in medium E."	Lipopolysaccharide (LPS)-binding	7737114##9334742	EMBO J. 1995 Apr 18;14(8):1615-1625.##Nat Struct Biol. 1997 Oct;4(10):793-795.	"Andersson M, Gunne H, Agerberth B, Boman A, Bergman T, Sillard R, J?rnvall H, Mutt V, Olsson B, Wigzell H, et al.##Liepinsh E, Andersson M, Ruysschaert JM, Otting G."	"NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity.##Saposin fold revealed by the NMR structure of NK-lysin."
DRAMP01377	FMPILSCSRFKRC	13	"Odorranain-G1 (OdG1; Frogs, amphibians, animals)"	"A6MBL7, A6MBL8"	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Odorranain-G1 adopts 44.1% ¦Â-sheet structure in water solution.	None	Function: Odorranain-G1 exhibites antimicrobial activities against all of the tested microbes including Gram-positive and Gram-negative bacteria and fungi. Has no hemolytic activity against red cell.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=4.68 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=9.37 ¦Ìg/ml), Bacillus subtilis (MIC=37.5 ¦Ìg/ml).##Yeast: Candida albicans (MIC=1.10 ¦Ìg/ml)."	[Ref:17272268] It has no hemolytic activity against rabbit red blood cells	Cyclic	Free	Cyclization (Cys7 and Cys13)	Disulfide bond between Cys7 and Cys13.	L	No cytotoxicity information found	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP02999	PFKISIHL	8	"Jellein-1 (Jelleine-I; chain of Major royal jelly protein 1; Insects, animals)"	"O18330, Q548D6"	Belongs to the major royal jelly protein family	MRJP1	Apis mellifera (Honeybee)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Jellein-1 has antibacterial and antifungal activity.
Tissue specificity: Found in the hypopharyngeal glands of the worker honeybee.
Developmental stage: Produced in the cephalic glands of both the nurse bee and the forager bee. This bee milk protein changes to alpha-glucosidase in accordance with the age-dependent role change of the worker bee.
Miscellaneous: Exhibits a growth factor-like action on primary-cultured rat hepatocytes by stimulating DNA synthesis and protecting cells from apoptosis induced by serum deprivation. Also activates mitogen-activated protein kinase, as well as protein kinase B, a key regulator of cell survival. Degraded proportionally to the period of storage, and is completely lost during storage at 40 degrees Celsius for 30 days. PTM: Histidine amide at H7."	"Gram-positive bacteria: Staphylococcus aureus ATCC 6535 (MIC=10 ?g/ml), S. saprophyticus (MIC=15 ?g/ml), Bacillus subtilis CCT 2471 (MIC=10 ?g/ml).##Gram-negative bacteria: Escherichia coli CCT 1371 (MIC=2.5 ?g/ml), Enterobacter cloacae ACCT 23355 (MIC=10 ?g/ml), Klebsiella pneumoniae ACCT 13883 (MIC=10 ?g/ml), Pseudomonas aeruginosa ACCT 27853 (MIC=10 ?g/ml).##Yeast: Candida albicans (MIC=2.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15203237##9395329##21516106	Peptides. 2004 Jun;25(6):919-928.##Eur J Biochem. 1997 Nov 1;249(3):797-802.##Nature. 2011 May 26;473(7348):478-483.	"Fontana R, Mendes MA, de Souza BM, Konno K, C¨¦sar LM, Malaspina O, Palma MS.##Ohashi K, Natori S, Kubo T.##Kamakura M."	Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera).##Change in the mode of gene expression of the hypopharyngeal gland cells with an age-dependent role change of the worker honeybee Apis mellifera L.##Royalactin induces queen differentiation in honeybees.
DRAMP03000	TPFKISIHL	9	"Jellein-2 (Jelleine-II; chain of Major royal jelly protein 1; Insects, animals)"	"O18330, Q548D6"	Belongs to the major royal jelly protein family	MRJP1	Apis mellifera (Honeybee)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Jellein-2 has antibacterial and antifungal activity. Jellein-2 is probably processed to yield jellein-1 and jellein-4.
Tissue specificity: Found in the hypopharyngeal glands of the worker honeybee.
Developmental stage: Produced in the cephalic glands of both the nurse bee and the forager bee. This bee milk protein changes to alpha-glucosidase in accordance with the age-dependent role change of the worker bee.
Miscellaneous: Exhibits a growth factor-like action on primary-cultured rat hepatocytes by stimulating DNA synthesis and protecting cells from apoptosis induced by serum deprivation. Also activates mitogen-activated protein kinase, as well as protein kinase B, a key regulator of cell survival. Degraded proportionally to the period of storage, and is completely lost during storage at 40 degrees Celsius for 30 days. PTM: Leucine amide at L9."	"Gram-positive bacteria: Staphylococcus aureus ATCC 6535 (MIC=15 ?g/ml), S. saprophyticus (MIC=10 ?g/ml), Bacillus subtilis CCT 2471 (MIC=30 ?g/ml);##Gram-negative bacteria: Escherichia coli CCT 1371 (MIC=15 ?g/ml), Enterobacter cloacae ACCT 23355 (MIC=15 ?g/ml), Klebsiella pneumoniae ACCT 13883 (MIC=15 ?g/ml), Pseudomonas aeruginosa ACCT 27853 (MIC=15 ?g/ml).##Yeast: Candida albicans (MIC=2.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15203237##9395329##21516106	Peptides. 2004 Jun;25(6):919-928.##Eur J Biochem. 1997 Nov 1;249(3):797-802.##Nature. 2011 May 26;473(7348):478-483.	"Fontana R, Mendes MA, de Souza BM, Konno K, C¨¦sar LM, Malaspina O, Palma MS.##Ohashi K, Natori S, Kubo T.##Kamakura M."	Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera).##Change in the mode of gene expression of the hypopharyngeal gland cells with an age-dependent role change of the worker honeybee Apis mellifera L.##Royalactin induces queen differentiation in honeybees.
DRAMP03001	EPFKISIHL	9	"Jellein-3 (Jelleine-III; Insects, animals)"	P84759	Not found	MRJP1	Apis mellifera (Honeybee)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Jellein-3 has antibacterial and antifungal activity.
Tissue specificity: Found in the hypopharyngeal glands of the worker honeybee.
PTM: Leucine amide at L9."	"Gram-positive bacteria: Staphylococcus aureus ATCC 6535 (MIC=30 ?g/ml), S. saprophyticus (MIC=30 ?g/ml);##Gram-negative bacteria: Escherichia coli CCT1371 (MIC=15 ?g/ml), Enterobacter cloacae ATCC 23355, Klebsiella pneumoniae ATCC 13883, Pseudomonas aeruginosa ATCC 27853 (MIC=30 ?g/ml).##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15203237	Peptides. 2004 Jun;25(6):919-928.	"ntana R, Mendes MA, de Souza BM, Konno K, C¨¦sar LM, Malaspina O, Palma MS."	Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera).
DRAMP03057	GSKKPVPIIYCNRRTGKCQRM	21	"Thanatin(insects, arthropods, invertebrates, animals)"	P55788 	Not found	Not found	Podisus maculiventris	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Beta strand	"Contain C-terminally a loop of 6 residues, delineated by an intramolecular disulfide bridge. This loop carries a strong positive charge in both molecules and contains a central threonine residue, which separates two subgroups of electropositivity."	8TFV	Function: Insect defense peptide with a broad spectrum of activity against Gram-positive and Gram-negative bacteria and fungi. No activity against S.aureus. Stops respiration in bacteria but does not permeabilize their inner membranes. Has no detectable hemolytic activity. 	"[Ref.8577744] Gram-positive bacteria: Aerococcus viridans (MIC=0.6-1.2 ?M), Micrococcus luteus (MIC=1.2-2.5 ?M), Bacillus megaterium (MIC=2.5-5 ?M), Bacillus subtilis (MIC=2.5-5 ?M), Pediococcus acidilactici (MIC=20-40 ?M);##Gram-negative bacteria: Escherichia coli D22 (MIC=0.3-0.6 ?M), Escherichia coli D31 (MIC=0.3-0.6 ?M), Escherichia coli 1106 (MIC=0.6-1.2 ?M), Salmonella typhimurium (MIC=0.6-1.2 ?M), Klebsiella pneumoniae (MIC=0.6-1.2 ?M), Enterobacter cloacae (MIC=1.2-2.5 ?M), Erwinia carotovora (MIC=10-20 ?M), Pseudomonas aeruginosa (MIC=20-40 ?M);##Fungi: Neurospora crassa (MIC=0.6-1.2 ?M), Botrytis cinerea (MIC=1.2-2.5 ?M), Nectria haematococca (MIC=1.2-2.5 ?M), Trichoderma viride (MIC=1.2-2.5 ?M), Alternaria brassicicola (MIC=2.5-5 ?M), Fusarium culmorum (MIC=2.5-5 ?M), Ascochyta pisi (MIC=5-10?M), Fusarium oxysporum (MIC=10-20 ?M)."	[Ref.8577744] It exhibits no hemolytic activity at 40 ?M against porcine erythrocytes.	Cyclic	Free	Free	Disulfide bond between Cys11 and Cys18.	L	No cytotoxicity information found	Not found	8577744##9760181	Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-1225.##Eur J Biochem. 1998 Sep 1;256(2):404-410.	"Fehlbaum P, Bulet P, Chernysh S, Briand JP, Roussel JP, Letellier L, Hetru C, Hoffmann JA.##Mandard N, Sodano P, Labbe H, Bonmatin JM, Bulet P, Hetru C, Ptak M, Vovelle F."	"Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides.##Solution structure of thanatin, a potent bactericidal and fungicidal insect peptide, determined from proton two-dimensional nuclear magnetic resonance data."
DRAMP03007	GFLSALKKYLPIVLKHV	17	"Osmin (Insects, animals)"	P0CD70	Not found	Not found	Osmia rufa (Red mason bee)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix (CD)	"In absence of TFE, the spectrum shows a random coil type structure. When increasing the concentration of TFE from 0 to 20%, a transition into an ¦Á-helix structure is observed."	None	"Function: Synthetic peptide exhibits hemolytic activity to human erythrocytes and inhibits bacterial and fungal growth at micromolar concentrations. A synthetic peptide with a free C-terminus shows weaker hemolytic (5.0 HU/mg), antibacterial and antifungal activities.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation."	[Ref.19109988]Gram-positive bacterium: Micrococcus luteus (MIC=1.56-0.78 ?M);##Gram-negative bacterium: Escherichia coli SBS363 (MIC=3.125-1.56 ?M);##fungi: Fusarium oxysporum (MIC=0.78-0.39 ?M).	[Ref.19109988]5.0 HU/mg hemolytic activity against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19109988	Toxicon. 2010 Jan;55(1):20-27.	"?cklin R, Favreau P, Thai R, Pflugfelder J, Bulet P, Mebs D."	Structural identification by mass spectrometry of a novel antimicrobial peptide from the venom of the solitary bee Osmia rufa (hymenoptera: megachilidae).
DRAMP03033	INWKGIAAMAKKLL	14	"Mastoparan-like peptide 12a (Insects, animals)"	P0C1M4	Not found	Not found	Vespa magnifica (Hornet)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Mast cell degranulating peptide. Has little hemolytic activity.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation (Leucine amide: L14). "	[Ref.17046111]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=7.5 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=3.7 ?g/ml);##Fungi: Candida albicans ATCC 2002 (MIC=3.7 ?g/ml).	[Ref.16330062]Little hemolytic activity at 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16330062##17046111	Toxicon. 2006 Feb;47(2):249-253.##Peptides. 2006 Dec;27(12):3053-3057.	"Xu X, Li J, Lu Q, Yang H, Zhang Y, Lai R.##Xu X, Yang H, Yu H, Li J, Lai R."	Two families of antimicrobial peptides from wasp (Vespa magnifica) venom.##The mastoparanogen from wasp.
DRAMP03034	INWKGIAAMKKLL	13	"Mastoparan-like peptide 12b (Insects, animals)"	P0C1M5	Not found	Not found	Vespa magnifica (Hornet)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Mast cell degranulating peptide. Has little hemolytic activity. Shows antimicrobial activity.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation (Leucine amide: L13)."	[Ref.16330062]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=15 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=3.7 ?g/ml);##Fungi: Candida albicans ATCC 2002 (MIC=7.5 ?g/ml).	[Ref.16330062]Little hemolytic activity at 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16330062	Toxicon. 2006 Feb;47(2):249-53. Epub 2005 Dec 5. Peptides. 2006 Dec;27(12):3053-7. Epub 2006 Oct 13.	"Xu X, Li J, Lu Q, Yang H, Zhang Y, Lai R.Xu X, Yang H, Yu H, Li J, Lai R."	Two families of antimicrobial peptides from wasp (Vespa magnifica) venomThe mastoparanogen from wasp.
DRAMP03035	INLKAIAALAKKLLG	15	"Mastoparan-like peptide 12c (Insects, animals)"	A0SPI0	Not found	Not found	Vespa magnifica (Hornet)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Shows mast cell degranulation and antimicrobial activities.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation (Leucine amide: L14). "	Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.0 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=3.0 ?g/ml).##Fungi: Candida albicans ATCC 2002 (MIC=12.0 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17046111	Peptides. 2006 Dec;27(12):3053-3057.	"Xu X, Yang H, Yu H, Li J, Lai R."	The mastoparanogen from wasp.
DRAMP03036	INLKAIAAMAKKLL	14	"Mastoparan-like peptide 12d (Insects, animals)"	P0C5G7	Not found	Not found	Vespa magnifica (Hornet)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Shows mast cell degranulation and antimicrobial activities.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation (Leucine amide: L14). "	Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3.0 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=1.5 ?g/ml).##Fungi: Candida albicans ATCC 2002 (MIC=12.0 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17046111	Peptides. 2006 Dec;27(12):3053-3057.	"Xu X, Yang H, Yu H, Li J, Lai R."	The mastoparanogen from wasp.
DRAMP03038	LNLKGLIKKVASLLN	15	"Eumenitin-R (Insects, animals)"	P0CJ36	Not found	Not found	Eumenes rubrofemoratus (Solitary wasp)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Linear cationic alpha-helical peptide that acts as antimicrobial peptide by forming pore in membrane. Has antibacterial activities against both Gram-positive and Gram-negative strains. Has more potent activities against the yeast C.albicans. Shows moderate mast cell degranulation and leishmanicidal activities. Has a very low hemolytic activity against mice erythrocytes.
Tissue specificity: Expressed by the venom sac."	"[Ref.21549739]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=60 ?M), Staphylococcus epidermidis (clinical sample) (MIC=30 ?M), Micrococcus luteus ATCC 10240 (MIC=15 ?M), Streptococcus pyogenes (clinical sample) (MIC=15 ?M), Bacillus subtilis ATCC 6633 (MIC=7.5 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 ?M), Proteus mirabilis (clinical sample) (MIC=60 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=30 ?M), Stenotrophomonas maltophilia ATCC 13637 (MIC=15 ?M);##Fungi: Candida albicans ATCC 90112 (MIC<7.5 ?M)."	[Ref.21549739]EC50=530.3 ¦ÌM against mice erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane (Note: Assumes an amphipathic alpha-helical conformation in a lipid environmen	21549739	Toxicon. 2011 Jun;57(7-8):1081-1092.	"Rangel M, Cabrera MP, Kazuma K, Ando K, Wang X, Kato M, Nihei K, Hirata IY, Cross TJ, Garcia AN, Faquim-Mauro EL, Franzolin MR, Fuchino H, Mori-Yasumoto K, Sekita S, Kadowaki M, Satake M, Konno K."	Chemical and biological characterization of four new linear cationic ?¡À-helical peptides from the venoms of two solitary eumenine wasps.
DRAMP03039	LNLKGLFKKVASLLT	15	"Eumenitin-F (Insects, animals)"	P0CJ37	Not found	Not found	Eumenes fraterculus (Solitary wasp)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Linear cationic alpha-helical peptide that acts as antimicrobial peptide by forming pore in membrane. Has antibacterial activities against both Gram-positive and Gram-negative strains. Has more potent activities against the yeast C.albicans. Shows moderate mast cell degranulation and leishmanicidal activities. Has a very low hemolytic activity against mice erythrocytes.
Tissue specificity: Expressed by the venom sac."	"[Ref.21549739]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC>60 ?M), Staphylococcus epidermidis (clinical sample) (MIC=30 ?M), Micrococcus luteus ATCC 10240 (MIC=30 ?M), Streptococcus pyogenes (clinical sample) (MIC=30 ?M), Bacillus subtilis ATCC 6633 (MIC=30 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 ?M), Proteus mirabilis (clinical sample) (MIC>60 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=30 ?M), Stenotrophomonas maltophilia ATCC 13637 (MIC=15 ?M);##Fungi: Candida albicans ATCC 90112 (MIC=7.5 ?M)."	[Ref.21549739]EC50=353.4 ¦ÌM against mice erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane (Note: Assumes an amphipathic alpha-helical conformation in a lipid environmen	21549739	Toxicon. 2011 Jun;57(7-8):1081-1092.	"Rangel M, Cabrera MP, Kazuma K, Ando K, Wang X, Kato M, Nihei K, Hirata IY, Cross TJ, Garcia AN, Faquim-Mauro EL, Franzolin MR, Fuchino H, Mori-Yasumoto K, Sekita S, Kadowaki M, Satake M, Konno K."	Chemical and biological characterization of four new linear cationic ?¡À-helical peptides from the venoms of two solitary eumenine wasps.
DRAMP03040	FDVMGIIKKIAGAL	14	"Eumenine mastoparan-EF (EMP-EF; Insects, animals)"	P0CJ39	Not found	Not found	Eumenes fraterculus (Solitary wasp)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Linear cationic alpha-helical peptide that acts as antimicrobial peptide by forming pore in membrane. Has antibacterial activities against both Gram-positive and Gram-negative strains. Has more potent activities against the yeast C.albicans. Shows moderate mast cell degranulation and leishmanicidal activities. Has a very low hemolytic activity against mice erythrocytes.
Tissue specificity: Expressed by the venom sac.
PTM: C-terminal amidation (Leucine amide: L14)."	"[Ref.21549739]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=30 ?M), Staphylococcus epidermidis (clinical sample) (MIC=30 ?M), Micrococcus luteus ATCC 10240 (MIC=30 ?M), Streptococcus pyogenes (clinical sample) (MIC>30 ?M), Bacillus subtilis ATCC 6633 (MIC=30 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 ?M), Proteus mirabilis (clinical sample) (MIC=60 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC>30 ?M), Stenotrophomonas maltophilia ATCC 13637 (MIC>30 ?M);##Fungi: Candida albicans ATCC 90112 (MIC=7.5 ?M)."	[Ref.21549739]EC50=181.1 ¦ÌM against mice erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane (Note: Assumes an amphipathic alpha-helical conformation in a lipid environmen	21549739	Toxicon. 2011 Jun;57(7-8):1081-1092.	"Rangel M, Cabrera MP, Kazuma K, Ando K, Wang X, Kato M, Nihei K, Hirata IY, Cross TJ, Garcia AN, Faquim-Mauro EL, Franzolin MR, Fuchino H, Mori-Yasumoto K, Sekita S, Kadowaki M, Satake M, Konno K."	Chemical and biological characterization of four new linear cationic ?¡À-helical peptides from the venoms of two solitary eumenine wasps.
DRAMP03041	FDIMGLIKKVAGAL	14	"Eumenine mastoparan-ER (EMP-ER; Insects, animals)"	P0CJ38	Not found	Not found	Eumenes rubrofemoratus (Solitary wasp)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Linear cationic alpha-helical peptide that acts as antimicrobial peptide by forming pore in membrane. Has antibacterial activities against both Gram-positive and Gram-negative strains. Has more potent activities against the yeast C.albicans. Shows moderate mast cell degranulation and leishmanicidal activities. Has a very low hemolytic activity against mice erythrocytes.
Tissue specificity: Expressed by the venom sac.
PTM: C-terminal amidation (Leucine amide: L14)."	"[Ref.21549739]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=30 ?M), Staphylococcus epidermidis (clinical sample) (MIC=30 ?M), Micrococcus luteus ATCC 10240 (MIC>30 ?M), Streptococcus pyogenes (clinical sample) (MIC>30 ?M), Bacillus subtilis ATCC 6633 (MIC=30 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=30 ?M), Proteus mirabilis (clinical sample) (MIC=60 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC>30 ?M), Stenotrophomonas maltophilia ATCC 13637 (MIC>30 ?M);##Fungi: Candida albicans ATCC 90112 (MIC=7.5 ?M)."	[Ref.21549739]EC50=200 ¦ÌM against mice erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane (Note: Assumes an amphipathic alpha-helical conformation in a lipid environmen	21549739	Toxicon. 2011 Jun;57(7-8):1081-1092.	"Rangel M, Cabrera MP, Kazuma K, Ando K, Wang X, Kato M, Nihei K, Hirata IY, Cross TJ, Garcia AN, Faquim-Mauro EL, Franzolin MR, Fuchino H, Mori-Yasumoto K, Sekita S, Kadowaki M, Satake M, Konno K."	Chemical and biological characterization of four new linear cationic ?¡À-helical peptides from the venoms of two solitary eumenine wasps.
DRAMP03045	VTCELLMFGGVVGDSACAANCLSMGKAGGSCNGGLCDCRKTTFKELWDKRFG	52	"Defensin-NV (Insects, animals)"	No entry found	Not found	Not found	Nasonia vitripennis (Ectoparasitic wasp)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Bridge	Not found	None	"Function: Defensin-NV had little hemolytic activity to rabbit red blood cells and has antimicrobial activity against Gram-positive, Gram-negative bacteria, and Fungi."	"[Ref.20362606]Gram-positive bacteria: Staphylococcus aureus (MIC=0.93 ?M), Bacillus cereus (MIC=0.93 ?M), B. dysenteriae (MIC=0.46 ?M);##Gram-negative bacteria: Escherichia coli (MIC=1.86 ?M), Pseudomonas aeruginosa (MIC=9.3 ?M).##Yeast: Candida albicans (MIC=1.86 ?M)."	[Ref.20362606]5% hemolytic activity at 200 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20362606	Toxicon. 2010 Aug 1;56(1):101-106.	"Ye J, Zhao H, Wang H, Bian J, Zheng R."	A defensin antimicrobial peptide from the venoms of Nasonia vitripennis.
DRAMP03046	ILGIITSLLKSL	12	"Orancis-protonectin (chain of Venom peptide 2-long; Venom peptide 2, OdVP2; Insects, animals)"	"P86147, C7DT08"	Belongs to the MCD family (Protonectin subfamily)	VP2	Orancistrocerus drewseni (Solitary wasp)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Has potent hemolytic activity against ovine erythrocytes at micromolar concentrations. Also exhibits strong antimicrobial activity against fungi. Venom peptide 2-long has substantially lower antimicrobial activity against C. albicans and bacteria than Orancis-protonectin but has equivalent activity against Botrytis cinerea.	"[Ref.19857508]Gram-positive bacteria: Staphylococcus aureus (MIC=25 ¦Ìg/ml);##Fungi: Candida albicans (MIC<100 ?g/ml), Botrytis cinerea (MIC=0.5 ?g/ml)."	[Ref.18695936]84% hemolytic activity at 50 ¦ÌM against sheep blood cells.	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19857508##18695936	Toxicon. 2010 Apr 1;55(4):711-718.##Amino Acids. 2009 Jul;37(2):389-394.	"Baek JH, Lee SH.##Murata K, Shinada T, Ohfune Y, Hisada M, Yasuda A, Naoki H, Nakajima T."	"Isolation and molecular cloning of venom peptides from Orancistrocerus drewseni (Hymenoptera: Eumenidae).##Novel mastoparan and protonectin analogs isolated from a solitary wasp, Orancistrocerus drewseni drewseni."
DRAMP03047	EPILGIITSLLKSL	14	"Venom peptide 2-long (OdVP2L; analog of OdVP2; Insects, animals)"	"P86147, C7DT08"	Belongs to the MCD family (Protonectin subfamily)	VP2	Orancistrocerus drewseni (Solitary wasp)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has potent hemolytic activity against ovine erythrocytes at micromolar concentrations.
Tissue specificity: Expressed by the venom gland."	"[Swiss_Prot Entry P86147]Fungi: Botrytis cinerea (MIC=0.5 ?g/ml), Candida albicans (MIC=100 ?g/ml);##Gram-positive bacterium: S. aureus (MIC=25 ?g/ml);##Gram-negative bacterium: Escherichia coli."	[Swiss_Prot Entry P86147]has potent hemolytic activity against ovine erythrocytes at micromolar concentrations	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19857508##18695936	Toxicon. 2010 Apr 1;55(4):711-718.##Amino Acids. 2009 Jul;37(2):389-394.	"Baek JH, Lee SH.##Murata K, Shinada T, Ohfune Y, Hisada M, Yasuda A, Naoki H, Nakajima T."	"Isolation and molecular cloning of venom peptides from Orancistrocerus drewseni (Hymenoptera: Eumenidae).##Novel mastoparan and protonectin analogs isolated from a solitary wasp, Orancistrocerus drewseni drewseni."
DRAMP03056	SLLSLIRKLIT	11	"Decoralin (Insects, animals)"	P85870	Not found	Not found	Oreumenes decoratus (Potter wasp)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Linear cationic alpha-helical peptide that acts as antimicrobial peptide. At high concentrations exhibits activity in stimulating degranulation from rat peritoneal mast cells. Inhibits the growth of L.major promastigotes in vitro with an IC50 of 72 ?M. Has hemolytic activity towards human and mouse erythrocytes.
Tissue specificity: Expressed by the venom gland."	"[Ref.17981364]Gram-positive bacteria: Staphylococcus aureus CCT 6538 (MIC=40 ?M), S. saprophyticus (MIC=40 ?M), Bacillus subtilis CCT 2471 (MIC=40 ?M), B. thuringiensis (MIC=40 ?M);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=80 ?M), Escherichia coli CCT 1371 (MIC=160 ?M), Klebsiella pneumoniae ATCC 13883 (MIC=80 ?M), A. faecalis ATCC 8750 (MIC=40 ?M);##Fungi: Candida albicans (MIC=40 ?M), L. major promastigotes (IC50=72 ?M)."	[Ref.17981364]EC50=1 mM against mouse erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	17981364	Peptides. 2007 Dec;28(12):2320-2327.	"Konno K, Rangel M, Oliveira JS, Dos Santos Cabrera MP, Fontana R, Hirata IY, Hide I, Nakata Y, Mori K, Kawano M, Fuchino H, Sekita S, Neto JR."	"Decoralin, a novel linear cationic alpha-helical peptide from the venom of the solitary eumenine wasp Oreumenes decoratus."
DRAMP03063	DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCET	44	"Defensin ARD1 (Heliomicin analogs; Insects, animals)"	P84156	Not found	Not found	Archaeoprepona demophon (One-spotted leafwing butterfly)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	Not found	"1OZZ, 1P00, 1P0A resolved by NMR."	"Function: Possesses potent anti-fungal activity.
PTM: Contains three disulfide bonds 7-32; 18-40; 22-42. "	"Fungi: Candida albicans IHEM 8060 (MIC=6.25 ?g/ml), Cryptococcus neoformans A (MIC=12.5 ?g/ml), Aspergillus fumigatus GASP4707 (MIC=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic(CS¦Á¦Â scaffold (an ¦Á-helix linked to a ¦Â-she	Free	Free	Disulfide bonds between Cys7 and Cys32; Cys18 and Cys40; Cys22 and Cys42.	L	No cytotoxicity information found	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03090	GWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATAR	39	"Drosophila cecropin B (CecB; Insects, animals)"	"P14956, O16826, O16827, O16828, O18647, O61274, Q9V425"	Belongs to the cecropin family	CecB	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Induced as part of the humoral response to a bacterial invasion. Transcripts appear within one hour after injection of bacteria into the hemocoel, reach a maximum after 2-6 hours and have almost disappeared after 24 hours. Similar response is seen when flies ingest bacteria present in their food. [Ref.1]"	"Gram-negative bacteria: Escherichia coli D21 (MIC=1.8 ?M), Enterobacter cloacae b12 (MIC=1.0 ?M), Pseudomonas aeruginosa OT97 (MIC=4.2 ?M);##Gram-positive bacteria: Bacillus megatherium Bm11 (MIC=3.7 ?M), Bacillus subtilis Bsll (MIC=3.2 ?M), Micrococcus luteus MI11 (MIC=59 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2390977##2104802	EMBO J. 1990 Sep;9(9):2969-2976.##EMBO J. 1990 Jan;9(1):217-224.	"Samakovlis C, Kimbrell DA, Kylsten P, Engstr?m A, Hultmark D.##Kylsten P, Samakovlis C, Hultmark D."	The immune response in Drosophila: pattern of cecropin expression and biological activity.##The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection.
DRAMP03096	RRQGPIFDTRPSPFNPNQPRPGPIY	25	"Metchnikowin-2 (Insects, animals)"	No entry found	Not found	Not found	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Micrococcus luteus (MIC=0.5-1.0 ?M).##Fungi: Neurospora crassa (MIC=0.5-1.0 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7588819	Eur J Biochem. 1995 Oct 15;233(2):694-700.	"Levashina EA, Ohresser S, Bulet P, Reichhart JM, Hetru C, Hoffmann JA."	"Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties."
DRAMP18495	QCRRLCYKQRCVTYCRGR	18	"Gomesin (Gm; Spiders, arachnids, Chelicerata, arthropods, invertebrates, animals)"	P82358 	Belongs to the tachyplesin family	Not found	Acanthoscurria gomesiana (Tarantula spider) (Phormictopus pheopygus)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiparasitic, Antimalarial, Antic"	Protein level	Beta sheet	Not found	1KFP resolved by NMR.	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi. It shows hemolytic activity.
Tissue specificity: In hemocytes only, but not in all hemocytes observed."	"[Ref.10942757] Gram-positive bacteria: Aerococcus viridans (MIC=0.8-1.6 ¦ÌM), Bacillus cereus (MIC=6.25-12.5 ¦ÌM), Bacillus megaterium (MIC=0.2-0.4 ¦ÌM), Bacillus thuringiensis (MIC=1.6-3.15 ¦ÌM), Enterococcus faecalis (MIC=6.2-12.5 ¦ÌM), Listeria monocytogenes (MIC=0.8-1.6 ¦ÌM), Micrococcus luteus (MIC=0.4-0.8 ¦ÌM), Pediococcus acidolacrici (MIC=3.15-6.25 ¦ÌM), Staphylococcus aureus (MIC=1.6-3.15 ¦ÌM), Staphylococcus epidermidis (MIC=0.8-1.6 ¦ÌM), Staphylococcus haemolyticus (MIC=0.8-1.6 ¦ÌM), Staphylococcus saprophyticus (MIC=0.8-1.6 ¦ÌM), Streptococcus pyogenes (MIC=1.6-3.15 ¦ÌM), Nocardia asteroides (MIC=1.6-3.15 ¦ÌM);##Gram-negative bacteria: Escherichia coli 1106 (MIC=0.8-1.6 ¦ÌM), Escherichia coli D22 (MIC=0.4-0.8 ¦ÌM), Escherichia coli D31 (MIC=0.8-1.6 ¦ÌM), Escherichia coli SBS363 (MIC=0.4-0.8 ¦ÌM), Erwinia carolovora (MIC=3.15-6.25 ¦ÌM), Enterobacter cloacae ¦Â12 (MIC=3.15-6.25 ¦ÌM), Klebsiella pneumoniae (MIC=3.15-6.25 ¦ÌM), Pseudomonas aeruginosa (MIC=1.6-3.15 ¦ÌM), Salmonella thyphinurium (MIC=0.8-1.6 ¦ÌM), Xhantomonas campestris pv. orizae (MIC=3.15-6.25 ¦ÌM);##Fungi: Alternaria brassicola (MIC=0.4-0.8 ¦ÌM), Aspergillus fumigatus (MIC=1.6-3.15 ¦ÌM), Beauveria bassiana (MIC=12.5-25 ¦ÌM), Fusarium culmorum (MIC=0.4-0.8 ¦ÌM), Fusarium oxysporum (MIC=0.4-0.8 ¦ÌM), Neurospora crassa (MIC=0.4-0.8 ¦ÌM), Nectria haematococca (MIC=0.2-0.4 ¦ÌM), Tricoderma viridae (MIC=0.4-0.8 ¦ÌM), Tricophvton mentagrophytes (MIC=0.8-1.6 ¦ÌM);##Yeasts: Candida albicans (MIC=0.15-0.3 ¦ÌM), Candida glabrata (MIC=12.5-25 ¦ÌM), Candida tropicalis (MIC=3.15-6.25 ¦ÌM), Cryptococcus neoformans (MIC=0.8-1.6 ¦ÌM), Saccharomyces cerevisiae (MIC=1.6-3.15 ¦ÌM)."	[Ref.10942757] It exhibits 16% hemolysis at 1 ¦ÌM and 100 ¦ÌM against human erythrocytes	Cyclic	pyroglutamic acid	Amidation	"Disulfide bond between Cys2 and Cys15,Cys6 and Cys11."	L	No cytotoxicity information found	Not found	10942757	J Biol Chem. 2000 Oct 27;275(43):33464-70.	"Silva PI Jr, Daffre S, Bulet P."	"Isolation and characterization of gomesin, an 18-residue cysteine-rich defense peptide from the spider Acanthoscurria gomesiana hemocytes with sequence similarities to horseshoe crab antimicrobial peptides of the tachyplesin family."
DRAMP03098	HRHQGPIFDTRPSPFNPNQPRPGPIY	26	"Metchnikowin (Pro-rich; Insects, animals)"	"Q24395, Q24396, Q86BV8, Q9V7B9"	Not found	Mtk	Drosophila melanogaster (Common fruit fly)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Rich in Proline	Not found	None	Transgenic plants: Insect peptide metchnikowin confers on barley a selective capacity for resistance to fungal ascomycetes pathogens (J Exp Bot. 2009;60(14):4105-14). 	"Micrococcus luteus (MIC=0.5-1.0 ?g/ml), Neurospora crassa (MIC=0.5-1.0 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7588819	Eur J Biochem. 1995 Oct 15;233(2):694-700.	"Levashina E.A, Ohresser S, Bulet P, Reichhart JM, Hetru C, Hoffmann J.A."	"Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties."
DRAMP03113	SQLGDLGSGAGQGGGGGGSIRAAGGAFGKLEAAREEEFFYKKQKEQLERLKNDQIHQAEFHHQQIKEHEEAIQRHKDFLNNLHK	84	"SK84 (Gly-rich; Insects, animals)"	No entry found	Not found	Not found	Drosophila virilis (Fruit fly)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal, Antiviral"	Not found	Not found	Not found	None	"Function: SK84 displays antibacterial activity against the tested Gram-positive bacteria (B. subtilis, Bacillus thuringiensis and Staphylococcus aureus), but had no effect on Gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli) and fungi (Saccharomyces cerevisiae, Candida albicans). Has weak hemolytic activity."	"[Ref.19799950]Gram-positive bacteria: Bacillus thuringiensis ATCC 1041 (MIC=4 ?M), B. subtilis ATCC 9372 (MIC=8 ?M), Staphylococcus aureus ATCC 6538 (MIC=8 ?M)."	[Ref.19799950]0.01% hemolytic activity at 100 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19799950	Peptides. 2010 Jan;31(1):44-50.	"Lu J, Chen ZW."	"Isolation, characterization and anti-cancer activity of SK84, a novel glycine-rich antimicrobial peptide from Drosophila virilis."
DRAMP03138	GGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKAL	34	"Cecropin-A (Insects, animals)"	"P82592, Q17NR3, Q95PI9"	Belongs to the cecropin family	CECA	Aedes aegypti (Yellowfever mosquito)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli D22 (MIC=0.25-0.5 ?g/ml), E. coli D31 (MIC=0.25-0.5 ?g/ml), E. coli SBS363 (MIC=0.1-0.25 ?g/ml), E. coli 1106 (MIC=0.25-0.5 ?g/ml), Enterobacter cloacae b12 (MIC=50-100 ?g/ml), E. carotovora (MIC=0.25-0.5 ?g/ml), Klebsiella pneumoniae (MIC=1-2.5 ?g/ml), Pseudomonas aeruginosa (MIC=10-25 ?g/ml), Salmonella typhimurium (MIC=1-2.5 ?g/ml), X. campestris (MIC=0.5-1 ?g/ml);##Gram-positive bacteria: Aerococcus viridans (MIC=2.5-5 ?g/ml), Bacillus megaterium (MIC=1-2.5 ?g/ml), Micrococcus luteus (MIC=10-25 ?g/ml), Streptococcus pyogenes (MIC=10-25 ?g/ml).##Fungi: Fusarium culmorum (MIC=1-2.5 ?g/ml), Fusarium oxysporum (MIC=2.5-5 ?g/ml), Neurospora crassa (MIC=5-10 ?g/ml), Candida albicans (MIC=25-50 ?g/ml), Cryptococcus neoformans (MIC=25-50 ?g/ml), Saccharomyces cerevisiae (MIC=50-100 ?g/ml) "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10400619	J Biol Chem. 1999 Jul 16;274(29):20092-20097.	"Lowenberger C, Charlet M, Vizioli J, Kamal S, Richman A, Christensen BM, Bulet P."	"Antimicrobial activity spectrum, cDNA cloning, and mRNA expression of a newly isolated member of the cecropin family from the mosquito vector Aedes aegypti."
DRAMP03140	GRLKKLGKKIEGAGKRVFKAAEKALPVVAGVKALG	35	"Anopheles cecropin-A amidated isoform (Insects, animals)"	"P82290, A7XAX5, A7XAX7, A7XAY1, A7XAY8, A7XAZ7, A7XB12, A7XB23, Q7QEE3"	Belongs to the cecropin family	CecA	Anopheles gambiae (African malaria mosquito)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antibacterial activity against several Gram-positive and Gram-negative bacteria. Also has antifungal activity.
Tissue specificity: Relatively abundant in head, thorax and to a lesser extent in abdominal carcass and anterior midgut.
Developmental stage: In young pupae, expressed within 2 hours of infection and continued to accumulate over 16 hours.
Induction: By bacterial infection.
PTM: C-terminal amidation."	"Gram-negative bacteria: Alcaligenes faecalis (MIC=1-2.5 ?M), Escherichia coli 1106 (MIC=0.5-1 ?M), E. coli D22 (MIC=0.1-0.25 ?M), E. coli D31 (MIC=0.1-0.25 ?M), E. coli SBS363 (MIC=0.05-0.1 ?M), Enterobacter cloacae ¦Â12 (MIC=0.5-1 ?M), Erwinia carotovora (MIC=0.5-1 ?M), Klebsiella pneumoniae (MIC=1-2.5 ?M), Pseudomonas aeruginosa (MIC=1-2.5 ?M), Salmonella typhimurium (MIC=0.1-0.25 ?M), Xanthomonas campestris (MIC=0.5-1 ?M); ##Gram-positive bacteria: Aerococcus viridans (MIC=0.5-1 ?M), Bacillus cereus (MIC=50-100 ?M), Bacillus megaterium (MIC=0.5-1 ?M), Listeria monocytogenes (MIC=50-100 ?M), Micrococcus luteus (MIC=0.5-1 ?M), Staphylococcus aureus (MIC=50-100 ?M), Staphylococcus epidermidis (MIC=10-25 ?M), Staphylococcus haemolyticus (MIC=1-2.5 ?M), Staphylococcus saprophyticus (MIC=1-2.5 ?M), Streptococcus pyogenes (MIC=0.1-0.25 ?M).##Fungi: Aspergillus fumigatus (MIC=5-10 ?M), Botrytis cinerea (MIC=1-2.5 ?M), Fusarium culmorum (MIC=0.5-1 ?M), Fusarium oxysporum (MIC=1-2.5 ?M), Neurospora crassa (MIC=1-2.5 ?M), Candida albicans (MIC=1-2.5 ?M), Cryptococcus neoformans (MIC=5-10 ?M), Saccharomyces cerevisiae (MIC=25-50 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10672074##12421409	Insect Mol Biol. 2000 Feb;9(1):75-84.##Insect Mol Biol. 2002 Dec;11(6):517-525.	"Vizioli J, Bulet P, Charlet M, Lowenberger C, Blass C, M¨¹ller HM, Dimopoulos G, Hoffmann J, Kafatos FC, Richman A.##Zheng XL, Zheng AL."	"Cloning and analysis of a cecropin gene from the malaria vector mosquito, Anopheles gambiae.##Genomic organization and regulation of three cecropin genes in Anopheles gambiae."
DRAMP03150	MVFAYAPTCARCKSIGARYCGYGYLNRKGVSCDGQTTINSCEDCKRKFGRCSDGFITECFL	61	"Gambicin (Insects, animals)"	No entry found	Not found	Not found	Anopheles albimanus (mosquito)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiparasitic"	Not found	Bridge	Not found	None	"Function: In vitro experiments showed that the 6.8-kDa mature peptide can kill both Gram-positive and Gram-negative bacteria, has a morphogenic effect on a filamentous fungus, and is marginally lethal to Plasmodium berghei ookinetes.
Induction: Predominantly expressed in the anterior part.
PTM: Contains four disulfide bridges."	Gram-negative bacterium: E. coli (MIC=6.25-12.5 ?M);##Gram-positive bacterium: M. luteus (MIC=25-50 ?M).##Fungus: N. crassa.	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys9 and Cys20; Cys12 and Cys32; Cys41 and Cys51,Cys44 and Cys59."	L	No cytotoxicity information found	Not found	11606751	Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12630-5.	"Vizioli J, Bulet P, Hoffmann JA, Kafatos FC, M¨¹ller HM, Dimopoulos G."	Gambicin: a novel immune responsive antimicrobial peptide from the malaria vector Anopheles gambiae.
DRAMP03162	ATCDLLSAFGVGHAACAAHCIGHGYRGGYCNSKAVCTCRR	40	"Phlebotomus duboscqi defensin (PduDef; defensins; Insects, animals)"	P83404	Belongs to the invertebrate defensin family (Type 1 subfamily)	Not found	Phlebotomus duboscqi	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal, Antiparasitic"	Protein level	Bridge	Not found	None	"Function: Has antiparasitic and antifungal activity.
Tissue specificity: Is synthesized by the fat body and eventually secreted into the hemolymph.
Induction: By bacterial and parasitic hemolymph and gut infections. Expression peaks at 24 hours post infection by bacterium P. carotovorum, and at day four post infection by the parasite L. major. 
PTM: Problely contains three disulfide bonds 3-30; 16-36; 20-36."	"Gram-positive bacteria: Staphylococcus aureus (MIC=0.78-1.56 ?M), Aspergillus fumigatus (MIC=12.5-25 ?M).##Fungi: Fusarium culmorum (MIC=1.56-3.12 ?M), Fusarium oxysporum (MIC=3.12-6.25 ?M), Neurospora crassa (MIC=6.25-12.5 ?M), Trichoderma viride (MIC=3.12-6.25 ?M), Trichophyton mentagrophytes (MIC=25-50 ?M), Candida albicans (MIC=6.25-12.5 ?M), Saccharomyces cerevisiae (MIC=25-50 ?M).##Parasite: Leishmania major promastigote forms (IC50=68-85 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bonds between Cys3 and Cys30; Cys16 and Cys36; Cys20 and Cys36.	L	No cytotoxicity information found	Not found	15557638	Infect Immun. 2004 Dec;72(12):7140-7146.	"Boulanger N, Lowenberger C, Volf P, Ursic R, Sigutova L, Sabatier L, Svobodova M, Beverley SM, Sp?th G, Brun R, Pesson B, Bulet P."	Characterization of a defensin from the sand fly Phlebotomus duboscqi induced by challenge with bacteria or the protozoan parasite Leishmania major.
DRAMP03166	IRNSLTCRFNFGICLPKRCPGRMRQIGTCF	30	"P15 (deer beta-defensin; ruminant, animals)"	No entry found	Not found	Not found	Cervus elaphus (New Zealand deer)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: It shows strong activity against Gram-negative bacteria, but lesser activity against Gram-positive bacteria and yeast.
Caution: the sequence displayed is N-terminal sequence of P15. "	Gram-negative bacterium: Escherichia coli O111 (MIC=0.3 ?g/mL);##Gram-positive bacterium: Staphylococcus aureus NCTC 4163 (MIC=1 ?g/mL).##Fungi: Candida albicans 3135A (MIC=3 ?g/mL).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16011891	Int J Antimicrob Agents. 2005 Aug;26(2):165-169.	"Treffers C, Chen L, Anderson RC, Yu PL."	Isolation and characterisation of antimicrobial peptides from deer neutrophils.
DRAMP03173	RWCVYAYVRVRGVLVRYRRCW	21	"Arenicin-1 (Ar-1; marine polychaeta, animals)"	"Q5SC60, P84105"	Not found	Not found	Arenicola marina (Lugworm) (Lumbricus marinus)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Cytotoxic"	Protein level	Beta strand (2 strands; 16 residues)	"Arenicin-1 is a two-stranded antiparallel ¦Â-sheet (Cys3-Val10 and Val13-Cys20) stabilized by nine intra-backbone hydrogen bonds and a disulfide bond between Cys3 and Cys20. The strands of the ¦Â-sheet are connected by a type I? ¦Â-turn. The surface of arenicin is amphiphilic, with distinct hydrophobic and hydrophilic areas (ref.2)."	2JSB resolved by NMR.	"Function: Has antimicrobial activity against the Gram-negative bacteria, Gram-positive bacteriua as well as yeast C. albicans. Bacterial killing occurs within minutes and is accompanied by membrane permeabilization, membrane detachment and release of cytoplasm. Interaction of arenicin with reconstituted membranes that mimic the lipopolysaccharide-containing outer membrane or the phospholipid-containing plasma membrane of Gram-negative bacteria exhibited no pronounced lipid specificity.
PTM: Contains one disulfide bond 3-20.
Domian: Contains 1 BRICHOS domain."	"Gram-positive bacterium: Listeria monocytogenes EGD (MIC=0.6 ?g/ml);##Gram-negative bacteria: Escherichia coli ML-35p (MIC=4 ?g/ml), E. coli WBB01 (MIC=0.3 mM), E. coli ATCC 23716 (MIC=0.6 mM), Salmonella enterica R595 (MIC=0.3 mM), S. enterica R60 (MIC=1.25 mM), Proteus mirabilis R45 (MIC=0.6 mM).##Yeast: Candida albicans 820 (MIC=20 ?g/ml).##Human Jurkat T-cells: LD50>40 mM (35.5% lysis at 30 mM)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bond between Cys3 and Cys20.	L	"[Ref.27940358] Cytotoxicity: human embryonic fibroblasts (HEF) and human red blood cells (hRBC)(IC50 for arenicin-1 in the presence or absence of 10% FBS were of 35 and 8 ¦ÌM,HC50 indicating 50% hemolysis after 24 h incubation, equaled to 16¦ÌM)."	Anionic lipid vesicles	15527787##17935487	FEBS Lett. 2004 Nov 5;577(1-2):209-214.##Biochem J. 2008 Feb 15;410(1):113-122.	"Ovchinnikova TV, Aleshina GM, Balandin SV, Krasnosdembskaya AD, Markelov ML, Frolova EI, Leonova YF, Tagaev AA, Krasnodembsky EG, Kokryakov VN.##Andr? J, Jakovkin I, Gr?tzinger J, Hecht O, Krasnosdembskaya AD, Goldmann T, Gutsmann T, Leippe M."	"Purification and primary structure of two isoforms of arenicin, a novel antimicrobial peptide from marine polychaeta Arenicola marina.##Structure and mode of action of the antimicrobial peptide arenicin."
DRAMP03176	SWLSKTAKKLENSAKKRISEGIAIAIQGGPR	31	"Cecropin-P1 (CP1; nematodes, animals)"	"P14661, Q5H7N7"	Belongs to the cecropin family	ASCEC-1	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Has antibacterial activity against several Gram-positive and Gram-negative bacteria. Is weakly active against yeasts. Acts by a nonpore mechanism.
Induction: By bacterial infection."	"P1-NH2 (amidated cecropin P1): [E. coli K-12/ D21 (MIC=0.3 ?M), E. coli 853/67/0149/K88 (MIC=0.9 ?M), E. coli Bd2221/75/08/K88 (MIC=0.6 ?M), E. coli Bd4462/84/0101/K99 (MIC=0.7 ?M), E. coli Bd4466/84/064/K99 (MIC=0.3 ?M), Salmonella typhimurium LT2 (MIC=0.9 ?M), A. calcoaceticus Ac1l (MIC=0.2 ?M), Proteus vulgaris Pvll (MIC=5.7 ?M), Pseudomonas aeruginosa OT97 (MIC=5.9 ?M), Bacillus megaterium Bmll (MIC=1.8 ?M), Streptococcus pyogenes (MIC=19 ?M)].##P1-OH (non-amidated cecropin P1): [E. coli K-12/ D21 (MIC=0.4 ?M), E. coli 853/67/0149/K88 (MIC=0.6 ?M), E. coli Bd2221/75/08/K88 (MIC=0.7 ?M), E. coli Bd4462/84/0101/K99 (MIC=0.8 ?M), E. coli Bd4466/84/064/K99 (MIC=0.6 ?M), Salmonella typhimurium LT2 (MIC=1.7 ?M), A. calcoaceticus Ac1l (MIC=0.5 ?M), Proteus vulgaris Pvll (MIC=12 ?M), Pseudomonas aeruginosa OT97 (MIC=13 ?M), Bacillus megaterium Bmll (MIC=5.3 ?M), Streptococcus pyogenes (MIC=44 ?M)]."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15850460##1396696	Biochem J. 2005 Aug 15;390(Pt 1):207-214.##Eur J Biochem. 1992 Oct 1;209(1):163-169.	"llai A, Ueno S, Zhang H, Lee JM, Kato Y.##Sipos D, Andersson M, Ehrenberg A."	"Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum.##The structure of the mammalian antibacterial peptide cecropin P1 in solution, determined by proton-NMR."
DRAMP03181	HVDKKVADKVLLLKQLRIMRLLTRL	25	"Spinigerin (Insects, animals)"	P82357	Not found	Not found	Pseudacanthotermes spiniger (Termite)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	"1ZRW, 1ZRV resolved by NMR."	Function: Active against Gram-positive bacteria and Gram-negative bacteria and fungi.	"Gram-positive bacteria: Bacillus megaterium (MIC=0.8-1.5 ?M), Micrococcus luteus (MIC=0.8-1.5 ?M);##Gram-negative bacteria: Escherichia coli SBS363 (MIC=3-6 ?M), E. coli D22 (MIC=3-6 ?M), Klebsiella pneumoniae (MIC=50-100 ?M), Salmonella typhimurium (MIC=3-6 ?M), Pseudomonas aeruginosa (MIC=50-100 ?M).##Fungi: Trichoderma viride (MIC=1.5-3 ?M), Neurospora crassa (MIC=3-6 ?M), Fusarium culmorum (MIC=1.5-3 ?M), Nectria haematococca (MIC=0.4-0.8 ?M), Candida albicans (MIC=3-6 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11053427##16170803	J Biol Chem. 2001 Feb 9;276(6):4085-4092.##Biopolymers. 2006 Feb 5;81(2):92-103. 	"Lamberty M, Zachary D, Lanot R, Bordereau C, Robert A, Hoffmann JA, Bulet P.##Landon C, Meudal H, Boulanger N, Bulet P, Vovelle F."	"Insect immunity. Constitutive expression of a cysteine-rich antifungal and a linear antibacterial peptide in a termite insect.##Solution structures of stomoxyn and spinigerin, two insect antimicrobial peptides with an alpha-helical conformation."
DRAMP03186	SFGLCRLRRGFCARGRCRFPSIPIGRCSRFVQCCRRVW	38	"Spheniscin-2 (Sphe-2; penguin avian beta-defensin 103b; birds ,animals)"	P83430	Belongs to the beta-defensin family	Not found	Aptenodytes patagonicus (King penguin)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Beta strand (3 strands; 14 residues)	"The overall fold of Sphe-2 includes a three-stranded antiparallel beta-sheet stabilized by three disulfide bridges with a pairing typical of beta-defensins. In addition, the N-terminal segment shows helical features on most structures.(Ref.2)"	1UT3 resolved by NMR.	"Function: Has antimicrobial activity. Has insecticidal and hemolytic activities. Probably acts by disturbing membrane Function: with its amphipathic structure.
PTM: Contains three disulfide bond: 5-33; 12-27; 17-34.
Preserving food in the bird somach for several weeks during egg incubation. The disulfide bond pattern is identical to canonical beta-defensins from mammals. The high potency is related to its high cationicity as well as a hydrophobic patch, which is not observed in mammalian defensins. "	"[Ref.14525994]Gram-positive bacteria: Micrococcus luteus (MIC=1.5-3.0 ?M), Bacillus subtilis (MIC=0.8-1.5 ?M), Bacillus cereus ATCC 11778 (MIC=3-6 ?M), Bacillus megaterium (MIC=0.4-0.8 ?M), Staphylococcus aureus (MIC=1.5-3.0 ?M), Staphylococcus saprophyticus (MIC=1.5-3.0 ?M), Staphylococcus haemolyticus (MIC=1.5-3.0 ?M), Nocardia asteroides (MIC=0.8-1.5 ?M), Aerococcus viridans (MIC=0.4-0.8 ?M), Listeria monocytogenes (MIC=6-12 ?M);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=0.8-1.5 ?M), Escherichia coli 1106 (MIC=1.5-3.0 ?M), Salmonella typhimurium (MIC=6-12 ?M), Klebsiella pneumoniae (MIC=50-100 ?M), Pseudomonas aeruginosa ATCC 82118 (MIC=6-12 ?M), Vibrio metschnikovii NCTC 8483 (MIC=25-50 ?M), Vibrio anguillarum ATCC 19264 (MIC=25-50 ?M);##Fungi: Candida glabrata (MIC>100 ?M), Candida albicans IHEM 8060 (MIC=50-100 ?M), Candida tropicalis (MIC=1.5-3.0 ?M), Neurospora crassa (MIC=3-6 ?M),Aspergillus fumigatus (MIC=3-6 ?M)."	It has hemolytic activity	Cyclic	Free	Free	Disulfide bonds between Cys5 and Cys33; Cys12 and Cys27; Cys17 and Cys34.	L	No cytotoxicity information found	Not found	14525994##15123713	J Biol Chem. 2003 Dec 19;278(51):51053-51058.##J Biol Chem. 2004 Jul 16;279(29):30433-30439.	"Thouzeau C, Le Maho Y, Froget G, Sabatier L, Le Bohec C, Hoffmann JA, Bulet P.##Landon C, Thouzeau C, Labb¨¦ H, Bulet P, Vovelle F."	"Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus.##Solution structure of spheniscin, a beta-defensin from the penguin stomach."
DRAMP03187	QRYFCRVRGGRCAALTCLPRETQIGRCSVKGRKCCR	36	"Beta defensin 1(BD-1; mammals, animals)"	P83943	Belongs to the beta-defensin family	DEFB1	Chinchilla lanigera (Long-tailed chinchilla) 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has antibacterial and antifungal activity. May have a role in maintaining sterility in the middle ear.	Gram-negative bacterium: Moraxella catarrhalis (MIC=5 ?g/ml);##Gram-positive bacterium: Streptococcus pneumoniae (MIC=5 ?g/ml).##Fungi: Candida albicans (MIC=12.5-20 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14996845	J Biol Chem. 2004 May 7;279(19):20250-20256.	"Harris RH, Wilk D, Bevins CL, Munson RS Jr, Bakaletz LO."	Identification and characterization of a mucosal antimicrobial peptide expressed by the chinchilla (Chinchilla lanigera) airway.
DRAMP03190	RLGNFFRKAKKKIGRGLKKIGQKIKDFLGNLVPRTES	37	"PobRL-37 (cathelicidin; primates, mammals, animals)"	No entry found	Not found	Not found	Cercopithecidae	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Function: Has antibacterial activity.	"In 20% TSB in SPB medium: Escherichia coli (MIC=0.5 ?M), Pseudomonas aeruginosa (MIC=0.5-1 ?M), Staphylococcus aureus (MIC=2 ?M), Enterococcus faecalis (MIC=2-4 ?M).##In 20% SAB in SPB: Candida albicans (MIC=8-16 ?M). In 5% TSB in SPB: Escherichia coli (MIC=0.5 ?M). In 5% SAB in SPB: Candida albicans (MIC=4-8 ?M).##In 20% TSB in PIL: Escherichia coli (MIC=1 ?M), Pseudomonas aeruginosa (MIC=1-2 ?M); Staphylococcus aureus (MIC=0.5 ?M), Enterococcus faecalis (MIC=1-2 ?M).##In 20% SAB in PIL: Candida albicans (MIC=16 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16720578	J Biol Chem. 2006 Jul 21;281(29):19861-19871.	"Zelezetsky I, Pontillo A, Puzzi L, Antcheva N, Segat L, Pacor S, Crovella S, Tossi A."	Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity.
DRAMP03196	RCVCRRGVCRCVCTRGFC	18	"PhTD-1 (PhTD1; primates, mammals, animals)"	"P86722, P86723"	Not found	Not found	Papio hamadryas (Hamadryas baboon)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"In low salt conditions: Escherichia coli ML35p (MIC=1.5 ?M), Listeria monocytogenes EGD (MIC=1.6 ?M) and methicillin-resistant Staphylococcus aureus ATCC 33591 (MIC=2.5 ?M),.##Fungi: Candida albicans 820 (MIC=1.6 ?M);##At high physiological salt concentrations: Escherichia coli ML35p (MIC=2.0 ?M), Listeria monocytogenes EGD (MIC=1.7 ?M), Staphylococcus aureus ATCC 33591 (MIC=3.6 ?M), Candida albicans 820 (MIC=6.5 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	No specific N-terminal	No specific C-terminal	Disulfide bonds between Cys2 and Cys11; Cys4 and Cys9; Cys13 and Cys18.	L	No cytotoxicity information found	Not found	20155756	Rapid Commun Mass Spectrom. 2010 Mar 15;24(5):599-604.	"Stegemann C, Tsvetkova EV, Aleshina GM, Lehrer RI, Kokryakov VN, Hoffmann R."	De novo sequencing of two new cyclic theta-defensins from baboon (Papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry.
DRAMP03197	RCVCTRGFCRCVCTRGFC	18	"PhTD-3 (PhTD3; primates, mammals, animals)"	"P86722, P86723"	Not found	Not found	Papio hamadryas (Hamadryas baboon)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"In low salt conditions: Escherichia coli ML35p (MIC=1.7 ?M), Listeria monocytogenes EGD (MIC=1.5 ?M), Staphylococcus aureus ATCC 33591 (MIC=1.7 ?M), Candida albicans 820 (MIC=1.4 ?M);##At high physiological salt concentrations: Escherichia coli ML35p (MIC=2.2 ?M), Listeria monocytogenes EGD (MIC=1.9 ?M), Staphylococcus aureus ATCC 33591 (MIC=4.5 ?M), Candida albicans 820 (MIC=7.4 ?M). "	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	No specific N-terminal	No specific C-terminal	Disulfide bonds between Cys2 and Cys11; Cys4 and Cys9; Cys13 and Cys18.	L	No cytotoxicity information found	Not found	20155756	Rapid Commun Mass Spectrom. 2010 Mar 15;24(5):599-604.	"Stegemann C, Tsvetkova EV, Aleshina GM, Lehrer RI, Kokryakov VN, Hoffmann R."	De novo sequencing of two new cyclic theta-defensins from baboon (Papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry.
DRAMP03198	ACYCRIPACFAGERRYGTCFYLGRVWAFCC	30	"Alpha-defensin PhD-4 (primates, mammals, animals)"	P86724	Belongs to the alpha-defensin family	Not found	Papio hamadryas (Hamadryas baboon)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antibacterial activity in low salt conditions, and the antimicrobial activity decreases significantly at high physiological salt concentrations.
PTM: Contains three disulfide bonds (By similarity)."	"In low salt conditions: Gram-negative bacterium: E. coli ML35p (MIC=2.4 ?M),;##Gram-positive bacteria: Listeria monocytogenes EGD (MIC=2.2 ?M), methicillin-resistant S. aureus ATCC 33591 (MIC=3.5 ?M).##Fungi: Candida albicans 820 (MIC=3.9 ?M).##At high physiological salt concentrations: E. coli ML35p (MIC=7.1 ?M), L. monocytogenes EGD (MIC=1.8 ?M), S. aureus ATCC 33591 (MIC>50 ?M), Candida albicans 820 (MIC>50 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20155756	Rapid Commun Mass Spectrom. 2010 Mar 15;24(5):599-604.	"Stegemann C, Tsvetkova EV, Aleshina GM, Lehrer RI, Kokryakov VN, Hoffmann R."	De novo sequencing of two new cyclic theta-defensins from baboon (Papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry.
DRAMP03215	ZCRRLCYKQRCVTYCRGR	18	"Gomesin (Gm; spiders, Arthropods, animals)"	"P82358, Q86RA2"	Not found	Not found	Acanthoscurria gomesiana (Tarantula spider)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Protein level	Beta strand	"Gm adopts a well-defined ¦Â-hairpin-like struc ture, and the disulfide bonds have been reported to be important for the maintenance of this structure."	1KFP resolved by NMR.	"[Ref.10942757]Function: Gomesin bound to the cell surface of cryptococci neoformans, which resulted in cell death associated with membrane permeabilization (FEMS Microbiol Lett. 2007 Sep;274(2):279-86). Also, this peptide triggers SH-SY5Y cell death through L-type channel calcium influx, MAPK/ERK, PKC and PI3K signaling and generation of reactive oxygen species (Soletti RC et al 2010 Chem Biol Interact 186: 135-43). Although represented by E, the N-terminal residue is a pyroglutamate. In hemocytes only, but not in all hemocytes observed.##[Ref.28741926]Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.10942757]Gram-positive bacteria: Aerococcus viridans (MIC=0.8-1.6 ?M), Bacillus cereus (MIC=6.25-12.5 ?M), Bacillus megaterium (MIC=0.2-0.4 ?M), Bacillus thuringiensis (MIC=1.6-3.15 ?M), Enterococcus faecalis (MIC=6.2-12.5 ?M), Listeria monocytogenes (MIC=0.8-1.6 ?M), Micrococcus luteus (MIC=0.4-0.8 ?M), Pediococcus acidolacrici (MIC=3.15-6.25 ?M), Staphylococcus aureus (MIC=1.6-3.15 ?M), S. epidermidis (MIC=0.8-1.6 ?M), S. haemolyticus (MIC=0.8-1.6 ?M), S. saprophyticus (MIC=0.8-1.6 ?M), Streptococcus pyogenes (MIC=1.6-3.15 ?M), Nocardia asteroides (MIC=1.6-3.15 ?M);##Gram-negative bacteria: Alcaligenes faecalis (MIC>100 ?M), Escherichia coli 1106 (MIC=0.8-1.6 ?M), E. coli D22 (MIC=0.4-0.8 ?M), E. coli D31 (MIC=0.8-1.6 ?M), E. coli SBS363 (MIC=0.4-0.8 ?M), Erwinia carolovora carolovora (MIC=3.15-6.25 ?M), Enterobacter cloacae beta 12 (MIC=3.15-6.25 ?M), Klebsiella pneumoniae (MIC=3.15-6.25 ?M), Pseudomonas aeruginosa (MIC=1.6-3.15 ?M), Salmonella typhimurium (MIC=0.8-1.6 ?M), Xhantomonas campestris pv. orizae (MIC=3.15-6.25 ?M).##Fungi: Alternaria brassicola (MIC=0.4-0.8 ?M), Aspergillus fumigatus (MIC=1.6-3.15 ?M), Beauveria bassiana (MIC=12.5-25 ?M), Fusarium culmorum (MIC=0.4-0.8 ?M), F. oxysporum (MIC=0.4-0.8 ?M), Neurospora crassa (MIC=0.4-0.8 ?M), Nectria haematococca (MIC=0.2-0.4 ?M), Tricoderma viridae (MIC=0.4-0.8 ?M), Tricophvton mentagrophytes (MIC=0.8-1.6 ?M), C. albicans (MIC=0.15-0.3 ?M), C. glabrata (MIC=12.5-25 ?M), C. tropicalis (MIC=3.15-6.25 ?M), C. neoformans (MIC=0.8-1.6 ?M), Saccharomyces cerevisiae (MIC=1.6-3.15 ?M).##[Ref.28741926]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=32 ¦ÌM);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=4 ¦ÌM), Klebsiella pneumoniae ATCC 700603 (MIC=32 ¦ÌM), Acinetobacter baumannii ATCC 19606 (MIC=4-8 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC=8 ¦ÌM), Helicobacter pylori ATCC 43504 (MIC>80 ¦ÌM);##Fungi : Candida albicans ATCC 90028 (MIC=8-16 ¦ÌM), Cryptococcus neoformans ATCC 208821 (MIC=0.5-1 ¦ÌM)"	"[Ref.28741926] It has 0% hemolysis at 6 ¦ÌM , 3% hemolysis at 10 ¦ÌM , 10% hemolysis at 5 ¦ÌM , 41.2-53.2% hemolysis at 64 ¦ÌM , 50% hemolysis at 100 ¦ÌM against human red blood cells"	Cyclic	pyroglutamic acid	Amidation 	"Disulfide bond between Cys2 and Cys15,Cys6 and Cys11."	L	"[Ref.28741926] CC50 = 67.0 ¡À 5.0 ¦ÌM against CRL-1739, CC50 = 3.7 ¡À 0.2 ¦ÌM against MM96L, CC50 = 49.9 ¡À16.6¦ÌM against HFF-1, CC50 =54.1¡À5.0 ¦ÌM against HeLa, CC50 = 3.8 ¡À 0.3 ¦ÌM against K-562."	Not found	10942757##28741926	J Biol Chem. 2000 Oct 27;275(43):33464-33470.##ACS Chem Biol.?2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459.?	"Silva PI Jr, Daffre S, Bulet P.##Sonia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval,Aurelie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan,Yen-Hua Huang, and David J. Craik"	"Isolation and characterization of gomesin, an 18-residue cysteine-rich defense peptide from the spider Acanthoscurria gomesiana hemocytes with sequence similarities to horseshoe crab antimicrobial peptides of the tachyplesin family.##Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties"
DRAMP03226	SMWSGMWRRKLKKLRNALKKKLKGE	25	"M-zodatoxin-Lt1a (M-ZDTX-Lt1a; Latarcin-1, Ltc-1, Ltc1; spiders, Arthropods, animals)"	Q1ELT9	Belongs to the latarcin family	Not found	Lachesana tarabaevi (Spider)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix (1 helices; 16 residues)	The Ltc1 molecule is found to form a straight uninterrupted amphiphilic helix comprising 8-23 residues. The hydrophobic surface of the Ltc1 helix is narrow-shaped and extends with no gradient along the axis. (Ref.2)	2PCO resolved by NMR.	"Function: Has hemolytic activity against Rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae."	"[Ref.16735513]Gram-positive bacteria: Arthrobacter globiformis VKM Ac-1112 (MIC=0.5 ?M), Bacillus subtilis VKM B-501 (MIC=1.0 ?M);##Gram-negative bacteria: Escherichia coli DH5-alpha (MIC=1.0 ?M), Escherichia coli MH1 (MIC=0.7?M), Pseudomonas aeruginosa PAO1 (MIC=4.1 ?M);##Fungi: Pichia pastoris GS115 (MIC=17 ?M), Saccharomyces cerevisiae Y190 (MIC>33 ?M)."	[Ref.16735513]20% hemolytic activity at 80 ¦ÌM against rabbit erythrocytes 	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16735513##18293934	J Biol Chem. 2006 Jul 28;281(30):20983-20992.##Biochemistry. 2008 Mar 18;47(11):3525-3533.	"Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV.##Dubovskii PV, Volynsky PE, Polyansky AA, Karpunin DV, Chupin VV, Efremov RG, Arseniev AS."	"Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity.##Three-dimensional structure/hydrophobicity of latarcins specifies their mode of membrane activity."
DRAMP03227	GLFGKLIKKFGRKAISYAVKKARGKH	26	"M-zodatoxin-Lt2a (M-ZDTX-Lt2a; Latarcin-2a, Ltc-2a, Ltc2a; spiders, Arthropods, animals)"	Q1ELU1	Belongs to the latarcin family	Not found	Lachesana tarabaevi (Spider)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix (2 helices; 18 residues)	The molecule of Ltc2a is found to consist of two helical regions (residues 3-9 and 13-21) connected via a poorly ordered fragment.	2G9P resolved by NMR.	"Function: Has hemolytic activity against Rabbit erythrocytes and has toxicity to ovarian insect Sf9 cells (EC50=20 ?M). Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae. "	"[Ref.16735513]Gram-positive bacteria: Arthrobacter globiformis VKM Ac-1112 (MIC=0.7 ?M), Bacillus subtilis VKM B-501 (MIC=0.4 ?M);##Gram-negative bacteria: Escherichia coli DH5-alpha (MIC=1.0 ?M), Escherichia coli MH1 (MIC=0.7 ?M), Pseudomonas aeruginosa PAO1 (MIC=6.7 ?M);##Fungi: Pichia pastoris GS115 (MIC=6.7 ?M), Saccharomyces cerevisiae Y190 (MIC=54 ?M)."	[Ref.16735513]20% hemolytic activity at 6 ¦ÌM against rabbit erythrocytes 	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16735513##16939228	J Biol Chem. 2006 Jul 28;281(30):20983-20992.##Biochemistry. 2006 Sep 5;45(35):10759-10767.	"Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV.##Dubovskii PV, Volynsky PE, Polyansky AA, Chupin VV, Efremov RG, Arseniev AS."	"Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity.##Spatial structure and activity mechanism of a novel spider antimicrobial peptide."
DRAMP03229	SWKSMAKKLKEYMEKLKQRA	20	"M-zodatoxin-Lt3a (M-ZDTX-Lt3a; Latarcin-3a, Ltc-3a; spiders, Arthropods, animals)"	Q1ELU3	Belongs to the latarcin family	Not found	Lachesana tarabaevi (Spider)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Has hemolytic activity against Rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae.
Tissue specificity: Expressed by the venom gland."	"[Ref.16735513]Gram-positive bacteria: Arthrobacter globiformis VKM Ac-1112 (MIC=0.3 ?M), Bacillus subtilis VKM B-501 MIC=1.2 ?M);##Gram-negative bacteria: Escherichia coli DH5-alpha (MIC=2.5 ?M), Escherichia coli MH1 (MIC=6.0 ?M), Pseudomonas aeruginosa PAO1 (MIC>40 ?M);##Fungi: Pichia pastoris GS115 (MIC=20 ?M), Saccharomyces cerevisiae Y190 (MIC=20 ?M)."	[Ref.16735513]20% hemolytic activity at >120 ¦ÌM against rabbit erythrocytes 	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16735513	J Biol Chem. 2006 Jul 28;281(30):20983-209892.	"Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV."	"Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity."
DRAMP03230	SWASMAKKLKEYMEKLKQRA	20	"M-zodatoxin-Lt3b (M-ZDTX-Lt3b; Latarcin-3b, Ltc-3b; spiders, Arthropods, animals)"	Q1ELU2	Belongs to the latarcin family	Not found	Lachesana tarabaevi (Spider)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Has hemolytic against Rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae.
Tissue specificity: Expressed by the venom gland."	"[Ref.16735513]Gram-positive bacteria: Arthrobacter globiformis VKM Ac-1112 (MIC=0.7 ?M), Bacillus subtilis VKM B-501 (MIC=2.9 ?M);Gram-negative bacteria: Escherichia coli DH5-alpha (MIC=23 ?M), Escherichia coli MH1 (MIC=28 ?M), Pseudomonas aeruginosa PAO1 (MIC>45 ?M);##Fungi: Pichia pastoris GS115 (MIC=23 ?M), Saccharomyces cerevisiae Y190 (MIC=23 ?M)."	[Ref.16735513]20% hemolytic activity at >120 ¦ÌM against rabbit erythrocytes 	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16735513	J Biol Chem. 2006 Jul 28;281(30):20983-209892.	"Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV."	"Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity."
DRAMP03231	GLKDKFKSMGEKLKQYIQTWKAKF	24	"M-zodatoxin-Lt4a (M-ZDTX-Lt4a; Latarcin-4a, Ltc-4a; spiders, Arthropods, animals)"	Q1ELU5	Belongs to the latarcin family	Not found	Lachesana tarabaevi (Spider)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Has hemolytic activity against Rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae.
Tissue specificity: Expressed by the venom gland."	"[Ref.16735513]Gram-positive bacteria: Arthrobacter globiformis VKM Ac-1112 (MIC=0.3 ?M), Bacillus subtilis VKM B-501 (MIC=1.1 ?M);##Gram-negative bacteria: Escherichia coli DH5-alpha (MIC=4.5 ?M), Escherichia coli MH1 (MIC=3.2 ?M), Pseudomonas aeruginosa PAO1 (MIC>35 ?M);##Fungi: Pichia pastoris GS115 (MIC=36 ?M), Saccharomyces cerevisiae Y190 (MIC=18 ?M)."	[Ref.16735513]20% hemolytic activity at >120 ¦ÌM against rabbit erythrocytes 	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16735513	J Biol Chem. 2006 Jul 28;281(30):20983-209892.	"Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV."	"Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity."
DRAMP03232	SLKDKVKSMGEKLKQYIQTWKAKF	24	"M-zodatoxin-Lt4b (M-ZDTX-Lt4b; Latarcin-4b, Ltc-4b; spiders, Arthropods, animals)"	Q1ELU4	Belongs to the latarcin family	Not found	Lachesana tarabaevi (Spider)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Has hemolytic activity against Rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae.
Tissue specificity: Expressed by the venom gland."	"[Ref.16735513]Gram-positive bacteria: Arthrobacter globiformis VKM Ac-1112 (MIC=0.3 ?M), Bacillus subtilis VKM B-501 (MIC=1.1 ?M);##Gram-negative bacteria: Escherichia coli DH5-alpha (MIC=4.4 ?M), Escherichia coli MH1 (MIC=4.4 ?M), Pseudomonas aeruginosa PAO1 (MIC>35 ?M);##Fungi: Pichia pastoris GS115 (MIC>35 ?M), Saccharomyces cerevisiae Y190 (MIC=35 ?M)."	[Ref.16735513]20% hemolytic activity at >120 ¦ÌM against rabbit erythrocytes 	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16735513	J Biol Chem. 2006 Jul 28;281(30):20983-209892.	"Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV."	"Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity."
DRAMP03233	GFFGKMKEYFKKFGASFKRRFANLKKRL	28	"M-zodatoxin-Lt5a (M-ZDTX-Lt5a; Latarcin-5, Ltc-5; spiders, Arthropods, animals)"	Q1ELU9	Belongs to the latarcin family	Not found	Lachesana tarabaevi (Spider)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacteria and Gram-negative bacteria and and yeasts. Also has hemolytic activity against rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae.
Tissue specificity: Expressed by the venom gland. PTM: Leucine amide at L28."	"[Ref.16735513]Gram-positive bacteria: Arthrobacter globiformis VKM Ac-1112 (MIC=1.1 ?M), Bacillus subtilis VKM B-501 (MIC=0.6 ?M);##Gram-negative bacteria: Escherichia coli DH5-alpha (MIC=0.6 ?M), Escherichia coli MH1 (MIC=0.6 ?M), Pseudomonas aeruginosa PAO1 (MIC=18 ?M);##Fungi: Pichia pastoris GS115 (MIC>37 ?M), Saccharomyces cerevisiae Y190 (MIC>37 ?M)."	[Ref.16735513]20% hemolytic activity at 40 ¦ÌM against rabbit erythrocytes 	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16735513	J Biol Chem. 2006 Jul 28;281(30):20983-20992. 	"Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV. "	"Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity."
DRAMP03253	GKLQAFLAKMKEIAAQTL	18	"M-lycotoxin-Ls3a (M-LCTX-Ls3a; Lycocitin-1; spiders, Arthropods, animals)"	P0C2U6	Not found	Not found	Lycosa singoriensis (Wolf spider) (Aranea singoriensis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Inhibits growth of Gram-positive and Gram-negative bacteria and fungi.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation."	"Gram-positive bacteria: Staphylococcus aureus, Bacillus subtilis ATCC6633 (MIC=1.6-3.2 ?M);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=3.2-6.4 ?M), Pseudomonas aeruginosa.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14991689	J Mass Spectrom. 2004 Feb;39(2):193-201.	"Budnik BA, Olsen JV, Egorov TA, Anisimova VE, Galkina TG, Musolyamov AK, Grishin EV, Zubarev RA."	De novo sequencing of antimicrobial peptides isolated from the venom glands of the wolf spider Lycosa singoriensis.
DRAMP03254	GRLQAFLAKMKEIAAQTL	18	"M-lycotoxin-Ls3b (M-LCTX-Ls3b; Lycocitin-2; spiders, Arthropods, animals)"	P0C2U7	Not found	Not found	Lycosa singoriensis (Wolf spider) (Aranea singoriensis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Inhibits growth of Gram-positive and Gram-negative bacteria and fungi.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation."	"Gram-positive bacteria: Staphylococcus aureus 209P, Bacillus subtilis ATCC 6633 (MIC=1.57-3.14 ?M);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=3.14-6.29 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=5.02-10.05 ?M).##Fungi: Candida albicans. "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14991689	J Mass Spectrom. 2004 Feb;39(2):193-201.	"Budnik BA, Olsen JV, Egorov TA, Anisimova VE, Galkina TG, Musolyamov AK, Grishin EV, Zubarev RA."	De novo sequencing of antimicrobial peptides isolated from the venom glands of the wolf spider Lycosa singoriensis.
DRAMP03278	IWLTALKFLGKHAAKHLAKQQLSKL	25	"M-lycotoxin-Hc1a (M-LCTX-Hc1a; Lycotoxin I; spiders, Arthropods, animals)"	P61507	Not found	Not found	Hogna carolinensis (Carolina wolf spider) (Lycosa carolinensis) 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Forms pore that permeabilize the cell membrane. Promotes efflux of calcium from synaptosomes, causes hemolysis, and dissipates voltage gradients across muscle membrane. Potently inhibits the growth of bacteria, yeast and Leishmania. Is lethal to lepidopteran larvae. May Function: both in the prey capture strategy as well as protection from infectious organisms arising from prey ingestion."	"Gram-positive bacteria: Bacillus thuringiensis subsp. Israelensis (MIC<5.0 ?M);##Gram-negative bacteria: Escherichia coli D31 (MIC=10-20 ?M), Escherichia coli DH5 (MIC=80-150 ?M).##Fungi: Candida glabrata ATCC 2001 (MIC=100-150 ?M), Candida albicans clinical isolate (MIC=100-200 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	9442044##18098329 	J Biol Chem. 1998 Jan 23;273(4):2059-2066.##J Pept Sci. 2008 Apr;14(4):528-534.	"Yan L, Adams ME.##Ad?o R, Seixas R, Gomes P, Pessoa JC, Bastos M."	"Lycotoxins, antimicrobial peptides from venom of the wolf spider Lycosa carolinensis.##Membrane structure and interactions of a short Lycotoxin I analogue."
DRAMP03279	KIKWFKTMKSIAKFIAKEQMKKHLGGE	27	"M-lycotoxin-Hc2a (M-LCTX-Hc2a; Lycotoxin-2; Lycotoxin II; spiders, Arthropods, animals)"	P61508	Not found	Not found	Hogna carolinensis (Carolina wolf spider) (Lycosa carolinensis) 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Forms pore that permeabilize the cell membrane. Promotes efflux of calcium from synaptosomes, causes hemolysis, and dissipates voltage gradients across muscle membrane. Potently inhibits the growth of bacteria, yeast and Leishmania. May Function: both in the prey capture strategy as well as protection from infectious organisms arising from prey ingestion."	"Gram-positive bacteria: Bacillus thuringiensis subsp. Israelensis (MIC=10-60 ?M);##Gram-negative bacteria: Escherichia coli D31 (MIC<10 ?M), Escherichia coli DH5 (MIC<40 ?M).##Fungi: Candida glabrata ATCC 2001 (MIC=100-150 ?M)"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	9442044##18098329	J Biol Chem. 1998 Jan 23;273(4):2059-2066.##J Pept Sci. 2008 Apr;14(4):528-534.	"Yan L, Adams ME.##Ad?o R, Seixas R, Gomes P, Pessoa JC, Bastos M."	"Lycotoxins, antimicrobial peptides from venom of the wolf spider Lycosa carolinensis.##Membrane structure and interactions of a short Lycotoxin I analogue."
DRAMP03280	ATYDGKCYKKDNICKYKAQSGKTAICKCYVKVCPRDGAKCEFDSYKGKCYC	51	AcAMP (A. clavatus antimicrobial peptide)	No entry found	Not found	Not found	Aspergillus clavatus ES1	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral, Antifungal"	Not found	Not found	Not found	None	"This basic, Cys-rich antifungal peptide is also active against bacteria. AcAMP was sensitive to proteolytic enzymes, stable between pH 5.0 and 10.0, and heat resistant (15 min at 100 degrees C). "	"Gram-positive bacteria: Staphylococcus aureus (MIC=20 ?g/ml), Bacillus cereus (MIC=10 ?g/ml), Micrococcus luteus (MIC=10 ?g/ml), Enterococcus faecalis (MIC=50 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=30 ?g/ml), Pseudomonas aeruginosa (MIC=50 ?g/ml).##Fungi: Aspergillus niger, Fusarium solani, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20440534	J Ind Microbiol Biotechnol. 2010 Aug;37(8):805-813.	"Hajji M, Jellouli K, Hmidet N, Balti R, Sellami-Kamoun A, Nasri M."	A highly thermostable antimicrobial peptide from Aspergillus clavatus ES1: biochemical and molecular characterization.
DRAMP03286	APGNKAECEREKGYCGFLKCSFPFVVSGKCSRFFFCCKNIW	41	"Ostricacin-2 (Beta-defensin 1; Birds, animals)"	P85114	Belongs to the beta-defensin family	Not found	Struthio camelus (Ostrich)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	PTM: Contains three disulfide bonds 8-36; 15-30; 20-37.	Gram-positive bacterium: Staphylococcus aureus 1056-MRSA (MIC=1.25 ?g/ml);##Gram-negative bacterium: Escherichia coli O157:H7 (MIC=0.96 ?g/ml);##Yeast: Candida albicans 3153A (MIC=6.2 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys8 and Cys36,Cys15 and Cys30,Cys20 and Cys37."	L	No cytotoxicity information found	Not found	16459058	Int J Antimicrob Agents. 2006 Mar;27(3):229-235.	"Sugiarto H, Yu PL."	Identification of three novel ostricacins: an update on the phylogenetic perspective of beta-defensins.
DRAMP03321	VISIIPV	7	Colutellin-A	P86168	Not found	Not found	Colletotrichum dematium (Anthracnose fungus)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Sclerotinia sclerotiorum (MIC=32.4 ?g/ml after 288 hours), Botrytis cinerea (MIC=10.8 ?g/ml after 288 hours),Fusarium solani, Aspergillus fumigatus, Geotrichum candidum."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	No specific N-terminal	No specific C-terminal	None	L	[Ref.18599825] It has less cytotoxicity against human PBMCs.	Not found	18599825	Microbiology. 2008 Jul;154(Pt 7):1973-1979.	"Ren Y, Strobel GA, Graff JC, Jutila M, Park SG, Gosh S, Teplow D, Condron M, Pang E, Hess WM, Moore E."	"Colutellin A, an immunosuppressive peptide from Colletotrichum dematium."
DRAMP03405	GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPE	33	"mCRAMP-1 (mouse cathelin-related antimicrobial peptide 1; cathelicidin; Rodents, mammals, animals"	"P51437, Q0VB78"	Not found	Camp	Mus musculus (Mouse)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Alpha helix (CD)	The spectra of 10-25 ?m synthetic CRAMP-1 in buffer suggest that the peptide is in a random coil configuration and that it will assume a helical structure in the presence of 15¨C45% (v/v) trifluoroethanol.	None	"Function: Acts as a potent antimicrobial peptide.
Tissue specificity: Expressed in testis, spleen, stomach, and intestine. Very low expression found in heart, lung and skeletal muscle. No expression in brain, kidney or liver."	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=1 ?M), Escherichia coli ML35 (MIC=2 ?M), Escherichia coli D21 (MIC=8 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=4 ?M), Serratia marcescens ATCC 8100 (MIC=4 ?M);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=32 ?M), Staphylococcus aureus Cowan I (MIC=32 ?M), Staphylococcus aureus (MRSA) (MIC>64 ?M), Staphylococcus aureus (MRSA) (MIC=64 ?M), Staphylococcus epidermidis ATCC 12228 (MIC=16 ?M), Streptococcus faecalis ATCC 29212 (MIC=16 ?M), Bacillus megaterium Bm11 (MIC=4 ?M).##Fungi: Candida albicans (MIC>64 ?M), Cryptococcus neoformans (MIC=16 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9148921##8706928	J Biol Chem. 1997 May 16;272(20):13088-13093.##FEBS Lett. 1996 Aug 5;391(1-2):5-8.	"Gallo RL, Kim KJ, Bernfield M, Kozak CA, Zanetti M, Merluzzi L, Gennaro R.##Popsueva AE, Zinovjeva MV, Visser JW, Zijlmans JM, Fibbe WE, Belyavsky AV."	"Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse.##A novel murine cathelin-like protein expressed in bone marrow."
DRAMP03406	ISRLAGLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPE	38	"mCRAMP-2 (mouse cathelin-related antimicrobial peptide 2; cathelicidin; Rodents, mammals, animals"	"P51437, Q0VB78"	Not found	Camp	Mus musculus (Mouse)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Alpha helix (CD)	The CD spectra of CRAMP-2 (not shown) were similar to CRAMP-1.	None	"Function: Acts as a potent antimicrobial peptide.
Tissue specificity: Expressed in testis, spleen, stomach, and intestine. Very low expression found in heart, lung and skeletal muscle. No expression in brain, kidney or liver."	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=1 ?M), Escherichia coli ML35 (MIC=2 ?M), Escherichia coli D21 (MIC=8 ?M), Pseudomonas aeruginosa ATCC 27853 (MIC=4 ?M), Serratia marcescens ATCC 8100 (MIC=4 ?M);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=32 ?M), Staphylococcus aureus Cowan I (MIC=32 ?M), Staphylococcus aureus (MRSA) (MIC>64 ?M), Staphylococcus aureus (MRSA) (MIC=64 ?M), Staphylococcus epidermidis ATCC 12228 (MIC=16 ?M), Streptococcus faecalis ATCC 29212 (MIC=32 ?M), Bacillus megaterium Bm11 (MIC=4 ?M).##Fungi: Candida albicans (MIC>64 ?M), Cryptococcus neoformans (MIC=16 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9148921##8706928	J Biol Chem. 1997 May 16;272(20):13088-13093.##FEBS Lett. 1996 Aug 5;391(1-2):5-8.	"Gallo RL, Kim KJ, Bernfield M, Kozak CA, Zanetti M, Merluzzi L, Gennaro R.##Popsueva AE, Zinovjeva MV, Visser JW, Zijlmans JM, Fibbe WE, Belyavsky AV."	"Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse.##A novel murine cathelin-like protein expressed in bone marrow."
DRAMP03419	VTCYCRRTRCGFRERLSGACGYRGRIYRLCCR	32	"Neutrophil antibiotic peptide NP-1 (RatNP-1; Rodents, mammals, animals)"	Q62716	Belongs to the alpha-defensin family	Not found	Rattus norvegicus (Rat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Comment: Active in vitro against S. aureus, fungi, Gram-positive and Gram-negative bacteria and to a lesser extent against an enveloped virus."	"Gram-positive bacterium: Staphylococcus aureus 502A [18 h] (MIC<100 cfu/ml);##Gram-negative bacterium: Escherichia coli ML-35 [18 h] (MIC<100 cfu/ml).##Fungi: Candida albicans 820 [18 h] (MIC<100 cfu/ml), Cryptococcus neoformans A-383 [18 h] (MIC=1.7 x 102 cfu/ml). "	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys3 and Cys31,Cys5 and Cys20,Cys10 and Cys30."	L	No cytotoxicity information found	Not found	2543629##7594610	Infect. Immun. 1989;57:2021-2027.##J. Immunol. 1995;155:4476-4484.	"Eisenhauer P.B, Harwig S.S.S.L, Szklarek D, Ganz T, Selsted M.E, Lehrer R.I.##Yount N.Y, Wang MS.C, Yuan J, Banaiee N, Ouellette A.J, Selsted M.E."	Purification and antimicrobial properties of three defensins from rat neutrophils.##Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis.
DRAMP03422	ACYCRIGACVSGERLTGACGLNGRIYRLCCR	31	"Neutrophil antibiotic peptide NP-4 (RatNP-4; Rodents, mammals, animals)"	Q62714	Belongs to the alpha-defensin family	Np4	Rattus norvegicus (Rat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral, Antifungal"	Protein level	Bridge	Not found	None	"Active in vitro against S. aureus, fungi, Gram-positive and Gram-negative bacteria and to a lesser extent against an enveloped virus."	"Gram-positive bacterium: Staphylococcus aureus 502A (MIC=50 ?g/ml);##Gram-negative bacteria: Escherichia coli ML-35, Acinetobacter calcoaceticus (MIC=50 ?g/ml).Fungi: Cryptococcus neoformans (MIC=10 ?g/ml), Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys2 and Cys30,Cys4 and Cys19,Cys9 and Cys29."	L	No cytotoxicity information found	Not found	2543629##7594610	Infect. Immun. 1989;57:2021-2027.##J. Immunol. 1995;155:4476-4484.	"Eisenhauer P.B, Harwig S.S.S.L, Szklarek D, Ganz T, Selsted M.E, Lehrer R.I.##Yount N.Y, Wang MS.C, Yuan J, Banaiee N, Ouellette A.J, Selsted M.E."	Purification and antimicrobial properties of three defensins from rat neutrophils.##Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis.
DRAMP03464	GLLNGLALRLGKRALKKIIKRLCR	24	"Cryptonin (Insects, animals)"	P85028	Not found	Not found	Cryptotympana dubia (Korean horse cicada)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	Function: Has very low hemolytic activity on rat erythrocytes. 	"[Ref.18000874]Gram-positive bacteria: Bacillus subtilis KCTC 3086 (MIC=3.12 ?g/ml), Staphylococcus aureus KCTC 1928 (MIC=25 ?g/ml), Micrococcus luteus KCTC 3063 (MIC=1.56 ?g/ml), Staphylococcus aureus (MRSA) (MIC=25 ?g/ml), VRE (MIC=25 ?g/ml);##Gram-negative bacteria: Escherichia coli K12-594 (MIC=3.12 ?g/ml);##Fungi: Candida albicans KCTC 7965 (MIC=50 ?g/ml), Candida tropicalis KCTC 1925 (MIC=3.12 ?g/ml)."	[Ref.18000874]<5% hemolytic activity at 25-200 ?g/ml against rat erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18000874	Arch Insect Biochem Physiol. 2007 Dec;66(4):204-213.	"Leem JY, Park DS, Suh EY, Hur JH, Oh HW, Park HY."	"Isolation and functional analysis of a 24-residue linear alpha-helical antimicrobial peptide from Korean blackish cicada, Cryptotympana dubia (Homoptera)."
DRAMP03465	NEYHGFVDKANNENKRKKQQGRDDFVVKPNNFANRRRKDDYNENYYDDVDAADVV	55	"Cicadin (Insects, animals)"	P83282	Not found	Not found	Cicada flammata 	"Antimicrobial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity against B.cinerea, M.arachidicola, F.oxysporum, R.solani and C.comatus. Suppresses the activity of HIV-1 reverse transcriptase and stimulates the proliferation of murine splenocytes."	"Fungi: Botrytis cinerea (MIC=100 nM), Mycosphaerella arachidicola (MIC=70 nM), Fusarium oxysporum (MIC=180 nM), Physalospora piricola (MIC=60 nM), Rhizoctonia solani, Coprinus comatus, HIV-1 reverse transcriptase."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11814612	Peptides. 2002;23:7-11.	"Wang H, Ng TB."	"Isolation of cicadin, a novel and potent antifungal peptide from dried juvenile cicadas."
DRAMP03471	GFGCPGNQLKCNNHCKSISCRAGYCDAATLWLRCTCTDCNGKK	43	"Recombinant Crassostrea Gigas Defensin (Cg-Def; molluscs, animals)"	Q4GWV4	Not found	def	Crassostrea gigas (Pacific oyster)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Combine helix and strand structure	Not found	2B68 resolved by NMR.	Function: Has antibacterial activity (By similarity).	"Gram-positive bacteria: Micrococcus lysodeikticus (MIC=0.005-0.01 ?M), Staphylococcus aureus (MIC=1.25-2.5 ?M), Microbacterium maritypicum (MIC=0.5-1 ?M), Bacillus megaterium (MIC>20 ?M);##Gram-negative bacteria: Escherichia coli 363 (MIC=35-20 ?M), Vibrio alginolyticus (MIC>20 ?M), Salmonella typhimurium (MIC>20 ?M).##Fungi: Fusarium oxysporum (MIC=9-4.5 ?M), Botrytis cinerea (MIC>20 ?M), Penicillium crustosum (MIC>20 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid II	16246846	J Biol Chem. 2006 Jan 6;281(1):313-323.	"Gueguen Y, Herpin A, Aumelas A, Garnier J, Fievet J, Escoubas JM, Bulet P, Gonzalez M, Lelong C, Favrel P, Bach¨¨re E."	"Characterization of a defensin from the oyster Crassostrea gigas. Recombinant production, folding, solution structure, antimicrobial activities, and gene expression."
DRAMP03472	MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR	74	cgUbiquitin	No entry found	Not found	Not found	Crassostrea gigas (Pacific oyster)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Combine helix and strand structure	"According to the homology modeling, this peptide is composed of three secondary structural motifs including three ¦Á-helices and four ¦Â-strands separated by 7 loops regions."	None	"Function: cgUbiquitin shows broad potent antimicrobial activity against Gram-positive and -negative bacteria, without hemolytic activity."	"[Ref.22858580]Gram-positive bacteria: B. subtilis KCTC1021 (MIC=0.4 ?M), S. aureus RM4220 (MIC=4.7 ?M), S. iniae FP5229 (MIC=0.9 ?M);##Gram-negative bacteria: E. coli D31 (MIC=0.2 ?M), E. coli ML35p (MIC=1.4 ?M), P. aeruginosa KCTC2004 (MIC=0.6 ?M), S. flexneri KCTC2517 (MIC=0.7 ?M), S. sonnei KCTC2009 (MIC=1.2 ?M), A. hydrophila KCTC2358 (MIC=0.7 ?M), V. parahemolyticus KCCM41664 (MIC=1.1 ?M);##Yeast: C. albicans KCTC7965 (MIC=9.4 ?M)."	[Ref.22858580]Non-hemolytic against human red blood cells up to 100 ¦Ìg/mL	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22858580	Mol Immunol. 2013 Jan;53(1-2):88-98.	"Seo JK, Lee MJ, Go HJ, Kim GD, Jeong HD, Nam BH, Park NG."	"Purification and antimicrobial function of ubiquitin isolated from the gill of Pacific oyster, Crassostrea gigas."
DRAMP03474	VRPYLVAF	8	Pleurostatin (Fungus)	P84866	Not found	Not found	Pleurotus ostreatus (Oyster mushroom)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	20% growth inhibition Fusarium oxysporum (MIC=15.6 ?M).##45% growth inhibition Mycosphaerella arachidicola (MIC=15.6 ?M).##63% growth inhibition Physalospora piricola (MIC=15.6 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15941607	Peptides. 2005 Nov;26(11):2098-103. Epub 2005 Jun 6.	"Chu K.T, Xia L, Ng T.B. "	"Pleurostrin, an antifungal peptide from the oyster mushroom"
DRAMP03493	DKLIGSCVWGAVNYTSDCNGECKRRGYKGGHCGSFANVNCWCET	44	"Defensin heliomicin (Insects, animals)"	P81544	Not found	Not found	Heliothis virescens (Tobacco budworm moth)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	Not found	"1I2U,1I2V resolved by NMR. "	"Similar to plant defensin RsAFP2 (also in structure), it interacts with glucosylceramide isolated from the membranes of yeast and soybean but not humans (J Biol Chem 2004; 279: 3900-3905). Transgenic plants: expression of this peptide in tobacco improves resistance to pathogens (Montesinos E 2007 FEMS Microbiol Lett 270, 1-11)."	"Fungi: Neurospora crassa (MIC=0.1-0.2 ?M), Fusarium culmorum (MIC=0.2-0.4 ?M), Fusarium oxysporum (MIC=1.5-3 ?M), Nectria haematococca (MIC=0.4-0.8 ?M), Aspergillus fumigatus (MIC=6-12 ?M), Trichoderma viride (MIC=1.5-3 ?M), Candida albicans (MIC=2.5-5 ?M), Cryptococcus neoformans (MIC=2.5-5 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10092609##11580275	J Biol Chem. 1999 Apr 2;274(14):9320-9326.##Biochemistry. 2001 Oct 9;40(40):11995-2003.	"Lamberty M, Ades S, Uttenweiler-Joseph S, Brookhart G, Bushey D, Hoffmann JA, Bulet P.##Lamberty M, Caille A, Landon C, Tassin-Moindrot S, Hetru C, Bulet P, Vovelle F."	Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity.##Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities.
DRAMP03507	KWKIFKKIEKVGRNIRNGIIKAGPAVAVLGEAKAL	35	"Cecropin-B (Insects, animals)"	P01509	Belongs to the cecropin family	Not found	Antheraea pernyi (Chinese oak silkmoth)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.	"Gram-negative bacteria: Escherichia coli D21 (MIC=0.36 ?M), Escherichia coli D31 (MIC=0.30 ?M), Serratia marsescens (MIC=2.6 ?M), Serratia marsescens Strain 122 (MIC=12 ?M), Pseudomonas aeruginosa OT97 (MIC=2.9 ?M), Xenorhabdus nematophilus Xn21 (MIC=1.6 ?M);##Gram-positive bacteria: Bacillus subtilis Bsll (MIC=17 ?M), Bacillus megaterium Bmll (MIC=0.64 ?M), Bacillus thuringiensis Btll (MIC>88 ?M), Streptococcus fecalis Ds16 (MIC>88 ?M), Streptococcus fecalis AD-4 (MIC>88 ?M), Micrococcus luteus MI11 (MIC=0.29 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	6754375##2962676	Eur J Biochem. 1982 Sep;127(1):219-224.##Biomed Environ Mass Spectrom. 1987 Nov;14(11):669-673.	"Qu Z, Steiner H, Engstr?m A, Bennich H, Boman HG.##Craig AG, Engstr?m A, Bennich H, Kamensky I."	"Insect immunity: isolation and structure of cecropins B and D from pupae of the Chinese oak silk moth, Antheraea pernyi.##Plasma desorption mass spectrometry coupled with conventional peptide sequencing techniques."
DRAMP03513	KVNVNAIKKGGKAIGKGFKVISAASTAHDVYEHIKNRRH	39	"G. mellonella moricin-like peptide A (Gm-mlpA; Insects, animals; Predicted)"	A5JSU5	Not found	mor	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=10 ?M);##Gram-positive bacterium: Micrococcus luteus (MIC=10 ?M).##Fungi: Fusarium graminearum mycelia (MIC=70 ?M), F;##Graminearum spores (MIC=0.7 ?M), Fusarium oxysporum mycelia (MIC=7 ?M), F. oxysporum spores (MIC=10 ?M), Ascochyta rabiei spores (MIC=7 ?M), Leptosphaeria maculans spores (MIC=7 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18207081	Insect Biochem Mol Biol. 2008;38:201-212.	"Brown SE, Howard A, Kasprzak AB, Gordon KH, East PD."	The discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella.
DRAMP03514	GKIPVKAIKKGGQIIGKALRGINIASTAHDIISQFKPKKKKNH	43	"G. mellonella moricin-like peptide B (Gm-mlpB; Insects, animals; Predicted)"	A5JSU6	Not found	mor	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=100 ?M);##Gram-positive bacterium: Micrococcus luteus (MIC=100 ?M).##Fungi: Fusarium graminearum spores (MIC=10 ?M), F;##Graminearum mycelia (MIC=280 ?M), Fusarium oxysporum spores (MIC=100 ?M), F. oxysporum mycelia (MIC=280 ?M), Leptosphaeria maculans spores (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18207081	Insect Biochem Mol Biol. 2008;38:201-212.	"Brown SE, Howard A, Kasprzak AB, Gordon KH, East PD."	The discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella.
DRAMP03515	KVPIGAIKKGGKIIKKGLGVIGAAGTAHEVYSHVKNRH	38	"Moricin-like peptide C1 (Gm-mlpC1; Insects, animals; Predicted)"	A5JSU7	Not found	mor	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=10 ?M);##Gram-positive bacterium: Micrococcus luteus (MIC=100 ?M).##Fungi: Fusarium graminearum spores (MIC=1 ?M), Fusarium oxysporum spores (MIC=10 ?M), Ascochyta rabiei spores (MIC=100 ?M), Leptosphaeria maculans spores (MIC=6 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18207081	Insect Biochem Mol Biol. 2008;38:201-212.	"Brown SE, Howard A, Kasprzak AB, Gordon KH, East PD."	The discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella.
DRAMP03516	KVPIGAIKKGGKIIKKGLGVLGAAGTAHEVYNHVRNRQ	38	"Moricin-like peptide C2 (Gm-mlpC2; Insects, animals; Predicted)"	A5JSU8	Not found	mor	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=10 ?M);##Gram-positive bacterium: Micrococcus luteus (MIC=100 ?M).##Fungi: Fusarium graminearum spores (MIC=1 ?M), Fusarium oxysporum spores (MIC=10 ?M), Ascochyta rabiei spores (MIC=100 ?M), Leptosphaeria maculans spores (MIC=8 ?M), Fusarium graminearum mycelia (MIC=8 ?M), Fusarium oxysporum mycelia (MIC=8 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18207081	Insect Biochem Mol Biol. 2008;38:201-212.	"Brown SE, Howard A, Kasprzak AB, Gordon KH, East PD."	The discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella.
DRAMP03517	KVPIGAIKKGGKIIKKGLGVIGAAGTAHEVYSHVKNRQ	38	"Moricin-like peptide C3 (Gm-mlpC3; Insects, animals; Predicted)"	A5JSU9	Not found	mor	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=100 ?M);##Gram-positive bacterium: Micrococcus luteus (MIC=100 ?M).##Fungi: Fusarium graminearum spores (MIC=10 ?M), Fusarium oxysporum spores (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18207081	Insect Biochem Mol Biol. 2008;38:201-212.	"Brown SE, Howard A, Kasprzak AB, Gordon KH, East PD."	The discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella.
DRAMP03518	KVPVGAIKKGGKAIKTGLGVVGAAGTAHEVYSHIRNRH	38	"Moricin-like peptide C4/C5 (Gm-mlpC4/C5; Insects, animals; Predicted)"	A5JSV1	Not found	mor	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: Escherichia coli (MIC=100 ?M).##Fungi: Fusarium graminearum spores (MIC=100 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18207081	Insect Biochem Mol Biol. 2008;38:201-212.	"Brown SE, Howard A, Kasprzak AB, Gordon KH, East PD."	The discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella.
DRAMP03519	KGIGSALKKGGKIIKGGLGALGAIGTGQQVYEHVQNRQ	38	"Moricin-like peptide D (Gm-mlpD; Insects, animals; Predicted)"	A5JSV2	Not found	mor	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=10 ?M).##Fungi: Fusarium graminearum spores (MIC=10 ?M), Fusarium oxysporum spores (MIC=100 ?M), Ascochyta rabiei spores(MIC=100 ?M), Leptosphaeria maculans spores (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18207081	Insect Biochem Mol Biol. 2008;38:201-212.	"Brown SE, Howard A, Kasprzak AB, Gordon KH, East PD."	The discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella.
DRAMP03520	ENFFKEIERAGQRIRDAIISAAPAVETLAQAQKIIKGGD	39	"Cecropin-D-like peptide (Insects, animals)"	P85210	Not found	Not found	Galleria mellonella (greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Micrococcus luteus, Listeria monocytogenes, Sarcina Lutea, Escherichia coli D31(MIC=6.9-8.6 ?M), Aspergillus niger."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11995991##17194500	Acta Biochim Pol. 2001;48(4):1191-1195.##Peptides. 2007 Mar;28(3):533-546.	"Mak P, Chmiel D, Gacek GJ.##Cytrynska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T."	Antibacterial peptides of the moth Galleria mellonella.##Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.
DRAMP03521	DIQIPGIKKPTHRDIIIPNWNPNVRTQPWQRFGGNKS	37	"Proline-rich antimicrobial peptide 1 (Insects, animals)"	P85214	Not found	Not found	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Micrococcus luteus(MIC=55.0 ?M).##Fungi: Pichia pastoris (MIC=16.5 ?M), Zygosaccharomyces marxianus (MIC=16.5 ?M), Schizosaccharomyces pombe (MIC=11 ?M), candida wickerhamii (MIC=16.5 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11995991##17194500	Acta Biochim Pol. 2001;48(4):1191-1195.##Peptides. 2007 Mar;28(3):533-546.	"Mak P, Chmiel D, Gacek GJ.##Cytrynska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T."	Antibacterial peptides of the moth Galleria mellonella.##Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.
DRAMP03523	ETESTPDYLKNIQQQLEEYTKNFNTQVQNAFDSDKIKSEVNNFIESLGKILNTEKKEAPK	60	"Anionic antimicrobial peptide 2 (Insects, animals)"	P85216	Not found	Not found	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Micrococcus luteus(MIC=43.3-86.6 ?M), Listeria monocytogenes (MIC=86.6 ?M), Sarcina Lutea (MIC=86.6 ?M).##Fungi: Pichia pastoris (MIC=43.3-86.6 ?M), P. stipitis (MIC=43.3-86.6 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17194500	Peptides. 2007;28:533-546.	"Cytrynska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T."	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph
DRAMP03524	EADEPLWLYKGDNIERAPTTADHPILPSIIDDVKLDPNRRYA	42	"Lebocin-like anionic peptide 1 (Insects, animals)"	P85211	Not found	Not found	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Micrococcus luteus(MIC=22.7 ?M), Listeria monocytogenes (MIC=90.9 ?M).##Fungi: Aspergillus niger (MIC=90.9 ?M), Trichoderma harzianum (MIC=90.9 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17194500	Peptides. 2007;28:533-546.	"Cytrynska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T."	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.
DRAMP03527	DKLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFWNVNCWCEE	44	"Gm defensin-like peptide (Insects, animals)"	P85215	Not found	Not found	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Sarcina Lutea (MIC=1.9 ?M).##Fungi: Aspergillus niger (MIC=2.9 ?M), Candida albicans (MIC=2.9 ?M), C. fructus (MIC=2.9 ?M), Candida wickerhamii (MIC=2.9 ?M), Pichia pastoris (MIC=2.9 ?M), P. stiptis (MIC=2.9 ?M), Pachysolen tannophilus (MIC=2.9 ?M), Trichoderma harzianum (MIC=2.9 ?M), Zygosaccharomyces marxianus (MIC=2.9 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Has three disulfide bonds	L	No cytotoxicity information found	Not found	17194500	Peptides. 2007 Mar;28(3):533-546.	"Cytry??ska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T."	Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.
DRAMP03528	DTLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFLNVNCWCE	43	"Defensin (Galiomicin; Insects, animals)"	"P85213, Q6QR79"	Not found	Not found	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Aspergillus niger (MIC=2.1 ?M), Candida albicans (MIC=8.5 ?M), C. fructus (MIC=8.5 ?M), Fusarium oxysporum (MIC=16.9 ?M), Pichia pastoris (MIC=16.9 ?M), Pachysolen tannophilus (MIC=8.5 ?M), Trichoderma harzianum (MIC=4.2 ?M), Zygosaccharomyces Marxianus (MIC=8.5 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17194500##14728668	Peptides. 2007 Mar;28(3):533-546.##Insect Mol Biol 2004; 13: 65-72.	"Cytrynska M, Mak P, Zdybicka-Barabas A, Suder P, Jakubowicz T.##Lee Y.S, Yun E.K, Jang W.S, Kim I, Lee J.H, Park S.Y, Ryu K.S, Seo S.J, Kim C.H, Lee I.H."	"Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.##Purification, cDNA cloning and expression of an insect defensin from the great wax moth, Galleria mellonella."
DRAMP03539	EWEPVQNGGSSYYMVPRIWA	20	Antifungal protein (Psc-AFP)	No entry found	Not found	Not found	Cullen corylifolium	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Alternaria brassicae (MIC=10 ?M), Aspergillus niger (MIC=10 ?M), Fusarium oxysporum (MIC=10 ?M), Rhizoctonia cerealis (MIC=10 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16530884	Peptides. 27:1726-1731(2006)	"Yang X, Li J, Wang X, Fang W, Bidochka M.J, She R, Xiao Y, Pei Y."	"Psc-AFP, an antifungal protein with trypsin inhibitor activity from Psoralea corylifolia seeds"
DRAMP03540	CLAGRLDKQCTCRRSQPSRRSGHEVGRPSPHCGPSRQCGCHMD	43	"Human drosomycin-like defensin (DLD; Human, mammals, animals)"	No entry found	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antifungal"	Not found	Bridge 	Not found	None	"Function: This is the first indication of an endogenous human peptide with specific antifungal activity, which is probably central in the defense against infections with molds."	"Filamentous fungi: Aspergillus fumigatus (MIC=6.25 ?M), A. nidulans (MIC=6.25 ?M), A. ustus (MIC=12.5 ?M), Fusarium solani (MIC=25 ?M), F. oxysporum (MIC=6.25 ?M), R. oryzae (MIC=6.25 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Has three disulfide bonds	L	No cytotoxicity information found	Not found	18212107	Antimicrob Agents Chemother 2008; 52: 1407-1412.	Simon A et al Netea MG.	"Drosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity."
DRAMP03562	FLAKAVAKAAAKALAKAL	18	"P1 (Human, mammals, animals)"	No entry found	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Function: Presentes antifungal activity against Candida albicans. 	Yeast: Candida albicans (MIC=82 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22884922	Peptides. 2012 Oct;37(2):301-308.	"Amaral AC, Silva ON, Mundim NC, de Carvalho MJ, Migliolo L, Leite JR, Prates MV, Bocca AL, Franco OL, Felipe MS."	Predicting antimicrobial peptides from eukaryotic genomes: In silico strategies to develop antibiotics.
DRAMP03563	KAGLAFPVGRVHRLLRK	17	"P2 (Human, mammals, animals)"	No entry found	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Function: Presentes antifungal activity against Candida albicans. 	Yeast: Candida albicans (MIC=133 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22884922	Peptides. 2012 Oct;37(2):301-308.	"Amaral AC, Silva ON, Mundim NC, de Carvalho MJ, Migliolo L, Leite JR, Prates MV, Bocca AL, Franco OL, Felipe MS."	Predicting antimicrobial peptides from eukaryotic genomes: In silico strategies to develop antibiotics.
DRAMP03567	KRIVQRIKDFLRNLVPRTES	20	KR-20 (Derived from LL-37)	No entry found	Not found	Not found	Homo sapiens (Human sweat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix 	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus mprF (MIC=16 ?M), Staphylococcus aureus ATCC 25923 (MIC>64 ?M), Staphylococcus aureus (GAS) (MIC=4 ?M);##Gram-negative bacterium: Escherichia coli O29 (MIC>64 ?M).##Yeast: Candida albicans ATCC 14053 (MIC=10 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipopolysaccharide (LPS)-binding	14978112	J Immunol 2004; 172: 3070-3077.	"Murakami M, Lopez-Garcia B, Braff M, Dorschner RA, Gallo RL."	Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense.
DRAMP03568	RKSKEKIGKEFKRIVQRIKDFLRNLVPRTES	31	RK-31 (Derived from LL-37)	No entry found	Not found	Not found	Homo sapiens (Human sweat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix 	Not found	None	Function: Has hemolytic activity against human erythrocytes .	"[Ref.14978112]Gram-positive bacteria: Staphylococcus aureus mprF (MIC=8 ?M), Staphylococcus aureus ATCC 25923 (MIC=16 ?M), Group A Staphylococcus aureus (GAS) (MIC=8 ?M);##Gram-negative bacterium: Escherichia coli O29 (MIC=8 ?M);##Yeast: Candida albicans ATCC 14053 (MIC=4 ?M)."	[Ref.14978112]6% hemolytic activity at 44 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipopolysaccharide (LPS)-binding	14978112	J Immunol 2004; 172: 3070-3077.	"Murakami M, Lopez-Garcia B, Braff M, Dorschner RA, Gallo RL."	Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense.
DRAMP03569	KSKEKIGKEFKRIVQRIKDFLRNLVPRTES	30	KS-30 (Derived from LL-37)	No entry found	Not found	Not found	Homo sapiens (Human sweat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix 	Not found	None	Function:Has hemolytic activity against human erythrocytes.	"[Ref.14978112]Gram-positive bacteria: Staphylococcus aureus mprF (MIC=8 ?M), Staphylococcus aureus ATCC 25923 (MIC=16 ?M), Group A Staphylococcus aureus (GAS) (MIC=4 ?M);##Gram-negative bacterium: Escherichia coli O29 (MIC=8 ?M);##Yeast: Candida albicans ATCC 14053 (MIC=2 ?M)"	[Ref.14978112]23% hemolytic activity at 88 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipopolysaccharide (LPS)-binding	14978112	J Immunol 2004; 172: 3070-3077.	"Murakami M, Lopez-Garcia B, Braff M, Dorschner RA, Gallo RL."	Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense.
DRAMP03570	LLGDFFRKSKEKIGKEFKRIVQR	23	LL-23 (Derived from LL-37)	"P49913, Q71SN9"	Not found	Not found	Homo sapiens (Human sweat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix (1 helices; 19 residues)	"The Ser9 site splits the hydrophobic surface of the amphipathic helix into two domains, which explains its poor antimicrobial activity (active against only susceptible bacterial strains). "	2LMF resolved by NMR.	"Its structure, dynamics, and antimicrobial and immune modulating activities have been characterized (Biochemistry 2012)."	"Gram-negative bacterium: Escherichia coli DC2 (MIC=9 ?M);##Gram-positive bacteria: Staphylococcus aureus mprF (presence of carbonate) (MIC=3 ?M), S. aureu mprF (absence of carbonate) (MIC=24 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17012259##22185690	"FASEB J 2006; 20, 2068-2080.##Biochemistry. 2012 Jan 17;51(2):653-664. "	"Yamasaki K et al. Gallo RL.##Wang G, Elliott M, Cogen AL, Ezell EL, Gallo RL, Hancock RE."	"Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin.##Structure, dynamics, and antimicrobial and immune modulatory activities of human LL-23 and its single-residue variants mutated on the basis of homologous primate cathelicidins."
DRAMP03599	GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK	45	"Human beta-defensin 3 (BD-3, hBD-3; Hbd3; Beta-defensin 103; Human, mammals, animals)"	"P81534, Q8NFG6, Q9NPF6"	Belongs to the beta-defensin family	DEFB103A AND DEFB103	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Combine helix and strand structure	Contains three disulfide bonds and a short helical segment preceding a three-stranded antiparallel beta-sheet. 	1KJ6?resolved by NMR.	"Function: Exhibits antimicrobial activity against Gram-positive bacteria and the Gram-negative bacteria and the yeast C.albicans. Kills multiresistant S. aureus and vancomycin-resistant E. faecium. Has hemolytic activity.
Tissue specificity: Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
Induction: By bacterial infection and by IFNG/IFN-gamma.
PTM: Contains three disulfide bonds 11-40; 18-33; 23-41."	"[Ref.11085990]Gram-negative bacteria: Escherichia coli DSM1103 (MIC=9.4 ?g/ml), Klebsiella pneumoniae DSM681 (MIC=25 ?g/ml), Pseudomonas aeruginosa DSM1128 (MIC=18.75 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=4.7 ?g/ml), Streptococcus pneumoniae DSM11865 (MIC=4.7 ?g/ml)."	"[Ref.11085990] It has 9% hemolysis at 250 ?g/ml, 15% hemolysis at 500 ?g/ml against human erythrocytes."	Cyclic	Free	Free	"Disulfide bonds between Cys11 and Cys40,Cys18 and Cys33,Cys23 and Cys41."	L	No cytotoxicity information found	Not found	15625724##11085990	Biopolymers. 2005;80(1):34-49.##J Biol Chem. 2001 Feb 23;276(8):5707-5713.	"Schulz A, Kl¨¹ver E, Schulz-Maronde S, Adermann K.##Harder J, Bartels J, Christophers E, Schroder JM."	"Engineering disulfide bonds of the novel human beta-defensins hBD-27 and hBD-28: differences in disulfide formation and biological activity among human beta-defensins.##Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic."
DRAMP03642	GRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIR	39	"Chicken heterophil peptides 1 (Antimicrobial peptide CHP1; Birds, animals)"	P80389	Belongs to the beta-defensin family	Not found	Gallus gallus (Chicken)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge 	Not found	None	"Function: Bactericidal activity; inhibits S. aureus and E. coli.
PTM: Contains three disulfide bonds 6-28; 13-34; 18-35."	Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=2.7 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus (MIC=0.7 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys6 and Cys28,Cys13 and Cys34,Cys18 and Cys35."	L	No cytotoxicity information found	Not found	7964174	J Leukoc Biol. 1994 Nov;56(5):661-665.	"Evans EW, Beach GG, Wunderlich J, Harmon BG."	Isolation of antimicrobial peptides from avian heterophils.
DRAMP01376	GFMDTAKNAAKNVAVTLLDNLKCKITKAC	29	"Odorranain-F1 (OdF1; Frogs, amphibians, animals)"	A6MBL3	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Odorranain-F1 adopts 55% 	None	Function: Odorranain-F1 exhibites antimicrobial activities against the tested microbes including Gram-positive and Gram-negative bacteria and fungi. Also has hemolytic activity against rabbiit red cell.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=4.20 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=2.10 ¦Ìg/ml), Bacillus subtilis (MIC=8.40 ¦Ìg/ml).##Yeast: Candida albicans (MIC=1.05 ¦Ìg/ml)."	"[Ref.17272268] RCH=15.4 ¡À 3.5% against rabbit red blood cells at 50 ¦Ìg/ml. RCH, red cell hemolysis."	Cyclic	Free	Cyclization (Cys23 and Cys29)	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01378	GIFGKILGVGKKVLCGLSGVC	21	"Odorranain-H1 (OdH1; Frogs, amphibians, animals)"	A6MBN4	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Odorranain-H1 adopts 50.3 ¦Â-sheet structure in water solution.	None	Function: Odorranain-H1 exhibites antimicrobial activities against Gram-positive and Gram-negative bacteria and fungi. Also has hemolytic activity against rabbit red cell.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=23.60 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=5.90 ¦Ìg/ml), Bacillus subtilis (MIC=5.90 ¦Ìg/ml).##Yeast: Candida albicans (MIC=11.80 ¦Ìg/ml)."	"[Ref.17272268] RCH=21.6 ¡À 7.3% against rabbit red blood cells. RCH, red cell hemolysis."	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01386	VIPFVASVAAEMMQHVYCAASKKC	24	"Odorranain-P1a (OdP1a; Brevinin-1HS1; Brevinin-1-OA2; Frogs, amphibians, animals)"	"A6MBQ8, A6MBQ6"	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	Function: Odorranain-P1a exhibites antimicrobial activities against all of the tested microbes including Gram-positive and Gram-negative bacteria and fungi. Also has hemolytic activity against rabbit red cell. 	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=3.50 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.50 ¦Ìg/ml), Bacillus subtilis (MIC=1.75 ¦Ìg/ml).##Yeast: Candida albicans (MIC=1.75 ¦Ìg/ml)."	"[Ref.17272268] RCH=11.2 ¡À 2.9% against rabbit red blood cells. RCH, red cell hemolysis."	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP03682	FLPIIAKLLGGLL	13	"Vespid chemotactic peptide 5e (VCP 5e; Insects, animals)"	P0C1M1	Belongs to the MCD family (Crabrolin subfamily)	Not found	Vespa magnifica 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Mast cell degranulating peptide (By similarity). Has little hemolytic activity. Shows antimicrobial activity against the Gram-negative bacteria and the Gram-positive bacteria. Also has antifungal activity.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation (By similarity)."	[Ref.16330062]Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=30 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=5 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=25 ?g/ml).	[Ref.16330062]Little hemolytic activity up to 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16330062	Toxicon. 2006 Feb;47(2):249-53.	"Xu X, Li J, Lu Q, Yang H, Zhang Y, Lai R."	Two families of antimicrobial peptides from wasp (Vespa magnifica) venom.
DRAMP03683	FLIIRRPIVLGLL	13	"Vespid chemotactic peptide 5g (VCP 5g; Insects, animals)"	P0C1M3	Belongs to the MCD family (Crabrolin subfamily)	Not found	Vespa magnifica 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Mast cell degranulating peptide (By similarity). Has little hemolytic activity. Shows antimicrobial activity against the Gram-negative bacteria and the Gram-positive bacteria. Also has antifungal activity.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation (By similarity)."	[Ref.16330062]Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=30 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=10 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=12.5 ?g/ml).	[Ref.16330062]Little hemolytic activity up to 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16330062	Toxicon. 2006 Feb;47(2):249-53.	"Xu X, Li J, Lu Q, Yang H, Zhang Y, Lai R."	Two families of antimicrobial peptides from wasp (Vespa magnifica) venom.
DRAMP03684	FLPIPRPILLGLL	13	"Vespid chemotactic peptide 5f (VCP 5f; Insects, animals)"	P0C1M2	Belongs to the MCD family (Crabrolin subfamily)	Not found	Vespa magnifica 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Mast cell degranulating peptide (By similarity). Has little hemolytic activity. Shows antimicrobial activity against the Gram-negative bacteria and the Gram-positive bacteria. Also has antifungal activity.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation (By similarity)."	[Ref.16330062]Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=30 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=5 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=25 ?g/ml).	[Ref.16330062]Little hemolytic activity up to 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16330062	Toxicon. 2006 Feb;47(2):249-53. 	"Xu X, Li J, Lu Q, Yang H, Zhang Y, Lai R."	Two families of antimicrobial peptides from wasp (Vespa magnifica) venom.
DRAMP03688	FLGMIPGLIGGLISAFK	17	"TsAP-2 (T. serrulatus antimicrobial peptide 2; scorpions, arachnids, invertebrates, animals)"	No entry found	Not found	Not found	Tityus serrulatus (Brazilian yellow scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal, Anti-cancer"	Not found	Not found	Not found	None	"Function: TsAP-2 was of high potency against the Gram-positive bacterium, Staphylococcus aureus and the yeast Candida albicans."	Gram-positive bacterium: Staphylococcus aureus (MIC=5 ?M).##Yeast: Candida albicans (MIC=10 ?M). 	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23770440	Biochimie. 2013 Jun 14. pii: S0300-9084(13)00164-8.	"Guo X, Ma C, Du Q, Wei R, Wang L, Zhou M, Chen T, Shaw C."	"Two peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their antimicrobial and anticancer activities."
DRAMP03706	FLFSLIPHAIGGLISAFK	18	"Antimicrobial peptide 1 (AamAP1; Arthropods, animals)"	G8YYA5	Not found	ap1	Androctonus amoreuxi (African fattail scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antibacterial and antifungal activity. Causes hemolysis on horse erythrocytes.
Tissue specificity: Expressed by the venom gland.
PTM: C-termianal amidation."	Gram-positive bacterium: Staphylococcus aureus (MIC=20 ?M);##Gram-negative bacterium: Escherichia coli (MIC=150 ?M).##Yeast: Candida albicans (MIC=64 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	22484288	Peptides. 2012 Jun;35(2):291-299.	"Almaaytah A, Zhou M, Wang L, Chen T, Walker B, Shaw C."	"Antimicrobial/cytolytic peptides from the venom of the North African scorpion, Androctonus amoreuxi: biochemical and functional characterization of natural peptides and a single site-substituted analog."
DRAMP03707	FPFSLIPHAIGGLISAIK	18	"Antimicrobial peptide 2 (AamAP2; Arthropods, animals)"	G8YYA6	Not found	ap2	Androctonus amoreuxi (African fattail scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antibacterial and antifungal activity. Causes hemolysis on horse erythrocytes.
Tissue specificity: Expressed by the venom gland.
PTM: C-termianal amidation."	Gram-positive bacterium: Staphylococcus aureus (MIC=48 ?M);##Gram-negative bacterium: Escherichia coli (MIC=120 ?M).##Yeast: Candida albicans (MIC=64 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	22484288	Peptides. 2012 Jun;35(2):291-299.	"Almaaytah A, Zhou M, Wang L, Chen T, Walker B, Shaw C."	"Antimicrobial/cytolytic peptides from the venom of the North African scorpion, Androctonus amoreuxi: biochemical and functional characterization of natural peptides and a single site-substituted analog."
DRAMP01392	GLLSGTSVRGSI	12	"Odorranain-V1 (OdV1; Frogs, amphibians, animals)"	A6MBS7	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	Function: Odorranain-V1 exhibites moderate antimicrobial activities against all of the tested microbes. Also has hemolytic activity against rabbit red cells	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=36.00 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=18.00 ¦Ìg/ml), Bacillus subtilis (MIC=18.00 ¦Ìg/ml).##Yeast: Candida albicans (MIC=9.00 ¦Ìg/ml)."	"[Ref.17272268] RCH=23.9 ¡À 4.7% against rabbit red blood cells. RCH, red cell hemolysis."	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01393	GLFGKSSVWGRKYYVDLAGCAKA	23	"Odorranain-W1 (OdW1; Frogs, amphibians, animals)"	A6MBS8	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	Function: Odorranain-W1 has hemolytic activity against rabbit red cell.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=12.60 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=6.30 ¦Ìg/ml), Bacillus subtilis (MIC=6.30 ¦Ìg/ml).##Yeast: Candida albicans (MIC=3.15 ¦Ìg/ml)."	"[Ref.17272268] RCH=17.6 ¡À 2.2% against rabbit red blood cells. RCH, red cell hemolysis."	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP03729	KWFNEKSIQNKIDEKIGKNFLGGMAKAVVHKLAKNEFMCVANVDMTKSCDTHCQKASGEKGYCHGTKCKCGVPLSY	76	"Opiscorpine-1 (Arthropods, animals)"	"Q5WR03, Q5WQZ8"	Belongs to the long chain scorpion toxin family (Class 3 subfamily)	Not found	Opistophthalmus carinatus (African yellow leg scorpion)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: The short amino-terminal segment of opiscorpine 1 (residues 1¨C35), named Jan-f3, has antimicrobial activity against fungi and the Gram-negative bacteria.
Tissue specificity: Expressed by the venom gland.
PTM: Contains three disulfide bonds (By similarity)."	"Fungi: Fusarium culmorum IMI180420 (IC50=8.8 ?M), Fusarium oxysporum MUCL39789 (IC50=10.04 ?M).##Gram-negative bacterium: Escherichia coli JM109 (MIC=12 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15241551	Cell Mol Life Sci. 2004 Jul;61(14):1751-1763.	"Zhu S, Tytgat J."	"The scorpine family of defensins: gene structure, alternative polyadenylation and fold recognition."
DRAMP03734	FKLGSFLKKAWKSKLAKKLRAKGKEMLKDYAKGLLEGGSEEVPGQ	45	"Parabutoporin (PP; Non-disulfide-bridged peptide 3.2, NDBP-3.2; Arthropods, animals)"	P83312	Belongs to the scorpion BPP family	Not found	Parabuthus schlechteri (Scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: At high concentrations, acts as pore former in cellular membranes and causes the leakage of the cells. At submicromolar concentrations, degranulates granulocytes and has hemolytic activity against human red blood cells. Also strongly inhibits the production of superoxide anions. Has a strong antibacterial activity against Gram-negative bacteria but is less active against Gram-positive bacteria. Also has antifungal activity. Induces reversible G-protein dependent Ca2+ release from intracellular stores and increase Ca2+ influx in HL-60 cells. Induces the activation of the Rac pathway in granulocytes. Synergistically enhances the excitatory effects of short and long chain ion-channel-specific neurotoxins by interaction with the neuronal membranes.
Tissue specificity: Expressed by the venom gland.
NOTE: residue 11, 44, 55 are uncertainty."	"[Ref.12354111]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3.1 ?M), Escherichia coli DH5a (MIC=3.1 ?M), Pseudomonas aeruginosa ATCC 257853 (MIC=6.3 ?M), Klebsiella pneumoniae ATCC 13833 (MIC=1.6 ?M), Salmonella choleraesuis ATCC 13311 (MIC=3.1 ?M), Haemophilus influenzae ATCC 19418 (MIC=3.1 ?M);##Gram-positive bacteria: Bacillus subtilis ATCC 6051 (MIC=6.3 ?M), Listeria monocytogenes NCTC 11994 (MIC=6.3 ?M), Micrococcus luteus ATCC 9341 (MIC=25 ?M);##Fungi: Neurospora crassa (MIC=2.5 ?M), Botrytis cinerea (MIC=3.5 ?M), Fusarium culmorum (MIC=0.3 ?M), Saccharomyces cerevisiae (MIC=2 ?M)."	[Ref.12354111]50% hemolysis is induced by about 38 ?M against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	12354111##12457879##14575699##15245865	Eur J Biochem. 2002 Oct;269(19):4799-4810.##Toxicon. 2002 Dec;40(12):1679-1683.##iochem Biophys Res Commun. 2003 Nov 7;311(1):90-97.##Peptides. 2004 Jul;25(7):1079-1084.	"Moerman L, Bosteels S, Noppe W, Willems J, Clynen E, Schoofs L, Thevissen K, Tytgat J, Van Eldere J, Van Der Walt J, Verdonck F.Willems J, Noppe W, Moerman L, van der Walt J, Verdonck F.##Moerman L, Verdonck F, Willems J, Tytgat J, Bosteels S.##Willems J, Moerman L, Bosteels S, Bruyneel E, Ryniers F, Verdonck F."	"Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa.##Cationic peptides from scorpion venom can stimulate and inhibit polymorphonuclear granulocytes.##Antimicrobial peptides from scorpion venom induce Ca(2+) signaling in HL-60 cells.##Parabutoporin--an antibiotic peptide from scorpion venom--can both induce activation and inhibition of granulocyte cell functions."
DRAMP03735	GKVWDWIKSTAKKLWNSEPVKELKNTALNAAKNLVAEKIGATPS	44	"Opistoporin-1 (OP1; Non-disulfide-bridged peptide 3.5; Opistoporin-3, OP3; Arthropods, animals)"	"P83313, Q5VJS8, Q5VJT0"	Belongs to the antimicrobial peptide scorpion family	Not found	Opistophthalmus carinatus (African yellow leg scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: At high concentrations, acts as pore former in cellular membranes and causes the leakage of the cells. At submicromolar concentrations, degranulates granulocytes and has hemolytic activity against human red blood cells. Also strongly inhibits the production of superoxide anions. Has a strong antibacterial activity against Gram-negative bacteria but is less active against Gram-positive bacteria. Also has antifungal activity.
Tissue specificity: Expressed by the venom gland."	"[Ref.12354111]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=12.5 ?M), Escherichia coli DH5a (MIC=6.3 ?M), Serratia marcescens ATCC 133880 (MIC=50 ?M), Pseudomonas aeruginosa ATCC 257853 (MIC=12.5 ?M), Klebsiella pneumoniae ATCC 13833 (MIC=6.3 ?M), Salmonella choleraesuis ATCC 13311 (MIC=25 ?M), Haemophilus influenzae ATCC 19418 (MIC=1.6 ?M);##Gram-positive bacteria: Bacillus subtilis ATCC 6051 (MIC=12.5 ?M), Bacillus subtilis IP 5832 (MIC=12.5 ?M), Listeria monocytogenes NCTC 11994 (MIC=12.5 ?M), Micrococcus luteus ATCC 9341 (MIC>50 ?M), Enterococcus faecalis ATCC 19433 (MIC=12.5 ?M), Staphylococcus aureus ATCC 292136.3 (MIC>50 ?M), Streptococcus pneumoniae ATCC 33400 (MIC=12.5 ?M), Nocardia asteroides ATCC 3308 (MIC>50 ?M);##Fungi: Neurospora crassa (IC50=0.8 ?M), Botrytis cinerea (IC50=3.1 ?M), Fusarium culmorum (IC50=0.8 ?M), Saccharomyces cerevisiae (IC50=2 ?M)."	"[Ref.12354111]10% hemolytic activity at 10 ?M, 30% hemolytic activity at 100 ?M against human red blood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	12354111##12457879##14575699	Eur J Biochem. 2002 Oct;269(19):4799-4810.##Toxicon. 2002 Dec;40(12):1679-1683.##iochem Biophys Res Commun. 2003 Nov 7;311(1):90-97.	"Moerman L, Bosteels S, Noppe W, Willems J, Clynen E, Schoofs L, Thevissen K, Tytgat J, Van Eldere J, Van Der Walt J, Verdonck F.Willems J, Noppe W, Moerman L, van der Walt J, Verdonck F.##Moerman L, Verdonck F, Willems J, Tytgat J, Bosteels S."	"Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa.##Cationic peptides from scorpion venom can stimulate and inhibit polymorphonuclear granulocytes.##Antimicrobial peptides from scorpion venom induce Ca(2+) signaling in HL-60 cells."
DRAMP02828	GLFRRLRDSIRRGQQKILEKARRIGERIKDIFRG	34	"BMAP-34 (BMAP 34, bovine cathelicidin, cattle, ruminant, mammals, animals)"	P56425	Belongs to the cathelicidin family.	CATHL7	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Antibacterial activity against the Gram-negative bacteria and Gram-positive bacteria. 
Tissue specificity: Expressed in bone marrow myeloid cells, spleen and testis."	"[Ref.9795251] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=3 ¦ÌM), Staphylococcus aureus Cowan 1 (MIC=3 ¦ÌM), Staphylococcus aureus (MRSA, clinical isolate) (MIC=6 ¦ÌM), Staphylococcus epidermidis ATCC 12228 (MIC=1.5 ¦ÌM), Bacillus megaterium Bm 11 (MIC=3 ¦ÌM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=1.5 ¦ÌM), Escherichia coli ML-35 (MIC=1.5 ¦ÌM), Escherichia coli D21 (MIC=1.5 ¦ÌM), Escherichia coli D22 (MIC=1.5 ¦ÌM), Salmonella typhimurium ATCC 14028 (MIC=3 ¦ÌM), Salmonella enteritidis (clinical isolate) (MIC=3 ¦ÌM), Serratia marcescens ATCC 8100 (MIC=1.5 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC¡Ý48 ¦ÌM);##Fungus: Candida albicans (clinical isolate) (MIC>96 ¦ÌM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9409740##9795251	FEBS Lett. 1997 Nov 17;417(3):311-5.##Biochim Biophys Acta. 1998 Oct 23;1425(2):361-368.	"Scocchi M, Wang S, Zanetti M.##Gennaro R, Scocchi M, Merluzzi L, Zanetti M."	Structural organization of the bovine cathelicidin gene family and identification of a novel member.##Biological characterization of a novel mammalian antimicrobial peptide.
DRAMP03748	FRFGSFLKKVWKSKLAKKLRSKGKQLLKDYANKVLNGPEEEAAAPAE	47	"Bradykinin-potentiating peptide BmK3 (Bpp BmK3; NDBP-3.3; Arthropods, animals)"	Q9Y0X4	Belongs to the scorpion BPP family	Not found	Mesobuthus martensii (Manchurian scorpion) (Buthus martensii)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Alpha helix (predict)	"The secondary structure prediction for BmKbpp reveals that BmKbpp is composed of an ¦Á-helical structure from amino residues 3-35, followed by a coil-coiled region of three residues (NGP), and ended with an ¦Á-helical region of 9 residues (ref.2)."	None	"Function: Amphipathic peptide that shows bradykinin potentiating activity and antimicrobial activities against bacteria and fungi. Has higher antibacterial activities against Gram-negative than against Gram-positive bacteria. Also inhibits NADPH oxidase-dependent superoxide production (IC50 is 0.4 ?M on granulocytes stimulated with PMA, IC50 is 0.51 ?M on HL-60 cells undifferentiated and IC50 is 0.53 ?M on HL-60 cells treated with DMSO). The C-terminal peptide shows a higher bradykinin potentiating activity than the complete peptide.
Tissue specificity: Expressed by the venom gland.
Miscellaneous: Shows hemolytic activity. Shows a alpha-helical structure. The genomic DNA coding for this protein is not a continuous sequence in the genome. The transcript of this protein may be generated by trans-splicing, by which exons from two independently transcribed pre-mRNAs are joined to form a single mature transcript."	"[Ref.22115565]Gram-negative bacteria: Escherichia coli DH 5-¦Á (MIC=2.3 ?M), Haemophilus in?uenzae ATCC 31517 (MIC=3.2 ?M), Klebsiella pneumoniae ATCC 13882 (MIC=2.8 ?M), Salmonella enterica ATCC 8090 (MIC=2.3 ?M), Pseudomonas aeruginosa ATCC 9229 (MIC=4.7 ?M), Serratia marcescens ATCC 13880 (MIC=68.2 ?M);##Gram-positive bacteria: Bacillus subtilis ATCC 6051 (MIC=24.4 ?M), Listeria monocytogenes ATCC 35152 (MIC=5.7 ?M), Micrococcus luteus ATCC 9341 (MIC=20.3 ?M), Enterococcus faecalis ATCC 14508 (MIC=57.1 ?M), Nocardia asteroides ATCC 3308 (MIC>70 ?M), Staphylococcus aureus ATCC 14458 (MIC>70 ?M);##Fungi: Neurospora crassa FGSC 2489 (IC50=2 ?M), Botrytis cinerea ATCC 28387 (IC50=3.1 ?M), Fusarium culmorum ATCC 32973 (IC50=0.2 ?M)."	"[Ref.22115565]3.5% hemolytic activity at 6 ¦ÌM, 11.2% hemolytic activity at 10 ¦ÌM, 22.5% hemolytic activity at 30 ¦ÌM, 33.9% hemolytic activity at 50 ¦ÌM against human red blood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10868911##22115565	IUBMB Life. 2000 Mar;49(3):207-210.##Peptides. 2012 Jan;33(1):44-51.	"Zeng XC, Li WX, Peng F, Zhu ZH.##Zeng XC, Wang S, Nie Y, Zhang L, Luo X."	"Cloning and characterization of a novel cDNA sequence encoding the precursor of a novel venom peptide (BmKbpp) related to a bradykinin-potentiating peptide from Chinese scorpion Buthus martensii Karsch.##Characterization of BmKbpp, a multifunctional peptide from the Chinese scorpion Mesobuthus martensii Karsch: gaining insight into a new mechanism for the functional diversification of scorpion venom peptides."
DRAMP03750	IFGAIAGLLKNIF	13	"Venom antimicrobial peptide-6 (Meucin-13; NDBP-5; Arthropods, animals)"	"E4VP07, E4VP35"	Belongs to the scorpion NDBP 5 family	Not found	Mesobuthus eupeus (Lesser Asian scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Amphipathic peptide that exhibits extensive cytolytic activities against both prokaryotic and eukaryotic cells. Is more potent against Gram-positive bacteria (lethal concentration (LC=0.25-2.9 ?M) than against Gram-negative bacteria (LC=6.2->50 ?M), and fungi (LC=14.1->50 ?M). Shows hemolytic activity against rabbit erythrocytes and cytolysis against rat dorsal root ganglions. In vivo, intravenous injection into mice tail provokes uncomfortable symptoms with a death rate of 12.5%.
Tissue specificity: Expressed by the venom gland."	"[Ref.19088182]Gram-positive bacteria: Bacillus sp. DM-1 (MIC=2 ?M), Micrococcus luteus (MIC=2.9 ?M), Bacillus megaterium (MIC=0.25 ?M);##Gram-negative bacteria: Agrobacterium tumefaciens (MIC=11.8 ?M), Escherichia coli (MIC=7.90 ?M), Shewanella oneidensis (MIC=6.20 ?M), Stenotrophomonus sp. YC-1 (MIC=6.20 ?M);##Fungi: Beauveria spp. (MIC=14.1 ?M), Neurospora crassa (MIC=18.3 ?M), Candida albicans (MIC=42.8 ?M), Saccharomyces cerevisiae (MIC=18.3 ?M)."	"[Ref.19088182]37.7% hemolytic activity at 6.25 M, 59.2% hemolytic activity at 12.5 M against rabbit red blood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	19088182	FASEB J. 2009 Apr;23(4):1230-1245.	"Gao B, Sherman P, Luo L, Bowie J, Zhu S."	Structural and functional characterization of two genetically related meucin peptides highlights evolutionary divergence and convergence in antimicrobial peptides.
DRAMP03751	FFGHLFKLATKIIPSLFQ	18	"Venom antimicrobial peptide-9 (Meucin-18; NDBP-5; Arthropods, animals)"	E4VP50	Belongs to the ponericin-W family	Not found	Mesobuthus eupeus (Lesser Asian scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Amphipathic peptide that exhibits extensive cytolytic activities against both prokaryotic and eukaryotic cells. Is more potent against Gram-positive bacteria (lethal concentration (LC=1.5-10.9 ?M) than against Gram-negative bacteria (LC=6.2-50 ?M), and fungi (LC=25.1-8.3 ?M). Is lethal to the fungus Beauveria sp (LC=1.9 ?M), a highly lethal pathogenic fungus to insects and resistant to many AMPs. Shows hemolytic activity against rabbit erythrocytes and cytolysis against rat dorsal root ganglions. In vivo, intravenous injection into mice tail provokes uncomfortable symptoms with a death rate of 12.5%.
Tissue specificity: Expressed by the venom gland."	"[Ref.19088182]Gram-positive bacteria: Bacillus sp. DM-1 (MIC=0.60 ?M), Micrococcus luteus (MIC=0.60 ?M), Bacillus megaterium (MIC=0.25 ?M);##Gram-negative bacteria: Agrobacterium tumefaciens (MIC=6.00 ?M), Escherichia coli (MIC=2.40 ?M), Shewanella oneidensis (MIC=1.50 ?M), Stenotrophomonus sp. YC-1(MIC=2.60 ?M), Salmonella typhimurium (MIC=10.9 ?M);##Fungi: Beauveria spp.(MIC=1.9 ?M), Neurospora crassa (MIC=5.2 ?M), Candida albicans (MIC=25.1 ?M), Saccharomyces cerevisiae (MIC=25.1 ?M), Aspergillus fumigatus (MIC=8.3 ?M), Geotrichum candidum (MIC=3.5 ?M)."	"[Ref.19088182]74% hemolytic activity at 6.25 M, 100% hemolytic activity at 12.5 M against rabbit red blood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	19088182	FASEB J. 2009 Apr;23(4):1230-1245.	"Gao B, Sherman P, Luo L, Bowie J, Zhu S."	Structural and functional characterization of two genetically related meucin peptides highlights evolutionary divergence and convergence in antimicrobial peptides.
DRAMP03831	GLWNSIKIAGKKLFVNVLDKIRCKVAGGC	29	Palustrin-2ISb-des-C7	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=6.3 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=1.6 ?M), S. aureus (MRSA) (MIC=12.5 ?M).##Yeast: Candida albicans (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization(Cys23 and Cys29).	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	21911019	Peptides. 2011 Oct;32(10):2052-2057.	"Iwakoshi-Ukena E, Okada G, Okimoto A, Fujii T, Sumida M, Ukena K."	Identification and structure-activity relationship of an antimicrobial peptide of the palustrin-4 family isolated from the skin of the endangered frog Odorrana ishikawae.
DRAMP03832	GLWDSIKIAGKKLFVNVLDKIRCKVAGGC	29	Palustrin-2ISb-des-C7-4D	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=12.5 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.1 ?M), S. aureus (MRSA) (MIC=12.5 ?M);##yeast Candida albicans (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization(Cys23 and Cys29).	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	21911019	Peptides. 2011 Oct;32(10):2052-2057.	"Iwakoshi-Ukena E, Okada G, Okimoto A, Fujii T, Sumida M, Ukena K."	Identification and structure-activity relationship of an antimicrobial peptide of the palustrin-5 family isolated from the skin of the endangered frog Odorrana ishikawae.
DRAMP03833	GLWNSIKIAGKNLFVNVLDKIRCKVAGGC	29	Palustrin-2ISb-des-C7-12N	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=12.5 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.1 ?M), S. aureus (MRSA) (MIC=12.5 ?M);##yeast Candida albicans (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization(Cys23 and Cys29).	Disulfide bond between Cys23 and Cys29.	L	No cytotoxicity information found	Not found	21911019	Peptides. 2011 Oct;32(10):2052-2057.	"Iwakoshi-Ukena E, Okada G, Okimoto A, Fujii T, Sumida M, Ukena K."	Identification and structure-activity relationship of an antimicrobial peptide of the palustrin-6 family isolated from the skin of the endangered frog Odorrana ishikawae.
DRAMP03834	GLWNSIKIAGKKLFVNVLDKIRSKVAGGS	29	"Palustrin-2ISb-des-C7-23,29S"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli (MIC=3.1 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC=6.3 ?M), S. aureus (MRSA) (MIC=25 ?M);##yeast Candida albicans (MIC=100 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21911019	Peptides. 2011 Oct;32(10):2052-2057.	"Iwakoshi-Ukena E, Okada G, Okimoto A, Fujii T, Sumida M, Ukena K."	Identification and structure-activity relationship of an antimicrobial peptide of the palustrin-7 family isolated from the skin of the endangered frog Odorrana ishikawae.
DRAMP03835	GKKLFVNVLDKIRCKVAGGC	20	Palustrin-2ISb-des-C7-des-N9	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	Yeast: Candida albicans (MIC=100 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization(Cys16 and Cys20).	Disulfide bond between Cys16 and Cys20.	L	No cytotoxicity information found	Not found	21911019	Peptides. 2011 Oct;32(10):2052-2057.	"Iwakoshi-Ukena E, Okada G, Okimoto A, Fujii T, Sumida M, Ukena K."	Identification and structure-activity relationship of an antimicrobial peptide of the palustrin-8 family isolated from the skin of the endangered frog Odorrana ishikawae.
DRAMP03852	GLARIVVIRVAR	12	G1 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=125 ?g/ml), Escherichia coli (MIC=16 ?g/ml), Salmonella typhimurium (MIC=63 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=63 ?g/ml), Staphylococcus epidermidis (MIC=16 ?g/ml), Enterococcus faecalis (MIC=31 ?g/ml).##Yeast: Candida albicans (MIC=125 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03853	RGARIVVIRVAR	12	G2 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=31 ?g/ml), Escherichia coli (MIC=8 ?g/ml), Salmonella typhimurium (MIC=31 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=31 ?g/ml), Staphylococcus epidermidis (MIC=16 ?g/ml), Enterococcus faecalis (MIC=31 ?g/ml).##Yeast: Candida albicans (MIC=16 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03854	RRARIVVIRVAR	12	R2 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=8 ?g/ml), Escherichia coli (MIC=4 ?g/ml), Salmonella typhimurium (MIC=8 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=16 ?g/ml), Staphylococcus epidermidis (MIC=2 ?g/ml), Enterococcus faecalis (MIC=16 ?g/ml).##Yeast: Candida albicans (MIC=8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03855	RLRRIVVIRVAR	12	R3 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=8 ?g/ml), Escherichia coli (MIC=4 ?g/ml), Salmonella typhimurium (MIC=8 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=8 ?g/ml), Staphylococcus epidermidis (MIC=2 ?g/ml), Enterococcus faecalis (MIC=8 ?g/ml).##Yeast: Candida albicans (MIC=16 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03856	RLWRIVVIRVAR	12	W3 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=8 ?g/ml), Escherichia coli (MIC=2 ?g/ml), Salmonella typhimurium (MIC=8 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=2 ?g/ml), Staphylococcus epidermidis (MIC=0.5 ?g/ml), Enterococcus faecalis (MIC=2 ?g/ml).##Yeast: Candida albicans (MIC=8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03857	RLARRVVIRVAR	12	R5 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=63 ?g/ml), Escherichia coli (MIC=16 ?g/ml), Salmonella typhimurium (MIC=31 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=63 ?g/ml), Staphylococcus epidermidis (MIC=16 ?g/ml), Enterococcus faecalis (MIC=125 ?g/ml).##Yeast: Candida albicans (MIC=125 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03858	RLARIVKIRVAR	12	K7 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=31 ?g/ml), Escherichia coli (MIC=16 ?g/ml), Salmonella typhimurium (MIC=63 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=125 ?g/ml), Staphylococcus epidermidis (MIC=31 ?g/ml), Enterococcus faecalis (MIC=125 ?g/ml).##Yeast: Candida albicans (MIC=31 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03859	RLARIVVIRWAR	12	W10 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=16 ?g/ml), Escherichia coli (MIC=4 ?g/ml), Salmonella typhimurium (MIC=8 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=8 ?g/ml), Staphylococcus epidermidis (MIC=2 ?g/ml), Enterococcus faecalis (MIC=4 ?g/ml).##Yeast: Candida albicans (MIC=8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03860	RLARIVVIRVRR	12	R11 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=16 ?g/ml), Escherichia coli (MIC=8 ?g/ml), Salmonella typhimurium (MIC=8 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=8 ?g/ml), Staphylococcus epidermidis (MIC=2 ?g/ml), Enterococcus faecalis (MIC=8 ?g/ml).##Yeast: Candida albicans (MIC=8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03861	RLARIVVIRVAG	12	G12 (Bac2A variant through single amino acid substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=63 ?g/ml), Escherichia coli (MIC=16 ?g/ml), Salmonella typhimurium (MIC=63 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=63 ?g/ml), Staphylococcus epidermidis (MIC=31 ?g/ml), Enterococcus faecalis (MIC=31 ?g/ml).##Yeast: Candida albicans (MIC=63 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03862	RLRRIVVIRVRR	12	Sub2 (Bac2A variant through two amino acids substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=8 ?g/ml), Escherichia coli (MIC=2 ?g/ml), Salmonella typhimurium (MIC=8 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=8 ?g/ml), Staphylococcus epidermidis (MIC=2 ?g/ml), Enterococcus faecalis (MIC=4 ?g/ml).##Yeast: Candida albicans (MIC=31 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03863	RRWRIVVIRVRR	12	Sub3 (Bac2A variant through three amino acids substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=2 ?g/ml), Escherichia coli (MIC=2.5 ?g/ml), Salmonella typhimurium (MIC=4 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=2 ?g/ml), Staphylococcus epidermidis (MIC=0.2 ?g/ml), Enterococcus faecalis (MIC=4 ?g/ml).##Yeast: Candida albicans (MIC=4 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03864	RRWKIVVIRWRR	12	Sub5 (Bac2A variant through five amino acids substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=2 ?g/ml), Escherichia coli (MIC=4 ?g/ml), Salmonella typhimurium (MIC=8 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=2 ?g/ml), Staphylococcus epidermidis (MIC=0.5 ?g/ml), Enterococcus faecalis (MIC=2 ?g/ml).##Yeast: Candida albicans (MIC=4 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03865	RWWKIWVIRWWR	12	Sub6 (Bac2A variant through six amino acids substitution)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Optimized 12-mer peptides shows broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=31 ?g/ml), Escherichia coli (MIC=4 ?g/ml), Salmonella typhimurium (MIC=16 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=8 ?g/ml), Staphylococcus epidermidis (MIC=1 ?g/ml), Enterococcus faecalis (MIC=8 ?g/ml).##Yeast: Candida albicans (MIC=31 ?g/ml).."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03866	KIWVIRWR	8	Bac8a (Bac2A variant)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: 8-mer substituted peptide that showes broad spectrum activity against bacteria and the yeast C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=16 ?g/ml), Escherichia coli (MIC=8 ?g/ml), Salmonella typhimurium (MIC=31 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=16 ?g/ml), Staphylococcus epidermidis (MIC=4 ?g/ml), Enterococcus faecalis (MIC=16 ?g/ml).##Yeast: Candida albicans (MIC=16 ?g/ml)"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03867	RIWVIRWR	8	Bac8b (Bac2A variant)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: 8-mer substituted peptide that showes broad spectrum activity against bacteria and the yeast C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=16 ?g/ml), Escherichia coli (MIC=4 ?g/ml), Salmonella typhimurium (MIC=16 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=4 ?g/ml), Staphylococcus epidermidis (MIC=4 ?g/ml), Enterococcus faecalis (MIC=8 ?g/ml).##Yeast: Candida albicans (MIC=16 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03868	RIWVIWRR	8	Bac8c (Bac2A variant)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: 8-mer substituted peptide that showes broad spectrum activity against bacteria and the yeast C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=8 ?g/ml), Escherichia coli (MIC=2 ?g/ml), Salmonella typhimurium (MIC=8 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=2 ?g/ml), Staphylococcus epidermidis (MIC=2 ?g/ml), Enterococcus faecalis (MIC=2 ?g/ml).##Yeast: Candida albicans (MIC=8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03869	RRWVIWRR	8	Bac8d (Bac2A variant)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: 8-mer substituted peptide that showes broad spectrum activity against bacteria and the yeast C. albicans.
Chemical modification: C-terminal amidation."	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=250 ?g/ml), Escherichia coli (MIC=16 ?g/ml), Salmonella typhimurium (MIC=31 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=16 ?g/ml), Staphylococcus epidermidis (MIC=8 ?g/ml), Enterococcus faecalis (MIC=32 ?g/ml).##Yeast: Candida albicans (MIC=63 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366	Nat Biotechnol. 2005 Aug;23(8):1008-1012.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.
DRAMP03870	RLARIVVIRVAR	12	Bac2A (a linear variant of bovine dodecapeptide)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=50 ?g/ml), Escherichia coli (MIC=17 ?g/ml), Salmonella (MIC=34 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=17 ?g/ml), Staphylococcus epidermidis (MIC=4 ?g/ml), Enterococcus faecalis (MIC=17 ?g/ml).##Yeast: Candida albicans (MIC=9 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16041366##17052614	Nat Biotechnol. 2005 Aug;23(8):1008-1012.Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Volkmer-Engert R, Walter T, Hancock RE. Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	High-throughput generation of small antibacterial peptides with improved activity.Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP03930	KWKLFKKLKVLTTGL	15	Cecropin A (1-7)-melittin (6-13)hybrid peptide	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli D21 (MIC=2 ?M), Pseudomonas aeruginosa OT97 (MIC=8 ?M);##Gram-positive bacteria: Bacillus subtilis Bs11 (MIC=1 ?M), Bacillus megaterium Bm11 (MIC=0.5 ?M), Staphylococcus aureus Cowan 1 (MIC=51 ?M), Streptococcus pyogenes (MIC=0.4 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1733777	FEBS Lett. 1992 Jan 20;296(2):190-194.	"Andreu D, Ubach J, Boman A, W??hlin B, Wade D, Merrifield RB, Boman HG."	Shortened cecropin A-melittin hybrids. Significant size reduction retains potent antibiotic activity.
DRAMP03933	IIYCNRRTGKCQRM	14	"I14M (truncated isoform of thanatin, residue 8-21)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-positive bacteria: Aerococcus viridans (MIC=1.2-2.5 ?M), Micrococcus luteus (MIC=5-10 ?M), Bacillus megaterium (MIC=10-20 ?M);##Gram-negative bacteria: Escherichia coli D22 (MIC=20-40 ?M), Escherichia coli D31 (MIC=20-40 ?M), Klebsiella pneumoniae (MIC=20-40 ?M).##Fungi: Neurospora crassa (MIC=20-40 ?M), Botrytis cinerea (MIC=10-20 ?M), Alternaria brassicicola (MIC=5-10 ?M), Fusarium culmorum (MIC=20-40 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8577744	Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-1225.	"Fehlbaum P, Bulet P, Chernysh S, Briand JP, Roussel JP, Letellier L, Hetru C, Hoffmann JA."	"Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides."
DRAMP03934	YCNRRTGKCQRM	12	"Y12M (truncated isoform of thanatin, residue 10-21)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-positive bacteria: Aerococcus viridans (MIC=20-40 ?M), Micrococcus luteus (MIC=20-40 ?M), Bacillus megaterium (MIC=20-40 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8577744	Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-1225.	"Fehlbaum P, Bulet P, Chernysh S, Briand JP, Roussel JP, Letellier L, Hetru C, Hoffmann JA."	"Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides."
DRAMP03935	VPIIYCNRRTGKCQRM	16	"V16M (truncated isoform of thanatin, residue 6-21)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-positive bacteria: Aerococcus viridans (MIC=1.2-2.5 ?M), Micrococcus luteus (MIC=2.5-5 ?M), Bacillus megaterium (MIC=5-10 ?M), Bacillus subtilis (MIC=20-40 ?M), Pediococcus acidilactici (MIC=20-40 ?M);##Gram-negative bacteria: Escherichia coli D22 (MIC=0.6-1.2 ?M), Escherichia coli D31 (MIC=0.6-1.2 ?M), Klebsiella pneumoniae (MIC=2.5-5 ?M), Enterobacter cloacae (MIC=5-10 ?M), E. carotovora (MIC=20-40 ?M).##Fungi: Neurospora crassa (MIC=10-20 ?M), Botrytis cinerea (MIC=10-20 ?M), Nectria haematococca (MIC=5-10 ?M), Trichoderma viride (MIC=20-40 ?M), Alternaria brassicicola (MIC=5-10 ?M), Fusarium culmorum (MIC=10-20 ?M), A. pisi (MIC=20-40 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8577744	Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-1225.	"Fehlbaum P, Bulet P, Chernysh S, Briand JP, Roussel JP, Letellier L, Hetru C, Hoffmann JA."	"Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides."
DRAMP03936	KPVPIIYCNRRTGKCQRM	18	"K18M (truncated isoform of thanatin, residue 4-21)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-positive bacteria: Aerococcus viridans (MIC=0.6-1.2 ?M), Micrococcus luteus (MIC=1.2-2.5 ?M), Bacillus megaterium (MIC=2.5-5 ?M), Bacillus subtilis (MIC=20-40 ?M), Pediococcus acidilactici (MIC=20-40 ?M);##Gram-negative bacteria: Escherichia coli D22 (MIC=0.3-0.6 ?M), Escherichia coli D31 (MIC=0.3-0.6 ?M), Escherichia coli 1106 (MIC=0.6-1.2 ?M), Salmonella typhimuriumn (MIC=1.2-2.5 ?M), Klebsiella pneumoniae (MIC=1.2-2.5 ?M), Enterobacter cloacae (MIC1.2-2.5 ?M), E. carotovora (MIC=20-40 ?M), Pseudomonas aeruginosa (MIC=20-40 ?M).##Fungi: Neurospora crassa (MIC=2.5-5 ?M), Botrytis cinerea (MIC=1.2-2.5 ?M), Nectria haematococca (MIC=5-10 ?M), Trichoderma viride (MIC=2.5-5 ?M), Alternaria brassicicola (MIC=2.5-5 ?M), Fusarium culmorum (MIC=5-10 ?M), A. pisi (MIC=10-20 ?M), Fusarium oxysporumn (MIC=20-40 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8577744	Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-1225.	"Fehlbaum P, Bulet P, Chernysh S, Briand JP, Roussel JP, Letellier L, Hetru C, Hoffmann JA."	"Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides."
DRAMP03937	GSKKPVPIIYCNRRTGKC	18	"G18C (truncated isoform of thanatin, residue 1-18)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-positive bacteria: Aerococcus viridans (MIC=2.5-5 ?M), Micrococcus luteus (MIC=1.2-2.5 ?M), Bacillus megaterium (MIC=5-10 ?M), Bacillus subtilis (MIC=5-10 ?M), Pediococcus acidilactici (MIC=20-40 ?M).##Fungi: Neurospora crassa (MIC=10-20 ?M), Botrytis cinerea (MIC=5-10 ?M), Nectria haematococca (MIC=5-10 ?M), Trichoderma viride (MIC=20-40 ?M), Alternaria brassicicola (MIC=5-10 ?M), Fusarium culmorum (MIC=10-20 ?M), A. pisi (MIC=20-40 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8577744	Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-1225.	"Fehlbaum P, Bulet P, Chernysh S, Briand JP, Roussel JP, Letellier L, Hetru C, Hoffmann JA."	"Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides."
DRAMP03938	GSKKPVPIIYCNRRTGKCQ	19	"G19Q (truncated isoform of thanatin, residue 1-19)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-positive bacteria: Aerococcus viridans (MIC=2.5-5 ?M), Micrococcus luteus (MIC=5-10 ?M), Bacillus megaterium (MIC=5-10 ?M), Pediococcus acidilactici (MIC=20-40 ?M).##Fungi: Neurospora crassa (MIC=10-20 ?M), Botrytis cinerea (MIC=5-10 ?M), Nectria haematococca (MIC=5-10 ?M), Trichoderma viride (MIC=10-20 ?M), Alternaria brassicicola (MIC=5-10 ?M), Fusarium culmorum (MIC=10-20 ?M), A. pisi (MIC=20-40 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8577744	Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-1225.	"Fehlbaum P, Bulet P, Chernysh S, Briand JP, Roussel JP, Letellier L, Hetru C, Hoffmann JA."	"Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides."
DRAMP03939	GSKKPVPIIYCNRRTGKCQR	20	"G20R (truncated isoform of thanatin, residue 1-20)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-positive bacteria: Aerococcus viridans (MIC=2.5-5 ?M), Micrococcus luteus (MIC=2.5-5 ?M), Bacillus megaterium (MIC=2.5-5 ?M), Bacillus subtilis (MIC20-40 ?M), Pediococcus acidilactici (MIC=20-40 ?M).##Fungi: Neurospora crassa (MIC=5-10 ?M), Botrytis cinerea (MIC=5-10 ?M), Nectria haematococca (MIC=2.5-5 ?M), Trichoderma viride (MIC=10-20 ?M), Alternaria brassicicola (MIC=5-10 ?M), Fusarium culmorum (MIC=10-20 ?M), A. pisi (MIC=10-20 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8577744	Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-1225.	"Fehlbaum P, Bulet P, Chernysh S, Briand JP, Roussel JP, Letellier L, Hetru C, Hoffmann JA."	"Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides."
DRAMP03954	MTKGDTKVMKCVLEVISDSLSKPSPMPVSPECLETLQGDERILSVLRHQNL	51	Rat CGA7?€¡°57 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Neurospora crassa (MIC=10 ?g/ml), Alternaria brassicicola (MIC=20 ?g/ml), Nectria haematococca (MIC=10 ?g/ml), Fusarium culmorum (MIC=20 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10753865	J Biol Chem. 2000 Apr 14;275(15):10745-10753.	"Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, Aunis D, Metz-Boutigue MH."	"Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A."
DRAMP03955	STALPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILSILRHQNLLKELQDLALQGAKERAHQQKK	81	Human recombinant Ser-Thr-Ala-CGA1-78 peptide (hrVS-1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Micrococcus luteus (MIC=30 ?M), Bacillus megaterium (MIC=30 ?M).##Fungi: Neurospora crassa (MIC=10 ?M), Alternaria brassicicola (MIC=1 ?M), Nectria haematococca (MIC=3 ?M), Fusarium culmorum (MIC=5 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10753865	J Biol Chem. 2000 Apr 14;275(15):10745-10753.	"Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, Aunis D, Metz-Boutigue MH."	"Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A."
DRAMP03957	RILSILRHQNLLKE	14	CGA47-60 (hrVS-1-derived peptide)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Neurospora crassa (MIC=7 ?M), Aspergillus fumigatus (MIC=50 ?M), Alternaria brassicicola (MIC=10 ?M), Nectria haematococca (MIC=7 ?M), Fusarium culmorum (MIC=20 ?M), F. oxyporum (MIC=50 ?M), Trichophyton mentagrophytes (MIC=50 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10753865	J Biol Chem. 2000 Apr 14;275(15):10745-10753.	"Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, Aunis D, Metz-Boutigue MH."	"Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A."
DRAMP03958	TLRGDERILSILRHQNLLKE	20	CGA41-60 (hrVS-1-derived peptide)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Neurospora crassa (MIC=100 ?M), Nectria haematococca (MIC=30 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10753865	J Biol Chem. 2000 Apr 14;275(15):10745-10753.	"Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, Aunis D, Metz-Boutigue MH."	"Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A."
DRAMP03959	TLRGDERILSILRHQNLLKELQDLALQGAK	30	CGA41-70 (hrVS-1-derived peptide)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Neurospora crassa (MIC=7 ?M), Alternaria brassicicola (MIC=7 ?M), Nectria haematococca (MIC=7 ?M), Fusarium culmorum (MIC=10 ?M), F. oxyporum (MIC=30 ?M), Trichophyton mentagrophytes (MIC=30 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10753865	J Biol Chem. 2000 Apr 14;275(15):10745-10753.	"Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, Aunis D, Metz-Boutigue MH."	"Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A."
DRAMP03960	RILSILRHQNLLKELQDLALQGAK	24	CGA47-70 (hrVS-1-derived peptide)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Neurospora crassa (MIC=5 ?M), Aspergillus fumigatus (MIC=30 ?M), Alternaria brassicicola (MIC=10 ?M), Nectria haematococca (MIC=7 ?M), Fusarium culmorum (MIC=10 ?M), F. oxyporum (MIC=30 ?M), Trichophyton mentagrophytes (MIC=30 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10753865	J Biol Chem. 2000 Apr 14;275(15):10745-10753.	"Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, Aunis D, Metz-Boutigue MH."	"Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A."
DRAMP04019	RAVAVIIRLRRV	12	Bac014 (Scrambled Variants of Bac2A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=23 ?g/ml), Escherichia coli (MIC=11 ?g/ml), Salmonella (MIC=11 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=23 ?g/ml), Staphylococcus epidermidis (MIC=6 ?g/ml).##Yeast: Candida albicans (MIC=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04020	RRAAVVLIVIRR	12	Bac020 (Scrambled Variants of Bac2A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=11 ?g/ml), Escherichia coli (MIC=6 ?g/ml), Salmonella (MIC=23 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=11 ?g/ml), Staphylococcus epidermidis (MIC=1.5 ?g/ml).##Yeast: Candida albicans (MIC=11 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04021	VRLRIRVAVIRA	12	Bac034 (Scrambled Variants of Bac2A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=25 ?g/ml), Escherichia coli (MIC=3 ?g/ml), Salmonella (MIC=12 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=25 ?g/ml), Staphylococcus epidermidis (MIC=3 ?g/ml).##Yeast: Candida albicans (MIC=12 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04022	VRFRIRVAVIRA	12	"F3 (single amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=6 ?g/ml), Escherichia coli (MIC=1.6 ?g/ml), Salmonella (MIC=6 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=12 ?g/ml), Staphylococcus epidermidis (MIC=1.6 ?g/ml).##Yeast: Candida albicans (MIC=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04023	VRWRIRVAVIRA	12	"W3 (single amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=6 ?g/ml), Escherichia coli (MIC=1.6 ?g/ml), Salmonella (MIC=6 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=12 ?g/ml), Staphylococcus epidermidis (MIC=1.6 ?g/ml).##Yeast: Candida albicans (MIC=12 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04024	VRLWIRVAVIRA	12	"W4 (single amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC>50 ?g/ml), Escherichia coli (MIC=6 ?g/ml), Salmonella (MIC>50 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=50 ?g/ml), Staphylococcus epidermidis (MIC=3 ?g/ml).##Yeast: Candida albicans (MIC=50 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04025	VRLRIRVAVRRA	12	"R10 (single amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=12 ?g/ml), Escherichia coli (MIC=6 ?g/ml), Salmonella (MIC=6 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=12 ?g/ml), Staphylococcus epidermidis (MIC=1.6 ?g/ml).##Yeast: Candida albicans (MIC=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04026	VRLRIRVAVIRK	12	"K12 (single amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=6 ?g/ml), Escherichia coli (MIC=3 ?g/ml), Salmonella (MIC=6 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=6 ?g/ml), Staphylococcus epidermidis (MIC=1.6 ?g/ml).##Yeast: Candida albicans (MIC=3 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04027	VQLRIRVRVIRK	12	"opt1 (multiple amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=6 ?g/ml), Escherichia coli (MIC=3 ?g/ml), Salmonella (MIC=6 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=12 ?g/ml), Staphylococcus epidermidis (MIC=1.6 ?g/ml).##Yeast: Candida albicans (MIC=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04028	VRLRIRVRVIRK	12	"opt2 (multiple amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=3 ?g/ml), Escherichia coli (MIC=1.6 ?g/ml), Salmonella (MIC=6 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=6 ?g/ml), Staphylococcus epidermidis (MIC=0.8 ?g/ml).##Yeast: Candida albicans (MIC=3 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04029	KQFRIRVRVIRK	12	"opt3 (multiple amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=6 ?g/ml), Escherichia coli (MIC=3 ?g/ml), Salmonella (MIC=6 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=12 ?g/ml), Staphylococcus epidermidis (MIC=1.6 ?g/ml).##Yeast: Candida albicans (MIC=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04030	KRFRIRVRVIRK	12	"opt4 (multiple amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=6 ?g/ml), Escherichia coli (MIC=1.6 ?g/ml), Salmonella (MIC=3 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=6 ?g/ml), Staphylococcus epidermidis (MIC=0.8 ?g/ml).##Yeast: Candida albicans (MIC=12 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04031	KRWRIRVRVIRK	12	"opt5 (multiple amino acid substitution of Bac034, which is a scrambled Variant of Bac2A)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa (MIC=3 ?g/ml), Escherichia coli (MIC=1.6 ?g/ml), Salmonella (MIC=3 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=3 ?g/ml), Staphylococcus epidermidis (MIC=0.8 ?g/ml).##Yeast: Candida albicans (MIC=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17052614	Chem Biol. 2006 Oct;13(10):1101-1107.	"Hilpert K, Elliott MR, Volkmer-Engert R, Henklein P, Donini O, Zhou Q, Winkler DF, Hancock RE."	Sequence requirements and an optimization strategy for short antimicrobial peptides.
DRAMP04075	AKKVFKRLEKLFSKIQNDK	19	Antimicrobial peptide HP (2-20)	P56029	Not found	rplA	Synthetic construct (amino acid substitution)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix (1 helices; 11 residues)	Not found	1P0G resolved by NMR.	Function: Peptides originating from the N-terminal end of L1 have antibacterial activity against bacteria such as E. coli and Bacillus megaterium and modest antifungal activities. Has no effect on H. pylori itself. Peptides are not hemolytic against mammalian cells. These peptides may be released in the stomach during altruistic lysis to kill other fast growing bacteria.	"[Ref.16255716]Gram-positive bacteria: Bacillus subtilis (MIC=3.13 ?g/ml), Staphylococcus epidermidis (MIC=6.25 ?g/ml), Staphylococcus aureus (MIC=12.5 ?g/ml), Listeria monocytogenes (MIC=6.25 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=3.13 ?g/ml), Salmonella typhimurium (MIC=1.56 ?g/ml), Proteus vulgaris (MIC=6.25 ?g/ml), Pseudomonas aeruginosa (MIC=6.25 ?g/ml), Escherichia coli O157 (MIC=12.5 ?g/ml);##Fungi: Trichosporon beigelii (MIC=3.13 ?g/ml), Candida albicans (MIC>25 ?g/ml), Saccharomyces cerevisiae (MIC>25 ?g/ml), Aspergillus flavus (MIC=50 ?g/ml), Aspergillus fumigatus (MIC>50 ?g/ml), Botrytis cinerea (MIC=12.5 ?g/ml), Fusarium moniliforme (MIC=25 ?g/ml)."	[Swiss_Prot Entry P56029]Non-hemolytic against mammalian cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Phospholipids	16255716##PubMed ID is not available##PubMed ID is not available	Biochem J. 2006 Feb 15;394(Pt 1):105-114.##Submitted (SEP-2004) to the PDB data bank.##To be published	"Lee KH, Lee DG, Park YK, Harm KS, Kim YM.##Lee KH, Lee DG, Park YK, Harm KS, Kim YM.##Lee KH, Lee DG, Park YK, Harm KS, Kim YM."	"Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori.##Structure of antimicrobial peptide, HP (2-20) and its analogues derived from Helicobacter pylori, as determined by 1H NMR spectroscopy.##Interactions between antimicrobial peptide, HP(2-20) derived from helicobacter pylori, and membrain studied by nmr spectroscopy."
DRAMP04076	AKKVFKRLEKLFSKIQNWK	19	Anal 1 (antimicrobial peptide HP (2-20)analogue)	P56029	Not found	Not found	Synthetic construct (amino acid substitution)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix (1 helices; 14 residues)	Not found	1P0J resolved by NMR.	Function: Has antibacterial and antifungal activiy. 	"Gram-positive bacteria: Bacillus subtilis (MIC=1.56 ?g/ml), Staphylococcus epidermidis (MIC=3.13 ?g/ml), Staphylococcus aureus (MIC=3.13 ?g/ml), Listeria monocytogenes (MIC=0.78 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=0.78 ?g/ml), Salmonella typhimurium (MIC=0.39 ?g/ml), Proteus vulgaris (MIC=3.13 ?g/ml), Pseudomonas aeruginosa (MIC=3.13 ?g/ml), Escherichia coli O157 (MIC=6.25 ?g/ml).##Fungi: Trichosporon beigelii (MIC=1.56 ?g/ml), Candida albicans (MIC=25 ?g/ml), Saccharomyces cerevisiae (MIC=25 ?g/ml), Aspergillus flavus (MIC=50 ?g/ml), Aspergillus fumigatus (MIC>50 ?g/ml), Botrytis cinerea (MIC=6.25 ?g/ml), Fusarium moniliforme (MIC=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16255716##PubMed ID is not available	Biochem J. 2006 Feb 15;394(Pt 1):105-114.##To be published	"Lee KH, Lee DG, Park Y, Kang DI, Shin SY, Hahm KS, Kim Y.##Lee KH, Lee DG, Park YK, Harm KS, Kim YM."	"Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori.##Interactions between antimicrobial peptide, HP(2-20) derived from helicobacter pylori, and membrain studied by nmr spectroscopy."
DRAMP04077	AKKVFKRLEKLFSKIWNDK	19	Anal 2 (antimicrobial peptide HP (2-20)analogue)	P56029	Not found	Not found	Synthetic construct (amino acid substitution)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix (1 helices; 14 residues)	Not found	1P0L resolved by NMR.	Function: Has antibacterial and antifungal activiy. 	"Gram-positive bacteria: Bacillus subtilis (MIC=1.56 ?g/ml), Staphylococcus epidermidis (MIC=3.13 ?g/ml), Staphylococcus aureus (MIC=6.25 ?g/ml), Listeria monocytogenes (MIC=1.56 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=3.13 ?g/ml), Salmonella typhimurium (MIC=0.78 ?g/ml), Proteus vulgaris (MIC=3.13 ?g/ml), Pseudomonas aeruginosa (MIC=6.25 ?g/ml), Escherichia coli O157 (MIC=6.25 ?g/ml).##Fungi: Trichosporon beigelii (MIC=1.56 ?g/ml), Candida albicans (MIC=25 ?g/ml), Saccharomyces cerevisiae (MIC=25 ?g/ml), Aspergillus flavus (MIC=50 ?g/ml), Aspergillus fumigatus (MIC>50 ?g/ml), Botrytis cinerea (MIC=6.25 ?g/ml), Fusarium moniliforme (MIC=25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16255716##PubMed ID is not available	Biochem J. 2006 Feb 15;394(Pt 1):105-114.##To be published	"Lee KH, Lee DG, Park Y, Kang DI, Shin SY, Hahm KS, Kim Y.##Lee KH, Lee DG, Park YK, Harm KS, Kim YM."	"Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori.##Interactions between antimicrobial peptide, HP(2-20) derived from helicobacter pylori, and membrain studied by nmr spectroscopy."
DRAMP04078	AKKVFKRLEKLFSKIWNWK	19	Anal 3 (antimicrobial peptide HP (2-20)analogue)	P56029	Not found	Not found	Synthetic construct (amino acid substitution)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix (1 helices; 14 residues)	Not found	1P0O resolved by NMR.	Function: Has antibacterial and antifungal activiy. 	"Gram-positive bacteria: Bacillus subtilis (MIC=1.56 ?g/ml), Staphylococcus epidermidis (MIC=3.13 ?g/ml), Staphylococcus aureus (MIC=1.56 ?g/ml), Listeria monocytogenes (MIC=0.39 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=1.56 ?g/ml), Salmonella typhimurium (MIC=0.39 ?g/ml), Proteus vulgaris (MIC=3.13 ?g/ml), Pseudomonas aeruginosa (MIC=3.13 ?g/ml), Escherichia coli O157 (MIC=3.13 ?g/ml).##Fungi: Trichosporon beigelii (MIC=1.56 ?g/ml), Candida albicans (MIC=12.5 ?g/ml), Saccharomyces cerevisiae (MIC=25 ?g/ml), Aspergillus flavus (MIC=25 ?g/ml), Aspergillus fumigatus (MIC=25 ?g/ml), Botrytis cinerea (MIC=3.13 ?g/ml), Fusarium moniliforme (MIC=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16255716##PubMed ID is not available	Biochem J. 2006 Feb 15;394(Pt 1):105-114.##To be published	"Lee KH, Lee DG, Park Y, Kang DI, Shin SY, Hahm KS, Kim Y.##Lee KH, Lee DG, Park YK, Harm KS, Kim YM."	"Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori.##Interactions between antimicrobial peptide, HP(2-20) derived from helicobacter pylori, and membrain studied by nmr spectroscopy."
DRAMP04079	AKKVFKRLEKSFSKIQNDK	19	Anal 4 (antimicrobial peptide HP (2-20)analogue)	P56029	Not found	Not found	Synthetic construct (amino acid substitution)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix (1 helices; 13 residues)	Not found	1P5K resolved by NMR.	Function: Has antibacterial and antifungal activiy. 	"Gram-positive bacteria: Bacillus subtilis (MIC=6.25 ?g/ml), Staphylococcus epidermidis (MIC>12.5 ?g/ml), Staphylococcus aureus (MIC>12.5 ?g/ml), Listeria monocytogenes (MIC>12.5 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=12.5 ?g/ml), Salmonella typhimurium (MIC=12.5 ?g/ml), Proteus vulgaris (MIC>12.5 ?g/ml), Pseudomonas aeruginosa (MIC=12.5 ?g/ml), Escherichia coli O157 (MIC>12.5 ?g/ml).##Fungi: Trichosporon beigelii (MIC=12.5 ?g/ml), Candida albicans (MIC>25 ?g/ml), Saccharomyces cerevisiae (MIC>25 ?g/ml), Aspergillus flavus (MIC>50 ?g/ml), Aspergillus fumigatus (MIC>50 ?g/ml), Botrytis cinerea (MIC>50 ?g/ml), Fusarium moniliforme (MIC>50 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16255716##PubMed ID is not available	Biochem J. 2006 Feb 15;394(Pt 1):105-114.##To be published	"Lee KH, Lee DG, Park Y, Kang DI, Shin SY, Hahm KS, Kim Y.##Lee KH, Lee DG, Park YK, Harm KS, Kim YM."	"Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori.##Interactions between antimicrobial peptide, HP(2-20) derived from helicobacter pylori, and membrain studied by nmr spectroscopy."
DRAMP04080	AKKVSKRLEKLFSKIQNDK	19	Anal 5 (antimicrobial peptide HP (2-20)analogue)	P56029	Not found	Not found	Synthetic construct (amino acid substitution)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix (1 helices; 12 residues)	Not found	1P5L resolved by NMR.	Function: Has antibacterial and antifungal activiy. 	"Gram-positive bacteria: Bacillus subtilis (MIC=3.13 ?g/ml), Staphylococcus epidermidis (MIC=12.5 ?g/ml), Staphylococcus aureus (MIC>12.5 ?g/ml), Listeria monocytogenes (MIC>12.5 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=6.25 ?g/ml), Salmonella typhimurium (MIC=12.5 ?g/ml), Proteus vulgaris (MIC>12.5 ?g/ml), Pseudomonas aeruginosa (MIC=12.5 ?g/ml), Escherichia coli O157 (MIC=6.25 ?g/ml).##Fungi: Trichosporon beigelii (MIC=12.5 ?g/ml), Candida albicans (MIC>25 ?g/ml), Saccharomyces cerevisiae (MIC>25 ?g/ml), Aspergillus flavus (MIC>50 ?g/ml), Aspergillus fumigatus (MIC>50 ?g/ml), Botrytis cinerea (MIC>50 ?g/ml), Fusarium moniliforme (MIC>50 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16255716##PubMed ID is not available	Biochem J. 2006 Feb 15;394(Pt 1):105-114.##To be published	"Lee KH, Lee DG, Park Y, Kang DI, Shin SY, Hahm KS, Kim Y.##Lee KH, Lee DG, Park YK, Harm KS, Kim YM."	"Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori.##Interactions between antimicrobial peptide, HP(2-20) derived from helicobacter pylori, and membrain studied by nmr spectroscopy."
DRAMP04081	AKKVFKRLEKLFSKIFNFK	19	Anal 6 (antimicrobial peptide HP (2-20)analogue)	P56029	Not found	Not found	Synthetic construct (amino acid substitution)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix 	Not found	None	Function: Has antibacterial and antifungal activiy. 	"Gram-positive bacteria: Bacillus subtilis (MIC=1.56 ?g/ml), Staphylococcus epidermidis (MIC=6.25 ?g/ml), Staphylococcus aureus (MIC=3.13 ?g/ml), Listeria monocytogenes (MIC=0.78 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=3.13 ?g/ml), Salmonella typhimurium (MIC=0.39 ?g/ml), Proteus vulgaris (MIC=3.125 ?g/ml), Pseudomonas aeruginosa (MIC=6.25 ?g/ml), Escherichia coli O157 (MIC=6.25 ?g/ml).##Fungi: Trichosporon beigelii (MIC=3.13 ?g/ml), Candida albicans (MIC>25 ?g/ml), Saccharomyces cerevisiae (MIC=25 ?g/ml), Aspergillus flavus (MIC=50 ?g/ml), Aspergillus fumigatus (MIC=50-25 ?g/ml), Botrytis cinerea (MIC=12.5 ?g/ml), Fusarium moniliforme (MIC=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16255716##PubMed ID is not available	Biochem J. 2006 Feb 15;394(Pt 1):105-114.##To be published	"Lee KH, Lee DG, Park Y, Kang DI, Shin SY, Hahm KS, Kim Y.##Lee KH, Lee DG, Park YK, Harm KS, Kim YM."	"Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori.##Interactions between antimicrobial peptide, HP(2-20) derived from helicobacter pylori, and membrain studied by nmr spectroscopy."
DRAMP04082	AKKVFKRLEKLFSKIYNYK	19	Anal 7 (antimicrobial peptide HP (2-20)analogue)	P56029	Not found	Not found	Synthetic construct (amino acid substitution)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix 	Not found	None	Function: Has antibacterial and antifungal activiy. 	"Gram-positive bacteria: Bacillus subtilis (MIC=1.56 ?g/ml), Staphylococcus epidermidis (MIC=3.13 ?g/ml), Staphylococcus aureus (MIC=3.13 ?g/ml), Listeria monocytogenes (MIC=0.78 ?g/ml);##Gram-negative bacteria: Escherichia coli (MIC=3.13 ?g/ml), Salmonella typhimurium (MIC=0.39 ?g/ml), Proteus vulgaris (MIC=6.25-3.13 ?g/ml), Pseudomonas aeruginosa (MIC=3.13 ?g/ml), Escherichia coli O157 (MIC=3.13 ?g/ml).##Fungi: Trichosporon beigelii (MIC=1.56 ?g/ml), Candida albicans (MIC=12.5 ?g/ml), Saccharomyces cerevisiae (MIC=25 ?g/ml), Aspergillus flavus (MIC=50 ?g/ml), Aspergillus fumigatus (MIC=50-25 ?g/ml), Botrytis cinerea (MIC=6.25 ?g/ml), Fusarium moniliforme (MIC=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16255716##PubMed ID is not available	Biochem J. 2006 Feb 15;394(Pt 1):105-114.##To be published	"Lee KH, Lee DG, Park Y, Kang DI, Shin SY, Hahm KS, Kim Y.##Lee KH, Lee DG, Park YK, Harm KS, Kim YM."	"Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori.##Interactions between antimicrobial peptide, HP(2-20) derived from helicobacter pylori, and membrain studied by nmr spectroscopy."
DRAMP04096	EQEENVVKIQAFWKGYKQRKEYM	23	2IQ2	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Displays antimicrobial activity against bacteria and yeast C. albicans.	Gram-negative bacterium: Escherichia coli (MIC=2.1 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=32 ?M).##Yeast: Candida albicans (MIC=28 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23238369	Biochimie. 2013 Apr;95(4):875-880.	"McLean DT, Lundy FT, Timson DJ."	IQ-motif peptides as novel anti-microbial agents.
DRAMP04097	DNTDSVVKIQSWFRMATARKSYL	23	2IQ3	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Displays antimicrobial activity against bacteria and yeast C. albicans.	Gram-negative bacterium: Escherichia coli (MIC=1.2 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=26 ?M).##Yeast: Candida albicans (MIC=25 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23238369	Biochimie. 2013 Apr;95(4):875-880.	"McLean DT, Lundy FT, Timson DJ."	IQ-motif peptides as novel anti-microbial agents.
DRAMP04098	ANVGFVIQLQARLRGFLVRQKFA	23	3IQ1	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Displays antimicrobial activity against bacteria and yeast C. albicans.	Gram-negative bacterium: Escherichia coli (MIC=1.7 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=1.7 ?M).##Yeast: Candida albicans (MIC>94 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23238369	Biochimie. 2013 Apr;95(4):875-880.	"McLean DT, Lundy FT, Timson DJ."	IQ-motif peptides as novel anti-microbial agents.
DRAMP04099	TWLPAVIKIQAHWRGYRQRKIYL	23	3IQ2	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Displays antimicrobial activity against bacteria and yeast C. albicans.	Gram-negative bacterium: Escherichia coli (MIC=1.9 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=1.6 ?M).##Yeast: Candida albicans (MIC=25 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23238369	Biochimie. 2013 Apr;95(4):875-880.	"McLean DT, Lundy FT, Timson DJ."	IQ-motif peptides as novel anti-microbial agents.
DRAMP04100	ANLDAIIKIQAWARMWAARRQYL	23	3IQ3	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Displays antimicrobial activity against bacteria and yeast C. albicans.	Gram-negative bacterium: Escherichia coli (MIC=2 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=11 ?M).##Yeast: Candida albicans (MIC>89 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23238369	Biochimie. 2013 Apr;95(4):875-880.	"McLean DT, Lundy FT, Timson DJ."	IQ-motif peptides as novel anti-microbial agents.
DRAMP04101	KNVNSIVKIQAFFRARKAQDDYR	23	3IQ4	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Displays antimicrobial activity against bacteria and yeast C. albicans.	Gram-negative bacterium: Escherichia coli (MIC=3.5 ?M);##Gram-positive bacterium: Staphylococcus aureus (MIC=4.6 ?M).##Yeast: Candida albicans (MIC=30 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23238369	Biochimie. 2013 Apr;95(4):875-880.	"McLean DT, Lundy FT, Timson DJ."	IQ-motif peptides as novel anti-microbial agents.
DRAMP04147	WFRKQLKW	8	L10	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-negative bacteria: Escherichia coli ATCC 25923 (MIC=0.8 ?M), Klebsiella pneumoniae (MIC=3.35 ?M), Acinetobacter sp. (MIC=3.35 ?M), Psudomonas aruginosa (MIC=6.71 ?M).##Fungi: Candida albicans ATCC SC5314 (MIC=10.49 ?M), C. tropicalis ATCC 13803 (MIC=20.98 ?M), C. parapsilosis ATCC 22019 (MIC=5.24 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipopolysaccharide (LPS)-binding	23026014	Biochim Biophys Acta. 2013 Feb;1828(2):677-686.	"Mishra B, Leishangthem GD, Gill K, Singh AK, Das S, Singh K, Xess I, Dinda A, Kapil A, Patro IK, Dey S."	"A novel antimicrobial peptide derived from modified N-terminal domain of bovine lactoferrin: Design, synthesis, activity against multidrug-resistant bacteria and Candida."
DRAMP04159	RIKRFWPVVIRTVVAGYNLYRAIKK	25	LR2 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04160	RIKRFWPVVIRTVVAGYNLYRAIK	24	LR3 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=7.032 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=2.344 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=0.586 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04161	RIKRFWPVVIRTVVAGYNLYRAI	23	LR4 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=37.5 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=37.5 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=9.375 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04162	RIKRFWPVVIRTVVAGYNLYRA	22	LR5 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus ATCC25923 (MIC=75 ?g/ml);##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=4.688 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=4.688 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04163	RIKRFWPVVIRTVVAGYNLYR	21	LR6 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04164	RIKRFWPVVIRTVVAGYNLY	20	LR7 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04165	RIKRFWPVVIRTVVAGYNL	19	LR8 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04166	RIKRFWPVVIRTVVAGYN	18	LR9 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04167	RIKRFWPVVIRTVVAGY	17	LR10 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04168	RIKRFWPVVIRTVVAG	16	LR11 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04169	RIKRFWPVVIRTVV	14	LR13 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04170	RIKRFWPVVIRT	12	LR15 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04171	RIKRFWPVVIR	11	LR16 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct (De novo design)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis (MIC=4.688 ?g/ml), Staphylococcus aureus ATCC25923 (MIC=9.375 ?g/ml).##Gram-negative bacterium: Escherichia coli ATCC25922 (MIC=3.516 ?g/ml).##Yeast: Candida albicans ATCC2002 (MIC=2.344 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04528	TCRYWCKTPENQTYCCEDEREIPSKVGLKPGKCPPVRPVCPPTRGFFEPPKTCSNDGSCYGADKCCFDRCLGEHVCKPIQTRG	83	CrusEs (cDNA encoding crustin-like peptide)	No entry found	Not found	Not found	"Chinese mitten crab, Eriocheir sinensis"	"Antibacterial, Antifungal, Antiviral, In, Anti-Gram+, Antimicrobial"	Not found	Not found	Not found	None	Function: CrusEs is a potent antibacterial protein against Gram-positive bacteria infection.	"Gram-positive bacteria: M. luteus (MIC=0.23 ?M), B. subtilis (MIC=0.11 ?M), B. thuringiensis (MIC=0.11 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20144896	Dev Comp Immunol. 2010 Jul;34(7):734-740.	"Mu C, Zheng P, Zhao J, Wang L, Zhang H, Qiu L, Gai Y, Song L."	"Molecular characterization and expression of a crustin-like gene from Chinese mitten crab, Eriocheir sinensis."
DRAMP04665	KPFKKLEKVGRNIRDGIIKAGPAVAVIGQATSIARPTGK	39	Px-cec1	No entry found	Not found	Not found	Plutella xylostella (Diamondback moth)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix (CD)	A circular dichroism (CD) analysis revealed that the recombinant Px-cec1 mainly contained ¦Á-helixes.	None	"Function: Recombinant Px-cec1 exhibites a broad spectrum of anti-microbial properties against fungi, Gram-positive and Gram-negative bacteria, but it does not exhibit hemolytic activity against human erythrocytes."	"[Ref.22921836]Gram-positive bacterium: S. aureus (MIC=2 ?M);##Gram-negative bacteria: E. coli (MIC=0.1 ?M), Pseudomonas fluorescent (MIC=1.1 ?M), Salmonella choleraesuis (MIC=2.1 ?M);##Fungi: Aureobasidium pullulans (MIC=4.0 ?M), Aspergillus flavus (MIC=14.5 ?M), Aspergillus fumigatus (MIC=16.0 ?M), Aspergillus niger (MIC=14.6 ?M), Fusarium oxysporum (MIC=8.0 ?M)."	[Ref.22921836]Non-hemolytic activity against human erythrocytes.	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22921836	Protein Expr Purif. 2012 Oct;85(2):230-238. 	"Jin F, Sun Q, Xu X, Li L, Gao G, Xu Y, Yu X, Ren S."	"cDNA cloning and characterization of the antibacterial peptide cecropin 1 from the diamondback moth, Plutella xylostella L."
DRAMP04671	TDHQMAQSACIGVSQDNAYASAIPRDCHGG	30	Myticusin-1	No entry found	Not found	Not found	Mytilus coruscus	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Myticusin-1 exhibites stronger anti-microbial properties against Gram-positive bacteria more than Gram-negative bacteria and fungus.	"Gram-negative bacteria: Escherichia coli (MIC=6.7-12.5 ?M), Vibrio Parahaemolyticus (MIC>25.0 ?M), Pseudomonas aeruginosa (MIC>25.0 ?M), Vibrio.harveyi (MIC=12.5-25.0 ?M).##Gram-positive bacteria: Bacillus subtilis (MIC=1.2-2.5 ?M), Staphylococcus aureus (MIC=2.5-5.0 ?M), Sarcina luteus (MIC=1.2-2.5 ?M), Bacillus megaterium (MIC=2.5-5.0 ?M).##Fungi: Candida albicans (MIC=6.7-12.5 ?M), Monilia albican (MIC=12.5-25.0 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23247103	Fish Shellfish Immunol. 2013 Feb;34(2):610-616.	"Liao Z, Wang XC, Liu HH, Fan MH, Sun JJ, Shen W."	Molecular characterization of a novel antimicrobial peptide from Mytilus coruscus.
DRAMP04676	MFTLKKPLLLLFFLGTISLSLCQEERDADEEEGEMIEEEVKRSLLGTVKDLLIGAGKSAAQSVLKGLSCKLSKDC	75	Brevinin-2HS2A	E7EKE0	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana hainanensis (Odor frog) (Rana hainanensis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antimicrobial activity against some Gram-positive bacteria and fungi but has no activity against a range of Gram- negative bacteria except P.faecalis. Has extremely low hemolytic activity against human erythrocytes.
Tissue specificity: Expressed by the skin glands."	"[Ref.22450466]Gram-positive bacteria: S.aureus ATCC 25923 (MIC=19 ?M), B.licheniformis X39 (MIC=37.5 ?M) and R.rhodochrous X15 (MIC=9.5 ?M);##Gram-negative bacterium: P. faecalis X29 (MIC=9.5 ?M);##Fungi: C. albicans ATCC 2002 (MIC=19 ?M), slime mold 090223 (MIC=37.5 ?M)."	[Ref.22450466]LC50=300 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22450466	Peptides. 2012 Jun;35(2):285-290.	"Wang H, Yu Z, Hu Y, Li F, Liu L, Zheng H, Meng H, Yang S, Yang X, Liu J."	"Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis."
DRAMP04677	MFTMKKPLLLIVLLGIISLSLCEQERAADEEEGEMIEEEVKRSLLGTVKDLLIGAGKSAAQSVLKGLSCKLSKDC	75	Brevinin-2HS2B	E7EKE1	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana hainanensis (Odor frog) (Rana hainanensis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antimicrobial activity against some Gram-positive bacteria and fungi but has no activity against a range of Gram- negative bacteria except P. faecalis. Has low hemolytic activity against human erythrocytes.
Tissue specificity: Expressed by the skin glands."	"[Ref.22450466]Gram-positive bacteria: S.aureus ATCC 25923 (MIC=19 ?M), B. licheniformis X39 (MIC=37.5 ?M) and R. rhodochrous X15 (MIC=9.5 ?M);##Gram-negative bacterium: P. faecalis X29 (MIC=9.5 ?M);##Fungi: C. albicans ATCC 2002 (MIC=19 ?M), slime mold 090223 (MIC=37.5 ?M)."	[Ref.22450466]LC50=300 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22450466	Peptides. 2012 Jun;35(2):285-290.	"Wang H, Yu Z, Hu Y, Li F, Liu L, Zheng H, Meng H, Yang S, Yang X, Liu J."	"Novel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis."
DRAMP04679	FLPFLIPALTSLISSL	16	Senegalin	L0P323	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Kassina senegalensis (Senegal running frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Antimicrobial peptide with activity against the Gram-positive bacterium S. aureus NCTC 10788 and the yeast C. albicans NCPF 1467. Ineffective against the Gram-negative bacterium E. coli NCTC 10418. Induces a dose-dependent contraction of rat urinary bladder smooth muscle (EC50=2.9 nM) and a dose-dependent relaxation of rat tail artery smooth muscle (EC50=37.7 nM).	Gram-positive bacterium: S. aureus NCTC 10788 (MIC=50 ?M). Yeast: C. albicans NCPF 1467 (MIC=150 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23430307	Amino Acids. 2013 May;44(5):1347-1355. 	"Wang H, Li R, Xi X, Meng T, Zhou M, Wang L, Zhang Y, Chen T, Shaw C."	"Senegalin: a novel antimicrobial/myotropic hexadecapeptide from the skin secretion of the African running frog, Kassina senegalensis."
DRAMP00224	KQQLATEAESAGPIL	15	BTL (Bacteriocin)	No entry found	Not found	Not found	Bacillus subtilis B-TL2 (Gram-positive bacteria)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: The peptide exhibits strong inhibitory activity against mycelial growth of Bipolaris maydis, Alternaria brassicae, Aspergillus niger, Cercospora personata.
Biophysicochemical properties: The purified BTL displays thermostability, almost retaining 100% activity at 100 degrees C for 15 min."	"Fungi: Bipolaris maydis, Alternaria brassicae, Aspergillus niger, Cercospora personata."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18241956	Peptides. 2008 Mar;29(3):350-355.	"Zhang B, Xie C, Yang X."	A novel small antifungal peptide from Bacillus strain B-TL2 isolated from tobacco stems.
DRAMP00235	MINRTDCNENSYLEIHNNEGRDTLCFANAGTMPVAIYGVNWVESGNNVVTLQFQRNLSDPRLETITLQKWGSWNPGHIHEILSIRIY	87	AFP1 (Bacteriocin)	No entry found	Not found	Not found	Streptomyces tendae Tu901 (Gram-positive bacteria)	"Antimicrobial, Antifungal"	Not found	Combine helix and strand structure	"Mature AFP1 comprises 86 residues and contains two antiparallel beta-sheets (five and four beta-strands each), that pack against each other in a parallel beta-sandwich."	1G6E resolved by NMR.	"Function: AFP1 is a recently discovered anti-fungal, chitin-binding protein."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	10601197##11350173	J Bacteriol. 1999 Dec;181(24):7421-7429.##J Mol Biol. 2001 May 11;308(4):765-782.	"Bormann C, Baier D, H?rr I, Raps C, Berger J, Jung G, Schwarz H.##Campos-Olivas R, H?rr I, Bormann C, Jung G, Gronenborn AM."	"Characterization of a novel, antifungal, chitin-binding protein from Streptomyces tendae T?901 that interferes with growth polarity.##Solution structure, backbone dynamics and chitin binding of the anti-fungal protein from Streptomyces tendae TU901."
DRAMP00249	YSLQMGATAIKQVKKLFKKKGG	22	Pln149 (Plantaricin 149; Bacteriocin; Derivatives: Pln149a)	No entry found	Not found	Not found	Lactobacillus plantarum NRIC 149 (Gram-positive bacteria)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Alpha helix	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrance	17266050	J. Fermentation Bioeng. 1994;77(3):277-282.	"Kato T, Matsuda T, Ogawa E, Ogawa H, Kato H, Doi U."	"Plantaricin-149, a bacteriocin produced by Lactobacillus plantarum NRIC 149."
DRAMP00252	VNPSYRLDPESRPQCEAHCGQLGMRLGAIVIMGTATGCVCEPKEAATPESR	51	AdDLP (A. dehalogenans defensin-like peptide; Bacteriocin)	No entry found	Not found	Not found	Anaeromyxobacter dehalogenans (Gram-negative bacteria)	"Antibacterial, Antifungal, Antiparasitic, Antimicrobial"	Not found	Not found	"Circular dichroism (CD) analysis indicates that recombinant AdDLP adopts a typical structural feature of eukaryotic defensins, which is also consistent with an ab initio structure model predicted using I-TASSER algorithm."	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19615342	Biochem Biophys Res Commun. 2009 Sep 18;387(2):393-398.	"Gao B, Rodriguez MD, Lanz-Mendoza H, Zhu S."	"AdDLP, a bacterial defensin-like peptide, exhibits anti-Plasmodium activity."
DRAMP00264	EQCREEEDDR	10	Coconut antifungal peptide (Plants)	No entry found	Not found	Not found	Cocos nucifera	"Antimicrobial, Antifungal, Antiviral"	Not found	Not found	Not found	None	Function: Also has HIV-1 reverse transcriptase activity (IC50=52.5 ?M)	"Fungi: Fusarium oxysporum, Mycosphaerella arachidicola (IC50=1.2 ?M), Physalospora piricola."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16308082	Peptides. 2005 Dec;26(12):2392-2396.	"Wang HX, Ng TB."	An antifungal peptide from the coconut.
DRAMP00265	EALYNSEDLYEETSDSDD	18	Putative antimicrobial protein 1 (Ls-AMP1; Plant defensin)	P86895	Not found	Not found	Lippia sidoides (Pepper-rosmarin)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: May possess antifungal activity.
Caution: Antifungal activity was tested using a fraction containing a number of different peptides. It is not clear which peptide actually has antifungal activity."	Fungi: Botrytis cinerea.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21210197	Protein J. 2011 Jan;30(1):32-38.	"Moreira JS, Almeida RG, Tavares LS, Santos MO, Viccini LF, Vasconcelos IM, Oliveira JT, Raposo NR, Dias SC, Franco OL."	Identification of botryticidal proteins with similarity to NBS-LRR proteins in rosemary pepper (Lippia sidoides Cham.) flowers.
DRAMP00266	SPPEAAYGPGNTNSDSGDK	19	Putative antimicrobial protein 2 (Ls-AMP2; Plant defensin)	P86896	Not found	Not found	Lippia sidoides (Pepper-rosmarin)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: May possess antifungal activity.
Caution: Antifungal activity was tested using a fraction containing a number of different peptides. It is not clear which peptide actually has antifungal activity."	Fungi: Botrytis cinerea.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21210197	Protein J. 2011 Jan;30(1):32-38.	"Moreira JS, Almeida RG, Tavares LS, Santos MO, Viccini LF, Vasconcelos IM, Oliveira JT, Raposo NR, Dias SC, Franco OL."	Identification of botryticidal proteins with similarity to NBS-LRR proteins in rosemary pepper (Lippia sidoides Cham.) flowers.
DRAMP00267	ESGINLQGDATLANN	15	Antifungal lectin AMML (AMML; Plant defensin)	P85004	Not found	Not found	Astragalus mongholicus (Huang qi) (Astragalus membranaceus varmongholicus)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Lectin that binds strongly to galactose, lactose, D-raffinose, L-rhamnose and cellobiose, and less strongly to D-glucose, D-xylose and L-arabinose. Does not bind D-galacturonic acid, D-fructose, D-mannose, D-ribose, L-sorbose, maltose and sucrose. Has hemagglutinating activity towards human type O and rabbit erythrocytes. Has strong antifungal activity against B. cinera, and weaker antifungal activity against D. turcia, F. oxysporum and Colletorichum sp. but not against Rhizoctonia solani and Mycosphaerella arachidicola.
Miscellaneous: Hemagglutinating activity stable when incubated at 65 degrees Celsius for 30 minutes. Hemagglutinating activity is reduced by 50% when incubated at 75 degrees Celsius for 30 minutes and is abolished by incubation at 85 degrees Celsius for 30 minutes. Hemagglutinating activity is stable between pH 4.5 and 7.5, but is completely inhibited by incubation below pH 3.0 or above pH 10."	"Fungi: Botrytis cinerea (IC50=1.2 ?M), Drechslera turcia, Fusarium oxysporum and Colletorichum sp."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Galactose and Glucose	16140255	Arch Biochem Biophys. 2005 Oct 1;442(1):72-81.	"Yan Q, Jiang Z, Yang S, Deng W, Han L."	A novel homodimeric lectin from Astragalus mongholicus with antifungal activity.
DRAMP00268	QGIGVGDNDGKRGKR	15	Antifungal protein Pr-2 (Pr-2; Plant defensin)	P86796	Not found	Not found	Cucurbita maxima (Pumpkin) (Winter squash)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has strong antifungal activity. Lacks antifungal activity against P.verrucosum var. verrucosum. Lacks antibacterial activity against the Gram-negative bacterium E.coli and against the Gram-positive bacterium S.aureus. Has very low hemolytic activity against human erythrocytes. Increases fungal cell membrane permeability, probably by disrupting the membrane structure."	"[Ref.19807165]Fungi: Botrytis cinerea (EC50=20 ?M), Candida albicans (EC50=20 ?M), Colletotrichum coccodes (EC50=10 ?M), Fusarium oxysporum (EC50=10 ?M), Fusarium solani (EC50=10 ?M), Trichoderma harzianum (EC50=20 ?M), Trichoderma viride (EC50=20 ?M), Aspergillus fumigatus EC50=40 ?M), Aspergillus parasiticus (EC50=80 ?M), Didymella bryoniae (EC50=40 ?M)."	[Ref:19807165]0% hemolytic activity at 80 ?M and 8% hemolytic activity at 160 ?M against huamn red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19807165	J Agric Food Chem. 2009 Oct 14;57(19):9299-9304.	"Park SC, Kim JY, Lee JK, Hwang I, Cheong H, Nah JW, Hahm KS, Park Y."	Antifungal mechanism of a novel antifungal protein from Pumpkin rinds against various fungal pathogens.
DRAMP00269	LDSLSFSYNNFEEDD	15	Antifungal protein 1 (GAFP-1; Plant defensin)	P86920	Not found	Not found	Arachis hypogaea (Peanut)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Has strong antifungal activity against fungal phytopathogens.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (MAY-2011) to UniProtKB	Indira S.	GAFP-1 from roots of Arachis hypogeae L.
DRAMP00270	ATFTIRNNCPYTIWAAAVPGGGRRLNSGGTWTINVAPGTA	40	Osmotin (CpOsm; Plant defensin)	P86363	Belongs to the thaumatin family	Not found	Calotropis procera (Roostertree) (Asclepias procera)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity.
Miscellaneous: On the 2D-gel the determined pI of isoform 1 is: 8.9, its MW is: 22 kDa. On the 2D-gel the determined pI of isoform 2 is: 9.1, its MW is: 22 kDa."	"Fungi: Fusarium solani (IC50=67.0 ?g/ml), Colletotrichum gloeosporioides (IC50=32.1 ?g/ml), Neurospora isolate (IC50=57.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21334906	Plant Physiol Biochem. 2011 Jul;49(7):738-743. 	"de Freitas CD, Nogueira FC, Vasconcelos IM, Oliveira JT, Domont GB, Ramos MV."	"Osmotin purified from the latex of Calotropis procera: Biochemical characterization, biological activity and role in plant defense."
DRAMP00271	ATFTIRNNXPYTVWAAASPGGGRRLDMARIWGRTNXNFD	39	Osmotin-like protein (Thaumatin-like protein; Plant defensin)	P83491	Belongs to the thaumatin family	Not found	Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: May be an important antifungal protein.
PTM: Contains intrachain disulfide bonds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Plant Physiol. Biochem. 2001;39:1047-1055.	"Subroto T, de Vries H, Schuringa J.J, Soedjanaatmadja U.M.S, Hofsteenge J, Jekel P.A, Beintema J.J."	Enzymic and structural studies on processed proteins from the vacuolar (lutoid-body) fraction of latex of Hevea brasiliensis.
DRAMP00272	AKITFTNNHPRTIWP	15	Thaumatin-like protein (Plants)	P83957	Belongs to the thaumatin family	Not found	Castanopsis chinensis (Chinese chinquapin) (Kweilin chestnut)	"Antimicrobial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Botrytis cinerea, Fusarium oxysporum (IC50=0.5 ?M), Mycosphaerella arachidicola, Psylla piricola.##HIV-1 reverse transcriptase (IC50=1.6 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12565869	Biochem Biophys Res Commun. 2003 Feb 7;301(2):364-370.	"Chu KT, Ng TB."	Isolation of a large thaumatin-like antifungal protein from seeds of the Kweilin chestnut Castanopsis chinensis.
DRAMP00273	ANFEIVNNCPYTVWAAASPGGGRRLDRGQT	30	Thaumatin-like protein (Plants)	P83959	Belongs to the thaumatin family	Not found	Phaseolus vulgaris (Kidney bean) (French bean)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Coprinus comatus, Fusarium oxysporum, Pleurotus ostreatus."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10486265	Biochem Biophys Res Commun. 1999 Sep 16;263(1):130-134.	"Ye XY, Wang HX, Ng TB."	First chromatographic isolation of an antifungal thaumatin-like protein from French bean legumes and demonstration of its antifungal activity.
DRAMP00274	QKIQEIDLQTYLQPQ	15	Amaryllin (Plant defensin)	P86781	Not found	Not found	Amaryllis belladonna (Naked lady lily)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity.	Fungi: Aspergillus flavus and Fusarium oxysporum.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19478451	Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jun 1;65(Pt 6):635-637.	"Kumar S, Singh N, Sinha M, Kaur P, Srinivasan A, Sharma S, Singh TP."	"Isolation, purification, crystallization and preliminary crystallographic studies of amaryllin, a plant pathogenesis-related protein from Amaryllis belladonna."
DRAMP00276	YSYKKIDCGGACAARCRLSSRPRLCNRACGTCCARCNCVPPGTSGNTETCPCYASLTTHGNKRKCP	66	Snakin-2 (StSN2; Cys-rich; Plant defensin)	"Q93X17, A1YN11, Q948Z5"	Not found	SN2	Solanum tuberosum (Potato)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	"Function: Has an antimicrobial activity. Causes a rapid aggregation of both Gram-positive and Gram-negative bacteria, but the antimicrobial activity is not correlated with the capacity to aggregate bacteria.
Tissue specificity: Expressed in tubers, stems, flowers, shoot apex and leaves, but not in roots or stolons.
Induction: Locally up-regulated by abscisic acid, wounding and infection with compatible fungus. Down-regulated by gibberellic acid or infection with virulent bacteria. No responses to ethylene or abiotic stresses.
PTM: Six disulfide bonds may be present."	"Gram-positive bacteria: Clavibacter michiganensis (EC50=4 ?M), Ralstonia solanacearum (EC50=15 ?M).##Fungi: pathogens Rhizobium meliloti (EC50=8 ?M), Botrytis cinerea (EC50=2 ?M), Fusarium solani (EC50=2 ?M), Fusarium culmorum (EC50=2 ?M), Fusarium oxysporum f.sp. conglutinans (EC50=10 ?M), Fusarium oxysporum f.sp.lycopersici (EC50=20 ?M), Plectosphaerella cucumerina (EC50=10 ?M), Colletotrichum graminicola (EC50=10 ?M), Colletotrichum lagenarium (EC50=10 ?M), Bipolaris maydis (EC50=20 ?M), Aspergillus flavus (EC50=20 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11891250	Plant Physiol. 2002 Mar;128(3):951-961.	"Marta Berrocal-Lobo, Ana Segura, Manuel Moreno, Gemma L¨®pez, Francisco Garc¨ªa-Olmedo, Antonio Molina"	"Snakin-2, an antimicrobial peptide from potato whose gene is locally induced by wounding and responds to pathogen infection."
DRAMP00277	DICTNCCAGTKGCNTTSANGAFICEGQSDPKKPKACPLNCDPHIAYA	47	Potamin-1 (PT-1; Plants)	P84813	Belongs to the protease inhibitor I20	Not found	Solanum tuberosum (Potato)	"Antimicrobial, Antifungal, Antibacterial, Anti-Gram+"	Protein level	Not found	Not found	None	"Function: Inhibitor of serine proteases chymotrypsin, papain and trypsin. Has strong antifungal activity against C. albicans and R.solani. Has antibacterial activity against the Gram-positive bacterium C.michiganense, but Non-antibacterial activity against the Gram-positive bacterium S. aureus. Lacks hemolytic activity against human erythrocytes.
PTM: Contains four disulfide bonds (By similarity)."	[Ref.15809084]Fungi: Candida albicans(MIC =100¦ÌM) and Rhizoctonia solani(MIC =100¦ÌM);##Gram-positive bacterium: Clavibacter michiganensis(MIC =50¦ÌM)	[Ref:15809084]Non-hemolytic activity against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15809084	Biochem Biophys Res Commun. 2005 May 13;330(3):921-927.	"Kim JY, Park SC, Kim MH, Lim HT, Park Y, Hahm KS."	Antimicrobial activity studies on a trypsin-chymotrypsin protease inhibitor obtained from potato.
DRAMP00278	LPSDATLVLDQTGKELDARL	20	Antifungal protein J (AFP-J; Plants)	P84794	Belongs to the protease inhibitor I3	Not found	Solanum tuberosum (Potato)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Inhibitor of serine proteases chymotrypsin, pepsin and trypsin. Has strong antifungal activity. Non-hemolytic activity against human erythrocytes."	"[Ref.16076139]Fungi: Candida albicans TIMM 1768(MIC=6.25¦Ìg/mL)), Saccharomyces cerevisiae KCTC 7296(MIC=6.25¦Ìg/mL)), Trichosporon beigelii KCTC 7707(MIC=6.25¦Ìg/mL))"	[Ref:16076139]Non-hemolytic activity against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16076139	J Agric Food Chem. 2005 Aug 10;53(16):6491-6496.	"Park Y, Choi BH, Kwak JS, Kang CW, Lim HT, Cheong HS, Hahm KS."	Kunitz-type serine protease inhibitor from potato (Solanum tuberosum L. cv. Jopung).
DRAMP00280	LIYAKVECLTTGVRTYVGKQSWPELVGTKGKTAAATIDKENTHVTAVLCPPLTTLAACRTFDFRCDRVRVLINRIGGVVTKTPTVG	86	Trypsin inhibitor (FtTI; Plant defensin)	P86971	Not found	Not found	Fagopyrum tataricum (Tartarian buckwheat) (Polygonum tataricum)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Serine protease inhibitor which is active against trypsin. Displays strong antifungal activity against a number of phytopathogenic fungi.
Biophysicochemical properties: pH dependence (Optimum pH is 8.0 at 37 degrees Celsius. Maintains over 90% of its inhibitory activity from pH 3 to 10); Temperature dependence (Active between 10 and 60 degrees Celsius. 84% activity retained when heated for 30 minutes at 80 degrees Celsius. Incubation at temperatures above 80 degrees Celsius rapidly decreases inhibitory activity).
PTM: Contains two disulfide bonds 8-65; 49-58."	"Fungi: M. melonis, A. cucumerina, A. solani, C. glaeosporioides and P. capsici."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21544554	Appl Biochem Biotechnol. 2011 May 5.	"Ruan JJ, Zhou ML, Chen H, Shao JR."	Identification and Characterization of a Trypsin Inhibitor from Fagopyrum tataricum Seeds.
DRAMP00282	GPMRIAEARHCESLSHRFKGPCTRDSNCASVCETERFSGGNCHGFRRRCFCTKPC	55	Defensin-like protein P322 (Probable protease inhibitor P322; Plant defensin)	P20346	Belongs to the DEFL family	Not found	Solanum tuberosum (Potato)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	"Plant Molecular Biology. 1988, 11(3):255-269."	"Stiekema WJ, Heidekamp F, Dirkse WG, van Beckum J, de Haan P, ten Bosch C, Louwerse JD."	Molecular cloning and analysis of four potato tuber mRNAs.
DRAMP00283	RECQSQSHRYKGACVHDTNCASVCQTEGFSGGKCVGFRGRCFCTKAC	47	Defensin Ec-AMP-D1 (Plant defensin)	P86518	Belongs to the DEFL family	Not found	Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity. Inhibits hyphal development in P. infestans (IC50=25.5 ?g/ml), but not release of zoospores. At concentrations above 100 ?g/ml, induces morphological changes such as lysis of hyphae and sporangia in P. infestans.
PTM: Contains four disulfide bonds (By similarity)."	"Fungi: Fusarium graminearum (IC50=15 ?g/ml), Fusarium oxysporum (IC50=102 ?g/ml), F. verticillioides (IC50=8.5 ?g/ml), Diplodia maydis (IC50=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18625284	Biochimie. 2008 Nov-Dec;90(11-12):1667-1673. 	"Odintsova TI, Rogozhin EA, Baranov Y, Musolyamov AKh, Yalpani N, Egorov TA, Grishin EV."	Seed defensins of barnyard grass Echinochloa crusgalli (L.) Beauv.
DRAMP00284	RVCMGKSQHHSFPCISDRLCSNECVKEEGGWTAGYCHLRYCRCQKAC	47	Defensin-like protein 1 (SI alpha-1; Plant defensin)	P21923	Belongs to the DEFL family	Not found	Sorghum bicolor (Sorghum) (Sorghum vulgare)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity (By similarity).
PTM: Contains four disulfide bonds 3-47; 14-36; 20-41; 24-43."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1995329##7705336	FEBS Lett. 1991 Feb 11;279(1):101-104.##Eur J Biochem. 1995 Mar 1;228(2):250-256.	"Bloch C Jr, Richardson M.##Nitti G, Orr¨´ S, Bloch C Jr, Morhy L, Marino G, Pucci P."	A new family of small (5 kDa) protein inhibitors of insect alpha-amylases from seeds or sorghum (Sorghum bicolar (L) Moench) have sequence homologies with wheat gamma-purothionins.##Amino acid sequence and disulphide-bridge pattern of three gamma-thionins from Sorghum bicolor.
DRAMP00285	RVCMGKSAGFKGLCMRDQNCAQVCLQEGWGGGNCDGVMRQCKCIRQCW	48	Defensin-like protein 2 (SI alpha-2; Plant defensin)	P21924	Belongs to the DEFL family	Not found	Sorghum bicolor (Sorghum) (Sorghum vulgare)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity (By similarity).
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1995329	FEBS Lett. 1991 Feb 11;279(1):101-104.	"Bloch C Jr, Richardson M."	A new family of small (5 kDa) protein inhibitors of insect alpha-amylases from seeds or sorghum (Sorghum bicolar (L) Moench) have sequence homologies with wheat gamma-purothionins.
DRAMP00286	RVCRRRSAGFKGLCMSDHNCAQVCLQEGWGGGNCDGVIRQCKCIRQC	47	Defensin-like protein 3 (SI alpha-3; Plant defensin)	P21925	Belongs to the DEFL family	Not found	Sorghum bicolor (Sorghum) (Sorghum vulgare)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity (By similarity).
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1995329##7705336	FEBS Lett. 1991 Feb 11;279(1):101-104.##Eur J Biochem. 1995 Mar 1;228(2):250-256.	"Bloch C Jr, Richardson M.##Nitti G, Orr¨´ S, Bloch C Jr, Morhy L, Marino G, Pucci P."	A new family of small (5 kDa) protein inhibitors of insect alpha-amylases from seeds or sorghum (Sorghum bicolar (L) Moench) have sequence homologies with wheat gamma-purothionins.##Amino acid sequence and disulphide-bridge pattern of three gamma-thionins from Sorghum bicolor.
DRAMP00287	RVCRRRSAGFKGLCMSDHNCAQVCLQEGWGGGNCDGVMRQCKCIRQC	47	Defensin-like protein 21 (SI alpha-2.1; Plant defensin)	Q09198	Belongs to the DEFL family	Not found	Sorghum bicolor (Sorghum) (Sorghum vulgare)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity (By similarity).
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7705336	Eur J Biochem. 1995 Mar 1;228(2):250-256.	"Nitti G, Orr¨´ S, Bloch C Jr, Morhy L, Marino G, Pucci P."	Amino acid sequence and disulphide-bridge pattern of three gamma-thionins from Sorghum bicolor.
DRAMP00288	RECQSQSHRYKGACVHDTNCASVCQTEGFSGGKCVGFRGRCFCTKHC	47	Defensin Ec-AMP-D2 (Plant defensin)	P86519	Belongs to the DEFL family	Not found	Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity. Inhibits spore germination in Fusarium oxysporum (IC(50)=102 ??g/ml). Inhibits hyphal development in P. infestans (IC(50)=50 ??g/ml). Does not induce morphological changes such as lysis of hyphae and sporangia in P. infestans.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18625284	Biochimie. 2008 Nov-Dec;90(11-12):1667-1673.	"Odintsova TI, Rogozhin EA, Baranov Y, Musolyamov AKh, Yalpani N, Egorov TA, Grishin EV."	Seed defensins of barnyard grass Echinochloa crusgalli (L.) Beauv.
DRAMP00289	RLCRVRGTRGHCFNDHGCDKVCTREGFVRGKCNGILRRCICDRQC	45	Defensin-like protein (Gamma-thionin; Plant defensin)	B5LZ79	Belongs to the DEFL family	Not found	Gymnadenia conopsea (Fragrant orchid) (Orchis conopsea)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity (By similarity).
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available##PubMed ID is not available	Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.##Submitted (JUL-2008) to UniProtKB.	"Not found##Mukherjee G, Sen SK."	"Not found##Purification, characterization, and antifungal activity of chitinase from Streptomyces venezuelae P(10)."
DRAMP00290	KTCENLSDSFKGPCIPDGNCNKHCKEKEHLLSGRCRDDFRCWCTRNC	47	Defensin Lc-def (Plant defensin)	"B3F051, P85530"	Belongs to the DEFL family	Not found	Lens culinaris subsp. culinaris (Cultivated lentil) (Lens esculenta)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	Not found	2LJ7 resolved by NMR.	"Function: Has antifungal activity against the phytopathogenic fungus Aspergillus niger VKM F-2259, but not against A.alternatia VKM F- 3047. Does not inhibit trypsin or chymotrypsin.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18468512##PubMed ID is not available	Biochem Biophys Res Commun. 2008 Jul 11;371(4):860-865.##To be Published.	"Finkina EI, Shramova EI, Tagaev AA, Ovchinnikova TV.##Shenkarev Z, Mineev K, Gizatullina A, Finkina E, Arseniev A, Ovchinnikova T."	A novel defensin from the lentil Lens culinaris seeds.##Solution structure of defensin Lc-def from germinated lentil (Lens Culinaris) seeds.
DRAMP00291	RTCESQSHRFKGACLSDTNCASVCQTEGFPAGDCKGARRRCFCVKPC	47	Defensin-like protein (Gamma-thionin homolog; Plant defensin)	A3FPF2	Belongs to the DEFL family	Not found	Nelumbo nucifera (Sacred lotus)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Has antifungal activity (By similarity).
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available##16972135	Submitted (FEB-2007) to the EMBL/GenBank/DDBJ database##Curr Microbiol. 2006 Oct;53(4):265-269.	"Not found##Mukherjee G, Sen SK."	"Not found##Purification, characterization, and antifungal activity of chitinase from Streptomyces venezuelae P(10)."
DRAMP00292	RVCESQSHGFHGLCNRDHNCALVCRNEGFSGGRCKRSRRCFCTRIC	46	Defensin-like protein (8.4 kDa sulfur-rich protein; Plant defensin)	Q07502	Belongs to the DEFL family	Not found	Glycine max (Soybean) (Glycine hispida)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Has antifungal activity (By similarity).
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8278516	Plant Physiol. 1993 Feb;101(2):699-700.	"Choi Y, Choi YD, Lee JS."	Nucleotide sequence of a cDNA encoding a low molecular weight sulfur-rich protein in soybean seeds.
DRAMP00293	RICRRRSAGFKGPCVSNKNCAQVCMQEGWGGGNCDGPLRRCKCMRRC	47	Gamma1-hordothionin (Gamma 1-H; Plant defensin)	P20230	Belongs to the DEFL family	Not found	Hordeum vulgare (Barley)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	"Gamma 1-H adopts a well-defined triple-stranded antiparallel beta-sheet (residues 1-6, 31-34, and 39-47), an alpha-helix (residues 16-28), and the corresponding connecting loops. Three disulfide bridges are located in the hydrophobic core holding together the alpha-helix and the beta-sheet and forming a cysteine-stabilized alpha-helical (CSH) motif."	1GPT resolved by NMR.	"Function: Inhibits protein translation in cell-free systems.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-21; 24-43.
Caution: Was initially thought to be a thionin."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2176600##8380707	Eur I Biochem 1990;194:533-539.##Biochemistry. 1993 Jan 19;32(2):715-724.	"Mendez E, Moreno A, Colilla F.J, Pelaez F, Limas G.G, Mendez R, Soriano F, Salinas M, de Haro C.##Bruix M, Jim?nez MA, Santoro J, Gonz?lez C, Colilla FJ, M?ndez E, Rico M."	"Primary structure and inhibition of protein synthesis in eukaryotic cell-free system of a novel thionin, gamma-hordothionin, from barley endosperm.##Solution structure of gamma 1-H and gamma 1-P thionins from barley and wheat endosperm determined by 1H-NMR: a structural motif common to toxic arthropod proteins."
DRAMP00294	YKRGGGGWGGGGGWKGGGGGGGGWKGGGGGGKGGGG	36	Glycine-rich protein GWK (Plants)	P84064	Not found	Not found	Cucumis melo (Muskmelon)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Possesses antifungal activity against a number of phytopathogenic fungi.	Fungi: Hordeum sativum and F. culmorum.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (AUG-2004) to UniProtKB	"Vassilevski AA, Egorov TA, Grishin EV."	Unknown
DRAMP00295	ADPTFGFTPLGLSEKANLQIMKAYD	25	Soybean toxin 27 kDa chain (SBTX 27 kDa chain; Plant defensin)	P86520	Not found	Not found	Glycine max (Soybean) (Glycine hispida)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Involved in plant defense. Has antifungal activity against C. sojina but not A. niger and F. solani. Does not have urease or hemagglutination activities. Does not inhibit trypsin. Injection into mice produces toxic effects such as dyspnea, tonic-clonic convulsion and death.
Subunit structure Heterodimer of a 27 kDa subunit and a 17 kDa subunit; disulfide-linked.
Tissue specificity: Expressed in seeds, leaves, roots and stem (at protein level).
Induction: In seeds, induced by jasmonate.
Post-translational modification: SBTX is known to be glycosylated but it is not known which one of its two subunits is modified; contains 5% carbohydrates.
Toxic dose: LD50 is 5.6 mg/kg by intraperitoneal injection into mice.
Miscellaneous: On the 2D-gel the determined pI of SBTX is: 8.2, its MW is: 44 kDa.
Biophysicochemical properties: pH dependence (Activity decreases below pH 5.5 and above pH 8.0)."	Fungi: C. sojina.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18328522	Toxicon. 2008 May;51(6):952-963.	"Vasconcelos IM, Morais JK, Siebra EA, Carlini CR, Sousa DO, Beltramini LM, Melo VM, Oliveira JT."	"SBTX, a new toxic protein distinct from soyatoxin and other toxic soybean [Glycine max] proteins, and its inhibitory effect on Cercospora sojina growth."
DRAMP00296	PNPKVFFDMTIGGQSAGRIVMEEYA	25	Soybean toxin 17 kDa chain (SBTX 17 kDa chain; Plant defensin)	P86548	Not found	Not found	Glycine max (Soybean) (Glycine hispida)	"Antimicrobial, Antifungal, Cytotoxic"	Protein level	Not found	Not found	None	"Function: Involved in plant defense. Has antifungal activity against C.sojina but not A.niger and F.solani. Does not have urease or hemagglutination activities. Does not inhibit trypsin. Injection into mice produces toxic effects such as dyspnea, tonic-clonic convulsion and death.
Subunit structure: Heterodimer of a 27 kDa subunit and a 17 kDa subunit; disulfide-linked.
Tissue specificity: Expressed in seeds, leaves, roots and stem (at protein level).
Induction: In seeds, induced by jasmonate.
Post-translational modification: SBTX is known to be glycosylated but it is not known which one of its two subunits is modified; contains 5% carbohydrates.
Toxic dose: LD50 is 5.6 mg/kg by intraperitoneal injection into mice.
Miscellaneous: On the 2D-gel the determined pI of SBTX is: 8.2, its MW is: 44 kDa.
Biophysicochemical properties: pH dependence (Activity decreases below pH 5.5 and above pH 8.0). "	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18328522	Toxicon. 2008 May;51(6):952-963.	"Vasconcelos IM, Morais JK, Siebra EA, Carlini CR, Sousa DO, Beltramini LM, Melo VM, Oliveira JT."	"SBTX, a new toxic protein distinct from soyatoxin and other toxic soybean [Glycine max] proteins, and its inhibitory effect on Cercospora sojina growth."
DRAMP00300	PGAGSQEERMQGQMEGQDFSHEERFLSMVRE	31	Antifungal protein 1 (Pa-AFP1; Plant defensin)	B3EWF0	Not found	Not found	Passiflora alata (Winged-stem passion flower) (Fragrant granadilla)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity against C. gloeosporioides but not against Botrytis cinerea and Fusarium sp. or against various yeasts. Has no antibacterial activity.
Subunit structure: Heterodimer; disulfide-linked.
PTM: Disulfide bonds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20955745	Peptides. 2011 May;32(5):868-874.	"Ribeiro SM, Almeida RG, Pereira CA, Moreira JS, Pinto MF, Oliveira AC, Vasconcelos IM, Oliveira JT, Santos MO, Dias SC, Franco OL."	Identification of a Passiflora alata Curtis dimeric peptide showing identity with 2S albumins.
DRAMP00303	ACGGGGGDVGSLISASLFDQMLKYRNDPRCCXXGF	35	Basic endochitinase CH1 (Plant defensin)	P29137	Belongs to the glycosyl hydrolase 19 family (Chitinase class I subfamily)	Not found	Castanea sativa (Sweet chestnut)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16653058	Plant Physiol. 1992 Oct;100(2):778-783.	"Collada C, Casado R, Fraile A, Aragoncillo C."	Basic Endochitinases Are Major Proteins in Castanea sativa Cotyledons.
DRAMP00304	SIGFDGLNDPDIVAR	15	Endochitinase 1 (Plant defensin)	P86078	Belongs to the glycosyl hydrolase 20 family (Chitinase class I subfamily)	Not found	Capsicum annuum var. annuum (Red pepper)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens. 
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	Submitted (JUL-2008) to UniProtKB	"Belchi-Navarro S, Almagro L, Pedreno M.A."	Not found
DRAMP00305	NNFYSYNAFITAAKSFPGFGTTGDTAVRGPIQISYNYNYGPCGR	44	Endochitinase 1 (Plant defensin)	P86081	Belongs to the glycosyl hydrolase 21 family (Chitinase class I subfamily)	Not found	Capsicum chinense (Scotch bonnet) (Bonnet pepper)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens. 
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	Submitted (JUL-2008) to UniProtKB	"Gomez Ros L.V, Almagro L, Ros Barcelo A, Pedreno M.A."	Not found
DRAMP00306	GPLQLSWNYNYGAAGK	16	Endochitinase 1 (Plant defensin)	P85343	Belongs to the glycosyl hydrolase 22 family (Chitinase class I subfamily)	Not found	Ginkgo biloba (Ginkgo) (Maidenhair tree)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19157640	J Plant Physiol. 2009 May 15;166(8):831-843.	"Uzal EN, G¨®mez-Ros LV, Hern¨¢ndez JA, Pedre?o MA, Cuello J, Ros Barcel¨® A."	Analysis of the soluble cell wall proteome of gymnosperms.
DRAMP00307	EQCGNQAGGXVPPNG	15	Endochitinase A1 (Plant defensin)	P21225	Belongs to the glycosyl hydrolase 23 family (Chitinase class I subfamily)	Not found	Pisum sativum (Garden pea)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
Induction: By infection with the fungal pathogen Ascochyta pisi."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	Planta 184:24-29(1991).	"Vad K, Mikkelsen JD, Collinge DB."	"Induction, purification and characterization of chitinase isolated from pea leaves inoculated with Ascochyta pisi."
DRAMP00308	AIGFDGLNDPDIVAR	15	Endochitinase 1 (Plant defensin)	P85337	Belongs to the glycosyl hydrolase 24 family (Chitinase class I subfamily)	Not found	Taxus baccata (English yew)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19157640	J Plant Physiol. 2009 May 15;166(8):831-843.	"Uzal EN, G¨®mez-Ros LV, Hern¨¢ndez JA, Pedre?o MA, Cuello J, Ros Barcel¨® A."	Analysis of the soluble cell wall proteome of gymnosperms.
DRAMP00309	MTEQKPKPSCHNVMVGNYVPTASDRAANRTLGFGLVTNIINGGLDC	46	Endochitinase 2 (CHIT 2; Plant defensin)	Q06014	Belongs to the glycosyl hydrolase 25 family (Chitinase class I subfamily)	Not found	Arachis hypogaea (Peanut)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense against chitin containing fungal and bacterial pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
Induction: By glucan and Phytophthora megasperma elicitors."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1980004	Mol Gen Genet. 1990 Dec;224(3):469-476.	"Herget T, Schell J, Schreier PH."	Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea.
DRAMP00310	SAIWFWMTPQSPK	13	Endochitinase 2 (Plant defensin)	P86079	Belongs to the glycosyl hydrolase 26 family (Chitinase class I subfamily)	Not found	Capsicum annuum var. annuum (Red pepper)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	Submitted (JUL-2008) to UniProtKB	"Gomez Ros L.V, Almagro L, Ros Barcelo A, Pedreno M.A."	Not found
DRAMP00311	GPIQISYNYNYGPCGRYCGILGVSPGDNLDCGNQR	35	Endochitinase 2 (Plant defensin)	P86082	Belongs to the glycosyl hydrolase 27 family (Chitinase class I subfamily)	Not found	Capsicum chinense (Scotch bonnet) (Bonnet pepper)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	Submitted (JUL-2008) to UniProtKB	"Sabater Jara A.B, Almagro L, Pedreno M.A."	Not found
DRAMP00312	TAGFGVFTNIINGGLECGK	19	Endochitinase 2 (Plant defensin)	P85338	Belongs to the glycosyl hydrolase 28 family (Chitinase class I subfamily)	Not found	Taxus baccata (English yew)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
PTM: Contians one disulfide bond (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19157640	J Plant Physiol. 2009 May 15;166(8):831-843.	"Uzal EN, G¨®mez-Ros LV, Hern¨¢ndez JA, Pedre?o MA, Cuello J, Ros Barcel¨® A."	Analysis of the soluble cell wall proteome of gymnosperms.
DRAMP00313	MTPQGNKPSSHDVITGRWTPSDADRAAGRVSGFGVITNIINGGLDC	46	Endochitinase 3 (CHIT 3; Plant defensin)	Q06015	Belongs to the glycosyl hydrolase 29 family (Chitinase class I subfamily)	Not found	Arachis hypogaea (Peanut)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense against chitin containing fungal and bacterial pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
Induction: Constitutively expressed at low levels."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	1980004	Mol Gen Genet. 1990 Dec;224(3):469-476.	"Herget T, Schell J, Schreier PH."	Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea.
DRAMP00314	MYDESTGYSSALK	13	Endochitinase 3 (Plant defensin)	P85355	Belongs to the glycosyl hydrolase 30 family (Chitinase class I subfamily)	Not found	Taxus baccata (English yew)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19157640	J Plant Physiol. 2009 May 15;166(8):831-843.	"Uzal EN, G¨®mez-Ros LV, Hern¨¢ndez JA, Pedre?o MA, Cuello J, Ros Barcel¨® A."	Analysis of the soluble cell wall proteome of gymnosperms.
DRAMP00315	MTPQGNKPSCHDVITNAWRPTATDSAAGRAPGYGVITNIINGGLDC	46	Endochitinase 4 (CHIT 4; Plant defensin)	Q06016	Belongs to the glycosyl hydrolase 31 family (Chitinase class I subfamily)	Not found	Arachis hypogaea (Peanut)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense against chitin containing fungal and bacterial pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
Induction: By glucan elicitor, and to a lesser extent by yeast extract, Phytophthora megasperma elicitor, UV light and dilution."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	1980004	Mol Gen Genet. 1990 Dec;224(3):469-476.	"Herget T, Schell J, Schreier PH."	Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea.
DRAMP00316	MTAQGNKPSSHDVITGRWTPSAADRAAGRVSGFGVITNIINGGLDC	46	Endochitinase 1A (CHIT 1A; Plant defensin)	Q06012	Belongs to the glycosyl hydrolase 32 family (Chitinase class I subfamily)	Not found	Arachis hypogaea (Peanut)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense against chitin containing fungal and bacterial pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
Induction: By yeast extract and dilution. Slight induction by glucan elicitor."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	1980004	Mol Gen Genet. 1990 Dec;224(3):469-476.	"Herget T, Schell J, Schreier PH."	Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea.
DRAMP00317	MTAQGNKPSSHDVITGRWTPSAADKAAGRVSGFGVITNIINGGLDC	46	Endochitinase 1B (CHIT 1B; Plant defensin)	Q06013	Belongs to the glycosyl hydrolase 33 family (Chitinase class I subfamily)	Not found	Arachis hypogaea (Peanut)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense against chitin containing fungal and bacterial pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
Induction: By yeast extract and dilution. Slight induction by glucan elicitor."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	1980004	Mol Gen Genet. 1990 Dec;224(3):469-476.	"Herget T, Schell J, Schreier PH."	Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea.
DRAMP00318	EQCGRQAGGATCPNNLCCSQYGY	23	Endochitinase B (Plant defensin)	P21227	Belongs to the glycosyl hydrolase 34 family (Chitinase class I subfamily)	Not found	Pisum sativum (Garden pea)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
Induction: By infection with the fungal pathogen Ascochyta pisi."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	PubMed ID is not availbale	Planta 184:24-29(1991).	"Vad K, Mikkelsen JD, Collinge DB."	"Induction, purification and characterization of chitinase isolated from pea leaves inoculated with Ascochyta pisi."
DRAMP00319	ENCGRQAG	8	Endochitinase (Plant defensin)	P86473	Belongs to the glycosyl hydrolase 35 family (Chitinase class I subfamily)	Not found	Actinidia chinensis (Kiwi) (Yangtao)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Defense against chitin containing fungal pathogens (By similarity).
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
Allergenic properties: Causes an allergic reaction in human.
Domian: Contains 1 chitin-binding type-1 domain."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	IgE	1553642	Tidsskr Nor Laegeforen. 1992 Jan 10;112(1):38-42.	Rygnestad T.	Suicide in Norway. Changes in the 20th century with special emphasis on the development during the last 20 years.
DRAMP00324	GIFTFEDESTSTVAPAKLYK	20	Protein PR-L1 (Plant defensin)	P83363	Belongs to the BetVI family	Not found	Lupinus luteus (European yellow lupin)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Pathogenesis-related protein. May have antifungal or antibacterial activity.
Induction: By heavy metal ions."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	J. Plant Physiol. 1999;154:703-708.	"Przymusinski R, Gwozdz E.A."	Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins.
DRAMP00325	SVFAFENEQSSTIAPARLYK	20	Protein PR-L2 (Plant defensin)	P83364	Belongs to the BetVI family	Not found	Lupinus luteus (European yellow lupin)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Pathogenesis-related protein. May have antifungal or antibacterial activity.
Induction: By heavy metal ions."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	J. Plant Physiol. 1999;154:703-708.	"Przymusinski R, Gwozdz E.A."	Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins.
DRAMP00326	GIFTFEDESTTTVAPAKLYK	20	Protein PR-L3 (Plant defensin)	P83365	Belongs to the BetVI family	Not found	Lupinus luteus (European yellow lupin)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Pathogenesis-related protein. May have antifungal or antibacterial activity.
Induction: By heavy metal ions."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	J. Plant Physiol. 1999;154:703-708.	"Przymusinski R, Gwozdz E.A."	Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins.
DRAMP00327	SVFAFQDESTSTIAQARLFI	20	Protein PR-L4 (Plant defensin)	P83366	Belongs to the BetVI family	Not found	Lupinus luteus (European yellow lupin)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Pathogenesis-related protein. May have antifungal or antibacterial activity.
Induction: By heavy metal ions."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	J. Plant Physiol. 1999;154:703-708.	"Przymusinski R, Gwozdz E.A."	Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins.
DRAMP00328	SIFAFQDESPSAIAQAKLFK	20	Protein PR-L5 (Plant defensin)	P83367	Belongs to the BetVI family	Not found	Lupinus luteus (European yellow lupin)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Pathogenesis-related protein. May have antifungal or antibacterial activity.
Induction: By heavy metal ions."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	J. Plant Physiol. 1999;154:703-708.	"Przymusinski R, Gwozdz E.A."	Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins.
DRAMP00329	GVFTFEDESTSTVAPAKLYK	20	Protein PR-L6 (Plant defensin)	P83368	Belongs to the BetVI family	Not found	Lupinus luteus (European yellow lupin)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Pathogenesis-related protein. May have antifungal or antibacterial activity.
Induction: By heavy metal ions."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not availbale	J. Plant Physiol. 1999;154:703-708.	"Przymusinski R, Gwozdz E.A."	Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins.
DRAMP00339	GADFQECMKEHSQKQHQHQG	20	Alpha-basrubrin (Fragment; Plants)	P83186	Not found	Not found	Basella alba (Malabar spinach) (Basella rubra)	"Antimicrobial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	Function: Inhibits HIV-1 reverse transcriptase and cell-free translation.	"Fungi: Botrytis cinerea, Mycosphaerella arachidicola, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11688973	Biochem Biophys Res Commun. 2001 Nov 9;288(4):765-770.	"Wang H, Ng T.B."	Novel antifungal peptides from ceylon spinach seeds.
DRAMP00340	KIMAKPSKFYEQLRGR	16	Beta-basrubin (Plants)	P83187	Not found	Not found	Basella alba (Malabar spinach) (Basella rubra)	"Antimicrobial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	Function: Possesses antifungal activity. Inhibits HIV-1 reverse transcriptase and cell-free translation.	"Fungi: Botrytis cinerea, Mycosphaerella arachidicola, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11688973	Biochem Biophys Res Commun. 2001 Nov 9;288(4):765-770.	"Wang H, Ng T.B."	Novel antifungal peptides from ceylon spinach seeds.
DRAMP00341	ANTAFVSSAHNTQKIPAGAPFNRNLRAMLADLRQNAAFAG	40	"Antifungal protein ginkbilobin-1 (Ginkbilobin, GNL; Plants)"	P83171	Not found	GNK1	Ginkgo biloba (Ginkgo) (Maidenhair tree)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral, Antifungal"	Protein level	Not found	Not found	None	Function: Also inhibits HIV-1 reverse transcriptase and proliferation of murine splenocytes.	"Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacteria: Pseudomonas aeruginosa, Escherichia coli.##Fuungi: Botrytis cinerea, Mycosphaerella arachidicola, Fusarium oxysporum, Rhizoctonia solani, Coprinus comatus,"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11118300	Biochem Biophys Res Commun. 2000 Dec 20;279(2):407-411.	"Wang H, Ng T.B."	"Ginkbilobin, a novel antifungal protein from Ginkgo biloba seeds with sequence similarity to embryo-abundant protein."
DRAMP00342	ATITVVNRCSYTVWPGALPGGGVRLDPGQRWALNMPAGTAGAAV	44	Antifungal protein R (Plant defensin)	P33044	Not found	Not found	Hordeum vulgare (Barley)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity. Inhibits the growth of Trichoderma viridae and Candida albicans.	"Fungi: Trichoderma viridae, Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1936240	FEBS Lett. 1991 Oct 7;291(1):127-131.	"Hejgaard J, Jacobsen S, Svendsen I."	Two antifungal thaumatin-like proteins from barley grain.
DRAMP00343	ATFTVINKCQYTVWAAAVPAGGGQKLDAGQTWSIXXP	37	Antifungal protein S (Plant defensin)	P33045	Not found	Not found	Hordeum vulgare (Barley)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity. Inhibits the growth of Trichoderma viridae and Candida albicans.	"Fungi: Trichoderma viridae, Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1936240	FEBS Lett. 1991 Oct 7;291(1):127-131.	"Hejgaard J, Jacobsen S, Svendsen I."	Two antifungal thaumatin-like proteins from barley grain.
DRAMP00346	AITCGQVSSALGPCAAYAKGSGTSPSAGCCSGVKRLAGLARSTADKQATCRCLKSVAGAYNAGRAAGIPSRCGVSVPYTISASVDCSKIH	90	Non-specific lipid-transfer protein Cw18 (LTP Cw-18; PKG2316; Plants)	Q43871	Belongs to the plant LTP family	CW18	Hordeum vulgare (Barley)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
Tissue specificity: Highly expressed in leaves and coleoptiles. No expression in roots.
Induction: By NaCl, abscisic acid and inoculation with the fungal pathogen E. graminis.
PTM: Contains four disulfide bonds 4-52; 14-29; 30-72; 50-86."	"Fungi: Fusarim solani (EC50=3-20¡Á10-6 M), Pseudomonas solanacearum (EC50=3-6¡Á10-7 M), Pythium aphanidermatum, Clavibacter michiganensis subsp. Sepedonicus (EC50=l-3¡Á10-7 M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	8420795##8281190	FEBS Lett. 1993 Jan 25;316(2):119-122.##Plant J. 1993 Dec;4(6):983-991.	"Molina A, Segura A, Garc¨ªa-Olmedo F.##Molina A, Garc?a-Olmedo F."	Lipid transfer proteins (nsLTPs) from barley and maize leaves are potent inhibitors of bacterial and fungal plant pathogens.##Developmental and pathogen-induced expression of three barley genes encoding lipid transfer proteins.
DRAMP00347	AISCGQVSSALSPCISYARGNGAKPPVACCSGVKRLAGAAQSTADKQAACRCLKSLATSIKGINMGKVSGVPGKCGVSVPFPISMSTDCNKVH	93	Non-specific lipid-transfer protein 3 (LTP 3; CW-19; CW-20; Plants)	Q43766	Belongs to the plant LTP family	LTP3	Hordeum vulgare (Barley)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
PTM: Contains four disulfide bonds (By similarity)."	"Fungi: Fusarim solani (EC50=3-20¡Á10-6 M), Pseudomonas solanacearum (EC50=3-6¡Á10-7 M), Pythium aphanidermatum, Clavibacter michiganensis subsp. Sepedonicus (EC50=l-3¡Á10-7 M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	8420795##8281190	FEBS Lett. 1993 Jan 25;316(2):119-122.##Plant J. 1993 Dec;4(6):983-991.	"Molina A, Segura A, Garc¨ªa-Olmedo F.##Molina A, Garc?a-Olmedo F."	Lipid transfer proteins (nsLTPs) from barley and maize leaves are potent inhibitors of bacterial and fungal plant pathogens.##Developmental and pathogen-induced expression of three barley genes encoding lipid transfer proteins.
DRAMP00348	AISCGQVSSALSPCISYARGNGAKPPAACCSGVKRLAGAAQSTADKQAACKCIKSAAGGLNAGKAAGIPSMCGVSVPYAISASVDCSKIR	90	Non-specific lipid-transfer protein 4.1 (LTP 4.1; CW-21; Plants)	Q43767	Belongs to the plant LTP family	LTP4.1	Hordeum vulgare (Barley)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
PTM: Contains four disulfide bonds 4-52; 14-29; 30-72; 50-86."	"Fungi: Fusarim solani (EC50=3-20¡Á10-6 M), Pseudomonas solanacearum (EC50=3-6¡Á10-7 M), Pythium aphanidermatum, Clavibacter michiganensis subsp. Sepedonicus (EC50=l-3¡Á10-7 M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	8420795##8281190	FEBS Lett. 1993 Jan 25;316(2):119-122.##Plant J. 1993 Dec;4(6):983-991.	"Molina A, Segura A, Garc¨ªa-Olmedo F.##Molina A, Garc?a-Olmedo F."	Lipid transfer proteins (nsLTPs) from barley and maize leaves are potent inhibitors of bacterial and fungal plant pathogens.##Developmental and pathogen-induced expression of three barley genes encoding lipid transfer proteins.
DRAMP00360	ISCQDVKQSLAPCLPYVTGRAPKPA	25	Non-specific lipid-transfer protein 1 (LTP 1; Plants)	P86527	Belongs to the plant LTP family	Not found	Nigella sativa (Black cumin)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.	Fungi: Fusarium oxysporum and Phytophthora infestans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	19621049	Bioorg Khim. 2009 May-Jun;35(3):344-349.	"Oshchepkova IuI, Veshkurova ON, Rogozhin EA, Musoliamov AKh, Smirnov AN, Odintsova TI, Egorov TsA, Grishin EV, Salikhov ShI."	Isolation of the lipid-transporting protein Ns-LTP1 from seeds of the garden fennel flower (Nigella sativa).
DRAMP00361	ITCPQVTQSLAPCVPYLISG	20	Non-specific lipid-transfer protein (LTP; Harmalin; Plants)	B3EWH4	Belongs to the plant LTP family	Not found	Peganum harmala (Syrian rue) (Harmal peganum)	"Antimicrobial, Antifungal, Antiviral, Anti-cancer"	Protein level	Not found	Not found	None	"Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Inhibits cell proliferation of cervical carcinoma cell line HeLa (IC50=2.74 ?M), gastric carcinoma cell line MGC-7 (IC50=3.13 ?M), esophageal carcinoma cell line Eca-109 (IC50=0.7 ?M) and melanoma B16 cells (IC50=1.47 ?M). Has antifungal activity. Induces caspase-dependent apoptosis in cell line Eca-109. Demonstrates inhibitory effect on HIV-1 reverse transcriptase (IC50=1.26 ?M).
Biophysicochemical properties: pH dependence (Stable between pH 4 and 10); Temperature dependence (Thermostable. Retains antifungal activity between 4 degrees Celsius and 60 degrees Celsius. Activity reduced after 30 min at 80 degrees Celsius)."	"Fungi: Penicillium digitatum (IC50=37.5 ?M), Alternaria alternata (IC50=1.5 ?M), Rhizopus stolonifer (IC50=8.44 ?M) and Magnaporthe grisea (IC50=12.19 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	PubMed ID is not available	Submitted (MAR-2012) to UniProtKB	"Ma XJ, Liu DL, Tang HS, Wang Y, Sun SR."	"Purification and characterization of a novel protein from Peganum harmala seeds with antifungal, antiproliferation and anti-HIV-1 reverse transcriptase activities."
DRAMP00369	ITCGLVASKLAPCIGYLQGAPGPSAACCGGIKSLNSAAASPADRKTACTCLKSAATSIKGINYGKAASLPRQCGVSVPYAISPNTNCNAIH	91	IWF1 (Bv-LTP1; Plant defensin)	Q43748	Belongs to the plant LTP family	IWF1'	Beta vulgaris (Sugar beet)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Also has fungicide activity.	Fungi: Cercospora beticola.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	8790287	Plant Mol Biol. 1996 Jun;31(3):539-552.	"Nielsen KK, Nielsen JE, Madrid SM, Mikkelsen JD."	New antifungal proteins from sugar beet (Beta vulgaris L.) showing homology to non-specific lipid transfer proteins.
DRAMP00370	ITCGQVTSQVAGCLSYLQRGGAPAPXXXXGIRNLXXMA	38	Antifungal protein 5 (CW-5; Plants)	P83139	Belongs to the plant LTP family	Not found	Malva parviflora (Little mallow) (Cheeseweed mallow)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses potent antifungal activity against F. graminearum but not P. infestans.
Miscellaneous: Under low salt conditions, possesses potent antifungal activity but activity is drastically reduced under high salt conditions."	Fungi: Fusarium graminearum.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11302747	Biochem Biophys Res Commun. 2001 Apr 20;282(5):1224-1228.	"Wang X, Bunkers GJ, Walters MR, Thoma RS."	Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora).
DRAMP00372	AVSCGDVTSSIAPCLSYVMGRESSPSSSCCSGVRTLNGKASSSADRRTACSCLKNMASSFRNLNMGNAASIPSKCGVSVAFPISTSVDCSKIN	93	Non-specific lipid-transfer protein 3 (Os-LTP3)	"Q2QYL3, Q42976, Q8GZV1"	Belongs to the plant LTP family	LTP110-A	Oryza sativa Japonica Group	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. May possess an antifungal activity and protect the plant against pathogens.
PTM: Problely contains four disulfide bonds 4-52; 14-29; 30-75; 50-89. "	"Pyricularia oryzae, Xanthomonas oryzae."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14659081	J Biochem Mol Biol. 2003 Nov 30;36(6):603-607.	"Ge X, Chen J, Li N, Lin Y, Sun C, Cao K."	Resistance Function: of rice lipid transfer protein LTP110.
DRAMP00373	ALSCGTVNSNLAACIGYLTQNAPLARGCCTGVTNLNNMAXTTP	43	Seed non-specific lipid transfer protein-like (ns-LTP; Plants)	P29420	Belongs to the plant LTP family	Not found	Raphanus sativus (Radish)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. This isoform inhibits the hyphal growth of several fungi in vitro.	"Fungi: Alternaria brassicola (MUCL 20297) (IC50=48 ?g/mL), Ascochyta pisi (MUCL 20164) (IC50=41 ?g/mL), Botrytis cinerea (MUCL 30158) (IC50=45 ?g/mL), Colletotrichum lindemuthianum (MUCL 9577) (IC50=25 ?g/mL), Fusarium culmorum (IMI 180420) (IC50=20 ?g/mL), Fusarium oxysporum f. sp. lycopersici (MUCL 909) (IC50=54 ?g/mL), Fusarium oxysporum f. sp. pisi (IMI 236441) (IC50=58 ?g/mL), Nectria haematococca (Collection Van Etten 26022) (IC50=100 ?g/mL), Phoma betae (MUCL 9916) (IC50=18 ?g/mL), Pyricularia oryzae (MUCL 30166) (IC50=10 ?g/mL), Trichoderma hamatum (MUCL 29736) (IC50=30 ?g/mL), Verticillium dahliae (MUCL 6963) (IC50=7 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	16653017	Plant Physiol. 1992 Oct;100(2):1055-1058.	"Terras FR, Goderis IJ, Van Leuven F, Vanderleyden J, Cammue BP, Broekaert WF."	In vitro antifungal activity of a radish (Raphanus sativus L.) seed protein homologous to non-specific lipid transfer proteins.
DRAMP00375	PAGPFRIPPRXRXEFQ	16	Antifungal protein 1 small subunit (CW-1; Plants)	P83140	Not found	Not found	Malva parviflora (Little mallow) (Cheeseweed mallow)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses very potent antifungal activity against F. graminearum.
Subunit structure: Heterodimer of a large and a small subunit.
Miscellaneous: Antimicrobial activity is not affected by salt concentration."	Fungi:##At low salt condition: Fusarium graminearum (IC50=2.5 ppm).##At high salt condition: Fusarium graminearum (IC50=10 ppm).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11118343	Biochem Biophys Res Commun. 2000 Dec 20;279(2):669-673.	"Wang X, Bunkers GJ."	Potent heterologous antifungal proteins from cheeseweed (Malva parviflora).
DRAMP00376	VAGPFRIPPLRREFQ	15	Antifungal protein 1 large subunit (CW-1; Plants)	P83141	Not found	Not found	Malva parviflora (Little mallow) (Cheeseweed mallow)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity against P. infestans but not F. graminearum.
Subunit structure: Heterodimer of a large and a small subunit.
Miscellaneous: Antimicrobial activity is not affected by salt concentration."	Fungi: Phytophthora infestans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11118343	Biochem Biophys Res Commun. 2000 Dec 20;279(2):669-673.	"Wang X, Bunkers GJ."	Potent heterologous antifungal proteins from cheeseweed (Malva parviflora).
DRAMP00377	SDYSRKRDPPQKYEEE	16	Antifungal protein 2 small subunit (CW-2; Plants)	P83142	Not found	Not found	Malva parviflora (Little mallow) (Cheeseweed mallow)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity against P. infestans but not F. graminearum.
Subunit structure: Heterodimer of a large and a small subunit. 
Miscellaneous: Antimicrobial activity is not affected by salt concentration."	Fungi: Phytophthora infestans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11118343	Biochem Biophys Res Commun. 2000 Dec 20;279(2):669-673.	"Wang X, Bunkers GJ."	Potent heterologous antifungal proteins from cheeseweed (Malva parviflora).
DRAMP00378	PEDPQRRYQEXQREXRXQQE	20	Antifungal protein 2 large subunit (CW-2; Plants)	P83143	Not found	Not found	Malva parviflora (Little mallow) (Cheeseweed mallow)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity against P. infestans but not F. graminearum.
Subunit structure: Heterodimer of a large and a small subunit.
Miscellaneous: Antimicrobial activity is not affected by salt concentration."	Fungi: Phytophthora infestans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11118343	Biochem Biophys Res Commun. 2000 Dec 20;279(2):669-673.	"Wang X, Bunkers GJ."	Potent heterologous antifungal proteins from cheeseweed (Malva parviflora).
DRAMP00379	PEDPQRRYQEEQRRE	15	Antifungal protein 3 (CW-3; Plants)	P83137	Not found	Not found	Malva parviflora (Little mallow) (Cheeseweed mallow)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity.
Miscellaneous: Antimicrobial activity is not affected by salt concentration."	Fungi: Phytophthora infestans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11302747	Biochem Biophys Res Commun. 2001 Apr 20;282(5):1224-1228.	"Wang X, Bunkers GJ, Walters MR, Thoma RS."	Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora).
DRAMP00380	DRQIDMEEQQLEKLNKQDRXPGLRYAAKQQMXTXRMG	37	Antifungal protein 4 (CW-4; Plants)	P83138	Not found	Not found	Malva parviflora (Little mallow) (Cheeseweed mallow)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity.
Miscellaneous: Antimicrobial activity is not affected by salt concentration.
Biophysicochemical properties: Temperature dependence (Thermostable). Still active after heating at 100 degrees Celsius for 20 minutes."	Fungi: Phytophthora infestans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11302747	Biochem Biophys Res Commun. 2001 Apr 20;282(5):1224-1228.	"Wang X, Bunkers GJ, Walters MR, Thoma RS."	Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora).
DRAMP00381	SGECNMYGRCPPGYCCSKFGYCGGVRAYCG	30	IWF4 (Plants)	No entry found	Not found	Not found	Beta vulgaris (Sugar beet)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Tissue specificity: IWF4 mRNA is expressed in the aerial parts of the plant only, with a constitutive expression in young and mature leaves and in young flowers."	Fungi: Cercospora beticola (IC50<2 ?g/mL).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	9008390	Plant Physiol. 1997 Jan;113(1):83-91.	"Nielsen KK, Nielsen JE, Madrid SM, Mikkelsen JD."	Characterization of a new antifungal chitin-binding peptide from sugar beet leaves.
DRAMP00382	TFPKCAPTRPPGPKPCDINNFKSKFWHIWRA	31	Datucin (Glycopeptide; Plants)	No entry found	Not found	Not found	Datura stramonium	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23193597	Biopolymers 2012; 98(4):332-337.	Mandal SM.	A Novel Hydroxyproline Rich Glycopeptide from Pericarp of Datura stramonium: Proficiently Eradicate the Biofilm of Antifungals Resistant Candida albicans.
DRAMP00383	AKCIKNGKGCREDQGPPFCCSGFCYRQVGWARGYCKNR	38	Antimicrobial peptide 1 (Mc-AMP1; knottin-type peptide; Plant defensin)	O81338	Belongs to the AMP family	Not found	Mesembryanthemum crystallinum (Common ice plant) (Cryophytum crystallinum)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Homology	Bridge	Not found	None	"Function: Possesses antifungal and antibacterial activity.
Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.
PTM: Contains three disulfide bonds 3-20; 10-24; 18-35."	"Gram-positive bacteria: Bacillus megaterium (IC50=2 ?g/mL), Sarcina lutea (IC50=50 ?g/mL).##Fungi: Alternaria brassicola (IC50=6 ?g/mL), Ascochyta pisi (IC50=6 ?g/mL), Botrytis cinerea (IC50=2 ?g/mL), Cercospora beticola (IC50=2 ?g/mL), Colletotrichum lindemuthianum (IC50=1 ?g/mL), Fusarium culmorum (IC50=3 ?g/mL), Fusarium oxysporum f. sp. Pisi (IC50=5 ?g/mL), Fusarium oxysporum f. sp. Lycopersici (IC50=10 ?g/mL), Nectria haematococca (IC50=0.5 ?g/mL), Phoma betae (IC50=6 ?g/mL), Pyrenophora tritici-repentis (IC50=20 ?g/mL), Pyricularia oryzae (IC50=0.5 ?g/mL), Rhizoctonia solani (IC50=15 ?g/mL), Verticiliium dahliae (IC50=0.5 ?g/mL), Venturia inaequalis (IC50=1 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.	"Michalowski C.B, Bohnert H.J."	Antimicrobial peptide 1 from the common ice plant.
DRAMP00386	AISCGQVSSAIGPCLSYARGQGSAPSAGCC	30	EcLTP (E. crus-galli lipid transfer protein; Plants)	No entry found	Not found	Not found	Echinochloa crusgalli L. (seeds of weed cereal barnyard grass)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Function: Possesses antifungal activity.	Fungi: Phytophthora infestans (IC50=6 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22940285	Peptides. 2012 Nov;38(1):33-40.	"Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK."	Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds.
DRAMP00387	GSGRGSCRSQCMRRHEDEPWRVQECVSQCRRRRGGGD	37	Antimicrobial peptide 1 (EcAMP1; hairpin-like peptides; Plants)	P86698	Not found	Not found	Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli)	"Antimicrobial, Antifungal"	Protein level	Alpha helix (3 helices; 20 residues)	The peptide adopts a disulfide-stabilized alpha-helical hairpin structure in aqueous solution and thus represents a novel fold among naturally occurring antimicrobial peptides.	2L2R resolved by NMR.	"Function: EcAMP1 can inhibit growth of several fungal phytopathogens. Does not destroy spores but rather inhibits hyphal growth during germination. Does not affect spore germination in A. niger, C. graminicola, D. maydis and T. album. Does not inhibit trypsin. Confocal microscopy revealed intensive EcAMP1 binding to the surface of fungal conidia followed by internalization and accumulation in the cytoplasm without disturbance of membrane integrity.
Tissue specificity: Seed."	"Fungi: Alternaria alternata (EC50=16.0¡À2.3 ?M), A. solani (EC50=14.0¡À2.1 ?M), Aspergillus niger (EC50>32 ?M), Bipolaris sorokiniana (EC50=18.2¡À2.7 ?M), Colletotrichum graminicola (EC50>10 ?M), Diplodia maydis (EC50>10 ?M), Fusarium graminearum (EC50=4.5¡À1.4 ?M), Fusarium oxysporum (EC50=8.5¡À1.6 ?M), F. solani (EC50=4.0¡À1.2 ?M), F. verticillioides (EC50=8.1¡À2.3 ?M), Phoma betae (EC50=6.0¡À1.5 ?M), Phytophthora infestans (EC50=16.3¡À2.5 ?M), Pythium debaryanum (EC50=12.0¡À1.7 ?M), P. ultimum (EC50=14.4¡À2.1 ?M), Tritirachium album (EC50>32 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22940285##21561864	Peptides. 2012 Nov;38(1):33-40.##J Biol Chem. 2011 Jul 15;286(28):25145-25153.	"Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK.##Nolde SB, Vassilevski AA, Rogozhin EA, Barinov NA, Balashova TA, Samsonova OV, Baranov YV, Feofanov AV, Egorov TA, Arseniev AS, Grishin EV."	Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds.##Disulfide-stabilized helical hairpin structure and activity of a novel antifungal peptide EcAMP1 from seeds of barnyard grass (Echinochloa crus-galli).
DRAMP00388	DRCSQQCQHHRDPDRKQQCMRECRRHQGRSD	31	Antimicrobial peptide 2 (EcAMP2; Plants)	B3EWR4	Not found	Not found	Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: EcAMP2 inhibits spore germination of P. infestans with an IC50 of 24 ?M but have no antibacterial activity.
PTM: Contains two disulfide bonds (By similarity)."	Fungi: Phytophthora infestans (IC50=24 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22940285	Peptides. 2012 Nov;38(1):33-40.	"Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK."	Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds.
DRAMP00389	DRCSQQCQHHRDPDRKQQCMRECRRH	26	EcAMP2.1 (truncated EcAMP2 without five C-terminal residues)	B3EWR4	Not found	Not found	Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: EcAMP2.1 inhibits spore germination of P. infestans with an IC50 of 24 ?M but have no antibacterial activity.
PTM: Contains two disulfide bonds (By similarity)."	Fungi: Phytophthora infestans (IC50=24 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22940285	Peptides. 2012 Nov;38(1):33-40.	"Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK."	Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds.
DRAMP00390	ANKCIIDCMKVKTTCGDECKGAGFKTGGCALPPDIMKCCHNC	42	Antimicrobial peptide 3 (ToAMP3; Cys-rich; Plant defensin)	B3EWQ3	Not found	Not found	Taraxacum officinale (Common dandelion) (Leontodon taraxacum)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity. Also active against bacterial species P. syringae, B. subtilis and X. campestris.
Tissue specificity: Expressed in flowers but not in leaves, seeds or roots (at protein level)."	Fungi: Aspergillus niger (IC50=1.2 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22640720	Peptides. 2012 Aug;36(2):266-271.	"Astafieva AA, Rogozhin EA, Odintsova TI, Khadeeva NV, Grishin EV, Egorov TsA."	Discovery of novel antimicrobial peptides with unusual cysteine motifs in dandelion Taraxacum officinale Wigg. flowers.
DRAMP00391	GGKCTVDWGGQGGGRRLPSPLFCCYKPTRICYLNQETCETETCP	44	Antimicrobial peptide 2 (ToAMP2; Cys-rich; Plant defensin)	B3EWQ2	Not found	Not found	Taraxacum officinale (Common dandelion) (Leontodon taraxacum)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity. Also active against bacterial species P. syringae, B. subtilis and X. campestris.
Tissue specificity: Expressed in flowers but not in leaves, seeds or roots (at protein level)."	"Fungi: Botrytis cinerea (IC50=5.2 ?M), Aspergillus niger (IC50=2.6 ?M), Bipolaris sorokiniana (IC50=5.2 ?M), Pythium debaryanum (IC50=2.6 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22640720	Peptides. 2012 Aug;36(2):266-271.	"Astafieva AA, Rogozhin EA, Odintsova TI, Khadeeva NV, Grishin EV, Egorov TsA."	Discovery of novel antimicrobial peptides with unusual cysteine motifs in dandelion Taraxacum officinale Wigg. flowers.
DRAMP00392	VAKCTEESGGKYFVFCCYKPTRICYMNEQKCESTCIGK	38	Antimicrobial peptide 1 (ToAMP1; Cys-rich; Plant defensin)	B3EWQ1	Not found	Not found	Taraxacum officinale (Common dandelion) (Leontodon taraxacum)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity. Also active against bacterial species P. syringae, B. subtilis and X. campestris.
Tissue specificity: Expressed in flowers but not in leaves, seeds or roots (at protein level)."	"Fungi: Botrytis cinerea (IC50=5.8 ?M), Aspergillus niger (IC50=5.6 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22640720	Peptides. 2012 Aug;36(2):266-271.	"Astafieva AA, Rogozhin EA, Odintsova TI, Khadeeva NV, Grishin EV, Egorov TsA."	Discovery of novel antimicrobial peptides with unusual cysteine motifs in dandelion Taraxacum officinale Wigg. flowers.
DRAMP00393	IQCGESCVWIPCISSAWGCSCKNKICSS	28	Hedyotide B2 (hB2; Uncyclotides; Plants)	No entry found	Not found	Not found	Hedyotis biflora (aerial tissues)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Possesses antifungal activity.	"Gram-negative bacterium: Escherichia coli (MIC>80 ?M);##Gram-positive bacteria: Streptococcus salivarius(MIC>80 ?M), Staphylococcus epidermidis (MIC>80 ?M), Streptococcus aureus (MIC>80 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21979955	J Biol Chem. 2011 Dec 30;286(52):44833-44844.	"Nguyen GK, Zhang S, Wang W, Wong CT, Nguyen NT, Tam JP."	Discovery of a linear cyclotide from the bracelet subfamily and its disulfide mapping by top-down mass spectrometry.
DRAMP00396	NLCERASLTWTGNCGNTGHCDTQCRNWESAKHGACHKRGNWKCFCYFDC	49	"Ct-AMP1 (CtAMP1, C. ternatea-antimicrobial peptide 1; Plant defensin)"	No entry found	Not found	Not found	Clitoria ternatea	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacterium: Bacillus subtilis (IC50=15 ?g/mL).##Medium A: Botrytis cinerea (IC50=20 ?g/ml), Cladosporium sphaerospermum (IC50=6 ?g/ml), Fusarium culmorum (IC50=10 ?g/ml), Leptosphaeria maculans (IC50=6 ?g/ml), Penicillium digitatum (IC50=20 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=2 ?g/ml), Verticilium albo-atrum (IC50=2 ?g/ml). NOTE: Medium B = 1/2 strength potato dextrose broth.##Medium B: Botrytis cinerea (IC50>100 ?g/ml), Cladosporium sphaerospermum (IC50=100 ?g/ml), Fusarium culmorum (IC50=50 ?g/ml), Leptosphaeria maculans (IC50=20 ?g/ml), Penicillium digitatum (IC50=80 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=80 ?g/ml), Verticilium albo-atrum (IC50>100 ?g/ml).##NOTE: Medium B = Medium A supplemented with 1 mM CaCl2 and 50 mM KCI."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7628617	FEBS Lett. 1995 Jul 17;368(2):257-262.	"Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF."	"Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae."
DRAMP00397	KFCEKPSGTWSGVCGNSGACKDQCIRLEGAKHGSCNYKPPAHRCICYYEC	50	Defensin D1 (Ns-D1; Plant defensin)	P86972	Belongs to the DEFL family	Not found	Nigella sativa (Black cumin)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Function: Antimicrobial peptide active against fungi, Gram-positive and Gram-negative bacteria. Has no effect on spore germination. Destroys spores in germinated conidia by disruption of cell walls and membranes in A. niger and B. sorokiniana. Causes vacuolization of germinated macro- and microconidia in F. oxysporum, F. graminearum and F. culmorum. Strongly inhibits growth of P. infestans on potato tubers above concentrations of 13.6 ?g/ml.
PTM: Contains four disulfide bonds."	"Fungi: Aspergillus niger (IC50=3.5 ?g/ml), Bipolaris sorokiniana (IC50=3.0 ?g/ml), Fusarium oxysporum (IC50=9.5 ?g/ml), Fusarium graminearum (IC50=6.9 ?g/ml), Fusarium culmorum (IC50=6.9 ?g/ml) and Botrytis cinerea (IC50=27.4 ?g/ml).##Gram-positive bacteria: Clavibacter michiganensis (1.4 cm) and Bacillus subtilis (1.3 cm);##Gram-negative bacteria: Pseudomonas syringae (0.9 cm), Erwinia carotovora (0.7 cm) and Escherichia coli (1.2 cm).##NOTE: Inhibition zone; Defensin concentration (11 ?g in 50 ??l)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21144761	Plant Physiol Biochem. 2011 Feb;49(2):131-137.	"Rogozhin EA, Oshchepkova YI, Odintsova TI, Khadeeva NV, Veshkurova ON, Egorov TA, Grishin EV, Salikhov SI."	Novel antifungal defensins from Nigella sativa L. seeds.
DRAMP00398	KFCEKPSGTWSGVCGNSGACKDQCIRLEGAKHGSCNYKLPAHRCICYYEC	50	Defensin D2 (Ns-D2; Plant defensin)	P86973	Belongs to the DEFL family	Not found	Nigella sativa (Black cumin)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Function: Antimicrobial peptide active against fungi, Gram-positive and Gram-negative bacteria. Has no effect on spore germination. Destroys spores in germinated conidia by disruption of cell walls and membranes in Aspergillus niger and B.sorokiniana. Causes vacuolization of germinated macro- and microconidia in Fusarium oxysporum, F.graminearum and F.culmorum. Strongly inhibits growth of P.infestans on potato tubers above concentrations of 3.4 ?g/ml.
PTM: Contains four disulfide bonds."	"Fungi: Aspergillus niger (IC50=3.5 ?g/ml), Bipolaris sorokiniana (IC50=1.8 ?g/ml), Fusarium oxysporum (IC50=5.3 ?g/ml), Fusarium graminearum (IC50=6.9 ?g/ml), Fusarium culmorum (IC50=6.9 ?g/ml) and Botrytis cinerea (IC50=13.7 ?g/ml).##Gram-positive bacteria: Clavibacter michiganensis (1.5 cm) and Bacillus subtilis (1.3 cm);##Gram-negative bacteria: Pseudomonas syringae (1.3 cm), Erwinia carotovora (0.7 cm) and Escherichia coli (1.4 cm).##NOTE: Inhibition zone; Defensin concentration (11 ?g in 50 ??l)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21144761	Plant Physiol Biochem. 2011 Feb;49(2):131-137.	"Rogozhin EA, Oshchepkova YI, Odintsova TI, Khadeeva NV, Veshkurova ON, Egorov TA, Grishin EV, Salikhov SI."	Novel antifungal defensins from Nigella sativa L. seeds.
DRAMP00399	NTCEHLADTYRGVCFTNASCDDHCKNKAHLISGTCHDWKCFCTQNC	46	Defensin-like protein 39 (Disease resistance response protein 39; Plant defensin)	Q01784	Belongs to the DEFL family	PI39	Pisum sativum (Garden pea)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Possesses antifungal activity (By similarity).
Tissue specificity: Pods.
Induction: Upon contact with the plant pathogen fungus Fusarium solani.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1799696	Mol Plant Microbe Interact. 1991 Jul-Aug;4(4):324-331.	"Chiang CC, Hadwiger LA."	The Fusarium solani-induced expression of a pea gene family encoding high cysteine content proteins.
DRAMP00400	NLCERASLTWTGNCGNTGHCDTQCRNWESAKHGACHKRGNWKCFCYFNC	49	"Defensin-like protein 1 (Defensin AMP1, CtAMP1; Plant defensin)"	Q7M1F2	Belongs to the DEFL family	Not found	Clitoria ternatea (Butterfly pea)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Possesses antimicrobial activity sensitive to inorganic cations. Binds specifically to the fungal plasma membrane. Has no inhibitory effect on insect gut alpha-amylase.
PTM: Contains four disulfide bonds (By similarity)."	"Fungi: Botrytis cinerea (IC50=20 ?g/ml), Cladosporium sphaerospermum (IC50=6 ?g/ml), Fusarium culmorum (IC50=10 ?g/ml), Leptosphaeria maculans (IC50=6 ?g/ml), Penicillium digitatum (IC50=20 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=2 ?g/ml), Verticilium albo-atrum (IC50=2 ?g/ml), Neurospora crassa (IC50<0.3 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	fungal plasma membrane	7628617##10656585	FEBS Lett. 1995 Jul 17;368(2):257-262.##Mol Plant Microbe Interact. 2000 Jan;13(1):54-61.	"Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF.##Thevissen K, Osborn RW, Acland DP, Broekaert WF."	"Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae.##Specific binding sites for an antifungal plant defensin from Dahlia (Dahlia merckii) on fungal cells are required for antifungal activity."
DRAMP00401	DSECLKEYGGDVGFPFCAPRIFPTICYTRCRENKGAKGGRCIWGEGTNVKCLCDYCNDSPFDQ	63	Defensin-like protein 2 (MTI-2; Trypsin inhibitor 2; Plant defensin)	P26780	Belongs to the DEFL family	Not found	Sinapis alba (White mustard) (Brassica hirta)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Inhibits bovine beta-trypsin and alpha-chymotrypsin on a 1:1 molar basis.
PTM: Problely contains four disulfide bonds 4-56; 17-41; 26-51; 30-53."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7750566##1451776	FEBS Lett. 1995 May 8;364(2):179-181.##FEBS Lett. 1992 Apr 13;301(1):10-14.	"Ceci LR, Spoto N, de Virgilio M, Gallerani R.##Menegatti E, Tedeschi G, Ronchi S, Bortolotti F, Ascenzi P, Thomas RM, Bolognesi M, Palmieri S."	"The gene coding for the mustard trypsin inhibitor-2 is discontinuous and wound-inducible.##Purification, inhibitory properties and amino acid sequence of a new serine proteinase inhibitor from white mustard (Sinapis alba L.) seed."
DRAMP00403	GIFSSRKCKTPSKTFKGICTRDSNCDTSCRYEGYPAGDCKGIRRRCMCSKPC	52	Defensin D2 (So-D2; Antimicrobial peptide D2; Plant defensin)	P81571	Belongs to the DEFL family	Not found	Spinacia oleracea (Spinach)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens.
Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots.
Developmental stage: Present throughout the life of the leaf.
PTM: Contains four disulfide bonds (By similarity)."	Gram-positive bacterium: Clavibacter michiganensis;##Gram-negative bacterium: Ralstonia solanacearum.##Fungi: Fusarium culmorum.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9762899	FEBS Lett. 1998; 435: 159-162.	"Segura A, Moreno M, Molina A, Garc?a-Olmedo F."	Novel defensin subfamily from spinach (Spinacia oleracea).
DRAMP00404	GIFSSRKCKTVSKTFRGICTRNANC	25	Defensin D3 (So-D3; Antimicrobial peptide D3; Plant defensin)	P81570	Belongs to the DEFL family	Not found	Spinacia oleracea (Spinach)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens.
Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots.
Developmental stage: Present throughout the life of the leaf."	Fungi: Fusarium spp.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9762899	FEBS Lett. 1998; 435: 159-162.	"Segura A, Moreno M, Molina A, Garcia-Olmedo F."	Novel defensin subfamily from spinach (Spinacia oleracea).
DRAMP00405	MFFSSKKCKTVSKTFRGPCVRNA	23	Defensin D4 (So-D4; Antimicrobial peptide D4; Plant defensin)	P81569	Belongs to the DEFL family	Not found	Spinacia oleracea (Spinach)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens.
Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots.
Developmental stage: Present throughout the life of the leaf."	Fungi: Fusarium spp.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9762899	FEBS Lett. 1998; 435: 159-162.	"Segura A, Moreno M, Molina A, Garcia-Olmedo F."	Novel defensin subfamily from spinach (Spinacia oleracea).
DRAMP00406	MFFSSKKCKTVXKTFRGPCVRNAN	24	Defensin D5 (So-D5; Antimicrobial peptide D5; Plant defensin)	P81568	Belongs to the DEFL family	Not found	Spinacia oleracea (Spinach)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens.
Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots.
Developmental stage: Present throughout the life of the leaf."	"Gram-positive bacterium: Clavibacter michiganensis;##Gram-negative bacterium: Ralstonia solanacearum.##Fungi: Fusarium culmorum, Fusarium solani, Bipolaris maydis and Colletotrichum lagenarium."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9762899	FEBS Lett. 1998; 435: 159-162.	"Segura A, Moreno M, Molina A, Garcia-Olmedo F."	Novel defensin subfamily from spinach (Spinacia oleracea).
DRAMP00407	GIFSNMYXRTPAGYFRGPXGYXXN	24	Defensin D6 (So-D6; Antimicrobial peptide D6; Plant defensin)	P81567	Belongs to the DEFL family	Not found	Spinacia oleracea (Spinach)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens.
Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots.
Developmental stage: Present throughout the life of the leaf."	Gram-positive bacterium: Clavibacter michiganensis (EC50=1 ?M);##Gram-negative bacterium: Ralstonia solanacearum (EC50=6 ?M).##Fungi: Fusarium solani (EC50=11 ?M). 	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9762899	FEBS Lett. 1998; 435: 159-162.	"Segura A, Moreno M, Molina A, Garcia-Olmedo F."	Novel defensin subfamily from spinach (Spinacia oleracea).
DRAMP00408	GIFSSRKCKTPSKTFKGYCTRDSNCDTSCRYEGYPAGD	38	Defensin D7 (So-D7; Antimicrobial peptide D7; Plant defensin)	P81573	Belongs to the DEFL family	Not found	Spinacia oleracea (Spinach)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens.
Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots.
Developmental stage: Present throughout the life of the leaf."	Fusarium spp.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9762899	FEBS Lett. 1998; 435: 159-162.	"Segura A, Moreno M, Molina A, Garcia-Olmedo F."	Novel defensin subfamily from spinach (Spinacia oleracea).
DRAMP00409	KTCENLADTY	10	Defensin-like protein (Sesquin; Plant defensin)	P84868	Belongs to the DEFL family	Not found	Vigna unguiculata subsp. sesquipedalis (Yard-Long bean) 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal and antibacterial activity. Has mitogenic activity towards murine splenocytes. Inhibits the proliferation of M1 leukemia and MCF-7 breast cancer cells in vitro. Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase.	"Fungi: Botrytis cinerea (IC50=2.5¡À0.01 ?M), Fusarium oxysporum (IC50=1.4¡À0.02 ?M), Mycosphaerella arachidicola (IC50=0.15¡À0.002 ?M).##Gram-positive bacteria: Bacillus megaterium, Mycobacterium phlei;##Gram-negative bacteria: Escherichia coli, Proteus vulgaris."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15949629	Peptides. 2005 Jul;26(7):1120-1126.	"Wong JH, Ng TB"	"Sesquin, a potent defensin-like antimicrobial peptide from ground beans with inhibitory activities toward tumor cells and HIV-1 reverse transcriptase."
DRAMP00410	QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHK	44	Defensin-like protein 1 (Bn-AFP1; Plant defensin)	"P69240, P30225, Q41163"	Belongs to the DEFL family	AFP1	Brassica napus (Rape)	"Antimicrobial, Antifungal"	Protein level	Rich	Not found	None	"Function: Possesses antifungal activity sensitive to inorganic cations.
Subunit structure: Forms oligomers in its native state.
PTM: Problely contains one disulfide bond."	"Fungi: Alternaria brassicola (IC50=3 ?g/ml), Botrytis cinerea (IC50=1.50 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Fusarium oxysporum f.sp.lycopersici (IC50=1.80 ?g/ml), Pyricularia oryzae (IC50=0.25 ?g/ml), Verticiliium dahliae (IC50=0.80 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8422949	FEBS Lett. 1993 Feb 1;316(3):233-240.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF."	A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
DRAMP00411	QKLCERPSGTWSGVCGNNNACKN	23	Defensin-like protein 2 (Bn-AFP2; Plant defensin)	P30226	Belongs to the DEFL family	Not found	Brassica napus (Rape)	"Antimicrobial, Antifungal"	Protein level	Rich	Not found	None	"Function: Possesses antifungal activity sensitive to inorganic cations.
Subunit structure: Forms oligomers in its native state."	"Fungi: Alternaria brassicola (IC50=75 ?g/ml), Botrytis cinerea(IC50> 100 ?g/ml), Fusarium culmorum (IC50=38 ?g/ml), Fusarium oxysporum f.sp.lycopersici (IC50=42 ?g/ml), Pyricularia oryzae (IC50=3 ?g/ml), Verticiliium dahliae (IC50=15 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8422949	FEBS Lett. 1993 Feb 1;316(3):233-240.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF."	A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
DRAMP00412	QKLCERPSGTWSGVCGNNNACKNQCIN	27	Defensin-like protein 1 (Br-AFP1; Plant defensin)	P30227	Belongs to the DEFL family	Not found	Brassica rapa (Turnip)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Possesses antifungal activity sensitive to inorganic cations.
Subunit structure: Forms oligomers in its native state."	"Fungi: Alternaria brassicola (IC50=3 ?g/ml), Botrytis cinerea(IC50=1.5 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Fusarium oxysporum f.sp. lycopersici (IC50=1.8 ?g/ml), Pyricularia oryzae (IC50=0.25 ?g/ml), Verticiliium dahliae (IC50=0.8 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8422949	FEBS Lett. 1993 Feb 1;316(3):233-240.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF."	A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
DRAMP00413	QKLCERPSGTXSGVCGNNNACKNQCIR	27	Defensin-like protein 2 (Br-AFP2; Plant defensin)	P30228	Belongs to the DEFL family	Not found	Brassica rapa (Turnip)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Function: Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).	"Fungi: Alternaria brassicola (IC50=75 ?g/ml), Botrytis cinerea(IC50>100 ?g/ml), Fusarium culmorum (IC50=38 ?g/ml), Fusarium oxysporum f.sp. lycopersici (IC50=42 ?g/ml), Pyricularia oryzae (IC50=3 ?g/ml), Verticiliium dahliae (IC50=15 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8422949	FEBS Lett. 1993 Feb 1;316(3):233-240.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF."	A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
DRAMP00415	QKLCQRPSGTWSGVCGNNNACKNQCIRLEKARHGSCNYVFPAHKCICYFPC	51	Raphanus sativus Antifungal Protein 2 (Rs-AFP2; Plant defensin)	"P30230, Q003I2"	Belongs to the DEFL family	AFP2	Raphanus sativus (Radish)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"PTM: Contains four disulfide bonds 4-51;15-36;21-45;25-47, and Pyrrolidone carboxylic acid at position 1."	"Fungi: Alternaria brassicola (IC50=2 ?g/ml), Ascochyta pisi (IC50=4 ?g/ml), Botrytis cinerea (IC50=2 ?g/ml), Cercospora beticola (IC50=2 ?g/ml), Colletotrichum lindemuthianum (IC50=3 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Fusarium oxysporum f.sp.lycopersici (IC50=2 ?g/ml), Fusarium oxysporum f.sp.pisi (IC50=2 ?g/ml), Mycosphaerella fijiensis var.fijiensis (IC50=1.5 ?g/ml), Nectria haematococca (IC50=2 ?g/ml), Phoma betae (IC50=1 ?g/ml), Phytophthora infestans (IC50=25 ?g/ml), Pyrenophora tritici-repentis (IC50=1.5 ?g/ml), Pyricularia oryzae (IC50=0.4 ?g/ml), Rhizoctonia solani (IC50>100 ?g/ml), Sclerotinia sclerotiorum (IC50>100 ?g/ml), Septoria nodorum (IC50=15 ?g/ml), Trichoderma hamatum (IC50=2 ?g/ml), Verticillium dahliae (IC50=1.5 ?g/ml), Venturia inaequalis (IC50=25 ?g/ml). [NOTE: Synthetic low ionic strength growth medium]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7780308	Plant Cell. 1995 May;7(5):573-588.	"Terras FR, Eggermont K, Kovaleva V, Raikhel NV, Osborn RW, Kester A, Rees SB, Torrekens S, Van Leuven F, Vanderleyden J, et al."	Small cysteine-rich antifungal proteins from radish: their role in host defense.
DRAMP00418	QKLCERPSGTWSGVCGNNGACRNQCIRLERARHGSCNYVFPAHKCICYFPC	51	Hc-AFP4 (Plant defensin)	No entry found	Not found	Hc-AFP4	Heliophila coronopifolia (South African Brassicaceae species)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Has antifungal activity. 
PTM: Contains four disulfide bonds."	"Fungi: Botrytis cinerea (IC50=15-20 ?g/ml), Fusarium solani (IC50=5-10 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22032337	BMC Res Notes. 2011 Oct 28;4:459.	"de Beer A, Vivier MA."	Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes.
DRAMP00419	RYCERSSGTWSGVCGNTDKCSSQCQRLEGAAHGSCNYVFPAHKCICYYPC	50	Hc-AFP3 (Plant defensin)	No entry found	Not found	Hc-AFP3	Heliophila coronopifolia (South African Brassicaceae species)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Has antifungal activity. 
PTM: Contains four disulfide bonds."	"Fungi: Botrytis cinerea (IC50=20-25 ?g/ml), Fusarium solani (IC50>25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22032337	BMC Res Notes. 2011 Oct 28;4:459.	"de Beer A, Vivier MA."	Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes.
DRAMP00420	QKLCERPSGTWSGVCGNNNACRNQCINLEKARHGSCNYVFPAHKCICYFPC	51	Hc-AFP2 (Plant defensin)	No entry found	Not found	Hc-AFP2	Heliophila coronopifolia (South African Brassicaceae species)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Has antifungal activity. 
PTM: Contains four disulfide bonds."	"Fungi: Botrytis cinerea (IC50=10-15 ?g/ml), Fusarium solani (IC50=10-15 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22032337	BMC Res Notes. 2011 Oct 28;4:459.	"de Beer A, Vivier MA."	Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes.
DRAMP00421	RYCERSSGTWSGVCGNSGKCSNQCQRLEGAAHGSCNYVFPAHKCICYYPC	50	Hc-AFP1 (Plant defensin)	No entry found	Not found	Hc-AFP1	Heliophila coronopifolia (South African Brassicaceae species)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Has antifungal activity. 
PTM: Contains four disulfide bonds."	"Fungi: Botrytis cinerea (IC50>25 ?g/ml), Fusarium solani (IC50>25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22032337	BMC Res Notes. 2011 Oct 28;4:459.	"de Beer A, Vivier MA."	Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes.
DRAMP00424	QKLCERSSGTWSGVCGNNNACKNQCINLEGARHGSCNYVFPYHRCICYFPC	50	Br-AFP1 (Defensin 1.2; Plant defensin)	No entry found	Not found	Not found	Brassica rapa subsp. Chinensis	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8422949##7628617	FEBS Lett. 1993 Feb 1;316(3):233-240.##FEBS Lett. 1995 Jul 17;368(2):257-262.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF."	"A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae."
DRAMP00426	DGVKLCDVPSGTWSGHCGSSSKCSQQCKDREHFAYGGACHYQFPSVKCFCKRQC	54	Defensin-like protein 1 (Hs-AFP1; Plant defensin)	"Q7M1F4, P0C8Y5"	Belongs to the DEFL family	Not found	Heuchera sanguinea (Coralbells)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Possesses antifungal activity insensitive to inorganic cations. Causes germ tubes and hyphae to swell and form multiple hyphal buds. Binds to the plasma membrane of the fungus. Has no inhibitory effect on insect gut alpha-amylase.
PTM: Contains four disulfide bonds (By similarity)."	"Fungi: Botrytis cinerea (IC50=6 ?g/ml), Cladosporium sphaerospermum (IC50=1 ?g/ml), Fusarium culmorum (IC50=1 ?g/ml), Leptosphaeria maculans (IC50=25 ?g/ml), Penicillium digitatum (IC50=1?g/ml), Trichoderma viride (IC50=15 ?g/ml), Septoria tritiei (IC50=0.5 ?g/ml), Verticillium albo-atrum (IC50=0.5 ?g/ml), Neurospora crassa (IC50=12 ?g/ml). "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	"chitin, mannan, galactocerebrosides, and sphingomyelin (Mycopathologia. 1998-1999;144:87-91)"	7628617##9405418##16284838	FEBS Lett. 1995 Jul 17;368(2):257-262.##J Biol Chem. 1997 Dec 19;272(51):32176-32181.##Mycopathologia. 1998-1999;144(2):87-91.	"Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF.##Thevissen K, Osborn RW, Acland DP, Broekaert WF.##De Lucca AJ, Jacks TJ, Broekaert WJ."	"Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae.##Specific, high affinity binding sites for an antifungal plant defensin on Neurospora crassa hyphae and microsomal membranes.##Fungicidal and binding properties of three plant peptides."
DRAMP00427	AICKKPSKFFKGACGRDADCEKACDQENWPGGVCVPFLRCECQRSC	46	Defensin-like protein AX1 (Antifungal protein AX1; Plant defensin)	P81493	Belongs to the DEFL family	Not found	Beta vulgaris (Sugar beet)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	"Function: Strong inhibiting activity against C. beticola and other filamentous fungi. Little or no effect against bacteria.
Tissue specificity: Leaves and flowers.
PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity)."	"Fungi: Cercospora beticola, Botrytis cinerea, Fusarium graminearum, Bipolaris maydis."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7655063	Mol Plant Microbe Interact. 1995 May-Jun;8(3):424-434.	"Kragh KM, Nielsen JE, Nielsen KK, Dreboldt S, Mikkelsen JD."	Characterization and localization of new antifungal cysteine-rich proteins from Beta vulgaris.
DRAMP00428	ATCRKPSMYFSGACFSDTNCQKACNREDWPNGKCLVGFKCECQRPC	46	Defensin-like protein AX2 (Antifungal protein AX2; Cys-rich; Plant defensin)	"P82010, P81510"	Belongs to the DEFL family	Not found	Beta vulgaris (Sugar beet)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	"Function: Strong inhibiting activity against C. beticola and other filamentous fungi. Little or no effect against bacteria.
Tissue specificity: Leaves and flowers.
PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity)."	"Fungi: Cercospora beticola, Botrytis cinerea, Fusarium graminearum, Bipolaris maydis."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7655063	Mol Plant Microbe Interact. 1995 May-Jun;8(3):424-434.	"Kragh KM, Nielsen JE, Nielsen KK, Dreboldt S, Mikkelsen JD."	Characterization and localization of new antifungal cysteine-rich proteins from Beta vulgaris.
DRAMP00429	LCNERPSQTWSGNCGNTAHCDKQCQDWEKASHGACHKRENHWKCFCYFNC	50	Aesculus hippocastanum antimicrobial protein 1 (Ah-AMP1; Cys-rich; Plant defensin)	Q7M1F3	Belongs to the DEFL family	Not found	Aesculus hippocastanum (Horse chestnut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Combine helix and strand structure	Not found	1BK8 resolved by NMR.	"Function: Possesses antimicrobial activity sensitive to inorganic cations. Binds specifically to the fungal plasma membrane. Has no inhibitory effect on insect gut alpha-amylase.
PTM: Contains four disulfide bonds 2-50; 14-35; 20-44; 24-46 (By similarity)."	"Gram-positive bacterium: Bacillus subtilis (IC50=100 ?g/mL).##Fungi: [MA: Botrytis cinerea (IC50=25 ?g/mL), Cladosporium sphaerospermum (IC50=0.5 ?g/mL), Fusarium culmorum (IC50=12 ?g/mL), Leptosphaeria maculans (IC50=0.5 ?g/mL), Penicillium digitatum (IC50=6 ?g/mL), Trichoderma viride (IC50>100 ?g/mL), Septoria tritiei (IC50=0.5 ?g/mL), Verticilium albo-atrum (IC50=6 ?g/mL). MA+: Botrytis cinerea (IC50>100 ?g/mL), Cladosporium sphaerospermum (IC50=12 ?g/mL), Fusarium culmorum (IC50>100 ?g/mL), Leptosphaeria maculans (IC50=6 ?g/mL), Penicillium digitatum (IC50=25 ?g/mL), Trichoderma viride (IC50>100 ?g/mL), Septoria tritiei (IC50=1.5 ?g/mL), Verticilium albo-atrum (IC50>100 ?g/mL)].##NOTE: MA+ = MA supplemented with 1 mM CaCl2 and 50 mM KCl."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Binds specifically to the fungal plasma membrane.	7628617##10591099##10656585	FEBS Lett. 1995 Jul 17;368(2):257-262.##Proteins. 1999 Nov 15;37(3):388-403.##Mol Plant Microbe Interact. 2000 Jan;13(1):54-61.	"Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF.##Fant F, Vranken WF, Borremans FA.##Thevissen K, Osborn RW, Acland DP, Broekaert WF."	"Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae.##The three-dimensional solution structure of Aesculus hippocastanum antimicrobial protein 1 determined by 1H nuclear magnetic resonance.##Specific binding sites for an antifungal plant defensin from Dahlia (Dahlia merckii) on fungal cells are required for antifungal activity."
DRAMP00432	RVCRRRSAGFKGVCMSDHNCAQVCLQEGYGGGNCDGIMRQCKCIRQC	47	Defensin-like protein 1 (Gamma-zeathionin-1; Plant defensin)	P81008	Belongs to the DEFL family	Not found	Zea mays (Maize)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Sodium channel blocker.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Protein Pept. Lett. 1996;3:267-274.	"Castro M.S, Fontes W, Morhy L, Bloch C. Jr."	Complete amino acid sequences of two gamma-thionins from maize (Zea mays L.) seeds.
DRAMP00433	RVCMGKSQHHSFPCISDRLCSNECVKEDGGWTAGYCHLRYCRCQKAC	47	Defensin-like protein 2 (Gamma-zeathionin-2; Plant defensin)	P81009	Belongs to the DEFL family	Not found	Zea mays (Maize)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Sodium channel blocker.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Protein Pept. Lett. 1996;3:267-274.	"Castro M.S, Fontes W, Morhy L, Bloch C. Jr."	Complete amino acid sequences of two gamma-thionins from maize (Zea mays L.) seeds.
DRAMP00434	KICRRRSAGFKGPCMSNKNCAQVCQQEGWGGGNCDGPFRRCKCIRQC	47	Defensin-like protein 1 (Gamma-1-purothionin; Plant defensin)	P20158	Belongs to the DEFL family	Not found	Triticum aestivum (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	"Gamma 1-P has a well-defined triple-stranded antiparallel beta-sheet (residues 1-6, 31-34, and 39-47), an alpha-helix (residues 16-28), and the corresponding connecting loops. Three disulfide bridges are located in the hydrophobic core holding together the alpha-helix and the beta-sheet and forming a cysteine-stabilized alpha-helical (CSH) motif."	None	PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2226781##8380707	FEBS Lett. 1990 Sep 17;270(1-2):191-194.##Biochemistry. 1993 Jan 19;32(2):715-724.	"Colilla FJ, Rocher A, Mendez E.##Bruix M, Jim?nez MA, Santoro J, Gonz?lez C, Colilla FJ, M?ndez E, Rico M. "	Gamma-Purothionins: amino acid sequence of two polypeptides of a new family of thionins from wheat endosperm.##Solution structure of gamma 1-H and gamma 1-P thionins from barley and wheat endosperm determined by 1H-NMR: a structural motif common to toxic arthropod proteins.
DRAMP00435	KVCRQRSAGFKGPCVSDKNCAQVCLQEGWGGGNCDGPFRRCKCIRQC	47	Defensin-like protein 2 (Gamma-2-purothionin; Plant defensin)	P20159	Belongs to the DEFL family	Not found	Triticum aestivum (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2226781	FEBS Lett. 1990 Sep 17;270(1-2):191-194. 	"Colilla FJ, Rocher A, Mendez E. "	Gamma-Purothionins: amino acid sequence of two polypeptides of a new family of thionins from wheat endosperm. 
DRAMP00438	KSTCKAESNTFPGLCITKPPCRKACLSEKFTDGKCSKILRRCICYKPCVFDGKMIQTGAENLAEEAETLAAALLEEEMMDN	81	Defensin-like protein 1 (Gamma-thionin 1; Plant defensin)	O24115	Belongs to the DEFL family	THIO1	Nicotiana paniculata	"Antimicrobial, Antifungal"	Transcript level	Bridge	Not found	None	PTM: Contains four disulfide bonds 4-48; 15-35; 21-42; 25-44.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Plant Gene Register PGR97-132.	"Komori T, Yamada S, Imaseki H."	A cDNA clone for gamma-thionin from Nicotiana paniculata.
DRAMP00439	RTCESQSHRFHGTCVRESNCASVCQTEGFIGGNCRAFRRRCFCTRNC	47	Defensin-like protein (Gamma-thionin homolog PPT; Plant defensin)	Q40901	Belongs to the DEFL family	Not found	Petunia integrifolia (Violet-flowered petunia)	"Antimicrobial, Antifungal"	Transcript level	Bridge	Not found	None	"Function: May be involved in the defense of the pistil against pathogen infection.
Tissue specificity: Predominantly expressed in the pistil during all stages of flower development.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-21; 24-43 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7948892	Plant Mol Biol. 1994 Oct;26(1):459-464.	"Karunanandaa B, Singh A, Kao TH."	Characterization of a predominantly pistil-expressed gene encoding a gamma-thionin-like protein of Petunia inflata.
DRAMP00440	NEMGGPLVVEARTCESQSHKFKGTCLSDTNCANVCHSERFSGGKCRGFRRRCFCTTHC	58	Defensin SD2 (Plant defensin)	P82659	Belongs to the DEFL family	SD2	Helianthus annuus (Common sunflower)	"Antimicrobial, Antifungal"	Transcript level	Bridge	Not found	None	"Function:May play a protective role in flowers by protecting the reproductive organs from potential pathogen attack.
Tissue specificity: Highest expression in flowers and to a lesser extent in leaves. Lower levels in hypocotyls. No expression in roots and cotyledons.
Developmental stage:Expressed progressively during flower development reaching the highest level in the mature fertilized flower stage.
PTM: Problely contains four disulfide bonds 14-57; 25-44; 31-52; 35-54."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Plant Physiol. Biochem. 2000;38:253-258.	"Urdangarin M.C, de la Canal L."	A defensin gene expressed in sunflower inflorescence.
DRAMP00441	RTCQSQSHKFKGACFSDTNCDSVCRTENFPRGQCNQHHVERKCYCERDC	49	Defensin Tk-AMP-D1 (Plant defensin)	P84963	Belongs to the DEFL family	Not found	Triticum kiharae (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Has weak antifungal activity, but not against A. consortiale Botrytis cinerea, H. sativum, F. culmorum, C. graminicola and D. maydis.
PTM: Contains four disulfide bonds 3-49; 14-34; 20-43; 24-45 (By similarity)."	Fungi: Fusarium graminearum and Fusarium verticillioides (MIC<30 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17321030##18625284	Biochimie. 2007 May;89(5):605-612.##Biochimie. 2008 Nov-Dec;90(11-12):1667-1673.	"Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV.##Odintsova TI, Rogozhin EA, Baranov Y, Musolyamov AKh, Yalpani N, Egorov TA, Grishin EV."	Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes.##Seed defensins of barnyard grass Echinochloa crusgalli (L.) Beauv.
DRAMP00442	RDCESDSHKFHGACFSDTNCANVCQTEGFTAGKCVGVQRHCHCTKDC	47	Defensin Tk-AMP-D1.1 (Plant defensin)	P84965	Belongs to the DEFL family	Not found	Triticum kiharae (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Plant defense peptide (By similarity).
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17321030	Biochimie. 2007 May;89(5):605-612.	"Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV."	Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. 
DRAMP00443	RTCESQSHKFKGPCFSDSNCATVCRTENFPRGQCNQHHVERKCYCERSC	49	Defensin Tk-AMP-D2 (Plant defensin)	P84968	Belongs to the DEFL family	Not found	Triticum kiharae (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Plant defense peptide (By similarity).
PTM: Contains four disulfide bonds 3-49; 14-34; 20-43; 24-45 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17321030	Biochimie. 2007 May;89(5):605-612.	"Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV."	Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. 
DRAMP00444	RDCKSDSHKFHGACFSDTNCANVCQTEGFTRGKCDGIHCHCIKDC	45	Defensin Tk-AMP-D3 (Plant defensin)	P84970	Belongs to the DEFL family	Not found	Triticum kiharae (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Plant defense peptide (By similarity).
PTM: Contains four disulfide bonds 3-45; 14-34; 20-39; 24-41 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17321030	Biochimie. 2007 May;89(5):605-612.	"Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV."	Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. 
DRAMP00445	RDCTSQSHKFVGLCLSDRNCASVCLTEYFTGGKCDHRRCVCTKGC	45	Defensin Tk-AMP-D4 (Plant defensin)	P84971	Belongs to the DEFL family	Not found	Triticum kiharae (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Plant defense peptide (By similarity).
PTM: Contains four disulfide bonds 3-45; 14-34; 20-39; 24-41 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17321030	Biochimie. 2007 May;89(5):605-612.	"Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV."	Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. 
DRAMP00446	RECRSESKKFVGLCVSDTNCASVCLTERFPGGKCDGYRRCFCTKDC	46	Defensin Tk-AMP-D5 (Plant defensin)	P84966	Belongs to the DEFL family	Not found	Triticum kiharae (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Plant defense peptide (By similarity).
PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity). "	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17321030	Biochimie. 2007 May;89(5):605-612.	"Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV."	Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. 
DRAMP00447	RDCRSQSKTFVGLCVSDTNCASVCLTEHFPGGKCDGYRRCFCTKDC	46	Defensin Tk-AMP-D6 (Plant defensin)	P84967	Belongs to the DEFL family	Not found	Triticum kiharae (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Plant defense peptide (By similarity).
PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity). "	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17321030	Biochimie. 2007 May;89(5):605-612.	"Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV."	Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. 
DRAMP00448	RECRSQSKQFVGLCVSDTNCASVCLTEHFPGGKCDGYRRCFCTKDC	46	Defensin Tk-AMP-D6.1 (Plant defensin)	P84969	Belongs to the DEFL family	Not found	Triticum kiharae (Wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Plant defense peptide (By similarity).
PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity). "	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17321030	Biochimie. 2007 May;89(5):605-612.	"Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV."	Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. 
DRAMP00449	RTCQSQSHKFKGACFSDTNCASVCRTENFPRGQCNQHHVERKCYCERDC	49	Defensin Tm-AMP-D1.2 (Plant defensin)	P84964	Belongs to the DEFL family	Not found	Triticum monococcum (Einkorn wheat)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Plant defense peptide (By similarity).
PTM: Contains four disulfide bonds 3-49; 14-34; 20-43; 24-45 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17321030	Biochimie. 2007 May;89(5):605-612.	"Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV."	Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. 
DRAMP00451	QKLCARPSGTWSSGNCRNNNACRNFCIKLEKSRHGSCNIPFPSNKCICYFPC	52	Defensin-like protein 2B (AFP2b; M2B; Plant defensin)	Q10989	Belongs to the DEFL family	Not found	Sinapis alba (White mustard)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Possesses antifungal activity sensitive to inorganic cations. 
Subunit structure: Forms oligomers in its native state.
PTM: Contains four disulfide bonds 4-52; 16-37; 22-46; 26-48 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8836771	Int J Pept Protein Res. 1996 Jun;47(6):437-446.	"Neumann GM, Condron R, Polya GM."	Purification and mass spectrometry-based sequencing of yellow mustard (Sinapis alba L.) 6 kDa proteins. Identification as antifungal proteins.
DRAMP00452	KICEALSGNFKGLCLSSRDCGNVCRREGFTDGSCIGFRLQCFCTKPCA	48	Defensin J1-1 (Plant defensin)	Q43413	Belongs to the DEFL family	Not found	Capsicum annuum (Bell pepper)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Tissue specificity: Expressed in orange and red ripe fruit and to a lesser extent in mature, green fruit. Present in trace in young, green fruit.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43."	"Fungi: Fusarium oxysporum, Botrytis cinerea."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8883377	Plant Physiol. 1996 Oct;112(2):615-622.	"Meyer B, Houln? G, Pozueta-Romero J, Schantz ML, Schantz R."	Fruit-specific expression of a defensin-type gene family in bell pepper. Upregulation during ripening and upon wounding.
DRAMP00453	RTCESQSHRFKGLCFSKSNCGSVCHTEGFNGGHCRGFRRRCFCTRHC	47	Defensin J1-2 (Plant defensin)	O65740	Belongs to the DEFL family	Not found	Capsicum annuum (Bell pepper)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Tissue specificity: Expressed in flowers and in young fruits.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43."	"Fungi: Fusarium oxysporum, Botrytis cinerea."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8883377##9790581	Plant Physiol. 1996 Oct;112(2):615-622.##Mol Gen Genet. 1998 Sep;259(5):504-510.	"Meyer B, Houln? G, Pozueta-Romero J, Schantz ML, Schantz R.##Houln? G, Meyer B, Schantz R."	Fruit-specific expression of a defensin-type gene family in bell pepper. Upregulation during ripening and upon wounding.##Alteration of the expression of a plant defensin gene by exon shuffling in bell pepper (Capsicum annuum L.).
DRAMP00457	RTCESKSHRFKGPCVSTHNCANVCHNEGFGGGKCRGFRRRCYCTRHC	47	Defensin-like protein 1 (LCR68; Plant defensin 2.3; Plant defensin)	"Q9ZUL7, Q4VP02"	Belongs to the DEFL family	PDF2.3	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Bridge	Not found	None	"Tissue specificity: Expressed in the whole plant except roots.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637	Plant Biotechnol J. 2006 May;4(3):317-324.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.
DRAMP00458	RTCESQSHRFKGTCVSASNCANVCHNEGFVGGNCRGFRRRCFCTRHC	47	Defensin-like protein 2 (LCR69; Plant defensin 2.2; Plant defensin)	"Q39182, Q42011, Q4VP00, Q4VP03"	Belongs to the DEFL family	PDF2.2	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Bridge	Not found	None	"Function: Confers broad-spectrum resistance to pathogens.
Tissue specificity: Broadly expressed.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##8281187	Plant Mol Biol. 2001 May;46(1):17-34.##Plant J. 1993 Dec;4(6):1051-1061.##Plant Physiol. Biochem. 1998;36:533-537.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##H?fte H, Desprez T, Amselem J, Chiapello H, Rouz? P, Caboche M, Moisan A, Jourjon MF, Charpenteau JL, Berthomieu P, et al.##Thomma B.P.H.J, Broekaert W.F."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##An inventory of 1152 expressed sequence tags obtained by partial sequencing of cDNAs from Arabidopsis thaliana.##Tissue-specific expression of plant defensin genes PDF2.1 and PDF2.2 in Arabidopsis thaliana.
DRAMP00459	RICKSRSQKFKGPCVSEDNCANVCHTEGFPDGDCDGLLRRCYCNTHC	47	Defensin-like protein 3 (Protein LCR71; Plant defensin)	P82781	Belongs to the DEFL family	LCR71	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Bridge	Not found	None	PTM: Contains four disulfide bonds 3-47;14-34;20-41;24-43.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247	Plant Mol Biol. 2001 May;46(1):17-34.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
DRAMP00460	RTCASQSQRFKGKCVSDTNCENVCHNEGFPGGDCRGFRRRCFCTRNC	47	Defensin-like protein 4 (Protein LCR70; Plant defensin 2.1; Plant defensin)	"Q41914, Q541X5, Q9ZUL6"	Belongs to the DEFL family	PDF2.1	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Bridge	Not found	None	"Function: Confers broad-spectrum resistance to pathogens.
Tissue specificity: Expressed in roots, siliques and seeds.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##8281187	Plant Mol Biol. 2001 May;46(1):17-34.##Plant J. 1993 Dec;4(6):1051-1061.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##H?fte H, Desprez T, Amselem J, Chiapello H, Rouz? P, Caboche M, Moisan A, Jourjon MF, Charpenteau JL, Berthomieu P, et al."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##An inventory of 1152 expressed sequence tags obtained by partial sequencing of cDNAs from Arabidopsis thaliana.
DRAMP00461	RTCETSSNLFNGPCLSSSNCANVCHNEGFSDGDCRGFRRRCLCTRPC	47	Defensin-like protein 5 (Protein LCR66; Plant defensin 2.4; Plant defensin)	"Q9C947, A0MED6, Q1PFI2, Q8LEG6"	Belongs to the DEFL family	PDF2.4	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Bridge	Not found	None	"PTM: Contains four disulfide bonds 4-51; 15-36; 21-45; 25-47, and Pyrrolidone carboxylic acid at position 1."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637	Plant Biotechnol J. 2006 May;4(3):317-324.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.
DRAMP00462	RTCQSKSHHFKYMCTSNHNCAIVCRNEGFSGGRCHGFHRRCYCTRLC	47	Defensin-like protein 6 (Protein LCR74; Plant defensin 2.5; Plant defensin)	"Q9FFP8, P82783"	Belongs to the DEFL family	PDF2.5	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Bridge	Not found	None	PTM: Contains four disulfide bonds 4-47; 14-34; 20-41; 24-43.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247	Plant Mol Biol. 2001 May;46(1):17-34.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
DRAMP00463	QQMCEAKSLDWKGMCLKWRNCRQVCISEGFTDGRCKGFTRKCICSKPCFVLPN	53	Defensin-like protein 7 (Protein LCR75; LCR79; Plant defensin)	"P82784, P82788"	Belongs to the DEFL family	LCR75	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Bridge	Not found	None	"Tissue specificity: Expressed in stems, roots, rosette leaves and flower buds.
PTM: Contains four disulfide bonds 4-48;15-35;21-42;25-44."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247	Plant Mol Biol. 2001 May;46(1):17-34.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
DRAMP00465	QPQLCETKSLNYRGLCLKWRSCKRVCISEGFPDGRCKGFFNNKCVCRKPCALLSTEN	57	Defensin-like protein 9 (Protein LCR76; Plant defensin)	P82785	Belongs to the DEFL family	LCR76	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Bridge	Not found	None	PTM: Contains four disulfide bonds 5-50;16-36;22-44;26-46.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247	Plant Mol Biol. 2001 May;46(1):17-34.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
DRAMP00466	RTCESPSNKFQGVCLNSQSCAKACPSEGFSGGRCSSLRCYCSKAC	45	Defensin-like protein 10 (Protein LCR72; Plant defensin 2.6; Plant defensin)	"Q9ZUL8, Q0IGN8"	Belongs to the DEFL family	PDF2.6	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Bridge	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247	Plant Mol Biol. 2001 May;46(1):17-34.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
DRAMP00467	QKCEWECKLLPNFPCWLKGAGEGLCDNLCKYEGAISGVCVSDPHRCLCRNRKPGCS	56	Defensin-like protein 11 (Plant defensin)	"Q9M1V4, A0MF42"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Bridge	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637##15955924	Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00468	QMNDCDCDHDHRCGEWEDESHGNCKQHHLRVVCTCTLDCLDISSTSNA	48	Putative defensin-like protein 12 (Plant defensin)	Q2V477	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Bridge	Not found	None	"Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00469	QKLCERPSGTWSGVCGNSNACKNQCINLEKARHGSCNYVFPAHKCICYFPC	51	Defensin-like protein 13 (At-AFP1; Protein LCR67; Plant defensin)	"P30224, Q42179"	Belongs to the DEFL family	PDF1.1	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Protein level	Rich	Not found	None	"Function: Confers broad-spectrum resistance to pathogens. Possesses antifungal activity sensitive to inorganic cations in vitro.
Tissue specificity: Expressed predominantly in siliques and dry seeds.
PTM: Contains four disulfide bonds 4-51; 15-36; 21-45; 25-47, and pyrrolidone carboxylic acid at Q1."	"Fungi: Alternaria brassicola (IC50=10 ?g/ml), Botrytis cinerea (IC50=3.90 ?g/ml), Fusarium culmorum (IC50=3 ?g/ml), Fusarium oxysporum f.sp. lycopersici (IC50=3 ?g/ml), Pyricularia oryzae (IC50=0.25 ?g/ml), Verticiliium dahliae (IC50=1.50 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8422949##17180735##8989885	FEBS Lett. 1993 Feb 1;316(3):233-240.##Transgenic Res. 2007 Aug;16(4):531-538.##Plant Cell. 1996 Dec;8(12):2309-2323.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Sels J, Delaur? SL, Aerts AM, Proost P, Cammue BP, De Bolle MF.##Penninckx IA, Eggermont K, Terras FR, Thomma BP, De Samblanx GW, Buchala A, M?traux JP, Manners JM, Broekaert WF."	A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Use of a PTGS-MAR expression system for efficient in planta production of bioactive Arabidopsis thaliana plant defensins.##Pathogen-induced systemic activation of a plant defensin gene in Arabidopsis follows a salicylic acid-independent pathway.
DRAMP00470	QKLCEKPSGTWSGVCGNSNACKNQCINLEGAKHGSCNYVFPAHKCICYFPC	51	Defensin-like protein 14 (Plant defensin 1.3; Plant defensin)	O80995	Belongs to the DEFL family	PDF1.3	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"PTM: Contains four disulfide bonds 4-51;15-36;21-45;25-47, and Pyrrolidone carboxylic acid at position 1."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10617197	Nature. 1999 Dec 16;402(6763):761-768.	"Lin X, Kaul S, Rounsley S, Shea TP, Benito MI, Town CD, Fujii CY, Mason T, Bowman CL, Barnstead M, Feldblyum TV, Buell CR, Ketchum KA, Lee J, Ronning CM, Koo HL, Moffat KS, Cronin LA, Shen M, Pai G, Van Aken S, Umayam L, Tallon LJ, Gill JE, Adams MD, Carr"	Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.
DRAMP00474	LCKRESETWSGRCVNDYQCRDHCINNDRGNDGYCAGGYPWYRSCFCFFSC	50	Defensin-like protein 18 (Plant defensin 1.5; Plant defensin)	Q9FZ31	Belongs to the DEFL family	PDF1.5	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Confers broad-spectrum resistance to pathogens.
PTM: Contains four disulfide bonds 3-51; 14-35; 20-45; 24-47."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924##12447532	Plant Physiol. 2005 Jun;138(2):600-610.##Planta. 2002 Dec;216(2):193-202.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Thomma BP, Cammue BP, Thevissen K."	Genome organization of more than 300 defensin-like genes in Arabidopsis.##Plant defensins.
DRAMP00475	TEMMAVEGRICERRSKTWTGFCGNTRGCDSQCKRWERASHGACHAQFPGFACFCYFNC	58	Defensin-like protein 19 (Protein LCR78; Plant defensin 1.4; Plant defensin)	"P82787, Q8VZQ7, Q9FWR6"	Belongs to the DEFL family	PDF1.4	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Bridge	Not found	None	PTM: Contains four disulfide bonds 11-58;22-43;28-52;32-54.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247	Plant Mol Biol. 2001 May;46(1):17-34.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
DRAMP00476	QKHIAPWIFEDKSICCKEHPSVGRCLPGIDDDAEKDGKCWKFCIEGCETGGFCKLFEHKHICHCNCSG	68	Putative defensin-like protein 20 (Plant defensin)	Q2V2S1	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00477	QKHTAPWIPEDNSICCKEHPSVGRCLPNIDDSAEKGGKCWKFCIEGCETGGFCKLFGHKHICHCNCSG	68	Defensin-like protein 21 (Plant defensin)	"P0CAX9, O23285, Q2V3I6"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Bridge	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00478	YNVENGGSLCCNNHPKFGKCNTKNDDQRCNSWCLNGCDNGKGGYCKSMSHGGQCHCYC	58	Defensin-like protein 22 (Plant defensin)	Q2V391	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00479	SGSSLCCNTHAKFGACNTYQDRKRCNKWCLDGCDNKKGGFCKRFAGGAKKCHCYC	55	Putative defensin-like protein 23 (Plant defensin)	Q2V364	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00480	RKTVWPSSELDPKCCSNQPEFGICDSKEDDERCAQMCLDGCPTNKGGGCQPITEAPGAVCSCYCA	65	Defensin-like protein 24 (Plant defensin)	Q2V371	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00481	YNVESGGSLCCNNHPKFGKCNTNNDNQRCNRWCHNGCGNGKGDYCKAMSHGGLCHCYC	58	Putative defensin-like protein 25 (Plant defensin)	Q2V392	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00482	MIYNVESGGSLCCNSHPKFGKCNTNNDEQRCNRWCHNGCGNGKGGYYKSMSHGGQCHYYC	60	Putative defensin-like protein 26 (Plant defensin)	Q2V4J2	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	PTM: Problely contains two disulfide bonds.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00483	VMNEDSILSSNKGDSLCCNDHPEFGICTNKSCNKWCLQGCTRGGFCKRKICHCYC	55	Putative defensin-like protein 27 (Plant defensin)	Q2L6T3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00484	KENITPWIYSMKQPVSCNREHSEIGICLSGIDDDIQNDGKCWKFCLMVAKSGGYNADK	58	Putative defensin-like protein 28 (Plant defensin)	"P0CAY0, F4JUP3, O23285"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00485	KSMVEVNAAHKWYIVEGLCSKFPDCNKHCKEQKFPGGTCLKLGVNMMCTCIYS	53	Putative defensin-like protein 29 (Plant defensin)	Q2V3R9	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924##10907853	Plant Physiol. 2005 Jun;138(2):600-610.##DNA Res. 2000 Jun 30;7(3):217-221.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Kaneko T, Katoh T, Sato S, Nakamura A, Asamizu E, Tabata S."	"Genome organization of more than 300 defensin-like genes in Arabidopsis.##Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
DRAMP00486	KSMAKAQGGWYLVEGLCSKFPDCNKHCKEQGFLGGQCLKLGVNMLCFCIHT	51	Putative defensin-like protein 30 (Plant defensin)	Q2V3S0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Caution: Could be the product of a pseudogene. Lacks the signal peptide, which is a conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924##10907853	Plant Physiol. 2005 Jun;138(2):600-610.##DNA Res. 2000 Jun 30;7(3):217-221.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Kaneko T, Katoh T, Sato S, Nakamura A, Asamizu E, Tabata S."	"Genome organization of more than 300 defensin-like genes in Arabidopsis.##Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
DRAMP00487	EDRSKLIPIGPCSKIANCNQTCIESQFLGGKCIKWYPDSIKETCACLVKPSITHV	55	Putative defensin-like protein 31 (Plant defensin)	Q2V3D7	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00488	KDIDGRKPLLIGTCIEFPTEKCNKTCIESNFAGGKCVHIGQSLDFVCVCFPKYYI	55	Defensin-like protein 32 (Plant defensin)	Q2V4I8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00489	QNPRGRKCEDPNGVDQKAKCYIYCNEQGFLGGSCQGYTNHYMCECYVG	48	Putative defensin-like protein 33 (Plant defensin)	Q2V4D6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00490	QILTGIKCPDPNGHDKEDKCNIYCLNQNYMGGSCQGYKNHYMCECYVG	48	Defensin-like protein 34 (Plant defensin)	Q2V4D7	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00491	KSMNPTGRRCPDPNGVEKKSMCYSSCKTQGFMGGSCQGHKGNYMCECYEG	50	Defensin-like protein 35 (Plant defensin)	"Q2V4F3, Q9SH70"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00492	IESPIFTGNKCSDPTGMDKDGKCLDYCHAQGYPGGSCIGFIDQGYMCVCKVG	52	Putative defensin-like protein 36 (Plant defensin)	Q2V4D5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00493	TTAGRRDGKSGRTEWLYVAGECAKLPRCNKYCVSNGFHLGGFCEKLSPQASYLSCVCKYT	60	Defensin-like protein 37 (Plant defensin)	"Q56XC2, F4JSA4, Q9SVQ4"	Belongs to the DEFL family	EDA21	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00494	YCERVRSRSAPHDICKKKNGNAVCKEKCWTIEKYQNGRCLILPKTTKLDCYCYHFDQC	58	Putative defensin-like protein 38 (Plant defensin)	Q2V462	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00495	YCEKVRSKTAPRDVCKKSNGNALCKKTCWTIEKYVNGKCLILPKTTNLDCYCYHYDNGSACRA	63	Putative defensin-like protein 39 (Plant defensin)	Q2V460	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00496	LGTSPYCEKVLSRFAPPGNCLKKNGNALCKESCANEQFREGVCLHLPKPQSKLNCYCSVLKCP	63	Putative defensin-like protein 40 (Plant defensin)	Q2V325	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00497	MTQGKRKHPCDLKNPSKRAPPATCNKPNGAILCGDFCLHEGYNIGKCVMRRTGKACICSQCEGW	64	Defensin-like protein 41 (Plant defensin)	Q3E8B0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00498	MNWELCDDYPSKAPPETCNKVDGARRCRTSCNNEGYGGANCNLKGKVKVCECTILRVCLPHHKRPPHVPKPPK	73	Putative defensin-like protein 42 (Plant defensin)	P0CAY1	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"PTM: Contains four disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks the signal peptide, which is a conserved feature of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924##10907853	Plant Physiol. 2005 Jun;138(2):600-610.##DNA Res. 2000 Jun 30;7(3):217-221.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Kaneko T, Katoh T, Sato S, Nakamura A, Asamizu E, Tabata S."	"Genome organization of more than 300 defensin-like genes in Arabidopsis.##Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
DRAMP00499	SEIKPTGRIDDQCKQMCSATYGDGKCASDCRKAGFSSGRCLTSSPFGNKCCCTK	54	Defensin-like protein 43 (Plant defensin)	Q2V4J5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00500	SEIKPTGRVDNQCKEMCSATFGDGKCAADCRKAGFSSGRCLTSSPFGNKCCCT	53	Defensin-like protein 44 (Plant defensin)	Q9M833	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00501	SDIKPTGRIDNQCKRMCSATYGNGKCAADCRSDGFSSGQCFTSPPFDNRCCCNN	54	Defensin-like protein 45 (Plant defensin)	Q2V3Y8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00502	IDAGIKGFDTDHCDTRCYGRDECMNYCIKAGFPKGGQCGSLCIPCGFKCCCQK	53	Defensin-like protein 46 (Plant defensin)	"Q2V3V1, A0ME04"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00503	SDARIEGFSFDNCNIRCSEDYWNDECNKDCLRAGFQKGGQCGSPCIPCPVKCCCQK	56	Defensin-like protein 47 (Plant defensin)	Q3E7C7	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00504	AEIKKFSYDHCFHLCVAGEYGSNECFVDCAQKGFWHGDCANRTEKDPIRCCCYN	54	Putative defensin-like protein 48 (Plant defensin)	Q2V365	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00505	AETTKFSYDHCFHLCVEGEYGSRECFVDCTQKGFWHGVCANKTTAKDPIHCCCYN	55	Defensin-like protein 49 (Plant defensin)	Q2V366	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924##14993207	Plant Physiol. 2005 Jun;138(2):600-610.##Genome Res. 2004 Mar;14(3):406-413.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu?tier F, Scarpelli C, Sch?chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M."	Genome organization of more than 300 defensin-like genes in Arabidopsis.##Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation.
DRAMP00506	SEIKAKINGLECFNTCTPYYDDYKCNVDCLSSGYPAGDCHIVSPSQPKKCCCY	53	Defensin-like protein 50 (Protein LCR49; Plant defensin)	P82764	Belongs to the DEFL family	LCR49	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17229318##11437247##15955924	BMC Genomics. 2007 Jan 17;8:18.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Moskal WA Jr, Wu HC, Underwood BA, Wang W, Town CD, Xiao Y.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Experimental validation of novel genes predicted in the un-annotated regions of the Arabidopsis genome.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00507	SEIKAKINGLECFNTCTSYYDDHKCNVDCLSSGYPAGECYTVSPSQPKKCCCY	53	Defensin-like protein 51 (Protein LCR48; Plant defensin)	"P82763, A0MJW7, A7REH1"	Belongs to the DEFL family	LCR48	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17565583##11437247##15955924	Plant J. 2007 Jul;51(2):262-280.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00508	VSGPPKCIALCRPGYYERFECFHDCITEGYDDGSCVPGPTTAKCGIITKTTNKICYSFAFE	61	Putative defensin-like protein 52 (Plant defensin)	Q2V433	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"PTM: Problely contains two disulfide bonds.
Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00509	MFSQNICMWRDCFARCSPGYYERFECFHDCITKGYDDGNCVPGPKTGRCCCTR	53	Putative defensin-like protein 53 (Plant defensin)	P0CAY2	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"PTM: Contains four disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks the signal peptide, which is a conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00510	ESVIEPAKYGACLFLCDARRDDHACFYDCTNVAIYRTGHCVGNPPRCCCIRG	52	Defensin-like protein 54 (Plant defensin)	Q8GY39	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11910074##15955924##14993207	Science. 2002 Apr 5;296(5565):141-145.##Plant Physiol. 2005 Jun;138(2):600-610.##Genome Res. 2004 Mar;14(3):406-413.	"Seki M, Narusaka M, Kamiya A, Ishida J, Satou M, Sakurai T, Nakajima M, Enju A, Akiyama K, Oono Y, Muramatsu M, Hayashizaki Y, Kawai J, Carninci P, Itoh M, Ishii Y, Arakawa T, Shibata K, Shinagawa A, Shinozaki K.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu?tier F, Scarpelli C, Sch?chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M."	Functional annotation of a full-length Arabidopsis cDNA collection.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation.
DRAMP00511	LSNSDALASSVIETTKNDVCSTPCTIRYGTFECFQDCILDHFRDGNCINGRCCCKY	56	Putative defensin-like protein 55 (Plant defensin)	Q2V2Q4	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00512	DVLASSDIYICVTVIETTKNDVCSTPCTIRYGTFECFHDCILEHYRDGNCINGRCCCK	58	Putative defensin-like protein 56 (Plant defensin)	Q2V4A6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00513	SSVIETTKNDVCSTPCTRRYGTYECWHDCLHERYNDGGCVDGRCCCKK	48	Putative defensin-like protein 57 (Plant defensin)	Q2V4A8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00514	DVLVSSVIETSKNDVCFIPCTRRYGDWECYDDCLGKNFNDGGCVDGRCCCKK	52	Defensin-like protein 58 (Plant defensin)	"Q4VNZ9, F4IU82, F4IU83"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00515	LSNSDILVSSVIETSKYDVCFIPCTRRYEDRECNDDCLAKDFNDGGCVDGRCCCKY	56	Defensin-like protein 59 (Plant defensin)	Q4VNZ8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00516	EVLVAPVIETAQNDVCFVPCTSRYGHYECAFDCMHKRYKDGGCVHGRCCCKT	52	Putative defensin-like protein 60 (Plant defensin)	Q2V4A5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00517	YDRCIGPCLRFYGNHQCYKNCRKAKYDGGQCDFVKKGEKLPECCCYYNKN	50	Putative defensin-like protein 62 (Plant defensin)	Q2V485	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00518	SYNIGQTRLVVIQEQEPHCIGPCEIAFGNRPCNEECTSQQYAYGFCDYQTKGEDNPQCCCYTS	63	Putative defensin-like protein 63 (Plant defensin)	Q2V4G1	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00519	ERIDICFIPCTRRYGDYECWFDCTYNRYKEGGCVEDVVVKHNRNRPTFRAVELCFFSIKFMYDFSMK	67	Putative defensin-like protein 64 (Plant defensin)	Q2V4A7	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00520	FSVQIGISVQAAPPTCGRDCTEKFLTQDCDKYCVGLSYKKGVCILSEGLPPKTSTYRCCCS	61	Putative defensin-like protein 66 (Plant defensin)	Q2V2Y6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00521	VEMGISVQALPPTCGPDCTGRFMNQDCSKYCAALSYKHGVCILFRGLPPRTSTLRCCCG	59	Putative defensin-like protein 67 (Plant defensin)	Q3EBU2	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00522	YDLFSEIGISAATLVIPTCFENCNATFQDPECNKWCALLAYKDGSCLYPPSEVDDLPPIKRPYIPRCCCNPITLSPPSP	79	Defensin-like protein 68 (Plant defensin)	"Q2V4L5, A0MJT8, Q9LR89"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924##17147637##17229318	Plant Physiol. 2005 Jun;138(2):600-610.##Plant Biotechnol J. 2006 May;4(3):317-324.##BMC Genomics. 2007 Jan 17;8:18.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Moskal WA Jr, Wu HC, Underwood BA, Wang W, Town CD, Xiao Y."	Genome organization of more than 300 defensin-like genes in Arabidopsis.##Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Experimental validation of novel genes predicted in the un-annotated regions of the Arabidopsis genome.
DRAMP00523	YDLFTGIGIDARTVPPTCYESCNATFQNPECNKMCVGLAYKDGSCIYPPPEVDGLPPKRPYFPRCCCNPIILSPPSP	77	Defensin-like protein 69 (Plant defensin)	"Q9FL73, A0MFP1"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9679202##15955924##17147637	DNA Res. 1998 Apr 30;5(2):131-145.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant Biotechnol J. 2006 May;4(3):317-324.	"Kaneko T, Kotani H, Nakamura Y, Sato S, Asamizu E, Miyajima N, Tabata S.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P."	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations."
DRAMP00524	NFASGEASSQLCFNPCTPQLGNNECNTICMNKKYKEGSCVGFGIPPTSKYCCCKT	55	Putative defensin-like protein 70 (Protein LCR83; Plant defensin)	P82792	Belongs to the DEFL family	LCR83	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00525	LPSSVINGFGYDYCIVECSITFLDDACKPLCIDRGYSDGGCIGLSPHFKCCCKK	54	Defensin-like protein 71 (Plant defensin)	P82793	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00526	MKLSILVKAMKRNNGFRYDYCIAECSEHFLDDVCKPVCIDKGYSDGGCIGLAPNFKCCCKK	61	Putative defensin-like protein 72 (Plant defensin)	Q2V2S9	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"PTM: Contains four disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks the signal peptide, which is a conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00527	EPQCIGSCEMLADCNTACIRMGYLFGQCVGWKTPDMCCCNH	41	Putative defensin-like protein 73 (Protein LCR44; Plant defensin)	P82759	Belongs to the DEFL family	LCR44	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00528	QKECIGPCDMFTDCQAACVGIRKGYNYGQCVAWKPKDDDPFTCCCYKLTP	50	Defensin-like protein 74 (Protein LCR43; Plant defensin)	P82758	Belongs to the DEFL family	LCR43	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00529	ITVQADCIGPCNDDCQQLCKSKGYTDWTCASFRTKSSCCCKPPRHQIFEQNAQLNN	56	Defensin-like protein 75 (Protein LCR45; Plant defensin)	P82760	Belongs to the DEFL family	LCR45	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247	Plant Mol Biol. 2001 May;46(1):17-34.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
DRAMP00530	IDVHDAMCYRSECTSVCDQICLSHGYTNGWYCGTFRLHTGCCCLKKKELNQIISPSKN	58	Defensin-like protein 76 (Protein LCR86; Plant defensin)	P82795	Belongs to the DEFL family	LCR86	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10470850##11437247	DNA Res. 1999 Jun 30;6(3):183-195.##Plant Mol Biol. 2001 May;46(1):17-34.	"Kaneko T, Katoh T, Sato S, Nakamura Y, Asamizu E, Kotani H, Miyajima N, Tabata S.##Vanoosthuyse V, Miege C, Dumas C, Cock JM."	"Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence features of the regions of 1,011,550 bp covered by seventeen P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response."
DRAMP00531	RSNGIYDPMCPGVCGNLVKPDCNGLCHELGFPAGGYCKPGNTCCCKKKDSGPVDVPPTA	59	Defensin-like protein 78 (Plant defensin)	"Q9SL74, A0MJT1"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637##15955924##17565583	Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
DRAMP00532	YQMLICLDLNISCADCQKQCDETSYGGMCLNGGRTCCCKKSPPPSYYDPRPPSS	54	Putative defensin-like protein 79 (Plant defensin)	Q2V470	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00533	EVRDICPGVCHAGIEPDCDTLCISMGFTGGYCQGLTCCCNPKSSKSSIINRPI	53	Putative defensin-like protein 80 (Protein LCR81; Plant defensin)	P82790	Belongs to the DEFL family	LCR81	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00534	KSPVSCDGACTSTPQCNKICTSKGYKKGICHGSAHLFYICCCYAKFESQYDPSISSPPNY	60	Defensin-like protein 81 (Plant defensin)	Q2V4G6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637##15955924##17565583	Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
DRAMP00535	RTQEHPCQDYRLGCKSRDVCNAKCLSLGYVKGGDCVTFAFPICCCKINFGFQDDSPISSPIFTD	64	Defensin-like protein 82 (Plant defensin)	Q2V334	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14993207	Genome Res. 2004 Mar;14(3):406-413.	"Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu?tier F, Scarpelli C, Sch?chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M."	Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation.
DRAMP00536	QIITCLPGECTNPSECNAACKSNGYKGGACVSMSIGSTTGACCCKPNFKSQDSFKSNDIIINNN	64	Putative defensin-like protein 83 (Protein LCR46; Plant defensin)	P82761	Belongs to the DEFL family	LCR46	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10470850##11437247	DNA Res. 1999 Jun 30;6(3):183-195.##Plant Mol Biol. 2001 May;46(1):17-34	"Kaneko T, Katoh T, Sato S, Nakamura Y, Asamizu E, Kotani H, Miyajima N, Tabata S.##Vanoosthuyse V, Miege C, Dumas C, Cock JM."	"Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence features of the regions of 1,011,550 bp covered by seventeen P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response."
DRAMP00537	QSSKCTKGCTSTPECNIKCMKKGGGHCQAYIGRSHGRLAIENYCCCNNYSNSPISSPVMN	60	Putative defensin-like protein 84 (Plant defensin)	Q2V2Y3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00538	LISDKCTEGCKSTIGCNTRCMMRGGGYCESAKIHGAVKIFCCCNNYSNSPISSPVIN	57	Defensin-like protein 85 (Plant defensin)	Q8GXV6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11910074##9628582	Science. 2002 Apr 5;296(5565):141-145.##DNA Res. 1998 Feb 28;5(1):41-54.	"Seki M, Narusaka M, Kamiya A, Ishida J, Satou M, Sakurai T, Nakajima M, Enju A, Akiyama K, Oono Y, Muramatsu M, Hayashizaki Y, Kawai J, Carninci P, Itoh M, Ishii Y, Arakawa T, Shibata K, Shinagawa A, Shinozaki K.##Sato S, Kaneko T, Kotani H, Nakamura Y, Asamizu E, Miyajima N, Tabata S."	"Functional annotation of a full-length Arabidopsis cDNA collection.##Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence features of the regions of 1,456,315 bp covered by nineteen physically assigned P1 and TAC clones."
DRAMP00539	QFRGIKQCEMKCYSTPECNATCLHEGYEEGKCLKSWDGGVECCCLGLLASSHQDSSPISSPHYIIFHGICILNI	74	Putative defensin-like protein 86 (Protein LCR82; Plant defensin)	P82791	Belongs to the DEFL family	LCR82	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	PTM: Contains four disulfide bonds (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00540	QLKSTCRIAEAWKGAKECNAKCAALGTTRGGVCQKFLGDLYCCCWD	46	Defensin-like protein 87 (Plant defensin)	Q3E7S1	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Caution: Could be the product of a pseudogene. Lacks 1 of the 4 disulfide bonds, which are conserved features of the family.
PTM: Contains three disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00541	VEVIPCIAGSKCTNDMTYNELCRFKGFSKGGFCQKYVHQTIGRCCCHPTGLESQESSISGDTNVVITN	68	Putative defensin-like protein 88 (Plant defensin)	Q2V3J1	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00542	QTMQCYSGIACTDDGTCNDYCNPRNNNLGGVCLRRANCCCCYVSVVKSQESSLSKDTNNVFITN	64	Putative defensin-like protein 89 (Plant defensin)	Q2V3J0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00543	SPEKYYDCKQDGCITTPPCWRKCVSMGYPKGGECRIYSYGGVCCCDLTSKPPN	53	Defensin-like protein 90 (Plant defensin)	Q2V4G9	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00544	FTIAEPYIHPCMKGFCSFKSECANKCIFMGHHKGGDCIGGLDGIYCCCLA	50	Defensin-like protein 91 (Protein LCR47; Plant defensin)	P82762	Belongs to the DEFL family	LCR47	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14993207##11437247##15955924	Genome Res. 2004 Mar;14(3):406-413.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu?tier F, Scarpelli C, Sch?chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00545	WGKCDLRKGLCRLADTISTCDVPCRAVDSKYHGGECLNVGGGQGICWCCRDYDAAKSGAEKESM	64	Defensin-like protein 95 (Plant defensin)	"Q6NMS3, O49628"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00546	RQVCDYDKGECNSYEKSSTCIEPCKQLDSKFIGGRCIPVGGITGMGLCVCCRDVQRGAEKESM	63	Defensin-like protein 96 (Plant defensin)	"Q8L7G7, O49628, Q8H0Y6"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Confers broad-spectrum resistance to pathogens.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00547	RRVCDSAAGLCSMLFSCNTQCNSLGRNFTGGECSDARFPGLSVCYCCHNVESSAEMESM	59	Defensin-like protein 97 (Protein LCR85; Plant defensin)	"P82794, O49626, Q1PE59"	Belongs to the DEFL family	LCR85	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637##15955924##17565583	Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
DRAMP00548	RLVCDTPAGTCTSSSTCNDQCNTWGGNYSGGECADSSFPGLSICYCCHYVGSSAEMESM	59	Defensin-like protein 98 (Plant defensin)	"Q94AZ8, O49626"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00549	SCDFPLGACTPFRDCKESCIKFKTRAGQTFFDGKCRPRDRPSVWTACFCCYYDSIGAQ	58	Defensin-like protein 100 (Plant defensin)	"Q3E6U0, A0MJT5, O49626"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637##15955924##17565583	Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
DRAMP00550	FPASDQSIYARCIGPCPRYAVPHWCENECLSRKYMAGGECAFIEGEGPTPRCCCINL	57	Putative defensin-like protein 101 (Plant defensin)	Q2V337	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00551	RTTTGGSPGYGIGGRTKTCFTPALCIYRGVHGCDSYCKTKNFDYGYCRQEHCCCVNY	57	Putative defensin-like protein 102 (Plant defensin)	Q2V3L0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00552	LPTTARSPGYEIGPQRRRRVTCFSFSFCKPARGLASCDLFCKRLKFESGLCTGDLEKCCCIDYIN	65	Defensin-like protein 103 (Plant defensin)	Q8GXR4	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11910074##15955924	Science. 2002 Apr 5;296(5565):141-145.##Plant Physiol. 2005 Jun;138(2):600-610.	"Seki M, Narusaka M, Kamiya A, Ishida J, Satou M, Sakurai T, Nakajima M, Enju A, Akiyama K, Oono Y, Muramatsu M, Hayashizaki Y, Kawai J, Carninci P, Itoh M, Ishii Y, Arakawa T, Shibata K, Shinagawa A, Shinozaki K.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Functional annotation of a full-length Arabidopsis cDNA collection.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00553	LPMTHGGKPGYGIERTIIRPEWRCYVDEGCPKGQGAPCEKNCKNVADYGICIGIKCCCFDVIPVPPT	67	Putative defensin-like protein 104 (Plant defensin)	Q2V476	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00554	MLMACYSAGQLGCLVFCNEAEYSYGKCIGRGRCCCYDL	38	Putative defensin-like protein 105 (Plant defensin)	P0CAY3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00555	HTTIASAPSSGEPTTYATGPALSKHSHDNDGICFVTPACFAPGQYEIGCIVYCHESHYKHYKCVNRSCCCYNTDKNASELK	81	Defensin-like protein 106 (Plant defensin)	"Q1G3Y1, A0MDJ9, Q9SYA4"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637##15955924##17565583	Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
DRAMP00556	RMTTTTSPGFGIKQQDRQCFEHAPYLCRGGEGDCRMYCRDLDFSFGTCFSGVCCCQI	57	Defensin-like protein 107 (Plant defensin)	Q2V413	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00557	RMTTASTPGYGIKQEDRLCIQGQEGTKLCSSGTSRDCLNFCLIRGYAGGSCYAYTLDQCCCRIPPPKLK	69	Defensin-like protein 108 (Protein LCR51; Plant defensin)	"A8MQN0, O80684"	Belongs to the DEFL family	LCR51	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00558	RPSFKPIPLFGEKLTQCFDTRPCLQGMLKCIEFCSSMGTADGQCNNENLCCCTHE	55	Defensin-like protein 109 (Plant defensin)	Q2V390	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9679202##15955924	DNA Res. 1998 Apr 30;5(2):131-145.##Plant Physiol. 2005 Jun;138(2):600-610.	"Kaneko T, Kotani H, Nakamura Y, Sato S, Asamizu E, Miyajima N, Tabata S.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Genome organization of more than 300 defensin-like genes in Arabidopsis."
DRAMP00559	RSTSDIVSGSGIKEDEHVCFKTSPCLPEVGGEKGCIAFCSRMKFTTGLCLGSVVCCCYT	59	Putative defensin-like protein 110 (Plant defensin)	Q2V4N0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00560	SDDTQGFGIKQEYKQCYTPDPCRKGGNDECERFCVAKSGLLYGKCINDGSKDVCCCLTK	59	Putative defensin-like protein 111 (Protein LCR50; Plant defensin)	P82765	Belongs to the DEFL family	LCR50	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00561	SDRTSGVGINQEYAKCYDLADCQKPKVDDAACERFCGAKSFLLYGKCDTATNKCCCKSKTK	61	Defensin-like protein 112 (Plant defensin)	Q2V488	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00562	SDSFPGLGLKKQAHKQCYSPDLCTGGDSKCDICCVLISGVYYGKCIQSKCHCLNKTK	57	Defensin-like protein 113 (Plant defensin)	Q2V342	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00563	SELDNTSGFEIKQEDKCYGPEPCKNGYEGCLFFCVRIAYYLYGECTMKPDHQKHCCCVTK	60	Putative defensin-like protein 114 (Plant defensin)	Q2V322	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00564	SDSTLGIGINQDWKKCFSPDPCKKAGTQGCMEFCRTISFLLFGECTSKPDQCCCVTK	57	Defensin-like protein 115 (Plant defensin)	Q2V321	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00565	SDSALGIGIKEDWEVCFSIDPCLTGEGTLGCTKWCRNHINLSLVGYCRTDPEHCCCVAEK	60	Defensin-like protein 116 (Plant defensin)	Q3E8I8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9679202##15955924##14993207	DNA Res. 1998 Apr 30;5(2):131-145.##Plant Physiol. 2005 Jun;138(2):600-610.##Genome Res. 2004 Mar;14(3):406-413.	"Kaneko T, Kotani H, Nakamura Y, Sato S, Asamizu E, Miyajima N, Tabata S.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu?tier F, Scarpelli C, Sch?chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M."	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation."
DRAMP00566	SDGTSGYGITEATKRCFTPAPCTRGLFYCQTFCSSLSAVLIGVCESGICCCILNQ	55	Defensin-like protein 117 (Plant defensin)	Q2V4G3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637##15955924##17565583	Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
DRAMP00567	QEMCRDILMKAKNCDEGTCDTLCKQKWKGNGSCFPNVYTYRKSCLCTFPCKT	52	Putative defensin-like protein 118 (Protein LCR52; Plant defensin)	P82766	Belongs to the DEFL family	LCR52	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00568	QEMCRDLLMRAKNCDDSTCATLCKQKWKGNGSCFPNVYRKSCLCTFPCKT	50	Putative defensin-like protein 119 (Protein LCR53; Plant defensin)	P82767	Belongs to the DEFL family	LCR53	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00569	QEMCHDLIKKTDCDDATCVTLCKQKWNGNGGGSCFQIVNLKSCLCAFPCQV	51	Putative defensin-like protein 120 (Protein LCR56; Plant defensin)	P82770	Belongs to the DEFL family	LCR56	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00570	QETCHDLIMKRDCDEATCVNMCQQKWKGSGGSCFQNFNVMSCICNFPCQV	50	Putative defensin-like protein 121 (Protein LCR55; Plant defensin)	P82769	Belongs to the DEFL family	LCR55	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00571	QELCHDYMSGTELCEEDKCVAKCIWMHGTAAKGTCMPKPSKQCVCTYSCNA	51	Defensin-like protein 122 (Protein LCR30; Plant defensin)	P82745	Belongs to the DEFL family	LCR30	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
Tissue specificity: Expressed in flower buds, but not in stems, roots or rosette leaves.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00572	MRPRSRAGDKFMSQGQELCHEYFQLTAPCEKQPCIDMCSSKYKTGKGVCGPAVHQCFCTFSCTV	64	Defensin-like protein 123 (Plant defensin; Uncertain)	Q0WN71	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924##17565583	Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
DRAMP00573	ANCVNYFEITFPEVCEANWCAAECLKAYKNGKGTCWQKFCQCVYDC	46	Defensin-like protein 124 (Protein LCR16; Plant defensin)	"P82731, A0MJV4"	Belongs to the DEFL family	LCR16	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637##15955924##17565583	Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
DRAMP00574	EEKQCYDYLLTPQENCEGLICAHECTMQHGGNGVCVDTTSTVCICTYDCTS	51	Defensin-like protein 125 (Protein LCR54; Plant defensin)	P82768	Belongs to the DEFL family	LCR54	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00575	QHAMCHEILPETDCGAGSCTALCLQLWRGTGKCVRTNDQKLICLCNFECIV	51	Putative defensin-like protein 126 (Protein LCR6; Plant defensin)	P82721	Belongs to the DEFL family	LCR6	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9679202##11437247##15955924	DNA Res. 1998 Apr 30;5(2):131-145.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis."
DRAMP00576	QNAICQKFLSETDCGAGSCTALCLQLWKGIGKCIKTDDHKLLCLCKYECIV	51	Defensin-like protein 127 (Protein LCR20; Plant defensin)	"P82734, Q4VP05, Q4VP06"	Belongs to the DEFL family	LCR20	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9679202##11437247##15955924	DNA Res. 1998 Apr 30;5(2):131-145.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis."
DRAMP00577	QHICHQILLNNNCDGATCTSLCDKQLQGTGQCYKTVDKRFICLCNYLCRT	50	Putative defensin-like protein 128 (Protein LCR8; Plant defensin)	P82723	Belongs to the DEFL family	LCR8	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00578	DTCHEYLYPEKCENNQCNSECATKFKEVGVFGFCVPPRSEPTEQFCICSYNC	52	Putative defensin-like protein 129 (Protein LCR13; Plant defensin)	P82728	Belongs to the DEFL family	LCR13	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00579	SIFIKYSDRTCHVYIKAENCEIDQCNWECGTKYKRVGVQGLCVPPGFDPIDQACLCSFNC	60	Defensin-like protein 130 (Protein LCR28; Plant defensin)	"P82743, Q2V320"	Belongs to the DEFL family	LCR28	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9679202##11437247##15955924	DNA Res. 1998 Apr 30;5(2):131-145.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis."
DRAMP00580	HICHDYLEGDHCDPKDCNLDCRDKWKGTGTCEPPTGTPLTRTCYCTYDC	49	Putative defensin-like protein 131 (Protein LCR29; Plant defensin)	P82744	Belongs to the DEFL family	LCR29	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00581	NDEQLRGNRCFQIKFKTGKCVPKECQTACQEKLRKPKLKGEGFCMKECTCCFYT	54	Putative defensin-like protein 133 (Protein LCR33; Plant defensin)	P82748	Belongs to the DEFL family	LCR33	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00582	FSPEDCLDDVGWILICTKPTCKFSCWTSRSVNKGRKMQDYWCSDSNTCHCVFCTGD	56	Putative defensin-like protein 134 (Plant defensin)	P0CAY4	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00583	QRRKCDEKIVLQFCNGRNRCYEYCDTKECVAACKKKRNGEGICNGDVFSVSAQCLCLYKC	60	Putative defensin-like protein 135 (Plant defensin)	Q2V3K1	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00584	NMSVDQKRCWATLKENNCVHDECRSMCLKKNPKGHGRCIKSSKGRIICLCGYDCP	55	Putative defensin-like protein 137 (Protein LCR14; Plant defensin)	P82729	Belongs to the DEFL family	LCR14	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00585	QPLGTMERCYDMLTWGECVPDNCAFSCALKRHGKGGCIKAYDNRPACVCYYTCLRS	56	Putative defensin-like protein 139 (Protein LCR7; Plant defensin)	P82722	Belongs to the DEFL family	LCR7	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00586	QPLEEMVECKEVLWPEECKYDACAFACALKRHGKGGCLEGPDYRSACICQYACKRS	56	Defensin-like protein 140 (Protein LCR15; Plant defensin)	P82730	Belongs to the DEFL family	LCR15	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00587	QQQQQRCEEALTEIDCGAGNCNALCLQKRKGLGRCVQRTPCDKLKCMCYYPCSS	54	Defensin-like protein 141 (Protein LCR3; Plant defensin)	P82718	Belongs to the DEFL family	LCR3	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9679202##11437247##15955924	DNA Res. 1998 Apr 30;5(2):131-145.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis."
DRAMP00588	EKLTTCSRFLSQKSGKCVKEDCDRMCKQKWPGKYTVGHCYGQFKDAKRCLCSVCGPDRQPP	61	Putative defensin-like protein 142 (Protein LCR34; Plant defensin)	P82749	Belongs to the DEFL family	LCR34	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00589	MVNGQCSFPQPVGPNGKCVPKDCKSLCHKKYKGGSICTTGKPNICMCLVCRRRSPEV	57	Defensin-like protein 144 (Protein LCR10; Plant defensin)	"Q8S8H9, A0MJT0, P82725, Q1PF66"	Belongs to the DEFL family	LCR10	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147637##15955924##17565583##11437247	Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.##Plant Mol Biol. 2001 May;46(1):17-34.	"Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA.##Vanoosthuyse V, Miege C, Dumas C, Cock JM."	Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
DRAMP00590	NLQQRRQMNQTWCSRPLLTHKQTGKCVIEDCESKCRQKWKGNGTQATCRNQCNCHFRCPWIQGQP	65	Putative defensin-like protein 145 (Protein LCR2; Plant defensin)	P82717	Belongs to the DEFL family	LCR2	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00591	NVQQVKREQCHTVIPNKSGKCIFTECKSACEKLKKPVASLCLPPKTCRCYHFCS	54	Putative defensin-like protein 146 (Protein LCR9; Plant defensin)	P82724	Belongs to the DEFL family	LCR9	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00592	NVQQKRSNRCIDFPVNPKTGLCVLKDCESVCKKTSKGLEGICWKFNAKGKDPKQCKCCGLWPPLY	65	Defensin-like protein 147 (Protein LCR1; Plant defensin)	P82716	Belongs to the DEFL family	LCR1	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00593	NVEQKSQDWCWSIVNKDRCLQKECESLCSKKHPKGKFMCIPSTPGGPFQCHCRHPCR	57	Putative defensin-like protein 148 (Protein LCR4; Plant defensin)	P82719	Belongs to the DEFL family	LCR4	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00594	NEGLGKPKKQCNEILKQSNCVAAECDSMCVKKRGKGAGYCSPSKKCYCYYHCP	53	Defensin-like protein 149 (Protein LCR5; Plant defensin)	"Q8S8H3, P82720, Q8LGD4"	Belongs to the DEFL family	LCR5	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00595	DVDQGYKQQCYKTIDVNLCVTGECKKMCVRRFKQAAGMCIKSVPSAPAPNRCRCIYHC	58	Putative defensin-like protein 150 (Protein LCR32; Plant defensin)	P82747	Belongs to the DEFL family	LCR32	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00596	QAPSTCFEALKDASKGASCDSELCASLCKKKSGGGVGTCRTKTTQPSKGQPECHCRFWCKSDGTPYK	67	Defensin-like protein 151 (Protein LCR17; Plant defensin)	"Q9T0E3, Q6GKX9"	Belongs to the DEFL family	LCR17	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00597	KQRLCIKVLTNASHVSKGASTCDSKLCTSLCEKISPQGVSFCKPIATTGQSKKGNPVCNCRYWCRSDGTPHTT	73	Putative defensin-like protein 152 (Protein LCR11; Plant defensin)	P82726	Belongs to the DEFL family	LCR11	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00598	KVPCLSRMFNKNNTCSFLRCEANCARKYKGYGDCRPGDRPHDKKDSLFCFCNYPC	55	Defensin-like protein 153 (Protein LCR31; Plant defensin)	"P82746, A0MJV0"	Belongs to the DEFL family	LCR31	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00599	VVEKAKGDGSCTIIIDPKAPSCDIIQCRLSCITDYNGLAECIASRIGSPPNCVCTYDC	58	Putative defensin-like protein 154 (Protein LCR35; Plant defensin)	P82750	Belongs to the DEFL family	LCR35	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00600	DKRCSIIIDLSPCYPIECRLSCITERNGDGECVVSKVGSTPNCLCTYDC	49	Defensin-like protein 155 (Protein LCR36; Plant defensin)	P82751	Belongs to the DEFL family	LCR36	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00601	KRHCSTIILPESPCVPQDCVEYCFEEYNGGGTCIASKTGRTTNCMCTYNCHGNNL	55	Defensin-like protein 156 (Protein LCR21; Plant defensin)	P82735	Belongs to the DEFL family	LCR21	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00602	DERCTIIIHPGSPCDPSDCVQYCYAEYNGVGKCIASKPGRSANCMCTYNC	50	Putative defensin-like protein 157 (Protein LCR22; Plant defensin)	Q9M0F3	Belongs to the DEFL family	LCR22	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00603	DQTDKYCTIIIDPRTPCDLVDCRLSCYTGYNGVGKCIASKASRTPNCVCTYNC	53	Putative defensin-like protein 158 (Protein LCR23; Plant defensin)	P82737	Belongs to the DEFL family	LCR23	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00604	KRCHLTIDKATACSLSDCRLSCYSGYNGVGKCFDDPKVAGPSNCGCIYNC	50	Defensin-like protein 159 (Protein LCR25; Plant defensin)	"P82739, A0MJW9"	Belongs to the DEFL family	LCR25	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00605	DEGKRCHTTIDKGNFCDLVDCRLSCFSGYNGVGKCFDDPKVPGRSNCGCLYNC	53	Putative defensin-like protein 160 (Protein LCR26; Plant defensin)	Q9M0F2	Belongs to the DEFL family	LCR26	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00606	EECRLTIDKATPCHLSDCRLSCYTGYNGVGECFDDPNVPGPDNCGCRYNC	50	Defensin-like protein 161 (Protein LCR27; Plant defensin)	Q9M0F1	Belongs to the DEFL family	LCR27	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00607	GATIKKCVVDVKLSKPCTFQECQPLCLQKYNGNGLCPGDDNNICACVYNC	50	Putative defensin-like protein 162 (Protein LCR37; Plant defensin)	P82752	Belongs to the DEFL family	LCR37	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00608	ADIKRCVVDVKLSKPCTFQECIPLCFQRYNGNGVCTGKKNEICTCAYNC	49	Defensin-like protein 163 (Protein LCR24; Plant defensin)	"Q8LFM0, P82738, Q0V821"	Belongs to the DEFL family	LCR24	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00609	KQLKTCTSVIKLGHPCDIESCLNECFRVYNTGFATCRGDKYSQLCTCEYNC	51	Defensin-like protein 164 (Protein LCR38; Plant defensin)	P82753	Belongs to the DEFL family	LCR38	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00610	QKRCRQELEPGKQCVLAKCRELCFKQLKGFGSCIEKPPGSSKYTCNCFYNCGPPGFF	57	Putative defensin-like protein 165 (Protein LCR12; Plant defensin)	P82727	Belongs to the DEFL family	LCR12	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00611	LYMCVSSTCVIQWCAIQCKRKEANGIGTCKPRPNQGKIQYRKLKEECHCVYKCS	54	Defensin-like protein 166 (Plant defensin)	P0CAY5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00612	RNRICRTSEKYYREFCGHAGNDDCLSKSTKKPKPFKCVCHDNRSQNITSINDRYNNCICTFYC	63	Putative defensin-like protein 168 (Plant defensin)	Q2V3Q1	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00613	LMDSMPQRHPVEGWCKRPLPNQKPGPCNNDRCSARCKEQKQFEFKGGKAMGICSSENRCLCTFRCR	66	Putative defensin-like protein 169 (Plant defensin)	Q2V3K0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00614	NMGCMAVLGSCGVITDCSGSCKTKFGQDASGDCDRDGGQGTCMCGYPCPHDKLHM	55	Putative defensin-like protein 170 (Protein LCR62; Plant defensin)	P82776	Belongs to the DEFL family	LCR62	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00615	NMGCMAVLGSCGVITDCSGECISRFGPQARGYCDRDGGSGTCVCVYPCPADKPHM	55	Defensin-like protein 171 (Protein LCR61; Plant defensin)	"P82775, Q4VNZ4"	Belongs to the DEFL family	 LCR61 	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00616	NMGCTATMGPCEKDKSCSATCRATFGDRANGFCDYSTSTSPGGECTCVYHCPPVVPHESHL	61	Defensin-like protein 172 (Protein LCR60; Plant defensin)	P82774	Belongs to the DEFL family	LCR60	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00617	NMGCIQIIGRCIKIPDCSASCRKFLGPHASGYCDNDGAGGTCICTYPCQTKEIHM	55	Defensin-like protein 173 (Protein LCR63; Plant defensin)	"P82777, Q4VNZ3"	Belongs to the DEFL family	LCR63	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00618	NTGCFDYDVYQPCDHCRERCLKYYPVTRKAICRKNHCVCIGPCPNDKAIPNVKLFKNVKEQILS	64	Defensin-like protein 175 (Plant defensin)	Q2V4H7	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00619	NTGCFDYDVYQPCDHCRERCLKYYPVTRKAICRKNHCVCIGPCPDDKAIPDVKLFKNVKEQILS	64	Defensin-like protein 176 (Protein LCR65; Plant defensin)	"P82779, A0MJW1"	Belongs to the DEFL family	LCR65	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00620	NMGCNDYIVGDVCVHCRERCLRYYPVTRKAECYRNHCLCIGPCPDDRPHKRFQMLNSSKNVKAQILS	67	Defensin-like protein 178 (Protein LCR64; Plant defensin)	"P82778, A0MJW0"	Belongs to the DEFL family	LCR64	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00621	QTCDENLSSCENCDQRCKAKHGPSSVSKCNGPDGTCGCASFKPAKLCIGATDMCTDKCPTSCCDRQCAIKYKNGKGGCVDYAGYRMCICEYTC	93	Putative defensin-like protein 179 (Protein LCR57; Plant defensin)	P82771	Belongs to the DEFL family	LCR57	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains seven disulfide bonds (By similarity).
Caution: Contains 7 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00622	SICNDRLGLCDGCDQRCKAKHGPSCESKCDGPVGMLLCTCTYECGPTKLCNGGLGNCGESCNEQCCDRNCAQRYNGGHGYCNTLDDFSLCLCKYPC	96	Defensin-like protein 181 (Protein LCR80; Plant defensin 3.1; Plant defensin)	"P82789, A0MJT6, Q1PDQ7"	Belongs to the DEFL family	PDF3.1	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Confers broad-spectrum resistance to pathogens. 
PTM: Contains eight disulfide bonds (By similarity).
Caution: Contains 8 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00623	NTCIEGIGNCQQCDVRCKARHGPAAKGACDSKFQLCTCNYPCGQGPSPPQPKKCYGGAGICSDRCGAQCCNQNCAQKYNQGSGFCDSIGNTSLCKCQYNC	100	Defensin-like protein 183 (Protein LCR19; Plant defensin)	"P82733, Q4VNZ2"	Belongs to the DEFL family	LCR19	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains eight disulfide bonds (By similarity).
Caution: Contains 8 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00624	NKKMVGEAKKCDQTWTCEGEDKCREKCLTLHNGVGVCDLYTAPLVPKQCFCHYDC	55	Putative defensin-like protein 184 (Protein LCR18; Plant defensin)	P82732	Belongs to the DEFL family	LCR18	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00625	KTCSDGWTCLGPKEEDKCKENCMAKHKGVGTCNLYTIPEFPAPITYYMCDCMFDC	55	Putative defensin-like protein 185 (Protein LCR39; Plant defensin)	P82754	Belongs to the DEFL family	LCR39	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00626	KTCSDGWTCVGEDKCKVNCMAKHKGVGTCTLYIIPSFPAPITSYICDCMFDC	52	Putative defensin-like protein 186 (Protein LCR40; Plant defensin)	P82755	Belongs to the DEFL family	LCR40	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00627	ENQKMVGEAKQCKTGWACFGEDACKEKCMAKYKGVGTVTYFPFPPETIIIYCECLYDC	58	Putative defensin-like protein 187 (Protein LCR42; Plant defensin)	P82757	Belongs to the DEFL family	LCR42	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00628	ENGIMIGEAKKCSNSWICEGDEKCKEKCMADYKGNGTCYYPSPPSKQHPEFFYPTCWCGFDC	62	Putative defensin-like protein 188 (Protein LCR41; Plant defensin)	P82756	Belongs to the DEFL family	LCR41	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00629	MSNGMPRTVPCIEGRILWNRTLPCSSILCGDHCVPHGYRAGTCDIVNDRAICKCSRCR	58	Putative defensin-like protein 189 (Plant defensin)	Q2V468	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00630	MRMTQKVSCIEGRTLWARPPKFFYCSSTLCEDNCINTGAYRGGTCDMEDEVAICRCHRCKKII	63	Putative defensin-like protein 190 (Plant defensin)	Q2V467	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00631	KKPPCLEGRTAYVSPGPCSNSLCTQDCRPAGYHTGKCKVEWSTPICKCYGCRKV	54	Putative defensin-like protein 191 (Plant defensin)	Q2V466	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00632	YDRKCLKEYGGDVGFSYCAPRIFPTFCDQNCRKNKGAKGGVCRWEENNAIGVKCLCNFCSEEPSDQTLSRI	71	Defensin-like protein 192 (Trypsin inhibitor ATTI-7; Plant defensin)	"Q42330, Q9SX84"	Belongs to the DEFL family	O22866	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00633	QGSKCLKEYGGNVGFSYCAPRIFPSFCYRNCRKNKGAKGGRCRSGGAGAGSMICLCDYCSDKP	63	Defensin-like protein 193 (Trypsin inhibitor ATTI-2; Plant defensin)	"O22866, Q67YC6, Q6ZZT9"	Belongs to the DEFL family	ATTI2	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00634	KDKECLKGYIDAPLSYCMARIYPSLCYRNCRFYKGAKGGKCDGLKCFCDFCSDKPF	56	Defensin-like protein 194 (Trypsin inhibitor ATTI-3; Plant defensin)	"O22867, B9DGH7, F4IR67, Q6ZZP9, Q6ZZQ4, Q6ZZQ9, Q6ZZR4, Q6ZZR9, Q6ZZT8"	Belongs to the DEFL family	ATTI3	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00635	QGNECLKEYGGDVGFGFCAPRIFPTICYTRCRENKGAKGGRCRWGQGSNVKCLCDFCDDTPQ	62	Defensin-like protein 195 (Trypsin inhibitor ATTI-1; diDi 4T-1; Plant defensin)	"Q42328, O22865, Q6ZZP6"	Belongs to the DEFL family	ATTI1	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	"The protein contains one alpha-helix and two strands of antiparallel beta-sheet, with a type IV beta-turn connecting the two strands. The alpha-helix and the inhibitory loop are connected to the beta-sheet through three disulfide bridges; a fourth disulfide bridge connects the N- and C-termini. (Ref.3)"	1JXC resolved by NMR.	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924##12369816	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.##Biochemistry. 2002 Oct 15;41(41):12284-96.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Zhao Q, Chae YK, Markley JL."	"Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##NMR solution structure of ATTp, an Arabidopsis thaliana trypsin inhibitor."
DRAMP00636	HDSECLKEYGGDVGFGFCAPKIFPTICYRNCQKDKGANGGKCLWGEGGKVKCLCDFCSNESFNQFISLT	69	Defensin-like protein 196 (Trypsin inhibitor ATTI-4; Plant defensin)	"Q8RYE7, Q6ZZS3"	Belongs to the DEFL family	ATTI4	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00637	KDDKFICVVEYGGDVGPTFCNPKFFPTLCRQNCRSFKGAKGGKCVKQPKHKHIKCFCDYCKDD	63	Defensin-like protein 197 (Trypsin inhibitor ATTI-6; Plant defensin)	"O22869, F4IR70, Q6ZZS7, Q6ZZU1, Q8GWN0"	Belongs to the DEFL family	ATTI6	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity).
Caution: Was initially thought (PubMed:15082560) to be a protease inhibitor."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00638	RTTTSGYGMLFDSVACEGGFEYCPRGGGNDKCTTFCRSLPNKYDFGVCDKIYACCCHINV	60	Defensin-like protein 199 (Plant defensin)	Q2V4G5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00639	RETRMMEQTCPVFWPMVPCDANKCEQMCRDYYGSVPSYCNRIGTPIAECACSLTPC	56	Defensin-like protein 201 (Plant defensin)	Q2V4N2	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00640	KTCKLFRGECPVDPCEPEKCDECCKATFGKQICGKCEQESTELHCHCRR	49	Putative defensin-like protein 202 (Plant defensin)	Q2V3J6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00641	QTCFKGEAQEGVCVKVDGSKLCDLLCRATNTTWFGACEVEDNETHCHCYGPC	52	Putative defensin-like protein 203 (Plant defensin)	Q2V424	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00642	HCDHFLGEAPVYPCKEKACKSVCKEHYHHACKGECEYHGREVHCHCYGDYH	51	Defensin-like protein 204 (Plant defensin)	Q56XB0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00643	NCDTYLGEVTVYYPCRERDCEAQCYEHYPHSCKGECEHHDHVVHHDNEEEHCHCYGR	57	Defensin-like protein 205 (His-rich; Plant defensin)	Q9M9M3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00644	ACFTFLGECGPEPFTGSNADCLACCVALYKSPPVCAGRVEGVPAHCHCYKS	51	Defensin-like protein 206 (Plant defensin)	"Q94JR6, Q9M1Y2"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00646	ACFKFLGECGAVPFPGTNADCTSCCVGNFGSAVCAGRVEVEGGVKHCHCYGTS	53	Defensin-like protein 208 (Plant defensin)	Q2V2Q8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00647	IITKTMNSKETIYLDNPAVSPSIDQNLVDIHLGHSFVQGVMSFCYDCGKACFRRGKNLARCQKFVCRCTISKLR	74	Defensin-like protein 209 (Plant defensin)	Q2V3K2	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00648	IITKTMNSKETTYLDSPAVSPSIDQYLVDIHLGHSFLQGVMSFCYDCGKACFRRGKNLARCKKFVCRCTKSGIK	74	Defensin-like protein 210 (Plant defensin)	Q2V3K4	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00649	IVMKSSNSKERTYPVTPALNPLTGQHSLRQRQLIFCDECANACFRRKKPVRSCQRFICRCAIRDVGY	67	Putative defensin-like protein 211 (Plant defensin)	Q2V3K7	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00650	VLINGSSDEERTYSFSPRASPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRYSISDIK	71	Defensin-like protein 212 (Plant defensin)	A8MRC6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains two disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00651	TLINGSSDEERTYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISDIK	71	Defensin-like protein 213 (Plant defensin)	"Q4VP08, Q9LSW1"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00652	ILINESSDEERTYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISGIK	71	Defensin-like protein 214 (Plant defensin)	Q4VP10	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00653	ILINESSDEQRIYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISGIK	71	Defensin-like protein 215 (Plant defensin)	Q4VP07	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00654	ILINESSDEQRIYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISDIK	71	Defensin-like protein 216 (Plant defensin)	P0CAY6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00655	ILIKESSEEERIYPFNPVASPFDPRSLNQILKIGKIGYCFDCARACMRRDRYIRTCSFERKLCRCSYSHIHHTHG	75	Defensin-like protein 217 (Plant defensin)	Q4VP09	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00656	KNKKVVIIPGPKGERPDIKVVEGPSTVEDDFCYDCVRRCMVKGVGFYFRSCKGFVCRCYYPFMGGYGP	68	Defensin-like protein 218 (Plant defensin)	Q2V370	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00657	FFKKLFLRASNIMIKSISEGKSQFSGPALSPNIDPADEHIGHSPEDMKIIFCQQCAFHCIEKKKNIAHCENSICRCTLEDIL	82	Defensin-like protein 219 (Plant defensin)	Q2V305	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00658	NIMTKSISQVKSQFFSPALSPNVDPADEHIGHSPDDMKIIFCQQCAFHCIEKKKNIGNCENSICRCTLEDIL	72	Defensin-like protein 220 (Plant defensin)	Q2V304	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00659	NIMTKSILEGKTQFSIPSLSSTIDPAYEHIGHFPDDMKIIFCQQCAFHCIEKKKNIPHCENSICRCTLENIL	72	Putative defensin-like protein 221 (Plant defensin)	Q2V306	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00660	TVKSYSEEKTHSFDLTANPPIDLNIVDELPRDEHLGVSHADNVIGFCQECAHHCLQRKRVLGECRWFTCHCSRITIGVGL	80	Defensin-like protein 222 (Plant defensin)	Q2V300	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00661	VVPSSFKRVEGPVTAASADFCYKCSRGCYRRYRRPVFCQGSICRCSSFIDDGY	53	Defensin-like protein 223 (Plant defensin)	Q2V369	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00662	MKKFGCNTTHPFPGKCGNNGKSSWVSDMKKLPSAPKNRDIRCECSDRPSLARGMPGERVCRCDYDC	66	Putative defensin-like protein 225 (Protein SCRL1; SCR-like protein 1; Plant defensin)	P82620	Belongs to the DEFL family	SCRL1	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00663	KTKWGCDMNRPFPGKCGTNGKDTCISDIKKMPGAPKDLVVRCECSQRFVWKGYPPERLCKCQYDC	65	Defensin-like protein 226 (Protein SCRL2; SCR-like protein 2; Plant defensin)	P82621	Belongs to the DEFL family	SCRL2	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00664	IHVEQAGVCEFTGEFPGKCGNNGRKMCVEAMNKKNKGSPGENKKNLRCECFDNPVVILGRPKRICRCRNNC	71	Putative defensin-like protein 227 (Protein SCRL28; SCR-like protein 28; Plant defensin)	P82647	Belongs to the DEFL family	SCRL28	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00665	ANKRCHLNQMFTGKCGNDGNKACLGDFKNKRFRYDLCQCTDATQISPSLPPQRVCNCSRPC	61	Putative defensin-like protein 228 (Protein SCRL3; SCR-like protein 3; Plant defensin)	P82622	Belongs to the DEFL family	SCRL3	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00666	HVREVKSVETKAKRVKKVCEKAQVFEQNCGWDGNKTCIRGFNKIKEYPFHCECGIYDAPNSRRICKCKFPYSPC	74	Defensin-like protein 229 (Protein SCRL27; SCR-like protein 27; Plant defensin)	P82646	Belongs to the DEFL family	SCRL27	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity).
Tissue specificity: Flower buds. "	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00667	EKLCTTIGDLDGKCSQDGEKLCMRYMTDQSKKKFLSCTCNNVVMLHKYKHYCECQSHCTPKQT	63	Putative defensin-like protein 230 (Protein SCRL24; SCR-like protein 24; Plant defensin)	P82643	Belongs to the DEFL family	SCRL24	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00668	KELCNRIEDIDGNCDFEGEKGCLKFMTNKYKKERHVSCTCTNLYMLHKTKRFCDCKHRCSG	61	Putative defensin-like protein 231 (Protein SCRL25; SCR-like protein 25; Plant defensin)	P82644	Belongs to the DEFL family	SCRL25	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00669	GAPPVECWSEILFSGKCGFHGKKKCYKEMESKLKQRVLKCRCEDVKKDSNTSKDEHYCGCQRENPYECN	69	Defensin-like protein 232 (Protein SCRL23; SCR-like protein 23; Plant defensin)	P82642	Belongs to the DEFL family	SCRL23	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity).
Tissue specificity: Flower buds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00670	GAPPQDCWNLVTFPAKCGIHGKKKCFKEMESKYQQRFLQCTCKNLKPEPKSPKDEHDCTCQRANPYECNS	70	Putative defensin-like protein 233 (Protein SCRL22; SCR-like protein 22; Plant defensin)	P82641	Belongs to the DEFL family	SCRL22	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity).
Tissue specificity: Expressed at least in stem, root, rosette leaves and flower buds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00671	VLKPMDQCGRKDIFLGGCGSNGSKTCINDFVKKGGVAAKPSSCECDDFGEEHLCRCYVPC	60	Putative defensin-like protein 234 (Protein SCRL14; SCR-like protein 14; Plant defensin)	P82633	Belongs to the DEFL family	SCRL14	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00672	GLDPMAANLRVRKDIFIGGCGRDGNKTCMKDFVKKGGVMNKPISCECDNLGYEHLCRCNFS	61	Putative defensin-like protein 235 (Protein SCRL26; SCR-like protein 26; Plant defensin)	P82645	Belongs to the DEFL family	SCRL26	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Defense response to fungus.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00673	QGKKKPPCPLGLSANGKCGHDGPKLCFSEMERKFNKDVVKTITHCKCWDDRRNNVDKHRCTCYLKHGFPCTNG	73	Putative defensin-like protein 236 (Protein SCRL20; SCR-like protein 20; Plant defensin)	P82639	Belongs to the DEFL family	SCRL20	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00674	QAKKKRCPIGLHTYGKCGTDRAKFCFSEIESKLSFSKQVLNTISSCRCDDDRQGNKDLYWCQCDRREGRPCPAN	74	Putative defensin-like protein 237 (Protein SCRL21; SCR-like protein 21; Plant defensin)	"P82640, F4JMF8"	Belongs to the DEFL family	SCRL21	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00675	QVKPTGCQGGQRYRGKCGTNGTKTCVKDMMLPKLFKTKRCDCQDMLGTFKGWHFCTCYSGRPGC	64	Putative defensin-like protein 238 (Protein SCRL16; SCR-like protein 16; Plant defensin)	P82635	Belongs to the DEFL family	SCRL16	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00676	GLIRECDYTMEGYGPCGPNGRSLCLDTFWKTPPSPGLSKNLEGCRCEDRGKRPPIFTGLSHTCRCCWSYGGGSDD	75	Putative defensin-like protein 239 (Protein SCRL17; SCR-like protein 17; Plant defensin)	P82636	Belongs to the DEFL family	SCRL17	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00677	GLVRICNHRIEGYGTCGPNGRKICLDAFWKNQPSPGLSKNLEGCQCEDRRKRPQFKGLSHSCSCCWSYQGNSDE	74	Putative defensin-like protein 240 (Protein SCRL18; SCR-like protein 18; Plant defensin)	P82637	Belongs to the DEFL family	SCRL18	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00678	RTIRICDRKVEGNGTCGPNSNNICLDEFWKNPPSPRLAKSLEGCTCEPRGKRPKFKGLSHVCWCCWSYNSSNPAG	75	Defensin-like protein 241 (Protein SCRL19; SCR-like protein 19; Plant defensin)	P82638	Belongs to the DEFL family	SCRL19	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00679	HEEPKVAPTEELMFAPSNQPRYCRSRQVFDGSCTDRGTPRTTCFLDFLGARSASEMPKNCDCTPQPNNKRLCECSVICTDCCVKN	85	Defensin-like protein 242 (Protein SCRL10; SCR-like protein 10; Plant defensin)	"P82629, Q6GKW3"	Belongs to the DEFL family	SCRL10	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00680	HLSHEEPMKEPEYCRWTNAFNGTCSDRGNPQTMCFFDFLDAHTARVMPKNCACNDLPGNKRYCECSFVCNS	71	Putative defensin-like protein 243 (Protein SCRL9; SCR-like protein 9; Plant defensin)	P82628	Belongs to the DEFL family	SCRL9	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00681	KELKWCPSKDVFNGSCTDTGSPSYTCFLDLLGSKSASAMPKNCKCTPLPHNRRQCDCFVVCDSN	64	Putative defensin-like protein 244 (Protein SCRL11; SCR-like protein 11; Plant defensin)	P82630	Belongs to the DEFL family	SCRL11	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00682	EESSMNIDAQRRPWCPSKKQVFGGSCGNDGAQQCLNNLLSTWDPSVRLSPVSCNCTPQPNNNILCSCPNMICP	73	Defensin-like protein 245 (Protein SCRL4; SCR-like protein 4; Plant defensin)	"P82623, A0MJS7, A7RED2"	Belongs to the DEFL family	SCRL4	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity).
Tissue specificity: Flower buds and roots."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00683	EESRMNINAERRPWCPSKIQMFDTNCEVDGAKQCLDLLISTWDPSVRLTRVSCICSDFPYRNMMCSCPNMICP	73	Defensin-like protein 246 (Protein SCRL5; SCR-like protein 5; Plant defensin)	"P82624, Q1PFI3, Q5XVH8"	Belongs to the DEFL family	SCRL5	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity).
Tissue specificity: Flower buds and stems."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00684	EKLSMDPTRRPWCPSKKQMFGGNCGNDGDSLCLMLLAASWDESLRHSSISCNCTTYPNYKILCSCPNMICP	71	Defensin-like protein 247 (Protein SCRL6; SCR-like protein 6; Plant defensin)	"P82625, Q570C5, Q8L952"	Belongs to the DEFL family	SCRL6	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00685	EAAGERRQWCPSKQQVFRGSCSDDGGQKCLNDLLWTWNPSVRLSPIYCDCTPKRHNKRLCDCPSMICL	68	Defensin-like protein 249 (Protein SCRL7; SCR-like protein 7; Plant defensin)	"P82626, A7RED3"	Belongs to the DEFL family	SCRL7	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00686	EKRPWCPTRKQIFDGSCNRTDYTQCFNDLRNTWDDIGDLCPTDCTCTPQPQNKRLCYCRYLPCPST	66	Defensin-like protein 250 (Protein SCRL8; CR-like protein 8; Plant defensin)	P82627	Belongs to the DEFL family	SCRL8	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00687	QRLVPLCKTIGYENPGKCPADGNKFCRRKLDDRYVKYKRCDCQDTKGRKQNHHRCICYMKLPCNQ	65	Putative defensin-like protein 251 (Protein SCRL12; SCR-like protein 12; Plant defensin)	P82631	Belongs to the DEFL family	SCRL12	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00688	QRRKPVCKLTGVLNPGKCPTAIHDASNLCSRKLASPNMTFKRCDCQNTEWRGKDHYQCTCYIKLPCNQ	68	Putative defensin-like protein 252 (Protein SCRL13; SCR-like protein 13; Plant defensin)	P82632	Belongs to the DEFL family	SCRL13	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00689	EVEPVPYCKVITWYDVKCGADGNKTCVDHLIKGHIYDVPVCDCSELTTSGILCTCQHRFPCKEPPPLHRISIRKQIRG	78	Putative defensin-like protein 253 (Protein SCRL15; SCR-like protein 15; Plant defensin)	P82634	Belongs to the DEFL family	SCRL15	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00690	VRHNLAVGDVCATNEECRINCQCDAAYCDLSCNMCVYMLHVMDTIDANIPNQPCISEYQNCGKKTSSLQ	69	Putative defensin-like protein 254 (Plant defensin)	Q2V318	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains two disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00691	YEDSCSTDEECRRNCLCDVAYCDKSRDKCDYGFMNRVDVRFPKHPYISKNKDGSGR	56	Defensin-like protein 255 (Plant defensin)	Q2V3Q8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains two disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00692	VADYCNRDADCKRVCLRPYACNLTRHLCMCHPNDVSSSKQHCIPEHKGFGEGGPPPQRLKLYR	63	Putative defensin-like protein 256 (Plant defensin)	Q2V483	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00693	RELAGVNEIFEIAARSSNNAGTARALQQAPPCKRDVDCSFECPKGGFCNDRLGTCDCF	58	Putative defensin-like protein 257 (Plant defensin)	Q2V3S8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00694	RELTGAGKKLEVATRSSNYAGTARTLLQARPCQRDVDCNFQCPRIQGGQCNNHHGTCDCF	60	Putative defensin-like protein 258 (Plant defensin)	Q2V3S7	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00695	RKLTGVADVIVEGEAASPQYGIIDENDTLNKSPSCKRDIDCTFQCRRGGFCNLILQKCECL	61	Defensin-like protein 259 (Plant defensin)	"Q9LV55, A0MEY0"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00696	IQNSETSVNQNSCMPNEPRCTGCPGGGSGGYRGPPPPCCKNDSDCKAHCPEGGYCSNQCDCVCNLVKVMNNDVRCQVDTDCNMKCSKQGYCKLAS	95	Defensin-like protein 260 (Plant defensin)	Q9LMX3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00697	REMVKAEVNCIGGKCPEGKKNCNCMPPIAHVMDDIRPCNTDGDCYKFCPRECELGTCYCRCDYGCTCTC	69	Putative defensin-like protein 262 (Plant defensin)	Q2V4E0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00698	REMAKEEVNCIGGHCPDGKKDCNCLPLIAPTMDIYETNESCRTDNECIKYCPKGCKIVDCNFGTCLCEYC	70	Putative defensin-like protein 263 (Plant defensin)	Q2V4D9	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00699	LEGESKVSGQVRDETPHTWYCKYDDNCRENCPGCTITKCNYGVCICSNCYHQQSDLGVESHM	62	Putative defensin-like protein 264 (Plant defensin)	Q2V2W3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00700	SKGEEKTSGELRDVTPQRGGPCSYDNLCHNHCPGCKITQCVNGECVCLICYTPPL	55	Putative defensin-like protein 265 (Plant defensin)	Q2V2W2	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00701	SEQRTRVSEVVREAEIHDGGQCTDDDICNKNCLDCIARQCIFQQCVCSKRFFPPNSQPNLRVKKH	65	Defensin-like protein 267 (Plant defensin)	Q2V354	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00702	IPRGWQEPCFCPSKNPYCDCGDDLQVPTTSVISPKPIIEQCARCERNSQCNKVCPATCKYKVCIFNRTCEFSTCHCYRC	79	Defensin-like protein 268 (Plant defensin)	"Q2V4N6, A0MJU3"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00703	RMSGDVTIQRGGSCNNDNTCHDTCPGCRITQCIFRQCVCTRCNTPRSSLRIESHM	55	Defensin-like protein 266 (Plant defensin)	Q2V4F0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00704	RQMQRPQNVECVGGECQPKHPQQYFGSCFRDSDCRNSCFPYCRYQKCHHHECICSLCSSEVAPSPK	66	Defensin-like protein 269 (Plant defensin)	Q2V4F4	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00705	TRIMDDSSDCVFKGPCQRRSDCYERCGLKPPSRAALCQPMGLQGRVCCCL	50	Putative defensin-like protein 270 (Plant defensin)	Q2V2Z3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00706	TRIMDASSDCEFKGPCHKKEDCYDSCGVNKPPFNNAICVPGRDSFQCCCILS	52	Putative defensin-like protein 271 (Plant defensin)	Q2V352	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00707	TREILSAEICGWNDPAVHCKTKEDCFEKCGGRPAKKVFCVRPGDHSYDRLCCCRA	55	Defensin-like protein 272 (Plant defensin)	Q2V2W8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00708	NSVEKDVMDGPCRLRGTCNNDGDCDKHCHRSTDAAAMDGHCLFDKPTGPVCCCLFD	56	Putative defensin-like protein 274 (Plant defensin)	Q2V2W7	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00709	KIVKRMQVGPSECVYRGRCRDSYECRSRCGPPEFSHETLGLCMFDYDDYEYFCCCTTNY	59	Defensin-like protein 275 (Plant defensin)	Q2V4I9	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00710	SGCNFKGSCRTDDQCKRICRGHGLDPSFQLCVPYSSKGGKCCCLHYEGAPLSSEVI	56	Defensin-like protein 276 (Plant defensin)	Q2V328	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00711	IVCNFEGHCVTSDDCINVCKSGEDPFLCVRSGPHKGMCCCLKTNGSVLE	49	Putative defensin-like protein 277 (Plant defensin)	Q2V329	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00712	ARIQESTNDILKPITCNTNADCAKFCKGPIHNCVYHTCQCVPGNPHCC	48	Defensin-like protein 278 (Plant defensin)	Q2V4F7	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00713	QESKKGILLKPKTCNTNADCAKFCKGPIQNCLYHTCACVPGNPHCC	46	Putative defensin-like protein 279 (Plant defensin)	Q2V4F6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00714	DYKFHVCDPSFDEKDCDFECKEFGHPGGYCRPDRVQPRIRMCYCTDR	47	Putative defensin-like protein 280 (Plant defensin)	Q2V4C4	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00715	TDPVPTPPGLHIPCGKGFTSKECNKYCTGVGYRRGYCAPDEEYPQISSCYCKWRI	55	Defensin-like protein 281 (Plant defensin)	Q2V4C3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00716	NRQCVQAMDCTNVCSHGGLCTKNGKCVCWSPNVVINSGPPCWSDEMCFSTCGGNGGYCNYDIGGCFCQ	68	Putative defensin-like protein 282 (Plant defensin)	Q2V2Y0	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00717	TAARENLHHQCFCESPSKCDCFPTTPTPPTSVNKSRKGGPLCTTDGDCKHFCRPKKGVCNIDFETCICQ	69	Putative defensin-like protein 283 (Plant defensin)	Q2L6T1	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00718	KEDKECNDSKCLPNPSRINLEEGNIKRIDVNHGGICDTYLECGGLACSDYRRACCVNGKCVCRKQGQTLPDCPN	74	Defensin-like protein 285 (Plant defensin)	"Q2V315, F4KBR3"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00719	LDEPNMDTISKSREYKCKIDLDCSNHIACRHCSYRNCKCDHGTCKCMP	48	Defensin-like protein 286 (Plant defensin)	Q2L6T6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00720	AEEMGKGEVTISLRCKTKTECLKNIACEACVDCRCDKGICKCHGFTAETNNPTV	54	Defensin-like protein 287 (Plant defensin)	Q2V4N4	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00721	KPRGKRPQSNFHAKRIRTVLQTLLVMLCTDYRCDKGLCKCHGFGGEKENPTAAPLTA	57	Putative defensin-like protein 288 (Plant defensin)	Q2V4N5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00722	DASCLTTKECVVRCSDEDAQCIHGECHCPHLKVDIEPTKAIRCKTDLDCPDPHQCPKYDYYACLNNGECTCISV	74	Defensin-like protein 289 (Plant defensin)	Q2V4I2	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains six disulfide bonds (By similarity).
Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00723	TSSTLKESLTAEIKPTKVDRCKTDRDCPQSHRCQKDFYYGCVVGECICRAV	51	Defensin-like protein 291 (Plant defensin)	Q2V472	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00724	MLLETDASRNKPSSYIPLCGSDNSCGGLWCPRKGGKYSCISMTCDIQEDCPKLVRCKDSPGPYCMEGFCTC	71	Defensin-like protein 292 (Plant defensin; Uncertain)	P0CAY8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks the signal peptide and 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00725	SRNKLSSYIPLCGSNTYCGGLWCPKKGGKYSCISMSCDIQEDCPKLVRCKNSPGPYCMEGFCTC	64	Defensin-like protein 293 (Plant defensin)	Q2V4A3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00726	SKNKSRSDLPLCGFREHCDGLWCPGEGGKYSCINWSCNFIEDCEKRIRCEKTGPCCFDGLCDCTNF	66	Defensin-like protein 294 (Plant defensin)	Q2V4A4	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00727	HNFLPCVITNDCEYHHCSSGTVLCVNRQCHCSRSSTHQTKLDNLKKMDYAKKCKWTKDCDPRMRFTCVSGSYMCFDGLCTCTN	83	Defensin-like protein 295 (Plant defensin)	Q4VNZ6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains six disulfide bonds (By similarity).
Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00728	ELVLPCKTTYDCVNLPCLGRPPLCINGQCKCTTTLTHQAKLDNLRTMNDAKTCKYTSDCDPRMRYSCVSGSYICLNGFCTCT	82	Defensin-like protein 296 (Plant defensin)	Q4VNZ5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains six disulfide bonds (By similarity).
Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00729	QLIVPCKTSEQCKSIRCSNGSAQCVNKQCQCPSLKQIYSVTDVSCKTVSDCVASHQCPTGLSACIEGKCICLP	73	Putative defensin-like protein 298 (Plant defensin)	Q2V459	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains six disulfide bonds (By similarity).
Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00730	QFRCKSVAECDSRGCRVGTHVICNEHHICTCAHGSPIGGQCDGVEDCDLSGCPPNSHVICDRIGGNFCTCVPN	73	Defensin-like protein 301 (Plant defensin)	Q3E715	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains six disulfide bonds (By similarity).
Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00731	MLRFVLVYIPVSVVSHTLCISLFIICSTRHTCFSKRYTCLLNICFCFFISSRIRNYF	57	Defensin-like protein 302 (Plant defensin)	Q2V3W5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks the signal peptide and 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00732	RCYTNDDCKDGQPCPVPLACLFGSCICPWKSQSKLPICQIICANLD	46	Putative defensin-like protein 303 (Plant defensin)	Q2V311	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00733	VRLTENMCFKDDDCINQGEWCPVLRVCSYAECICPWGTRSKLPSCQIICAHLDKKSVNSYNPCGCNYK	68	Putative defensin-like protein 304 (Plant defensin)	Q2V309	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00734	KTNFDCVNLKCPTPFVTPKCVSGGCECPLKELLTLLSDTNYGVAACIDYCKAKGENAYTCILNHCYCRKPSM	72	Putative defensin-like protein 305 (Plant defensin)	Q2V493	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00735	QSCNNDSDCTNLKCATKNIKCEQNKCQCLDERYIRAISLNTRSPRCNVQSCIDHCKAIGEVIYVCFTYHCYCRKPPM	77	Defensin-like protein 306 (Plant defensin)	Q2V3H6	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00736	RTGYVSCKTNSDCVKLKCPTPFGGPKCISGSCECPFKELMTLPNDTNYGVAACIDYCKAKGEIVYACILNHCYSYKPPM	79	Putative defensin-like protein 307 (Plant defensin)	Q2V3H5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00737	MIMGVSYHENRCHDWVDCAIWCKQWVPQPKCINRVCDCKPKSLPTNDEIPKSASSSSKN	59	Defensin-like protein 308 (Plant defensin)	Q4VP04	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00738	MIMGVHYHEYRCHDWVDCAIWCKQWVPQPKCINRVCDCKPKSLPTNEEVPQSAYSSNSNY	60	Putative defensin-like protein 309 (Plant defensin)	Q2V310	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00739	DICQTDRDCVEIGIPRCKRTGKMPICYNGYCCCICSAKRLPASTTRKPPSPSTSKLV	57	Defensin-like protein 311 (Plant defensin)	Q2V3X3	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00740	QSPLSQSSHEFTVVSPYLSCFGIEECLFYLYFKLYDLCVILLCTWFDLSE	50	Putative defensin-like protein 312 (Plant defensin)	Q2V3K9	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Caution: Could be the product of a pseudogene. Lacks 3 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00741	HVCLMSFGSSYRVGVHITHEKVAACPRQNQRLYSCDSLRILYHYSCLTTRDLLYICDCSDFENIICLIRLLLNLDFVEVKLV	82	Defensin-like protein 316 (Plant defensin)	Q2V4J8	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00742	FKIHEVPEPTGKWCGYSVPMKPCINDDRVKRCIAENTHGWLMATGMCTSIPSLKDCYCMHQCP	63	Putative defensin-like protein 317 (Plant defensin)	Q2V3Y5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00743	DCKHPVGPYTDSCFTDCVSGKYGYNYESAFCSRDETGTCKICCCELINE	49	Defensin-like protein 313 (Plant defensin)	"Q3E8K0, Q1PDQ0"	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: May have antifungal activity.
PTM: Contains three disulfide bonds (By similarity).
Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11437247##15955924	Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.	"Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00744	MYLSSRTGSRLLFLVKASFNTFEKVATISSTLIYFVSHKLVSSRSCSHNFRNICGYIRHNCRKCIRFCFCTFSIKISLPLVIARRIEY	88	Putative defensin-like protein 315 (Plant defensin)	Q2V3R5	Belongs to the DEFL family	Not found	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"PTM: Contains two disulfide bonds (By similarity).
Caution: Could be the product of a pseudogene. Lacks the signal peptide and 2 of the 4 disulfide bonds, which are conserved features of the family."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15955924	Plant Physiol. 2005 Jun;138(2):600-610.	"Silverstein KA, Graham MA, Paape TD, VandenBosch KA."	Genome organization of more than 300 defensin-like genes in Arabidopsis.
DRAMP00745	GTCKAECPTWEGICINKAPCVKCCKAQPEKFTDGHCSKILRRCLCTKPC	49	Floral defensin-like protein 2 (PhD2; Plant defensin)	Q8H6Q0	Belongs to the DEFL family	D2	Petunia hybrida (Petunia)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Plant defense peptide with antifungal activity against F. oxysporum and Botrytis cinerea.
Tissue specificity: Petals.
Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin (By similarity).
Biophysicochemical properties: pH dependence (Stable under extremes of pH); Temperature dependence (Stable under extremes of temperature).
PTM: Contains five disulfide bonds 3-49; 7-23; 14-36; 20-43; 24-45 (By similarity)."	"Fungi: Fusarium oxysporum (86% inhibition at 10 ?g/ml), Botrytis cinerea (41% inhibition at 10 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12644678	Plant Physiol. 2003 Mar;131(3):1283-1293.	"Lay FT, Brugliera F, Anderson MA."	Isolation and properties of floral defensins from ornamental tobacco and petunia.
DRAMP00746	RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC	47	Flower-specific defensin (NaD1; Plant defensin)	Q8GTM0	Belongs to the DEFL family	D1	Nicotiana alata (Winged tobacco) (Persian tobacco)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Combine helix and strand structure	NaD1 adopts the cysteine-stabilized ¦Á¦Â (CS¦Á¦Â) motif formed by a triple-stranded antiparallel ¦Â-sheet and a single ¦Á-helix that is tethered to the sheet via three disulfide bonds. The fourth disulfide bond reinforces the N- and C-terminal regions of the molecule. 	"4AAZ, 4AB0 resolved by X-ray."	"Function: NaD1 is a member of a family of cationic peptides that displays growth inhibitory activity against several filamentous fungi, including Fusarium oxysporum.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43.
Tissue specificity: Most abundant in the epidermal cell layers of the petals and sepals, within the connective cells of the anthers, and the cortical cells of the style. Not detected in the tapetum, pollen mother cells, the transmitting tissue, the vascular bundles of the anther and style or in leaves. Expressed also in ovaries, but barley detectable in roots.
Biophysicochemical properties: pH dependence (Stable under extremes of pH); Temperature dependence (Stable under extremes of temperature."	"Fungi: Fusarium oxysporum f. sp. Vasinfectum (IC50=1 ?M), Thielaviopsis basicola (IC50=0.80 ?M), Verticillium dahliae (IC50=0.75 ?M), Leptosphaeria maculans (IC50=0.80 ?M), Aspergillus nidulans (IC50=0.80 ?M), Candida albicans (IC50>10 ?M), Pichia pastoris (IC50>10 ?M), Saccharomyces cerevisiae (IC50>10 ?M).##Gram-negative bacteria: Escherichia coli (IC50>10 ?M), Pseudomonas aeruginosa (IC50>10 ?M);##Gram-positive bacteria: Staphylococcus aureus (IC50>10 ?M), Bacillus cereus (IC50>10 ?M).##HeLa cells (IC50>10 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12644678##12473460##22511788##18339623	Plant Physiol. 2003 Mar;131(3):1283-1293.##J Mol Biol. 2003 Jan 3;325(1):175-188.##J Biol Chem. 2012 Jun 8;287(24):19961-72.##J Biol Chem. 2008 May 23;283(21):14445-52.	"Lay FT, Brugliera F, Anderson MA.##Lay FT, Schirra HJ, Scanlon MJ, Anderson MA, Craik DJ.##Lay FT, Mills GD, Poon IK, Cowieson NP, Kirby N, Baxter AA, van der Weerden NL, Dogovski C, Perugini MA, Anderson MA, Kvansakul M, Hulett MD.##van der Weerden NL, Lay FT, Anderson MA."	"Isolation and properties of floral defensins from ornamental tobacco and petunia.##The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP.##Dimerization of plant defensin NaD1 enhances its antifungal activity.##The plant defensin, NaD1, enters the cytoplasm of Fusarium oxysporum hyphae."
DRAMP00747	RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKLLRRCLCTKPCVFDEKMIKTGAETLVEEAKTLAAALLEEEIMDN	80	Defensin-like protein (Flower-specific gamma-thionin; Plant defensin)	P32026	Belongs to the DEFL family	FST	Nicotiana tabacum (Common tobacco)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	Not found	1MR4 resolved by NMR.	"Function: Involved in floral organogenesis. May play a protective role in flowers by protecting the reproductive organs from potential pathogen attack.
Tissue specificity: Found in petals, stamen and pistils, but not in sepals. In particular, accumulation in a configuration surrounding the inner reproductive whorls.
Developmental stage: Accumulates in developing flowers and its level drops as flowers mature.
PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43."	Fungi: Fusarium oxysporum and Botrytis cinerea.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1495489##12473460	Mol Gen Genet. 1992 Jul;234(1):89-96.##J Mol Biol. 2003 Jan 3;325(1):175-188.	"Gu Q, Kawata EE, Morse MJ, Wu HM, Cheung AY.##Lay FT, Schirra HJ, Scanlon MJ, Anderson MA, Craik DJ."	"A flower-specific cDNA encoding a novel thionin in tobacco.##The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP."
DRAMP00748	QDKCKKVYENYPVSKCQLANQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY	54	Defensin-like protein(Brazzein; Plants)	P56552	Belongs to the DEFL family	Not found	Pentadiplandra brazzeana	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Combine helix and strand structure	"The brazzein fold, which contains one alpha-helix and three strands of antiparallel beta-sheet."	1BRZ resolved by NMR.##4HE7 resolved by X-ray.	"Function: Taste-modifying protein; sweet-tasting. It is 2000 sweeter than sucrose on a molar basis. Has a pH-specific antimicrobial activity against bacteria and fungi. 
PTM: Contains four disulfide bonds 4-52; 16-37; 22-47; 26-49."	"Gram-positive bacteria: Bacillus subtilis, Staphylococcus aureus.##Gram-positive bacterium: Escherichia coli.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15118082##9628478	Proc Natl Acad Sci U S A. 2004 May 11;101(19):7363-7368.##Nat Struct Biol. 1998 Jun;5(6):427-431.	"Yount NY, Yeaman MR.##Caldwell JE, Abildgaard F, Dzakula Z, Ming D, Hellekant G, Markley JL."	Multidimensional signatures in antimicrobial peptides.##Solution structure of the thermostable sweet-tasting protein brazzein.
DRAMP00749	ELCEKASKTWSGNCGNTGHCDNQCKSWEGAAHGACHVRNGKHMCFCYFNC	50	Defensin-like protein 1 (Dm-AMP1; Plant defensin)	P0C8Y4	Belongs to the DEFL family	Not found	Dahlia merckii (Bedding dahlia)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	"Function: Possesses antimicrobial activity sensitive to inorganic cations. Has no inhibitory effect on insect gut alpha-amylase. Induces potential changes in fungal membranes and increased K+ efflux and Ca2+ uptake. Interacts with sphingolipids and ergosterols found in fungal plasma membranes. 
Biotechnological use: DmAMP1 expression in heterologous plants such as rice or papaya may provide a broad-spectrum disease resistance.
PTM: Problely contains four disulfide bonds 3-50;14-35;20-44;24-46."	"Gram-positive bacterium: Bacillus subtilis (IC50=150 ?g/mL).##Medium A: Botrytis cinerea (IC50=12 ?g/ml), Cladosporium sphaerospermum (IC50=3 ?g/ml), Fusarium culmorum (IC50=5 ?g/ml), Leptosphaeria maculans (IC50=1.5 ?g/ml), Penicillium digitatum (IC50=2 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=1 ?g/ml), Verticilium albo-atrum (IC50=4 ?g/ml). NOTE: Medium B = 1/2 strength potato dextrose broth.##Medium B: Botrytis cinerea (IC50>100 ?g/ml), Cladosporium sphaerospermum (IC50=12 ?g/ml), Fusarium culmorum (IC50=8 ?g/ml), Leptosphaeria maculans (IC50=15 ?g/ml), Penicillium digitatum (IC50=70 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=4 ?g/ml), Verticilium albo-atrum (IC50>100 ?g/ml).##NOTE: Medium B = Medium A supplemented with 1 mM CaCl2 and 50 mM KCI."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	cell membrabce	13129623##7628617##8663029##17216480	FEMS Microbiol Lett. 2003 Sep 12;226(1):169-173.##FEBS Lett. 1995 Jul 17;368(2):257-262.##Plant Physiol. 2002 Apr;128(4):1346-1358.##J Biol Chem. 1996 Jun 21;271(25):15018-15025.##Planta. 2007 Jun;226(1):87-97	"Thevissen K, Fran¡ìois IE, Takemoto JY, Ferket KK, Meert EM, Cammue BP.##Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF.##Fran¡ìois IE, De Bolle MF, Dwyer G, Goderis IJ, Woutors PF, Verhaert PD, Proost P, Schaaper WM, Cammue BP, Broekaert WF.##Thevissen K, Ghazi A, De Samblanx GW, Brownlee C, Osborn RW, Broekaert WF.##Zhu YJ, Agbayani R, Moore PH."	"DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckii), interacts with sphingolipids from Saccharomyces cerevisiae.##Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae.##Fungal membrane responses induced by plant defensins and thionins.##Ectopic expression of Dahlia merckii defensin DmAMP1 improves papaya resistance to Phytophthora palmivora by reducing pathogen vigor."
DRAMP00750	EVCEKASKTWSGNCGNTGHC	20	Defensin-like protein 2 (Dm-AMP2; Plant defensin)	No entry found	Belongs to the DEFL family	Not found	Dahlia merckii (Bedding dahlia)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Medium A: Botrytis cinerea (IC50=10 ?g/ml), Cladosporium sphaerospermum (IC50=3 ?g/ml), Fusarium culmorum (IC50=5 ?g/ml), Leptosphaeria maculans (IC50=1 ?g/ml), Penicillium digitatum (IC50=2 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=1 ?g/ml), Verticilium albo-atrum (IC50=2 ?g/ml). NOTE: Medium A = 1/2 strength potato dextrose broth.##Medium B: Botrytis cinerea (IC50>100 ?g/ml), Cladosporium sphaerospermum (IC50=12 ?g/ml), Fusarium culmorum (IC50=12 ?g/ml), Leptosphaeria maculans (IC50=20 ?g/ml), Penicillium digitatum (IC50=50 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=2 ?g/ml), Verticilium albo-atrum (IC50>100 ?g/ml).##NOTE: Medium B = Medium A supplemented with 1 mM CaCl2 and 50 mM KCI."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	cell membrabce	8422949##7628617	FEBS Lett. 1993 Feb 1;316(3):233-240.##FEBS Lett. 1995 Jul 17;368(2):257-262.	"Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF."	"A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae."
DRAMP00751	RMCKTPSAKFKGYCVSSTNCKNVCRTEGFPTGSCDFHITSRKCYCYKPCP	50	Defensin-2 (Plant defensin)	A4L7R8	Belongs to the DEFL family	Def2	Pinus sylvestris (Scots pine)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	"Function: Plant defense peptide. Has antifungal activity.
PTM: Contains three disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19253756	Tsitol Genet. 2008 Nov-Dec;42(6):55-60.	"Koval'ova VA, Hut RT."	Molecular cloning and characterization of Scotch pine Defensin-2.
DRAMP00752	RMCKTPSGKFKGYCVNNTNCKNVCRTEGFPTGSCDFHVAGRKCYCYKPCP	50	"PsDef1 (P. sylvestris defensin 1, p1; Plant defensin)"	A4L7R7	Belongs to the DEFL family	Def1	Pinus sylvestris (Scots pine)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Plant defense peptide. Has antifungal activity.
PTM: Contains four disulfide bonds (By similarity)."	"Fungi: Botrytis cinerea (IC50=0.4 ?g/ml), Fusarium oxysporum (IC50=2.9 ?g/ml), Fusarium solani (IC50=0.9 ?g/ml), Heterobasidion annosum (IC50=1.4 ?g/ml), Candida albicans and Trichoderma reesei."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19683554	Peptides. 2009 Dec;30(12):2136-2143.	"Kovaleva V, Kiyamova R, Cramer R, Krynytskyy H, Gout I, Filonenko V, Gout R."	Purification and molecular cloning of antimicrobial peptides from Scots pine seedlings.
DRAMP00753	ATKVKAKQRGKEKVSSGRPGQHN	23	Elicitor peptide 1 (AtPep1; Plant defensin)	"Q9LV87, Q8LCK9"	Belongs to the brassicaceae elicitor peptide family	PEP1	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Protein level	Not found	"Sequential removal of N-terminal amino acids has little effect on activity. Activity is completely abolished when nine C-terminal amino acids remained. Removal of the C-terminal asparagine from AtPep1(9-23), resultes in a decrease in activity (12 max approximately 100 nM)."	None	"Function: Elicitor of plant defense. Induces the production of plant defensin (PDF1.2) and of H2O2. Promotes resistance to the root fungal pathogen P. irregulare.
Subunit structure: Interacts with its receptor PEPR1.
Induction: By wounding, methyl jasmonate (MeJA), ethylene. The expression of the peptide PEP1 precursor is induced by the mature peptide PEP1."	Pythium irregulare	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16785434##16785433##18824048	Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10098-103.##Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10104-9.##Peptides. 2008 Dec;29(12):2083-9.	"Huffaker A, Pearce G, Ryan CA.##The cell surface leucine-rich repeat receptor for AtPep1, an endogenous peptide elicitor in Arabidopsis, is functional in transgenic tobacco cells.##Pearce G, Yamaguchi Y, Munske G, Ryan CA."	"An endogenous peptide signal in Arabidopsis activates components of the innate immune response.##The cell surface leucine-rich repeat receptor for AtPep1, an endogenous peptide elicitor in Arabidopsis, is functional in transgenic tobacco cells.##Structure-activity studies of AtPep1, a plant peptide signal involved in the innate immune response."
DRAMP00760	RECKAQGRHGTCFRDANCVQVCEKQAGWSHGDCRAQFKCKCIFEC	45	NmDef02 (Plants)	No entry found	Belongs to the defensin family	Not found	Nicotiana megalosiphon	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Transgenic plants: Constitutive expression of NmDef02 gene in transgenic tobacco and potato plants enhanced resistance against various plant microbial pathogens, including the oomycete Phytophthora infestans, causal agent of the economically important pot"	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20626828	Plant Biotechnol J. 2010 Aug;8(6):678-690.	"Portieles R, Ayra C, Gonzalez E, Gallo A, Rodriguez R, Chac?n O, L?pez Y, Rodriguez M, Castillo J, Pujol M, Enriquez G, Borroto C, Trujillo L, Thomma BP, Borr?s-Hidalgo O."	"NmDef02, a novel antimicrobial gene isolated from Nicotiana megalosiphon confers high-level pathogen resistance under greenhouse and field conditions."
DRAMP00762	GLPVCGETCFGGTCNTPGCTCDPWPVCTRN	30	Vaby D (Plant defensin)	No entry found	Not found	Not found	Viola abyssinica (Ethiopian highlands)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Bridge	Not found	None	PTM: Contains three disulfide bonds	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21434649	J Nat Prod. 2011 Apr 25;74(4):727-731.	"Yeshak MY, Burman R, Asres K, G?ransson U."	Cyclotides from an extreme habitat: characterization of cyclic peptides from Viola abyssinica of the Ethiopian highlands.
DRAMP00763	GLPVCGETCAGGTCNTPGCSCSWPICTRN	29	Vaby A (Plant defensin)	No entry found	Not found	Not found	Viola abyssinica (Ethiopian highlands)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Bridge	Not found	None	PTM: Contains three disulfide bonds	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21434649	J Nat Prod. 2011 Apr 25;74(4):727-731.	"Yeshak MY, Burman R, Asres K, G?ransson U."	Cyclotides from an extreme habitat: characterization of cyclic peptides from Viola abyssinica of the Ethiopian highlands.
DRAMP18197	INNWVRVPPCDQVCSRSNPEKDECCRAHGHAFHAHCNGGMNCYRR	45	Diapausin-1	No entry found	Belongs to the diapausin family of peptides	Not found	"hemolymph, tobacco hornworm, Manduca sexta"	"Antimicrobial, Antifungal"		Not found	Not found	None	Function: Active against FUNGI such as S. cerevisiae (IC50 12 uM) but not bacteria.	S. cerevisiae(IC50 12 uM)	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	26976231	Dev Comp Immunol.61:258-68(2016)	"Al Souhail Q, Hiromasa Y, Rahnamaeian M, Giraldo MC, Takahashi D, Valent B, Vilcinskas A, Kanost MR."	"Characterization and regulation of expression of an antifungal peptide from hemolymph of an insect, Manduca sexta."
DRAMP00865	ESEFDRQEYEECKRQCMQLETSGQMRRCVSQCDKRFEEDIDWSKYDNQE	49	Vicilin-like Antimicrobial peptide 2a (MiAMP2a; Plant defensin)	Q9SPL5	Belongs to the vicilin-like family	AMP2-1	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database.	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml).##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP00932	SYFSAWAGPGCNNHNARYSKCGCSNIGHNVHGGYEFVYQGQTAAAYNTDNCKGVAQTRFSSSVNQACSNFGWKSVFIQC	79	Antimicrobial peptide 1 (PMAP1; Plant defensin)	P83880	Not found	Not found	Pinus monticola (Western white pine) (Strobus monticola)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Bridge 	Not found	None	"Tissue specificity: Detected at higher levels in needles and twigs from canker-resistant seedlings than in needles from canker-susceptible plants. During summer, detected on cankered, healthy and marginal bark. During winter, detected at lower levels in cankered bark and bark from the canker margin than in healthy bark (at protein level).
Developmental stage: In summer, present at higher levels in older needles and twigs than in tissues from the current year. In winter, detected at high levels in both older and current-year needles and twigs. Induction: By wounding and by methyl jasmonate.
PTM: Problely contains three disulfide bonds 11-67; 21-79; 23-51."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18943919##14759906 	Phytopathology. 2006 Feb;96(2):164-170.##Tree Physiol. 1997 Oct;17(10):663-669.	"Ekramoddoullah AK, Liu JJ, Zamani A.##Davidson J, Ekramoddoullah AK."	Cloning and Characterization of a Putative Antifungal Peptide Gene (Pm-AMP1) in Pinus monticola.##Analysis of bark proteins in blister rust-resistant and susceptible western white pine (Pinus monticola).
DRAMP00934	RTCESQSHRFKGTCVRQSNCAAVCQTEGFHGGNCRGFRRRCFCTKHC	47	Vv-AMP1 (Vitis vinifera antimicrobial peptide 1; Plant defensin)	No entry found	Not found	Not found	Vitis vinifera (Berry)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	MOA: the inhibitory activity of Vv-AMP1 might be associated with altering the membrane permeability of the fungal membranes.	Fungi: Fusarium oxysporum and Verticillium dahliae.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18611251	BMC Plant Biol. 2008 Jul 8;8:75.	"de Beer A, Vivier MA."	"Vv-AMP1, a ripening induced peptide from Vitis vinifera shows strong antifungal activity."
DRAMP00937	KSCCRNTVARNCYNVCRIPGTPRPVCAATCDCKLITGTKCPPGYEK	46	Tu-AMP1 (Plant defensin)	No entry found	Belongs to the thionin family	Not found	Tulipa gesneriana L. 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Bacteria: Erwinia carotovora (IC50=11 ?g/ml), Agrobacterium radiobacter (IC50=15 ?g/ml), Agrobacterium rhizogenes (IC50=20 ?g/ml);##Gram-positive bacteria: Clavibacter michiganensis (IC50=14 ?g/ml), Curtobacterium flaccumfaciens (IC50=13 ?g/ml).##Fungi: Fusarium oxysporum (IC50=2 ?g/ml), Geotrichum candidum (IC50=2 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	15056889	Biosci Biotechnol Biochem. 2004 Mar;68(3):571-577.	"Fujimura M, Ideguchi M, Minami Y, Watanabe K, Tadera K."	"Purification, characterization, and sequencing of novel antimicrobial peptides, Tu-AMP 1 and Tu-AMP 2, from bulbs of tulip (Tulipa gesneriana L.)."
DRAMP00938	KSCCRNTTARNCYNVCRIPG	20	Tu-AMP2 (Plant defensin)	No entry found	Belongs to the thionin family	Not found	Tulipa gesneriana L. 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Erwinia carotovora (IC50=15 ?g/ml), Agrobacterium radiobacter (IC50=17 ?g/ml), Agrobacterium rhizogenes (IC50=20 ?g/ml);##Gram-positive bacteria: Clavibacter michiganensis (IC50=17 ?g/ml), Curtobacterium flaccumfaciens (IC50=15 ?g/ml).##Fungi: Fusarium oxysporum (IC50=2 ?g/ml), Geotrichum candidum (IC50=2 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15056889	Biosci Biotechnol Biochem. 2004 Mar;68(3):571-577.	"Fujimura M, Ideguchi M, Minami Y, Watanabe K, Tadera K."	"Purification, characterization, and sequencing of novel antimicrobial peptides, Tu-AMP 1 and Tu-AMP 2, from bulbs of tulip (Tulipa gesneriana L.)."
DRAMP00952	KSCCPNTTGRNIYNTCRLTGSSRETCAKLSGCKIISASTCPSNYPK	46	Viscotoxin A1 (Plant defensin)	D0VWT3	Not found	Not found	Viscum album (European mistletoe)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Protein level	Combine helix and strand structure	Not found	3C8P resolved by X-ray.	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18703848	Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):985-992.	"Pal A, Debreczeni JE, Sevvana M, Gruene T, Kahle B, Zeeck A, Sheldrick GM."	Structures of viscotoxins A1 and B2 from European mistletoe solved using native data alone.
DRAMP00954	KSCCPNTTGRNIYNACRLTGAPRPTCAKLSGCKIISGSTCPSDYPK	46	Viscotoxin-A3 (Plant defensin)	P01538	Belongs to the thionin family	THI2.1	Viscum album (European mistletoe)	"Antimicrobial, Antifungal, Cytotoxic"	Protein level	Combine helix and strand structure	Not found	1OKH resolved by X-ray.	"Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane.
PTM: Contains three disulfide bonds 3-40; 4-32; 16-26. "	"Fungi: Fusarium solani, Sclerotinia sclerotiorum, Phytophtora infestans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrance	1710983##4941626##10947973	Eur J Biochem. 1991 Jun 15;198(3):549-553.##Acta Chem Scand. 1971;25(6):2048-2054.##Biochem J. 2000 Sep 1;350 Pt 2:569-577.	"Schrader G, Apel K.##Samuelsson G, Pettersson B.##Romagnoli S, Ugolini R, Fogolari F, Schaller G, Urech K, Giannattasio M, Ragona L, Molinari H."	"Isolation and characterization of cDNAs encoding viscotoxins of mistletoe (Viscum album).##The disulfide bonds of viscotoxin A3 from the European mistletoe (Viscum album L., Loranthaceae).##NMR structural determination of viscotoxin A3 from Viscum album L."
DRAMP00955	KSCCPNTTGRNIYNTCRLGGGSRERCASLSGCKIISASTCPSDYPK	46	Viscotoxin-B (VtB; Plant defensin)	"P08943, P01536, P84186"	Belongs to the thionin family	THI2.2	Viscum album (European mistletoe)	"Antimicrobial, Antifungal, Cytotoxic"	Protein level	Combine helix and strand structure	Not found	1JMP resolved by NMR.##2V9B resolved by X-ray.	"Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise Function: is not known.
PTM: Contains three disulfide bonds 3-40; 4-32; 16-26."	"Fungi: Fusarium solani, Sclerotinia sclerotiorum, Phytophtora infestans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1710983##12733989	Eur J Biochem. 1991 Jun 15;198(3):549-553.##Biochem J. 2003 Aug 15;374(Pt 1):71-78.	"Schrader G, Apel K.##Coulon A, Mosbah A, Lopez A, Sautereau AM, Schaller G, Urech K, Roug? P, Darbon H."	"Isolation and characterization of cDNAs encoding viscotoxins of mistletoe (Viscum album).##Comparative membrane interaction study of viscotoxins A3, A2 and B from mistletoe (Viscum album) and connections with their structures."
DRAMP00957	KSCCRSTQARNIYNAPRFAGGSRPLCALGSGCKIVDDKKTPPND	44	Pp-AMP1 (P. pubescens AMP1; Plant defensin)	No entry found	Belongs to the thionin family	Not found	Phyllostachys pubescens (Japanese bamboo shoots)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Bridge 	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Erwinia carotovora (IC50=22 ?g/ml), Agrobacterium radiobacter (IC50=15 ?g/ml), Agrobacterium rhizogenes (IC50=15 ?g/ml);##Gram-positive bacteria: Clavibacter michiganensis (IC50=14 ?g/ml), Curtobacterium flaccumfaciens (IC50=25 ?g/ml).##Fungi: Fusarium oxysporum (IC50=2 ?g/ml), Geotrichum candidum (IC50=2 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	15784998	Biosci Biotechnol Biochem. 2005 Mar;69(3):642-645.	"Fujimura M, Ideguchi M, Minami Y, Watanabe K, Tadera K."	"Amino acid sequence and antimicrobial activity of chitin-binding peptides, Pp-AMP 1 and Pp-AMP 2, from Japanese bamboo shoots (Phyllostachys pubescens)."
DRAMP00958	KSCCRSTTARNIYNGCRVPGTARPVCAKKSGCKIQEAKKCEPPYD	45	Pp-AMP2 (P. pubescens AMP2; Plant defensin)	No entry found	Belongs to the thionin family	Not found	Phyllostachys pubescens (Japanese bamboo shoots)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Bridge 	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Erwinia carotovora (IC50=20 ?g/ml), Agrobacterium radiobacter (IC50=13 ?g/ml), Agrobacterium rhizogenes (IC50=15 ?g/ml);##Gram-positive bacteria: Clavibacter michiganensis (IC50=18 ?g/ml), Curtobacterium flaccumfaciens (IC50=20 ?g/ml).##Fungi: Fusarium oxysporum (IC50=2 ?g/ml), Geotrichum candidum (IC50=2 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	15784998	Biosci Biotechnol Biochem. 2005 Mar;69(3):642-645.	"Fujimura M, Ideguchi M, Minami Y, Watanabe K, Tadera K."	"Amino acid sequence and antimicrobial activity of chitin-binding peptides, Pp-AMP 1 and Pp-AMP 2, from Japanese bamboo shoots (Phyllostachys pubescens)."
DRAMP01380	GLFTLIKCAYQLIAPTVACN	20	"Odorranain-J1 (OdJ1; Frogs, amphibians, animals)"	A6MBN6	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Odorranain-J1 adopts 50.1% ¦Â-sheet and 13.7% turn structure in water solution.	None	Function: Odorranain-J1 exhibites moderate antimicrobial activities against Gram-positive and Gram-negative bacteria and fungi.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=35.60 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=17.80 ¦Ìg/ml), Bacillus subtilis (MIC=35.60 ¦Ìg/ml).##Yeast: Candida albicans (MIC=8.90 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP00968	KSCCKDTLARNCYNTCRFAGGSRPVCAGACRCKIISGPKCPSDYPK	46	Leaf-specific thionin BTH6 (Plant defensin)	P09618	Belongs to the thionin family	Not found	Hordeum vulgare (Barley)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane.
PTM: Contains four disulfide bonds 3-40; 4-30; 12-26; 16-26."	"Fungi: Thievaliopsis paradoxa, Drechslera teres."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16453847##PubMed ID is not available	EMBO J. 1988 Jun;7(6):1559-1565.##Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases	"Bohlmann H, Clausen S, Behnke S, Giese H, Hiller C, Reimann-Philipp U, Schrader G, Barkholt V, Apel K.##Holtorf S, Schuetz C, Apel K, Bohlmann H."	Leaf-specific thionins of barley-a novel class of cell wall proteins toxic to plant-pathogenic fungi and possibly involved in the defence mechanism of plants.##Specific and distinct expression patterns of two members of the thionin multigene family of barley in transgenic tobacco.
DRAMP00969	KSCCRSTLGRNCYNLCRVRGAQKLCAGVCRCKLTSSGKCPTGFPK	45	Alpha-hordothionin (alpha-HT; Plant defensin)	P01545	Belongs to the thionin family	THI1.1	Hordeum vulgare (Barley)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	3082629##2850969	Eur J Biochem. 1986 Apr 1;156(1):131-135.##Gene. 1988 Oct 30;70(2):271-281.	"Ponz F, Paz-Ares J, Hern?ndez-Lucas C, Garc?a-Olmedo F, Carbonero P.##Rodr?guez-Palenzuela P, Pintor-Toro JA, Carbonero P, Garc?a-Olmedo F."	Cloning and nucleotide sequence of a cDNA encoding the precursor of the barley toxin alpha-hordothionin.##Nucleotide sequence and endosperm-specific expression of the structural gene for the toxin alpha-hordothionin in barley (Hordeum vulgare L.).
DRAMP00970	KSCCRSTLGRNCYNLCRVRGAQKLCANACRCKLTSGLKCPSSFPK	45	Beta-hordothionin (beta-HT; Plant defensin)	P21742	Belongs to the thionin family	THI1.2	Hordeum vulgare (Barley)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	Not found	1WUW resolved by X-ray.	Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15848162	FEBS Lett. 2005 Apr 25;579(11):2301-2306.	"Johnson KA, Kim E, Teeter MM, Suh SW, Stec B."	Crystal structure of alpha-hordothionin at 1.9 Angstrom resolution.
DRAMP00975	RVCMKGSAGFKGLCMRDQNCAQVCLQEGWGGGNCDGVMRQCKCIRQC	47	SI alpha-2 (SIa2; Plant defensin)	No entry found	Not found	Not found	Sorghum bicolor (Seeds)	"Antimicrobial, Antifungal"	Not found	Bridge	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1995329	FEBS Lett. 1991 Feb 11;279(1):101-104.	"Bloch C Jr, Richardson M."	A new family of small (5 kDa) protein inhibitors of insect alpha-amylases from seeds or sorghum (Sorghum bicolar (L) Moench) have sequence homologies with wheat gamma-purothionins.
DRAMP00976	VGECVRGRCPSGMCCSQFGYCGKGPKYCG	29	Antimicrobial peptide 1 (AC-AMP1; Plant defensin)	P27275	Not found	Not found	Amaranthus caudatus (Love-lies-bleeding) (Inca-wheat)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	"Function: Chitin-binding protein with a defensive Function: against numerous chitin containing fungal pathogens. It is also a potent inhibitor of Gram-positive bacteria.
Miscellaneous: Its chitin-binding activity is strongly inhibited by divalent cations.
PTM: Contains three disulfide bonds 4-15; 9-21; 14-28."	"Gram-positive bacteria: Bacillus megaterium (IC50=40 ?g/ml), Sarcina lutea (IC50=250 ?g/ml).##Fungi: Alternaria brassicola (IC50=7 ?g/ml), Ascochyta pisi (IC50=8 ?g/ml), Botrytis cinera (IC50=10 ?g/ml), Colletotrichum lindemuthianum (IC50=8 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Trichoderma hamatum (IC50=7 ?g/ml), Verticillium dahliae (IC50=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	1567877##9176817	Biochemistry. 1992 May 5;31(17):4308-4314.##J Pept Res. 1997 Apr;49(4):336-340.	"Broekaert W.F, Marien W, Terras F.R.G, de Bolle M.F.C, Proost P, van Damme J, Dillen L, Claeys M, Rees S.B, Vanderleyden J, Cammue B.P.A.##el Bouyoussfi M, Laus G, Verheyden P, Wyns L, Tourwe D, Van Binst G."	Antimicrobial peptides from Amaranthus caudatus seeds with sequence homology to the cysteine/glycine-rich domain of chitin-binding proteins.##Location of the three disulfide bonds in an antimicrobial peptide from Amaranthus caudatus using mass spectrometry.
DRAMP00977	VGECVRGRCPSGMCCSQFGYCGKGPKYCGR	30	Antimicrobial peptide 2 (AC-AMP2; Plant defensin)	P27275	Not found	Not found	Amaranthus caudatus (Love-lies-bleeding) (Inca-wheat)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Beta strand	"The main structural element is an antiparallel beta-sheet from Met13 to Lys23 including a betaI-turn over Gln17-Phel8 with a beta bulge at Gly19. In addition, a beta'I turn over Arg6-Gly7, a beta'III turn over Ser11-Gly12 and a helical turn from Gly24 to Cys28 are identified."	"1MMC, 1ZNT, 1ZUV, 1ZWU resolved by NMR."	"Function: Chitin-binding protein with a defensive Function: against numerous chitin containing fungal pathogens. It is also a potent inhibitor of Gram-positive bacteria.
Miscellaneous: Its chitin-binding activity is strongly inhibited by divalent cations.
PTM: Contains three disulfide bonds 4-15; 9-21; 14-28."	"Gram-positive bacteria: Bacillus megaterium (IC50=40 ?g/ml), Sarcina lutea (IC50=250 ?g/ml).##Fungi: Alternaria brassicola (IC50=7 ?g/ml), Ascochyta pisi (IC50=8 ?g/ml), Botrytis cinera (IC50=10 ?g/ml), Colletotrichum lindemuthianum (IC50=8 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Trichoderma hamatum (IC50=7 ?g/ml), Verticillium dahliae (IC50=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	1567877##8627629##9176817	Biochemistry. 1992 May 5;31(17):4308-4314.##J Mol Biol. 1996 May 3;258(2):322-333.##J Pept Res. 1997 Apr;49(4):336-340.	"Broekaert W.F, Marien W, Terras F.R.G, de Bolle M.F.C, Proost P, van Damme J, Dillen L, Claeys M, Rees S.B, Vanderleyden J, Cammue B.P.A.##Martins JC, Maes D, Loris R, Pepermans HA, Wyns L, Willem R, Verheyden P.##el Bouyoussfi M, Laus G, Verhey"	"Antimicrobial peptides from Amaranthus caudatus seeds with sequence homology to the cysteine/glycine-rich domain of chitin-binding proteins.##H NMR study of the solution structure of Ac-AMP2, a sugar binding antimicrobial protein isolated from Amaranthus caudatus."
DRAMP00978	QTCASRCPRPCNAGLCCSIYGYCGSGNAYCGAGNCRCQCRG	41	Antifungal peptide 1 (EAFP1; Plant defensin)	P83596	Belongs to the hevein-like family	Not found	Eucommia ulmoides (Hardy rubber tree)	"Antimicrobial, Antifungal"	Protein level	Bridge 	Not found	None	"Function: Has antifungal activity. PTM: Contain five disulfide bonds 3-17; 7-37; 11-23; 16-30; 35-39, and Pyrrolidone carboxylic acid at position 1."	"Fungi: Phytophthora infestans, Ascochyta lycopersici (IC50=155 ?g/ml), Verticillium dahliae, Gibberella zeae, Alternaria nicotianae, Fusarium moniliforme (IC50=56 ?g/ml), Fusarium oxysporum (IC50=46 ?g/ml) and Colletotrichum gossypii (IC50=35 ?g/ml). "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12067732	FEBS Lett. 2002 Jun 19;521(1-3):87-90.	"Huang R.-H, Xiang Y, Liu X.-Z, Zhang Y, Hu Z, Wang D.-C."	Two novel antifungal peptides distinct with a five-disulfide motif from the bark of Eucommia ulmoides Oliv.
DRAMP00979	QTCASRCPRPCNAGLCCSIYGYCGSGAAYCGAGNCRCQCRG	41	Antifungal peptide 2 (EAFP2; Plant defensin)	P83597	Belongs to the hevein-like family	Not found	Eucommia ulmoides (Hardy rubber tree)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	"EAFP2 adopts a compact global fold composed of a 3(10) helix (Cys3-Arg6), an alpha-helix (Ala27-Cys31) and a three-stranded antiparallel beta-sheet (Cys16-Ser18, Cys23-Ser25, and Cys35-Cys37) and cross-linked by five disulfide bridges. The tertiary structure of EAFP2 shows a chitin-binding domain."	1P9G resolved by X-ray.	"Function: Has antifungal activity.
PTM: Contains five disulfide bonds 3-17; 7-37; 11-23; 16-30; 35-39, and Pyrrolidone carboxylic acid at position 1."	"Fungi: Phytophthora infestans, Ascochyta lycopersici (IC50=109 ?g/ml), Verticillium dahliae, Gibberella zeae, Alternaria nicotianae, Fusarium moniliforme (IC50=18 ?g/ml), Fusarium oxysporum (IC50=94 ?g/ml) and Colletotrichum gossypii (IC50=56 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12067732##15363789##15147184	FEBS Lett. 2002 Jun 19;521(1-3):87-90.##J Struct Biol. 2004 Oct;148(1):86-97.##Biochemistry. 2004 May 25;43(20):6005-6012.	"Huang R.-H, Xiang Y, Liu X.-Z, Zhang Y, Hu Z, Wang D.-C.##Xiang Y, Huang RH, Liu XZ, Zhang Y, Wang DC.##Huang RH, Xiang Y, Tu GZ, Zhang Y, Wang DC."	Two novel antifungal peptides distinct with a five-disulfide motif from the bark of Eucommia ulmoides Oliv.##Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Eucommia ulmoides Oliver at an atomic resolution.##Solution structure of Eucommia antifungal peptide: a novel structural model distinct with a five-disulfide motif.
DRAMP00980	AQRCGDQARGAKCPNCLCCGKYGFCGSGDAYCGAGSCQSQCRGC	44	Antimicrobial peptide 1a (WAMP-1a; Plant defensin)	P85966	Belongs to the hevein-like family	Not found	Triticum kiharae (wheat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Combine helix and strand structure	Not found	2LB7 resolved by NMR.	PTM: Contains five disulfide bonds 4-19; 13-25; 16-44; 18-32; 37-41.	"Fungi: Bipolaris sorokiniana (IC50=5 ?g/ml), Botrytis cinerea (IC50=20 ?g/ml), Fusarium oxysporum (IC50=5 ?g/ml), Fusarium solani (IC50=5 ?g/ml), Fusarium verticillioides (IC50=30 ?g/ml), Neurospora crassa (IC50=10 ?g/ml);##Gram-positive bacterium: Clavibacter michiganensis (1.3cm inhibition for 2.5 ?g/50?l);##Gram-negative bacteria: Erwinia carotovora (1.1cm for 2.5 ?g/50?l), Pseudomonas syringae (0.9cm for 2.5 ?g/50?l)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	19583772##16269343	FEBS J. 2009 Aug;276(15):4266-4275.##Peptides. 2005 Nov;26(11):2064-2073.	"Odintsova TI, Vassilevski AA, Slavokhotova AA, Musolyamov AK, Finkina EI, Khadeeva NV, Rogozhin EA, Korostyleva TV, Pukhalsky VA, Grishin EV, Egorov TA.##Egorov TA, Odintsova TI, Pukhalsky VA, Grishin EV."	A novel antifungal hevein-type peptide from Triticum kiharae seeds with a unique 10-cysteine motif.##Diversity of wheat anti-microbial peptides.
DRAMP00981	AQRCGDQARGAKCPNCLCCGKYGFCGSGDAYCGAGSCQSQCRGCR	45	Antimicrobial peptide 1b (WAMP-1b; Plant defensin)	P85966	Belongs to the hevein-like family	Not found	Triticum kiharae (wheat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	PTM: Contains five disulfide bonds 4-19; 13-25; 16-44; 18-32; 37-41.	"Fungi: Bipolaris sorokiniana (IC50=5 ?g/ml), Botrytis cinerea (IC50=20 ?g/ml), Fusarium oxysporum (IC50=5 ?g/ml), F. solani (IC50=5 ?g/ml), F. verticillioides (IC50=30 ?g/ml), Neurospora crassa (IC50=10 ?g/ml);##Gram-positive bacterium: Clavibacter michiganensis (1.3cm inhibition for 2.5 ?g/50?l);##Gram-negative bacteria: Erwinia carotovora (1.1cm for 2.5 ?g/50?l), Pseudomonas syringae (0.9cm for 2.5 ?g/50?l)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	19583772##16269343	FEBS J. 2009 Aug;276(15):4266-4275.##Peptides. 2005 Nov;26(11):2064-2073.	"Odintsova TI, Vassilevski AA, Slavokhotova AA, Musolyamov AK, Finkina EI, Khadeeva NV, Rogozhin EA, Korostyleva TV, Pukhalsky VA, Grishin EV, Egorov TA.##Egorov TA, Odintsova TI, Pukhalsky VA, Grishin EV."	A novel antifungal hevein-type peptide from Triticum kiharae seeds with a unique 10-cysteine motif.##Diversity of wheat anti-microbial peptides.
DRAMP00982	AQCGAQGGGATCPGGLCCSQWGWCGSTPKYCGAGCQSNCK	40	Fa-AMP1 (Fagopyrum antimicrobial peptide 1; hevein-type; Plant defensin)	No entry found	Belongs to the hevein-like family	Not found	Fagopyrum esculentum Moench (buckwheat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Has antibacterial avtivity against Gram-positive bacteria and Gram-negative bacteria, also has antifungal activity."	"Gram-positive bacteria: Clavibacter michiganensis (IC50=14 ?g/ml), Curtobacterium accumfaciens (IC50=13 ?g/ml);##Gram-negative bacteria: Erwinia carotovora (IC50=11 ?g/ml), Agrobacterium radiobacter (IC50=24 ?g/ml), Agrobacterium rhizogenes (IC50=20 ?g/ml).##Fungi: Fusarium oxysporum (IC50=19 ?g/ml), Geotrichum candidum (IC50=36 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12951494	Biosci Biotechnol Biochem. 2003 Aug;67(8):1636-1642.	"Fujimura M, Minami Y, Watanabe K, Tadera K."	"Purification, characterization, and sequencing of a novel type of antimicrobial peptides, Fa-AMP1 and Fa-AMP2, from seeds of buckwheat (Fagopyrum esculentum Moench.)."
DRAMP00983	AQCGAQGGGATCPGGLCCSQWGWCGSTPKYCGAGCQSNCR	40	Fa-AMP2 (Fagopyrum antimicrobial peptide 2; hevein-type; Plant defensin)	No entry found	Belongs to the hevein-like family	Not found	Fagopyrum esculentum Moench (buckwheat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Has antibacterial avtivity against Gram-positive bacteria and Gram-negative bacteria, also has antifungal activity."	"Gram-positive bacteria: Clavibacter michiganensis (IC50=17 ?g/ml), Curtobacterium accumfaciens (IC50=15 ?g/ml);##Gram-negative bacteria: Erwinia carotovora (IC50=15 ?g/ml), Agrobacterium radiobacter (IC50=17 ?g/ml), Agrobacterium rhizogenes (IC50=24 ?g/ml).##Fungi: Fusarium oxysporum (IC50=29 ?g/ml), Geotrichum candidum (IC50=25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12951494	Biosci Biotechnol Biochem. 2003 Aug;67(8):1636-1642.	"Fujimura M, Minami Y, Watanabe K, Tadera K."	"Purification, characterization, and sequencing of a novel type of antimicrobial peptides, Fa-AMP1 and Fa-AMP2, from seeds of buckwheat (Fagopyrum esculentum Moench.)."
DRAMP00984	AGECVQGRCPSGMCCSQFGYCGRGPKYCGR	30	Antimicrobial peptide Ar-AMP (Ar-AMP; hevin-like peptides; Plant defensin)	Q5I2B2	Belongs to the hevein-like family	Not found	Amaranthus retroflexus (Redroot amaranth) (Redroot pigweed)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	PTM: Contains three disulfide bonds 4-15; 9-21; 14-28.	"Fungi: Botrytis cinerea, Fusarium culmorum, Helminthosporium sativum and Alternaria consortiale.##Gram-positive bacterium: Bacillus subtilis."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	16126239	Phytochemistry. 2005 Oct;66(20):2426-2431.	"Lipkin A, Anisimova V, Nikonorova A, Babakov A, Krause E, Bienert M, Grishin E, Egorov T."	An antimicrobial peptide Ar-AMP from amaranth (Amaranthus retroflexus L.) seeds.
DRAMP00985	QQCGRQASGRLCGNRLCCSQWGYCGSTASYCGAGCQSQCRS	41	Pn-AMP1 (PnAMP1; Plant defensin)	P81591	Belongs to the hevein-like family	Not found	Ipomoea nil (Japanese morning glory) (Pharbitis nil)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	"Miscellaneous: Its antimicrobial activity is strongly inhibited by divalent cations.
PTM: Contains four disulfide bonds 3-18; 12-24; 17-31; 35-39, and Pyrrolidone carboxylic acid at position 1."	"Gram-positive Bacterium: Bacillus subtilis (IC50=38 ?g/ml).##Fungi (Medium A, Medium A+): Botrytis cinerea (IC50=16, 150 ?g/ml), Colletotrichum langenarium (IC50=10, >200 ?g/ml), Sclerotinia sclerotiorum (IC50=11, >200 ?g/ml), Fusarium oxysporum (IC50=10, >200 ?g/ml), Rhizoctonia solani (IC50=26, >200 ?g/ml), Phytophthora capsici (IC50=5, 130 ?g/ml), Phytophthora parasitica (IC50=3, 90 ?g/ml), Saccharomyces cerevisiae (IC50=14, >200 ?g/ml).##NOTE! Medium A+ = Medium A supplemented with 5 mM CaCl2."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	9507071	Biochim Biophys Acta. 1998 Jan 15;1382(1):80-90.	"Koo JC, Lee SY, Chun HJ, Cheong YH, Choi JS, Kawabata S, Miyagi M, Tsunasawa S, Ha KS, Bae DW, Han CD, Lee BL, Cho MJ."	Two hevein homologs isolated from the seed of Pharbitis nil L. exhibit potent antifungal activity.
DRAMP00986	QQCGRQASGRLCGNRLCCSQWGYCGSTASYCGAGCQSQCR	40	Pn-AMP2 (PnAMP2; Plant defensin)	P81591	Belongs to the hevein-like family	Not found	Ipomoea nil (Japanese morning glory) (Pharbitis nil)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	"Miscellaneous: Its antimicrobial activity is strongly inhibited by divalent cations.
PTM: Contains four disulfide bonds 3-18; 12-24; 17-31; 35-39, and Pyrrolidone carboxylic acid at position 1."	"Gram-positive bacterium: Bacillus subtilis (IC50=20 ?g/ml).##Fungi (Medium A, Medium A+): Botrytis cinerea (IC50=2, 95 ?g/ml), Colletotrichum langenarium (IC50=4, ND ?g/ml), Sclerotinia sclerotiorum (IC50=3, >200 ?g/ml), Fusarium oxysporum (IC50=2.5, >200 ?g/ml), Rhizoctonia solani (IC50=75, >200 ?g/ml), Phytophthora capsici (IC50=0.6, 150 ?g/ml), Phytophthora parasitica (IC50=2, >200 ?g/ml), Pythium spp. (IC50=2.5, ND ?g/ml), Saccharomyces cerevisiae (IC50=8, >200 ?g/ml).##NOTE! Medium A+ = Medium A supplemented with 5 mM CaCl2."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	9507071	Biochim Biophys Acta. 1998 Jan 15;1382(1):80-90.	"Koo JC, Lee SY, Chun HJ, Cheong YH, Choi JS, Kawabata S, Miyagi M, Tsunasawa S, Ha KS, Bae DW, Han CD, Lee BL, Cho MJ."	Two hevein homologs isolated from the seed of Pharbitis nil L. exhibit potent antifungal activity.
DRAMP00987	QQCGRQAGNRRCANNLCCSQYGYCGRTNEYCCTSQGCQSQCRRCG	45	Ee-CBPb (Hevein-like antimicrobial peptide; Plants)	No entry found	Belongs to the hevein-like family	Not found	Euonymus europaeus (European spindle tree)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Not found	Not found	Not found	None	"Function: Ee-CBPb possesses a very strong antifungal activity. Besides fungi, Ee-CBP1 also inhibits the growth of Gram-positive bacteria but not that of Gram-negative bacteria and yeasts.
PTM: Contains five disulfide bonds."	"Fungi: Alternaria brassicicola (IC50=3 ?g/ml), Botrytis cinerea (IC50=1 ?g/ml), Fusarium culmorum (IC50=3 ?g/ml), Fusarium oxysporum f.sp.cubense (IC50=15 ?g/ml), Fusarium oxysporum f.sp. Matthiolae (IC50=5 ?g/ml), Mycosphaerella eumusae (IC50=6 ?g/ml), Neurospora crassa (IC50=2 ?g/ml), Phoma exigua (IC50=33 ?g/ml), Phytophthora cryptogea (IC50=25 ?g/ml), Pythium ultimum (IC50=33 ?g/ml), Rhizoctonia solani (IC50=25 ?g/ml).##Gram-positive bacteria: Bacillus megaterium (IC50=2 ?g/ml), Sarcina lutea (IC50=7 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	15048569##12387889	Planta. 2004 Jun;219(2):221-232.##FEBS Lett. 2002 Oct 23;530(1-3):181-185.	"Van den Bergh KP, Roug? P, Proost P, Coosemans J, Krouglova T, Engelborghs Y, Peumans WJ, Van Damme EJ.##Van den Bergh KP, Proost P, Van Damme J, Coosemans J, Van Damme EJ, Peumans WJ."	Synergistic antifungal activity of two chitin-binding proteins from spindle tree (Euonymus europaeus L.).##Five disulfide bridges stabilize a hevein-type antimicrobial peptide from the bark of spindle tree (Euonymus europaeus L.).
DRAMP00988	QQCGRQAGNRRCPNNLCCSQFGYCGRTNEYCCTGFGCQSNCRRCG	45	Ee-CBPl (Hevein-like antimicrobial peptide; Plants)	No entry found	Belongs to the hevein-like family	Not found	Euonymus europaeus (European spindle tree)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	"Function: Ee-CBP1 possesses a very strong antifungal activity. 
PTM: Contains Disulfide bond."	"Fungi: Alternaria brassicicola (IC50=0.6 ?M), Botrytis cinerea (IC50=0.2 ?M), Fusarium culmorum (IC50=0.6 ?M), Fusarium oxysporum f. sp. cubense (IC50=3 ?M), Fusarium oxysporum f. sp. matthiolae (IC50=1 ?M), Mycosphaerella eumusae (IC50=1.2 ?M), Neurospora crassa (IC50=0.4 ?M), Phoma exigua (IC50=6.6 ?M),Phytophthora cryptogea (IC50=5 ?M), Pythium ultimum (IC50=6.6 ?M), Rhizoctonia solani (IC50=5 ?M), Trichoderma hamatum (IC50=20 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	15048569	Planta. 2004 Jun;219(2):221-232.	"Van den Bergh KP, Roug? P, Proost P, Coosemans J, Krouglova T, Engelborghs Y, Peumans WJ, Van Damme EJ."	Synergistic antifungal activity of two chitin-binding proteins from spindle tree (Euonymus europaeus L.).
DRAMP00989	EQCGRQAGGKLCPNNLCCSQWGWCGSTDEYCSPDHNCQSNCKD	43	Hevein (Hev b 6; Plants)	P02877	Belongs to the hevein-like family	HEV1	Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	The first high-resolution solution-state structure of a member of the toxin-agglutinin folding motif with the WGA disulfide linkage is presented.	"1HEV resolved by NMR.##1Q9B, 1WKX resolved by X-ray."	"Function: N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin. Can inhibit fungal growth.
PTM: Proteolytically processed to yield the two chains of the mature protein, and it Contains four disulfide bonds 3-18; 12-24; 17-31; 37-41.
Allergenic properties: Causes an allergic reaction in human."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	2217194##8431421	Proc Natl Acad Sci U S A. 1990 Oct;87(19):7633-7637.##Biochemistry. 1993 Feb 16;32(6):1407-1422.	"Broekaert I, Lee HI, Kush A, Chua NH, Raikhel N.##Andersen NH, Cao B, Rodr¨ªguez-Romero A, Arreguin B."	Wound-induced accumulation of mRNA containing a hevein sequence in laticifers of rubber tree (Hevea brasiliensis).##Hevein: NMR assignment and assessment of solution-state folding for the agglutinin-toxin motif.
DRAMP00990	KICERASGTWKGICIHSNDCNNQCVKWENAGSGSCHYQFPNYMCFCYFDC	50	Sm-AMP-D1 (Plant defensin)	No entry found	Not found	Not found	Stellaria media L (Common chickweed seeds)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Function: Sm-AMP-D defensins displays strong antifungal activity against important plant pathogens being active at very low concentrations (IC50=1 M).	"Fungi: Fusarium oxysporum 16/10 (IC50=0.5 ?M), Botrytis cinerea SGR-1 (IC50=0.35 ?M), Bipolaris sorokiniana 6/10 (IC50=0.52 ?M), Fusarium graminearum VKM F-1668 (IC50=0.52 ?M), Fusarium avenaceum VKM F-2303 (IC50=1 ?M), Phoma betae VKM F-2532 (IC50=0.52 ?M), Pythium debaryanum VKMF-1505 (IC50=1 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21056078	Biochimie. 2011 Mar;93(3):450-456.	"Slavokhotova AA, Odintsova TI, Rogozhin EA, Musolyamov AK, Andreev YA, Grishin EV, Egorov TA."	"Isolation, molecular cloning and antimicrobial activity of novel defensins from common chickweed (Stellaria media L.) seeds."
DRAMP00991	EQCGRQAGGKLCPNNLCCSQYGWCGSSDDYCSPSKNCQSNCKGGG	45	Pseudo-hevein (Minor hevein; hevein-like peptides; Plants)	P80359	Not found	Not found	Hevea brasiliensis (Para rubber tree) 	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin. Can inhibit fungal growth.
PTM: Problely Contains four disulfide bonds 3-18; 12-24; 17-31; 37-41."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	7947977	Biochim Biophys Acta. 1994 Nov 16;1209(1):144-148.	"Soedjanaatmadja UM, Hofsteenge J, Jeronimus-Stratingh CM, Bruins AP, Beintema JJ."	Demonstration by mass spectrometry that pseudo-hevein and hevein have ragged C-terminal sequences.
DRAMP00992	KICERASGTWKGICIHSNDCNNQCVKWENAGSGSCHYQFPNYMCFCYFNC	50	Sm-AMP-D2 (Plant defensin)	No entry found	Not found	Not found	Stellaria media L (Common chickweed seeds)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Function: Sm-AMP-D defensins displays strong antifungal activity against important plant pathogens being active at very low concentrations (IC50=1 M).	"Fungi: Fusarium oxysporum 16/10 (IC50=0.5 ?M), Botrytis cinerea SGR-1 (IC50=0.35 ?M), Bipolaris sorokiniana 6/10 (IC50=0.52 ?M), Fusarium graminearum VKM F-1668 (IC50=0.52 ?M), Fusarium avenaceum VKM F-2303 (IC50=1 ?M), Phoma betae VKM F-2532 (IC50=0.52 ?M), Pythium debaryanum VKMF-1505 (IC50=1 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21056078	Biochimie. 2011 Mar;93(3):450-456.	"Slavokhotova AA, Odintsova TI, Rogozhin EA, Musolyamov AK, Andreev YA, Grishin EV, Egorov TA."	"Isolation, molecular cloning and antimicrobial activity of novel defensins from common chickweed (Stellaria media L.) seeds."
DRAMP00993	QAGGQTCPGGICCSQWGYCGTTADYCSPNNNCQSNCWASG	40	WjAMP-1 (C-terminal domain of hevein; Plant defensin)	No entry found	Not found	WjAMP-1	Wasabia japonica L. (Wasabi plant) (Wasabia japonica) 	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: WjAMP-1 showed antimicrobial activity against both fungi and bacteria.	"Gram-negative bacteria: Escherichia coli (IC50=27.5 ?g/ml), Pseudomonas cichorii (IC50=13.8 ?g/ml), Pseudomonas glumae (IC50=20 ?g/ml), Pseudomonas plantarii (IC50=22.5 ?g/ml), Agrobacterium tumefaciens (IC50=12.5 ?g/ml).##Fungi: Alternaria alternata (IC50=5.8 ?g/ml), Botrytis cinerea (IC50=15 ?g/ml), Fusarium solani (IC50=8.4 ?g/ml), Magnaporte grisea (IC50=80 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12668776	Plant Cell Physiol. 2003 Mar;44(3):296-303.	"Kiba A, Saitoh H, Nishihara M, Omiya K, Yamamura S."	C-terminal domain of a hevein-like protein from Wasabia japonica has potent antimicrobial activity.
DRAMP00994	QWGRRCCGWGPGRRYCVRWC	20	IB-AMP1 (IBAMP1; Basic peptide AMP1; Plants)	O24006	Not found	AMP	Impatiens balsamina (Balsam)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	"Developmental stage: Highly expressed in dry mature seed and by the stages 2-5 of developing seed. The peptide IB-AMP1 is also detected at early stages of germination (24 hours and 48 hours postgermination).
PTM: Contains two disulfide bonds C6-C16; C7-C2"	"Gram-positive bacteria: Bacillus subtilis (IC50=10 ?g/ml), Micrococcus luteus (IC50=10 ?g/ml), Staphylococcus aureus (IC50=30 ?g/ml), Streptococcus faecalis (IC50=6 ?g/ml).##Fungi: Alternaria longipes (IC50=3 ?g/ml), Botrytis cinerea (IC50=12 ?g/ml), Cladosporium sphaerospermum (IC50=1 ?g/ml), Fusarium culmorum (IC50=1 ?g/ml), Penicillium digitatum (IC50=3 ?g/ml), Trichoderma viride (IC50=6 ?g/ml), Verticillium alboatrum (IC50=3 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9305910##9454588	J Biol Chem. 1997 Sep 26;272(39):24480-24487.##Biochemistry. 1998 Jan 27;37(4):983-990.	"Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF.##Patel SU, Osborn R, Rees S, Thornton JM."	A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein.##Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1).
DRAMP00995	QYGRRCCNWGPGRRYCKRWC	20	IB-AMP2 (IBAMP2; Basic peptide AMP2; Plants)	O24006	Not found	Not found	Impatiens balsamina (Balsam)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Developmental stage: Highly expressed in dry mature seed and by the stages 2-5 of developing seed.
PTM: Contains two disulfide bonds C6-C16; C7-C20 and Pyrrolidone carboxylic acid at position 1 (Probable)."	"Fungi: Alternaria longipes (IC50=12 ?g/ml), Botrytis cinerea (IC50=25 ?g/ml), Cladosporium sphaerospermum (IC50=6 ?g/ml), Fusarium culmorum (IC50=6 ?g/ml), Penicillium digitatum (IC50=6 ?g/ml), Trichoderma viride (IC50=12 ?g/ml), Verticillium alboatrum (IC50=12 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9305910	J Biol Chem. 1997 Sep 26;272(39):24480-24487.	"Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF."	A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein.
DRAMP00996	QYRHRCCAWGPGRKYCKRWC	20	IB-AMP3 (IBAMP3; Basic peptide AMP3; Plants)	O24006	Not found	Not found	Impatiens balsamina (Balsam)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Developmental stage: Highly expressed in dry mature seed and by the stages 2-5 of developing seed.
PTM: Contains two disulfide bonds C6-C16; C7-C20 and Pyrrolidone carboxylic acid at position 1 (Probable)."	"Fungi: Alternaria longipes (IC50=6 ?g/ml), Botrytis cinerea (IC50=6 ?g/ml), Cladosporium sphaerospermum (IC50=3 ?g/ml), Fusarium culmorum (IC50=6 ?g/ml), Penicillium digitatum (IC50=3 ?g/ml), Trichoderma viride (IC50=12 ?g/ml), Verticillium alboatrum (IC50=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9305910	J Biol Chem. 1997 Sep 26;272(39):24480-24487.	"Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF."	A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein.
DRAMP00997	QWGRRCCGWGPGRRYCRRWC	20	IB-AMP4 (IBAMP4; Basic peptide AMP4; Plants)	O24006	Not found	Not found	Impatiens balsamina (Balsam)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	Developmental stage: Highly expressed in dry mature seed and by the stages 2-5 of developing seed. PTM: Contains two disulfide bonds C6-C16; C7-C20 and Pyrrolidone carboxylic acid at position 1 (Probable). Note: Peptide IB-AMP4 has a higher antifungal act	"Gram-positive bacteria: Bacillus subtilis (IC50=5 ?g/ml), Micrococcus luteus (IC50=5 ?g/ml), Staphylococcus aureus (IC50=20 ?g/ml), Streptococcus faecalis (IC50=5 ?g/ml);##Gram-negative bacteria: Xanthomonas campestris (IC50=6 ?g/ml), Xanthomonas oryzae (IC50=15 ?g/ml).##Fungi: Alternaria longipes (IC50=3 ?g/ml), Botrytis cinerea (IC50=6 ?g/ml), Cladosporium sphaerospermum (IC50=1 ?g/ml), Fusarium culmorum (IC50=1 ?g/ml), Penicillium digitatum (IC50=3 ?g/ml), Trichoderma viride (IC50=6 ?g/ml), Verticillium alboatrum (IC50=6 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9305910##9454588	J Biol Chem. 1997 Sep 26;272(39):24480-24487.##Biochemistry. 1998 Jan 27;37(4):983-990.	"Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF.##Patel SU, Osborn R, Rees S, Thornton JM."	A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein.##Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1).
DRAMP00998	RSGRGECRRQCLRRHEGQPWETQECMRRCRRRG	33	Antimicrobial peptide MBP-1 (Maize Basic Peptide 1; Plant defensin)	P28794	Not found	Not found	Zea mays (Maize)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Inhibitor of both bacterial and fungal growth in vitro.	"Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Corynebacterium nebraskense ssp.##Fungi: Fusarium graminearum, Fusarium moniliforme, Aspergillus flavus, Alonina longipes, Sclerotinia sclerotiorum, Sclerotinia trifoliorum. "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1527010	J. Biol. Chem. 1992; 267:18814-18820	"Duvick JP, Rood T, Rao AG, Marshak DR.1992"	Purification and characterization of a novel antimicrobial peptide from maize (Zea mays L.) kernels.
DRAMP00999	GFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY	40	Plectasin (fungal defensin)	Q53I06	Not found	DEF	Pseudoplectania nigrella (Ebony cup)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Combine helix and strand structure	Not found	1ZFU resolved by NMR.	"Function: Recombinant peptide is especially active against Streptococcus pneumoniae, including strains resistant to conventional antibiotics. Plectasin showes extremely low toxicity in mice, and cured them of experimental peritonitis and pneumonia caused by S. pneumoniae as efficaciously as vancomycin and penicillin."	Gram-positive bacterium: Streptococcus pneumoniae.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid II 	16222292	Nature. 2005 Oct 13;437(7061):975-780.	"Mygind PH, Fischer RL, Schnorr KM, Hansen MT, S?nksen CP, Ludvigsen S, Ravent?s D, Buskov S, Christensen B, De Maria L, Taboureau O, Yaver D, Elvig-J?rgensen SG, S?rensen MV, Christensen BE, Kjaerulff S, Frimodt-Moller N, Lehrer RI, Zasloff M, Kristensen "	Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus.
DRAMP01000	YQCGQGG	7	Ascalin (Plants)	P84071	Not found	Not found	 Allium cepa var. aggregatum (shallot)	"Antimicrobial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	"Function: Has antifungal activity against Botrytis cinerea. Inhibits HIV-1 reverse transcriptase.
Miscellaneous: Inhibits HIV-1 reverse transcriptase with an IC50 of 10 ?M."	"Botrytis cinerea, HIV-1 reverse transcriptase (IC50=10 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12126728	Peptides. 2002 Jun;23(6):1025-1029.	"Wang HX, Ng TB."	"Ascalin, a new anti-fungal peptide with human immunodeficiency virus type 1 reverse transcriptase-inhibiting activity from shallot bulbs."
DRAMP01001	GVGYKVVVTTTAAADDDDVV	20	Arietin (Plants)	P83988	Not found	Not found	Cicer arietinum (chickpea)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity. Inhibits cell-free translation in rabbit reticulocyte lysate system. Does not have mitogenic and anti-HIV-1 reverse transcriptase activities.	"Fungi: Botrytis cinerea, Fusarium oxysporum, Mycosphaerella arachidicola."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12084511	Peptides. 2002 May;23(5):817-822.	"Ye XY, Ng TB, Rao PF."	"Cicerin and arietin, novel chickpea peptides with different antifungal potencies."
DRAMP01002	RDWERREFERRQNELRREQEQRREELL	27	Alpha-benincasin (Plants)	P83960	Not found	Not found	Benincasa hispida 	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has weak antifungal activity toward C. comatus and P. piricola but not toward M. arachidicola. Inhibits cell-free translation in rabbit reticulocyte lysate system.
Miscellaneous: IC50 of 20 pM in rabbit reticulocyte."	"Fungi: Coprinus comatus, Pseudocercospora piricola."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12576080	Peptides. 2003 Jan;24(1):11-16.	"Ng TB, Parkash A, Tso WW."	"Purification and characterization of alpha- and beta-benincasins, arginine/glutamate-rich peptides with translation-inhibiting activity from wax gourd seeds."
DRAMP01003	KTCENLADDY	10	Gymnin (Plants)	P84200	Not found	Not found	Gymnocladus chinensis 	"Antimicrobial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	Function: Exerts antifungal activity. Has weak mitogenic activity against murine splenocytes. Displays antiproliferative activity on a human hepatoma cell line and mouse leukemia cell lines. Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase.	"Fungi: Fusarium oxysporum (IC50=2 ?M), Mycosphaerella arachidicola (IC50=10 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14499273	Peptides. 2003 Jul;24(7):963-968.	"Wong JH, Ng TB."	"Gymnin, a potent defensin-like antifungal peptide from the Yunnan bean (Gymnocladus chinensis Baill)."
DRAMP01005	VKSTGRADDDLAVKTKYLPP	20	Cicerarin (Plant defensin)	P83986	Not found	Not found	Cicer arietinum (chickpea)	"Antimicrobial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	Function: Has antifungal activity. Also inhibits HIV-1 reverse transcriptase.	"Fungi: Botrytis cinerea (IC50=20.6 ?M), Mycosphaerella arachidicola (IC50=15.3 ?M), Pseudocercospora piricola (IC50=8.2 ?M).##Virus: HIV-1 RT (IC50=87.5 ?M)"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12895650	Peptides. 2003 May;24(5):659-663.	"Chu KT, Liu KH, Ng TB."	"Cicerarin, a novel antifungal peptide from the green chickpea."
DRAMP01006	ARCENFADSYRQPPISSSQT	20	Cicerin (Plant defensin)	P83987	Not found	Not found	Cicer arietinum (chickpea)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity. Inhibits cell-free translation in rabbit reticulocyte lysate system.	"Fungi: Mycosphaerella arachidicola, Fusarium oxysporum, Botrytis cinerea (IC50=12 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12084511	Peptides. 2003 May;24(5):665-669.	"Cai YD, Liu XJ, Li YX, Xu XB, Chou KC."	"Cicerin and arietin, novel chickpea peptides with different antifungal potencies."
DRAMP01007	MTCGQVQGNLAQCIGFLQKGGVVPPSCCTGVKNILNSSRTTADRRAVCSCLKAAAGAVRGINPNNAEALPGKCGVNIPYKISTSTNCNSIN	91	Non-specific lipid transfer peptide (LTP 1; nsLTP; Plants)	P83434	Not found	Not found	Vigna radiata var. radiata (Mung bean) (Phaseolus aureus)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Alpha helix (4 helices; 46 residues)	The global fold of mung bean nsLTP1 is similar to those of the monocotyledonous nsLTP1 structures and consists of four alpha-helices stabilized by four disulfide bonds.	1SIY resolved by NMR.	"Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
PTM: Contains four disulfide bonds 3-50; 13-27; 28-73; 48-87."	"Fungi: Fusarium solani, Fusarium oxysporum, Pythium aphanidermatum, Sclerotium rolfsii.##Gram-positive Bacterium: Staphylococcus aureus."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	15350690##15823028	Peptides. 2004 Aug;25(8):1235-1242.##Biochemistry. 2005 Apr 19;44(15):5703-5712.	"Wang SY, Wu JH, Ng TB, Ye XY, Rao PF.##Lin KF, Liu YN, Hsu ST, Samuel D, Cheng CS, Bonvin AM, Lyu PC."	A non-specific lipid transfer protein with antifungal and antibacterial activities from the mung bean.## Characterization and structural analyses of nonspecific lipid transfer protein 1 from mung bean.
DRAMP01008	SNDIYFNFQR	10	Antifungal lectin PVAP (Plant defensin)	P84869	Not found	Not found	Phaseolus vulgaris (Kidney bean)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has hemagglutinating activity towards rabbit erythrocytes. Has antiproliferative activity towards L1210 tumor cell line with an IC50 of 3.6 ?M. 
Miscellaneous: Antifungal, antiproliferative and hemagglutinating activity is abolished by incubatio"	Fungi: Mycophaerella arachidicola (IC50=9.8 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16026901	Peptides. 2005 Dec;26(12):2397-2403.	"Xia L, Ng T.B."	An antifungal protein from flageolet beans
DRAMP01009	DDFLCAGGCL	10	Alliumin (Plants)	P84796	Not found	Not found	Allium sativum (Garlic)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity against M.arachidicola with an IC50 of 1.3 ?M. Has antibacterial activity against the Gram-negative bacteria P. fluorescens. Has antiproliferative activity towards L1210 leukemia cells with an IC50 of 8.33 ?M.	Fungi: Mycosphaerella arachidicola (IC50=1.3 ?M).##Gram-negative bacterium: Pseudomonas fluorescens.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15629528	Peptides. 2005 Feb;26(2):177-183.	"Xia L, Ng TB."	"Isolation of alliumin, a novel protein with antimicrobial and antiproliferative activities from multiple-cloved garlic bulbs."
DRAMP01010	KTCENLADTFRGPCFATSNC	20	Lunatusin (Plants)	No entry found	Not found	Not found	Phaseolus lunatus L.(Chinese lima bean)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral, Antifungal"	Not found	Not found	Not found	None	Function: It also inhibited proliferation in the breast cancer cell line MCF-7. Lunatusin reduced the activity of HIV-1 reverse transcriptase and it also inhibited translation in a cell-free rabbit reticulocyte lysate system. Its anti-fungal activity was 	"Fungi: Fusarium oxysporum, Mycosphaerella arachidicola and Botrytis cinerea.##Gram-positive bacteria: Bacillus megaterium, Bacillus subtilis;##Gram-negative bacteria: Proteus vulgaris, Mycobacterium phlei."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16269344	Peptides. 2005 Nov;26(11):2086-2092.	"Wong JH, Ng TB."	"Lunatusin, a trypsin-stable antimicrobial peptide from lima beans (Phaseolus lunatus L.)."
DRAMP01011	KTCENLADTFRGPCFATSNCDDHCKNKEHLLSGRCRDDFRCWCTRNC	47	White cloud bean defensin (Plant defensin)	No entry found	Not found	Not found	Phaseolus vulgaris cv. white cloud beans	"Antimicrobial, Antibacterial, Antifungal"	Not found	Bridge	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16687191	Peptides. 2006 Sep;27(9):2075-2081.	"Wong JH, Zhang XQ, Wang HX, Ng TB."	A mitogenic defensin from white cloud beans (Phaseolus vulgaris).
DRAMP01013	KTCENLADTYKGPCFTTGSCD	21	PvD1 (P. vulgaris defensin 1; Plants)	F8QXP9	Not found	Not found	Phaseolus vulgaris (Seeds)	"Antimicrobial, Antifungal"	Predicted	Bridge	Not found	None	"Its activity involves membrane permeabilization, inhibition of medium acifification, and induction of ROS in fungi cells (Curr Microbiol. 2010 Dec 19. 62: 1209-1217). "	"Fungi: Candida albicans, C. parapsilosis, Candida tropicalis, Candida guilliermondii, K. marxiannus, Saccharomyces cerevisiae, Fusarium oxysporum, F. solani, F. lateritium and R. solani."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18786582	Peptides. 2008 Dec;29(12):2090-2100.	"Games PD, Dos Santos IS, Mello EO, Diz MS, Carvalho AO, de Souza-Filho GA, Da Cunha M, Vasconcelos IM, Ferreira Bdos S, Gomes VM."	"Isolation, characterization and cloning of a cDNA encoding a new antifungal defensin from Phaseolus vulgaris L. seeds."
DRAMP01014	RTCMIKKEGWGKCLIDTTCAHSCKNRGYIGGNCKGMTRTCYCLVNC	46	VrD1 (V.radiata defensin 1; Plants)	No entry found	Not found	Not found	Vigna radiata	"Antimicrobial, Antifungal"	Not found	Combine helix and strand structure	Not found	1TI5 resolved by NMR.	Comment: No comments found on DRAMP database	"Fungi: Fusarium oxysporum, Pyricularia oryza, Rhizoctonia solani, Trichophyton rubrum, bruchid larva."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15080630	J Agric Food Chem 2004; 52: 2256-2261.	Chen JJ et al Chen CS.	Cloning and functional expression of a mungbean defensin VrD1 in Pichia pastoris.
DRAMP01015	RTCMKKEGWGKCLIDTTCAHSCKNRGYIGGNCKGMTRTCYCLVNC	45	VaD1 (Plant defensin)	No entry found	Not found	Not found	Vigna angularis Kao Hsiung No.6 (Seeds)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Fusarium oxysporum, Fusarium oxysporum f. sp. Pisi.##Gram-positive bacterium: Staphylococcus epidermidis;##Gram-negative bacterium: Salmonella typhimurium."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15713009	J Agric Food Chem 2005; 53: 982-988.	"Chen G.-H. et al. Chen, C.-S."	Cloning and characterization of a plant defensin VaD1 from Azuki Bean.
DRAMP01019	KTCENLANTYRGPCFTTGSCDDHCKNKEHLRSGRCRDDFRCWCTRNC	47	VrD2 (Vigna radiata defensin 2; plant defensin)	No entry found	Not found	Not found	Vigna radiata	"Antimicrobial, Antibacterial, Antifungal"	Not found	Combine helix and strand structure	Not found	2GL1 resolved by NMR.	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Proteins 2007; 68: 530-540.	"Lin KF, Lee TR, Tsai PH, Hsu MP, Chen CS, Lyu PC."	NMR solution structure of Vigna radiata Defensin 2 (VrD2).
DRAMP01022	KGAPCAKKPCCGPLGHYKVDCSTIPDYPCCSKYGFCGSGPQYCG	44	Cy-AMP1 (Plant defensin)	No entry found	Not found	Not found	Cycas revoluta (cycad seeds)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Cy-AMP1 has antimicrobial activity against various plant-pathogenic fungi and bacteria.	"Gram-positive bacteria: Clavibacterium michiganensis (IC50=7.3 ?g/ml), Curtobacterium ???accumfaciens (IC50=8.9 ?g/ml);##Gram-negative bacteria: Agrobacterium radiobacter (IC50=8.3 ?g/ml), Agrobacterium rhizogenes (IC50=8.5 ?g/ml), Erwinia carobora (IC50=8.0 ?g/ml).##Fungi: Fusarium oxysporum (IC50=6.0 ?g/ml), Geotrichum candidum (IC50=7.4 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	18778743	Peptides. 2008 Dec;29(12):2110-2117.	"Yokoyama S, Kato K, Koba A, Minami Y, Watanabe K, Yagi F."	"Purification, characterization, and sequencing of antimicrobial peptides, Cy-AMP1, Cy-AMP2, and Cy-AMP3, from the Cycad (Cycas revoluta) seeds."
DRAMP01023	KGGPCAKKPCCGPLGHYKVDCSTIPDYPCCSKYGFCGSGPQYCG	44	Cy-AMP2 (Plant defensin)	No entry found	Not found	Not found	Cycas revoluta (cycad seeds)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Cy-AMP2 has antimicrobial activity against various plant-pathogenic fungi and bacteria.	"Gram-positive bacteria: Clavibacterium michiganensis (IC50=7.6 ?g/ml), Curtobacterium ???accumfaciens (IC50=8.3 ?g/ml);##Gram-negative bacteria: Agrobacterium radiobacter (IC50=7.8 ?g/ml), Agrobacterium rhizogenes (IC50=8.2 ?g/ml), Erwinia carobora (IC50=8.1 ?g/ml).##Fungi: Fusarium oxysporum (IC50=7.1 ?g/ml), Geotrichum candidum (IC50=7.0 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	18778743	Peptides. 2008 Dec;29(12):2110-2117.	"Yokoyama S, Kato K, Koba A, Minami Y, Watanabe K, Yagi F."	"Purification, characterization, and sequencing of antimicrobial peptides, Cy-AMP1, Cy-AMP2, and Cy-AMP3, from the Cycad (Cycas revoluta) seeds."
DRAMP01024	AVTCNTVVSSLAPCVPFFAGSAAQPTAACCNGVRSLNSAARTTPDRRTACNCIKSSASSIGLNYNKAAKLPSRCTVNVTVPISPSVNCAT	90	Cy-AMP3 (Plant defensin)	No entry found	Not found	Not found	Cycas revoluta (cycad seeds)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Cy-AMP3 has weak antimicrobial activity against various plant-pathogenic fungi and bacteria.	"Gram-positive bacteria: Clavibacterium michiganensis (IC50=235 ?g/ml), Curtobacterium ???accumfaciens (IC50=195 ?g/ml);##Gram-negative bacteria: Agrobacterium radiobacter (IC50=260 ?g/ml), Agrobacterium rhizogenes (IC50=235 ?g/ml), Erwinia carobora (IC50=230 ?g/ml).##Fungi: Fusarium oxysporum (IC50=250 ?g/ml), Geotrichum candidum (IC50=200 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	18778743	Peptides. 2008 Dec;29(12):2110-2117.	"Yokoyama S, Kato K, Koba A, Minami Y, Watanabe K, Yagi F."	"Purification, characterization, and sequencing of antimicrobial peptides, Cy-AMP1, Cy-AMP2, and Cy-AMP3, from the Cycad (Cycas revoluta) seeds."
DRAMP01025	ESEFDRQEYEECKRQCMQLETSGQMRRCVSQCDKRFEEDIDWSKYDNQD	49	Vicilin-like Antimicrobial peptide 2a (MiAMP2a; Plant defensin)	Q9SPL4	Belongs to the vicilin-like family	AMP2-2	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml).##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01026	DPQTDCQQCQRRCRQQESGPRQQQYCQRRCKEICEEEEEYN	41	Vicilin-like Antimicrobial peptide 2b (MiAMP2b; Plant defensin)	Q9SPL4	Belongs to the vicilin-like family	AMP2-2	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2b has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01027	RQRDPQQQYEQCQKHCQRRETEPRHMQTCQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEEDN	68	MiAMP2c (Gln- and Glu-rich; Plant defensin)	No entry found	Belongs to the vicilin-like family	Not found	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antifungal"	Not found	Rich	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01028	RQRDPQQQYEQCQERCQRHETEPRHMQTCQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEED	67	Vicilin-like Antimicrobial peptide 2c-3 (MiAMP2c-3; Plant defensin)	Q9SPL4	Belongs to the vicilin-like family	AMP2-2	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01029	RQRDPQQQYEQCQERCQRHETEPRHMQTCQQRCERRYEKEKRKQQKR	47	Vicilin-like Antimicrobial peptide 2c-2 (MiAMP2c-2; Plant defensin)	Q9SPL4	Belongs to the vicilin-like family	AMP2-2	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01030	RQRDPQQQYEQCQERCQRHETEPRHMQTCQQRCERRYEKEKRKQQ	45	Vicilin-like Antimicrobial peptide 2c-1 (MiAMP2c-1; Plant defensin)	Q9SPL4	Belongs to the vicilin-like family	AMP2-2	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01031	KRDPQQREYEDCRRRCEQQEPRQQYQCQRRCREQQ	35	Vicilin-like Antimicrobial peptide 2d (MiAMP2d; Plant defensin)fens	Q9SPL4	Belongs to the vicilin-like family	AMP2-2	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2d has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01032	DPQTECQQCQRRCRQQESDPRQQQYCQRRCKEICEEEEEYN	41	Vicilin-like Antimicrobial peptide 2b (MiAMP2b; Plant defensin)	Q9SPL3	Belongs to the vicilin-like family	AMP2-3	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Antimicrobial peptides 2b has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01033	RQRDPQQQYEQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEGD	67	Vicilin-like Antimicrobial peptide 2c-3 (MiAMP2c-3; Plant defensin)	Q9SPL3	Belongs to the vicilin-like family	AMP2-3	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01034	RQRDPQQQYEQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQKR	47	Vicilin-like Antimicrobial peptide 2c-2 (MiAMP2c-2; Plant defensin)	Q9SPL3	Belongs to the vicilin-like family	AMP2-3	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01035	RQRDPQQQYEQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQ	45	Vicilin-like Antimicrobial peptide 2c-1 (MiAMP2c-1; Plant defensin)	Q9SPL3	Belongs to the vicilin-like family	AMP2-3	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01036	KRDPQQREYEDCRRHCEQQEPRLQYQCQRRCQEQQ	35	Vicilin-like Antimicrobial peptide 2d (MiAMP2d; Plant defensin)	Q9SPL3	Belongs to the vicilin-like family	AMP2-3	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Antimicrobial peptides 2d has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01037	DPQTECQQCQRRCRQQESGPRQQQYCQRRCKEICEEEEEYN	41	Vicilin-like Antimicrobial peptide 2b (MiAMP2b; Plant defensin)	Q9SPL5	Belongs to the vicilin-like family	AMP2-1	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2b has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01038	RQRDPQQQYEQCQKHCQRRETEPRHMQTCQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEED	67	Vicilin-like Antimicrobial peptide 2c-3 (MiAMP2c-3; Plant defensin)	Q9SPL5	Belongs to the vicilin-like family	AMP2-1	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01039	RQRDPQQQYEQCQKHCQRRETEPRHMQTCQQRCERRYEKEKRKQQKR	47	Vicilin-like Antimicrobial peptide 2c-2 (MiAMP2c-2; Plant defensin)	Q9SPL5	Belongs to the vicilin-like family	AMP2-1	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01040	RQRDPQQQYEQCQKHCQRRETEPRHMQTCQQRCERRYEKEKRKQQ	45	Vicilin-like Antimicrobial peptide 2c-1 (MiAMP2c-1; Plant defensin)	Q9SPL5	Belongs to the vicilin-like family	AMP2-1	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01041	KRDPQQREYEDCRRRCEQQEPRQQHQCQLRCREQQ	35	Vicilin-like Antimicrobial peptide 2d (MiAMP2d; Plant defensin)	Q9SPL5	Belongs to the vicilin-like family	AMP2-1	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antimicrobial peptides 2d has antibacterial and antifungal activity against a range of species (By similarity).	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml)##NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP01043	QICKAPSQTFPGLCFMDSSCRKYCIKEKFTGGHCSKLQRKCLCTKPC	47	TPP3 (Plant defensin)	No entry found	Not found	Not found	Lycopersicon esculentum	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7647301	Plant Mol Biol 1995; 28:691-711.	"Milligan SB, Gasser CS."	Nature and regulation of pistil-expressed genes in tomato.
DRAMP01044	KTCENLVDTYRGPCFTTGSCDDHCKNKEHLLSGRCRDDVRCWCTRNC	47	Defensin-like protein (Clone PSAS10; Plant defensin)	P18646	Not found	Not found	Vigna unguiculata (cowpea seeds)	"Antimicrobial, Antifungal"	Homology	Bridge	Not found	None	This protein is required for germination.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2103443	Plant Mol Biol. 1990 Jul;15(1):59-64.	"Ishibashi N, Yamauchi D, Minamikawa T."	Stored mRNA in cotyledons of Vigna unguiculata seeds: nucleotide sequence of cloned cDNA for a stored mRNA and induction of its synthesis by precocious germination.
DRAMP01045	ITCGLVASKLAPCIGYLQGAPGPSAACCGGIKSLNSAAASPADRKTACTCLKSAATSMKGINYGKAASLPRQCGVSIPYAISPNTNCNAIH	91	IWF2 (Bv-LTP2; Plant defensin)	No entry found	Not found	IWF1	Beta vulgaris (Sugar beet)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Also has fungicide activity.	Fungi: Cercospora beticola.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	8790287	Plant Mol Biol. 1996 Jun;31(3):539-552.	"Nielsen KK, Nielsen JE, Madrid SM, Mikkelsen JD."	New antifungal proteins from sugar beet (Beta vulgaris L.) showing homology to non-specific lipid transfer proteins.
DRAMP01046	GYGGHGGHGGHGGHGGHGGHGHGGGGHG	28	Shepherin I (fragement of shep-GRP; Plants)	No entry found	Not found	GRP	Capsella bursa-pastoris (shepherd's purse)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Not found	Not found	"Circular dichroism (CD) spectra of shepherin I showes that shepherin I in 50% trifluoroethanol has 66.7% random coils, without any alpha-helices."	None	"Function: These antimicrobial peptides exhibit antimicrobial activity against Gram-negative bacteria and fungi.
Tissue specificity: Expressed in roots but not in leaves and stems."	"Gram-negative bacteria: Erwinia herbicola (IC50=62 ?g/ml), Escherichia coli (IC50<2.5 ?g/ml), Pseudomonas putida (IC50<2.5 ?g/ml), Pseudomonas syringae (IC50<2.5 ?g/ml), Salmonella typhimurium (IC50<2.5 ?g/ml), Serratia sp. (IC50=8 ?g/ml).##Fungi: Candida albicans (IC50=8 ?g/ml), Cryptococcus neoformans (IC50<2.5 ?g/ml), Saccharomyces cerevisiae (IC50<7 ?g/ml), Alternaria alternata (IC50<7 ?g/ml), Aspergillus flavus (IC50=65 ?g/ml), Fusarium culmorum (IC50=72 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11117262	Plant Mol Biol. 2000 Sep;44(2):187-197.	"Park CJ, Park CB, Hong SS, Lee HS, Lee SY, Kim SC."	"Characterization and cDNA cloning of two glycine- and histidine-rich antimicrobial peptides from the roots of shepherd's purse, Capsella bursa-pastoris."
DRAMP01047	GYHGGHGGHGGGYNGGGGHGGHGGGYNGGGHHGGGGHG	38	shepherin II (fragement of shep-GRP; Plants)	No entry found	Not found	GRP	Capsella bursa-pastoris (shepherd's purse)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Not found	Not found	"Circular dichroism (CD) spectra of shepherin II showes that shepherin II in 50% trifluoroethanol has 75% random coils, without any alpha-helices."	None	"Function: These antimicrobial peptides exhibit antimicrobial activity against Gram-negative bacteria and fungi.
Tissue specificity: Expressed in roots but not in leaves and stems."	"Gram-negative bacteria: Erwinia herbicola (IC50=25 ?g/ml), Escherichia coli (IC50<2.5 ?g/ml), Pseudomonas putida (IC50<2.5 ?g/ml), Pseudomonas syringae (IC50<2.5 ?g/ml), Salmonella typhimurium (IC50=65 ?g/ml), Serratia sp. (IC50<2.5 ?g/ml).##Fungi: Candida albicans (IC50=5 ?g/ml), Cryptococcus neoformans (IC50<2.5 ?g/ml), Saccharomyces cerevisiae (IC50=3 ?g/ml), Aspergillus flavus (IC50=60 ?g/ml), Fusarium culmorum (IC50=68 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11117262	Plant Mol Biol. 2000 Sep;44(2):187-197.	"Park CJ, Park CB, Hong SS, Lee HS, Lee SY, Kim SC."	"Characterization and cDNA cloning of two glycine- and histidine-rich antimicrobial peptides from the roots of shepherd's purse, Capsella bursa-pastoris."
DRAMP01048	HTPTPTPICKSRSHEYKGRCIQDMDCNAACVKESESYTGGFCNGRPPFKQCFCTKPCKRERAAATLRWPGL	71	Sd5 (sugarcane defensin 5; Plant defensin)	No entry found	Not found	Not found	Saccharum officinarum (Sugarcane)	"Antimicrobial, Antifungal"	Not found	Combine helix and strand structure	"Based on circular dichroism (CD) and nuclear magnetic resonance (NMR) spectroscopy showed that the structures of these Sds were compatible with alpha/beta proteins, a feature expected for plant defensins."	2KSK resolved by NMR.	"Function: Sd5 is active against fungi, but not against bacteria."	Fungi: Neurospora crassa and Fusarium solani (IC50=10-15 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18618271	Plant Mol Biol. 2008 Nov;68(4-5):321-335.	"De-Paula VS, Razzera G, Medeiros L, Miyamoto CA, Almeida MS, Kurtenbach E, Almeida FC, Valente AP."	Evolutionary relationship between defensins in the Poaceae family strengthened by the characterization of new sugarcane defensins.
DRAMP01049	RHRHCFSQSHKFVGACLRESNCENVCKTEGFPSGECKWHGIVSKCHCKRIC	51	Sd3 (sugarcane defensin 3; Plant defensin)	No entry found	Not found	Not found	Saccharum officinarum (Sugarcane)	"Antimicrobial, Antifungal"	Not found	Combine helix and strand structure	"Based on circular dichroism (CD) and nuclear magnetic resonance (NMR) spectroscopy showed that the structures of these Sds were compatible with alpha/beta proteins, a feature expected for plant defensins."	None	"Function: Sd3 is active against fungi, but not against bacteria."	Fungi: Neurospora crassa and Aspergillus niger (IC50=1-3.5 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18618271	Plant Mol Biol. 2008 Nov;68(4-5):321-335.	"De-Paula VS, Razzera G, Medeiros L, Miyamoto CA, Almeida MS, Kurtenbach E, Almeida FC, Valente AP."	Evolutionary relationship between defensins in the Poaceae family strengthened by the characterization of new sugarcane defensins.
DRAMP01050	RYCLSQSHRFKGLCMSSSNCANVCQTENFPGGECKADGATRKCFCKKIC	49	Sd1 (sugarcane defensin 1; Plant defensin)	B2CNV2	Not found	PDEF	Saccharum officinarum (Sugarcane)	"Antimicrobial, Antifungal"	Predicted	Combine helix and strand structure	"Based on circular dichroism (CD) and nuclear magnetic resonance (NMR) spectroscopy showed that the structures of these Sds were compatible with alpha/beta proteins, a feature expected for plant defensins."	None	"Function: Sd1 is active against fungi, but not against bacteria."	"Fungi: Neurospora crassa, Aspergillus niger, Fusarium solani (IC50=1-2 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18618271##PubMed ID is not available	Plant Mol Biol. 2008 Nov;68(4-5):321-335.##Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.	"De-Paula VS, Razzera G, Medeiros L, Miyamoto CA, Almeida MS, Kurtenbach E, Almeida FC, Valente AP.##Padovan L, Segat L, Tossi A, Crovella S."	Evolutionary relationship between defensins in the Poaceae family strengthened by the characterization of new sugarcane defensins.##Novel plant-defensin from sugarcane (Saccharum officinarum).
DRAMP01051	KSTCKAESNTFPGLCITKPPCRKACLSEKFTDGKCSKILRRCICYKPC	48	NpThio1 (Plant defensin)	No entry found	Not found	Not found	Nicotiana excelsior	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Plant Physiol 1997; 115:314.	"Yamada S, Komori T, Imaseki H."	Unknown
DRAMP01052	KDCKTESNTFPGICITKPPCRKACIKEKFTDGHCSKILRRCLCTKPC	47	NeThio2 (Plant defensin)	No entry found	Not found	Not found	Nicotiana excelsior	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Plant Physiol 1997; 115:314.	"Yamada S, Komori T, Imaseki H."	Unknown
DRAMP01053	ATITFTNKCTRTVWPGG	17	Thaumatin-like protein (CdTLP; Plants)	P84334	Not found	Not found	Cassia didymobotrya (Popcorn cassia)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity.
Induction: By salicylic acid and by laminarin oligosaccharides.
PTM: Contains one disulfide bond (By similarity)."	"Fungi: Candida albicans 586 (EC50=6.2 ?M), Candida parapsilosis ATCC 22019 (EC50=2.2 ?M), Candida krusei ATCC 14243 (EC50=2.5 ?M), C. krusei 80 (EC50=5.4 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17056265	Plant Physiol Biochem. 2006 Oct;44(10):604-610.	"Vitali A, Pacini L, Bordi E, De Mori P, Pucillo L, Maras B, Botta B, Brancaccio A, Giardina B."	Purification and characterization of an antifungal thaumatin-like protein from Cassia didymobotrya cell culture.
DRAMP01054	QNICPRVNRIVTPCVAYGLGRAPIAPCCRALNDLRFVNTRNLRRAACRCLVGVVNRNPGLRRNPRFQNIPRDCRNTFVRPFWWRPRIQCGRINLTDKLIYL	105	Antimicrobial protein Ace-AMP1 (Ace-AMP1; Plant defensin)	Q41258	Not found	Not found	Allium cepa (onion)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Bridge	Not found	None	"Function: Antifungal and antibacterial activity against the Gram-positive bacteria: B. megaterium and S. lutea.
PTM: Contains four disulfide bonds 4-49; 14-26; 28-73; 47-89."	"Gram-positive bacteria: Bacillus megaterium, Sarcina Lutea.##Fungi (SMF-, SMF+): Alternaria brassicola (IC50=2.5, 1.5 ?g/ml), Ascockyta pisi (IC50=1, 10 ?g/ml), Botrytis cinerea (IC50=3, 7 ?g/ml), Colletotrickum lindemutkianum (IC50=1.5, 1.5 ?g/ml), Fusarium culmorum (IC50=6, 10 ?g/ml), Fusarium oxysporum fsp. pisi (IC50=3.5, 4 ?g/ml), Fusarium oxysporum fsp. lycopersici (IC50=3, 10 ?g/ml),Nectria haematococca (IC50=3.5, 7 ?g/ml),Phoma betae (IC50=1.5, 7 ?g/ml), Pyrenopkora tritici-repentis (IC50=3, 3.5 ?g/ml), Pyricularia oryzae (IC50=3, 7 ?g/ml), Verticillium dahliae (IC50=0.25, 0.5 ?g/ml).##[NOTE: SMF- = Synthetic growth Medium with low ionic strength; SMF+ = Synthetic growth Medium supplemented with with 1 mM CaCl2, 50 mM KC1]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7480341##9521681	Plant Physiol. 1995 Oct;109(2):445-455.##Biochemistry. 1998 Mar 17;37(11):3623-3637.	"Cammue BP, Thevissen K, Hendriks M, Eggermont K, Goderis IJ, Proost P, Van Damme J, Osborn RW, Guerbette F, Kader JC, et al.##Tassin S, Broekaert WF, Marion D, Acland DP, Ptak M, Vovelle F, Sodano P."	"A potent antimicrobial protein from onion seeds showing sequence homology to plant lipid transfer proteins.##Solution structure of Ace-AMP1, a potent antimicrobial protein extracted from onion seeds. Structural analogies with plant nonspecific lipid transfer proteins."
DRAMP01055	AGCIKNGGRCNASAGPPYCCSSYCFQIAGQSYGVCKNR	38	P. americana AMP (Pa-AMP-1; PAFP-S; Cys-rich; Plant defensin)	"P81418, O82728"	Belongs to the AMP family	Not found	Phytolacca americana (American pokeweed) (Phytolacca decandra)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Beta strand (3 strands; 13 residues)	"The global fold involves a cystine-knotted three-stranded antiparallel beta-sheet (residues 8-10, 23-27, 32-36), a flexible loop (residues 14-19), and four beta-reverse turns (residues 4-8, 11-14, 19-22, 28-32). This structure features all the characteristics of the knottin fold. It is the first structural model of an antifungal peptide that adopts a knottin-type structure. "	1DKC resolved by NMR.	"Function: Possesses antifungal activity.
Tissue specificity: Seed specific.
Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.
PTM: Contains three disulfide bonds: 3-20; 10-24; 19-35. "	"Gram-positive bacteria: Bacillus megaterium (IC50=8 ?g/ml), Staphyanococcus sp. (IC50=11 ?g/ml).##Fungi: Alternaria panax, Fusarium sp., Rhizoctonia solani."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10759497##11551192	Plant Physiol. 2000 Apr;122(4):1015-1024.##Biochemistry. 2001 Sep 18;40(37):10973-10978.	"Liu Y, Luo J, Xu C, Ren F, Peng C, Wu G, Zhao J.##Gao GH, Liu W, Dai JX, Wang JF, Hu Z, Zhang Y, Wang DC."	"Purification, characterization, and molecular cloning of the gene of a seed-specific antimicrobial protein from pokeweed.##Solution structure of PAFP-S: a new knottin-type antifungal peptide from the seeds of Phytolacca americana."
DRAMP01056	ELCEKASQTWSGTCGKTKHCDDQCKSWEGAAHGACHVRDGKHMCFCYFNC	50	Ha-DEF1 (H. annuus defensin 1; Plants)	No entry found	Not found	Not found	Helianthus annuus (sunflower)	"Antimicrobial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Fungi: Saccharomyces cerevisiae.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17375322	Planta. 2007 Aug;226(3):591-600.	"de Z?licourt A, Letousey P, Thoiron S, Campion C, Simoneau P, Elmorjani K, Marion D, Simier P, Delavault P."	"Ha-DEF1, a sunflower defensin, induces cell death in Orobanche parasitic plants."
DRAMP01057	XXTKFDFFTLALQXPAXF	18	30 kDa antifungal protein (Plants)	Q10722	Not found	Not found	Engelmannia peristenia (Engelmann's daisy) (Engelmannia pinnatifida)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity against the plant fungal pathogens. Does not have antifungal activity against the human pathogen C. albicans. Does not have ribonuclease activity.
Tissue specificity: Leaves.
Developmental stage: Expressed in young plants, no expression in mature plants.
Miscellaneous: Resistant to heat and proteolysis.
Biophysicochemical properties: Temperature dependence (Thermostable)."	"Fungi: Gaeumannomyces graminis, Phytophthora infestans, Phytophthora megasperma, Sclerotinia sclerotiorum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8670144	Biochem J. 1996 Jun 15;316 ( Pt 3):723-727.	"Huynh QK, Borgmeyer JR, Smith CE, Bell LD, Shah DM."	Isolation and characterization of a 30 kDa protein with antifungal activity from leaves of Engelmannia pinnatifida.
DRAMP01058	ATFDIQNKXTYTVWAAAWAPSYPGGXKQLD	30	Antifungal protein (Plants)	P84061	Not found	Not found	Diospyros texana (Texas persimmon)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity against P. infestans.
Tissue specificity: Expressed in the skin and the flesh but not the seed of the fruit.
Developmental stage: Overripe fruit."	Phytophthora infestans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8048935	Biochem Biophys Res Commun. 1994 Jul 29;202(2):666-672.	"Vu L, Huynh QK."	Isolation and characterization of a 27-kDa antifungal protein from the fruits of Diospyros texana.
DRAMP01062	SESILIVHQQQSRSSGS	17	Putative antimicrobial protein 3 (Cm-p2; Plants)	B3EWI8	Not found	Not found	Cenchritis muricatus (Beaded periwinkle)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: This peptide demonstrated the capacity to prevent the development of yeasts and filamentous fungi. Otherwise, Cm-p1 displayed no toxic effects against mammalian cells."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22210491	Biochimie. 2012 Apr;94(4):968-974.	"L?pez-Abarrategui C, Alba A, Silva ON, Reyes-Acosta O, Vasconcelos IM, Oliveira JT, Migliolo L, Costa MP, Costa CR, Silva MR, Garay HE, Dias SC, Franco OL, Otero-Gonz?lez AJ."	Functional characterization of a synthetic hydrophilic antifungal peptide derived from the marine snail Cenchritis muricatus.
DRAMP01065	NSMERVEELRKKLQD	15	Chitin-binding protein HM30 (Plants)	P83630	Belongs to the parathyroid hormone family	Not found	Hydrangea macrophylla (Bigleaf hydrangea)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity against phytopathogenic fungi. Has no chitinase or agglutination activities.	"Fungi: Alternria alternate, Alternaria cucumerina, Aspergillus niger, Collectotrichum gossypii, Fusarium oxysporum, F. oxysporum subsp melonis, Fusarium moniliforme, Thanatephorus cucumeris, Verticillium dahliae, Pyricularia oryzae Cav.."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	11812226	Protein Expr Purif. 2002 Feb;24(1):76-82.	"Yang Q, Gong ZZ."	Purification and characterization of an ethylene-induced antifungal protein from leaves of Guilder rose (Hydrangea macrophylla).
DRAMP01067	KQTENLADTY	10	Coccinin (Plant defensin)	P84785	 Belongs to the DEFL family	Not found	Phaseolus coccineus (Scarlet runner bean) (Phaseolus multiflorus)	"Antimicrobial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	Function: Has strong antifungal activity. Inhibits the proliferation of leukemia cells in vitro. Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase (IC50=41 ?M). Lacks mitogenic activity towards murine splenocytes.	"Fungi: Fusarium oxysporum (IC50=81¡À7 ?M), Mycosphaerella arachidicola (IC50=75¡À5 ?M), Physalospora piricola (IC50=89¡À4 ?M), Rhizoctomia solani (IC50=134¡À2 ?M), Botrytis cinerea (IC50=109¡À5 ?M), Coprinus comatus (IC50=122¡À7 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15572193	Peptides. 2004 Dec;25(12):2063-2068.	"Ngai PH, Ng TB."	"Coccinin, an antifungal peptide with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from large scarlet runner beans."
DRAMP01070	AIPCGQVNSALASCVSYAKGSGASPPGACCSGVRRLAGLARSTADKQAACRCIKSAAGGLNPGKAASIPSKCGVSIPYSISASVDCSKIH	90	Non-specific lipid-transfer protein (Plants)	Q1KMV1	Belongs to the plant LTP family	Not found	Triticum aestivum (Wheat)	"Antimicrobial, Antifungal"	Homology	Not found	Not found	None	Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	18257684	Mol Plant Microbe Interact. 2008 Mar;21(3):346-360.	"Sun JY, Gaudet DA, Lu ZX, Frick M, Puchalski B, Laroche A."	Characterization and antifungal properties of wheat nonspecific lipid transfer proteins.
DRAMP01084	ILGAILPLVSGLLSNKL	17	"Alyteserin-2b (toads, amphibians, animals)"	No entry found	Not found	Not found	Alytes obstetricans (European midwife toad)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Function: Amtimicrobial peptide. (By similarity)	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19463738	Peptides. 2009 Jun;30(6):1069-1073.	"Conlon JM, Demandt A, Nielsen PF, Leprince J, Vaudry H, Woodhams DC."	The alyteserins: two families of antimicrobial peptides from the skin secretions of the midwife toad Alytes obstetricans (Alytidae).
DRAMP01086	ILGAILPLVSGLLSSKL	17	"Alyteserin-2c (toads, amphibians, animals)"	No entry found	Not found	Not found	Alytes obstetricans (European midwife toad)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Function: Amtimicrobial peptide. (By similarity)	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19463738	Peptides. 2009 Jun;30(6):1069-1073.	"Conlon JM, Demandt A, Nielsen PF, Leprince J, Vaudry H, Woodhams DC."	The alyteserins: two families of antimicrobial peptides from the skin secretions of the midwife toad Alytes obstetricans (Alytidae).
DRAMP01087	GLKDIFKAGLGSLVKNIAAHVAN	23	"Alyteserin-1d (toads, amphibians, animals)"	No entry found	Not found	Not found	Alytes obstetricans (European midwife toad)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Function: Amtimicrobial peptide. (By similarity)	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19463738	Peptides. 2009 Jun;30(6):1069-1073.	"Conlon JM, Demandt A, Nielsen PF, Leprince J, Vaudry H, Woodhams DC."	The alyteserins: two families of antimicrobial peptides from the skin secretions of the midwife toad Alytes obstetricans (Alytidae).
DRAMP01112	GIGGALLSAGKSALKGLAKGLAEHFAN	27	"Maximin-11 (Maximin-6; toads, amphibians, animals)"	"Q58T41, P83085"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Function: It has little hemolytic activity 	Yeast: Candida albicans.	[Ref:11835991]Little hemolytic activity at 50 ¦Ìg/ml against red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-1229.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01113	GIGAKILGGVKTALKGALKELASTYVN	27	"Maximin-7 (toads, amphibians, animals)"	"Q58T58, Q58T74"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Function: It has little hemolytic activity. 	[Swiss_Prot Entry Q58T58]Yeast: Candida albicans	[Ref:15770703]Little hemolytic activity	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01114	GIGTKILGGLKTAVKGALKELASTYVN	27	"Maximin-8 (toads, amphibians, animals)"	Q58T56	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Function: It has little hemolytic activity. 	[Ref.15770703]Yeast: Candida albicans	[Ref:15770703]Little hemolytic activity	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01115	GIGRKFLGGVKTTFRCGVKDFASKHLY	27	"Maximin-9 (toads, amphibians, animals)"	Q58T55	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11835991	FEBS Lett. 2005 Aug 15;579(20):4443-4448	"Wen-Hui Lee, Jie Zhang, Ying-Xia Zhang, Yang Jin, Ren Lai and Yun Zhang."	"Maximin 9, a novel free thiol containing antimicrobial peptide with antimycoplasma activity from frog Bombina maxima"
DRAMP01116	GIGGALLSAGKSALKGLAKGLAEHFAS	27	"Maximin-10 (toads, amphibians, animals)"	"Q58T45, Q58T39"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Function: Maximin-10 shows antimicrobial activity against bacteria and against the fungus C. albicans. It has little hemolytic activity (By similarity).	[Swiss_Prot Entry Q58T45]Yeast: Candida albicans	[Ref:11835991]Little hemolytic activity at 50 ¦Ìg/ml against red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-1229.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01117	GIGTKIIGGLKTAVKGALKELASTYVN	27	"Maximin-11 (toads, amphibians, animals)"	Q58T51	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01118	GIGGALLSAGKAALKGLAKGFAEHF	25	"Maximin y type 2 (toads, amphibians, animals)"	Q58T94	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01119	GIGGALLSAGKSALKGLAKGFAEHF	25	"Maximin-y (toads, amphibians, animals)"	Q58T91	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01120	ILGPVLSLVGSALGGLIKKI	20	"Maximin-Hv (toads, amphibians, animals)"	"Q58T91 , Q58T89 , Q58T94"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01121	ILGPVLGLVSNAIGGLIKKI	20	"Maximin-Hw (toads, amphibians, animals)"	Q58T92	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01122	GIGGALLSAGKSALKGLAKGLVEHFAN	27	"Maximin-z (toads, amphibians, animals)"	Q58T90	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01128	ILGPVIGTIGNVLGGLLKNL	20	"Maximin-H6 (toads, amphibians, animals)"	Q58T72	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01129	ILGPVIKTIGGVIGGLLKNL	20	"Maximin-H7 (toads, amphibians, animals)"	Q58T56	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01130	ILGPVLGLVSNALGGLLKNI	20	"Maximin-H8 (toads, amphibians, animals)"	"Q58T86, Q58T49"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-1229.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01131	ILGPVLGLVSNALGGLIKKI	20	"Maximin-H9 (toads, amphibians, animals)"	"Q58T80, Q58T69"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-1229.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01132	ILGPVLGLVSNALGGLLKNL	20	"Maximin-H10 (toads, amphibians, animals)"	Q58T59	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Function: Shows strong hemolytic activity.	[Swiss_Prot Entry Q58T59]Yeast: Candida albicans	[Ref:11835991]90¨C100% hemolytic activity at 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01133	ILGPVLGLVGSALGGLIKKI	20	"Maximin-H11 (toads, amphibians, animals)"	"Q58T95, Q58T65, Q58T64, Q58T48"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Function: Shows strong hemolytic activity.	[Swiss_Prot Entry Q58T95]Yeast: Candida albicans	[Ref:11835991]90¨C100% hemolytic activity at 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-1229.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01134	ILGPVIKTIGGVLGGLLKNL	20	"Maximin-H13 (toads, amphibians, animals)"	Q58T58	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703	Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lee W.-H, Li Y, Lai R, Li S, Zhang Y, Wang W."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01135	LLGPVLGLVSNALGGLLKNI	20	"Maximin-H12 (toads, amphibians, animals)"	Q58T87	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11835991##15770703	Peptides. 2002 Mar;23(3):427-435.##Eur J Immunol. 2005 Apr;35(4):1220-1229.	"Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y.##Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W."	Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.##Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.
DRAMP01136	ILGPVLGLVGEPLGGLIKKI	20	"Maximin-H14 (toads, amphibians, animals)"	Q58T46	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-1229.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01137	ILGPVLGLVGNALGGLLKNL	20	"Maximin-H15 (toads, amphibians, animals)"	"Q58T43, Q58T39"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-1229.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01138	ILGPVLSLVGNALGGLIKKI	20	"Maximin-H16 (toads, amphibians, animals)"	"Q58T93, Q58T40"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Shows strong hemolytic activity. 	[Swiss_Prot Entry Q58T93]Yeast: Candida albicans	[Ref:11835991]90¨C100% hemolytic activity at 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-1229.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01193	FLPKLFAGIISKNF	14	"Andersonin-Y2 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Function: Weakly active against bacteria and fungi.	No MICs found in DRAMP database	[Ref:22029824]Not found	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01196	KEKLKLKCKAPKCYNDKLACT	21	"Andersonin-G1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Weakly active against bacteria and fungi and has no hemolytic activity under the test conditions.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC>200 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC>200 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC>200 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC>200 ?g/ml)."	[Ref:22029824]Non-hemolytic activity against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01197	ENMFNIKSSVESDSFWG	17	"Andersonin-N1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Weakly active against bacteria and fungi and has no hemolytic activity under the test conditions.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC>200 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC>200 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC>200 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC>200 ?g/ml)."	[Ref:22029824]Non-hemolytic activity against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01198	EMLKKKKEVKMERKT	15	"Andersonin-Q1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Odorrana andersonii (Golden crossband frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Weakly active against bacteria and fungi and has no hemolytic activity under the test conditions.	"[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC>200 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC>200 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC>200 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC>200 ?g/ml)."	[Ref:22029824]Non-hemolytic activity against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01212	SIITMTREAKLPQLWKQIACRLYNTC	26	"Pleurain-A3 (Pleurain A3; Frogs, amphibians, animals)"	A8B5P7	Not found	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has little hemolytic activity on red blood cells.
Tissue specificity: Expressed by the skin dorsal glands."	"[Swiss_Prot Entry A8B5P7]has activity against Gram-positive and -negative bacteria, and fungi"	[Ref:17764786]Little hemolytic activity on red blood cells even with peptide concentration up to 200 ¦Ìg/ml	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17764786	Peptides. 2007 Oct;28(10):2069-2074.	"Wang X, Song Y, Li J, Liu H, Xu X, Lai R, Zhang K."	A new family of antimicrobial peptides from skin secretions of Rana pleuraden.
DRAMP01213	SIITTTKEAKLPQLWKQIACRLYNTC	26	"Pleurain-A4 (Pleurain A4; Frogs, amphibians, animals)"	A8B5Q0	Not found	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has little hemolytic activity on red blood cells.
Tissue specificity: Expressed by the skin dorsal glands."	"[Swiss_Prot Entry A8B5Q0]has activity against Gram-positive and -negative bacteria, and fungi"	[Ref:17764786]Little hemolytic activity on red blood cells even with peptide concentration up to 200 ¦Ìg/ml	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17764786	Peptides. 2007 Oct;28(10):2069-2074.	"Wang X, Song Y, Li J, Liu H, Xu X, Lai R, Zhang K."	A new family of antimicrobial peptides from skin secretions of Rana pleuraden.
DRAMP18404	INWLKLGKMVIDAL	14	"Polybia-MPII (mastoparan; insects, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	"venom, the social wasp, Pseudopolybia vespiceps testacea"	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"		Not found	Not found	None	Fuction: It demonstrated a potent ability to suppress endotoxin lipopolysaccharide (LPS)-mediated induction of the pro-inflammatory cytokine TNF-a in human peripheral blood mononuclear cells by 94%. It also completely protected mice against an invasive S. aureus infection when given I.P. to mice at 8 mg/kg 4 hr prior to initiation of the infection. Surface immobilization led to enhanced antimicrobial activity against P. aeruginosa.	Gram-positive bacteria: S. aureus(MIC 2.3 ug/ml);##Gram-negative bacteria: P. aeruginosa (MIC 9 ug/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	28108242	Int J Antimicrob Agents. 2017 Feb;49(2):167-175. 2017	"Silva JC, Neto LM, Neves RC, Gon?alves JC, Trentini MM, Mucury-Filho R, Smidt KS, Fensterseifer IC, Silva ON, Lima LD, Clissa PB, Vilela N, Guilhelmelli F, Silva LP, Rangel M, Kipnis A, Silva-Pereira I, Franco OL, Junqueira-Kipnis AP, Bocca AL, Mortari MR."	"Evaluation of the antimicrobial activity of the mastoparan Polybia-MPII isolated from venom of the social wasp Pseudopolybia vespiceps testacea (Vespidae, Hymenoptera)"
DRAMP01338	FLPMLAGLAANFLPKLFCKITKKC	24	"Amolopin-1a (Frogs, amphibians, animals)"	"A0SN41, A0SN38, A0SN39"	Not found	Not found	Amolops loloensis (Rufous-spotted torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Staphylococcus aureus, Bacillus dysenteriae;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17000029	Peptides. 2006 Dec;27(12):3085-3091. 	"Lu Y, Li J, Yu H, Xu X, Liang J, Tian Y, Ma D, Lin G, Huang G, Lai R."	"Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis."
DRAMP01342	FLPIVGKLLSGLL	13	"Amolopin-2b (Frogs, amphibians, animals)"	"A0SN47, A0SN48"	Not found	Not found	Amolops loloensis (Rufous-spotted torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Staphylococcus aureus, Bacillus dysenteriae;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17000029	Peptides. 2006 Dec;27(12):3085-3091. 	"Lu Y, Li J, Yu H, Xu X, Liang J, Tian Y, Ma D, Lin G, Huang G, Lai R."	"Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis."
DRAMP01343	FLPMLAGLAANLLPKLFCKITKKC	24	"Amolopin-1c (Frogs, amphibians, animals)"	A0SN43	Not found	Not found	Amolops loloensis (Rufous-spotted torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Staphylococcus aureus, Bacillus dysenteriae;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17000029	Peptides. 2006 Dec;27(12):3085-3091. 	"Lu Y, Li J, Yu H, Xu X, Liang J, Tian Y, Ma D, Lin G, Huang G, Lai R."	"Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis."
DRAMP01344	LLPIVGKLLSGLL	13	"Amolopin-2c (Frogs, amphibians, animals)"	A0SN50	Not found	Not found	Amolops loloensis (Rufous-spotted torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Staphylococcus aureus, Bacillus dysenteriae;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17000029	Peptides 2006; 27: 3085-3091.	Lu Y et al Lai R2006	"Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis"
DRAMP01345	FLPMLAGLAANFLPELFCKITKKC	24	"Amolopin-1d (Frogs, amphibians, animals)"	A0SN44	Not found	Not found	Amolops loloensis (Rufous-spotted torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Has antibacterial against Gram-positive and Gram-negative bacteria. Also has antifungal activity against C. albicans.	"Gram-positive bacteria: Staphylococcus aureus, Bacillus dysenteriae;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17000029	Peptides. 2006 Dec;27(12):3085-3091. 	"Lu Y, Li J, Yu H, Xu X, Liang J, Tian Y, Ma D, Lin G, Huang G, Lai R."	"Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis."
DRAMP01388	GFSPNLPGKGLRIS	14	"Odorranain-R1 (OdR1; Frogs, amphibians, animals)"	A6MBR8 	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	Function: Odorranain-R1 appears to be narrowly antifungal with low potency against Candida albicans.	[Ref.17272268] Yeast: Candida albicans (MIC=50 ¦Ìg/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01425	GLLSGVLGVGKKVDCGLSGLC	21	"Nigrocin-OG21 (frog, amphibians, animals)"	No entry found	Not found	Not found	Odorrana grahami (Yunnanfu frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Function: Showes an effect on HIV when applied in combination with OdK1.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01444	GLLDSIKGMAISAGKGALQNLLKVASCKLDKTC	33	"Nigrocin-1 (Frogs, amphibians, animals)"	P0C008	Not found	Not found	Pelophylax nigromaculatus (Black-spotted frog) (Rana nigromaculata) (frog skin active peptide)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. Has weak hemolytic activity.
Tissue specificity: Expressed by the skin dorsal glands.
PTM: Contains one disulfide bond 27-33. (By similarity)"	"[Ref.11682065]Gram-positive bacterium: Micrococcus luteus(MIC=2.5¦Ìg/ml);##Gram-negative bacteria: Shigella dysenteriae(MIC=10¦Ìg/ml), Klebsiella pneumoniae(MIC=10¦Ìg/ml), Pseudomonas aeruginosa(MIC=75¦Ìg/ml), Salmonella typhimurium(MIC=22.5¦Ìg/ml), Proteus mirabilis(MIC>200¦Ìg/ml), Serratia marcescens(MIC>200¦Ìg/ml);##Yeast: Candida albicans(MIC=100¦Ìg/ml)."	[Ref:11682065]1.1% hemolytic activity at 100¦Ìg/ml against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11682065	FEBS Lett. 2001 Oct 19;507(1):95-100.	"Park S, Park SH, Ahn HC, Kim S, Kim SS, Lee BJ, Lee BJ."	"Structural study of novel antimicrobial peptides, nigrocins, isolated from Rana nigromaculata."
DRAMP01445	GLLSKVLGVGKKVLCGVSGLC	21	"Nigrocin-2 (Nigrocin-2LVa; Frogs, amphibians, animals)"	P0C009	Not found	Not found	Rana nigromaculata (Black-spotted frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Thanks to its single linear amphipathic alpha-helix, may integrate into membrane phospholipids, leading to lysis of the membrane. Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. Has weak hemolytic activity.
Tissue specificity: Expressed by the skin dorsal glands.
PTM: Contains one disulfide bond 15-21. (By similarity)"	"[Ref.11682065]Gram-positive bacterium: Micrococcus luteus(MIC=2.5¦Ìg/ml);##Gram-negative bacteria: Shigella dysenteriae(MIC=10¦Ìg/ml), Klebsiella pneumoniae(MIC=10¦Ìg/ml), Pseudomonas aeruginosa(MIC=100¦Ìg/ml), Salmonella typhimurium(MIC=22.5¦Ìg/ml), Proteus mirabilis(MIC>200¦Ìg/ml), Serratia marcescens(MIC>200¦Ìg/ml);##Yeast: Candida albicans(MIC=150¦Ìg/ml)."	[Ref:11682065] It has 0.9% hemolytic activity at 100¦Ìg/ml against human red blood cells	Cyclic	Free	Cyclization (Cys15 and Cys21)	Disulfide bond between Cys15 and Cys21.	L	No cytotoxicity information found	Cell membrane	11682065	FEBS Lett. 2001 Oct 19;507(1):95-100.	"Park S, Park SH, Ahn HC, Kim S, Kim SS, Lee BJ, Lee BJ."	"Structural study of novel antimicrobial peptides, nigrocins, isolated from Rana nigromaculata."
DRAMP01498	GLFSKFAGKGIKNFLNKGVKHIGKE	25	"Esculentin-1-OA6 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01500	KISGKAIKNLFIKGAKNVGKEVGMDVVRTGIDVVGCKIKGEC	42	"Esculentin-1-OR2 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana andersonii (Chinese odorous frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP01512	QVFTLIKGATQLIRKTLGEQ	20	"Esculentin-2-OR6 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Odorrana rotodora (Chinese odorous frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22029824	J Proteome Res. 2012 Jan 1;11(1):306-319.	"Yang X, Lee WH, Zhang Y."	Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.
DRAMP18312	MTDANVDARRARAPHGISGAIAGVVAGCAATIEIGCVEGAIAGIGPSGIASMIAALWTCRSKYRRFSSGSGYVMLLSWSAEFVFGYFIGCRCGFLLSQK	99	Propionicin PLG-1(Bacteriocin)	I2HA02	Not found	plg-1	Propionibacterium thoeniiP127	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"		Not found	Not found	None	"Propionicin PLG-1 is active against a variety of microorganisms such as propionibacteria, as well as many other gram-positive and gram-negative bacteria and even fungi.Propionicin PLG-1 is stable after long-term storage in a dry or frozen state and rapidly kills sensitive cells upon exposure in culture medium or skim milk."	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11010864	Appl Environ Microbiol. 2000 Oct;66(10):4230-6.	"Faye T, Langsrud T, Nes IF, Holo H."	"Biochemical and genetic characterization of propionicin T1, a new bacteriocin from Propionibacterium thoenii."
DRAMP01519	GVFSFLKTGAKLLGSTLLKMAGKAGAEHLACKATNQC	37	"Esculentin-2PRa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pretiosa (North American oregon spotted frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Shows antibacterial activity against both Gram-positive and Gram-negative bacteria and against the fungus C. albicans. 	Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Staphylococcus aureus.##Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys31 and Cys37)	Disulfide bond between Cys31 and Cys37.	L	No cytotoxicity information found	Not found	21295070	Dev Comp Immunol. 2011 Jun;35(6):644-649.	"Conlon JM, Mechkarska M, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, Hayes MP, Padgett-Flohr G."	Host defense peptides in skin secretions of the Oregon spotted frog Ranapretiosa: implications for species resistance to chytridiomycosis.
DRAMP01559	GLFKVLGSVAKHLLPHVVPVIAEKL	25	"Caerin-1.8 (Frogs, amphibians, animals)"	P81251	Belongs to the frog skin active peptide family (Caerin subfamily)	Not found	Litoria chloris (Blue-thighed frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Protein level	Alpha helix 	Not found	None	"Function: Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes. Each caerin displays a different antimicrobial specificity.
Tissue specificity: Expressed by the skin dorsal glands.
Domain: Contains two amphipathic alpha helix regions separated by a region of less-defined helicity and greater flexibility (By similarity).
PTM: C-terminal amidation."	Litoria chloris	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9516047	J Pept Res. 1998 Feb;51(2):121-126.	"Steinborner ST, Currie GJ, Bowie JH, Wallace JC, Tyler MJ."	New antibiotic caerin 1 peptides from the skin secretion of the Australian tree frog Litoria chloris. Comparison of the activities of the caerin 1 peptides from the genus Litoria.
DRAMP01629	GWMSKIASGIGTFLSGVQQG	20	"Phylloxin-S1 (Frogs, amphibians, animals)"	No entry found	Belongs to the Phyllomedusinae subfamily	Not found	Phyllomedusa sauvagii (Waxy Monkey Leaf Frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18644413	Peptides. 2008 Nov;29(11):2074-2082.	"Amiche M, Ladram A, Nicolas P."	A consistent nomenclature of antimicrobial peptides isolated from frogs of the subfamily Phyllomedusinae.
DRAMP01630	AVWKDFLKNIGKAAGKAVLNSVTDMVNE	28	"Dermaseptin-LI1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Phyllomedusa hypochondrialis (Orange legged leaf frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18644413	Peptides. 2008 Nov;29(11):2074-2082.	"Amiche M, Ladram A, Nicolas P."	A consistent nomenclature of antimicrobial peptides isolated from frogs of the subfamily Phyllomedusinae.
DRAMP01631	GLWKSLLKNVGKAAGKAALNAVTDMVNQ	28	"Dermaseptin-S7 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Phyllomedusa sauvagei (Sauvage's leaf frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14599725	Regul Pept. 2003 Nov 15;116(1-3):139-146.	"Chen T, Tang L, Shaw C."	Identification of three novel Phyllomedusa sauvagei dermaseptins (sVI-sVIII) by cloning from a skin secretion-derived cDNA library.
DRAMP01632	ALWKTMLKKLGTVALHAGKAALGAAADTISQ	31	"Dermaseptin-S8 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Phyllomedusa sauvagei (Sauvage's leaf frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Alpha helix	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14599725	Regul Pept. 2003 Nov 15;116(1-3):139-146.	"Chen T, Tang L, Shaw C."	Identification of three novel Phyllomedusa sauvagei dermaseptins (sVI-sVIII) by cloning from a skin secretion-derived cDNA library.
DRAMP01654	GLWSKIKEAGKAVLTAAGKAALGAVSDAV	29	"Dermaseptin-B8 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Phyllomedusa bicolor (Two-colored leaf frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9305726	FEBS Lett. 1997 Sep 1;414(1):27-32.	"Vouille V, Amiche M, Nicolas P."	"Structure of genes for dermaseptins B, antimicrobial peptides from frog skin. Exon 1-encoded prepropeptide is conserved in genes for peptides of highly different structures and activities."
DRAMP01669	ALWFTMLKKLGTMALHAGKAALGAAANTISQGTQ	34	"Dermaseptin-2 (DS II; Dermaseptin-S2, DS2; Frogs, amphibians, animals)"	P80278	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa sauvagei (Sauvage's leaf frog)	"Antimicrobial, Antibacterial, Antifungal, Antiprotozoal"	Protein level	Alpha helix	Not found	None	"Function: Possesses a potent antimicrobial activity against bacteria, fungi and protozoa. Probably acts by disturbing membrane functions with its amphipathic structure.
Tissue specificity: Expressed by the skin glands."	Aspergillus fumigatus.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8306981	Eur J Biochem. 1994 Jan 15;219(1-2):145-154.	"Mor A, Nicolas P."	Isolation and structure of novel defensive peptides from frog skin.
DRAMP01670	ALWKNMLKGIGKLAGKAALGAVKKLVGAES	30	"Dermaseptin-3 (DS III; Dermaseptin-S3, DS3; Frogs, amphibians, animals)"	P80279	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa sauvagei (Sauvage's leaf frog)	"Antimicrobial, Antibacterial, Antifungal, Antiprotozoal"	Protein level	Alpha helix	Not found	None	"Function: Possesses a potent antimicrobial activity against bacteria, fungi and protozoa. Probably acts by disturbing membrane functions with its amphipathic structure. Binds to healthy erythrocytes (this binding is receptor independent), but has no significant hemolytic activity. Does not bind to P. falciparum infected erythrocytes, but accumulates within the parasite. Kills the parasite, but has no hemolytic activity on the host cell.
Tissue specificity: Expressed by the skin glands."	"[Ref.9395500]Fungi: Aspergillus fumigatus;##Protozoa: Malarial parasite strain H (IC50=0.8 ?g/ml), Malarial parasite strain NF54 (IC50=0.26 ?g/ml)."	[Ref:8306981]No significant hemolytic activity against rabbit red blood cells;##[Ref:9395500]Non-hemolytic activity against human red blood cells.	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Binds to healthy erythrocytes (this binding is receptor independent).	8306981##9395500	Eur J Biochem. 1994 Jan 15;219(1-2):145-155.##J Biol Chem. 1997 Dec 12;272(50):31609-31616.	"Mor A, Nicolas P.##Ghosh JK, Shaool D, Guillaud P, Cic??ron L, Mazier D, Kustanovich I, Shai Y, Mor A."	Isolation and structure of novel defensive peptides from frog skin.##Selective cytotoxicity of dermaseptin S3 toward intraerythrocytic Plasmodium falciparum and the underlying molecular basis.
DRAMP01671	ALWMTLLKKVLKAAAKALNAVLVGANA	27	"Dermaseptin-4 (DS IV; Dermaseptin-S4, DS4; Frogs, amphibians, animals)"	P80280	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa sauvagei (Sauvage's leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral"	Protein level	Combine strand and Turn structure	Not found	None	"Function: Possesses a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, fungi, protozoa, and the enveloped herpes simplex virus type 1. Probably acts by disturbing membrane functions with its amphipathic structure. Has strong hemolytic activity. Does not bind to P. falciparum infected erythrocytes, but accumulates within the parasite.
Tissue specificity: Expressed by the skin glands.
Pharmaceutical use: Derivatives of this peptide may be used as therapeutic agents to treat bacterial infections and malaria, and to prevent infection by herpes simplex virus type 1 and HIV-1."	"[Swiss_Prot Entry P80280]Possesses a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, fungi, protozoa, and the enveloped herpes simplex virus type 1"	[Ref:11850249]IC50=20 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	healthy erythrocytes (this binding is receptor independent).	8306981##11850249##9395500	Eur J Biochem. 1994 Jan 15;219(1-2):145-154.##Antimicrob Agents Chemother. 2002 Mar;46(3):689-694.##J Biol Chem. 1997 Dec 12;272(50):31609-31616.	"Mor A, Nicolas P.##Navon-Venezia S, Feder R, Gaidukov L, Carmeli Y, Mor A.##Ghosh JK, Shaool D, Guillaud P, Cic??ron L, Mazier D, Kustanovich I, Shai Y, Mor A."	Isolation and structure of novel defensive peptides from frog skin.##Antibacterial properties of dermaseptin S4 derivatives with in vivo activity.##Selective cytotoxicity of dermaseptin S3 toward intraerythrocytic Plasmodium falciparum and the underlying molecular basis.
DRAMP01672	GLWSKIKTAGKSVAKAAAKAAVKAVTNAV	29	"Dermaseptin-5 (DS V; Dermaseptin-S5, DS5; Frogs, amphibians, animals)"	P80281	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa sauvagei (Sauvage's leaf frog)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"MOA: Probably acts by disturbing membrane functions with its amphipathic structure. Binds to healthy erythrocytes (this binding is receptor independent), and has strong hemolytic activity. Does not bind to P.falciparum infected erythrocytes, but accumulates within the parasite.
Pharmaceutical use: Derivatives of this peptide may be used as therapeutic agents to treat bacterial infections and malaria, and to prevent infection by herpes simplex virus type 1 and HIV-1."	"[Swiss_Prot Entry P80281]Possesses a potent antimicrobial activity against bacteria, fungi and protozoa"	[Ref:8306981]Show strong hemolytic activity against rabbit healthy erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8306981	Eur J Biochem. 1994 Jan 15;219(1-2):145-154.	"Mor A, Nicolas P."	Isolation and structure of novel defensive peptides from frog skin.
DRAMP01673	GLWSKIKETGKEAAKAAGKAALNKIAEAV	29	"Dermaseptin-1 (DStar 01; Frogs, amphibians, animals)"	P84921	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa tarsius (Brownbelly leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide, active against the Gram-positive bacterium S. aureus, the Gram-negative bacteria E. coli and P. aeruginosa, and the yeasts C. albicans and P. brasiliensis. Has hemolytic activity.
Tissue specificity: Expressed by the skin glands.
PTM: C-terminal amidation."	"[Swiss_Prot Entry P84921]Gram-positive bacteria: Staphylococcus aureus, Enterococcus faecalis;##Gram-neagtive bacterium: Pseudomonas aeruginosa.;##Fungi: Candida albicans and Paracoccidioides brasiliensis."	[Ref:PubMed ID is not available]40% hemolytic activity at 128 ?g/ml	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (AUG-2006) to UniProtKB.	"Prates M.V, Jardim D.P, Silva L.P, Gordo M, Leite J.R.S.A, Figueredo R.C.R, Amaral A.C, Felipe M.S.S, Bloch C. Jr."	Dermaseptins and phylloseptins from Phyllomedusa tarsius (Amphibia).
DRAMP01675	GLFKTLIKGAGKMLGHVAKQFLGSQGQPES	30	"Dermaseptin-3 (DStar 03; Frogs, amphibians, animals)"	P84923	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa tarsius (Brownbelly leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide, active against the Gram-positive bacterium S. aureus, the Gram-negative bacteria E. coli and P. aeruginosa, and the yeasts C. albicans and P. brasiliensis. Has hemolytic activity.
Tissue specificity: Expressed by the skin glands."	"[Swiss_Prot Entry P84923]Gram-positive bacteria: Staphylococcus aureus, Enterococcus faecalis;##Gram-neagtive bacterium: Pseudomonas aeruginosa;##Fungi: Candida albicans and Paracoccidioides brasiliensis."	[Ref:PubMed ID is not available]100% hemolytic activity at 128 ?g/ml	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (AUG-2006) to UniProtKB.	"Prates M.V, Jardim D.P, Silva L.P, Gordo M, Leite J.R.S.A, Figueredo R.C.R, Amaral A.C, Felipe M.S.S, Bloch C. Jr."	Dermaseptins and phylloseptins from Phyllomedusa tarsius (Amphibia).
DRAMP01677	GLWSKIKEAAKTAGKAAMGFVNEMV	25	"Dermaseptin-5 (DStar 05; Frogs, amphibians, animals)"	P84925	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa tarsius (Brownbelly leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial peptide, active against the Gram-positive bacterium S. aureus, the Gram-negative bacteria E. coli and P. aeruginosa, and the yeasts C. albicans and P. brasiliensis. Has hemolytic activity.
Tissue specificity: Expressed by the skin glands.
PTM: C-terminal amidation."	"[Swiss_Prot Entry P84925]Gram-positive bacteria: Staphylococcus aureus, Enterococcus faecalis;##Gram-neagtive bacterium: Pseudomonas aeruginosa;##Fungi: Candida albicans and Paracoccidioides brasiliensis."	[Ref:PubMed ID is not available]15% hemolytic activity at 128 ?g/ml	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (AUG-2006) to UniProtKB.	"Prates M.V, Jardim D.P, Silva L.P, Gordo M, Leite J.R.S.A, Figueredo R.C.R, Amaral A.C, Felipe M.S.S, Bloch C. Jr."	Dermaseptins and phylloseptins from Phyllomedusa tarsius (Amphibia).
DRAMP01710	ALWKTMLKKLGTVALHAGKAALGAAADTISQGA	33	"Dermaseptin DS VIII-like peptide (Frogs, amphibians, animals)"	P86280	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa burmeisteri (Brazilian common walking leaf frog)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	MOA: Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (APR-2009) to UniProtKB	"Conceicao K, Klitzke C.F, Brito R.C, Andrade D.F, Junca F.A, Biondi I, Lopes-Ferreira M."	Identification of peptides from Phyllomedusa burmesteri skin secretomics by nano LC MS/MS.
DRAMP01711	ALWKNMLKGIGKLAGKAALGAVK	23	"Dermaseptin III-like peptide (Frogs, amphibians, animals)"	P86281	Belongs to the frog skin active peptide family (Dermaseptin subfamily)	Not found	Phyllomedusa burmeisteri (Brazilian common walking leaf frog)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	MOA: Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (APR-2009) to UniProtKB.	"Conceicao K, Klitzke C.F, Brito R.C, Andrade D.F, Junca F.A, Biondi I, Lopes-Ferreira M."	Identification of peptides from Phyllomedusa burmesteri skin secretomics by nano LC MS/MS.
DRAMP01713	VHLEEILLLLFFLGTISLSLCEEERDADEEENEVSGYAANVNVKRCGYKHGRANCGRG	58	"OGA1 antimicrobial peptide (Frogs, amphibians, animals)"	B5L172	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases	"Wang X, Lai R."	Odorrana grahmi antimicrobial peptide cDNA sequences.
DRAMP01714	MFTMKKSLLLLFFLGTINLSFCQEETNAEEERRDEEVAKMEEIKRGLLSGPRCGEESTMWT	61	"OGF2 antimicrobial peptide (Frogs, amphibians, animals)"	B5L190	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases	"Wang X, Lai R."	Odorrana grahmi antimicrobial peptide cDNA sequences.
DRAMP01715	MFTLKKPLLLLFFLGTINLSLCQDETNAEEERRDEEVVKMEEIKRGLLSGILGAGKHIVCGLTGCAKA	68	"OGG1 antimicrobial peptide (Frogs, amphibians, animals)"	B5L183	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases	"Wang X, Lai R."	Odorrana grahmi antimicrobial peptide cDNA sequences.
DRAMP01716	MFTLKKSLLLLFFLGTINLSLCQDVTNAEEERRDEEVAKMEEIKRGLLRPPRCGEAYSMWT	61	"OGF1 antimicrobial peptide (Frogs, amphibians, animals)"	B5L180	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases	"Wang X, Lai R."	Odorrana grahmi antimicrobial peptide cDNA sequences.
DRAMP02819	GLLKRIKTLL	10	"Anoplin (Insects, arthropods, invertebrates, animals)"	P0C005	Not found	Not found	Anoplius samariensis (Solitary wasp)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	The peptide adopts a random coil structure in water and tends to fold into an 	"2MJQ,2MJR,2MJS,2MJT"	"[Ref.29614317]Function: Antimicrobial activity against the Gram-positive, Gram-negative bacteria and fungi.##[Ref.25316570]Function: Exhibits potent activity in stimulating degranulation from rat peritoneal mast cells but not from RBL-2H3 cells. Exhibits broad-spectrum antimicrobial activity against both Gram-negative bacteriapositive and Gram-negative bacterianegative bacteria. Has no hemolytic activity towards human erythrocytes."	"[Ref.29614317]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=26 ¦Ìg/mL);##Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=13 ¦Ìg/mL);##Fungi: Candida albicans ATCC 10231 (MIC=19.5 ¦Ìg/mL).##[Ref.25316570]Gram-positive bacteria : Staphylococcus aureus (MIC=64 ¦Ìg/ml), bacillus subtilis (MIC=32 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli (MIC=64 ¦Ìg/ml), Peudomonas eruginosa (MIC=32 ¦Ìg/ml).##[Ref.27862650]Gram-positive bacteria : Mycobacteria smegmatis mc2 155 (MIC=200 ¦Ìg/ml), Bacillus subtilis DELTA (MIC=300 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli DH5a (MIC=200 ¦Ìg/ml), Pseudomonas aeruginosa PAO (MIC=100 ¦Ìg/ml), Zymomonas mobilis 10988 (MIC=40 ¦Ìg/ml);##Fungi : Candida parapsilosis (MIC=15 ¦Ìg/ml)"	"[Ref.25316570] 1% hemolysis at 12.5 ¦Ìg/ml , 2% hemolysis at 25 ¦Ìg/ml , 1% hemolysis at 50 ¦Ìg/ml , 1.5% hemolysis at 100 ¦Ìg/ml , 1.5% hemolysis at 200 ¦Ìg/ml against mice red blood cells.##[Ref.27862650]3% hemolysis at  100¦Ìg/ml , 6% hemolysis at 200¦Ìg/ml , 10% hemolysis at 300¦Ìg/ml , 12% hemolysis at 500¦Ìg/ml against human red blood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	29614317##25316570#27862650	Peptides. 2018 Jun;104:7-14.##J Pept Sci.?2014 Dec;20(12):945-51. doi: 10.1002/psc.2705.##J Pept Sci.?2016 Nov;22(11-12):731-736. doi: 10.1002/psc.2939.	"Salas RL, Garcia JKDL, Miranda ACR, Rivera WL, Nellas RB, Sabido PMG.##Yang Wang, Jianbo Chen, Xin Zheng, Xiaoli Yang, Panpan Ma,Ying Cai,Bangzhi Zhangb,and Yuan Chen##Kostas Chionis, Dimitrios Krikorian, Anna-Irini Koukkou, Maria Sakarellos-Daitsiotis and Eugenia Panou-Pomonis"	Effects of truncation of the peptide chain on the secondary structure and bioactivities of palmitoylated anoplin.##Design of novel analogues of short antimicrobial peptide anoplin with improved antimicrobial activity##Synthesis and biological activity of lipophilic analogs of the cationic antimicrobial active peptide anoplin
DRAMP02242	GLMDVFKGAAKNLLASALDKIRCKVTKC	28	"Ranatuerin-2PRa (frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pirica (Hokkaido frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: activity against reference strains of Gram-negative (Escherichia coli, Pseudomonas aeruginosa, Enterobacter cloacae, Klebsiella pneumoniae) and Gram-positive (Staphlococcus aureus) bacteria but displayed relatively low hemolytic activity. "	[Ref.15003829] Gram-negative bacterium: Escherichia coli(MIC=13¦ÌM);## Gram-positive bacterium: Staphylococcus aureus(MIC>100¦ÌM);## Yeast: Candida albicans(MIC=100¦ÌM)	[Ref.15003829] HC50=150¦ÌM against human erythrocytes	Cyclic	Free	Cyclization (Cys23 and Cys28)	Disulfide bond between Cys23 and Cys28.	L	No cytotoxicity information found	Not found	15003829	Regul Pept. 2004 May 15;118(3):135-141.	"Conlon JM, Sonnevend A, Patel M, Al-Dhaheri K, Nielsen PF, Kolodziejek J, Nowotny N, Iwamuro S, P"	"A family of brevinin-2 peptides with potent activity against Pseudomonas aeruginosa from the skin of the Hokkaido frog, Rana pirica."
DRAMP01772	FLPLIGKILGTILGK	15	"Temporin-1Ob (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana ornativentris (Japanese mountain brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17147973	Peptides. 2007 Mar;28(3):524-532.	"Ohnuma A, Conlon JM, Yamaguchi K, Kawasaki H, Coquet L, Leprince J, Jouenne T, Vaudry H, Iwamuro S."	Antimicrobial peptides from the skin of the Japanese mountain brown frog Rana ornativentris: evidence for polymorphism among preprotemporin mRNAs.
DRAMP01800	ILPILGNLLNSLL	13	"Temporin-1PRb (Temporin 1PRb; Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pirica (Hokkaido frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Staphylococcus aureus.##Yeast: Candida albicans (MIC>100 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15003829	Regul. Pept 2004; 118: 135-141.	Conlon JM et al Pal T.	"A family of brevinin-2 peptides with potent activity against Pseudomonas aeruginosa from the skin of the Hokkaido frog, Rana pirica."
DRAMP01387	GLLSGILGAGKHIVCGLSGPCQSLNRKSSDVEYHLAKC	38	"Odorranain-P2a (OdP2a; Frogs, amphibians, animals)"	A6MBR1	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	Function: Odorranain-P2a exhibites antimicrobial activities against all of the tested microbes including Gram-positive and Gram-negative bacteria and fungi. Has no hemolytic activity against red cell.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=6.25 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.12 ¦Ìg/ml), Bacillus subtilis (MIC=12.5 ¦Ìg/ml).##Yeast: Candida albicans (MIC=3.12 ¦Ìg/ml)."	[Ref:17272268]Non-hemolytic activity against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP01825	HFLGTLVNLAKKIL	14	"Temporin-1DRa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana aurora draytonii (California red-legged frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16307827	Peptides. 2006 Jun;27(6):1305-1312.	"Conlon JM, Al-Ghafari N, Coquet L, Leprince J, Jouenne T, Vaudry H, Davidson C."	"Evidence from peptidomic analysis of skin secretions that the red-legged frogs, Rana aurora draytonii and Rana aurora aurora, are distinct species."
DRAMP01126	ILGPVISKIGGVLGGLLKNL	20	"Maximin-H4 (Toads, amphibians, animals)"	"P83084, Q58T61, Q58T60"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. Shows strong hemolytic activity. "	"[Ref.11835991] Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=12 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=6 ¦Ìg/ml), Bacillus pyocyaneus CMCCB 1010 (MIC=12 ¦Ìg/ml).##Yeast: Candida albicans ATCC 2002 (MIC=6 ¦Ìg/ml)."	[Ref:11835991]90¨C100% hemolytic activity at 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-9.##Peptides. 2002 Mar;23(3):427-435.	"Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01125	ILGPVLGLVGNALGGLIKKI	20	"Maximin-H3 (Toads, amphibians, animals)"	"P83083, Q58T42, Q58T44, Q58T45, Q58T52, Q58T55, Q58T62, Q58T68, Q58T70"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. Shows strong hemolytic activity."	"[Ref.11835991] Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=20 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=10 ¦Ìg/ml), Bacillus pyocyaneus CMCCB 1010 (MIC=20 ¦Ìg/ml);##Fungi: Candida albicans ATCC 2002 (MIC=5 ¦Ìg/ml)."	[Ref:11835991]90¨C100% hemolytic activity at 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-9.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01871	FLPIIASVAAKLIPSIVCRITKKC	24	"Brevinin-1SPc (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Rana septentrionalis (mink frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Function: Has inhibitory activity towards reference strains of bacteria and an opportunistic yeast pathogen. Also has hemolytic activity against human erythrocytes.	No MICs found in DRAMP database	[Ref.15556063]HC50=3 ?M against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15556063	Comp Biochem Physiol C Toxicol Pharmacol. 2004 Oct;139(1-3):31-38.	"Bevier CR, Sonnevend A, Kolodziejek J, Nowotny N, Nielsen PF, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis).
DRAMP01901	GILDKLKEFGISAARGVAQSLLNTASCKLAKTC	33	"Brevinin-2CG1 (Frogs, amphibians, animals)"	No entry found	Not found	Not found	Amolops chunganensis	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Primarily active against Gram-positive bacteria. Also highly active against Gram-negative P. faecalis X29 and S. rubidaea.	"Gram-negative bacteria: P. faecalis X29, S. rubidaea."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22951323	Peptides. 2012 Nov;38(1):41-53.	"Yang X, Xia J, Yu Z, Hu Y, Li F, Meng H, Yang S, Liu J, Wang H."	Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis.
DRAMP01917	FFPNVASVPGQVLKKIFCAISKKC	24	"Brevinin-1PLa (Frogs, amphibians, animals)"	B6CPR5	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana palustris (Pickerel frog)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Inhibit the growth of Batrachochytrium dendrobatidis (Bd) (MIC=50 ?M), a fungus that might have played a role in killing many frogs."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18799711##11087945	Mol Biol Evol. 2008 Dec;25(12):2669-2680.##Biochim Biophys Acta. 2000 Nov 30;1543(1):95-105.	"Tennessen JA, Blouin MS.##Basir YJ, Knoop FC, Dulka J, Conlon JM."	"Balancing selection at a frog antimicrobial peptide locus: fluctuating immune effector alleles? ##Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris."
DRAMP01946	GLFNVFKGLKTAGKHVAGSLLNQLKCKVSGGC	32	"Brevinin-20a (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana Ornativentris (Japanese mountain brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11892844	J Pept Res. 2001 Nov;58(5):349-356.	Kim JB et al Conlon JM.	"Antimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris."
DRAMP01947	GIFNVFKGALKTAGKHVAGSLLNQLKCKVSGEC	33	"Brevinin-20b (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana Ornativentris (Japanese mountain brown frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11892844	J Pept Res. 2001 Nov;58(5):349-356.	Kim JB et al Conlon JM.	"Antimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris."
DRAMP01960	FLPILASLAAKFGPKLFCLVTKKC	24	"Brevinin-1BYa (Frogs, amphibians, animals)"	P84111	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana boylii (Foothill yellow-legged frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has hemolytic activity.	[Ref.14531844]Gram-positive bacterium:?Staphylococcus aureus(MIC=2 ?M);##Gram-negative bacterium:?Escherichia coli(MIC=17 ?M);##Yeast:?Candida albicans(MIC=3 ?M)	[Ref.14531844]HC50=4 ?M against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14531844	J Pept Res. 2003 Nov;62(5):207-213.	"Conlon JM, Sonnevend A, Patel M, Davidson C, Nielsen PF, P??l T, Rollins-Smith LA."	Isolation of peptides of the brevinin-1 family with potent candidacidal activity from the skin secretions of the frog Rana boylii.
DRAMP01961	FLPILASLAAKLGPKLFCLVTKKC	24	"Brevinin-1BYb (Frogs, amphibians, animals)"	P84112	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana boylii (Foothill yellow-legged frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has hemolytic activity.	[Ref.14531844]Gram-positive bacterium:?Staphylococcus aureus(MIC=4 ?M);##Gram-negative bacterium:?Escherichia coli(MIC=16 ?M);##Yeast:?Candida albicans(MIC=16 ?M).	[Ref.14531844]HC50=4 ?M against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14531844	J Pept Res. 2003 Nov;62(5):207-213.	"Conlon JM, Sonnevend A, Patel M, Davidson C, Nielsen PF, P??l T, Rollins-Smith LA."	Isolation of peptides of the brevinin-1 family with potent candidacidal activity from the skin secretions of the frog Rana boylii.
DRAMP01962	FLPILASLAATLGPKLLCLITKKC	24	"Brevinin-1BYc (Frogs, amphibians, animals)"	P84113	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana boylii (Foothill yellow-legged frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus.##Yeast: Candida albicans (weak activity).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14531844	J Pept Res. 2003 Nov;62(5):207-213.	"Conlon JM, Sonnevend A, Patel M, Davidson C, Nielsen PF, P??l T, Rollins-Smith LA."	Isolation of peptides of the brevinin-3 family with potent candidacidal activity from the skin secretions of the frog Rana boylii.
DRAMP01964	FLPIIAGVAAKVLPKIFCAISKKC	24	"Brevinin-1BLb (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Lithobates blairi (leopard frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19254736	Toxicon. 2009 Jun;53(7-8):699-705.	"Conlon JM, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis."
DRAMP01966	FLPVIAGVAANFLPKLFCAISKKC	24	"Brevinin-1Ya (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Lithobates yavapaiensis (North America leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	[Ref.19254736] Gram-positive bacteria : Staphylococcus aureus(MIC=3 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=50 ¦ÌM);##Fungi : Candida albicans(MIC=12 ¦ÌM)	[Ref.19254736] LC50=18 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19254736	Toxicon. 2009 Jun;53(7-8):699-705. doi: 10.1016/j.toxicon.2009.02.018.	"Conlon JM, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis."
DRAMP01967	FLPIIAGAAAKVVQKIFCAISKKC	24	"Brevinin-1Yb (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Lithobates yavapaiensis (North America leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	[Ref.19254736] Gram-positive bacteria : Staphylococcus aureus(MIC=3 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=25 ¦ÌM);##Fungi : Candida albicans(MIC=3 ¦ÌM)	[Ref.19254736] LC50=16 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19254736	Toxicon. 2009 Jun;53(7-8):699-705. doi: 10.1016/j.toxicon.2009.02.018.	"Conlon JM, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, King JD."	"Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis."
DRAMP01972	FLPLLPSALPSFLCLVFKKC	20	"Brevinin-1ZHc (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana zhenhaiensis (Chinese brown frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22943778	Zoolog Sci. 2012 Sep;29(9):553-558.	"Xu B, Che H, Kang L, Zheng S, Mu S, Wan F."	"Molecular Cloning and Functional Characterization of Novel Antimicrobial Peptides from the Skin of Brown Frog, Rana zhenhaiensis."
DRAMP01973	FLPLLLSALPSFSCLVFKKC	20	"Brevinin-1ZHd (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana zhenhaiensis (Chinese brown frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22943778	Zoolog Sci. 2012 Sep;29(9):553-558.	"Xu B, Che H, Kang L, Zheng S, Mu S, Wan F."	"Molecular Cloning and Functional Characterization of Novel Antimicrobial Peptides from the Skin of Brown Frog, Rana zhenhaiensis."
DRAMP01985	GLWDTIKQAGKKIFLSVLDKIRCKVAGGC	29	"Brevinin-2HS1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Huia schmackeri (Chinese piebald odorous frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Not found	Not found	None	"Function: Antimicrobial peptide homologs.
Tissue specificity: Expressed by the skin glands."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18423796	Peptides. 2008 Aug;29(8):1456-1460.	"Quan Z, Zhou M, Chen W, Chen T, Walker B, Shaw C."	Novel brevinins from Chinese piebald odorous frog (Huia schmackeri) skin deduced from cloned biosynthetic precursors.
DRAMP01988	FFGTALKIAANVLPTAICKILKKC	24	"Brevinin-1LTa (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Hylarana latouchii (Chinese frog fauna)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Tissue specificity: Expressed by the skin glands.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrance	19022312	Peptides. 2009 Feb;30(2):273-282.	"Wang H, Lu Y, Zhang X, Hu Y, Yu H, Liu J, Sun J."	"The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae)."
DRAMP01989	FFGTALKIAANILPTAICKILKKC	24	"Brevinin-1LTb (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Hylarana latouchii (Chinese frog fauna)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	"This peptide differs from Brevinin-1LTa by only one residue (I vs. V). This conservative change allows to predict that this peptide has all the activities of Brevinin-1LTa.
Tissue specificity: Expressed by the skin glands."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrance	19022312	Peptides. 2009 Feb;30(2):273-282.	"Wang H, Lu Y, Zhang X, Hu Y, Yu H, Liu J, Sun J."	"The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae)."
DRAMP02087	FLPVLAGLTPSIVPKLVCLLTKKC	24	"Brevinin-1PRb (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pretiosa (North oregon spotted frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	The MIC of Ranatuerin-2PRe is >50 ?M.	No MICs found in DRAMP database	[Ref.21295070] LC50=80¦ÌM against human erythrocytes.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	21295070	Dev Comp Immunol. 2011 Jun;35(6):644-649. 	"Conlon JM, Mechkarska M, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, Hayes MP, Padgett-Flohr G."	Host defense peptides in skin secretions of the Oregon spotted frog Rana pretiosa: implications for species resistance to chytridiomycosis.
DRAMP02088	FFPMLAGVAARVVPKVICLITKKC	24	"Brevinin-1PRc (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pretiosa (North oregon spotted frog)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	21295070	Dev Comp Immunol. 2011 Jun;35(6):644-649. 	"Conlon JM, Mechkarska M, Ahmed E, Coquet L, Jouenne T, Leprince J, Vaudry H, Hayes MP, Padgett-Flohr G."	Host defense peptides in skin secretions of the Oregon spotted frog Rana pretiosa: implications for species resistance to chytridiomycosis.
DRAMP01124	ILGPVLSMVGSALGGLIKKI	20	"Maximin-H2 (Toads, amphibians, animals)"	P83082	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi.Shows strong hemolytic activity. "	"[Ref.11835991] Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=20 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=2 ¦Ìg/ml), Bacillus pyocyaneus CMCCB 1010 (MIC=4 ¦Ìg/ml);##Fungi: Candida albicans ATCC 2002 (MIC=2 ¦Ìg/ml)."	[Ref:11835991]90¨C100% hemolytic activity at 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-9.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01123	ILGPVISTIGGVLGGLLKNL	20	"Maximin-H1 (Toads, amphibians, animals)"	"P83080, P83081, Q58T74, Q58T41"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. Shows strong hemolytic activity. "	"[Ref.11835991] Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=9 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=4.5 ¦Ìg/ml), Bacillus pyocyaneus CMCCB 1010 (MIC=9 ¦Ìg/ml).##Yeast: Candida albicans ATCC 2002 (MIC=4.5 ¦Ìg/ml)."	[Ref:11835991]90¨C100% hemolytic activity at 50 ¦Ìg/ml against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-9.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01111	SIGAKILGGVKTFFKGALKELASTYLQ	27	"Maximin-5 (Toads, amphibians, animals)"	"P83084, Q58T60, Q58T61"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral, Anti-cancer"	Protein level	Not found	Maximins are linear cationic peptides and easy to form membrane pore and they may induce a detergent-type disruption of sperm membrane like in the case of magainins.	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. Has little hemolytic activity. No amidation at the C-terminus.
Tissue specificity: Expressed by the skin glands."	"[Ref.11835991] Gram-negative bacterium: Klebsiella pneumoniae (MIC=3.6 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=3.6 ¦Ìg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=7.2 ¦Ìg/ml), Bacillus megatherium (MIC=12 ¦Ìg/ml), Bacillus dysenteriae (MIC=12 ¦Ìg/ml).##Fungi: Candida albicans ATCC 2002 (MIC=1.2 ¦Ìg/ml), Aspergillus flavus IFFI 4015 (MIC=12 ¦Ìg/ml), Penicillium uticale IFFI 2001 (MIC=12 ¦Ìg/ml);##Virus: HIV-1 (IC50=34.4 ¦Ìg/ml, EC50=39.8 ¦Ìg/ml);##Cancer cell lines: C8166 (IC50=34.4 ¦Ìg/ml)."	[Ref:11835991]Little hemolytic activity at 50 ¦Ìg/ml against red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-9.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01110	GIGGVLLSAGKAALKGLAKVLAEKYAN	27	"Maximin-4 (Toads, amphibians, animals)"	"P83083, Q58T42, Q58T44, Q58T52, Q58T62, Q58T77, Q58T79"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral, Anti-cancer"	Protein level	Not found	Maximins are linear cationic peptides and easy to form membrane pore and they may induce a detergent-type disruption of sperm membrane like in the case of magainins.	2MHW resolved by NMR	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. Has little hemolytic activity. Possess a significant cytotoxicity against tumor cell lines. Possess a significant anti-HIV activity. High spermicidal activity."	"[Ref.11835991] Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2.7 ?g/ml), Klebsiella pneumoniae (MIC=15 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=2.7 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=2.7 ?g/ml), Bacillus megatherium (MIC=1.5 ?g/ml), Bacillus dysenteriae (MIC=2.7 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=15 ?g/ml);##Virus: HIV-1 (IC50=24.2 ?g/ml, EC50=21.9 ?g/ml);##Cancer cell lines: C8166 (IC50=24.2 ?g/ml), Molt-4 (IC50=35.4 ?g/ml)."	[Ref:11835991]Little hemolytic activity at 50 ¦Ìg/ml against red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-9.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP01109	GIGGKILSGLKTALKGAAKELASTYLH	27	"Maximin-3 (Toads, amphibians, animals)"	"P83082, Q58T40, Q58T43, Q58T46, Q58T48, Q58T64, Q58T65, Q58T68, Q58T69"	Belongs to the bombinin family	Not found	Bombina maxima (Giant fire-bellied toad) (Chinese red belly toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral, Anti-cancer"	Protein level	Not found	Maximins are linear cationic peptides and easy to form membrane pore and they may induce a detergent-type disruption of sperm membrane like in the case of magainins.	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. Has little hemolytic activity. Possess a significant cytotoxicity against tumor cell lines. Possess a significant anti-HIV activity. High spermicidal activity. No amidation at the C-terminus.
Toxic dose: LD50 is 4.3 mg/kg by intraperitoneal injection into mice.
Tissue specificity: Expressed by the skin glands."	"[Ref.11835991] Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=0.9 ?g/ml), Klebsiella pneumoniae (MIC=3.1 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=3.1 ?g/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=1.5 ?g/ml), Bacillus megatherium (MIC=0.9 ?g/ml), Bacillus dysenteriae (MIC=0.9 ?g/ml);##Yeast: Candida albicans ATCC 2002 (MIC=15 ?g/ml);##Virus: HIV-1 (IC50=11.4 ?g/ml, EC50=1.5 ?g/ml);##Cancer cell lines: C8166 (IC50=11.4 ?g/ml), Molt-4 (IC50=25.2 ?g/ml), BIU-87 (IC50=28 ?g/ml), T24 (IC50=18 ?g/ml)."	[Ref:11835991]Little hemolytic activity at 50 ¦Ìg/ml against red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	15770703##11835991	Eur J Immunol. 2005 Apr;35(4):1220-9.##Peptides. 2002 Mar;23(3):427-435.	"Lee WH, Li Y, Lai R, Li S, Zhang Y, Wang W.##Lai R, Zheng YT, Shen JH, Liu GJ, Liu H, Lee WH, Tang SZ, Zhang Y."	Variety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification.##Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
DRAMP02100	FLPIIASVAAKVFPKIFCAISKKC	24	"Brevinin-1Pe (Frogs, amphibians, animals)"	P82845	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pipiens (Northern leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP02134	GMATKAGTALGKVAKAVIGAAL	22	"Antimicrobial peptide 5 (XT-5; PGLa-like peptide; Frogs, amphibians, animals)"	P84385	Not found	Not found	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacterium S. aureus, Gram-negative bacterium E.coli and yeast C. albicans. Has strong hemolytic activity against human red blood cells.
Tissue specificity: Skin."	[Ref.11738090]Gram-positive bacteria: Staphylococcus aureus (MIC>100 ?M);##Gram-negative bacteria: Escherichia coli (MIC>100 ?M);##Fungi: Candida albicans (MIC>100 ?M)	[Ref.11738090]HC50>150 ¦ÌM against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	11738090	Biochim Biophys Acta. 2001 Nov 26;1550(1):81-89.	"Ali MF, Soto A, Knoop FC, Conlon JM."	"Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae)."
DRAMP02086	FLPVLTGLTPSIVPKLVCLLTKKC	24	"Brevinin-1PRa (frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pretiosa (North oregon spotted frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: activity against reference strains of Gram-negative (Escherichia coli, Pseudomonas aeruginosa, Enterobacter cloacae, Klebsiella pneumoniae) and Gram-positive (Staphlococcus aureus) bacteria but displayed relatively low hemolytic activity. "	[Ref.15003829] Gram-negative bacterium: Escherichia coli(MIC>100¦ÌM);## Gram-positive bacterium: Staphylococcus aureus(MIC=13¦ÌM);## Yeast: Candida albicans(MIC=100¦ÌM).[Ref.21295070] Gram-negative bacterium: Escherichia coli(MIC>100¦ÌM);## Gram-positive bacterium: Staphylococcus aureus(MIC=50¦ÌM);## Yeast: Candida albicans(MIC=100¦ÌM).	[Ref.15003829] HC50=7¦ÌM against human erythrocytes.##[Ref.21295070] LC50= 150¦ÌM against human erythrocytes.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	15003829##21295070	Regul Pept. 2004 May 15;118(3):135-141.## Dev Comp Immunol. 2011 Jun;35(6):644-649. 	"Conlon JM, Sonnevend A, Patel M, Al-Dhaheri K, Nielsen PF, Kolodziejek J, Nowotny N, Iwamuro S, P"	"A family of brevinin-2 peptides with potent activity against Pseudomonas aeruginosa from the skin of the Hokkaido frog, Rana pirica.## Host defense peptides in skin secretions of the Oregon spotted frog Rana pretiosa: implications for species resistance to chytridiomycosis."
DRAMP01384	DEKGPKWKR	9	"Odorranain-N1 (OdN1; Frogs, amphibians, animals)"	A6MBP9	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	Function: Odorranain-N1 appears to be narrowly antifungal with low potency against Candida albicans.	[Ref.17272268] Yeast: Candida albicans (MIC=35.20 ¦Ìg/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP02284	GLNTLKKVFQGLHEAIKLINNHVQ	24	"Pseudin-1 (Pseudin 1; Frogs, amphibians, animals)"	P83188	Not found	Not found	Pseudis paradoxa (Paradoxical frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Possesses antifungal activity against C. albicans and is also active against E. coli and S. aureus.
Tissue specificity: Expressed by the skin glands."	Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Staphylococcus aureus.##Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11689009	Biochem Biophys Res Commun. 2001 Nov 9;288(4):1001-1005.	"Olson L 3rd, Soto AM, Knoop FC, Conlon JM."	Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.
DRAMP02285	GLNALKKVFQGIHEAIKLINNHVQ	24	"Pseudin-2 (Pseudin 2; Frogs, amphibians, animals)"	P83189	Not found	Not found	Pseudis paradoxa (Paradoxical frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Possesses antifungal activity against C. albicans and is also active against E. coli and S. aureus. Has low hemolytic activity against human erythrocytes.
Tissue specificity: Expressed by the skin glands."	[Ref.11689009]Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Staphylococcus aureus;##Yeast: Candida albicans	[Ref.11689009]50% hemolysis of human erythrocytes is >300 ¦ÌM	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11689009	Biochem Biophys Res Commun. 2001 Nov 9;288(4):1001-1005.	"Olson L 4rd, Soto AM, Knoop FC, Conlon JM."	Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.
DRAMP02286	GINTLKKVIQGLHEVIKLVSNHE	23	"Pseudin-3 (Pseudin 3; Frogs, amphibians, animals)"	P83190	Not found	Not found	Pseudis paradoxa (Paradoxical frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Possesses antifungal activity against C. albicans and is also active against E. coli and S. aureus.
Tissue specificity: Expressed by the skin glands."	Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Staphylococcus aureus;##yeast Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11689009	Biochem Biophys Res Commun. 2001 Nov 9;288(4):1001-1005.	"Olson L 5rd, Soto AM, Knoop FC, Conlon JM."	Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.
DRAMP02287	GINTLKKVIQGLHEVIKLVSNHA	23	"Pseudin-4 (Pseudin 4; Frogs, amphibians, animals)"	P83191	Not found	Not found	Pseudis paradoxa (Paradoxical frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Possesses antifungal activity against C. albicans and is also active against E. coli and S. aureus.
Tissue specificity: Expressed by the skin glands."	Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Staphylococcus aureus;##yeast Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11689009	Biochem Biophys Res Commun. 2001 Nov 9;288(4):1001-1005.	"Olson L 6rd, Soto AM, Knoop FC, Conlon JM."	Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.
DRAMP01375	GLGGAKKNFIIAANKTAPQSVKKTFSCKLYNG	32	"Odorranain-E1 (OdE1; Frogs, amphibians, animals)"	A6MBK8	Not found	Not found	Odorrana grahami (Yunnanfu frog) (Rana grahami)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Odorranain-E1 adopts 100% turn structure in water solution.	None	Function: Odorranain-E1 exhibites antimicrobial activities against all of the tested microbes including Gram-positive and Gram-negative bacteria and fungi. Has no hemolytic activity against red cell.	"[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=9.37 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=4.68 ¦Ìg/ml), Bacillus subtilis (MIC=4.68 ¦Ìg/ml).##Yeast: Candida albicans (MIC=9.37 ¦Ìg/ml)."	[Ref:17272268]Non-hemolytic activity against rabbit red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17272268	Mol Cell Proteomics. 2007 May;6(5):882-894.	"Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J."	Anti-infection peptidomics of amphibian skin.
DRAMP02353	RSTEDIIKSISGGGFLNAMNA	21	"Pleurocidin-like peptide WFX (fish, chordates, animals; Predicted)"	Q7T053	Not found	ple6	Pseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Predicted	Not found	Not found	None	Function: Has antibacterial and antifungal activity.	"Gram-negative bacteria: Aeromonas salmonicida A449 field isolate (MIC>64 ?g/ml), A. salmonicida 97-4 field isolate (MIC>64 ?g/ml), Pseudomonas aeruginosa K799 (MIC>64 ?g/ml), Pseudomonas aeruginosa Z61 (MIC>64 ?g/ml), Escherichia coli (MIC>64 ?g/ml), Salmonella typhimurium 14028s (MIC>64 ?g/ml), S. typhimurium MS7953s (MIC>64 ?g/ml);##Gram-positive bacteria: Staphylococcus epidermidis (human clinical isolates) (MIC>64 ?g/ml), Staphylococcus aureus (MRSA) (MIC>64 ?g/ml).##Fungi: Candida albica (MIC>64 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12950255	Eur J Biochem. 2003 Sep;270(18):3720-3730.	"Douglas SE, Patrzykat A, Pytyck J, Gallant JW."	"Identification, structure and differential expression of novel pleurocidins clustered on the genome of the winter flounder, Pseudopleuronectes americanus (Walbaum)."
DRAMP02375	RQRVEELSKFSKKGAAARRRK	21	"Misgurin (weatherfish, chordates, animals)"	P81474	Not found	Not found	Misgurnus anguillicaudatus (Oriental weatherfish) (Oriental weatherloach)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Alpha helix 	Not found	None	Comment: No comments found on DRAMP database	"B.subtilus, Staphylococcus aureus, Streptococcus mutans, Streptococcus pneumoniae, Pseudomonas putida, Escherichia coli, Salmonella typhimurium, Serratia spps, Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisae."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9271200	FEBS Lett. 1997 Jul 14;411(2-3):173-178.	"Park CB, Lee JH, Park IY, Kim MS, Kim SC."	"A novel antimicrobial peptide from the loach, Misgurnus anguillicaudatus."
DRAMP02387	PDPAKTAPKKKSKKAVT	17	"Histone HIIb-3 (Antibacterial histone-like protein 3, HLP-3; catfishes, chordates, animals)"	P81904	Belongs to the histone H2B family	Not found	Ictalurus punctatus (Channel catfish)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."	"Aeromonas hydrophila, Saprolegnia spp."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9645227	Cell Mol Life Sci. 1998 May;54(5):467-475.	"Robinette D, Wada S, Arroll T, Levy MG, Miller WL, Noga EJ."	Antimicrobial activity in the skin of the channel catfish Ictalurus punctatus: characterization of broad-spectrum histone-like antimicrobial proteins.
DRAMP02388	PDPAKTAPKKGSKKAVTKXA	20	"Histone HIIb-1 (Antibacterial histone-like protein 1, HLP-1; catfishes, chordates, animals)"	P81903	Belongs to the histone H2B family	Not found	Ictalurus punctatus (Channel catfish)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. "	"Aeromonas hydrophila, vibrio alginolyticus, Escherichia coli D31, Saprolegnia spp."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9645227	Cell Mol Life Sci. 1998 May;54(5):467-475.	"Robinette D, Wada S, Arroll T, Levy MG, Miller WL, Noga EJ."	Antimicrobial activity in the skin of the channel catfish Ictalurus punctatus: characterization of broad-spectrum histone-like antimicrobial proteins.
DRAMP02392	GWFKKAWRKVKNAGRVLKGVGIHYGVGLIG	30	"Hematopoietic antimicrobial peptide-29 (MgCath29; hagfishes, chordates, animals)"	Q71MD5	Not found	CATH29	Myxine glutinosa (Atlantic hagfish)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15019197	Peptides. 2003 Nov;24(11):1655-1667.	"Uzzell T, Stolzenberg ED, Shinnar AE, Zasloff M."	Hagfish intestinal antimicrobial peptides are ancient cathelicidins.
DRAMP02245	GLFLDTLKGLAGKLLQGLKCIKAGCKP	27	"Ranatuerin-2Cb (Ranatuerin 2Cb; Frogs, amphibians, animals)"	P82879	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Rana clamitans (Green frog) (Lithobates clamitans)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. 
Tissue specificity: Expressed by the skin glands."	[Ref.10822101] Gram-positive bacterium: Staphylococcus aureus (MIC=40 ¦Ìg/ml);##Gram-negative bacterium: Escherichia coli (MIC=2 ¦Ìg/ml).##Yeast: Candida albicans (MIC=46 ¦Ìg/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10822101	Peptides. 2000 Apr;21(4):469-476.	"Halverson T, Basir YJ, Knoop FC, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin of the North American green frog Rana clamitans.
DRAMP02398	GPVGLLSSPGSLPPVGGAP	19	Antimicrobial peptide GP-19 (GP-19)	B3A0L2	Not found	Not found	Xenorhabdus budapestensis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: GP-19 displays broad-spectrum antimicrobial activity against the tested bacteria and fungi.	"Gram-positive bacteria: Bacillus subtilis (IZ=19.04¡À0.2 mm), Bacillus megaterium (IZ=7.3¡À0.28 mm), Prototheca wickerhamii (IZ=10.3¡À0.33 mm);##Gram-negative bacteria: Xanthomonas campestris pv. vesicatoria (IZ=16.47¡À0.35 mm), Pseudomonas solanacearum (IZ=10.75¡À0.41 mm).##fungi: Phytophthora capsici (CD=16.62¡À1.07 mm), Verticillium dahlia (EC50=17.54 ?g/ml), Fusarium graminearum (CD=12.04¡À0.87 mm), Fusarium omysporum (CD=21.64¡À0.4 mm).##NOTE: IZ = Inhibition Zone and CD = Colony diameter."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22497806	Peptides. 2012 Jun;35(2):253-260.	"Xiao Y, Meng F, Qiu D, Yang X."	Two novel antimicrobial peptides purified from the symbiotic bacteria Xenorhabdus budapestensis NMC-10.
DRAMP02399	EGPVGLADPDGPASAPLGAP	20	Antimicrobial peptide EP-20 (EP-20)	B3A0L3	Not found	Not found	Xenorhabdus budapestensis	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: EP-20 showes high inhibition against P. capsici but lower antibacterial activity.	"Fungi: Phytophthora capsici (EC50=3.14 ?g/ml), Verticillium dahlia (CD=19.32¡À1.31 mm), Fusarium graminearum (CD=12.45¡À1.6 mm), Fusarium oxysporum (CD=21.29¡À1.1 mm).##NOTE: CD = Colony diameter."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22497806	Peptides. 2012 Jun;35(2):253-260.	"Xiao Y, Meng F, Qiu D, Yang X."	Two novel antimicrobial peptides purified from the symbiotic bacteria Xenorhabdus budapestensis NMC-10.
DRAMP02404	CPAIQRCCQQLRNIQPPCRCCQ	22	Chitin-binding protein 3 (Mo-CBP3)	P86528	Not found	Not found	Moringa oleifera (Horseradish tree) (Moringa pterygosperma)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Chitin binding protein. Has antifungal activity against F. solani. Not toxic to mice. Acts as a flocculent.
PTM: Glycosylated; contains 2.5% carbohydrates.
Miscellaneous: On the 2D-gel the determined pI of this protein is: 10.8, its MW is: 14.34 kDa."	Fungi: Fusarium solani.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	PubMed ID is not available	"Thesis (2010), Federal University of Ceara, Brazil"	Gifoni J.M.	Isolation and biochemical characterization of a new thermostable antifungal chitin-binding protein from Moringa oleifera seeds.
DRAMP02405	QSERFEQQMQGQDFSHDERFLSQAA	25	Antifungal protein 1 (Pf-AFP1; Plants)	P84884	Belongs to the 2S seed storage albumins family	Not found	Passiflora edulis (Passion fruit)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Function: Has strong antifungal activity against T. harzianum, F. oxysporum and A. fumigatus. Lacks antifungal activity against R. solani, P. brasiliensis and C. albicans.
Tissue specificity: Expressed in seed (at protein level). Not detected in pulp, stems and leaves.
Developmental stage: Expressed in dormant seed."	"Fungi: Trichoderma harzianum (IC50=32 ?g/ml), Fusarium oxysporum (IC50=34 ?g/ml), Aspergillus fumigatus (IC50=40 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16766236	Biochim Biophys Acta. 2006 Jun;1764(6):1141-6.	"Pelegrini PB, Noronha EF, Muniz MA, Vasconcelos IM, Chiarello MD, Oliveira JT, Franco OL."	An antifungal peptide from passion fruit (Passiflora edulis) seeds with similarities to 2S albumin proteins.
DRAMP02408	PVSRQQCSQRIQGERFNQCRSQMQDGQLQSCCQELQNVEEQCQC	44	2S albumin (To-A1)	P86783	Belongs to the 2S seed storage albumins family	Not found	Taraxacum officinale (Common dandelion) (Leontodon taraxacum)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: This is a 2S seed storage protein. Has antifungal activity. Inhibits growth of H.sativum, V.albo-atrum and P. infestans.
Subunit structure: The sequence shown is the mature protein which consists of a small and a large chain linked by 2 disulfide bonds."	"Fungi: Helminthosporium sativum (IC50=62.5 ?g/ml), Pemphigus betae (IC50=62.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19594427	Protein Pept Lett. 2010 Apr;17(4):522-529.	"Odintsova TI, Rogozhin EA, Sklyar IV, Musolyamov AK, Kudryavtsev AM, Pukhalsky VA, Smirnov AN, Grishin EV, Egorov TA."	Antifungal activity of storage 2S albumins from seeds of the invasive weed dandelion Taraxacum officinale Wigg.
DRAMP02418	GFGCPLNQGACHNHCRSIGRRGGYCAGIIKQTCTCYRK	38	"Longicin (Ticks, Arthropods, animals)"	No entry found	Not found	Not found	Haemaphysalis longicornis (Tick)	"Antimicrobial, Antibacterial, Antifungal, Antiparasitic"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17485458	Infect Immun. 2007 Jul;75(7):3633-3640.	"Tsuji N, Battsetseg B, Boldbaatar D, Miyoshi T, Xuan X, Oliver JH Jr, Fujisaki K."	Babesial vector tick defensin against Babesia sp. parasites.
DRAMP02431	HHVELCKKNDAELKEALTCITSKLPAALGCNDKSCVFEKLCKEGDLDEALKKHFTEAEVQTLHTTATDCDHSHGHEHSHGHEHGHGHH	88	"Antimicrobial peptide microplusin (Ticks, Arthropods, animals)"	B7PCF6	Not found	Not found	Ixodes scapularis (Black-legged tick) (Deer tick)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Has bacteriostatic activity against Gram-positive bacteria, but not against Gram-negative bacteria. Has fungistatic activity against some but not all fungi. Binds and sequesters copper and iron ions. Copper-chelating is crucial for antimicrobial activity against M. luteus.
PTM: Contains three disulfide bonds 6-41; 19-69; 30-35."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases	"Caler E, Hannick L I, Bidwell S. et al."	Annotation of Ixodes scapularis.
DRAMP02435	LSKFGGECSLKHNTCTYLKGGKNHVVNCGSAANKKCKSDRHHCEYDEHHKRVDCQTPV	58	Antifungal protein (PgAFP; Cys-rich)	"D0EXD3, B6GXZ8"	Not found	afp	Penicillium chrysogenum (Penicillium notatum)	"Antimicrobial, Antibacterial, Antifungal, Antiparasitic"	Protein level	Not found	Not found	None	"Function: Has strong antifungal activity against the molds Polytrichum commune Pc332, Penicillium echinulatum Pe321, and Aspergillus niger An261.
PTM: Contains three disulfide bonds (By similarity)."	"Fungi: Polytrichum commune Pc332, Penicillium echinulatum Pe321, Aspergillus niger An261."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19914321##19683356	Peptides. 2010 Apr;31(4):541-547.##Int J Food Microbiol. 2009 Sep 30;135(1):39-46.	"Rodr¨ªguez-Mart¨ªn A, Acosta R, Liddell S, N¨²?ez F, Benito MJ, Asensio MA.##Acosta R, Rodr¨ªguez-Mart¨ªn A, Mart¨ªn A, N¨²?ez F, Asensio MA."	Characterization of the novel antifungal protein PgAFP and the encoding gene of Penicillium chrysogenum.##Selection of antifungal protein-producing molds from dry-cured meat products.
DRAMP02436	EQPGGDKVNLGYFTN	15	Chitinase	P84754	Belongs to the glycosyl hydrolase 18 family Chitinase (class	Not found	Streptomyces violaceus (Streptomyces venezuelae)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity.
Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.
Enzyme regulation: Inhibited by divalent metal ions. Maximum inhibition observed with Ca2+ while the least inhibition was observed with Fe2+. Inhibited by high concentrations of GlcNAc.
Biophysicochemical properties: pH dependence (Optimum pH is 6-8. There is a 37.7% decrease in activity at pH 5 and a 39.8% decrease in activity at pH 9); Temperature dependence (Optimum temperature is 35 degrees Celsius)."	"Fungi: Aspergillus niger, Alternaria alternata, Hordeum sativum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	PubMed ID is not available##16972135	"Thesis (2005), Visva Bharati (Central University), India.##Curr Microbiol. 2006 Oct;53(4):265-269."	"Mukherjee G.##Mukherjee G, Sen SK."	"Extracellular production of chitinase by Streptomyces venezuelae.##Purification, characterization, and antifungal activity of chitinase from Streptomyces venezuelae P(10)."
DRAMP02448	ASGGTVGXYGAWMRSXSLVSXSTITTFS	28	Antibacterial protein LC3 (Antibacterial protein LCIII)	Q9R5C6	Not found	Not found	Bacillus subtilis	"Antimicrobial, Antibacterial, Antifungal, Antiparasitic"	Protein level	Not found	Not found	None	"Function: Has antibacterial activity.
Miscellaneous: On a 2D-GEL the determined pI of this protein is: 9.12."	X. campestris strain G and P. solacearum PO1.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1295599	Chin J Biotechnol. 1992;8(3):187-193.	"Liu J, Li Z, Pan N, Chen Z."	Purification and partial characterization of an antibacterial protein LCIII.
DRAMP02461	AHDGNPLEECFREDDEEFFLEIAKNGLTATSNPKRVVIV	39	"L-amino-acid oxidase (BmarLAAO; LAAO; LAO; snakes, reptils, animals)"	P0CJ40	Belongs to the flavin monoamine oxidase family (FIG1 subfamily)	Not found	Bothrops marajoensis (Marajo lancehead)	"Antimicrobial, Antibacterial, Antifungal, Antiparasitic"	Protein level	Not found	Not found	None	"Function: Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme. Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, and antiparasitic activities, as well as regulation of platelet aggregation. Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation. These different effects are probably due to different experimental conditions By similarity. In addition, this protein inhibits dose-dependently the growth of Gram-positive, Gram-negative bacteria and yeast, probably by the generation of hydrogen peroxide.
Tissue specificity: Expressed by the venom gland.
Miscellaneous: Has parasiticidal activities against leishmania, as a result of enzyme-catalyzed hydrogen peroxide production."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19944711	Toxicon. 2010 Apr 1;55(4):795-804.	"Costa Torres AF, Dantas RT, Toyama MH, Diz Filho E, Zara FJ, Rodrigues de Queiroz MG, Pinto Nogueira NA, Rosa de Oliveira M, de Oliveira Toyama D, Monteiro HS, Martins AM."	Antibacterial and antiparasitic effects of Bothrops marajoensis venom and its fractions: phospholipase A2 and L-amino acid oxidase.
DRAMP02483	KFFKKLKNSVKKRAKKFFKKPKVIGVTFPF	30	"Cathelicidin-NA (Cathelicidin-related protein; Snakes, reptiles, animals)"	B6S2X0	Not found	Not found	Naja atra (Chinese cobra)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Alpha helix 	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacteria: Escherichia coli ATCC 25922, Escherichia coli ML-35P, Escherichia coli clinic strain, Pseudomonas aeruginosa ATCC 27853, Pseudomonas aeruginosa PA 01, Pseudomonas aeruginosa clinic strain, Enterobacter aerogenes clinic strain, Enterobacter cloacae clinic strain."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	18620012	Peptides. 2008 Oct;29(10):1685-91. 	"Zhao H, Gan TX, Liu XD, Jin Y, Lee WH, Shen JH, Zhang Y."	Identification and characterization of novel reptile cathelicidins from elapid snakes.
DRAMP02511	YKQCHKKGGHCFPKEKICLPPSSDFGKMDCRWRWKCCKKGSG	42	"Crotamine (defensin-like toxin; Snakes, reptiles, animals)"	Q9PWF3	Belongs to the crotamine-myotoxin family	CRO2	Crotalus durissus terrificus (South American rattlesnake)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Cytotoxic, Antifungal"	Protein level	Combine helix and strand structure	"Crotamine contains an alpha-helix with residues 1-7 and a two-stranded anti-parallel beta-sheet with residues 9-13 and 34-38 as the only regular secondary structures. These are connected with each other and the remainder of the polypeptide chain by the three disulfide bonds, which also form part of a central hydrophobic core (Ref.2)."	1Z99 resolved by NMR.	"Function: It exhibits antimicrobial activities, hind limb paralysis, and severe muscle necrosis by a non-enzymatic mechanism. As a cell-penetrating peptide, crotamine has high specificity for actively proliferating cells, and interacts inside the cell with subcellular and subnuclear structures, like vesicular compartments, chromosomes and centrioles. Crotamine has marked activity against the eukaryotic pathogen Candida albicans at pH 7.5 or 5.5.
Tissue specificity: Expressed by the venom gland.
Toxic dose: LD50 is 1.5 mg/kg by intravenous injection. LD50 is 32.8 mg/kg by intraperitoneal injection into mice.(Ref.3)(Ref.4)
Pharmaceutical use: Has high potential for use as an anticancer agent. In vivo treatment with this protein significantly delays tumor implantation, inhibits tumor growth and prolongs the lifespan of the mice with melanoma tumors. It has also potent and specific toxicity against tumor cell lines of aggressive mouse and human tumors, but low cytotoxicity against non-tumoral cell lines. In addition, this protein can act as a carrier capable of delivering DNA into replicating cells with low cytotoxicity against normal proliferative cells.(Ref.5)(Ref.6)
Miscellaneous: Has no hemolytic activity ."	[Swiss_Prot Entry Q9PWF3]Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacteria: Escherichia coli;##Yeast: Candida albicans	[Ref.210622]Non-hemolytic activity	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Eukaryotic ion channels	19706485##16185738##1176086##9839677##22142367##210622	Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14972-14977.##Toxicon. 2005 Dec 1;46(7):759-767.##Hoppe Seylers Z Physiol Chem. 1975 Feb;356(2):213-215.##Toxicon. 1998 Dec;36(12):1927-1937.##Mol Pharm. 2012 Feb 6	"Yount NY, Kupferwasser D, Spisni A, Dutz SM, Ramjan ZH, Sharma S, Waring AJ, Yeaman MR.##Fadel V, Bettendorff P, Herrmann T, de Azevedo WF Jr, Oliveira EB, Yamane T, W¨¹thrich K.##Laure CJ.##Mancin AC, Soares AM, Andri?o-Escarso SH, Fa?a VM, Greene LJ, Zuccolotto S, Pel¨¢ IR, Giglio JR.##Nascimento FD, Sancey L, Pereira A, Rome C, Oliveira V, Oliveira EB, Nader HB, Yamane T, Kerkis I, Tersariol IL, Coll JL, Hayashi MA.##Kerkis I, Silva "	"Selective reciprocity in antimicrobial activity versus cytotoxicity of hBD-2 and crotamine.##Automated NMR structure determination and disulfide bond identification of the myotoxin crotamine from Crotalus durissus terrificus.##The primary structure of crotamine (author's transl).##he analgesic activity of crotamine, a neurotoxin from Crotalus durissus terrificus (South American rattlesnake) venom: a biochemical and pharmacological study.##The natural cell-penetrating peptide crotamine targets tu"
DRAMP02521	KFFKKLKNSVKKRAKKFFKKPRVIGVSIPF	30	"Cathelicidin-OH (Cathelicidin-related protein; Snakes, reptiles, animals)"	B6S2X2	Belongs to the?cathelicidin family.	Not found	Ophiophagus hannah (King cobra) (Naja hannah)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram+, Antifungal"	Transcript level	Alpha helix 	Not found	2mwt resolved by NMR	"[Ref.22491685]Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans"	"[Ref.18620012]Gram-negative bacteria: Escherichia coli ATCC 25922, Escherichia coli ML-35P, Escherichia coli clinic strain, Pseudomonas aeruginosa ATCC 27853, Pseudomonas aeruginosa PA 01, Pseudomonas aeruginosa clinic strain, Enterobacter aerogenes clinic strain, Enterobacter cloacae clinic strain.##[Ref.22491685]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=3.125 ¦Ìg/ml), Staphylococcuss aureus ATCC 43300 MRSA (MIC=6.25 ¦Ìg/ml), Staphylococcuss aureus clinical strain 1 (MIC=3.125 ¦Ìg/ml), Staphylococcuss aureus clinical strain 2 (MIC=6.25 ¦Ìg/ml), Staphylococcuss aureus clinical strain 3 (MIC=6.25 ¦Ìg/ml), Enterococcus faecalis ATCC 29212 (MIC=25 ¦Ìg/ml) ;##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=6.25 ¦Ìg/ml), Escherichia coli ML-35p (MIC=3.125 ¦Ìg/ml), Escherichia coli clinical strain 1 (MIC=6.25 ¦Ìg/ml), Escherichia coli clinical strain 2 (MIC=3.125 ¦Ìg/ml), Escherichia coli clinical strain 3 (MIC=1.56 ¦Ìg/ml), Escherichia coli clinical strain 4 (MIC=12.5 ¦Ìg/ml), Escherichia coli clinical strain 5 (MIC=3.125 ¦Ìg/ml), Escherichia coli clinical strain 6 (MIC=3.125 ¦Ìg/ml), Enterobacter cloacae ATCC 13047 (MIC=25 ¦Ìg/ml), Enterobacter cloacae clinical strain (MIC=3.125 ¦Ìg/ml), Enterobacter aerogenes clinical strain (MIC=6.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=6.25 ¦Ìg/ml), Pseudomonas aeruginosa PA 01 (MIC=6.25 ¦Ìg/ml), Pseudomonas aeruginosa clinical strain 1 (MIC=12.5 ¦Ìg/ml), Pseudomonas aeruginosa clinical strain 2 (MIC=6.25 ¦Ìg/ml), Haemophilus influenzae ATCC 49247 (MIC=3.125 ¦Ìg/ml), Haemophilus influenzae ATCC 49766 (MIC=3.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883 (MIC=6.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MIC=3.125 ¦Ìg/ml) ;##Fungi : Candida albicans ATCC 2002 (MIC>200 ¦Ìg/ml), Candida albicans clinical strain (MIC>200 ¦Ìg/ml)"	"[Ref.22491685] 3% hemolysis at 100 ¦Ìg/ml , 5% hemolysis at 200 ¦Ìg/ml , 6% hemolysis at 300 ¦Ìg/ml , 7% hemolysis at 400 ¦Ìg/ml against human red blood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	18620012##22491685	Peptides. 2008 Oct;29(10):1685-91. ##Antimicrob Agents Chemother.?2012 Jun;56(6):3309-17. doi: 10.1128/AAC.06304-11.	"Zhao H, Gan TX, Liu XD, Jin Y, Lee WH, Shen JH, Zhang Y.##Sheng-An Li, Wen-Hui Lee, and Yun Zhang"	Identification and characterization of novel reptile cathelicidins from elapid snakes.##Efficacy of OH-CATH30 and Its Analogs against Drug-ResistantBacteria In Vitro and in Mouse Models
DRAMP02570	YRGGYTGPIPRPPPIGRPPLRLVVCACYRLSVSDARNCCIKFGSCCHLVK	50	"Penaeidin-1 (Pen-1; shrimps, Arthropods, animals)"	P81056	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Not found	Not found	None	"Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Tissue specificity: Higher expression in hemocytes and to a lesser extent in heart, testis, gills, intestine, lymphonoid organ and hepatopancreas. Traces in eyes and subcuticular epithelium. Not present in the brain.
Developmental stage: Expression decreases 3 hours after microbial challenge to return to control levels after 12 hours and slightly increases after 24 hours.
PTM: Contains three disulfide bonds 25-38; 27-45; 39-46."	"Gram-positive bacterium: Micrococcus luteus;##Gram-negative bacterium: Escherichia coli.##Fungi: Neurospora crassa, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	9353298##10639333	Biol Chem. 1997 Nov 7;272(45):28398-28406.##J Cell Sci. 2000 Feb;113 (Pt 3):461-469.	"Destoumieux D, Bulet P, Loew D, Van Dorsselaer A, Rodriguez J, Bach¨¨re E.##Destoumieux D, Mu?oz M, Cosseau C, Rodriguez J, Bulet P, Comps M, Bach¨¨re E."	"Penaeidins, a new family of antimicrobial peptides isolated from the shrimp Penaeus vannamei (Decapoda).##Penaeidins, antimicrobial peptides with chitin-binding activity, are produced and stored in shrimp granulocytes and released after microbial challenge."
DRAMP02571	YRGGYTGPIPRPPPIGRPPFRPVCNACYRLSVSDARNCCIKFGSCCHLVK	50	"Penaeidin-2a (Pen-2a; shrimps, Arthropods, animals)"	P81057	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Not found	Not found	None	"Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Tissue specificity: Higher expression in hemocytes and to a lesser extent in heart, testis, gills, intestine, lymphonoid organ and hepatopancreas. Traces in eyes and subcuticular epithelium. Not present in the brain.
Developmental stage: Expression decreases 3 hours after microbial challenge to return to control levels after 12 hours and slightly increases after 24 hours.
PTM: Contains three disulfide bonds 24-38; 27-45; 39-46 and Lysine amide at position 50."	"Gram-positive bacterium: Micrococcus luteus;##Gram-negative bacterium: Escherichia coli.##Fungi: Neurospora crassa, Fusarium oxysporum, Saccharomyces cerevisiae TGY."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	11028917##9353298##10561573	Cell Mol Life Sci. 2000 Aug;57(8-9):1260-1271.##J Biol Chem. 1997 Nov 7;272(45):28398-28406.##Eur J Biochem. 1999 Dec;266(2):335-346.	"Destoumieux D, Munoz M, Bulet P, Bach¨¨re E.##Destoumieux D, Bulet P, Loew D, Van Dorsselaer A, Rodriguez J, Bach¨¨re E.##Destoumieux D, Bulet P, Strub JM, Van Dorsselaer A, Bach¨¨re E."	"Penaeidins, a family of antimicrobial peptides from penaeid shrimp (Crustacea, Decapoda).##Penaeidins, a new family of antimicrobial peptides isolated from the shrimp Penaeus vannamei (Decapoda).##Recombinant expression and range of activity of penaeidins, antimicrobial peptides from penaeid shrimp."
DRAMP02572	YRGGYTGPIPRPPPIGRPPLRPVCNACYRLSVSDARNCCIKFGSCCHLVK	50	"Penaeidin-2b (Pen-2b; shrimps, Arthropods, animals)"	Q963C4	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains three disulfide bonds 24-38; 27-45; 39-46 and lysine amide at K50."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02575	QVYKGGYTRPVPRPPPFVRPLPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYS	62	"Penaeidin-3b (Pen-3b; shrimps, Arthropods, animals)"	P81059	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Tissue specificity: Higher expression in hemocytes and to a lesser extent in heart, testis, gills, intestine, lymphonoid organ and hepatopancreas. Traces in eyes and subcuticular epithelium. Not present in the brain.
Developmental stage: Expression decreases 3 hours after microbial challenge to return to control levels after 12 hours and slightly increases after 24 hours.
PTM: Contains three disulfide bonds 32-47; 36-54; 48-55, Pyrrolidone carboxylic acid and Lysine amide at position 1 and 62 respectively."	"Gram-positive bacterium: Micrococcus luteus;##Gram-negative bacterium: Escherichia coli.##Fungi: Neurospora crassa, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	11028917##10639333	Cell Mol Life Sci. 2000 Aug;57(8-9):1260-1271.##J Cell Sci. 2000 Feb;113 (Pt 3):461-469.	"Destoumieux D, Munoz M, Bulet P, Bach¨¨re E.##Destoumieux D, Mu?oz M, Cosseau C, Rodriguez J, Bulet P, Comps M, Bach¨¨re E."	"Penaeidins, a family of antimicrobial peptides from penaeid shrimp (Crustacea, Decapoda).##Penaeidins, antimicrobial peptides with chitin-binding activity, are produced and stored in shrimp granulocytes and released after microbial challenge."
DRAMP02576	QVYKGGYTRPIPRPPFVRPVPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYS	61	"Penaeidin-3c (Pen-3c; shrimps, Arthropods, animals)"	P81060	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Tissue specificity: Higher expression in hemocytes and to a lesser extent in heart, testis, gills, intestine, lymphonoid organ and hepatopancreas. Traces in eyes and subcuticular epithelium. Not present in the brain.
Developmental stage: Expression decreases 3 hours after microbial challenge to return to control levels after 12 hours and slightly increases after 24 hours.
PTM: Contains three disulfide bonds 31-46; 35-53; 47-54, Pyrrolidone carboxylic acid and Lysine amide at position 1 and 62 respectively."	"Gram-positive bacterium: Micrococcus luteus;##Gram-negative bacterium: Escherichia coli.##Fungi: Neurospora crassa, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	11028917##10639333	Cell Mol Life Sci. 2000 Aug;57(8-9):1260-1271.##J Cell Sci. 2000 Feb;113 (Pt 3):461-469.	"Destoumieux D, Munoz M, Bulet P, Bach¨¨re E.##Destoumieux D, Mu?oz M, Cosseau C, Rodriguez J, Bulet P, Comps M, Bach¨¨re E."	"Penaeidins, a family of antimicrobial peptides from penaeid shrimp (Crustacea, Decapoda).##Penaeidins, antimicrobial peptides with chitin-binding activity, are produced and stored in shrimp granulocytes and released after microbial challenge."
DRAMP02577	QVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPISCRGISFSQARSCCSRLGRCCHVGKGYS	62	"Penaeidin-3d (Pen-3d; shrimps, Arthropods, animals)"	Q963D0	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains three disulfide bonds 32-47; 36-54; 48-55, Pyrrolidone carboxylic acid and Serine amide at position 1 and 62 respectively."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02580	QVYKGGYTRPIPRPPPFVRPLPGGPISPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYS	62	"Penaeidin-3g (Pen-3g; shrimps, Arthropods, animals)"	Q963C7	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains three disulfide bonds 32-47; 36-54; 48-55, Pyrrolidone carboxylic acid and Serine amide at position 1 and 62 respectively."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02581	QVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPISCRGISFSQARSYCSRLGRCCHVGKGYS	62	"Penaeidin-3h (Pen-3h; shrimps, Arthropods, animals)"	Q963C6	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains two disulfide bonds 36-54; 48-55, Pyrrolidone carboxylic acid and Serine amide at position 1 and 62 respectively."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02582	QVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGRPVSCRGISFSQARSCCSRLGRCCHVGKGYS	62	"Penaeidin-3i (Pen-3i; shrimps, Arthropods, animals)"	Q963C5	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains two disulfide bonds 36-54; 48-55, Pyrrolidone carboxylic acid and Serine amide at position 1 and 62 respectively."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02583	QVYKGGYTRPVPRPPFVRPLPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYS	61	"Penaeidin-3j (Pen-3j; shrimps, Arthropods, animals)"	Q963D9	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains three disulfide bonds 31-46; 35-53; 47-54, Pyrrolidone carboxylic acid and Serine amide at position 1 and 61 respectively."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02585	YSSGYTRPLPKPSRPIFIRPIGCDVCYGIPSSTARLCCFRYGDCCHR	47	"Penaeidin-4c (Pen-4c; shrimps, Arthropods, animals)"	Q963C3	Belongs to the penaeidin family	Not found	Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity (By similarity).
PTM: Contains three disulfide bonds 23-37; 26-44; 38-45 and C-terminal amidation."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445.	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02587	QGYKGPYTRPILRPYVRPVVSYNACTLSCRGITTTQARSCCTRLGRCCHVAKGYS	55	"Penaeidin-3k (Pen-3k; shrimps, Arthropods, animals)"	Q962B2	Belongs to the penaeidin family	Not found	Litopenaeus setiferus (Atlantic white shrimp) (Penaeus setiferus)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains three disulfide bonds 25-40; 29-47; 41-48, Pyrrolidone carboxylic acid and Serine amide at position 1 and 55 respectively."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02588	QGYKGPYTRPILRPYVRPVVSYNVCTLSCRGITTTQARSCCTRLGRCCHVAKGYS	55	"Penaeidin-3l (Pen-3l; shrimps, Arthropods, animals)"	Q962A8	Belongs to the penaeidin family	Not found	Litopenaeus setiferus (Atlantic white shrimp) (Penaeus setiferus)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains three disulfide bonds 25-40; 29-47; 41-48, Pyrrolidone carboxylic acid and Serine amide at position 1 and 55 respectively."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02589	QGCKGPYTRPILRPYVRPVVSYNACTLSCRGITTTQARSCCTRLGRCCHVAKGYS	55	"Penaeidin-3m (Pen-3m; shrimps, Arthropods, animals)"	Q962B1	Belongs to the penaeidin family	Not found	Litopenaeus setiferus (Atlantic white shrimp) (Penaeus setiferus)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains three disulfide bonds 25-40; 29-47; 41-48, Pyrrolidone carboxylic acid and Serine amide at position 1 and 55 respectively."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02590	QGYKGPYTRPILRPYVRPVVSYNACTLSCRGITTTQARSCSTRLGRCCHVAKGYS	55	"Penaeidin-3n (Pen-3n; shrimps, Arthropods, animals)"	Q962B0	Belongs to the penaeidin family	Not found	Litopenaeus setiferus (Atlantic white shrimp) (Penaeus setiferus)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Posesses antibacterial and antifungal activity. Presents chitin-binding activity (By similarity).
Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
PTM: Contains two disulfide bonds 25-40; 29-47, Pyrrolidone carboxylic acid and Serine amide at position 1 and 55 respectively."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12242595	Immunogenetics. 2002 Sep;54(6):442-445. 	"Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS."	Diversity of the penaeidin antimicrobial peptides in two shrimp species.
DRAMP02597	VFQFLGKIIHHVGNFVHGFSHVF	23	"Clavanin-A (His-rich; chordates, animals)"	"P80710, O18490"	Not found	Not found	Styela clava (Sea squirt)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Alpha helix	Not found	None	Function: Has antimicrobial activity.	Gram-negative bacterium: Escherichia coli;##yeast Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9001389##9237689	FEBS Lett. 1997 Jun 30;410(2-3):490-492.##FEBS Lett. 1997 Jan 3;400(2):158-162.	"Lee IH, Zhao C, Cho Y, Harwig SSL, Cooper EL, Lehrer RI.##Zhao C, Lian H, Lee I.H, Lehrer R.I."	"Clavanins, alpha-helical antimicrobial peptides from tunicate hemocytes.##cDNA cloning of Clavanins: antimicrobial peptides of tunicate hemocytes."
DRAMP02598	VFQFLGRIIHHVGNFVHGFSHVF	23	"Clavanin-B (His-rich; chordates, animals)"	P80711	Not found	Not found	Styela clava (Sea squirt)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: Has antimicrobial activity.
PTM: C-terminal amidation."	"Escherichia coli, L. monocytes, Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9001389	 FEBS Lett. 1997 Jan 3;400(2):158-162.	"Lee IH, Zhao C, Cho Y, Harwig SS, Cooper EL, Lehrer RI."	"Clavanins, alpha-helical antimicrobial peptides from tunicate hemocytes."
DRAMP02599	VFHLLGKIIHHVGNFVYGFSHVF	23	"Clavanin-C (His-rich; chordates, animals)"	"O18493, P80712"	Not found	Not found	Styela clava (Sea squirt)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Has antimicrobial activity.
Tissue specificity: Hemocytes and pharyngeal tissues."	Gram-negative bacterium: Escherichia coli;##yeast Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9001389##9237689	FEBS Lett. 1997 Jun 30;410(2-3):490-492.##FEBS Lett. 1997 Jan 3;400(2):158-162.	"Lee IH, Zhao C, Cho Y, Harwig SSL, Cooper EL, Lehrer RI.##Zhao C, Lian H, Lee I.H, Lehrer R.I."	"Clavanins, alpha-helical antimicrobial peptides from tunicate hemocytes.##cDNA cloning of Clavanins: antimicrobial peptides of tunicate hemocytes."
DRAMP02600	AFKLLGRIIHHVGNFVYGFSHVF	23	"Clavanin-D (His-rich; chordates, animals)"	"P80713, O18491"	Not found	Not found	Styela clava (Sea squirt)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: Has antimicrobial activity.
Tissue specificity: Hemocytes and pharyngeal tissues."	Gram-negative bacterium: Escherichia coli;##yeast Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9237689##9001389	FEBS Lett. 1997 Jun 30;410(2-3):490-492.##FEBS Lett. 1997 Jan 3;400(2):158-162.	"Zhao C, Liaw L, Lee IH, Lehrer RI.##Lee IH, Zhao C, Cho Y, Harwig SS, Cooper EL, Lehrer RI."	"cDNA cloning of Clavanins: antimicrobial peptides of tunicate hemocytes.##Clavanins, alpha-helical antimicrobial peptides from tunicate hemocytes."
DRAMP02601	LFKLLGKIIHHVGNFVHGFSHVF	23	"Clavanin E (His-rich; chordates, animals)"	O18492	Not found	Not found	Styela clava (Sea squirt)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Has antimicrobial activity.	Gram-negative bacterium: Escherichia coli;##yeast Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9237689	FEBS Lett. 1997 Jun 30;410(2-3):490-492. 	"Zhao C, Liaw L, Lee IH, Lehrer RI."	cDNA cloning of Clavanins: antimicrobial peptides of tunicate hemocytes. 
DRAMP02613	DSHEERRQGRHGHHEYGRKFHEKHHSHRGY	30	"Mfa-hst 5 (M.fascicularis histatin 5; primates, mammals, animals)"	No entry found	Not found	Not found	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	"Antimicrobial, Antifungal"	Not found	Alpha helix (CD)	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20423320	Protein Pept Lett. 2010 Jul;17(7):909-918.	"Padovan L, Segat L, Pontillo A, Antcheva N, Tossi A, Crovella S."	Histatins In Non-Human Primates: Gene Variations and Functional Effects.
DRAMP02623	DSHEERHHGRHGHHKYGRKFHEKHHSHRGYRSNYLYDN	38	"Macaque histatin (His-rich; M-Histatin 1; primates, mammals, animals)"	P34084	Belongs to the histatin family	HTN1	Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2229609	J Dent Res. 1990 Nov;69(11):1717-1723.	"Xu T, Telser E, Troxler RF, Oppenheim FG."	"Primary structure and anticandidal activity of the major histatin from parotid secretion of the subhuman primate, Macaca fascicularis."
DRAMP18249	DWTFANWSCLVCDDCSVNLTV	21	Bac-GM100  (Bacteriocin)	No entry found	Belongs to the class IId bacteriocin	Not found	Brevibacillus brevis strain GM100	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	Not found	None	The 21 N-terminal residues of Bac-GM100 displayed 65% homology with thurincin H from Bacillus thuringiensis. Bac-GM100 was extremely heat-stable and was stable within a pH range of 3-10. It proved sensitive to various proteases.	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23291759	Biosci Biotechnol Biochem. 2013;77(1):151-60.	"Ghadbane M, Harzallah D, Laribi AI, Jaouadi B, Belhadj H."	Purification and biochemical characterization of a highly thermostable bacteriocin isolated from Brevibacillus brevis strain GM100.
DRAMP02639	RCICVLGIC	9	"Demidefensin-3 (primates, mammals, animals)"	Q9GLR2	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus macaque)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	"Function: Has antimicrobial activities against bacteria and fungi (By similarity).
Subunit structure: Forms a cyclic homodimer; disulfide-linked (By similarity).
PTM: This is a cyclic peptide (By similarity).
Caution: The mature 9-residue peptide is expected to be found in 18-residue cyclopeptides produced by combinatorial peptide splicing either with itself or with other demidefensins. However among cyclopeptides screened for antimicrobial activity, no peptides that would have been produced from this sequence were detected."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11527997	J Leukoc Biol. 2001 Sep;70(3):461-464.	"Leonova L, Kokryakov VN, Aleshina G, Hong T, Nguyen T, Zhao C, Waring AJ, Lehrer RI."	Circular minidefensins and posttranslational generation of molecular diversity.
DRAMP02640	RCLCRRGVC	9	"Rhesus theta defensin-1/2 subunit B (RTD-1b; primates, mammals, animals)"	P82271	Belongs to the alpha-defensin family (Theta subfamily)	RTD1B	Macaca mulatta (Rhesus macaque)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	PTM: contains one disulfide bond 4-9.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10521339##1152799##11675394	Science. 1999 Oct 15;286(5439):498-502.##J Leukoc Biol. 2001 Sep;70(3):461-464.##J Biol Chem. 2002 Feb 1;277(5):3079-3084.	"Tang YQ, Yuan J, Osapay G, Osapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME.##Leonova L, Kokryakov VN, Aleshina G, Hong T, Nguyen T, Zhao C, Waring AJ, Lehrer RI.##Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME."	"A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins.##Circular minidefensins and posttranslational generation of molecular diversity.##Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides."
DRAMP02641	RCICTRGFC	9	"Rhesus theta defensin-1/3 subunit A (RTD-1a; primates, mammals, animals)"	"P82270, Q9TU01"	Belongs to the alpha-defensin family (Theta subfamily)	RTD1A	Macaca mulatta (Rhesus macaque)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	PTM: contains one disulfide bond 4-9.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10521339##1152799##11675394	Science. 1999 Oct 15;286(5439):498-502.##J Leukoc Biol. 2001 Sep;70(3):461-464.##J Biol Chem. 2002 Feb 1;277(5):3079-3084.	"Tang YQ, Yuan J, Osapay G, Osapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME.##Leonova L, Kokryakov VN, Aleshina G, Hong T, Nguyen T, Zhao C, Waring AJ, Lehrer RI.##Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME."	"A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins.##Circular minidefensins and posttranslational generation of molecular diversity.##Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides."
DRAMP02642	GFCRCLCRRGVCRCICTR	18	"Rhesus theta-defensin 1 (RTD-1; primates, mammals, animals)"	"P82271, P82270, Q9TU01"	Belongs to the alpha-defensin family (Theta subfamily)	Not found	Macaca mulatta (Rhesus macaque)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral"	Protein level	Beta strand (4 strands; 10 residues)	Not found	1HVZ resolved by NMR.	"Function: RTD-1 and RTD-2 have similar antimicrobial activities against the Gram-positive bacteria S. aureus 502A and L. monocytogenes, the Gram-negative bacterium S. typhimurium, and the fungi C. albicans 16820 and C. neoformans 271A. RTD-2 is 2-3-fold less active than RTD-1 against E. coli ML35.
Subunit structure: RTD-1 is a cyclic heterodimer composed of subunits A and B; disulfide-linked.
Tissue specificity: RTD-1 is expressed in bone marrow. Detected in promyelocytes, myelocytes and mature neutrophils and monocytes.
Developmental stage: RTD-1 expression begins early during granulocyte myelopoiesis.
PTM: Forms a cyclic peptide with 1 subunit B (RTD-2) or with 1 subunit A (RTD-1). An additional intersubunit disulfide bond is formed.
Miscellaneous: RTD-1 is 10-fold more present in cells than RTD-2."	"Gram-positive bacteria: Staphylococcus aureus 502a and Listeria monocytogenes;##Gram-negative bacteria: Salmonella typhimurium, Escherichia coli ML35.##Fungi: Candida albicans 16820, Cryptococcus neoformans 271A (the activity of RTD-2 against Escherichia coli ML35 was 2-3-fold less than those of RTD-1 and RTD-3)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bonds between Cys3 and Cys16,Cys5 and Cys14,Cys7 and Cys12."	L	No cytotoxicity information found	Not found	10521339##1152799##11675394	Science. 1999 Oct 15;286(5439):498-502.##J Leukoc Biol. 2001 Sep;70(3):461-464.##J Biol Chem. 2002 Feb 1;277(5):3079-3084.	"Tang YQ, Yuan J, Osapay G, Osapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME.##Leonova L, Kokryakov VN, Aleshina G, Hong T, Nguyen T, Zhao C, Waring AJ, Lehrer RI.##Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME."	"A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins.##Circular minidefensins and posttranslational generation of molecular diversity.##Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides."
DRAMP02643	RCLCRRGVCRCLCRRGVC	18	"Rhesus theta-defensin 2 (RTD-2; primates, mammals, animals)"	P82271	Belongs to the alpha-defensin family (Theta subfamily)	Not found	Macaca mulatta (Rhesus macaque)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	None	"Function: RTD-1 and RTD-2 have similar antimicrobial activities against the Gram-positive bacteria S. aureus 502A and L. monocytogenes, the Gram-negative bacterium S. typhimurium, and the fungi C. albicans 16820 and C. neoformans 271A. RTD-2 is 2-3-fold less active than RTD-1 against E. coli ML35.
Subunit structure: RTD-2 is a cyclic homodimer composed of two subunits B; disulfide-linked.
PTM: Forms a cyclic peptide with 1 subunit B (RTD-2) or with 1 subunit A (RTD-1). An additional intersubunit disulfide bond is formed.
Miscellaneous: RTD-1 is 10-fold more present in cells than RTD-2."	"Gram-positive bacteria: Staphylococcus aureus 502a, Listeria monocytogenes; ##Gram-negative bacteria: Salmonella typhimurium, Escherichia coli ML35.##Fungi: Candida albicans 16820, Cryptococcus neoformans 271A (the activity of RTD-2 against Escherichia coli ML35 was 2-3-fold less than those of RTD-1 and RTD-3)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10521339##1152799##11675394	Science. 1999 Oct 15;286(5439):498-502.##J Leukoc Biol. 2001 Sep;70(3):461-464.##J Biol Chem. 2002 Feb 1;277(5):3079-3084.	"Tang YQ, Yuan J, Osapay G, Osapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME.##Leonova L, Kokryakov VN, Aleshina G, Hong T, Nguyen T, Zhao C, Waring AJ, Lehrer RI.##Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME."	"A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins.##Circular minidefensins and posttranslational generation of molecular diversity.##Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides."
DRAMP02645	GICRCICTRGFCRCICVL	18	"Rhesus theta-defensin 4 (RTD-4; primates, mammals, animals)"	No entry found	Belongs to the alpha-defensin family (Theta subfamily)	Not found	Macaca mulatta (Rhesus macaque)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Function: RTD-1 and RTD-5 are 3-fold more active than RTD-4.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21084627	J Leukoc Biol. 2011 Feb;89(2):283-290.	"Tongaonkar P, Tran P, Roberts K, Schaal J, Osapay G, Tran D, Ouellette AJ, Selsted ME."	"Rhesus macaque {theta}-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities."
DRAMP02646	GICRCLCRRGVCRCICVL	18	"Rhesus theta-defensin 5 (RTD-5; primates, mammals, animals)"	No entry found	Belongs to the alpha-defensin family (Theta subfamily)	Not found	Macaca mulatta (Rhesus macaque)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Function: RTD-1 and RTD-5 are 3-fold more active than RTD-4. RTD-6 has not be collected due to the lack of activity.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21084627	J Leukoc Biol. 2011 Feb;89(2):283-290.	"Tongaonkar P, Tran P, Roberts K, Schaal J, Osapay G, Tran D, Ouellette AJ, Selsted ME."	"Rhesus macaque {theta}-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities."
DRAMP02653	ACYCRIPACLAGERRYGTCFYLGRVWAFCC	30	"Neutrophil defensin 1 (RMAD-1; primates, mammals, animals)"	P60030	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus macaque) 	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	None	Function: Has antibacterial and antifungal activiy. 	Gram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacterium: Escherichia coli.##Fungi: Cryptococcus neoformans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10531277	Infect Immun. 1999 Nov;67(11):6139-6144.	"Tang YQ, Yuan J, Miller CJ, Selsted ME."	"Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes."
DRAMP02654	ACYCRIPACLAGERRYGTCFYMGRVWAFCC	30	"Neutrophil defensin 2 (RMAD-2; primates, mammals, animals)"	P82317	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus macaque) 	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	None	Function: Has antibacterial and antifungal activiy. 	Gram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacterium: Escherichia coli.##Fungi: Cryptococcus neoformans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10531277	Infect Immun. 1999 Nov;67(11):6139-6144.	"Tang YQ, Yuan J, Miller CJ, Selsted ME."	"Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes."
DRAMP02659	ACYCRIPACLAGERRYGTCFYRRRVWAFCC	30	"Neutrophil defensin 3 (RMAD-3; primates, mammals, animals)"	"P60031, P82318"	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus monkey)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	None	"Function: Has bacteriostatic and antifungal activity.
PTM: Contains three disulfide bonds: 2-30; 4-19; 9-29."	Gram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacteria: Escherichia coli.##Fungi: Cryptococcus neoformans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10531277	Infect Immun. 1999 Nov;67(11):6139-6144.	"Tang YQ, Yuan J, Miller CJ, Selsted ME."	"Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes."
DRAMP02660	RRTCRCRFGRCFRRESYSGSCNINGRIFSLCCR	33	"Neutrophil defensin 4 (RMAD-4; primates, mammals, animals)"	P82319	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus monkey)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	None	"Function: Defensins 4 has bacteriostatic and antifungal activity.
PTM: Contains three disulfide bonds 4-32; 6-21; 11-31."	Gram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacteria: Escherichia coli.##Fungi: Cryptococcus neoformans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10531277	Infect Immun. 1999 Nov;67(11):6139-6144.	"Tang YQ, Yuan J, Miller CJ, Selsted ME."	"Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes."
DRAMP02661	RTCRCRFGRCFRRESYSGSCNINGRIFSLCCR	32	"Neutrophil defensin 5 (RMAD-5; primates, mammals, animals)"	P82319	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus monkey)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	None	"Function: Defensins 5 has bacteriostatic and antifungal activity.
PTM: Contains three disulfide bonds 3-31; 5-20; 10-30."	Gram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacteria: Escherichia coli.##Fungi: Cryptococcus neoformans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10531277	Infect Immun. 1999 Nov;67(11):6139-6144.	"Tang YQ, Yuan J, Miller CJ, Selsted ME."	"Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes."
DRAMP02662	RRTCRCRFGRCFRRESYSGSCNINGRISSLCCR	33	"Neutrophil defensin 6 (RMAD-6; primates, mammals, animals)"	P82320	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus monkey)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	None	"Function: Defensins 6 has bacteriostatic and antifungal activity.
PTM: Contains three disulfide bonds 65-93; 67-82; 72-92."	Gram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacteria: Escherichia coli.##Fungi: Cryptococcus neoformans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10531277	Infect Immun. 1999 Nov;67(11):6139-6144.	"Tang YQ, Yuan J, Miller CJ, Selsted ME."	"Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes."
DRAMP02663	RTCRCRFGRCFRRESYSGSCNINGRISSLCCR	32	"Neutrophil defensin 7 (RMAD-7; primates, mammals, animals)"	P82320	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus monkey)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge 	Not found	None	"Function: Defensins 7 has bacteriostatic and antifungal activity.
PTM: Contains three disulfide bonds 65-93; 67-82; 72-93."	Gram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacteria: Escherichia coli.##Fungi: Cryptococcus neoformans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10531277	Infect Immun. 1999 Nov;67(11):6139-6144.	"Tang YQ, Yuan J, Miller CJ, Selsted ME."	"Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes."
DRAMP02664	ACYCRIPACLAGERRYGTCFYLRRVWAFCC	30	"Neutrophil defensin 8 (RMAD-8; primates, mammals, animals)"	"P60032, P82318"	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus monkey)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Bridge	Not found	None	"Function: Probable antibiotic and antifungal activity.
PTM: Contains three disulfide bonds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10531277	Infect Immun. 1999 Nov;67(11):6139-6144.	"Tang YQ, Yuan J, Miller CJ, Selsted ME."	"Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes."
DRAMP02669	ACYCRIPACLAGERRYGTCIYQGRLWAFCC	30	"Neutrophil defensin 1 (Defensin, alpha 1; primates, mammals, animals)"	Q5G863	Belongs to the alpha-defensin family	DEFA1	Pan troglodytes (chimpanzee)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Homology	Bridge	Not found	None	MOA: Defensins are thought to kill microbes by permeabilizing their plasma membrane.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15494476	Physiol Genomics. 2004 Dec 15;20(1):1-11. Epub 2004 Oct 19.	"Patil A, Hughes AL, Zhang G."	Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.
DRAMP02670	VCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRVD	34	"Neutrophil defensin 4 (Defensin, alpha 4; primates, mammals, animals)"	Q5G862	Belongs to the alpha-defensin family	DEFA4	Pan troglodytes (chimpanzee)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Bridge	Not found	None	"Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Inhibits corticotropin (ACTH)-stimulated corticosterone production."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15494476	Physiol Genomics. 2004 Dec 15;20(1):1-11. 	"Patil A, Hughes AL, Zhang G."	Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.
DRAMP02698	RRTCHCRSRCLRRESNSGSCNINGRIFSLCCR	32	"Rhesus macaque oral alpha-defensins (ROADs; primates, mammals, animals)"	B5AKV3	Belongs to the alpha-defensin family	Not found	Macaca mulatta (Rhesus monkey)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Beta strand (3 strands; 19 residues)	NMR spectroscopy shows that Synthetic ROAD-1 adopts the canonical disulfide pairing and alpha-defensin fold.	2K1I resolved by NMR.	"Function: ROAD-1 is active against Staphylococcus aureus, Escherichia coli, and Candida albicans in a concentration-dependent manner. The antimicrobial mechanism of defensins has been correlated with their ability to disrupt and permeabilize the cell envelope, activities that depend on the surface features of the folded peptide.
PTM: Contains three disulfide bonds."	Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacterium: Escherichia coli.##Fungi: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bonds between Cys4 and Cys31; Cys6 and Cys20; Cys10 and Cys30.	L	No cytotoxicity information found	Not found	18930922	J Biol Chem. 2008 Dec 19;283(51):35869-35877.	"Vasudevan S, Yuan J, Osapay G, Tran P, Tai K, Liang W, Kumar V, Selsted ME, Cocco MJ."	"Synthesis, structure, and activities of an oral mucosal alpha-defensin from rhesus macaque."
DRAMP18242	EKYTEVPEYV	10	Fengycin B2 (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus thuringiensis 	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	K2 is Orn. The C-terminal V forms an ester bond with the side chain of Y3.	None	Fuction: Active against fungi C. Albicans and A.niger. 	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	24312083##22847390 	Front Microbiol. 2013 Nov 21;4:332.##J Am Soc Mass Spectrom. 2012 Oct;23(10):1716-28. Epub 2012 Jul 31. 	"Roy A, Mahata D, Paul D, Korpole S, Franco OL, Mandal SM.##Pathak KV, Keharia H, Gupta K, Thakur SS, Balaram P."	"Purification, biochemical characterization and self-assembled structure of a fengycin-like antifungal peptide from Bacillus thuringiensis strain SM1.##Lipopeptides from the banyan endophyte, Bacillus subtilis K1: mass spectrometric characterization of a library of fengycins."
DRAMP18240	EKYTEIPEYV	10	Fengycin C(Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis K1	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	K2 is Orn.	None	Comment: No comments found on DRAMP database	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22847390	J Am Soc Mass Spectrom. 2012 Oct;23(10):1716-28. Epub 2012 Jul 31.	"Pathak KV, Keharia H, Gupta K, Thakur SS, Balaram P."	"Lipopeptides from the banyan endophyte, Bacillus subtilis K1: mass spectrometric characterization of a library of fengycins."
DRAMP18239	EKYTEAPEYV	10	Fengycin A2(Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis K1	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	K2 is Orn. The C-terminal V forms an ester bond with the side chain of Y3.	None	Comment: No comments found on DRAMP database	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22847390	J Am Soc Mass Spectrom. 2012 Oct;23(10):1716-28. Epub 2012 Jul 31.	"Pathak KV, Keharia H, Gupta K, Thakur SS, Balaram P."	"Lipopeptides from the banyan endophyte, Bacillus subtilis K1: mass spectrometric characterization of a library of fengycins."
DRAMP18238	EKYTEVPEYI	10	Fengycin B(Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis K1	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	K2 is Orn. The structure consists of a cyclic peptide lactone formed between the phenolic -OH of Tyr3 and the C-terminal -COOH of an amino acid at position 10. The N-terminus of the decapeptide segment is acylated with a beta-hydroxy fatty acid (beta-OH FA).	None	Comment: No comments found on DRAMP database	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22847390	J Am Soc Mass Spectrom. 2012 Oct;23(10):1716-28. Epub 2012 Jul 31.	"Pathak KV, Keharia H, Gupta K, Thakur SS, Balaram P."	"Lipopeptides from the banyan endophyte, Bacillus subtilis K1: mass spectrometric characterization of a library of fengycins."
DRAMP18237	EKYTEAPEYI	10	Fengycin A(Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis K1	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	K2 is Orn. The structure consists of a cyclic peptide lactone formed between the phenolic -OH of Tyr3 and the C-terminal -COOH of an amino acid at position 10. The N-terminus of the decapeptide segment is acylated with a beta-hydroxy fatty acid (beta-OH FA).	None	Comment: No comments found on DRAMP database	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22847390	J Am Soc Mass Spectrom. 2012 Oct;23(10):1716-28. Epub 2012 Jul 31.	"Pathak KV, Keharia H, Gupta K, Thakur SS, Balaram P."	"Lipopeptides from the banyan endophyte, Bacillus subtilis K1: mass spectrometric characterization of a library of fengycins."
DRAMP02743	AVRIGPCDQVCPRIVPERHECCRAHGRSGYAYCSGGGMYCN	41	Diapause-specific peptide (Dsp)	Q8T0W8	Belongs to the diapausin family	Not found	Gastrophysa atrocyanea	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	Not found	2E2F resolved by NMR.	"Function: Has antifungal activity against Trichophyton rubrum. Blocks voltage-dependent N-type calcium channels (Cav2.2 / CACNA1B).
Tissue specificity: Highly expressed in the fat body.
Developmental stage: Produced throughout adult diapause, and to a minor extent in pupae, but not in eggs, larvae, or post-diapausing adults. Inhibition of DSP expression does not affect the onset or maintenance of diapause, indicating that the expression of DSP accompanies but does not play a direct role in the induction or maintenance of diapause."	Trichophyton rubrum.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17994764	Appl. Entomol. Zool. 1998; 33: 535-543.	Tanaka H et al. Suzuki K	"A specific peptide produced during adult diapause of the leaf beetle, Gastrophysa atrocyanea Moschulsky (Coleoptara: Chrysomelidae)"
DRAMP03743	RSVCRQIKICRRRGGCYYKCTNRPY	25	"Androctonin (Arthropods, animals)"	P56684	Not found	Not found	Androctonus australis (Sahara scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Beta strand (2 strands; 8 residues)	The structure of androctonin involves a well-defined highly twisted anti-parallel beta-sheet with strands connected by a more variable positively charged turn.	1CZ6 resolved by NMR.	"Function: Androctonin is a highly cationic antimicrobial peptide from scorpion exhibiting a broad spectrum of activities against bacteria (Gram-positive and Gram-negative) and filamentous fungi. Acts on the membrane of the bacterial cells. It destabilize a membrane by modifying its properties.
PTM: Contains two disulfide bonds 4-20; 10-16."	"[Ref.10942757] Gram-positive bacteria: Micrococcus luteus (MIC=0.6-1.5 ¦ÌM), Aerococcus viridans (MIC=0.3-0.6 ¦ÌM), Staphylococcus aureus (MIC=15-30 ¦ÌM);##Gram-negative bacteria: Escherichia coli D31 (MIC=3-6 ¦ÌM),  Escherichia coli D22 (MIC=6-15 ¦ÌM),  Escherichia coli 1106 (MIC=6-15 ¦ÌM), Salmonella typhimurium (MIC=3-6 ¦ÌM).##Fungi: Alternaria brassicola (MIC=3-6 ¦ÌM), Fusarium culmorum (MIC=3-6 ¦ÌM), Fusarium oxysporum (MIC=6-12 ¦ÌM), Neurospora crassa (MIC=6-12 ¦ÌM), Nectria haematococca (MIC=6-12 ¦ÌM), Trichoderma viridae (MIC=6-12 ¦ÌM);##Yeast: Candida albicans (MIC=1.6-3.15 ¦ÌM).##[Ref.8939880] Gram-positive bacteria: Bacillus subtilis (MIC=1.5-3.0 ¦ÌM);##Gram-negative bacteria: Escherichia coli D22 (MIC>30 ¦ÌM), Pseudomonas syringae (MIC=1.5-3.0 ¦ÌM), Pseudomonas syringae pv.syringae (MIC=15-22 ¦ÌM), Pseudomonas syringae phaseoli (MIC=1.5-3.0 ¦ÌM), Pseudomonas syringae pv.pisi (MIC=6-15 ¦ÌM), Pseudomonas syringae pv. maculicola (MIC=3-6 ¦ÌM), Phoma valerianella (MIC=15-22 ¦ÌM), Xanthomonas compestris pv.compestris (MIC=3-6 ¦ÌM), Xanthomonas vesicatoria 687.3 (MIC=1.5-3.0 ¦ÌM), Xanthomonas vesicatoria B229RI (MIC=1.5-3.0 ¦ÌM);##Fungi: Alternaria dauci (MIC=8-16 ¦ÌM), Stemphylium (MIC=4-8 ¦ÌM),  Fusarium oxysporum M. (MIC=2-4 ¦ÌM), Fusarium oxysporum L. (MIC=2-4 ¦ÌM), Botrytis cinerea (MIC=6-12 ¦ÌM), B. petunia (MIC=4-8 ¦ÌM), Verticilium toreilis (MIC=2-4 ¦ÌM), Aspergillus fumigatus (MIC=25-50 ¦ÌM)."	[Ref.8939880] It exhibits no hemolytic activity on porcine or bovine erythrocytes at a concentration of up to 150 ¦ÌM.	Cyclic	Free	Free	"Disulfide bond between Cys4 and Cys20,Cys10 and Cys16."	L	No cytotoxicity information found	Cell membrane	8939880##10563585##10942757	J Biol Chem. 1996 Nov 22;271(47):29537-29544.##J Biomol Struct Dyn. 1999 Oct;17(2):367-380.##J Biol Chem. 2000 Oct 27;275(43):33464-70.	"Ehret-Sabatier L, Loew D, Goyffon M, Fehlbaum P, Hoffmann JA, van Dorsselaer A, Bulet P.##Mandard N, Sy D, Maufrais C, Bonmatin JM, Bulet P, Hetru C, Vovelle F.##Silva PI Jr, Daffre S, Bulet P."	"Characterization of novel cysteine-rich antimicrobial peptides from scorpion blood.##Androctonin, a novel antimicrobial peptide from scorpion Androctonus australis: solution structure and molecular dynamics simulations in the presence of a lipid monolayer.##Isolation and characterization of gomesin, an 18-residue cysteine-rich defense peptide from the spider Acanthoscurria gomesiana hemocytes with sequence similarities to horseshoe crab antimicrobial peptides of the tachyplesin family."
DRAMP02753	GWKDWAKKAGGWLKKKGPGMAKAALKAAMQ	30	"Ponericin G1 (ants, insects, animals)"	P82414	Not found	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	MOA: The comparison of ponericins with those well-studied peptides suggests that ponericins may adopt an amphipathic alpha-helical structure on cell membranes.	"B. cereus CIP 6624a, Bacillus megaterium ATCC 9885b, B.stearothermophilus CIP 675, B.stearothermophilus CIP 675, Bacillus subtilis ATCC 6623, Enterococcus faecalis CIP 636, Lactococcus lactis ssp. cremoris I116, Streptococcus pyogenes CIP 561, S. sanguinis CIP 55128, Listeria ivanovii LMA 94d, Listeria monocytogenes ATCC 15313, Micrococcus luteus CIP 5345, Staphylococcus aureus CIP 677, Staphylococcus aureus LMA, S. epidermidis CIP 53134, Escherichia coli, Enterobacter cloacae CIP 6085, Klebsiella pneumoniae CIP 8291, Proteus mirabilis LMA TP, Salmonella enterica CIP 813, Serratia marcescens LMA TP, Alcaligenes faecalis CIP 6723, Pseudomonas aeruginosa CIP A22, Proteus mirabilis LMA TP, Flavobacterium meningosepticum CIP 6057, Pseudomonas aeruginosa CIP A22, Yersinia entericolitica CIP 6529, P. putida LMA, Saccharomyces cerevisiae LMA 720"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chafotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02754	GWKDWLKKGKEWLKAKGPGIVKAALQAATQ	30	"Ponericin G2 (ants, insects, animals)"	P82415	Not found	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	MOA: The comparison of ponericins with those well-studied peptides suggests that ponericins may adopt an amphipathic alpha-helical structure on cell membranes.	Saccharomyces cerevisae	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chafotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02755	GWKDWLNKGKEWLKKKGPGIMKAALKAATQ	30	"Ponericin G3 (ants, insects, animals)"	P82416	Not found	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Not found	Not found	None	MOA: The comparison of ponericins with those well-studied peptides suggests that ponericins may adopt an amphipathic alpha-helical structure on cell membranes.	"Gram-positive bacteria: Bacillus cereus CIP 6624a, B. megaterium ATCC 9885b, B. stearothermophilus CIP 675, B. stearothermophilus CIP 675, B. subtilis ATCC 6623, Enterococcus faecalis CIP 636, Lactococcus lactis ssp. cremoris I116, Streptococcus pyogenes CIP 561, S. sanguinis CIP 55128, Listeria ivanovii LMA 94d, Listeria monocytogenes ATCC 15313, Micrococcus luteus CIP 5345, Staphylococcus aureus CIP 677, Staphylococcus aureus LMA, S. epidermidis CIP 53134;##Gram-negative bacteria: Escherichia coli, Enterobacter cloacae CIP 6085, Klebsiella pneumoniae CIP 8291, Proteus mirabilis LMA TP, Salmonella enterica CIP 813, Serratia marcescens LMA TP, Alcaligenes faecalis CIP 6723, Pseudomonas aeruginosa CIP A22, Proteus mirabilis LMA TP, Flavobacterium meningosepticum CIP 6057, Pseudomonas aeruginosa CIP A22, Yersinia entericolitica CIP 6529, P. putida LMA, Saccharomyces cerevisiae LMA 720."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chafotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02756	DFKDWMKTAGEWLKKKGPGILKAAMAAAT	29	"Ponericin G4 (ants, insects, animals)"	P82417	Not found	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Not found	Not found	None	MOA: The comparison of ponericins with those well-studied peptides suggests that ponericins may adopt an amphipathic alpha-helical structure on cell membranes.	"Gram-positive bacteria: B. cereus CIP 6624a, Bacillus megaterium ATCC 9885b, B.stearothermophilus CIP 675, B.stearothermophilus CIP 675, Bacillus subtilis ATCC 6623, Lactococcus lactis ssp. cremoris I116, Streptococcus pyogenes CIP 561, S. sanguinis CIP 55128, Micrococcus luteus CIP 5345;##Gram-negative bacteria: Klebsiella pneumoniae CIP 8291, Pseudomonas aeruginosa CIP A22, Saccharomyces cerevisae."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chafotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02758	GLVDVLGKVGGLIKKLLP	18	"Ponericin G6 (ants, insects, animals)"	P82419	Not found	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Not found	Not found	None	"Function: Has activity against Gram-positive bacteria and S. cerevisiae. Has non-hemolytic activity.
Tissue specificity: Expressed by the venom gland."	"[Ref.11279030]Gram-positive bacteria: Bacillus cereus CIP 6624a, B. megaterium ATCC 9885b, B. stearothermophilus CIP 675, B. stearothermophilus CIP 675, B. subtilis ATCC 6623, Lactococcus lactis ssp. cremoris I116, Streptococcus pyogenes CIP 561, S. sanguinis CIP 55128, Listeria monocytogenes ATCC 15313, Micrococcus luteus CIP 5345, Staphylococcus aureus CIP 677, S. epidermidis CIP 53134;##Gram-negative bacteria: Klebsiella pneumoniae CIP 8291, Pseudomonas aeruginosa CIP A22, Saccharomyces cerevisiae LMA 720."	[Ref.11279030]Non-hemolytic activity against horse and sheep erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chafotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02759	GLVDVLGKVGGLIKKLLPG	19	"Ponericin G7 (ants, insects, animals)"	P82420	Not found	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Has activity against Gram-positive bacteria and S. cerevisiae. Tissue specificity: Expressed by the venom gland.	[Swiss_Prot Entry P82420]has activity against Gram-positive bacteria and S.cerevisiae	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chafotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02762	WLGSALKIGAKLLPSVVGLFKKKKQ	25	"Ponericin-W1 (ants, insects, animals)"	P82423	Belongs to the ponericin-W family	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Insecticidal, Antifungal"	Protein level	Not found	Not found	None	"Function: Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae. Has insecticidal and hemolytic activities. 
Tissue specificity: Expressed by the venom gland."	"[Ref.11279030]Gram-positive bacteria: Bacillus cereus CIP 6624a(Inhibition zone = 10mm), B. megaterium ATCC 9885b(Inhibition zone = 12.5mm), B. stearothermophilus CIP 675(Inhibition zone = 17mm), B. subtilis ATCC 6623(Inhibition zone = 12mm), Enterococcus faecalis CIP 636(Inhibition zone = 6mm), Lactococcus lactis ssp. cremoris I116(Inhibition zone = 15mm), Streptococcus pyogenes CIP 561(Inhibition zone = 10mm), S. sanguinis CIP 55128(Inhibition zone = 7.5mm), Listeria ivanovii LMA 94d(Inhibition zone = 11.5mm), Listeria monocytogenes ATCC 15313(Inhibition zone = 9.5mm), Micrococcus luteus CIP 5345(Inhibition zone = 11.5mm), Staphylococcus aureus CIP 677(Inhibition zone = 10mm), Staphylococcus aureus LMA(Inhibition zone = 13.5mm), S. epidermidis CIP 53134(Inhibition zone = 13.5mm);##Gram-negative bacteria: Escherichia coli(Inhibition zone = 8mm), Enterobacter cloacae CIP 6085(Inhibition zone = 3mm), Klebsiella pneumoniae CIP 8291(Inhibition zone = 6.5mm), Proteus mirabilis LMA TP(no detected), Salmonella enterica CIP 813(Inhibition zone = 3mm), Serratia marcescens LMA TP(no detected), Flavobacterium meningosepticum CIP 6057(Inhibition zone = 6mm), Pseudomonas aeruginosa CIP A22(Inhibition zone = 16mm)."	[Ref.11279030]2mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 ¦Ìl of the peptide solution and placed overnight at 4¡æ to allow the diffusion of the hemolytic agent)	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chaffotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02763	WLGSALKIGAKLLPSVVGLFQKKKK	25	"Ponericin-W2 (ants, insects, animals)"	P82424	Belongs to the ponericin-W family	Not found	Pachycondyla goeldii (Ponerine ant)	"Antibacterial, Antifungal, Insecticidal, Antimicrobial"	Protein level	Not found	Not found	None	"Function: Broad spectrum of activity against both Gram-positive and Gram-negative bacteria. Has insecticidal activities. 
Tissue specificity: Expressed by the venom gland."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chaffotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02764	GIWGTLAKIGIKAVPRVISMLKKKKQ	26	"Ponericin-W3 (ants, insects, animals)"	P82425	Not found	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Insecticidal, Antifungal"	Protein level	Not found	Not found	None	"Function: Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae. Has insecticidal and hemolytic activities. 
Tissue specificity: Expressed by the venom gland."	"[Ref.11279030]Gram-positive bacteria: Bacillus cereus CIP 6624a(Inhibition zone = 10mm), B. megaterium ATCC 9885b(Inhibition zone = 13.5mm), B. stearothermophilus CIP 675(Inhibition zone = 17mm), B. subtilis ATCC 6623(Inhibition zone = 13mm), Enterococcus faecalis CIP 636(Inhibition zone = 8mm), Lactococcus lactis ssp. cremoris I116(Inhibition zone = 17.5mm), Streptococcus pyogenes CIP 561(Inhibition zone = 11.5mm), S. sanguinis CIP 55128(Inhibition zone = 10mm), Listeria ivanovii LMA 94d(Inhibition zone = 14mm), Listeria monocytogenes ATCC 15313(Inhibition zone = 11mm), Micrococcus luteus CIP 5345(Inhibition zone = 11mm), Staphylococcus aureus CIP 677(Inhibition zone = 13mm), Staphylococcus aureus LMA(Inhibition zone = 18mm), S. epidermidis CIP 53134(Inhibition zone = 15mm);##Gram-negative bacteria: Escherichia coli(Inhibition zone = 10mm), Enterobacter cloacae CIP 6085(Inhibition zone = 4mm), Klebsiella pneumoniae CIP 8291(Inhibition zone = 7.5mm), Proteus mirabilis LMA TP(no detected), Salmonella enterica CIP 813(Inhibition zone = 4mm), Serratia marcescens LMA TP(Inhibition zone = 11mm), Flavobacterium meningosepticum CIP 6057(no detected), Pseudomonas aeruginosa CIP A22(Inhibition zone = 18.5mm)."	[Ref.11279030]1mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 ¦Ìl of the peptide solution and placed overnight at 4¡æ to allow the diffusion of the hemolytic agent)	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chaffotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02765	GIWGTALKWGVKLLPKLVGMAQTKKQ	26	"Ponericin-W4 (ants, insects, animals)"	P82426	Not found	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Insecticidal, Antifungal"	Protein level	Not found	Not found	None	"Function: Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae. Has insecticidal and hemolytic activities. 
Tissue specificity: Expressed by the venom gland."	"[Ref.11279030]Gram-positive bacteria: Bacillus cereus CIP 6624a(Inhibition zone = 8.5mm), B. megaterium ATCC 9885b(Inhibition zone = 13.5mm), B. stearothermophilus CIP 675(Inhibition zone = 18mm), B. subtilis ATCC 6623(Inhibition zone = 13mm), Enterococcus faecalis CIP 636(Inhibition zone = 3mm), Lactococcus lactis ssp. cremoris I116(Inhibition zone = 14mm), Streptococcus pyogenes CIP 561(Inhibition zone = 8mm), S. sanguinis CIP 55128(Inhibition zone = 7mm), Listeria ivanovii LMA 94d(Inhibition zone = 10mm), Listeria monocytogenes ATCC 15313(Inhibition zone = 10mm), Micrococcus luteus CIP 5345(Inhibition zone = 12.5mm), Staphylococcus aureus CIP 677(Inhibition zone = 11.5mm), Staphylococcus aureus LMA(Inhibition zone = 13.5mm), S. epidermidis CIP 53134(Inhibition zone = 11.5mm);##Gram-negative bacteria: Escherichia coli(Inhibition zone = 8.5mm), Enterobacter cloacae CIP 6085(Inhibition zone = 16.5mm), Klebsiella pneumoniae CIP 8291(Inhibition zone = 9mm), Proteus mirabilis LMA TP(no detected), Salmonella enterica CIP 813(no detected), Serratia marcescens LMA TP(Inhibition zone = 13mm), Flavobacterium meningosepticum CIP 6057(no detected), Pseudomonas aeruginosa CIP A22(Inhibition zone = 17mm)."	[Ref.11279030]2mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 ¦Ìl of the peptide solution and placed overnight at 4¡æ to allow the diffusion of the hemolytic agent)	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chaffotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02766	FWGALIKGAAKLIPSVVGLFKKKQ	24	"Ponericin-W5 (ants, insects, animals)"	P82427	Belongs to the ponericin-W family	Not found	Pachycondyla goeldii (Ponerine ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Insecticidal, Antifungal"	Protein level	Not found	Not found	None	"Function: Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae. Has insecticidal and hemolytic activities. 
Tissue specificity: Expressed by the venom gland."	"[Ref.11279030]Gram-positive bacteria: Bacillus cereus CIP 6624a(Inhibition zone = 7mm), B. megaterium ATCC 9885b(Inhibition zone = 12mm), B. stearothermophilus CIP 675(Inhibition zone = 17mm), B. subtilis ATCC 6623(Inhibition zone = 13mm), Enterococcus faecalis CIP 636(Inhibition zone = 3mm), Lactococcus lactis ssp. cremoris I116(Inhibition zone = 11mm), Streptococcus pyogenes CIP 561(Inhibition zone = 6.5mm), S. sanguinis CIP 55128(Inhibition zone = 4.5mm), Listeria ivanovii LMA 94d(Inhibition zone = 8mm), Listeria monocytogenes ATCC 15313(Inhibition zone = 6.5mm), Micrococcus luteus CIP 5345(Inhibition zone = 11mm), Staphylococcus aureus CIP 677(Inhibition zone = 7.5mm), Staphylococcus aureus LMA(Inhibition zone = 9mm), S. epidermidis CIP 53134(Inhibition zone = 7.5mm);##Gram-negative bacteria: Escherichia coli(Inhibition zone = 3mm), Enterobacter cloacae CIP 6085(Inhibition zone = 11mm), Klebsiella pneumoniae CIP 8291(Inhibition zone = 6.5mm), Proteus mirabilis LMA TP(no detected), Salmonella enterica CIP 813(no detected), Serratia marcescens LMA TP(Inhibition zone = 11mm), Flavobacterium meningosepticum CIP 6057(Inhibition zone = 5mm), Pseudomonas aeruginosa CIP A22(Inhibition zone = 14mm)."	[Ref.11279030]4mm in test condition against horse erythrocytes (A 12-ml sample of blood agar medium was supplemented with 1 ml of sheep or horse erythrocytes. Wells 5 mm in diameter were filled with 20 ¦Ìl of the peptide solution and placed overnight at 4¡æ to allow the diffusion of the hemolytic agent)	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11279030	J. Biol. Chem. 2001; 276: 17823-17829.	"Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chaffotte A, Dejean A, Rossier J."	"Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii."
DRAMP02772	IDWKKVDWKKVSKKTCKVMLKACKFL	26	"Pilosulin-3a (Allergen Myr p II; Pilosulin-2; ants, insects, animals)"	Q26464	Not found	Not found	Myrmecia pilosula (Jack jumper ant) (Australian jumper ant)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has hemolytic activity.
Tissue specificity: Expressed by the venom gland.
Allergenic properties: Causes an allergic reaction in human.
PTM: Contains one disulfide bond and C-terminal amidation."	No MICs found in DRAMP database	"[Ref.15639237]15% hemolytic activity at 10 ¦ÌM, 40% hemolytic activity at 100 ¦ÌM against human erythrocytes."	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	IgE	15639237##8866004	Toxicon. 2004 Feb;43(2):173-183.##Biochem Mol Biol Int. 1996 Aug;39(5):877-885.	"Davies NW, Wiese MD, Brown SG.##Donovan GR, Street MD, Tetaz T, Smith AI, Alewood D, Alewood P, Sutherland SK, Baldo BA."	Characterisation of major peptides in 'jack jumper' ant venom by mass spectrometry.##Expression of jumper ant (Myrmecia pilosula) venom allergens: post-translational processing of allergen gene products.
DRAMP02773	DVKGMKKAIKGILDCVIEKGYDKLAAKLKKVIQQLWE	37	"Pilosulin 5 (Myr b III; ants, insects, animals)"	A9CM07	Not found	Myrb5	Myrmecia banksi (Jack jumper ant) (Australian jumper ant)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Causes a significant and dose-dependent histamine release, probably by influencing the signal transduction of mast cells through a non-IgE-mediated pathway. This peptide does not have cytotoxic activities.
Subunit structure: Homodimer; disulfide-linked.
Tissue specificity: Expressed by the venom gland.
PTM: Contains one disulfide bond."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18544336##16376960	Arch Biochem Biophys. 2008 Sep 15;477(2):411-416.##Toxicon. 2006 Feb;47(2):208-217.	"Inagaki H, Akagi M, Imai HT, Taylor RW, Wiese MD, Davies NW, Kubo T.##Wiese MD, Chataway TK, Davies NW, Milne RW, Brown SG, Gai WP, Heddle RJ."	"Pilosulin 5, a novel histamine-releasing peptide of the Australian ant, Myrmecia pilosula (Jack Jumper Ant).##Proteomic analysis of Myrmecia pilosula (jack jumper) ant venom."
DRAMP02775	CIANRNGCQPDGSQGNCCSGYCHKEPGWVAGYCR	34	"Antimicrobial peptide Alo-2 (Alo-2; knottin-type peptide; Insects, animals)"	P83652	Belongs to the AMP family	Not found	Acrocinus longimanus (Giant harlequin beetle)	"Antimicrobial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Has antifungal activity against C. glabrata.
Domain: The presence of a disulfide through disulfide knot' structurally defines this protein as a knottin.
PTM: Contains three disulfide bonds 1-18; 8-22; 17-33."	"Fungi: Candida glabrata patient 1 (MIC>64 ?g/mL), C. albicans IHEM 8060 (MIC>64 ?g/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14661954	Biochemistry. 2003 Dec 16;42(49):14434-14442.	"Barbault F, Landon C, Guenneugues M, Meyer JP, Schott V, Dimarcq JL, Vovelle F."	Solution structure of Alo-3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus.
DRAMP02788	SDDEDEEEEEDQPWQLNPNIARGDDGNTRADVNIKRRGENHDFEAGWSKVVDGPDRAKPTWHVGGTFRW	69	"Acaloleptin-A5 (chain of Acaloleptin A; Insects, animals)"	"P81592, Q76K70"	Belongs to the coleoptericin family	Not found	Acalolepta luxuriosa (Udo longhorn beetle)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: Acaloleptin A5 shows antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria, and may also have antifungal activity.
Induction: By bacterial infection. Expression detected 2 hours post-injection, with expression increasing until 48 hours post-injection and remaining considerably high at least until 72 hours post-injection."	"Gram-negative bacteria: Escherichia coli, Aeromonas hydrophila, Erwinia persicinus, Serratia marcescens, Aeromonas hydrophila. "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10077828##19527748	Arch Insect Biochem Physiol. 1999;40(2):88-98.##Dev Comp Immunol. 2009 Oct;33(10):1120-1127. 	"Imamura M, Wada S, Koizumi N, Kadotani T, Yaoi K, Sato R, Iwahana H.##Imamura M, Wada S, Ueda K, Saito A, Koizumi N, Iwahana H, Sato R."	"Acaloleptins A: inducible antibacterial peptides from larvae of the beetle, Acalolepta luxuriosa.##Multipeptide precursor structure of acaloleptin A isoforms, antibacterial peptides from the Udo longicorn beetle, Acalolepta luxuriosa."
DRAMP02790	DHHDGHLGGHQTGHQGGQQGGHLGGQQGGHLGGHQGGQPGGHLGGHQGGIGGTGGQQHGQHGPGTGAGHQGGYKTHGH	78	"Tenecin-3 (Insects, animals)"	Q27270	Not found	Not found	Tenebrio molitor (Yellow mealworm beetle)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Antifungal heat stable protein produced in response to injury. It is active against C.albicans. No antibacterial activity against Gram-positive and Gram-negative bacteria.
Developmental stage: Highest expression in larvae and adult. To a much lesser extent in pupae."	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8573176##PubMed ID is not available	Biochem Biophys Res Commun. 1996 Jan 5;218(1):6-11.##Mol. Cells 1995;5:287-292.	"Lee YJ, Chung TJ, Park CW, Hahn Y, Chung JH, Lee BL, Han DM, Jung YH, Kim S, Lee Y.##Jung HY, Park BY, Lee DK, Hahn Y, Chung JH, Han DM, Moon HJ, Lee BL, Lee Y."	Structure and expression of the tenecin 3 gene in Tenebrio molitor.##Biochemical and molecular characterization of an antifungal protein from Tenebrio molitor larvae.
DRAMP02792	ELPKLPDDKVLIRSRSNCPKGKVWNGFDCKSPFAFS	36	"Scarabaecin, major form (Insects, animals)"	Q86SC0	Not found	scar	Oryctes rhinoceros (Coconut rhinoceros beetle)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Combine helix and strand structure	"The solution structure consists of a two-stranded antiparallel beta-sheet connected by a type-I beta-turn after a short helical turn. All secondary structures and a conserved disulfide bond are located in the C-terminal half of the peptide, residues 18-36. Overall folding is stabilized by a combination of a disulfide bond, seven hydrogen bonds, and numerous hydrophobic interactions.(Ref.2)"	1IYC resolved by NMR.	Comment: No comments found on DRAMP database	"Fungi: P. oryzae (IC50=16 ?M), R. solani (IC50=32 ?M), Botrytis cinerea (IC50=4 ?M), S.tritici (IC50=16 ?M), P. syringae pv.mori S6804 (IC50=25 ?M); And Staphylococcus aureus, B. bassiana (weak activity)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	12859949##12676931	Biochem Biophys Res Commun. 2003 Jul 25;307(2):261-266.##J Biol Chem. 2003 Jun 20;278(25):22820-22827.	"Tomie T, Ishibashi J, Furukawa S, Kobayashi S, Sawahata R, Asaoka A, Tagawa M, Yamakawa M.##Hemmi H, Ishibashi J, Tomie T, Yamakawa M."	"Scarabaecin, a novel cysteine-containing antifungal peptide from the rhinoceros beetle, Oryctes rhinoceros.##Structural basis for new pattern of conserved amino acid residues related to chitin-binding in the antifungal peptide from the coconut rhinoceros beetle Oryctes rhinoceros."
DRAMP02807	DCCRKPFRKHCWDCTAGTPYYGYSTRNIFGCTC	33	"Mytimycin (molluscas, animals)"	P81614	Not found	Not found	Mytilus edulis (Blue mussel)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Neurospora crassa, Fusarium culmorum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8702979	J Biol Chem. 1996 Sep 6;271(36):21808-21813.	"Charlet M, Chernysh S, Philippe H, Hetru C, Hoffmann JA, Bulet P."	"Innate immunity. Isolation of several cysteine-rich antimicrobial peptides from the blood of a mollusc, Mytilus edulis."
DRAMP02810	QEAQSVACTSYYCSKFCGSAGCSLYGCYLLHPGKICYCLHCSR	43	Myticin C 	No entry found	Not found	Not found	Mytilus galloprovincialis (Mediterranean mussel)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17628673	Dev Comp Immunol. 2008;32(3):213-226.	"Pallavicini A, Costa Mdel M, Gestal C, Dreos R, Figueras A, Venier P, Novoa B."	High sequence variability of myticin transcripts in hemocytes of immune-stimulated mussels suggests ancient host-pathogen interactions.
DRAMP18235	LLEL	4	Gageopeptide D(Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antifungal, Antibacterial, Anti-Gram+, Anti-Gram-"		Not found	"Leu-Leu-Glu-Leu-3-beta-hydroxy-9,11-dimethyltetradecanoic acid"	None	"Non-cytotoxic antifungal agents. It was revealed that compounds 1 and 2 exhibited stronger antifungal activity than 3 and 4. Compounds 1 and 2 were structurally different from compounds 3 and 4 in terms of having less side chains in the fatty acid units, suggesting that the side chain length and the additional methyl group in the aliphatic chain are important for antifungal activity. These compounds also showed potent antimicrobial activity against Gram positive and Gram negative bacteria with MIC values of 0.04?0.08 uM."	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2485741	Yan Ke Xue Bao. 1989 Jun;5(1-2):32-5.	"Lin N, Gong XM, Xie QJ, Shao MR."	Study in cytotoxicity of gentamycin to corneal epithelium and endothelium in tissue culture.
DRAMP02816	RQKDKRPYSERKNQYTGPQFLYPPERIPP	29	Lumbrican	No entry found	Not found	Not found	Lumbricus rubellus (humus earthworm)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis ATCC 62037, Staphylococcus aureus ATCC 15752, Streptococcus mutans ATCC 25175;##Gram-negative bacteria: Escherichia coli ATCC 27325, Pseudomonas putida ATCC 17426, Serratia sp. ATCC 21074.##Fungi: Candida albicans ATCC 10231, Cryptococcus neoformans ATCC 34881, Saccharomyces cerevisiae ATCC 44774."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9784609	Biochim Biophys Acta. 1998 Oct 22;1408(1):67-76.	"Cho JH, Park CB, Yoon YG, Kim SC."	"Lumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization."
DRAMP02822	YGPGDGHGGGHGGGHGGGHGNGQGGGHGHGPGGGFGGGHGGGHGGGGRGGGGSGGGGSPGHGAGGGYPGGHGGGHHGGYQTHGY	84	Holotricin-3 (Gly-rich; His-rich; invertebrate defensin; animals)	Q25055	Not found	Not found	Holotrichia diomphalia (Korean black chafer)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Has antifungal activity against C. albicans.	Yeast: Candida ablicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8535393	Biol. Pharm. Bull. 1995; 18:1049-1052.	"Lee S.Y, Moon H.J, Kurata S, Natori S, Lee B.L."	Purification and cDNA cloning of an antifungal protein from the hemolymph of Holotrichia diomphalia larvae.
DRAMP02831	MLTDLECAINSLIDVYHKYSLKKGNYHAVYRDDLKQLLETECPKFMKKKDADTWFKELDINQDGGINFEEFLVLVIKVGLEAHEEIHKE	89	"Protein S100-A8 (Calgranulin-A; MRP-8; mammals, animals)"	"P28782, Q2NKR8"	Belongs to the S-100 family	S100A8	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn2+ which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect.
Tissue specificity: Found essentially in phagocytic cells.
Miscellaneous: Binds two calcium ions per molecule with an affinity similar to that of the S100 proteins (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Metal-binding	1610833##8505358	Biochemistry. 1992 Jun 30;31(25):5898-5905.##J Cell Sci. 1993 Feb;104 ( Pt 2):237-247.	"Dianoux AC, Stasia MJ, Garin J, Gagnon J, Vignais PV.##Tang TK, Hong TM, Lin CY, Lai ML, Liu CH, Lo HJ, Wang ME, Chen LB, Chen WT, Ip W, et al."	"The 23-kilodalton protein, a substrate of protein kinase C, in bovine neutrophil cytosol is a member of the S100 family.##Nuclear proteins of the bovine esophageal epithelium. I. Monoclonal antibody W2 specifically reacts with condensed nuclei of differentiated superficial cells."
DRAMP02834	SDEKASPDKHHRFSLSRYAKLANRLANPKLLETFLSKWIGDRGNRSVK	48	"Seminalplasmin (Calcium transport inhibitor; Peptide YY-2; mammals, animals)"	P06833 	Not found	PYY2	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Function: Inhibits calcium transport into spermatozoa; it does not bind directly to calcium. Binds to calmodulin. Inhibits the growth of microorganisms. Seem to act as an antibiotic by permeabilizing the bacterial membrane.	"Gram-negative bacterium: Escherichia coli.##Fungi: Saccharomyces cerevisiae, Candida ablicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Does not bind directly to calcium. It binds to calmodulin in the presence of Ca2+.	16453469##2334517##3863108	EMBO J. 1983;2(7):1159-1163.##Biol Chem Hoppe Seyler. 1990 Feb;371(2):111-116.##Proc Natl Acad Sci U S A. 1985 Oct;82(19):6490-6491.	"Theil R, Scheit KH.##Krauhs E, Preuss KD, Scheit KH.##Lewis RV, Agustin JS, Kruggel W, Lardy HA."	"Amino acid sequence of seminalplasmin, an antimicrobial protein from bull semen.##Functional properties of peptides derived from seminalplasmin: binding to monospecific anti-seminalplasmin immunoglobulins G and calmodulin.##The structure of caltrin, the calcium-transport inhibitor of bovine seminal plasma."
DRAMP18233	LLLE	4	Gageopeptide B(Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antifungal, Antibacterial, Anti-Gram+, Anti-Gram-"		Not found	Leu-Leu-Leu-OMeGlu-3-beta-hydroxy-12-methyltetradecanoic acid	None	"Non-cytotoxic antifungal agents. It was revealed that compounds 1 and 2 exhibited stronger antifungal activity than 3 and 4. Compounds 1 and 2 were structurally different from compounds 3 and 4 in terms of having less side chains in the fatty acid units, suggesting that the side chain length and the additional methyl group in the aliphatic chain are important for antifungal activity. These compounds also showed potent antimicrobial activity against Gram positive and Gram negative bacteria with MIC values of 0.04?0.08 uM."	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2485741	Yan Ke Xue Bao. 1989 Jun;5(1-2):32-5.	"Lin N, Gong XM, Xie QJ, Shao MR."	Study in cytotoxicity of gentamycin to corneal epithelium and endothelium in tissue culture.
DRAMP18234	LLEL	4	Gageopeptide C(Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antifungal, Antibacterial, Anti-Gram+, Anti-Gram-"		Not found	"Leu-Leu-Glu-Leu-3-beta-hydroxy-9,11-dimethyltridecanoic acid"	None	"Non-cytotoxic antifungal agents. It was revealed that compounds 1 and 2 exhibited stronger antifungal activity than 3 and 4. Compounds 1 and 2 were structurally different from compounds 3 and 4 in terms of having less side chains in the fatty acid units, suggesting that the side chain length and the additional methyl group in the aliphatic chain are important for antifungal activity. These compounds also showed potent antimicrobial activity against Gram positive and Gram negative bacteria with MIC values of 0.04?0.08 uM."	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2485741	Yan Ke Xue Bao. 1989 Jun;5(1-2):32-5.	"Lin N, Gong XM, Xie QJ, Shao MR."	Study in cytotoxicity of gentamycin to corneal epithelium and endothelium in tissue culture.
DRAMP02847	QAEESNLQSLVSQYFQTVADYGKDLVEKAKGSELQTQAKAYFEKTQEELTPFFKKAGTDLLNFLSSFIDPKKQPATR	77	"Apolipoprotein A-II (Antimicrobial peptide BAMP-1; mammals, animals)"	"P81644, Q2NKV9"	Belongs to the apolipoprotein A2 family	APOA2	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function:May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Has antimicrobial activity."	Escherichia coli and yeasts.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9538260	J Biochem. 1998 Apr;123(4):675-679.	"Motizuki M, Itoh T, Yamada M, Shimamura S, Tsurugi K."	"Purification, primary structure, and antimicrobial activities of bovine apolipoprotein A-II."
DRAMP02848	QAEESNLQSLVSQYFQTVADYGKDLVEKAKGSELQTQAKAYFEKTQEELTPFFKKAGTDLLNFLSSFIDPKKQPAT	76	"Apolipoprotein A-II(1-76)(mammals, animals)"	"P81644, Q2NKV9"	Belongs to the apolipoprotein A2 family	APOA2	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function:May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Has antimicrobial activity."	Escherichia coli and yeasts.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9538260	J Biochem. 1998 Apr;123(4):675-679.	"Motizuki M, Itoh T, Yamada M, Shimamura S, Tsurugi K."	"Purification, primary structure, and antimicrobial activities of bovine apolipoprotein A-II."
DRAMP01356	FLGGLMKAFPALICAVTKKC	20	"Ranalexin-1Ca (Ranatuerin 1Ca; Frogs, amphibians, animals)"	P82876	Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.	Not found	Rana clamitans (Green frog) (Lithobates clamitans)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against Gram-positive, Gram-negative bacteria and fungi. 
Tissue specificity: Expressed by the skin glands."	[Ref.10822101] Gram-positive bacterium: Staphylococcus aureus (MIC=17 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=4 ¦ÌM).##Yeast: Candida albicans (MIC=14 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10822101	Peptides. 2000 Apr;21(4):469-476.	"Halverson T, Basir YJ, Knoop FC, Conlon JM."	Purification and characterization of antimicrobial peptides from the skin of the North American green frog Rana clamitans.
DRAMP02879	NPVSCVRNKGICVPIRCPGNMKQIGTCVGRAVKCCR	36	"Tracheal antimicrobial peptide (mammals, animals)"	No entry found	Not found	Not found	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida ablicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8506305	Proc Natl Acad Sci U S A. 1993 May 15;90(10):4596-600.	"Diamond G, Jones DE, Bevins CL."	Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene.
DRAMP02881	NPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCR	36	"Antimicrobial protein exons 1-2 (mammals, animals)"	No entry found	Not found	Not found	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Antifungal"	Not found	dulsulfide-bond link	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida ablicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8506305	Proc Natl Acad Sci U S A. 1993 May 15;90(10):4596-600.	"Diamond G, Jones DE, Bevins CL."	Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene.
DRAMP02883	MIQIKFLCLFLAIMTIVVLDSNVAEARDCLSGTFKGPCWAWSGEKCRRLCIEEGRVSGHCSGGSKCWCEGC	71	Drosomycin-like A (Predicted)	Q95NH5	Not found	Drsl-B	Drosophila triauraria	"Antimicrobial, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11707335	Gene. 2001 Oct 31;278(1-2):177-184.	"Daibo S, Kimura MT, Goto SG."	Upregulation of genes belonging to the drosomycin family in diapausing adults of Drosophila triauraria.
DRAMP02884	DCLSGRYRGSCAVWHRKKCVDICQREGRTSGHCSPSLKCWCEGC	44	Drosomycin-like C	Q86GH7	Not found	Drsl1	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16824706	Gene. 2006 Sep 1;379:26-32.	"Yang WY, Wen SY, Huang YD, Ye MQ, Deng XJ, Han D, Xia QY, Cao Y."	Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster.
DRAMP02885	MVQMIFLFAILAVMTIVLMEANTVLARDCLSGTFGGPCWAWSGEKCRRLCIEEGHVSGHCSGAMKCWCEGC	71	Drosomycin-like 3 (Drosomycin-like E; Drosomycin-like G; Predicted)	Q8IRD7	Not found	Drsl3	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16824706	Gene. 2006 Sep 1;379:26-32.	"Yang WY, Wen SY, Huang YD, Ye MQ, Deng XJ, Han D, Xia QY, Cao Y."	Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster.
DRAMP02886	MQIKFLYLFLAVMTIFILGAKEADADCLSGRYGGPCAVWDNETCRRVCKEEGRSSGHCSPSLKCWCEGC	69	Drosomycin-like 5 (Drosomycin-like E; Drosomycin-like G; Predicted)	Q9VZR2	Not found	Drsl5	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16824706	Gene. 2006 Sep 1;379:26-32.	"Yang WY, Wen SY, Huang YD, Ye MQ, Deng XJ, Han D, Xia QY, Cao Y."	Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster.
DRAMP02887	MEIKFLIVLSAVLMIIFLGAEESHADCLSGRYRGSCAVWHRKKCVDICQREGRTSGHCSPSLKCWCEGC	69	Dro1 protein (Drosomycin-like 1; Drosomycin-like C1; Predicted)	"Q9VZQ5, C9QPF6"	Not found	Drsl1	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16824706	Gene. 2006 Sep 1;379:26-32.	"Yang WY, Wen SY, Huang YD, Ye MQ, Deng XJ, Han D, Xia QY, Cao Y."	Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster.
DRAMP02888	MVQIKFLFVFLAVMTIVVLAANMADADCLSGKYKGPCAVWDNEMCRRICKEEGHISGHCSPSLKCWCEGC	70	Dro2 protein (Drosomycin 2; Drosomycin-like 2; Drosomycin-like D; Drosomycin-like H; Predicted)	"Q7YXH9, Q9VZR3"	Not found	Drsl2	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16824706	Gene. 2006 Sep 1;379:26-32.	"Yang WY, Wen SY, Huang YD, Ye MQ, Deng XJ, Han D, Xia QY, Cao Y."	Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster.
DRAMP02889	MAQIKGLFALLAVVTIVLMVANSASAVDCPSGRFSGPCWAWDGEQCRRLCREEGRVSGHCSASLKCWCEQC	71	Dro4 protein (Drosomycin 4; Drosomycin-like 4; Drosomycin-like F; Predicted)	Q8IRD6	Not found	Drsl4	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16824706	Gene. 2006 Sep 1;379:26-32.	"Yang WY, Wen SY, Huang YD, Ye MQ, Deng XJ, Han D, Xia QY, Cao Y."	Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster.
DRAMP02890	MMQIKFLFTFLALLMMVILGAKEADADCLSGRYRGPCAVWDNETCRRVCREEGRGRVSGHCSARLQCWCEGC	72	Dro6 protein (Drosomycin-like 6; Drosomycin-like D; Drosomycin-like I; Predicted)	Q9VZQ4	Not found	Drsl6	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16824706	Gene. 2006 Sep 1;379:26-32.	"Yang WY, Wen SY, Huang YD, Ye MQ, Deng XJ, Han D, Xia QY, Cao Y."	Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster.
DRAMP02896	MFTLKKSLLLLFFLGTINLSLCEQERNADEEERRDDSDKRDVEVEKRFLSTLLKVAFKVVPTLFCPITKKC	71	Brevinin-1-AJ1 antimicrobial peptide	K7Z430	Not found	Not found	Amolops jingdongensis (Chinese torrent frog)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	"[Ref.22828809] 7.62% hemolytic activity at 25 ¦Ìg/ml,24.58% hemolytic activity at 50 ¦Ìg/ml, 83.05% hemolytic activity at 100 ¦Ìg/ml, 87.65% hemolytic activity at 200 ¦Ìg/ml against rabbit red blood cells"	Cyclic	Free	Cyclization (Cys65 and Cys71)	Disulfide bond between Cys65 and Cys71.	L	No cytotoxicity information found	Not found	22828809	Amino Acids. 2012 Jul 25	"He X, Yang S, Wei L, Liu R, Lai R, Rong M."	"Antimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis."
DRAMP02935	RRWCFRVCYKGFCYRKCR	18	"Polyphemusin-2 (Polyphemusin II; crabs, Arthropods, animals)"	P14216	Belongs to the tachyplesin/polyphemusin family	Not found	Limulus polyphemus (Atlantic horseshoe crab)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Significantly inhibits the growth of Gram-negative and Gram-positive bacteria.
Tissue specificity: Hemocytes.
PTM: Contains two disulfide bonds 4-17; 8-13."	Yeast: Candida albicans M9.	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Amidation	"Disulfide bond between Cys4 and Cys17,Cys8 and Cys13."	L	No cytotoxicity information found	Not found	2514185##15134657	J Biochem. 1989 Oct;106(4):663-668.##Biochim Biophys Acta. 2004 May 6;1698(2):239-250.	"Miyata T, Tokunaga F, Yonega T, Yoshikawa K, Iwanaga S, Niwa M, Takao T, Shimonishi Y.##Powers J.P, Rozek A, Hancock R.E."	"Antimicrobial peptides, isolated from horseshoe crab hemocytes, tachyplesin II, and polyphemusins I and II: chemical structures and biological activity.##Structure-activity relationships for the beta-hairpin cationic antimicrobial peptide polyphemusin I."
DRAMP02936	NPLIPAIYIGATVGPSVWAYLVALVGAAAVTAANIRRASSDNHSCAGNRGWCRSKCFRHEYVDTYYSAVCGRYFCCRSR	79	"Big defensin (crabs, Arthropods, animals)"	P80957	Belongs to the big defensin family	Not found	Tachypleus tridentatus (Japanese horseshoe crab)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Combine helix and strand structure	Not found	2RNG resolved by NMR.	"Function: Significantly inhibits the growth of Gram-negative and Gram-positive bacteria and fungi in vitro.
Tissue specificity: Expressed in all tissues examined, including hemocytes, heart, hepatopancreas, stomach, intestine and skeletal muscle.
PTM: Contains three disulfide bonds."	"Gram-negative bacteria: Escherichia coli 09:K39 (IC50=5 ?g/ml), Salmonella typhimurium LT2 (IC50=20 ?g/ml), S. minnesota R595 (IC50=1.3 ?g/ml), Klebsiella pneumoniae (IC50>10 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus (IC50<2.5 ?g/ml).##Yeast: Candida albicans (IC50>20 ?g/ml)(Ref.1).##Note: Washed with a phosphate buffered saline (PBS, pH 7.0)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipopolysaccharide (LPS)-binding	8586631##18785751	J Biochem. 1995 May;117(5):1131-1137.##Biochemistry. 2008 Oct 7;47(40):10611-9.	"Saito T, Kawabata S, Shigenaga T, Takayenoki Y, Cho J, Nakajima H, Hirata M, Iwanaga S.##Kouno T, Fujitani N, Mizuguchi M, Osaki T, Nishimura S, Kawabata S, Aizawa T, Demura M, Nitta K, Kawano K."	"A novel big defensin identified in horseshoe crab hemocytes: isolation, amino acid sequence, and antibacterial activity.##A novel beta-defensin structure: a potential strategy of big defensin for overcoming resistance by Gram-positive bacteria."
DRAMP02937	YLAFRCGRYSPCLDDGPNVNLYSCCSFYNCHKCLARLENCPKGLHYNAYLKVCDWPSKAGCTSVNKECHLWKT	73	"Tachycitin (crabs, Arthropods, animals)"	P91818	Not found	Not found	Tachypleus tridentatus (Japanese horseshoe crab)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Beta strand	Not found	1DQC resolved by NMR.	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Staphylococcus aureus (IC50=56 ?g/ml);##Gram-negative bacteria: Escherichia coli 363 (IC50=33 ?g/ml), Escherichia coli B (IC50=2 ?g/ml), Salmonella typhimurium LT2 (IC50=44 ?g/ml), S. minnesota R595 (IC50=41 ?g/ml), Klebsiella pneumoniae (IC50=32 ?g/ml).##Yeast: Candida albicans (IC50=52 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	9010778##10770921	J Biochem. 1996 Dec;120(6):1253-1260.##J Biol Chem. 2000 Jun 16;275(24):17929-17932.	"Kawabata S, Nagayama R, Hirata M, Shigenaga T, Agarwala KL, Saito T, Cho J, Nakajima H, Takagi T, Iwanaga S.##Suetake T, Tsuda S, Kawabata S, Miura K, Iwanaga S, Hikichi K, Nitta K, Kawano K."	"Tachycitin, a small granular component in horseshoe crab hemocytes, is an antimicrobial protein with chitin-binding activity.##Chitin-binding proteins in invertebrates and plants comprise a common chitin-binding structural motif."
DRAMP18230	LLLE	4	Gageotetrin B  (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antifungal, Antibacterial, Anti-Gram+, Anti-Gram-"		Not found	Leu-Leu-Leu-OMeGlu-3-hydroxy-11-methyltridecanoic acid (HTDA)	None	Noncytotoxic Antimicrobial Linear Lipopeptides	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	24502521	Org Lett. 2014 Feb 7;16(3):928-31. 	"Tareq FS, Lee MA, Lee HS, Lee YJ, Lee JS, Hasan CM, Islam MT, Shin HJ."	"Gageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis."
DRAMP18231	LLLE	4	Gageotetrin C (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antifungal, Antibacterial, Anti-Gram+, Anti-Gram-"		Not found	"Leu-Leu-Leu-Glu-3-hydroxy-8,10-dimethyldodecanoic acid (HDDA)"	None	Noncytotoxic Antimicrobial Linear Lipopeptides	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	24502521	Org Lett. 2014 Feb 7;16(3):928-31. 	"Tareq FS, Lee MA, Lee HS, Lee YJ, Lee JS, Hasan CM, Islam MT, Shin HJ."	"Gageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis."
DRAMP18232	LLEL	4	Gageopeptide A(Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antifungal, Antibacterial, Anti-Gram+, Anti-Gram-"		Not found	Leu-Leu-Glu-Leu-3-beta-hydroxy-11-methyltridecanoic acid	None	"Non-cytotoxic antifungal agents. It was revealed that compounds 1 and 2 exhibited stronger antifungal activity than 3 and 4. Compounds 1 and 2 were structurally different from compounds 3 and 4 in terms of having less side chains in the fatty acid units, suggesting that the side chain length and the additional methyl group in the aliphatic chain are important for antifungal activity. These compounds also showed potent antimicrobial activity against Gram positive and Gram negative bacteria with MIC values of 0.04?0.08 uM."	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2485741	Yan Ke Xue Bao. 1989 Jun;5(1-2):32-5.	"Lin N, Gong XM, Xie QJ, Shao MR."	Study in cytotoxicity of gentamycin to corneal epithelium and endothelium in tissue culture.
DRAMP02939	RWCFRVCYRGICYRKCR	17	"Tachyplesin-2 (Tachyplesin II; crabs, Arthropods, animals)"	P14214	Belongs to the tachyplesin/polyphemusin family	Not found	Tachypleus tridentatus (Japanese horseshoe crab)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Bridge	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans M9.	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Amidation (Arg17)	"Disulfide bond between Cys3 and Cys16,Cys7 and Cys12."	L	No cytotoxicity information found	Not found	2514185	J Biochem. 1989 Oct;106(4):663-668.	"Miyata T, Tokunaga F, Yonega T, Yoshikawa K, Iwanaga S, Niwa M, Takao T, Shimonishi Y."	"Antimicrobial peptides, isolated from horseshoe crab hemocytes, tachyplesin II, and polyphemusins I and II: chemical structures and biological activity."
DRAMP02941	YSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRF	44	"Tachystatin-A1 (crabs, Arthropods, animals)"	P0C1Z7	Not found	Not found	Tachypleus tridentatus (Japanese horseshoe crab)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	None	"Function: Exhibits stronger antimicrobial activity against the Gram-positive bacterium S. aureus and fungi C. albicans and P. pastoris than Gram-negative bacterium E. coli. Binds to chitin (8.4 ?M are required to obtain 50% of binding). Does not cause hemolysis on sheep erythrocytes. Has no blocking activity on the P-type calcium channel.
Tissue specificity: Granular hemocytes, small secretory granules.
PTM: Contains three disulfide bonds (By similarity)."	"Gram-negative bacterium: Escherichia coli (IC50=25 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus (IC50=4.2 ?g/ml).##Fungi: Candida albicans (IC50=3.0 ?g/ml), Pichia pastoris (IC50=0.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	10473569	J Biol Chem. 1999 Sep 10;274(37):26172-26178.	"Osaki T, Omotezako M, Nagayama R, Hirata M, Iwanaga S, Kasahara J, Hattori J, Ito I, Sugiyama H, Kawabata S."	"Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins."
DRAMP02942	YSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRY	44	"Tachystatin-A2 (crabs, Arthropods, animals)"	Q9U8X3	Not found	Not found	Tachypleus tridentatus (Japanese horseshoe crab)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Beta strand	Not found	1CIX resolved by NMR.	"Function: Exhibits stronger antimicrobial activity against the Gram-positive bacterium S. aureus and fungi C. albicans and P. pastoris than Gram-negative bacterium E. coli. Binds to chitin (8.4 ?M are required to obtain 50% of binding). Does not cause hemolysis on sheep erythrocytes. Has no blocking activity on the P-type calcium channel.
Tissue specificity: Granular hemocytes, small secretory granules.
PTM: Contains three disulfide bonds."	"Gram-positive bacterium: Staphylococcus aureus (IC50=4.2 ?g/ml);##Gram-negative bacterium: Escherichia coli (IC50=25 ?g/ml).##Fungi: Candida albicans (IC50=3.0 ?g/ml), Pichia pastoris (IC50=0.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	10473569##11959852	J Biol Chem. 1999 Sep 10;274(37):26172-26178.##J Biol Chem. 2002 Jun 28;277(26):23651-23657.	"Osaki T, Omotezako M, Nagayama R, Hirata M, Iwanaga S, Kasahara J, Hattori J, Ito I, Sugiyama H, Kawabata S.##Fujitani N, Kawabata S, Osaki T, Kumaki Y, Demura M, Nitta K, Kawano K."	"Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins.##Structure of the antimicrobial peptide tachystatin A."
DRAMP02943	YVSCLFRGARCRVYSGRSCCFGYYCRRDFPGSIFGTCSRRNF	42	"Tachystatin-B1 (crabs, Arthropods, animals)"	P0C1Z8	Not found	Not found	Tachypleus tridentatus (Japanese horseshoe crab)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Beta strand	Not found	2DCV resolved by NMR.	"Function: Exhibits stronger antimicrobial activity against the Gram-positive bacterium S. aureus and fungi C. albicans and P. pastoris than Gram-negative bacterium E. coli. Binds to chitin (4.3 ?M are required to obtain 50% of binding). Does not cause hemolysis on sheep erythrocytes. Has no blocking activity on the P-type calcium channel.
Tissue specificity: Granular hemocytes, small secretory granules.
Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin."	"Gram-positive bacterium: Staphylococcus aureus (IC50=7.4 ?g/ml).##Fungi: Candida albicans (IC50=3.0 ?g/ml), Pichia pastoris (IC50=0.1 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	10473569##17394123	J Biol Chem. 1999 Sep 10;274(37):26172-26178.##J Pept Sci. 2007 Apr;13(4):269-279.	"Osaki T, Omotezako M, Nagayama R, Hirata M, Iwanaga S, Kasahara J, Hattori J, Ito I, Sugiyama H, Kawabata S.##Fujitani N, Kouno T, Nakahara T, Takaya K, Osaki T, Kawabata S, Mizuguchi M, Aizawa T, Demura M, Nishimura S, Kawano K."	"Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins.##The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif."
DRAMP02944	YITCLFRGARCRVYSGRSCCFGYYCRRDFPGSIFGTCSRRNF	42	"Tachystatin-B2 (crabs, Arthropods, animals)"	P0C1Z9	Not found	Not found	Tachypleus tridentatus (Japanese horseshoe crab)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Beta strand	Not found	2DCW resolved by NMR.	"Function: Exhibits stronger antimicrobial activity against the Gram-positive bacterium S. aureus and fungi C. albicans and P. pastoris than Gram-negative bacterium E. coli. Binds to chitin (4.3 ?M are required to obtain 50% of binding). Does not cause hemolysis on sheep erythrocytes. Has no blocking activity on the P-type calcium channel.
Tissue specificity: Granular hemocytes, small secretory granules.
Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin."	"Gram-positive bacterium: Staphylococcus aureus (IC50=7.4 ?g/ml).##Fungi: Candida albicans (IC50=3.0 ?g/ml), Pichia pastoris (IC50=0.1 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	10473569##17394123	J Biol Chem. 1999 Sep 10;274(37):26172-26178.##J Pept Sci. 2007 Apr;13(4):269-279.	"Osaki T, Omotezako M, Nagayama R, Hirata M, Iwanaga S, Kasahara J, Hattori J, Ito I, Sugiyama H, Kawabata S.##Fujitani N, Kouno T, Nakahara T, Takaya K, Osaki T, Kawabata S, Mizuguchi M, Aizawa T, Demura M, Nishimura S, Kawano K."	"Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins.##The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif."
DRAMP02945	DYDWSLRGPPKCATYGQKCRTWSPPNCCWNLRCKAFRCRPR	41	"Tachystatin-C (crabs, Arthropods, animals)"	P0C200	Not found	Not found	Tachypleus tridentatus (Japanese horseshoe crab)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	None	"Causes hemolysis on sheep erythrocytes, probably by forming ion-permeable pores."	"Gram-negative bacterium: Escherichia coli (IC50=1.2 ?g/ml);##Gram-positive bacterium: Staphylococcus aureus (IC50=0.8 ?g/ml).##Fungi: Candida albicans (IC50=0.9 ?g/ml), Pichia pastoris (IC50=0.3 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Chitin-binding	10473569	J Biol Chem. 1999 Sep 10;274(37):26172-26178.	"Osaki T, Omotezako M, Nagayama R, Hirata M, Iwanaga S, Kasahara J, Hattori J, Ito I, Sugiyama H, Kawabata S."	"Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins."
DRAMP18228	LLDVLLE	7	Gageostatin C (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	"Leu-Leu-Asp-Val-Leu-Leu-Glu-(E)-7,9-dimethylundec-2-enoic acid"	None	"surfactin like heptapeptides, cytotoxic. It is noteworthy that these compounds 1"	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	24492520	Mar Drugs. 2014 Jan 31;12(2):871-85. 	"Tareq FS, Lee MA, Lee HS, Lee JS, Lee YJ, Shin HJ."	"Gageostatins A-C, antimicrobial linear lipopeptides from a marine Bacillus subtilis."
DRAMP18229	LE	2	Gageotetrin A (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antifungal, Antibacterial, Anti-Gram+, Anti-Gram-"		Not found	Leu-Glu-3-hydroxy-11-methyltridecanoic acid (HTDA)	None	Noncytotoxic Antimicrobial Linear Lipopeptides	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	24502521	Org Lett. 2014 Feb 7;16(3):928-31. 	"Tareq FS, Lee MA, Lee HS, Lee YJ, Lee JS, Hasan CM, Islam MT, Shin HJ."	"Gageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis."
DRAMP02971	RGGRLCYCRRRFCICV	16	"Protegrin-2 (Protegrin 2; PG-2; pigs, mammals, animals)"	P32195	Belongs to the cathelicidin family	NPG2	Sus scrofa (Pig)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	2MUH resolved by NMR.	"Function: Microbicidal activity. Active against E.coli, Listeria monocytogenes and C.albicans, in vitro.
PTM: Contains two disulfide bonds 6-15; 8-13 and Valine amide at V16."	Gram-positive bacterium: Listeria moncyrogenes strain EGD (MIC>25 ?g/ml);##Gram-negative bacterium: Escherichia coli ML-35 (MIC>25 ?g/ml).##Yeast: Candida albicans strain 820 (MIC>25 ?g/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8335113##8250892	FEBS Lett. 1993 Jul 26;327(2):231-236.##Biochem Biophys Res Commun. 1993 Nov 15;196(3):1363-1368.	"Kokryakov VN, Harwig SS, Panyutich EA, Shevchenko AA, Aleshina GM, Shamova OV, Korneva HA, Lehrer RI.##Storici P, Zanetti M."	Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins.##A novel cDNA sequence encoding a pig leukocyte antimicrobial peptide with a cathelin-like pro-sequence.
DRAMP02972	RGGGLCYCRRRFCVCVGR	18	"Protegrin-3 (Protegrin 3; PG-3; pigs, mammals, animals)"	P32196	Belongs to the cathelicidin family	NPG3	Sus scrofa (Pig)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Bridge	Not found	2MZ6 resolved by NMR.	"Function: Microbicidal activity. Active against E.coli, Listeria monocytogenes and C.albicans, in vitro.
PTM: Probablely contains two disulfide bonds 6-15; 8-13 and Arginine amide at R18."	Gram-positive bacterium: Listeria moncyrogenes strain EGD;##Gram-negative bacterium: Escherichia coli ML-35.##Yeast: Candida albicans strain 820.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8335113	FEBS Lett. 1993 Jul 26;327(2):231-236.	"Kokryakov VN, Harwig SS, Panyutich EA, Shevchenko AA, Aleshina GM, Shamova OV, Korneva HA, Lehrer RI."	Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins.
DRAMP02973	RGGRLCYCRGWICFCVGR	18	"Protegrin-4 (Protegrin 4; PG-4; pigs, mammals, animals)"	P49933	Belongs to the cathelicidin family	NPG4	Sus scrofa (Pig)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Bridge	Not found	None	"Function: Microbicidal activity (By similarity).
PTM: Contains two disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8013647##12705830	FEBS Lett. 1994; 346: 285-288.##ochemistry. 2003 Apr 29;42(16):4669-4680.	"Zhao C, Liu L, Lehrer RI.##Yang Y, Sanchez JF, Strub MP, Brutscher B, Aumelas A."	Identification of a new member of the protegrin family by cDNA cloning.##NMR structure of the cathelin-like domain of the protegrin-3 precursor.
DRAMP02974	RGGRLCYCRPRFCVCVGR	18	"Protegrin-5 (Protegrin 5; PG-5; pigs, mammals, animals)"	P49934	Belongs to the cathelicidin family	NPG5	Sus scrofa (Pig)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Bridge	Not found	None	"Function: Microbicidal activity (By similarity).
PTM: Contains two disulfide bonds (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7628604	FEBS Lett. 1995 Jul 17;368(2):197-202.	"Zhao C, Ganz T, Lehrer RI."	The structure of porcine protegrin genes.
DRAMP02985	RRCICTTRTCRFPYRRLGTCLFQNRVYTFCC	31	"Neutrophil cationic peptide 2 (CP-2; GNCP-2; pigs, mammals, animals)"	"P49112, Q9R0Z5"	Belongs to the alpha-defensin family	Not found	Cavia porcellus (Guinea pig)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral"	Homology	Bridge	Not found	None	"Function: Has antibiotic, anti-fungi and antiviral activity.
PTM: Contains three disulfide bonds (By similarity)."	Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Staphylococcus aureus.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8173076##10738945	DNA Seq. 1993;4(2):123-128.##Inflamm Res. 2000 Feb;49(2):73-79.	"Nagaoka I, Nonoguchi A, Yamashita T.##Nagaoka I, Hirota S, Yomogida S, Ohwada A, Hirata M."	Cloning and characterization of the guinea pig neutrophil cationic peptide-1 and -2 genes.##Synergistic actions of antibacterial neutrophil defensins and cathelicidins.
DRAMP02986	RRCICTTRTCRFPYRRLGTCIFQNRVYTFCC	31	"Neutrophil cationic peptide 1 (GPNP; Antiviral defensin; pigs, mammals, animals)"	"Q64365, P11478"	Belongs to the alpha-defensin family	Not found	Cavia porcellus (Guinea pig)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral"	Protein level	Bridge	Not found	None	"Function: Has antibiotic, anti-fungi and antiviral activity.
Tissue specificity: Bone marrow."	"Gram-positive bacteria: Staphylococcus aureus, Streptococcus;##Gram-negative bacteria: Escherichia coli, Pseudomonas aeruginosa.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2473036##3623703	Infect Immun. 1989 Aug;57(8):2405-2409.##Infect Immun. 1987 Sep;55(9):2281-2286.	"Yamashita T, Saito K.##Selsted ME, Harwig SS."	"Purification, primary structure, and biological activity of guinea pig neutrophil cationic peptides.##Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin."
DRAMP02987	AGFAAQAAASLAPVAIQQL	19	Tricholongin BII (Fungi)	No entry found	Not found	Not found	Trichoderma longibrachiatum	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1935961	Eur J Biochem. 1991 Nov 1;201(3):661-674.	"Rebuffat S, Prigent Y, Auvin-Guette C, Bodo B."	"Tricholongins BI and BII, 19-residue peptaibols from Trichoderma longibrachiatum. Solution structure from two-dimensional NMR spectroscopy."
DRAMP02988	AGFAAQAAASLAPVAAQQL	19	Tricholongin BI (Fungi)	No entry found	Not found	Not found	Trichoderma longibrachiatum	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1935961	Eur J Biochem. 1991 Nov 1;201(3):661-674.	"Rebuffat S, Prigent Y, Auvin-Guette C, Bodo B."	"Tricholongins BI and BII, 19-residue peptaibols from Trichoderma longibrachiatum. Solution structure from two-dimensional NMR spectroscopy."
DRAMP02992	GLPRKILCAIAKKKGKCKGPLKLVCKC	27	"Lasiocepsin (Insects, animals)"	No entry found	Not found	Not found	Lasioglossum laticeps (Eusocial Bee)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Not found	Not found	None	"Function: The synthetic lasiocepsin possessed antimicrobial activity against both Gram-positive and -negative bacteria, antifungal activity against Candida albicans, and weak hemolytic activity against human erythrocytes."	No MICs found in DRAMP database	[Ref.22038181]LC50>200 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22038181	Amino Acids. 2012 Aug;43(2):751-761.	"Monincov¨¢ L, Slaninov¨¢ J, Fuc¨ªk V, Hovorka O, Voburka Z, Bedn¨¢rov¨¢ L, Malon P, Stokrov¨¢ J, Cerovsk? V."	"Lasiocepsin, a novel cyclic antimicrobial peptide from the venom of eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). "
DRAMP03006	VTCDLLSIKGVAEHSACAANCLSMGKAGGRCENGICLCRKTTFKELWDKRF	51	"Defensin (Insects, animals)"	P81462	Belongs to the invertebrate defensin family (Type 1 subfamily)	Not found	Bombus pascuorum (Brown bumblebee)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: Antibacterial peptide against Gram-positive and Gram-negative bacteria and fungi.
Induction: By bacterial infection."	Gram-negative bacteria: Micrococcus luteus;##Gram-negative bacteria: Escherichia coli D22.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9219367	Insect Biochem Mol Biol. 1997 May;27(5):413-422.	"Rees JA, Moniatte M, Bulet P."	"Novel antibacterial peptides isolated from a European bumblebee, Bombus pascuorum (Hymenoptera, Apoidea)."
DRAMP03013	LNLTKWLGKLGVILSHLNK	19	"Bombolitin-6 (Insects, animals)"	P0CD67	Belongs to the MCD family Bombolitin subfamily	Not found	Bombus lapidarius (Red-tailed bumblebee) (Apis lapidaria)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Mast cell degranulating peptide. May also display antibacterial and antifungal activities (By similarity).
Tissue specificity: Expressed by the venom gland."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16626777	Toxicon. 2006 May;47(6):676-687.	"Favreau P, Menin L, Michalet S, Perret F, Cheneval O, St?cklin M, Bulet P, St?cklin R."	Mass spectrometry strategies for venom mapping and peptide sequencing from crude venoms: case applications with single arthropod specimen.
DRAMP03014	LKLKDILGKIKVILSHLNK	19	"Bombolitin-7 (Insects, animals)"	P0CD68	Belongs to the MCD family Bombolitin subfamily	Not found	Bombus lapidarius (Red-tailed bumblebee) (Apis lapidaria)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Mast cell degranulating peptide. May also display antibacterial and antifungal activities (By similarity).
Tissue specificity: Expressed by the venom gland."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16626777	Toxicon. 2006 May;47(6):676-687.	"Favreau P, Menin L, Michalet S, Perret F, Cheneval O, St?cklin M, Bulet P, St?cklin R."	Mass spectrometry strategies for venom mapping and peptide sequencing from crude venoms: case applications with single arthropod specimen.
DRAMP03015	LKLKSILGKLGVILSHLNK	19	"Bombolitin-8 (Insects, animals)"	P0CD69	Belongs to the MCD family Bombolitin subfamily	Not found	Bombus lapidarius (Red-tailed bumblebee) (Apis lapidaria)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Mast cell degranulating peptide. May also display antibacterial and antifungal activities (By similarity).
Tissue specificity: Expressed by the venom gland."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16626777	Toxicon. 2006 May;47(6):676-687.	"Favreau P, Menin L, Michalet S, Perret F, Cheneval O, St?cklin M, Bulet P, St?cklin R."	Mass spectrometry strategies for venom mapping and peptide sequencing from crude venoms: case applications with single arthropod specimen.
DRAMP18418	FIGMIPGLIGGLISAFK	17	ToAP1	A0A1D3IXR7	Derived from NDBP subfamily 4	Not found	Tityus obscurus	"Antimicrobial, Antifungal, Antibiofilm"	Transcript level	Alpha helix	The peptide adopts a structure with 64.71% alpha helix	None	Function: Antibacterial activity against the all Candida spp. Has hemolytic activity.	"[Ref.27917162] Fungi:Candida albicans (SC5314)(MIC=50¦ÌM), Candida tropicalis (ATCC 750)(MIC=12.5¦ÌM), Candida parapsilosis (ATCC 22019)(MIC=200¦ÌM), Candida glabrata (ATCC 90030)(MIC>400¦ÌM), Candida neoformans (H99 serotype A)(MIC=25¦ÌM)"	"[Ref.27917162] 20% hemolysis at 1.58 ¦ÌM, 22% hemolysis at 3.16 ¦ÌM, 23% hemolysis at 6.31 ¦ÌM, 24% hemolysis at 12.59 ¦ÌM, 28% hemolysis at 25.12 ¦ÌM, 45% hemolysis at 50.11 ¦ÌM , 50% hemolysis at 100¦ÌM against human red blood cell"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27917162	Front Microbiol. 2016 Nov 18;7:1844. eCollection 2016.	"Guilhelmelli F, Vilela N, Smidt KS, de Oliveira MA, da Cunha Morales ?lvares A, Rigonatto MC, da Silva Costa PH, Tavares AH, de Freitas SM, Nicola AM, Franco OL, Derengowski LD, Schwartz EF, Mortari MR, Bocca AL, Albuquerque P, Silva-Pereira I."	Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms.
DRAMP03023	INWKALLDAAKKVL	14	"Mastoparan (Protonectarina-MP; Insects, animals)"	P0C1Q5	Not found	Not found	Protonectarina sylveirae (Brazilian wasp)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Not found	Not found	None	"Function: Shows potent antimicrobial action against both Gram-positive and Gram-negative bacteria By similarity. This peptide shows potent histamine releasing activities on rat peritoneal mast cells. Also Has hemolytic and cytolytic activity.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation (Leucine amide: L14)."	[Swiss_Prot Entry P0C1Q5]Potent antimicrobial peptide against both Gram-positive and Gram-negative bacteria (By similarity)	[Ref.20108158]ED50 =3.4 ¡Á 10?5 M against rat red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7513243##19857508##20108158	Nat Toxins. 1993;1(5):271-276.##Toxicon. 2010 Apr 1;55(4):711-718.##Amino Acids. 2011 Jan;40(1):77-90.	"Dohtsu K, Okumura K, Hagiwara K, Palma MS, Nakajima T.##Baek JH, Lee SH.##de Souza BM, Dos Santos Cabrera MP, Neto JR, Palma MS."	Isolation and sequence analysis of peptides from the venom of Protonectarina sylveirae (Hymenoptera-Vespidae).##Isolation and molecular cloning of venom peptides from Orancistrocerus drewseni (Hymenoptera: Eumenidae).##Investigating the effect of different positioning of lysine residues along the peptide chain of mastoparans for their secondary structures and biological activities.
DRAMP18227	LLDVLLE	7	Gageostatin B (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	"Leu-Leu-Asp-Val-Leu-Leu-Glu-3-beta-hydroxy-9, 11-dimethyltridecanoic acid"	None	"surfactin like heptapeptides, cytotoxic. It is noteworthy that these compounds 1"	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	24492520	Mar Drugs. 2014 Jan 31;12(2):871-85. 	"Tareq FS, Lee MA, Lee HS, Lee JS, Lee YJ, Shin HJ."	"Gageostatins A-C, antimicrobial linear lipopeptides from a marine Bacillus subtilis."
DRAMP03048	KDLHTVVSAILQAL	14	"Venom peptide 3 (OdVP3; Insects, animals)"	C7DT09	Belongs to the MCD family	VP3	Orancistrocerus drewseni (Solitary wasp)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Exhibits strong antimicrobial activity. 
Tissue specificity: Expressed by the venom gland."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19857508	Toxicon. 2010 Apr 1;55(4):711-718.	"Baek JH, Lee SH."	Isolation and molecular cloning of venom peptides from Orancistrocerus drewseni (Hymenoptera: Eumenidae).
DRAMP03049	GRILSFIKGLAEHL	14	"Eumenine mastoparan-OD (EMP-OD; Venom peptide 1, OdVP1; Insects, animals)"	"P86146, C7DT07"	Belongs to the MCD family (Mastoparan subfamily)	VP1	Orancistrocerus drewseni (Solitary wasp)	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Protein level	Not found	Not found	None	"Function: Has hemolytic activity against ovine erythrocytes at micromolar concentrations. Also exhibits strong antimicrobial activity.
Tissue specificity: Expressed by the venom gland.
PTM: C-terminal amidation (Leucine amide: L14)."	"[Ref.19857508]Fungi: Candida albicans, Botrytis cinerea (++);##Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: S. aureus (+)"	[Ref.18695936]42% hemolytic activity at 50 ¦ÌM against sheep blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane (Note: Assumes an amphipathic alpha-helical conformation in a lipid environmen	19857508##18695936	Toxicon. 2010 Apr 1;55(4):711-718.##Amino Acids. 2009 Jul;37(2):389-394.	"Baek JH, Lee SH.##Murata K, Shinada T, Ohfune Y, Hisada M, Yasuda A, Naoki H, Nakajima T."	"Isolation and molecular cloning of venom peptides from Orancistrocerus drewseni (Hymenoptera: Eumenidae).##Novel mastoparan and protonectin analogs isolated from a solitary wasp, Orancistrocerus drewseni drewseni."
DRAMP03065	GVSGHGQHGVHG	12	"Alloferon-2 (Insects, animals)"	No entry found	Not found	Not found	Calliphora vicina (Blue blowfly) (Calliphora erythrocephala)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Not found	Not found	None	"Function: Alloferon can (i) stimulate natural cytotoxicity of human peripheral blood lymphocytes, (ii) induces IFN synthesis in mouse and human models, and (iii) enhances antiviral and antitumor resistance in mice. "	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12235362	Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12628-32.	"Chernysh S, Kim SI, Bekker G, Pleskach VA, Filatova NA, Anikin VB, Platonov VG, Bulet P."	Antiviral and antitumor peptides from insects.
DRAMP18226	LLDVLLE	7	Gageostatin A (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus subtilis	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	Leu-Leu-Asp-Val-Leu-Leu-Glu-3-beta-hydroxy-11-methyltridecanoic acid	None	"Fuction: Surfactin like heptapeptides, cytotoxic. It is noteworthy that these compounds 1"	"Gram-positive, Gram-negative"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	24492520	Mar Drugs. 2014 Jan 31;12(2):871-85. 	"Tareq FS, Lee MA, Lee HS, Lee JS, Lee YJ, Shin HJ."	"Gageostatins A-C, antimicrobial linear lipopeptides from a marine Bacillus subtilis."
DRAMP03077	GWLKKIGKKIERVGQHTRDATIQTIGVAQQAANVAATLK	39	"Cecropin-2 (Cecropin 2; Md-Cec, Mdc; Insects, animals)"	Q06590	Belongs to the cecropin family	CEC2	Ceratitis capitata (Mediterranean fruit fly) (Musca domestica)	"Antimicrobial, Antibacterial, Antifungal"	Homology	Alpha helix 	Not found	None	"Function: Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
PTM: C-terminal amidation (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7916722	Gene. 1993 Dec 8;134(2):241-243.	"Rosetto M, Manetti AG, Marchini D, Dallai R, Telford JL, Baldari CT."	Sequences of two cDNA clones from the medfly Ceratitis capitata encoding antibacterial peptides of the cecropin family.
DRAMP03087	DDMTMKPTPPPQYPLNLQGGGGGGSGDGFGFAVQGHQKVWTSDNGRHEIGLNGGYGQHLGGPYGNSEPSWKVGSTYTYRFPNF	83	"Drosophila diptericin (Insects, animals)"	No entry found	Not found	Not found	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	2125051	J Biol Chem. 1990 Dec 25;265(36):22493-8.	"Wicker C, Reichhart JM, Hoffmann D, Hultmark D, Samakovlis C, Hoffmann JA."	Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides.
DRAMP03093	DCLSGRYKGPCAVWDNETCRRVCKEEGRSSGHCSPSLKCWCEGC	44	"Drosomycin (Cys-rich; insect defensins; Insects, animals)"	"P41964, Q2UYN5, Q9VZQ2"	Not found	Drs	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antifungal"	Protein level	Combine helix and strand structure	Not found	1MYN resolved by NMR.	"Function: Possesses antifungal activity and is active against a relatively broad spectrum of filamentous fungi. It inhibits spore germination at high concentrations and at low concentrations delays growth of hyphae which subsequently exhibit abnormal morphology. Spz C-106 in the hemolymph controls expression of the antifungal peptide by acting as a ligand of Tl and inducing an intracellular signaling pathway.
Tissue specificity: Synthesized in the fat body and is secreted into the blood. In hemolymph 6 hours after immune challenge, levels of expression increase for first 24 hours and persist for the following three weeks.
PTM: Contains four disulfide bonds 2-44; 11-33; 19-39; 23-41."	"Fungi: Neurospora crassa (IC50=0.6 ?M), Botrytis cinerea (IC50=1.2 ?M), Fusarium culmorum (IC50=1.0 ?M), Alternaria brassicicola (IC50=0.9 ?M), A. longipes (IC50=1.4 ?M), Nectria haematococca (IC50=1.8 ?M), Fusarium oxysporum(IC50=4.2 ?M), A. pisi (IC50=3.2 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization (Cys2 and Cys44)	"Disulfide bonds between Cys2 and Cys44; Cys11 and Cys33; Cys19 and Cys39,Cys23 and Cys41."	L	No cytotoxicity information found	Not found	7806546##8808632##9736738##12872120	J Biol Chem 1994; 269: 33159-33163.##Cell. 1996 Sep 20;86(6):973-983.##Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11342-11347.##Nat Immunol. 2003 Aug;4(8):794-800.	"Fehlbaum P et al Hoffmann JA.##Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA.##Uttenweiler-Joseph S, Moniatte M, Lagueux M, Van Dorsselaer A, Hoffmann JA, Bulet P.##Weber AN, Tauszig-Delamasure S, Hoffmann JA, Leli¨¨vre E, Gascan H, Ray KP, Morse MA, Imler JL, Gay NJ."	Insect immunity. Septic injury of drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides.##The dorsoventral regulatory gene cassette sp?tzle/Toll/cactus controls the potent antifungal response in Drosophila adults.##Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study.##Binding of the Drosophila cytokine Sp?tzle to Toll is
DRAMP03094	DCLSGKYKGPCAVWDNEMCRRICKEEGHISGHCSPSLKCWCEGC	44	"Drosomycin-2 (Insects, animals)"	No entry found	Not found	Not found	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antifungal, Antiparasitic"	Not found	Not found	Not found	None	"Function: Drosomycin-2 is antiparasitic peptide which shows inhibitory effect on the ookinete development of the parasite Plasmodium berghei.
Induction: Expressed in larva, pupa and adult."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18657321	Mol Immunol. 2008 Sep;45(15):3909-3916.	"Tian C, Gao B, Rodriguez Mdel C, Lanz-Mendoza H, Ma B, Zhu S."	"Gene expression, antiparasitic activity, and functional evolution of the drosomycin family."
DRAMP03099	QRPYTQPLIYYPPPPTPPRIYRA	23	"Attacin-C (Insects, animals)"	Q95NH6	Not found	AttC	Drosophila melanogaster (Fruit fly)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Rich	Not found	None	Comment: No comments found on DRAMP database	"Agrobacterium tumefaciens (MIC>200 ?M), Enterobacter cloacae b12 (MIC>200 ?M), Escherichia coli SBS 363 (MIC>200 ?M), Escherichia coli D31 (MIC>=200 ?M), Escherichia coli D22 (MIC>=200 ?M), Erwinia carotovora carotovora (MIC>200 ?M), Pseudomonas aeruginosa (MIC>200 ?M), Salmonella typhimurium (MIC>200 ?M), Serratia marcescens (MIC>200 ?M), Bacillus megaterium (MIC>200 ?M), Micrococcus luteus(MIC>200 ?M), Staphylococcus aureus (MIC>200 ?M), Streptococcus pyogenes (MIC>200 ?M), Neurospora crassa (MIC>200 ?M), Aspergillus fumigatus (MIC>200 ?M), Candida albicans (MIC>200 ?M), Candida glabrata (MIC>200 ?M), Cryptococcus neoformans (MIC>200 ?M), Saccharomyces cerevisiae (MIC>200 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14744858	J Biol Chem. 2004 Apr 9;279(15):14853-9. Epub 2004 Jan 26.	"Rabel D, Charlet M, Ehret-Sabatier L, Cavicchioli L, Cudic M, Otvos L Jr, Bulet P."	Primary structure and in vitro antibacterial properties of the Drosophila melanogaster attacin C Pro-domain.
DRAMP03105	QHGHGGQDQHGYGHGQQAVYGKGHEGHGVNNLGQDGHGQHGYAHGHSDQHGHGGQHGQHDGYKNRGY	67	"Antifungal protein (AFP; Insects, animals)"	Q08617	Not found	Not found	Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: This protein inhibits the growth of a variety of fungal species. The antifungal activity of this protein is enhanced by the presence of sarcotoxin IA.	Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8505329##8454635	J Biol Chem. 1993 Jun 5;268(16):12055-12061.##J Biol Chem. 1993 Mar 25;268(9):6641-6648.	"Iijima R, Kurata S, Natori S.##Selsted ME, Tang YQ, Morris WL, McGuire PA, Novotny MJ, Smith W, Henschen AH, Cullor JS."	"Purification, characterization, and cDNA cloning of an antifungal protein from the hemolymph of Sarcophaga peregrina (flesh fly) larvae.##Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils."
DRAMP03174	RWCVYAYVRIRGVLVRYRRCW	21	"Arenicin-2 (Ar-2; marine polychaeta, animals)"	"Q5SC59, P84106"	Not found	Not found	Arenicola marina (Lugworm) (Lumbricus marinus)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Beta strand (2 strands; 16 residues)	"NMR investigation shows that in water solution arenicin-2 displays a prolonged beta-hairpin, formed by two antiparallel beta-strands and stabilized by one disulfide and nine hydrogen bonds. A significant right-handed twist in the beta-sheet is deprived the peptide surface of amphipathicity. CD spectroscopic analysis indicates that arenicin-2 binds to the SDS and DPC micelles, and conformation of the peptide is significantly changed upon"	"2JNI, 2L8X resolved by NMR."	"Function: Has antimicrobial activity against the Gram-negative bacteria, Gram-positive bacteriua as well as yeast C. albicans. Bacterial killing occurs within minutes and is accompanied by membrane permeabilization, membrane detachment and release of cytoplasm. Interaction of arenicin with reconstituted membranes that mimic the lipopolysaccharide-containing outer membrane or the phospholipid-containing plasma membrane of Gram-negative bacteria exhibited no pronounced lipid specificity.
PTM: Contains one disulfide bond 3-20.
Domian: Contains 1 BRICHOS domain."	Gram-positive bacterium: Listeria monocytogenes EGD;##Gram-negative bacterium: Escherichia coli ML-35p.##Yeast: Candida albicans 820.	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bond between Cys3 and Cys20.	L	No cytotoxicity information found	Anionic lipid vesicles	15527787##17935487##17585874	FEBS Lett. 2004 Nov 5;577(1-2):209-214.##Biochem J. 2008 Feb 15;410(1):113-122.##Biochem Biophys Res Commun. 2007 Aug 17;360(1):156-162.	"Ovchinnikova TV, Aleshina GM, Balandin SV, Krasnosdembskaya AD, Markelov ML, Frolova EI, Leonova YF, Tagaev AA, Krasnodembsky EG, Kokryakov VN.##Andr? J, Jakovkin I, Gr?tzinger J, Hecht O, Krasnosdembskaya AD, Goldmann T, Gutsmann T, Leippe M.##Ovchinnikova TV, Shenkarev ZO, Nadezhdin KD, Balandin SV, Zhmak MN, Kudelina IA, Finkina EI, Kokryakov VN, Arseniev AS."	"Purification and primary structure of two isoforms of arenicin, a novel antimicrobial peptide from marine polychaeta Arenicola marina.##Structure and mode of action of the antimicrobial peptide arenicin.##Recombinant expression, synthesis, purification, and solution structure of arenicin."
DRAMP03175	FNKLKQGSSKRTCAKCFRKIMPSVHELDERRRGANRWAAGFRKCVSSICRY	51	Perinerin	"P84117, P83551"	Not found	Not found	Nereis aibuhitensis (Clamworm) (Perinereis aibuhitensis)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Antibacterial activity against both Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas aeruginosa, Escherichia coli K-12, Proteus vulgaris;##Gram-positive bacteria: Bacillus megaterium, Aerococcus viridans, Staphylococcus aureus, Micrococcus luteus."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15113828	J Biochem. 2004 Mar;135(3):297-304.	"Pan W, Liu X, Ge F, Han J, Zheng T."	"Perinerin, a novel antimicrobial peptide purified from the clamworm Perinereis aibuhitensis grube and its partial characterization."
DRAMP03177	SWLSKTYKKLENSAKKRISEGIAIAIQGGPR	31	"Cecropin-P2 (CP2; nematodes, animals)"	Q5H7N6	Belongs to the cecropin family	ASCEC-2	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antibacterial activity against several Gram-positive and Gram-negative bacteria. Is weakly active against yeasts. Acts by a nonpore mechanism.
Induction: By bacterial infection."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15850460	Biochem J. 2005 Aug 15;390(Pt 1):207-214.	"Pillai A, Ueno S, Zhang H, Lee JM, Kato Y."	Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum.
DRAMP03178	SWLSKTAKKLENSAKKRISEGIAIAIKGGSR	31	"Cecropin-P3 (CP3; nematodes, animals)"	Q5H7N5	Belongs to the cecropin family	ASCEC-3	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antibacterial activity against several Gram-positive and Gram-negative bacteria. Is weakly active against yeasts. Acts by a nonpore mechanism.
Induction: By bacterial infection."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15850460	Biochem J. 2005 Aug 15;390(Pt 1):207-214.	"Pillai A, Ueno S, Zhang H, Lee JM, Kato Y."	Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum.
DRAMP03179	SWLSKTYKKLENSAKKRISEGVAIAILGGLR	31	"Cecropin-P4 (CP4; nematodes, animals)"	Q5H7N4	Belongs to the cecropin family	ASCEC-4	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antibacterial activity against several Gram-positive and Gram-negative bacteria. Is weakly active against yeasts. Acts by a nonpore mechanism.
Tissue specificity: Expressed in the body wall, intestine, uterus and ovary.
Induction: Induced as part of the humoral response to a bacterial invasion. Transcripts appear within the immunized fat body."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15850460	Biochem J. 2005 Aug 15;390(Pt 1):207-214.	"Pillai A, Ueno S, Zhang H, Lee JM, Kato Y."	Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum.
DRAMP03180	AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGRGGGEWPSVPMPKGRSSRGRRHS	75	"ASABF-alpha (ASABF; nematodes, animals)"	P90683	Not found	asabf-alpha	Ascaris suum (Pig roundworm) (Ascaris lumbricoides)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Combine helix and strand structure	Not found	2D56 resolved by NMR.	Slight hemolytic activity against human erythrocytes. 	"[Ref.10991847]Gram-negative bacteria: Escherichia coli JM109 (IC50=50 ?g/ml), Proteus vulgaris ATCC 13315 (IC50=10 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC6538P (IC50=0.6 ?g/ml), Bacillus subtilis ATCC6633 (IC50=1.2 ?g/ml), Micrococcus luteus ATCC398 (IC50=0.8 ?g/ml)."	[Ref.10991847]4.5% hemolytic activity at 1000 ¦Ìg/ml against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8940016##10991847	J Biol Chem. 1996 Nov 29;271(48):30493-30498.##Antimicrob Agents Chemother. 2000 Oct;44(10):2701-2715.	"Kato Y, Komatsu S.##Zhang H, Yoshida S, Aizawa T, Murakami R, Suzuki M, Koganezawa N, Matsuura A, Miyazawa M, Kawano K, Nitta K, Kato Y."	"ASABF, a novel cysteine-rich antibacterial peptide isolated from the nematode Ascaris suum. Purification, primary structure, and molecular cloning of cDNA.##In vitro antimicrobial properties of recombinant ASABF, an antimicrobial peptide isolated from the nematode Ascaris suum."
DRAMP03182	ACNFQSCWATCQAQHSIYFRRAFCDRSQCKCVFVRG	36	"Termicin (Termite defensin; Insects, animals)"	P82321	Not found	Not found	Pseudacanthotermes spiniger 	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Combine helix and strand structure	Not found	1MM0 resolved by NMR.	Function: Has antibacterial activity.	"Gram-positive bacteria: Bacillus megaterium, Micrococcus luteus, Streptococcus pyogenes(++).##Fungi: Fusarium culmorum, Fusarium oxysporum, Neurospora crassa, Nectria haematococca, Trichoderma viride(+); Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisiae(+++)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11053427##12592014	J Biol Chem. 2001 Feb 9;276(6):4085-4092.##Protein Sci. 2003 Mar;12(3):438-446.	"Lamberty M, Zachary D, Lanot R, Bordereau C, Robert A, Hoffmann JA, Bulet P.##Da Silva P, Jouvensal L, Lamberty M, Bulet P, Caille A, Vovelle F."	"Insect immunity. Constitutive expression of a cysteine-rich antifungal and a linear antibacterial peptide in a termite insect.##Solution structure of termicin, an antimicrobial peptide from the termite Pseudacanthotermes spiniger."
DRAMP03185	SFGLCRLRRGFCAHGRCRFPSIPIGRCSRFVQCCRRVW	38	"Spheniscin-1 (Sphe-1; penguin avian beta-defensin 103a; birds ,animals)"	P83429	Belongs to the beta-defensin family	Not found	Aptenodytes patagonicus (King penguin)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity and antibacterial activity against Gram-positive and Gram-negative bacteria. Involved in the process of food preservation in the stomach during the incubation fast. May also be present during infection.
PTM: Contains three disulfide bond: 5-33; 12-27; 17-34.
Tissue specificity: Secreted into the stomach cavity."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bonds between Cys5 and Cys33; Cys12 and Cys27; Cys17 and Cys34.	L	No cytotoxicity information found	Not found	14525994	J Biol Chem. 2003 Dec 19;278(51):51053-8. 	"Thouzeau C, Le Maho Y, Froget G, Sabatier L, Le Bohec C, Hoffmann JA, Bulet P."	"Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus."
DRAMP18221	TVYTQA	6	Fusaricidin D (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus polymyxa KT-8	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"		Not found	"The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Gln5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). "	None	"Fusaricidin A was elucidated to be a cyclic depsipeptide containing a unique fatty acid, 15-guanidino-3-hydroxypentadecanoic acid. Fusaricidins B, C, and D are minor components from the culture broth of a bacterial strain Bacillus polymyxa KT-8."	Gram-positive	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9127193##23185515	J Antibiot (Tokyo). 1997 Mar;50(3):220-8.##PLoS One. 2012;7(11):e50003.	"Kajimura Y, Kaneda M.##Yu WB, Yin CY, Zhou Y, Ye BC."	"Fusaricidins B, C and D, new depsipeptide antibiotics produced by Bacillus polymyxa KT-8: isolation, structure elucidation and biological activity.##Prediction of the mechanism of action of fusaricidin on Bacillus subtilis."
DRAMP03194	RCVCTRGFC	9	"Theta defensin subunit A (primates, mammals, animals)"	P86722	Belongs to the alpha-defensin family (Theta subfamily)	Not found	Papio hamadryas (Hamadryas baboon)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Forms a cyclic peptide with subunit A (PhTD-3) or with subunit B (PhTD-1). An additional intersubunit disulfide bond is formed. 	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20155756	Rapid Commun Mass Spectrom. 2010 Mar 15;24(5):599-604.	"Stegemann C, Tsvetkova EV, Aleshina GM, Lehrer RI, Kokryakov VN, Hoffmann R."	De novo sequencing of two new cyclic theta-defensins from baboon (Papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry.
DRAMP03195	RCVCRRGVC	9	"Theta defensin subunit B (primates, mammals, animals)"	P86723	Belongs to the alpha-defensin family (Theta subfamily)	Not found	Papio hamadryas (Hamadryas baboon)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Forms a cyclic peptide with subunit A (PhTD-1). An additional intersubunit disulfide bond is formed. 	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20155756	Rapid Commun Mass Spectrom. 2010 Mar 15;24(5):599-604.	"Stegemann C, Tsvetkova EV, Aleshina GM, Lehrer RI, Kokryakov VN, Hoffmann R."	De novo sequencing of two new cyclic theta-defensins from baboon (Papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry.
DRAMP03199	RRICRCRIGRCLGLEVYFGVCFLHGRLARRCCR	33	"PhD1 (PhD-1; Defensin-1; primates, mammals, animals)"	P84757	Not found	Not found	Papio hamadryas (Hamadryas baboon)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli;##Gram-positive bacteria: Listeria monocytogenes, Staphylococcus aureus.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16978151	Biochemistry (Mosc). 2006 Aug;71(8):879-883.	"Tsvetkova EV, Aleshina GM, Shamova OV, Leonova LE, Lehrer RI, Kokryakov VN."	alpha-Defensins from blood leukocytes of the monkey Papio hamadryas.
DRAMP03200	RICRCRIGRCLGLEVYFGVCFLHGRLARRCCR	32	"PhD2 (PhD-2; Defensin-2; primates, mammals, animals)"	P84757	Belongs to the alpha-defensin family	Not found	Papio hamadryas (Hamadryas baboon)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli;##Gram-positive bacteria: Listeria monocytogenes, Staphylococcus aureus.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16978151	Biochemistry (Mosc). 2006 Aug;71(8):879-83.	"Tsvetkova EV, Aleshina GM, Shamova OV, Leonova LE, Lehrer RI, Kokryakov VN."	alpha-Defensins from blood leukocytes of the monkey Papio hamadryas.
DRAMP03201	RTCRCRLGRCSRRESYSGSCNINGRIYSLCCR	32	"PhD3 (PhD-3; Defensin-3; primates, mammals, animals)"	P84758	Belongs to the alpha-defensin family	Not found	Papio hamadryas (Hamadryas baboon)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	Comment: No comments found on DRAMP database	"Gram-negative bacterium: Escherichia coli;##Gram-positive bacteria: Listeria monocytogenes, Staphylococcus aureus.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16978151	Biochemistry (Mosc). 2006 Aug;71(8):879-883.	"Tsvetkova EV, Aleshina GM, Shamova OV, Leonova LE, Lehrer RI, Kokryakov VN."	alpha-Defensins from blood leukocytes of the monkey Papio hamadryas.
DRAMP18220	TVYTNA	6	Fusaricidin C (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus polymyxa KT-8	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"		Not found	"The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Asn5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). "	None	"Fusaricidin A was elucidated to be a cyclic depsipeptide containing a unique fatty acid, 15-guanidino-3-hydroxypentadecanoic acid. Fusaricidins B, C, and D are minor components from the culture broth of a bacterial strain Bacillus polymyxa KT-8."	Gram-positive	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9127193##23185515	J Antibiot (Tokyo). 1997 Mar;50(3):220-8.##PLoS One. 2012;7(11):e50003.	"Kajimura Y, Kaneda M.##Yu WB, Yin CY, Zhou Y, Ye BC."	"Fusaricidins B, C and D, new depsipeptide antibiotics produced by Bacillus polymyxa KT-8: isolation, structure elucidation and biological activity.##Prediction of the mechanism of action of fusaricidin on Bacillus subtilis."
DRAMP18219	TVVTQA	6	Fusaricidin B (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus polymyxa KT-8	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"		Not found	"The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Gln5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). "	None	"Fusaricidin A was elucidated to be a cyclic depsipeptide containing a unique fatty acid, 15-guanidino-3-hydroxypentadecanoic acid. Fusaricidins B, C, and D are minor components from the culture broth of a bacterial strain Bacillus polymyxa KT-8."	Gram-positive	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9127193##23185515	J Antibiot (Tokyo). 1997 Mar;50(3):220-8.##PLoS One. 2012;7(11):e50003.	"Kajimura Y, Kaneda M.##Yu WB, Yin CY, Zhou Y, Ye BC."	"Fusaricidins B, C and D, new depsipeptide antibiotics produced by Bacillus polymyxa KT-8: isolation, structure elucidation and biological activity.##Prediction of the mechanism of action of fusaricidin on Bacillus subtilis."
DRAMP03206	RCICLLGIC	9	"Theta defensin subunit C (BTD-c; BTD-4 subunit 2; primates, mammals, animals)"	"B6ULW6, P86033"	Belongs to the alpha-defensin family (Theta subfamily)	BTDC	Papio anubis (Olive baboon)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Forms a cyclic peptide with subunit A (BTD-4). An additional intersubunit disulfide bond is formed. 	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18852242	Infect Immun. 2008 Dec;76(12):5883-5891.	"Garcia AE, Osapay G, Tran PA, Yuan J, Selsted ME."	"Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes."
DRAMP03207	RCFCRRGVC	9	"Theta defensin subunit D (BTD-d; BTD-7 subunit 2; primates, mammals, animals)"	"B6ULW7, P86034"	Belongs to the alpha-defensin family (Theta subfamily)	BTDD	Papio anubis (Olive baboon)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Forms a cyclic peptide with subunit A (BTD-7). An additional intersubunit disulfide bond is formed.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18852242	Infect Immun. 2008 Dec;76(12):5883-5891.	"Garcia AE, Osapay G, Tran PA, Yuan J, Selsted ME."	"Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes."
DRAMP03208	RCVCTRGFCRCVCRRGVC	18	"BTD-1 (theta-defensin; primates, mammals, animals)"	"B6ULW4, P86031, B6ULW5, P86032"	Not found	Not found	Papio anubis (Olive baboon)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: BTD-1 has antimicrobial activity against the Gram-negative bacterium E. coli ML35 and the Gram-positive bacterium S. aureus 502a, and the fungus C. albicans 16820. "	Gram-positive bacterium: Staphylococcus aureus 502a;##Gram-negative bacterium: Escherichia coli ML35.##Fungi: Candida albicans 16820.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	18852242	Infect Immun. 2008 Dec;76(12):5883-5891.	"Garcia AE, Osapay G, Tran PA, Yuan J, Selsted ME."	"Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes."
DRAMP03209	RCVCRRGVCRCVCRRGVC	18	"BTD-2 (theta-defensin; primates, mammals, animals)"	"B6ULW5, P86032"	Not found	Not found	Papio anubis (Olive baboon)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: BTD-2 has antimicrobial activity against the Gram-negative bacterium E. coli ML35 and the Gram-positive bacterium S. aureus 502a, and the fungus C. albicans 16820. Among the five BTDs detected, the most potent peptide is BTD-2. BTD-2 is more effective against E. coli than BTD-1."	Gram-positive bacterium: Staphylococcus aureus 502a;##Gram-negative bacterium: Escherichia coli ML35.##Fungi: Candida albicans 16820.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	18852242	Infect Immun. 2008 Dec;76(12):5883-5891.	"Garcia AE, Osapay G, Tran PA, Yuan J, Selsted ME."	"Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes."
DRAMP18218	TVVTNA	6	Fusaricidin A (Bacteriocin)	No entry found	Belongs to the lipopeptides family	Not found	Bacillus polymyxa KT-8	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"		Not found	"The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Asn5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). "	None	"Fusaricidin A was elucidated to be a cyclic depsipeptide containing a unique fatty acid, 15-guanidino-3-hydroxypentadecanoic acid. Fusaricidins B, C, and D are minor components from the culture broth of a bacterial strain Bacillus polymyxa KT-8."	Gram-positive	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8621351##23185515 	J Antibiot (Tokyo). 1996 Feb;49(2):129-35.##PLoS One. 2012;7(11):e50003.	"Kajimura Y, Kaneda M.##Yu WB, Yin CY, Zhou Y, Ye BC."	"Fusaricidin A, a new depsipeptide antibiotic produced by Bacillus polymyxa KT-8. Taxonomy, fermentation, isolation, structure elucidation and biological activity.##Prediction of the mechanism of action of fusaricidin on Bacillus subtilis."
DRAMP03211	RCVCTRGFCRCICLLGIC	18	"BTD-4 (theta-defensin; primates, mammals, animals)"	"B6ULW4, B6ULW6"	Not found	Not found	Papio anubis (Olive baboon)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: BTD-4 has antimicrobial activity against the Gram-negative bacterium E. coli ML35 and the Gram-positive bacterium S. aureus 502a, and the fungus C. albicans 16820. Among the five BTD detected, BTD-4 is least positively charged (net charge +2). This may be responsible for its weaker antimicrobial activity observed in vitro. It disrupts E. coli membranes."	Gram-positive bacterium: Staphylococcus aureus 502a;##Gram-negative bacterium: Escherichia coli ML35.##Fungi: Candida albicans 16820.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	18852242	Infect Immun. 2008 Dec;76(12):5883-5891.	"Garcia AE, Osapay G, Tran PA, Yuan J, Selsted ME."	"Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes."
DRAMP03212	RCVCTRGFCRCFCRRGVC	18	"BTD-7 (theta-defensin; primates, mammals, animals)"	"B6ULW4, B6ULW7"	Not found	Not found	Papio anubis (Olive baboon)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: BTD-7 has antimicrobial activity against the Gram-negative bacterium E. coli ML35 and the Gram-positive bacterium S. aureus 502a, and the fungus C. albicans 16820. "	Gram-positive bacterium: Staphylococcus aureus 502a;##Gram-negative bacterium: Escherichia coli ML35.##Fungi: Candida albicans 16820.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	18852242	Infect Immun. 2008 Dec;76(12):5883-5891.	"Garcia AE, Osapay G, Tran PA, Yuan J, Selsted ME."	"Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes."
DRAMP03228	GLFGKLIKKFGRKAISYAVKKARGKN	26	"M-zodatoxin-Lt2b (M-ZDTX-Lt2b; Latarcin-2b, Ltc-2b; spiders, Arthropods, animals)"	Q1ELU0	Belongs to the latarcin family	Not found	Lachesana tarabaevi (Spider)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antimicrobial activity against both Gram-positive and Gram-negative bacteria, and the yeasts. Also has a strong hemolytic activity against rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae.
Tissue specificity: Expressed by the venom gland."	No MICs found in DRAMP database	[Swiss_Prot Entry Q1ELU0]has a strong hemolytic activity against rabbit erythrocytes 	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16735513	J Biol Chem. 2006 Jul 28;281(30):20983-209892.	"Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV."	"Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity."
DRAMP03235	QAFKTFTPDWNKIRNDAKRMQDNLEQMKKRFNLNL	35	"M-zodatoxin-Lt6b (M-ZDTX-Lt6b; Latarcin 6b, Ltc-6b; spiders, Arthropods, animals)"	Q1ELU8	Belongs to the latarcin family	Not found	Lachesana tarabaevi (Spider)	"Antibacterial, Antimicrobial, Antifungal, Antiviral"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16735513	J Biol Chem. 2006 Jul 28;281(30):20983-20992. 	"Kozlov SA, Vassilevski AA, Feofanov AV, Surovoy AY, Karpunin DV, Grishin EV. "	"Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity."
DRAMP03252	KIKWFKTMKSLAKFLAKEQMKKHLGE	26	"M-lycotoxin-Ls2a (M-LCTX-Ls2a; Lycocitin-3; spiders, Arthropods, animals)"	P0C2U8	Not found	Not found	Lycosa singoriensis (Wolf spider) (Aranea singoriensis)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Forms pore that permeabilize the cell membrane. Promotes efflux of calcium from synaptosomes, causes hemolysis, and dissipates voltage gradients across muscle membrane. Potently inhibits the growth of bacteria and yeast. May Function: both in the prey capture strategy as well as protection from infectious organisms arising from prey ingestion."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	14991689	J Mass Spectrom. 2004 Feb;39(2):193-201.	"Budnik BA, Olsen JV, Egorov TA, Anisimova VE, Galkina TG, Musolyamov AK, Grishin EV, Zubarev RA."	De novo sequencing of antimicrobial peptides isolated from the venom glands of the wolf spider Lycosa singoriensis.
DRAMP03258	IIIQYEGHKH	10	"Rondonin (spiders, Arthropods, animals)"	B3EWP8	Not found	Not found	Acanthoscurria rondoniae (Spider)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Exhibits antifungal activity against Candida sp. No hemolytic activity	No MICs found in DRAMP database	[Swiss_Prot Entry B3EWP8]Non-hemolytic activity	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Results Immunol. 2012;2:66-71.	"Riciluca K.C.T, Sayegh R.S.R, Melo R.L, Silva P.I. Jr."	Rondonin an antifungal peptide from spider (Acanthoscurria rondoniae) haemolymph.
DRAMP18213	VKLFPVKLFP	10	Gramicidin S(Bacteriocin)	No entry found	Not found	Not found	Bacillus brevis	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Beta sheet	"The second and seventh residues of this cyclic peptide are Ornithines, an analog of lysine (one CH2 shorter). They are represented here with lysines. In addition, residue F is a D-amino acid."	None	"Function: This is the first cyclic peptide antibiotic used clinically. For gram-negative bacteria, however,  activity  was strongly dependent on whether the assay was carried out in solution or in agar. It was found that GS was active against gram-negative microorganisms in the solution-based  assay, but inactive against these using an agar-based  assay. GS was also found to have antifungal activity when measured using a  liquid-broth assay. "	"Gram-positive, Gram-negative (broad-spectrum)"	It exhibits hemolytic activity at 25 ¦ÌM and 45 ¦ÌM against human red cells and sheep red cells.	Cyclic	No specific N-terminal	No specific C-terminal	The 'O' in sequence is Ornithine	Mixed(D-Phe)	No cytotoxicity information found	Cell membrane	8836773##24388950	Int J Pept Protein Res. 1996 Jun;47(6):460-6.##Biochim Biophys Acta. 2014 May;1838(5):1420-9. 	"Kondejewski LH, Farmer SW, Wishart DS, Hancock RE, Hodges RS.##Abraham T, Prenner EJ, Lewis RN, Mant CT, Keller S, Hodges RS, McElhaney RN."	"Gramicidin S is active against both gram-positive and gram-negative bacteria.##Structure-activity relationships of the antimicrobial peptide gramicidin S and its analogs: aqueous solubility, self-association, conformation, antimicrobial activity and interaction with model lipid membranes."
DRAMP03322	HPLKQYWWRPSI	12	PW2	No entry found	Not found	Not found	Phage display peptide library	"Antimicrobial, Antifungal"	Not found	Non helix or strand structure	"In the absence of an interface, PW2 is in random coil conformation. In micelles, structural calculation shows that Trp-7 forms the hydrophobic core that is important for the peptide folding. Lys-4, Tyr-6, Trp-8, and Arg-9 are in the same surface, possibly facing the micelle interface. (Ref.2)"	1M02 resolved by NMR.	Function: Synthetic PW2 shows anticoccidial activity against E. acervulina and Eimeria tenella with very low hemolytic activity. It also displays antifungal activity but no activity against bacteria.(Ref.2)	"Fungi: Eimeria acervulina sporozoites, E. tenella sporozoites, Toxoplasma gondii tachyzoites (low activity)."	"[Ref.11849705]1.60% hemolytic activity at 100 ¦ÌM against human erythrocytes,1.57% hemolytic activity at 100 ¦ÌM against rabbit erythrocytes,1.42% hemolytic activity at 100 ¦ÌM against chicken erythrocytes,"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11849705##12130641	Mol Biochem Parasitol. 2002 Mar;120(1):53-60.## Biol Chem. 2002 Sep 27;277(39):36351-6.	"da Silva A Jr, Kawazoe U, Freitas FF, Gatti MS, Dolder H, Schumacher RI, Juliano MA, da Silva MJ, Leite A.##co LW, Da Silva A Jr, Leite A, Valente AP, Almeida FC."	Avian anticoccidial activity of a novel membrane-interactive peptide selected from phage display libraries.##NMR structure of PW2 bound to SDS micelles. A tryptophan-rich anticoccidial peptide selected from phage display libraries.
DRAMP03327	PSELEKALSNLIDVYHNYSNIQGNHHALYKNDFKKMVTTECPQFVQNINIENLFRELDINSDNAINFEEFLAMVIKVGVASHKDSHKE	88	"Protein S100-A8 (Calgranulin-A; MRP-8; Rodents, mammals, animals)"	"P27005, P31724"	Belongs to the S-100 family	S100a8	Mus musculus (Mouse)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn2+ which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect.
Disruption phenotype: Death at an early embryonic stage due to embryo resorption, starting about 8 days after fertilization.
Miscellaneous: Binds two calcium ions per molecule with an affinity similar to that of the S100 proteins (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Metal-binding	1373330##17767165##18403730	Blood. 1992 Apr 15;79(8):1907-15.##Nat Med. 2007 Sep;13(9):1042-9.##Circ Res. 2008 May 23;102(10):1239-46.	"Lagasse E, Weissman IL.##Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J.##Boyd JH, Kan B, Roberts H, Wang Y, Walley KR."	"Mouse MRP8 and MRP14, two intracellular calcium-binding proteins associated with the development of the myeloid lineage.##Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.##S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end products."
DRAMP03366	DQYKCLQHGGFCLRSSCPSNTKLQGTCKPDKPNCCKS	37	"Beta-defensin 1 (BD-1; mBD-1; Defensin, beta 1; Rodents, mammals, animals)"	P56386	Belongs to the beta-defensin family	Not found	Mus musculus (Mouse)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Bridge	Not found	None	PTM: Contains three disulfide bonds 5-34; 12-27; 17-35.	"Gram-negative bacteria: Escherichia coli, Pseudomonas aeruginosa;##Gram-positive bacterium: Staphylococcus aureus."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9287114	FEBS Lett. 1997 Aug 11;413(1):45-49.	"Huttner KM, Kozak CA, Bevins CL."	The mouse genome encodes a single homolog of the antimicrobial peptide human beta-defensin 1.
DRAMP03371	KTINNPVSCCMIGGICRYLCKGNILQNGNCGVTSLNCCKRK	41	"Beta-defensin 5 (BD-5, mBD-5; Defensin, beta 5; Rodents, mammals, animals)"	Q9EPV9	Belongs to the beta-defensin family	Defb5	Mus musculus (Mouse)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Bridge	Not found	None	PTM: Contains three disulfide bonds 9-37; 16-30; 20-38.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases	"Adler D.A, Holloway J.L, Haldeman B.E, Rixon M, Jaspers S, Fox B, Gosink J, Sheppard P, Presnell S, Gao Z, Whitmore T, Stamm M, Laube D, Diamond G."	EST and genomic database mining yield novel human and mouse beta-defensins
DRAMP03379	FLPKTLRKFFCRIRGGRCAVLNCLGKEEQIGRCSNSGRKCCRKKK	45	"Beta-defensin 14 (BD-14, mBD-14; Defensin, beta 14; Rodents, mammals, animals)"	"Q7TNV9, Q14BD1"	Belongs to the beta-defensin family	Not found	Mus musculus (Mouse)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Bridge	Not found	None	PTM: Contains three disulfide bonds 11-40; 18-33; 23-41.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15489334##18167348	Genome Res. 2004 Oct;14(10B):2121-2127.##J Biol Chem. 2008 Feb 29;283(9):5414-5419.	"Gerhard DS, Wagner L, et al.##R?hrl J, Yang D, Oppenheim JJ, Hehlgans T."	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).##Identification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3."
DRAMP03408	VTCFCRRRGCASRERHIGYCRFGNTIYRLCCRR	33	"Neutrophil defensin 1 (HANP-1; alpha-defensin; Rodents, mammals, animals)"	P81465	Belongs to the alpha-defensin family	Not found	Mesocricetus auratus (Golden hamster)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Function: Anti-fungal and bactericidal activity, greater against Gram-positive bacteria."	"Gram-positive bacteria: Staphylococcus aureus, Streptococcus pyogenes, Enterococcus faecalis;##Gram-negative bacteria: Escherichia coli, Salmonella serotype krefeld, Klebsiella oxytoca, Pseudomonas aeruginosa.##Fungi: Candida albicans, Cryptococcus neoformans."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys3 and Cys31,Cys5 and Cys20,Cys10 and Cys30."	L	No cytotoxicity information found	Not found	8890190	Infect Immun. 1996 Nov;64(11):4444-4449.	"Mak P, W¨®jcik K, Thogersen IB, Dubin A."	"Isolation, antimicrobial activities, and primary structures of hamster neutrophil defensins."
DRAMP03409	CFCKRPVCDSGETQIGYCRLGNTFYRLCCRQ	31	"Neutrophil defensin 2 (HANP-2; alpha-defensin; Rodents, mammals, animals)"	P81466	Belongs to the alpha-defensin family	Not found	Mesocricetus auratus (Golden hamster)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Function: Bactericidal activity, greater against Gram-positive bacteria. Low anti-fungi activity"	"Gram-positive bacteria: Staphylococcus aureus, Streptococcus pyogenes, Enterococcus faecalis;##Gram-negative bacteria: Escherichia coli, Salmonella serotype krefeld, Klebsiella oxytoca, Pseudomonas aeruginosa.##Fungi: Candida albicans, Cryptococcus neoformans."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Cyclization(Cys1 and Cys29).	Free	"Disulfide bonds between Cys1 and Cys29,Cys3 and Cys18,Cys8 and Cys28."	L	No cytotoxicity information found	Not found	8890190	Infect Immun. 1996 Nov;64(11):4444-4449.	"Mak P, W¨®jcik K, Thogersen IB, Dubin A."	"Isolation, antimicrobial activities, and primary structures of hamster neutrophil defensins."
DRAMP03410	VTCFCRRRGCASRERLIGYCRFGNTIYGLCCRR	33	"Neutrophil defensin 3 (HANP-3; alpha-defensin; Rodents, mammals, animals)"	P81467	Belongs to the alpha-defensin family	Not found	Mesocricetus auratus (Golden hamster)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Function: Anti-fungal and bactericidal activity, greater against Gram-positive bacteria."	"Gram-positive bacteria: Staphylococcus aureus, Streptococcus pyogenes, Enterococcus faecalis;##Gram-negative bacteria: Escherichia coli, Salmonella serotype krefeld, Klebsiella oxytoca, Pseudomonas aeruginosa.##Fungi: Candida albicans, Cryptococcus neoformans."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys3 and Cys31,Cys5 and Cys20,Cys10 and Cys30."	L	No cytotoxicity information found	Not found	8890190	Infect Immun. 1996 Nov;64(11):4444-4449.	"Mak P, W¨®jcik K, Thogersen IB, Dubin A."	"Isolation, antimicrobial activities, and primary structures of hamster neutrophil defensins."
DRAMP03411	VTCFCKRPVCDSGETQIGYCRLGNTFYRLCCRQ	33	"Neutrophil defensin 4 (HANP-4; alpha-defensin; Rodents, mammals, animals)"	P81468	Belongs to the alpha-defensin family	Not found	Mesocricetus auratus (Golden hamster)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Function: Bactericidal activity, greater against Gram-positive bacteria. Low anti-fungi activity."	"Gram-positive bacteria: Staphylococcus aureus, Streptococcus pyogenes, Enterococcus faecalis;##Gram-negative bacteria: Escherichia coli, Salmonella serotype krefeld, Klebsiella oxytoca, Pseudomonas aeruginosa.##Fungi: Candida albicans, Cryptococcus neoformans."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys3 and Cys31,Cys5 and Cys20,Cys10 and Cys30."	L	No cytotoxicity information found	Not found	8890190	Infect Immun. 1996 Nov;64(11):4444-4449.	"Mak P, W¨®jcik K, Thogersen IB, Dubin A."	"Isolation, antimicrobial activities, and primary structures of hamster neutrophil defensins."
DRAMP03420	VTCYCRSTRCGFRERLSGACGYRGRIYRLCCR	32	"Neutrophil antibiotic peptide NP-2 (RatNP-2; Rodents, mammals, animals)"	Q62715	Belongs to the alpha-defensin family	Defa	Rattus norvegicus (Rat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Active in vitro against S. aureus, fungi, Gram-positive and Gram-negative bacteria and to a lesser extent against an enveloped virus."	Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacterium: Salmonella typhimurium.	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys3 and Cys31,Cys5 and Cys20,Cys10 and Cys30."	L	No cytotoxicity information found	Not found	2254017##7594610	Infect. Immun. 1990;58:3899-3902.##J. Immunol. 1995;155:4476-4484. 	"Eisenhauer P.B, Harwig S.S.S.L, Szklarek D, Ganz T, Lehrer R.I.##Yount N.Y, Wang MS.C, Yuan J, Banaiee N, Ouellette A.J, Selsted M.E."	Polymorphic expression of defensins in neutrophils from outbred rats.##Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis.
DRAMP03421	CSCRTSSCRFGERLSGACRLNGRIYRLCC	29	"Neutrophil antibiotic peptide NP-3 (RatNP-3a, RatNP-3b; Rodents, mammals, animals)"	"Q62713, Q9Z1F1"	Belongs to the alpha-defensin family	Not found	Rattus norvegicus (Rat)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral"	Protein level	Bridge	Not found	None	"Active in vitro against S. aureus, fungi, Gram-positive and Gram-negative bacteria and to a lesser extent against an enveloped virus."	"Gram-positive bacterium: Staphylococcus aureus 502A;##Gram-negative bacterium: Escherichia coli ML-35.##Fungi: Candida albicans 820, Cryptococcus neoformans A-383."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Cyclization(Cys1 and Cys29).	Cyclization(Cys1 and Cys29).	"Disulfide bonds between Cys1 and Cys29,Cys3 and Cys18,Cys8 and Cys28."	L	No cytotoxicity information found	Not found	2254017##7594610	Infect. Immun. 1990;58:3899-3902.##J. Immunol. 1995;155:4476-4484. 	"Eisenhauer P.B, Harwig S.S.S.L, Szklarek D, Ganz T, Lehrer R.I.##Yount N.Y, Wang MS.C, Yuan J, Banaiee N, Ouellette A.J, Selsted M.E."	Polymorphic expression of defensins in neutrophils from outbred rats.##Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis.
DRAMP03462	ATELEKALSNVIEVYHNYSGIKGNHHALYRDDFRKMVTTECPQFVQNKNTESLFKELDVNSDNAINFEEFLVLVIRVGVAAHKDSHKE	88	"Protein S100-A8 (Calgranulin-A; MRP-8; Rodents, mammals, animals)"	P50115	Belongs to the S-100 family	S100a8	Rattus norvegicus (Rat)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn2+ which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect.
Miscellaneous: Binds two calcium ions per molecule with an affinity similar to that of the S100 proteins (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Metal-binding	21487906	Inflammation. 2012 Apr;35(2):409-419.	"Koike A, Arai S, Yamada S, Nagae A, Saita N, Itoh H, Uemoto S, Totani M, Ikemoto M."	Dynamic mobility of immunological cells expressing S100A8 and S100A9 in vivo: a variety of functional roles of the two proteins as regulators in acute inflammatory reaction.
DRAMP03466	PRGSPRTEYEAARR	14	Ribosome-inactivating protein luffacylin (rRNA N-glycosidase; Plants)	P84073	Not found	Not found	Luffa cylindrica (Smooth loofah) (Sponge gourd)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity against F. oxysporum and M. arachidicola. Inhibits cell-free translation in rabbit reticulocyte lysate system. Has some N-glycosidase activity.
Catalytic activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA."	"Fungi: Mycosphaerella arachidicola, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12126727	Peptides. 2002 Jun;23(6):1019-10124.	"Parkash A, Ng TB, Tso WW."	"Isolation and characterization of luffacylin, a ribosome inactivating peptide with anti-fungal activity from sponge gourd (Luffa cylindrica) seeds."
DRAMP03468	GVCDMADLA	9	Alveolarin (Fungus)	P84760	Not found	Not found	Polyporus alveolaris (Hexagonal-pored polypore) (Favolus alveolaris)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Antifungal activity. Inhibits mycelial growth of F. cinera, F. oxysporum, M. arachidicola and P. piricola. Lacks protease, ribonuclease, deoxyribonuclease and hemagglutinating activity."	"Fungi: Botrytis cinerea, Fusarium oxysporum, Mycosphaerella arachidicola and Physalospora piricola."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15165727	Peptides. 2004 Apr;25(4):693-696.	"Wang H, Ng TB, Liu Q."	"Alveolarin, a novel antifungal polypeptide from the wild mushroom Polyporus alveolaris."
DRAMP03473	DNGEAGRAAR	10	Antimicrobial ribonuclease (Fungus)	P84528	Not found	Not found	Pleurotus sajor-caju (Oyster mushroom)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has ribonuclease activity towards yeast tRNA and polyuracil and weak ribonuclease activity towards other polyhomoribonucleotides. Has weak deoxyribonuclease activity. Displays antimitogenic activity towards murine splenocytes and antiproliferative activity towards HepG2 hepatoma cells and L1210 leukemia cells.
Biophysicochemical properties: pH dependence (Optimum pH is from 5.5 to 6.0); Temperature dependence (Optimum temperature below 60 degrees Celsius. Active from 0 to 100 degrees Celsius)."	"Bacteria: Pseudomonas aeruginosa, Pseudomonas fluorescens, Staphylococcus aureus.##Fungi: Fusarium oxysporum (IC50=95 ?M), Mycosphaerella arachidicola (IC50=72 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15003351	Peptides. 2004 Jan;25(1):11-17.	"Ngai PH, Ng TB."	"A ribonuclease with antimicrobial, antimitogenic and antiproliferative activities from the edible mushroom Pleurotus sajor-caju."
DRAMP03475	QCMQLETSGQMRRCVSQCDKRFEEDIDWSKYDNQE	35	Vicilin-like Antimicrobial peptide 2a (MiAMP2a; Plant defensin)	Q9SPL3	Belongs to the vicilin-like family	AMP2-3	Macadamia integrifolia (Macadamia nut)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml).##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5-10 ?g/ml), Chalara elegans (IC50=2-5, 10-20 ?g/ml), Fusarium oxysporum (IC50=10, 20-50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10-25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10571855	Plant J. 1999 Sep;19(6):699-710.	"Marcus JP, Green JL, Goulter KC, Manners JM."	A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels.
DRAMP03476	ATRVVYCNRRSGSVVGGDDTVYYEG	25	"Eryngin (mushroom, fungi)"	P84525	Not found	Not found	Pleurotus eryngii 	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Comment: No comments found on DRAMP database	"Fungi: Fusarium oxysporum, Mycosphaerella arachidicola."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15003349	Peptides. 2004 Jan;25(1):1-5.	"Wang H, Ng TB."	"Eryngin, a novel antifungal peptide from fruiting bodies of the edible mushroom Pleurotus eryngii."
DRAMP03478	AGETHTVMINHAGRGAPKLVVGGKKLS	27	Ganodermin (Fungus)	P84995	Not found	Not found	Ganoderma lucidum (Ling zhi medicinal fungus) (Bracket fungus)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antifungal activity. Lacks hemagglutinating activity towards rabbit erythrocytes. Lacks deoxyribonuclease, ribonuclease and protease inhibitory activities."	"Fungi: Botrytis cinerea (IC50=15.2 ?M), Fusarium oxysporum (IC50=12.4 ?M), Physalospora piricola (IC50=18.1 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16039755	Peptides. 2006 Jan;27(1):27-30. Epub 2005 Jul 21.	"Wang H, Ng TB."	"Ganodermin, an antifungal protein from fruiting bodies of the medicinal mushroom Ganoderma lucidum"
DRAMP03492	DKLIGSCVWGAVNYTSDCNGECLLRGYKGGHCGSFANVNCWCET	44	"Defensin heliomicin (Mutation: K23L, R24L)"	P81544	Belongs to the invertebrate defensin family (Type 2 subfamily)	Not found	Heliothis virescens (tobacco budworm)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Combine helix and strand structure	Not found	1I2V resolved by NMR. 	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11580275	Biochemistry. 2001 Oct 9;40(40):11995-12003.	"Lamberty M, Caille A, Landon C, Tassin-Moindrot S, Hetru C, Bulet P, Vovelle F."	Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities.
DRAMP03494	WKPFKKIEKAVRRVRDGVAKAGPAVAVVGQAT	32	"Cecropin (Insects, animals)"	P83420	Not found	Not found	Oiketicus kirbyi (Bagworm moth)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria. Has also activity against fungi	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUL-2002) to UniProtKB	Bulet P.	Unknown
DRAMP03495	INNWVRVPPCDQVCSRTNPEKDECCRAHGHAFHATCSGGMQCYRR	45	"Psychimicin (Insects, animals)"	P83421	Not found	Not found	Oiketicus kirbyi (Bagworm moth)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity. Is particularly active against fungi, and to a lesser extent against Gram-positive and Gram-negative bacteria.
Tissue specificity: Hemolymph.
PTM: Contains three disulfide bonds 10-24; 14-36; 25-42."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUL-2002) to UniProtKB	Bulet P.	Unknown
DRAMP03496	RWKVFKKIEKVGRNIRDGVIKAAPAIEVLGQAKAL	35	"Cecropin-A (Insects, animals)"	P83413	Not found	Not found	Heliothis virescens (Tobacco budworm moth)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria. Has also activity against fungi.
Tissue specificity: Hemolymph. Induction: By bacterial infection.
PTM: C-terminal amidation."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted JUL-2002 to the SWISS-PROT data bank.	"Bulet P, Lamberty M, Brookhart G, Bushey D."	Unknown
DRAMP03497	KWKVFKKIEKVGRNIRDGIVKAGPAIAVLGQAN	33	"Cecropin-B (Insects, animals)"	P83414	Belongs to the cecropin family	Not found	Heliothis virescens (Tobacco budworm moth)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria. Has also activity against fungi.
Induction: By bacterial infection."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUL-2002) to UniProtKB.	"Bulet P, Lamberty M, Brookhart G, Bushey D."	Unknown
DRAMP03498	RWKVFKKIEKMGRNIRDGVIKAAPAIEVLGQAK	33	"Cecropin-C (Insects, animals)"	P83415	Belongs to the cecropin family	Not found	Heliothis virescens (Tobacco budworm moth)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria. Has also activity against fungi.
Induction: By bacterial infection."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUL-2002) to UniProtKB.	"Bulet P, Lamberty M, Brookhart G, Bushey D."	Unknown
DRAMP03501	AIGCNTVASKMAPCLPYVTGKGPLGGCCGGVKGLIDAARTTPDRQAVCNCLKTLAKSYSGINLGNAAGLPGKCGVSIPYQISPNTDCSKVH	91	"La-LTP (LJAFP; Insects, animals)"	Q52RN7	Not found	Afp	Leonurus japonicus (Chinese motherwort) (Leonurus artemisia)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).	"Gram-positive Bacteria: Bacillus subtilis (IC50>15 ?M). ##Gram-negative Bacteria: Pseudomonas solanacearum (IC50=7.5-15 ?M), Ralstonia solanacearum (IC50=15 ?M).##Fungi: Alternaria alternate (IC50<7.5 ?M), Alternaria brassicae (IC50<7.5 ?M), Aspergillus niger (IC50<7.5 ?M), Bipolaris maydis (IC50<7.5 ?M), Botrytis cinerea (IC50=7.5-15 ?M), Cerospora personata (IC50=7.5-15 ?M), Colletotrichum gloeosporiodes (IC50<7.5 ?M), Fusarium graminearum (IC50=7.5-15 ?M), Fusarium oxysporum (IC50=7.5-15 ?M), Penicillium digitatum (IC50>15 ?M), Pyricularia grisea (IC50=7.5-15 ?M), Rhizoctonia solani (IC50<7.5 ?M), Rhizoctonia cerealis (IC50=7.5-15 ?M), Saccharomyces cerevisiae (IC50>15 ?M), Sclerotinia sclerotiorum (IC50>15 ?M), Trichoderma harzianum (IC50=7.5-15 ?M), Verticillium dahliae (IC50=7.5-15 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	PubMed ID is not available	Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases	"Yang X, Xiao Y, Pei Y, Zhen C."	"LJAFP, a novel non-specific lipid transfer protein-like antimicrobial protein from motherwort (Leonurus japonicus) confers disease resistance against phytopathogenic fungi and bacterium in transgenic tobacco."
DRAMP03522	MKIAFIVAISLAFLAVTSCIEFEKSTESHDIQKRGVTITVKPPFPGCVFYECIANCRSRGYKNGGYCTINGCQCLR	76	"Gallerimycin (defensins; Insects, animals)"	Q8MVY9	Not found	Not found	Galleria mellonella (Greater wax moth)	"Antimicrobial, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	Metarhizium anisopliae	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12811766	Arch Insect Biochem Physiol. 2003 Jul;53(3):125-133.	"Schuhmann B, Seitz V, Vilcinskas A, Podsiadlowski L."	"Cloning and expression of gallerimycin, an antifungal peptide expressed in immune response of greater wax moth larvae, Galleria mellonella."
DRAMP03557	GRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRLCIPSTGPL	83	"Granulysin (Lymphokine LAG-2; Human, mammals, animals)"	P22749	Not found	GNLY	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Antifungal, Antiparasitic"	Protein level	Alpha helix	Not found	1L9L resolved by X-ray.	"Function: Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.
Tissue specificity: Expressed in natural killer and T-cells.
Induction: By T-cell growth factor and IL2/interleukin-2."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9756476##12488100	Science. 1998 Oct 2;282(5386):121-125.##J Mol Biol. 2003 Jan 10;325(2):355-365.	"Stenger S, Hanson DA, Teitelbaum R, Dewan P, Niazi KR, Froelich CJ, Ganz T, Thoma-Uszynski S, Meli¨¢n A, Bogdan C, Porcelli SA, Bloom BR, Krensky AM, Modlin RL.##Anderson DH, Sawaya MR, Cascio D, Ernst W, Modlin R, Krensky A, Eisenberg D."	An antimicrobial activity of cytolytic T cells mediated by granulysin.##Granulysin crystal structure and a structure-derived lytic mechanism.
DRAMP03564	ICIFCCGCCHRSKCGMCCKT	20	"Human hepcidin-20 (Hepc20; one chain of Hepcidin; Human, mammals, animals)"	"P81172, Q1HE14, Q9BY68"	Not found	HAMP	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Beta strand	Not found	1M4E resolved by NMR.	"Function: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa.
Tissue specificity: Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine.
PTM: Contains four disulfide bonds 2-18; 5-17; 6-14; 8-9."	"Gram-negative bacterium: Escherichia coli;##Gram-positive bacteria: Staphylococcus aureus, S. epidermidis, group B Streptococcus.##Fungi: Candida albicans, Aspergillus fumigatus, Aspergillus niger."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11113131##12138110##11034317	J Biol Chem. 2001 Mar 16;276(11):7806-7810.##J Biol Chem. 2002 Oct 4;277(40):37597-37603.##FEBS Lett. 2000 Sep 1;480(2-3):147-150.	"Park CH, Valore EV, Waring AJ, Ganz T.##Hunter HN, Fulton DB, Ganz T, Vogel HJ.##Krause A et al Adermann K."	"Hepcidin, a urinary antimicrobial peptide synthesized in the liver.##The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis.##LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. ref2) Hepcidin, a rinary antimicrobial peptide synthesized in the liver."
DRAMP03565	DTHFPICIFCCGCCHRSKCGMCCKT	25	"Human hepcidin-25 (Hepc25; one chain of Hepcidin; Human, mammals, animals)"	"P81172, Q1HE14, Q9BY68"	Not found	HAMP	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Beta strand	N-terminus is a metal-binding site. disulfide bonds are essential for antibacterial activity by probably binding to DNA.	"1M4F, 2KEF resolved by NMR.##3H0T resolved by X-ray."	"PTM: Contains four disulfide bonds 7-22; 10-13; 11-19; 14-22.
Tissue specificity: Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine.
Function: It showed antimicrobial activities in vitro, this peptide might be the long-sought hormone that regulates iron homeostasis in humans. A pathogen will survive if it can figure out a way to steal iron from the host."	"Gram-negative bacterium: Escherichia coli;##Gram-positive bacteria: Staphylococcus aureus, S. epidermidis, group B Streptococcus.##Fungi: Candida albicans, Aspergillus fumigatus, Aspergillus niger."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	DNA	11034317##11113131##12138110##19553669	FEBS Lett. 2000 Sep 1;480(2-3):147-150.##J Biol Chem. 2001 Mar 16;276(11):7806-7810.##J Biol Chem. 2002 Oct 4;277(40):37597-37603.##J Biol Chem. 2009 Sep 4;284(36):24155-24167.	"Krause A et al Adermann K.##Park CH, Valore EV, Waring AJ, Ganz T.##Hunter HN, Fulton DB, Ganz T, Vogel HJ.##Jordan JB, Poppe L, Haniu M, Arvedson T, Syed R, Li V, Kohno H, Kim H, Schnier PD, Harvey TS, Miranda LP, Cheetham J, Sasu BJ."	"LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. ref2) Hepcidin, a rinary antimicrobial peptide synthesized in the liver.##Hepcidin, a urinary antimicrobial peptide synthesized in the liver.##The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis.##Hepcidin revisited, disulfide connectivity, dynamics, and structure."
DRAMP03576	DSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN	38	"Histatin-1 (His-rich; Human, mammals, animals)"	P15515 	Not found	HTN1	Homo sapiens (Human)	"Antimicrobial, Antifungal"	Protein level	Rich	Not found	None	"PTM: Phosphoserine at position 2; And Sulfotyrosine at position 27,30,34,36."	Yeast: Candida albicans (99.5¡À0.5 % inhibition at 54 nmol).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	3286634	J Biol Chem. 1988 Jun 5;263(16):7472-7477	"Oppenheim FG, Xu T, McMillian FM, Levitz SM, Diamond RD, Offner GD, Troxler RF."	"Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans."
DRAMP03577	RKFHEKHHSHREFPFYGDYGSNYLYDN	27	"Histatin-2 (His-rich; Human, mammals, animals)"	"P15516, Q16243, Q502Z1"	Not found	HTN3	Homo sapiens (Human)	"Antimicrobial, Antifungal"	Protein level	Rich	Not found	None	An autoproteolytic product from Histatin 1 but not phosphorylated (Lal et al. 1992 Arch Oral Bio 37: 7-13). 	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1528633	Oral Microbiol Immunol 1992; 7: 127-128.	"Xu L, Lal K, Pollock JJ."	Histatins 2 and 4 are autoproteolytic degradation products of human parotid saliva.
DRAMP03578	DSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN	32	"Histatin-3 (His-rich; Human, mammals, animals)"	"P15516, Q16243, Q502Z1"	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Rich	Not found	None	Comment: No comments found on DRAMP database	Yeast: Candida albicans (98.5¡À0.5 % inhibition at 54 nmol)	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	3286634	J Biol Chem. 1988 Jun 5;263(16):7472-7477	"Oppenheim FG, Xu T, McMillian FM, Levitz SM, Diamond RD, Offner GD, Troxler RF1988"	"Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans."
DRAMP03579	RKFHEKHHSHRGYRSNYLYDN	21	"Histatin-4 (His-rich; Human, mammals, animals)"	"P15516, Q16243, Q502Z1"	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antifungal"	Protein level	Rich	Not found	None	An autoproteolytic product from Histatin 3.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	1528633	Oral Microbiol Immunol 1992; 7: 127-128.	"Xu L, Lal K, Pollock JJ."	Histatins 2 and 4 are autoproteolytic degradation products of human parotid saliva.
DRAMP03580	DSHAKRHHGYKRKFHEKHHSHRGY	24	His3-(20-43)-peptide (Histatin 5; derivatives: Dh-5; Clinical)	"P15516, Q16243, Q502Z1"	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Alpha helix 	Not found	None	"Histatin 5 is a proteolytic product of histatin 3. The active Domain: of histitin 5 (Dh-5) corresponding to residues 11-24 showed HIV inhibitory effects. However,the results with the Dh-5 mutants are mixed (Groot et al. 2006 J. Virol. 80: 9236-9243). The sequence of Dhvar4 is KRLFKKLLFSLRKY, a helical peptide which is active against bacteria and fungi. Dhvar5 has a sequence LLLFLLKKRKKRKY, which is active against bacteria and fungi (Ruissen AL et al 2002 Peptides 23:1391-9). P-113 is a 12-residue active peptide corresponding to residues 4-15 of histatin 5 (Rothstein DM et al. 2001 AAC 45: 1367). The His-His sequence is a good ligand for Cu2+ (Kulon K et al. 2008 J Inorg Biochem 102: 960-72). Derivatives were subjected to clinical trials."	"Yeast: Candida albicans (100% inhibition at 54 nmol), Cryptococcus neoformans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Metal-binding (Zinc)	3286634	J Biol Chem. 1988 Jun 5;263(16):7472-7477.	"Oppenheim FG, Xu T, McMillian FM, Levitz SM, Diamond RD, Offner GD, Troxler RF."	"Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans."
DRAMP03581	DSHAKRHHGYKRKFHEKHHSHRGYR	25	"Histatin 6 (His-rich; Human, mammals, animals)"	"P15516, Q16243, Q502Z1"	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antifungal"	Protein level	Rich	Not found	None	An autoproteolytic product from Histatin 3.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	J Dent Res 1990; 69: 2-6.	Troxler RF et al Oppenheim FG.	Structural relation between human salivary histatins.
DRAMP03582	RKFHEKHHSHRGY	13	"Histatin 7 (His-rich; Human, mammals, animals)"	"P15516, Q16243, Q502Z1"	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antifungal"	Protein level	Rich	Not found	None	An autoproteolytic product from Histatin 3 (residues 12-24).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	J Dent Res 1990; 69: 2-6.	Troxler RF et al Oppenheim FG.	Structural relation between human salivary histatins.
DRAMP03583	KFHEKHHSHRGY	12	"Histatin 8 (His-rich; Human, mammals, animals)"	"P15516, Q16243, Q502Z1"	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Rich	Not found	None	It is the fragment of histatin 5.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12711380	Arch Oral Biol 2003 May;48(5):361-368.	"Yin A, Margolis HC, Grogan J, Yao Y, Troxler RF, Oppenheim FG."	Physical parameters of hydroxyapatite adsorption and effect on candidacidal activity of histatins.
DRAMP03584	RKFHEKHHSHRGYR	14	"Histatin 9 (His-rich; Also detected are Histatin 10; Human, mammals, animals)"	No entry found	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antifungal"	Not found	Rich	Not found	None	An autoproteolytic product from Histatin 3 (residues 12-25). Histatin 12=residues 5-10; histatin 11=residues 5-11; Histatin 10=residues 13-25. Antimicrobial activities of Histatins 10-12 are Comment: No comments found on DRAMP databasen. 	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Oral Microbiol Immunol 1992; 7: 127-128.	"Xu L, Lal K, Pollock JJ."	Histatins 2 and 4 are autoproteolytic degradation products of human parotid saliva.
DRAMP03585	AELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDES	68	"Human TC-1 (Chain of Platelet basic protein; Human, mammals, animals)"	"P02775, B2R5F3, Q6IBJ8"	Not found	PPBP	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Combine helix and strand structure	Not found	1TVX resolved by X-ray.	PTM: Contains two disulfide bonds 5-31; 7-46.	"Gram-positive bacteria: Bacillus subtilis (MBC=0.4 ?M), Staphylococcus aureus (MBC=6.8 ?M);##Gram-negative bacterium: Escherichia coli (MBC=3.4 ?M).##Fungi: Cryptococcus neoformans (MFC=1.9 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10877842##8034022	J Biol Chem. 2000 Jul 7;275(27):20374-20381.##FEBS Lett. 1994 Jun 27;347(2-3):300-303.	"Krijgsveld J, Zaat SA, Meeldijk J, van Veelen PA, Fang G, Poolman B, Brandt E, Ehlert JE, Kuijpers AJ, Engbers GH, Feijen J, Dankert J.##Kungl AJ, Machius M, Huber R, Schwer C, Lam C, Aschauer H, Ehn G, Lindley IJ, Auer M."	"Thrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokines.##Purification, crystallization and preliminary X-ray diffraction analysis of recombinant human neutrophil-activating peptide 2 (rhNAP-2)."
DRAMP03586	NLAKGKEESLDSDLYAELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDES	83	"Human TC-2 (Chain of Platelet basic protein; Human, mammals, animals)"	"P02775, B2R5F3, Q6IBJ8"	Not found	PPBP	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Combine helix and strand structure	Not found	1F9P resolved by X-ray.	PTM: Contains two disulfide bonds 19-46; 22-62.	"Gram-positive bacteria: Bacillus subtilis ATCC6633 (MBC=0.7 ?M), Staphylococcus aureus 42D (MBC=11 ?M);##Gram-negative bacterium: Escherichia coli ML35 (MBC=2.7 ?M).##Fungi: Cryptococcus neoformans (MFC=30 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10877842##8034022	J Biol Chem. 2000 Jul 7;275(27):20374-20381.##FEBS Lett. 1994 Jun 27;347(2-3):300-303.	"Krijgsveld J, Zaat SA, Meeldijk J, van Veelen PA, Fang G, Poolman B, Brandt E, Ehlert JE, Kuijpers AJ, Engbers GH, Feijen J, Dankert J.##Kungl AJ, Machius M, Huber R, Schwer C, Lam C, Aschauer H, Ehn G, Lindley IJ, Auer M."	"Thrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokines.##Purification, crystallization and preliminary X-ray diffraction analysis of recombinant human neutrophil-activating peptide 2 (rhNAP-2)."
DRAMP03587	SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSV	47	"DCD-1 (chain of Dermcidin; Human, mammals, animals)"	"P81605, A5JHP2, A5JHP3, P58461, Q53YJ2"	Not found	DCD	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Proteolytic"	Protein level	Alpha helix 	"Structural analysis of dermcidin-1L in 50% TFE using an N15-labeled recombinant peptide reveals a long helix-hinge-helix motif, allowing it to associate with bacterial membranes (Jung et al. 2010 BMB Rep. 43: 362-8). "	2KSG resolved by NMR.##2YMK resolved by X-ray.	"Function: DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity. Survival-promoting peptide promotes survival of neurons and displays phosphatase activity.
Catalytic activity: Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
Cofactor: Manganese. Required for survival-promoting peptide.
Tissue specificity: Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml."	"Gram-negative bacteria: Escherichia coli, Enterococcus faecalis;##Gram-positive bacterium: Staphylococcus aureus.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	May bind IgG	11694882##17448443##20510021	Nat Immunol. 2001 Dec;2(12):1133-1137.##Biochem Biophys Res Commun. 2007 Jun 15;357(4):828-833.##BMB Rep. 2010 May;43(5):362-368.	"Schittek B, Hipfel R, Sauer B, Bauer J, Kalbacher H, Stevanovic S, Schirle M, Schroeder K, Blin N, Meier F, Rassner G, Garbe C.##Lee Motoyama JP, Kim-Motoyama H, Kim P, Nakagama H, Miyagawa K, Suzuki K.##Jung HH, Yang ST, Sim JY, Lee S, Lee JY, Kim HH, Shin SY, Kim JI."	Dermcidin: a novel human antibiotic peptide secreted by sweat glands.##Identification of dermcidin in human gestational tissue and characterization of its proteolytic activity.##Analysis of the solution structure of the human antibiotic peptide dermcidin and its interaction with phospholipid vesicles.
DRAMP03588	LAHQKPFIRKSYKCLHKRCR	20	"Human MUC7 20-Mer (Human, mammals, animals)"	No entry found	Not found	Not found	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix 	Not found	None	"Function: MUC7 20-mer showes potent activity against a variety of fungi, including C. albicans, C. glabrata, C. krusei, C. neoformans, and S. cerevisae. In addition, it is also active against several drug-resistant strains, including azole-resistant C. albicans, fluconazole-resistant C. glabrata, and amphotericin B-resistant C. neoformans."	"Gram-positive bacteria: Streptococcus mutans (EC50=1.39 ?M), Streptococcus gordonii (EC50=2.43 ?M);##Gram-negative bacteria: Escherichia coli (EC50=1.61 ?M), Pseudomonas aeruginosa (EC50=4.41 ?M), Porphyromonas gingivalis (EC50<1 ?M).##Fungi: Candida albicans (DIS) (EC50=5.85 ?M), C. albicans (azole resistant) (EC50=2.40 ?M), Candida glabrata (EC50=5.02 ?M), C. glabrata (fluconazole resistant) (EC50=12.3 ?M), Candida krusei (EC50=5.16 ?M), Cryptococcus neoformans (EC50=4.05 ?M), Cryptococcus neoformans (amphotericin B resistant) (EC50=4.29 ?M), Saccharomyces cerevisiae (EC50=5.23 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12543672	Antimicrob Agents Chemother 2003 Feb;47(2):643-652.	"Bobek LA, Situ H."	"MUC7 20-Mer: Investigation of Antimicrobial Activity, Secondary Structure, and Possible Mechanism of Antifungal Action."
DRAMP03590	VAIALKAAHYHTHKE	15	"Calcitermin (Human, mammals, animals)"	"P80511, P83219, Q5SY66"	Belongs to the S-101 family	S100A12	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Alpha helix 	Not found	None	"Function: S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Possesses antifungal activity against C. albicans and is also active against E. coli and P. aeruginosa but not L. monocytogenes and S. aureus.
Tissue specificity: Predominantly expressed by neutrophils, monocytes and activated macrophages. Expressed by eosinophils and macrophages in asthmatic airways in regions where mast cells accumulate. Found in high concentrations in the serum of patients suffering from various inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and Kawasaki disease.
Domain: The hinge Domain: contributes significantly to its chemotactic properties."	"Gram-negative bacteria: Escherichia coli, Pseudomonas aeruginosa.##Yeast: Candida albicans at pH 5.4."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11522286	FEBS Lett. 2001 Aug 24;504(1-2):5-10.	"Cole AM, Kim YH, Tahk S, Hong T, Weis P, Waring AJ, Ganz T."	"Calcitermin, a novel antimicrobial peptide isolated from human airway secretions."
DRAMP03591	ACYCRIPACIAGERRYGTCIYQGRLWAFCC	30	"Neutrophil defensin 1 (Defensin, alpha 1; HNP-1, HP-1; Human, mammals, animals)"	"P59665, P11479, Q14125, Q6EZF6"	Belongs to the alpha-defensin family	"DEFA1, DEFA1B"	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral(SARS-CoV-2)"	Protein level	Beta strand	"Compared to HNP-2, HNP-1 contains one additional residue (Ala) at the N-terminus. It contains a long stretch of a double-stranded antiparallel beta-sheet in a hairpin conformation that contains a beta-bulge, a short region of triple-stranded beta-sheet, and several tight turns."	2KHT resolved by NMR	"Function: Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
PTM: ADP-ribosylation drastically reduces cytotoxic and antibacterial activities, and enhances IL8 production. Phosphorylation at Tyr-85 has been found in some cancer cell lines, and interferes with ADP-rybosylation."	"[Ref.34206990]Virus:SARS-CoV-2:inhibition of infection in HEK293T-hACE2 cells(approximately 50% inbibition at 1 ¦Ìg/mL (290 nM));SARS-CoV-2 variant P.1:inhibition of infection in HeLa-hACE2 cells(67% inbibition at 50 ¦Ìg/mL);SARS-CoV-2 variant B.1.1.7:inhibition of infection in HeLa-hACE2 cells(58% inbibition at 50 ¦Ìg/mL).##[Ref.15616305] Gram-negative bacteria: Escherichia coli ATCC 8739 (vLD50=3.6¡À0.3 ¦Ìg/ml), E. coli ATCC 25922 (vLD50=3.7¡À0.4 ¦Ìg/ml), Enterobacter aerogenes ATCC 13048 (vLD50=10¡À0.5 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (vLD50=4.2¡À1.0 ¦Ìg/ml), Staphylococcus aureus ATCC 29213 (vLD50=2.1¡À0.3 ¦Ìg/ml), Bacillus cereus ATCC 10876 (vLD50=0.22¡À0.03 ¦Ìg/ml).##NOTE: vLD50, virtual lethal doses (vLDs), equivalent to conventional 50% lethal doses (LD50s).##[Ref.15118082]Gram-positive bacteria: Bacillus subtilis (Inhibition zone=24 mm in PH5.5, Inhibition zone=20 mm in PH7.5 completely inhibit at 10 ¦Ìg/well), Staphylococcus aureus  (Inhibition zone=1 mm in PH5.5, Inhibition zone=7 mm incompletely inhibit and Inhibition zone=2 mm completely inhibit in PH7.5 at 10 ¦Ìg/well);##Gram-negative bacteria: Escherichia coli (Inhibition zone=5 mm incompletely inhibit and Inhibition zone=2 mm completely inhibit in PH7.5 at 10 ¦Ìg/well);##Fungi: Candida albicans (Inhibition zone=13 mm in PH5.5, Inhibition zone=10 mm in PH7.5 completely inhibit at 10 ¦Ìg/well)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization(Cys2 and Cys30).	"Disulfide bonds between Cys2 and Cys30,Cys4 and Cys19,Cys9 and Cys29."	L	[Ref.34206990]No cytotoxicity on HEK293T cells up to 50 ¦Ìg/mL.	Not found	34206990##19253295##15616305##15118082	Viruses. 2021 Jun 26;13(7):1246.##Proteomics. 2009 Mar;9(5):1364-1373.##Antimicrob Agents Chemother. 2005 Jan;49(1):269-275.##Proc Natl Acad Sci U S A. 2004 May 11;101(19):7363-8.	"Xu C, Wang A, Marin M, Honnen W, Ramasamy S, Porter E, Subbian S, Pinter A, Melikyan GB, Lu W, Chang TL.##Stegemann C, Kolobov A Jr, Leonova YF, Knappe D, Shamova O, Ovchinnikova TV, Kokryakov VN, Hoffmann R.##Ericksen B, Wu Z, Lu W, Lehrer RI.##Yount NY, Yeaman MR."	"Human Defensins Inhibit SARS-CoV-2 Infection by Blocking Viral Entry.##Isolation, purification and de novo sequencing of TBD-1, the first beta-defensin from leukocytes of reptiles.##Antibacterial activity and specificity of the six human {alpha}-defensins.##Multidimensional signatures in antimicrobial peptides."
DRAMP03592	CYCRIPACIAGERRYGTCIYQGRLWAFCC	29	"Neutrophil defensin 2 (HNP-2, HP-2, HP2; Human, mammals, animals)"	"P59665, P11479, Q14125, Q6EZF6, P59666, P11479, Q14125"	Belongs to the alpha-defensin family	DEFA1 AND DEFA1B	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral(SARS-CoV-2)"	Protein level	Beta strand	Not found	"1ZMH, 1ZMI, 1ZMK resolved by X-ray."	"Function: Defensin 2 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
PTM: Contains three disulfide bonds 1-29; 3-18; 8-28."	"[Ref.34206990]Virus:SARS-CoV-2:inhibition of infection in HEK293T-hACE2 cells(approximately 50% inbibition at 1 ¦Ìg/mL (290 nM)).##Gram-negative bacteria: Escherichia coli ATCC 8739 (vLD50=3.5¡À0.79 ?g/ml), E. coli ATCC 25922 (vLD50=3.5¡À0.6 ?g/ml), Enterobacter aerogenes ATCC 13048 (vLD50=16¡À4.0 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (vLD50=4.2¡À0.9 ?g/ml), S. aureus ATCC 29213 (vLD50=2.4¡À0.3 ?g/ml), Bacillus cereus ATCC 10876 (vLD50=0.22¡À0.04 ?g/ml).(Ref.2)##NOTE: vLD50, virtual lethal doses (vLDs), equivalent to conventional 50% lethal doses (LD50s)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bonds between Cys1 and Cys29,Cys3 and Cys18,Cys8 and Cys28."	L	No cytotoxicity information found in the reference(s) presented	Not found	34206990##15616305##15894545	Viruses. 2021 Jun 26;13(7):1246.##Antimicrob Agents Chemother. 2005 Jan;49(1):269-275.##J Biol Chem. 2005 Sep 23;280(38):32921-9.	"Xu C, Wang A, Marin M, Honnen W, Ramasamy S, Porter E, Subbian S, Pinter A, Melikyan GB, Lu W, Chang TL.##Ericksen B, Wu Z, Lu W, Lehrer RI.##Xie C, Prahl A, Ericksen B, Wu Z, Zeng P, Li X, Lu WY, Lubkowski J, Lu W."	Human Defensins Inhibit SARS-CoV-2 Infection by Blocking Viral Entry.##Antibacterial activity and specificity of the six human {alpha}-defensins.##Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
DRAMP03593	DCYCRIPACIAGERRYGTCIYQGRLWAFCC	30	"Neutrophil defensin 3 (Defensin, alpha 3; HNP-3, HP-3, HP3; Human, mammals, animals)"	"P59666, P11479, Q14125"	Belongs to the alpha-defensin family	DEFA3	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral(SARS-CoV-2)"	Protein level	Beta strand	"Compared to HNP-2, HNP-3 contains one additional residue (Asp) at the N-terminus. The 3D structures remain the same. "	"1DFN, 2PM4, 2PM5 resolved by X-ray."	"Function: Defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
PTM: Contains three disulfide bonds 2-30; 4-19; 9-29."	"[Ref.34206990]Virus:SARS-CoV-2:inhibition of infection in HEK293T-hACE2 cells(approximately 50% inbibition at 1 ¦Ìg/mL (290 nM)).##Gram-negative bacteria: Escherichia coli ATCC 8739 (vLD50=6.2¡À0.9 ?g/ml), E. coli ATCC 25922 (vLD50=5.9¡À2.1 ?g/ml), Enterobacter aerogenes ATCC 13048 (vLD50=41¡À9.2 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (vLD50=13¡À2.1 ?g/ml), S. aureus ATCC 29213 (vLD50=2.2¡À0.4 ?g/ml), Bacillus cereus ATCC 10876 (vLD50=0.37¡À0.08 ?g/ml).(Ref.2)##NOTE: vLD50, virtual lethal doses (vLDs), equivalent to conventional 50% lethal doses (LD50s)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization(Cys2 and Cys30).	"Disulfide bonds between Cys2 and Cys30,Cys4 and Cys19,Cys9 and Cys29."	L	No cytotoxicity information found in the reference(s) presented	Not found	34206990##4056036##15616305	Viruses. 2021 Jun 26;13(7):1246.##J Clin Invest. 1985 Oct;76(4):1436-1439.##Antimicrob Agents Chemother. 2005 Jan;49(1):269-275.	"Xu C, Wang A, Marin M, Honnen W, Ramasamy S, Porter E, Subbian S, Pinter A, Melikyan GB, Lu W, Chang TL.##Selsted ME, Harwig SS, Ganz T, Schilling JW, Lehrer RI.##Ericksen B, Wu Z, Lu W, Lehrer RI."	Human Defensins Inhibit SARS-CoV-2 Infection by Blocking Viral Entry.##Primary structures of three human neutrophil defensins.##Antibacterial activity and specificity of the six human {alpha}-defensins.
DRAMP03594	VCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRV	33	"Neutrophil defensin 4 (Defensin, alpha 4; HNP-4, HP-4; Human, mammals, animals)"	P12838	Belongs to the alpha-defensin family	DEFA4	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral(SARS-CoV-2)"	Protein level	Beta strand	"Compared to HNP-2, HNP-1 contains one additional residue (Ala) at the N-terminus. It contains a long stretch of a double-stranded antiparallel beta-sheet in a hairpin conformation that contains a beta-bulge, a short region of triple-stranded beta-sheet, and several tight turns."	1ZMM resolved by X-ray.	"Function: Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). In comparison with HNP1-3, inhibition of both strains of HIV-1 by HNP4 was noticeably stronger as evidenced by lower IC50 values (2-5 ?M) and steeper and more complete inhibition curves.
PTM: Contains three disulfide bonds 2-30; 4-19; 9-29."	"[Ref.34206990]Virus:showed inhibition against SARS-CoV-2.Gram-negative bacteria: Escherichia coli ATCC 8739 (vLD50=3.3¡À0.4 ?g/ml), E. coli ATCC 25922 (vLD50=3.0¡À0.7 ?g/ml), Enterobacter aerogenes ATCC 13048 (vLD50=6.6¡À0.2 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (vLD50=7.3¡À1.4 ?g/ml), S. aureus ATCC 29213 (vLD50=7.2¡À0.2 ?g/ml), Bacillus cereus ATCC 10876 (vLD50=0.87¡À0.08 ?g/ml).(Ref.4)##NOTE: vLD50, virtual lethal doses (vLDs), equivalent to conventional 50% lethal doses (LD50s).##Yeast: Candida albicans ATCC 99788 amphotericin B resistant (IC90>100 ?g/ml).(Ref.2)"	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys2 and Cys30,Cys4 and Cys19,Cys9 and Cys29."	L	No cytotoxicity information found in the reference(s) presented	Not found	34206990##17088326##15620707##15616305	Viruses. 2021 Jun 26;13(7):1246.##Protein Sci. 2006 Dec;15(12):2749-2760.##FEBS Lett. 2005 Jan 3;579(1):162-166.##Antimicrob Agents Chemother. 2005 Jan;49(1):269-275.	"Xu C, Wang A, Marin M, Honnen W, Ramasamy S, Porter E, Subbian S, Pinter A, Melikyan GB, Lu W, Chang TL.##Szyk A, Wu Z, Tucker K, Yang D, Lu W, Lubkowski J.##Wu Z, Cocchi F, Gentles D, Ericksen B, Lubkowski J, Devico A, Lehrer RI, Lu W.##Ericksen B, Wu Z, Lu W, Lehrer RI."	"Human Defensins Inhibit SARS-CoV-2 Infection by Blocking Viral Entry.##Crystal structures of human alpha-defensins HNP4, HD5, and HD6.##Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro.##Antibacterial activity and specificity of the six human {alpha}-defensins."
DRAMP03595	ATCYCRTGRCATRESLSGVCEISGRLYRLCCR	32	"Human defensin-5 (HD-5; Defensin, alpha 5; Human, mammals, animals)"	"Q01523, A0JDY6, Q3KNV2"	Belongs to the alpha-defensin family	DEFA5	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral(SARS-CoV-2)"	Protein level	Beta strand	The L- and D-forms of HD-5 are equally active than E.coli but not S. aureus (Wei G et al 2009 JBC 284: 29180-92). 	1ZMP resolved by X-ray.	"Function: Antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.
Tissue specificity: Paneth cells of the small intestine (at protein level).
PTM: Contains three disulfide bonds."	"[Ref.34206990]Virus:SARS-CoV-2:inhibition of infection in HEK293T-hACE2 cells(60% inhibition at 12.5 ¦Ìg/mL (3.45 ¦ÌM));SARS-CoV-2 variant P.1:inhibition of infection in HeLa-hACE2 cells(72% inbibition at 50 ¦Ìg/mL);SARS-CoV-2 variant B.1.1.7:inhibition of infection in HeLa-hACE2 cells(32% inbibition at 50 ¦Ìg/mL).##Gram-negative bacteria: Escherichia coli ATCC 8739 (vLD50=2.5¡À0.3 ?g/ml), E. coli ATCC 25922 (vLD50=2.1¡À0.9 ?g/ml), Enterobacter aerogenes ATCC 13048 (vLD50=5.5¡À0.5 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (vLD50=6.3¡À0.5 ?g/ml), S. aureus ATCC 29213 (vLD50=3.2¡À0.3 ?g/ml), Bacillus cereus ATCC 10876 (vLD50<0.31 ?g/ml).(Ref.2)##NOTE: vLD50, virtual lethal doses (vLDs), equivalent to conventional 50% lethal doses (LD50s)."	[Ref.26206286] It has 0% hemolysis at 100¦ÌM against human red blood cells.	Cyclic	Free	Free	"Disulfide bonds between Cys3 and Cys31,Cys5 and Cys20,Cys10 and Cys30."	L	[Ref.34206990]No cytotoxicity on HEK293T cells up to 50 ¦Ìg/mL.	Not found	34206990##12021776##15616305##26206286	Viruses. 2021 Jun 26;13(7):1246.##Nat Immunol. 2002 Jun;3(6):583-590.##Antimicrob Agents Chemother. 2005 Jan;49(1):269-275.##Peptides. 2015 Sep;71:128-40. doi: 10.1016/j.peptides.2015.07.009. Epub 2015 Jul 20.	"Xu C, Wang A, Marin M, Honnen W, Ramasamy S, Porter E, Subbian S, Pinter A, Melikyan GB, Lu W, Chang TL.##Ghosh D, Porter E, Shen B, Lee SK, Wilk D, Drazba J, Yadav SP, Crabb JW, Ganz T, Bevins CL.##Ericksen B, Wu Z, Lu W, Lehrer RI.##Basil Mathew Ramakrishnan Nagaraj"	Human Defensins Inhibit SARS-CoV-2 Infection by Blocking Viral Entry.##Paneth cell trypsin is the processing enzyme for human defensin-5.##Antibacterial activity and specificity of the six human {alpha}-defensins.##Antimicrobial activity of human  -defensin 5 and its linear analogs: N-terminal fatty acylation results in enhanced antimicrobial activity of the linear analogs
DRAMP03596	AFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL	32	"Human defensin-6 (HD-6; Defensin, alpha 6; Human, mammals, animals)"	Q01524	Belongs to the alpha-defensin family	DEFA6	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral(SARS-CoV-2)"	Protein level	Beta strand (3 strands; 19 residues)	Not found	"1ZMQ, 3QTE resolved by X-ray."	"Function: Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1.
Subunit structure: Homodimer.
Tissue specificity: Paneth cells of the small intestine.
PTM: Contains three disulfide bonds."	"[Ref.34206990]Virus:SARS-CoV-2:inhibition of infection in HEK293T-hACE2 cells(HD6 only blocked SARS-CoV-2 infection at the highest concentration tested (50 ¦Ìg/mL, 13 ¦ÌM)).##Gram-negative bacteria: Escherichia coli ATCC 8739 (vLD50>256 ?g/ml), E. coli ATCC 25922 (vLD50=103¡À14 ?g/ml), Enterobacter aerogenes ATCC 13048 (vLD50=156¡À11 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (vLD50>256 ?g/ml), S. aureus ATCC 29213 (vLD50>256 ?g/ml), Bacillus cereus ATCC 10876 (vLD50=25¡À13 ?g/ml).(Ref.3)##NOTE: vLD50, virtual lethal doses (vLDs), equivalent to conventional 50% lethal doses (LD50s)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys4 and Cys31,Cys6 and Cys20,Cys10 and Cys30."	L	[Ref.34206990]No cytotoxicity on HEK293T cells up to 50 ¦Ìg/mL.	Not found	34206990##8417977##17088326##15616305	Viruses. 2021 Jun 26;13(7):1246.##FEBS Lett. 1993; 315:187-192.##Protein Sci. 2006 Dec;15(12):2749-2760.##Antimicrob Agents Chemother. 2005 Jan;49(1):269-275.	"Xu C, Wang A, Marin M, Honnen W, Ramasamy S, Porter E, Subbian S, Pinter A, Melikyan GB, Lu W, Chang TL.##Jones DE, Bevins CL.##Szyk A, Wu Z, Tucker K, Yang D, Lu W, Lubkowski J.##Ericksen B, Wu Z, Lu W, Lehrer RI."	"Human Defensins Inhibit SARS-CoV-2 Infection by Blocking Viral Entry.##Defensin-6 mRNA in human Paneth cells: implications for antimicrobial peptides in host defense of the human bowel.##Crystal structures of human alpha-defensins HNP4, HD5, and HD6.##Antibacterial activity and specificity of the six human {alpha}-defensins."
DRAMP18203	SYVGDCGSNGGSCVSSYCPYGNRLNYFCPLGRTCCRRSY	39	"Panusin (beta defensins; crustaceans, arthropods, invertebrates, animals)"	A0A0S2XGP2(Precursor)	Belongs to the beta-defensin family	Not found	"the Caribbean spiny lobster, Panulirus genus"	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"		Not found	Not found	None	"Function: Active against E. coli, K. pneumonia, S. aureus, B. subtilisspizizenii, and C. albicans."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Lipid-binding	27616720	Dev Comp Immunol. pii: S0145-305X(16)30274-9(2016)	"Montero-Alejo V, Corzo G, Porro-Suard"	Panusin represents a new family of beta-defensin-like peptides in invertebrates.
DRAMP18120	PPTQNPSMAPPTQNPYGQPMTPPTQNPYGQPMAPP	35	BnPRP1 (Plant defensin)	No entry found		BnPRP1	Brassica napus	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"		Not found	Not found	None	"BnPRP1 has 40.5% identity with a known proline-rich antimicrobial peptide SP-B from the pig. BnPRP1 isolated from B. napus was the first PR-AMP member that was characterized in plants, and its homology sequences were found in some other Brassicaceae plants by the genome sequences analysis. "	"Gram-positive: M. luteus (MIC= 16.9 ¡À 2.7 uM );##Gram-negative: E. coli (MIC= 8.4 ¡À 1.4 uM);## Fungi:Sclerotinia sclerotiorum, Mucor sp., Magnaporthe oryzae and Botrytis cinerea"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	26383098	PLoS One.?2015 Sep 18;10(9):e0137414.	"Cao H, Ke T, Liu R, et al."	Identification of a Novel Proline-Rich Antimicrobial Peptide from Brassica napus.
DRAMP18140	VARGWKRKCPLFGKGG	16	VG16KRKP	No entry found			Synthetic construct	"Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-"	Synthetic		The solution-NMR structure of VG16KRKP in lipopolysaccharide features a folded conformation with a centrally located turn-type structure stabilized by aromatic-aromatic packing interactions with extended N- and C-termini.	"2MXG,2MXH resolved by NMR"	VG16KRKP is capable of inhibiting bacterial disease progression in plants.	"Gram-negative: E. coli (MIC=8 uM), X. campestris  (MIC=10 uM), X. oryzae  (MIC=15 uM);##Gram-positive: B. subtilis (MIC=50 uM);##Fungi: Candida albicans  (MIC=2 uM), Cryptococcus grubii  (MIC=5 uM)"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	cell membrane	26144972	Sci Rep. 2015 Jul 6;5:11951.	"Datta A, Ghosh A, Airoldi C, etal."	"Antimicrobial Peptides: Insights into Membrane Permeabilization, Lipopolysaccharide Fragmentation and Application in Plant Disease Control"
DRAMP03633	MLTELEKALNSIIDVYHKYSLIKGNFHAVYRDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEESHKE	93	"Protein S100-A8 (Calgranulin-A; MRP-8; Human, mammals, animals)"	"P05109, A8K5L3, D3DV37, Q5SY70, Q9UC84, Q9UC92, Q9UCJ0, Q9UCM6"	Belongs to the S-100 family	S100A8	Homo sapiens (Human)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Combine helix and strand structure	The dimeric form of MRP8 is stabilized by hydrophobic interactions between mutually wrapped helices. There are two EF-hand motifs per monomer and each EF-hand bound one Ca(2+) with a different affinity [the affinity of the C-terminal EF-hand (EF-2) for Ca(2+) is stronger than that of the N-terminal EF-hand (EF-1)]. 	1MR8 resolved by X-ray.	"Function: Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn2+ which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect.
Tissue specificity: Calprotectin (S100A8/9) is predominantly expressed in myeloid cells.
Miscellaneous: Binds two calcium ions per molecule with an affinity similar to that of the S100 proteins (By similarity)."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Metal-binding	3313057##10771424	Nature. 1987 Nov 5-11;330(6143):80-82.##Acta Crystallogr D Biol Crystallogr. 2000 May;56(Pt 5):559-566.	"Odink K, Cerletti N, Br¨¹ggen J, Clerc RG, Tarcsay L, Zwadlo G, Gerhards G, Schlegel R, Sorg C.##Ishikawa K, Nakagawa A, Tanaka I, Suzuki M, Nishihira J."	"Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis.##The structure of human MRP8, a member of the S100 calcium-binding protein family, by MAD phasing at 1.9 A resolution."
DRAMP03637	ATFNFINNCPFTVWAAAVPG	20	Thaumatin-like protein (Actc2)	P83958	Belongs to the thaumatin family	tlp	Actinidia chinensis (Kiwi) (Yangtao)	"Antimicrobial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	Function: Has antifungal activity. Inhibits HIV-1 reverse transcriptase.	"Botrytis cinerea, Coprinus comatus, Mycosphaerella arachidicola, Physalospora piricola, Candida albicans, Saccharomyces carlsbergensis, HIV-1 reverse transcriptase."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12165295##12417892##15536427	Phytochemistry. 2002 Sep;61(1):1-6.##J Allergy Clin Immunol. 2002 Nov;110(5):805-810.##J Allergy Clin Immunol. 2004 Nov;114(5):1169-1175.	"Wang H, Ng TB.##Gavrovi?-Jankulovi? M, ?Irkovi? T, Vuckovi? O, Atanaskovi?-Markovi? M, Petersen A, Gojgi? G, Burazer L, Jankov RM.##Bublin M, Mari A, Ebner C, Knulst A, Scheiner O, Hoffmann-Sommergruber K, Breiteneder H, Radauer C."	Isolation of an antifungal thaumatin-like protein from kiwi fruits.##Isolation and biochemical characterization of a thaumatin-like kiwi allergen.##IgE sensitization profiles toward green and gold kiwifruits differ among patients allergic to kiwifruit from 3 European countries.
DRAMP03640	DSHEKRHHEHRRKFHEKHHSHRGY	24	Hcl-hst 5 (N.leucogenys histatin 5)	No entry found	Not found	Not found	Nomascus leucogenys	"Antimicrobial, Antifungal"	Not found	Alpha helix (CD)	Not found	None	Rich in histidines. Partial helical in 50% TFE.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20423320	Protein Pept Lett. 2010 Jul;17(7):909-918.	"Padovan L, Segat L, Pontillo A, Antcheva N, Tossi A, Crovella S."	Histatins In Non-Human Primates: Gene Variations and Functional Effects.
DRAMP03641	DFGCGQGMIFMCQRRCMRLYPGSTGFCRGFRCMCDTHIPLRPPFMVG	47	"Longicornsin (defensin-like; Arthropods, invertebrates, animals)"	B2MW54	Not found	sGDLP	Haemaphysalis longicornis	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has antibacterial activity.	"Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacteria: Escherichia coli, Pseudomonas aeruginosa, Helicobacter pylori.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20027626	Protein Sci. 2010 Mar;19(3):392-327.	"Lu X, Che Q, Lv Y, Wang M, Lu Z, Feng F, Liu J, Yu H."	"A novel defensin-like peptide from salivary glands of the hard tick, Haemaphysalis longicorn."
DRAMP03648	GRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIWG	40	"Gallinacin-1 (Gal-1; Beta-defensin 1; Birds, animals)"	"P46156, Q09MK1, Q6B9W7, Q6GXJ4"	Belongs to the beta-defensin family	GAL1	Gallus gallus (Chicken)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge 	Not found	None	"Tissue specificity: Strong expression in the bone marrow, lung, testis. Moderate expression in the bursa and intestine. Low expression in the cloaca, gall bladder, brain and pancreas. Expressed in the vagina, ovarian stroma and the theca and granulosa layers of the ovarian follicle.
Developmental stage: Detected in the theca layer of the ovarian follicle in the white follicle (WF) stage, but decreases throughout the F1, F3, F5, and postovulatory follicle stages. Detected in the granulosa layer of the ovarian follicle in the white follicle (WF) stage, F1, F3, F5, and postovulatory follicle stages. In the vagina expression is higher in laying hens than in non-laying hens, and is higher in older laying hens than in young laying hens.
Induction: Induced in the theca layer of the F3 stage ovarian follicle by intravenous injection of LPS. Repressed in the granulosa layer of the F3 stage ovarian follicle by intravenous injection of LPS. Expression in cultured vaginal cells is increased by LPS and S.enteritidis. Expression in the kidney and liver is not affected by intravenous injection of LPS.
PTM: Contains three disulfide bonds 6-34; 13-28; 18-35."	Gram-negative bacterium: Escherichia coli ML-35;##Gram-positive bacterium: Listeria monocytogenes.##Yeast: Candida albicans.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8150085##16394622##17244739	FEBS Lett. 1994 Apr 11;342(3):281-285.##J Reprod Dev. 2006 Apr;52(2):211-218.##Reproduction. 2007 Jan;133(1):127-133.	"Harwig SS, Swiderek KM, Kokryakov VN, Tan L, Lee TD, Panyutich EA, Aleshina GM, Shamova OV, Lehrer RI.##Yoshimura Y, Ohashi H, Subedi K, Nishibori M, Isobe N.##Subedi K, Isobe N, Nishibori M, Yoshimura Y."	"Gallinacins: cysteine-rich antimicrobial peptides of chicken leukocytes.##Effects of age, egg-laying activity, and Salmonella-inoculation on the expressions of gallinacin mRNA in the vagina of the hen oviduct.##Changes in the expression of gallinacins, antimicrobial peptides, in ovarian follicles during follicular growth and in response to lipopolysaccharide in laying hens (Gallus domesticus)."
DRAMP03649	GRKSDCFRKNGFCAFLKCPYLTLISGKCSRFHLCCKRIW	39	"Gallinacin-1 alpha (Gal-1 alpha; Antimicrobial peptide CHP2; Birds, animals)"	"P46157, P80390, Q09MR8, Q9DG59"	Belongs to the beta-defensin family	Not found	Gallus gallus (Chicken)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	PTM: Contains three disulfide bonds 6-34; 13-28; 18-35.	"Gram-negative bacterium: Escherichia coli ML-35;##Gram-positive bacteria: Staphylococcus aureus, Listeria monocytogenes.##Yeast: Candida albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7964174##8150085	J Leukoc Biol. 1994 Nov;56(5):661-665.##FEBS Lett. 1994 Apr 11;342(3):281-285.	"Evans EW, Beach GG, Wunderlich J, Harmon BG.##Harwig SS, Swiderek KM, Kokryakov VN, Tan L, Lee TD, Panyutich EA, Aleshina GM, Shamova OV, Lehrer RI."	Isolation of antimicrobial peptides from avian heterophils.##Gallinacins: cysteine-rich antimicrobial peptides of chicken leukocytes.
DRAMP03668	YLDVKQLANYLLCIGNGQVFNGRKTCQIGCRAVCQQPGCSGYKECEQIPNIRLHKYRCHCNEA	63	Megourin-1 (arthropod; animals)	P83417	Not found	Not found	Megoura viciae (Vetch aphid)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacteria and fungi.
Induction: By bacterial infection.
PTM: Contains four disulfide bonds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUL-2002) to UniProtKB	"Bulet P, Charlet M, Chernish S, Hetru C."	Unknown
DRAMP03669	YLDVNQIASYLLCLGQGAVFNGRKTCQIGCRAACQQPGCGGYKECEQIPNIRLHKYRCHCNSG	63	Megourin-2 (arthropod; animals)	P83418	Not found	Not found	Megoura viciae (Vetch aphid)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacteria and fungi.
Induction: By bacterial infection.
PTM: Contains four disulfide bonds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUL-2002) to UniProtKB	"Bulet P, Charlet M, Chernish S, Hetru C."	Unknown
DRAMP03670	YLDVNQIASYLLCLGEGAVFNGRKTCQIGCRAACQQPGCGGYKECEQIPNIRLHKYRCHCISG	63	Megourin-3 (arthropod; animals)	P83419	Not found	Not found	Megoura viciae (Vetch aphid)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	"Function: Has antimicrobial activity against Gram-positive bacteria and fungi.
Induction: By bacterial infection.
PTM: Contains four disulfide bonds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUL-2002) to UniProtKB	"Bulet P, Charlet M, Chernish S, Hetru C."	Unknown
DRAMP03672	VHVGPCDQVCSRIDPEKDECCRAHGYRGHSSCYYGRMECY	40	"Spodomicin (Insects, animals)"	P83411	Belongs to the diapausin family	Not found	Spodoptera littoralis 	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Fungicide.
Tissue specificity: Hemolymph.
Induction: By bacterial infection.
PTM: Contains three disulfide bonds."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUL-2003) to UniProtKB	"Bulet P, Lamberty M, Brookhart G, Bushey D."	Unknown
DRAMP18192	FLFSLIPNAISGLLSAFK	18	Antimicrobial peptide AcrAP2	A0A0A1I6N9	 Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short an	Not found	Androctonus crassicauda (Arabian fat-tailed scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Has antimicrobial activity against the Gram-positive bacteria S.aureus and the yeast C.albicans. Causes hemolysis on horse erythrocytes (64 uM for 100% hemolysis).	"Gram-positive bacteria: S.aureus (MIC=8 uM, MBC=32 uM);##Yeast: C.albicans (MIC=16 uM)"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	25332684	Int. J. Biol. Sci. 10:1097-1107(2014)	"Du Q., Hou X., Ge L., Li R., Zhou M., Wang H., Wang L., Wei M.,Chen T., Shaw C."	"Cationicity-enhanced analogues of the antimicrobial peptides, AcrAP1and AcrAP2, from the venom of the scorpion, Androctonus crassicauda,display potent growth modulation effects on human cancer cell lines."
DRAMP03695	GFWSKIKDFAKKAWNSPLANELKSKALNAAKNFVSEKIGATPS	43	"Probable antimicrobial peptide Con13 (Arthropods, animals)"	C7C1L2	Belongs to the antimicrobial peptide scorpion family	Not found	Opisthacanthus cayaporum (South American scorpion)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Hemolytic and antibacterial and antifungal peptide (By similarity).
Tissue specificity: Expressed by the venom gland."	No MICs found in DRAMP database	[Swiss_Prot Entry C7C1L2]has hemolytic activity	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	cell membrane	19379768	Toxicon. 2009 Sep 1;54(3):252-261.	"Silva EC, Camargos TS, Maranh?o AQ, Silva-Pereira I, Silva LP, Possani LD, Schwartz EF."	Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum.
DRAMP18417	FFGTLFKLGSKLIPGVMKLFSKKKER	26	ToAP2	A0A1D3IXJ5	Derived from NDBP subfamily 3	Not found	Tityus obscurus	"Antimicrobial, Antifungal, Antibiofilm"	Transcript level	Alpha helix	The peptide adopts a structure with 57.69% alpha helix	None	Function: antifungal activity. Has hemolytic activity.	[Ref.27917162] Fungi:Candida albicans (SC5314)(MIC=12.5¦ÌM);Candida tropicalis (ATCC 750)(MIC=3.12¦ÌM);Candida parapsilosis (ATCC 22019)(MIC=50¦ÌM);Candida glabrata (ATCC 90030)(MIC=200¦ÌM);Candida neoformans (H99 serotype A)(MIC=12.5¦ÌM)	"[Ref.27917162] 30% hemolysis at 1.58 ¦ÌM, 37% hemolysis at 3.16 ¦ÌM, 45% hemolysis at 6.31 ¦ÌM, 46% hemolysis at 12.59 ¦ÌM, 48% hemolysis at 25.12 ¦ÌM, 47% hemolysis at 50.11 ¦ÌM , 50% hemolysis at 100¦ÌM against human red blood cell"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27917162	Front Microbiol. 2016 Nov 18;7:1844. eCollection 2016.	"Guilhelmelli F, Vilela N, Smidt KS, de Oliveira MA, da Cunha Morales ?lvares A, Rigonatto MC, da Silva Costa PH, Tavares AH, de Freitas SM, Nicola AM, Franco OL, Derengowski LD, Schwartz EF, Mortari MR, Bocca AL, Albuquerque P, Silva-Pereira I."	Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms.
DRAMP03728	GILREKYAHKAIDVLTPMIGVPVVSKIVNNAAKQLVHKIAKNQQLCMFNKDVAGWCEKSCQQSAHQKGYCHGTKCKCGIPLNYK	84	"Hg-scorpine-like 2 (Arthropods, animals)"	P0C8W5	Belongs to the long chain scorpion toxin family (Class 3 subfamily)	Not found	Hadrurus gertschi (Scorpion)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antimicrobial activity against yeasts and bacteria (By similarity).
Tissue specificity: Expressed by the venom gland.
PTM: Contains three disulfide bonds (By similarity)."	Yeasts	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17506894	BMC Genomics. 2007 May 16;8:119.	"Schwartz EF, Diego-Garcia E, Rodr??guez de la Vega RC, Possani LD."	Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones).
DRAMP03730	KWLNEKSIQNKIDEKIGKNFLGGMAKAVVHKLAKNEFMCMANMDPTGSCETHCQKASGEKGYCHGTKCKCGVPLSY	76	"Opiscorpine-2 (Arthropods, animals)"	"Q5WR01, Q5WR02"	Belongs to the long chain scorpion toxin family (Class 3 subfamily)	Not found	Opistophthalmus carinatus (African yellow leg scorpion)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antimicrobial activity against yeasts and bacteria (By similarity).
Tissue specificity: Expressed by the venom gland.
PTM: Contains three disulfide bonds (By similarity)."	Yeasts	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15241551	Cell Mol Life Sci. 2004 Jul;61(14):1751-1763.	"Zhu S, Tytgat J."	"The scorpine family of defensins: gene structure, alternative polyadenylation and fold recognition."
DRAMP03731	KWLNEKSIQNKIDEKIGKNFLGGMAKAVVHKLAKNEFMCVANVDMTKSCDTHCQKASGEKGYCHGTKCKCGVPLSY	76	"Opiscorpine-3 (Arthropods, animals)"	Q5WQZ7	Belongs to the long chain scorpion toxin family (Class 3 subfamily)	Not found	Opistophthalmus carinatus (African yellow leg scorpion)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antimicrobial activity against yeasts and bacteria (By similarity).
Tissue specificity: Expressed by the venom gland.
PTM: Contains three disulfide bonds (By similarity)."	Yeasts	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15241551	Cell Mol Life Sci. 2004 Jul;61(14):1751-1763.	"Zhu S, Tytgat J."	"The scorpine family of defensins: gene structure, alternative polyadenylation and fold recognition."
DRAMP03732	KWLNEKSIQNKIDEKIGKNFLGGMAKAVVHKLAKNEFMCVANIDMTKSCDTHCQKASGEKGYCHGTKCKCGVPLSY	76	"Opiscorpine-4 (Arthropods, animals)"	Q5WQZ9	Belongs to the long chain scorpion toxin family (Class 3 subfamily)	Not found	Opistophthalmus carinatus (African yellow leg scorpion)	"Antimicrobial, Antibacterial, Antifungal"	Transcript level	Not found	Not found	None	"Function: Has antimicrobial activity against yeasts and bacteria (By similarity).
Tissue specificity: Expressed by the venom gland.
PTM: Contains three disulfide bonds (By similarity)."	Yeasts	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15241551	Cell Mol Life Sci. 2004 Jul;61(14):1751-1763.	"Zhu S, Tytgat J."	"The scorpine family of defensins: gene structure, alternative polyadenylation and fold recognition."
DRAMP03736	GKVWDWIKSTAKKLWNSEPVKELKNTALNAAKNFVAEKIGATPS	44	"Opistoporin-2 (OP2; Non-disulfide-bridged peptide 3.6, NDBP-3.6; Arthropods, animals)"	P83314	Belongs to the antimicrobial peptide scorpion family	Not found	Opistophthalmus carinatus (African yellow leg scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	"Function: At high concentrations, acts as pore former in cellular membranes and causes the leakage of the cells. At submicromolar concentrations, degranulates granulocytes and has weak hemolytic activity against human red blood cells. Also strongly inhibits the production of superoxide anions. Has a strong antibacterial activity against Gram-negative bacteria but is less active against Gram-positive bacteria. Also has antifungal activity. (By similarity)
Tissue specificity: Expressed by the venom gland."	[Swiss_Prot Entry P83314]strong antibacterial activity against Gram-negative bacteria but is less active against Gram-positive bacteria. Also has antifungal activity.	[Swiss_Prot Entry P83314]Weak hemolytic activity against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	12354111	Eur J Biochem. 2002 Oct;269(19):4799-4810.	"Moerman L, Bosteels S, Noppe W, Willems J, Clynen E, Schoofs L, Thevissen K, Tytgat J, Van Eldere J, Van Der Walt J, Verdonck F."	"Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa."
DRAMP03737	GKVWDWIKKTAKDVLNSDVAKQLKNKALNAAKNFVAEKIGATPS	44	"Opistoporin-4 (Non-disulfide-bridged peptides 3.7, NDBP-3.7; Arthropods, animals)"	Q5VJS9	Belongs to the antimicrobial peptide scorpion family	Not found	Opistophthalmus carinatus (African yellow leg scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: At high concentrations, acts as pore former in cellular membranes and causes the leakage of the cells. At submicromolar concentrations, degranulates granulocytes and has weak hemolytic activity against human red blood cells. Also strongly inhibits the production of superoxide anions. Has a strong antibacterial activity against Gram-negative bacteria but is less active against Gram-positive bacteria. Also has antifungal activity. (By similarity)
Tissue specificity: Expressed by the venom gland."	[Swiss_Prot Entry Q5VJS9]strong antibacterial activity against Gram-negative bacteria but is less active against Gram-positive bacteria. Also has antifungal activity.	[Swiss_Prot Entry Q5VJS9]Weak hemolytic activity against human erythrocytes	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	PubMed ID is not available	Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases	"Zhu S, Tytgat J."	Precursor organization and gene structure of scorpion venom antimicrobial peptides.
DRAMP03741	IFGSLFSLGSKLLPSVFKLFSRKKQ	25	"Ponericin-W-like 32.1 (Arthropods, animals)"	P0CI91	Belongs to the ponericin-W family	Not found	Lychas mucronatus (Chinese swimming scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Insecticidal"	Transcript level	Not found	Not found	None	"Function: Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae. Has insecticidal and hemolytic activities (By similarity).
Tissue specificity: Expressed by the venom gland."	[Swiss_Prot Entry P0CI91]Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae	[Swiss_Prot Entry P0CI91]has hemolytic activities	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20663230	BMC Genomics. 2010 Jul 28;11:452.	"Ruiming Z, Yibao M, Yawen H, Zhiyong D, Yingliang W, Zhijian C, Wenxin L."	Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components.
DRAMP03742	IFGSLFSLGSKLLPTVFKLFSRKKQ	25	"Ponericin-W-like 32.2 (Arthropods, animals)"	P0CI92	Belongs to the ponericin-W family	Not found	Lychas mucronatus (Chinese swimming scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Insecticidal"	Transcript level	Not found	Not found	None	"Function: Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae. Has insecticidal and hemolytic activities (By similarity).
Tissue specificity: Expressed by the venom gland."	[Swiss_Prot Entry P0CI92]Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S.cerevisiae	[Swiss_Prot Entry P0CI92]has hemolytic activities	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	20663230	BMC Genomics. 2010 Jul 28;11:452.	"Ruiming Z, Yibao M, Yawen H, Zhiyong D, Yingliang W, Zhijian C, Wenxin L."	Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components.
DRAMP03755	QFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS	37	"Potassium channel toxin alpha-KTx 1.1 (ChTX-Lq1; charybdotoxin; Arthropods, animals)"	P13487	Not found	Not found	Leiurus quinquestriatus hebraeus (Yellow scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral"	Protein level	Combine helix and strand structure	These structures show that charybdotoxin is composed of a beta-sheet linked to an alpha-helix by two disulphide bridges and to an extended fragment by the third disulphide bridge. 	"1BAH, 2CRD resolved by NMR."	"Function: Potent selective inhibitor of high conductance (maxi-K), different medium and small conductance calcium-activated potassium channels (KCa/KCNM), as well as a voltage-dependent potassium channel (Kv1.3/KCNA3). It appears to block channel activity by a simple bimolecular inhibition process.
Tissue specificity: Expressed by the venom gland.
Domain: Has the structural arrangement of an alpha-helix connected to a beta-sheet by disulfide bonds (CSalpha/beta).
PTM: Contains three disulfide bonds."	"Gram-positive bacteria: B.subtilis, S.aureus;##Gram-negative bacterium: E.coli.##Yeast: Candida albicans. "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15118082##1705886##9092804##1380828	Proc Natl Acad Sci U S A. 2004 May 11;101(19):7363-7368.##Eur J Biochem. 1991 Feb 26;196(1):19-28.##Biochemistry. 1997 Apr 1;36(13):3760-3766.##Biochemistry. 1992 Sep 1;31(34):7756-7764.	"Yount NY, Yeaman MR.##Bontems F, Roumestand C, Boyot P, Gilquin B, Doljansky Y, Menez A, Toma F.##Song J, Gilquin B, Jamin N, Drakopoulou E, Guenneugues M, Dauplais M, Vita C, M¨¦nez A.##Bontems F, Gilquin B, Roumestand C, M¨¦nez A, Toma F."	Multidimensional signatures in antimicrobial peptides.##Three-dimensional structure of natural charybdotoxin in aqueous solution by 1H-NMR. Charybdotoxin possesses a structural motif found in other scorpion toxins.##NMR solution structure of a two-disulfide derivative of charybdotoxin: structural evidence for conservation of scorpion toxin alpha/beta motif and its hydrophobic side chain packing.##Analysis of side-chain organization on a refined model of charybdotoxin: structural and functional i
DRAMP18191	FLFSLIPHAISGLISAFK	18	Antimicrobial peptide AcrAP1	A0A0A1I6E7	 Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short an	Not found	Androctonus crassicauda (Arabian fat-tailed scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	Has antimicrobial activity against the Gram-positive bacteria S.aureus and the yeast C.albicans. Causes hemolysis on horse erythrocytes (64 uM for 100% hemolysis).	"Gram-positive bacteria: S.aureus (MIC=8 uM, MBC=32 uM);##Yeast: C.albicans (MIC=16 uM)"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	25332684	Int. J. Biol. Sci. 10:1097-1107(2014)	"Du Q., Hou X., Ge L., Li R., Zhou M., Wang H., Wang L., Wei M.,Chen T., Shaw C."	"Cationicity-enhanced analogues of the antimicrobial peptides, AcrAP1and AcrAP2, from the venom of the scorpion, Androctonus crassicauda,display potent growth modulation effects on human cancer cell lines."
DRAMP03778	ANDPQCLYGNVAAKF	15	Agrocybin (Fungus)	P84797	Not found	Not found	Agrocybe cylindracea (Toadstool)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Protein level	Not found	Not found	None	Function: Has mitogenic activity towards murine splenocytes. Lacks antiproliferative activity towards HepG2 hepatoma cells. 	"Mycosphaerella arachidicola (IC50=125 ?M), HIV-1 reverse transcriptase (IC50=60 ?M), Pseudomonas fluorescens."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15629530	Peptides. 2005 Feb;26(2):191-196.	"Ngai PH, Zhao Z, Ng TB."	"Agrocybin, an antifungal peptide from the edible mushroom Agrocybe cylindracea."
DRAMP03779	XTYNGKCYKKDNICKYKAQSGKTAICKCYVKKCPRDGAKCEFDSYKGKCYC	51	Antifungal protein (AFP; Fungi)	P17737	Not found	afp	Aspergillus giganteus	"Antimicrobial, Antifungal"	Protein level	Beta strand (6 strands; 15 residues)	"The folding of AFP consists of five antiparallel beta strands connected in a -1, -1, +3, +1 topology and highly twisted, defining a small and compact beta barrel stabilized by four internal disulfide bridges. A cationic site formed by up to three lysine side chains adjacent to a hydrophobic stretch, both at the protein surface, may constitute a potential binding site for phospholipids which would be the basis of its biological function."	1AFP resolved by NMR.	"Function: This protein inhibits the growth of a variety of fungal species.
PTM: Contains four disulfide bonds 7-33; 14-40; 26-28; 49-51."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Phospholipids	2226447##7893713	Eur J Biochem. 1990 Oct 5;193(1):31-38.##Biochemistry. 1995 Mar 7;34(9):3009-3021.	"Nakaya K, Omata K, Okahashi I, Nakamura Y, Kolekenbrock H, Ulbrich N.##Campos-Olivas R, Bruix M, Santoro J, Lacadena J, Martinez del Pozo A, Gavilanes JG, Rico M."	Amino acid sequence and disulfide bridges of an antifungal protein isolated from Aspergillus giganteus.##NMR solution structure of the antifungal protein from Aspergillus giganteus: evidence for cysteine pairing isomerism.
DRAMP03783	QWGYGGMPYGGYGGMGGYGMGGYGMGYRRRMWGSPYGGYGGYGGYGGWG	49	"Neuropeptide-like protein 27 (NLP-27; Gly-rich, Tyr-rich; nematodes, animals; Predicted)"	No entry found	Not found	Not found	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15048112	Nat Immunol. 2004 May;5(5):488-494.	"Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03784	QWGYGGYGRGYGGYGGYGRGMYGGYGRGMYGGYGRGMYGGWGK	43	"Neuropeptide-like protein 28 (NLP-28; Gly-rich, Tyr-rich; nematodes, animals; Predicted)"	No entry found	Not found	Not found	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15048112	Nat Immunol. 2004 May;5(5):488-494.	"Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03785	QWGYGGYGRGYGGYGGYGRGMYGGYGRGMYGGYGRGMYGGYGRGMYGGWGK	51	"Neuropeptide-like protein 29 (NLP-29; nematodes, animals)"	O44664	Not found	nlp-29	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: Antimicrobial peptides that have antibacterial and antifungal activity.
Tissue specificity: Weakly or not expressed in absence of infection. Upon infection by D. coniospora, it is expressed in hypoderm. Also expressed in perivulval cells when D. coniospora spores adhere to this region.
Induction: Upon D. coniospora and S. marcescens infection.
PTM: C-terminal amidation."	Gram-negative bacterium: S. marcescens.##Fungi: D. coniospora.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11717458##15048112	Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):14000-14005.##Nat Immunol. 2004 May;5(5):488-494.	"Nathoo AN, Moeller RA, Westlund BA, Hart AC.##Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"Identification of neuropeptide-like protein gene families in Caenorhabditiselegans and other species.##TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03786	QWGYGGYGRGYGGYGGYGRGYGGYGRGYGGYGRGMWGRPYGGYGWGK	47	"Neuropeptide-like protein 30 (NLP-30; Gly-rich, Tyr-rich; nematodes, animals; Predicted)"	No entry found	Not found	Not found	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15048112	Nat Immunol. 2004 May;5(5):488-494.	"Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03787	NAQWGYGGYGRGYGGYGGYGRGYGGYGGYGRGYGGYGRGMYGGYGRPYGGYGWGK	55	"Neuropeptide-like protein 31 (NLP-31; nematodes, animals)"	O44662	Belongs to the YARP family	nlp-31	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	"Function: Antimicrobial peptide that has antifungal and weak antibacterial activity.
Tissue specificity: Expressed in hypoderm.
Developmental stage: Expressed in precomma stasge embryos.
Induction: Strongly up-regulated upon D. coniospora infection.
PTM: C-terminal amidation."	Gram-positive bacterium: Micrococcus luteus;##Gram-negative bacterium: E.coli.##Fungi: D.coniospora.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11717458##15048112	Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):14000-5.##Nat Immunol. 2004 May;5(5):488-494.	"Nathoo AN, Moeller RA, Westlund BA, Hart AC.##Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"Identification of neuropeptide-like protein gene families in Caenorhabditis elegans and other species.##TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03789	EASCARMDVPVMQRIAQGLCTSSCTAQKCMTGICKKVDSHPTCFCGGCSNANDVSLDTLISQLPHN	66	"ABF-1 (nematodes, animals)"	No entry found	Not found	abf-1	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Antifungal"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11772394	Biochem J. 2002 Jan 15;361(Pt 2):221-230.	"Kato Y, Aizawa T, Hoshino H, Kawano K, Nitta K, Zhang H."	"abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans."
DRAMP03790	DIDFSTCARMDVPILKKAAQGLCITSCSMQNCGTGSCKKRSGRPTCVCYRCANGGGDIPLGALIKRG	67	"ABF-2 (nematodes, animals)"	G5EC68	Not found	abf-2	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	"Gram-positive bacteria: Bacillus subtilis IFO3134 (BC50=0.09 ?M), Kocuria varians MAFF118076 (BC50=0.008 ?M), Staphylococcus aureus ATCC6538P (BC50=0.005 ?M);##Gram-negative bacteria: Agrobacterium tumefaciens MAFF1001 (BC50=0.05 ?M), Bdellovibrio bacteriovorus MAFF106101 (BC50=0.06 ?M), Klebsiella pneumoniae MAFF519002 (BC50=0.9 ?M), Escherichia coli JM109 (BC50>15 ?M).##Fungi: Candida krusei MAFF114085 (BC50=0.3 ?M), Debaryomyces hansenii MAFF113836 (BC50>15 ?M), Kluyveromyces thermotolerans MAFF113848 (BC50=0.3 ?M), Paeonia anomala MAFF113717 (BC50=0.08 ?M), Saccharomyces cerevisiae MAFF113011 (BC50=0.6 ?M), Torulaspora delbrueckiiMAFF113811 (BC50>15 ?M). "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11772394	Biochem J. 2002 Jan 15;361(Pt 2):221-230.	"Kato Y, Aizawa T, Hoshino H, Kawano K, Nitta K, Zhang H."	"abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans."
DRAMP03791	QWGYNSYGYGNYGGYGGYPMYGGYGMNGGYGGGGLLGMFLGKKK	44	"Caenacin-1 (Gly-rich, Tyr-rich; CNC-1; nematode, invertebrate, animals)"	No entry found	Not found	Not found	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15048112	Nat Immunol. 2004 May;5(5):488-494.	"Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03792	QYGYGGYPGMMGGYGGYPGMMGGYGMRPYGMGYGMGMGGMGMYRPGLLGMLMGK	54	"Caenacin-2 (Gly-rich, Tyr-rich; CNC-2, nematode, invertebrate, animals)"	No entry found	Not found	Not found	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15048112	Nat Immunol. 2004 May;5(5):488-494.	"Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03793	QYGYGPMMGGYGPGMMGGYGPGMMGGYGPGMMGGYGPGMMGGYGMSPMYGGYGMYRPGLLGMLLG	65	"Caenacin-3 (Gly-rich, Tyr-rich; CNC-3, nematode, invertebrate, animals)"	No entry found	Not found	Not found	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15048112	Nat Immunol. 2004 May;5(5):488-494.	"Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03794	QWGYGPYGGYGGGYPGMYGGYGMRPYGMYGGYGMGMYRPGLLGMLIGK	48	"Caenacin-4 (Gly-rich, Tyr-rich; CNC-4, nematode, invertebrate, animals)"	No entry found	Not found	Not found	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15048112	Nat Immunol. 2004 May;5(5):488-494.	"Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03795	QWGYNSYGGYNSYGNYGGYGGGYNNGYGVNANLGVGGRGG	40	"Caenacin-5 (Gly-rich, Tyr-rich; CNC-5, nematode, invertebrate, animals)"	No entry found	Not found	Not found	Caenorhabditis elegans	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15048112	Nat Immunol. 2004 May;5(5):488-494.	"Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, Kohara Y, Ewbank JJ."	"TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM."
DRAMP03804	VVCACRRALCLPRERRAGFCRIRGRIHPLCCRR	33	"Corticostatin-3 (Corticostatin III; Macrophage antibiotic peptide MCP-1; lagomorphs, mammals, ani"	P01376	Belongs to the alpha-defensin family	Not found	Oryctolagus cuniculus (Rabbit)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Protein level	Bridge 	Not found	None	"Function: This peptide has antibiotic, anti-fungi and antiviral activity. It also inhibits corticotropin (ACTH) stimulated corticosterone production.
PTM: Contains three disulfide bonds (By similarity)."	herpes simplex virus type I	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	6643497##3988726##1311240	J Immunol. 1989 Aug 15;143(4):1358-1365.##J Biol Chem. 1985 Apr 25;260(8):4579-4584.##Endocrinology. 1992 Mar;130(3):1413-1423.	"Ganz T, Rayner JR, Valore EV, Tumolo A, Talmadge K, Fuller F.##Selsted ME, Brown DM, DeLange RJ, Harwig SS, Lehrer RI.##Zhu Q, Solomon S."	The structure of the Rabbit macrophage defensin genes and their organ-specific expression.##Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils.##Isolation and mode of action of rabbit corticostatic (antiadrenocorticotropin) peptides.
DRAMP03805	VVCACRRALCLPLERRAGFCRIRGRIHPLCCRR	33	"Corticostatin-4 (Corticostatin IV; Macrophage antibiotic peptide MCP-2; lagomorphs, mammals, anim"	P01377	Belongs to the alpha-defensin family	Not found	Oryctolagus cuniculus (Rabbit)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Protein level	Bridge 	Not found	None	"Function: This peptide has antibiotic, anti-fungi and antiviral activity. It also inhibits corticotropin (ACTH) stimulated corticosterone production.
PTM: Problely contains three disulfide bonds 3-31; 5-20; 10-30."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	6643497##3988726##1311240	J Biol Chem. 1983 Dec 10;258(23):14485-14489.##J Biol Chem. 1985 Apr 25;260(8):4579-4584.##Endocrinology. 1992 Mar;130(3):1413-1423.	"Selsted ME, Brown DM, DeLange RJ, Lehrer RI.##Selsted ME, Brown DM, DeLange RJ, Harwig SS, Lehrer RI.##Zhu Q, Solomon S."	"Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of Rabbit lung macrophages.##Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils.##Isolation and mode of action of rabbit corticostatic (antiadrenocorticotrop"
DRAMP03836	DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFLNVNCWCET	44	ETD135 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=1.56 ?g/ml), Candida albicans No.245962 (MIC50=1.56 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=6.25 ?g/ml), Cryptococcus neoformans A (MIC50=6.25 ?g/ml), Fusarium solani FFUS 8591 (MIC50=1.56 ?g/ml), Scedosporium prolificans FSSP 8591 (MIC50=0.2 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03837	DKLIGSCVWGAVNYTSNCRAECKRRGYKGGHCGSFLNVNCWCET	44	ETD179 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=1.56 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03838	DKLIGSCVWGAVNYTSNCRAECKRRGYKGGHCGSFANVNCWCET	44	ETD151 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=3.125 ?g/ml), Candida albicans No.245962 (MIC50=0.4 ?g/ml), Aspergillus fumigatus GASP 4707 (MIC50=6.25 ?g/ml), Cryptococcus neoformans A (MIC50=1.56 ?g/ml), Fusarium solani FFUS 8591 (MIC50=0.4 ?g/ml), Scedosporium prolificans FSSP 8591 (MIC50=0.1 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03839	DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCQT	44	ETD131 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=3.125 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=3.125 ?g/ml), Cryptococcus neoformans A (MIC50=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03840	DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCER	44	ETD130 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=1.56 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03841	NKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCET	44	ETD140 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=3.125 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03842	DKLIGSCVWGAVNYTRNCNAECKRRGYKGGHCGSFANVNCWCET	44	ETD150 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=3.125 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=6.25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03843	DKLIGSCVWGAVNYTSRCNAECKRRGYKGGHCGSFANVNCWCET	44	ETD152 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=3.125 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03844	DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFINVNCWCET	44	ETD132 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=6.25 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=6.25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03845	DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANINCWCET	44	ETD133 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=6.25 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03846	DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFLNINCWCET	44	ETD134 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=1.56 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=3.125 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03847	DKLIGSCVWLAVNYTSNCNAECKRRGYKGGHCGSFLNVNCWCET	44	ETD154 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=6.25 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=12.5 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP18190	FLSTIWNGIKSLL	13	"Pantinin-3 (Non-disulfide-bridged peptide 4.22, NDBP-4.22, Non-disulfide-bridged peptide 5.23, ND"	R4JJN6	 Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short an	Not found	Pandinus imperator (Emperor scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	"Function: Amphipathic peptide that possesses relatively strong activities against Gram-positive bacteria and a fungus, but has very weak antimicrobial activities against Gram-negative bacteria. Also exhibits hemolytic activities against human erythrocytes. Furthermore, this peptide potently inhibits the growth of vancomycin-resistant Enterococcus (VRE) S13, a pathogen that can cause a number of human infections.Forms an alpha-helical membrane channel in the prey."	"[Ref.23624072]Gram-positive bacteria: S.aureus (MIC=16 ¦ÌM), B.magaterium (MIC=6 ¦ÌM), M.luteus (MIC=8 ¦ÌM ), VRE (MIC=4 ¦ÌM), MRSA (MIC=12 ¦ÌM);##Gram-negative bacteria: E.coli (MIC=36 ¦ÌM), P.putida (MIC >87 ¦ÌM), K.oxytoca (MIC=87 ¦ÌM), E.cloacae (MIC >87 ¦ÌM), S.enterica (MIC=84 ¦ÌM);##Fungus: C.tropicalis (MIC=17 ¦ÌM)."	"[Ref.23624072]70% hemolytic activity at 16 ¦ÌM, 100% hemolytic activity at 32 ¦ÌM, 100% hemolytic activity at 64 ¦ÌM against human red blood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	23624072##24184590	Peptides 45:28-34(2013)##Peptides 51:35-45(2014	"Zeng X.C., Zhou L., Shi W., Luo X., Zhang L., Nie Y., Wang J., Wu S.,Cao B., Cao H.##Almaaytah A., Albalas Q."	Three new antimicrobial peptides from the scorpion Pandinusimperator.##Scorpion venom peptides with no disulfide bridges: a review.
DRAMP03849	DKLIGSCVWLAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCET	44	ETD156 (Mutant of ARD1; Heliomicin analogs)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Candida albicans IHEM 8060 (MIC50=3.125 ?g/ml), Aspergillus fumigatus GASP4707 (MIC50=25 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	14978308	Protein Sci. 2004 Mar;13(3):703-713.	"Landon C, Barbault F, Legrain M, Menin L, Guenneugues M, Schott V, Vovelle F, Dimarcq JL."	Lead optimization of antifungal peptides with 3D NMR structures analysis.
DRAMP03913	KWKWKW	6	(KW)3	No entry found	Not found	Not found	Synthetic construct (De novo design)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Fusarium solani, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23203110	Int J Mol Sci. 2012; 13(11): 15042-15053.	"Gopal R, Na H, Seo CH, Park Y."	Antifungal Activity of (KW)n or (RW)n Peptide against Fusarium solani and Fusarium oxysporum.
DRAMP03914	KWKWKWKW	8	(KW)4	No entry found	Not found	Not found	Synthetic construct (De novo design)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Fusarium solani, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23203110	Int J Mol Sci. 2012; 13(11): 15042-15053.	"Gopal R, Na H, Seo CH, Park Y."	Antifungal Activity of (KW)n or (RW)n Peptide against Fusarium solani and Fusarium oxysporum.
DRAMP03915	KWKWKWKWKW	10	(KW)5	No entry found	Not found	Not found	Synthetic construct (De novo design)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Fusarium solani, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23203110	Int J Mol Sci. 2012; 13(11): 15042-15053.	"Gopal R, Na H, Seo CH, Park Y."	Antifungal Activity of (KW)n or (RW)n Peptide against Fusarium solani and Fusarium oxysporum.
DRAMP03916	RWRW	4	(RW)2	No entry found	Not found	Not found	Synthetic construct (De novo design)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Fusarium solani, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23203110	Int J Mol Sci. 2012; 13(11): 15042-15053.	"Gopal R, Na H, Seo CH, Park Y."	Antifungal Activity of (KW)n or (RW)n Peptide against Fusarium solani and Fusarium oxysporum.
DRAMP03917	RWRWRW	6	(RW)3	No entry found	Not found	Not found	Synthetic construct (De novo design)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Fusarium solani, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23203110	Int J Mol Sci. 2012; 13(11): 15042-15053.	"Gopal R, Na H, Seo CH, Park Y."	Antifungal Activity of (KW)n or (RW)n Peptide against Fusarium solani and Fusarium oxysporum.
DRAMP03918	RWRWRWRW	8	(RW)4	No entry found	Not found	Not found	Synthetic construct (De novo design)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Fusarium solani, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23203110	Int J Mol Sci. 2012; 13(11): 15042-15053.	"Gopal R, Na H, Seo CH, Park Y."	Antifungal Activity of (KW)n or (RW)n Peptide against Fusarium solani and Fusarium oxysporum.
DRAMP03919	RWRWRWRWRW	10	(RW)5	No entry found	Not found	Not found	Synthetic construct (De novo design)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Possess antifungal activity.	"Fungi: Fusarium solani, Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23203110	Int J Mol Sci. 2012; 13(11): 15042-15053.	"Gopal R, Na H, Seo CH, Park Y."	Antifungal Activity of (KW)n or (RW)n Peptide against Fusarium solani and Fusarium oxysporum.
DRAMP03940	FPWWWPF	7	Peptide 4 (Trp- and Arg-rich; derivative of Tritrpticin)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Antifungal"	Synthetic	Rich	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8706838	FEBS Lett. 1996 Jul 15;390(1):95-98.	"Lawyer C, Pai S, Watabe M, Borgia P, Mashimo T, Eagleton L, Watabe K."	Antimicrobial activity of a 13 amino acid tryptophan-rich peptide derived from a putative porcine precursor protein of a novel family of antibacterial peptides.
DRAMP03941	RFPWWWPFLR	10	Peptide 3 (Trp- and Arg-rich; derivative of Tritrpticin)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Rich	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Pseudomonas, Klebsiella, Proteus species;##Gram-positive bacteria: Streptococcus, Staphylococcus species. "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8706838	FEBS Lett. 1996 Jul 15;390(1):95-98.	"Lawyer C, Pai S, Watabe M, Borgia P, Mashimo T, Eagleton L, Watabe K."	Antimicrobial activity of a 13 amino acid tryptophan-rich peptide derived from a putative porcine precursor protein of a novel family of antibacterial peptides.
DRAMP03942	RRRFPWVCWPFLRRR	15	Peptide 2 (Trp- and Arg-rich; derivative of Tritrpticin)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Rich	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus mirabilis;##Gram-positive bacteria: Staphylococcus epidermidis, Streptococcus group D.##Fungi: Aspergillus fumigatus."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8706838	FEBS Lett. 1996 Jul 15;390(1):95-98.	"Lawyer C, Pai S, Watabe M, Borgia P, Mashimo T, Eagleton L, Watabe K."	Antimicrobial activity of a 13 amino acid tryptophan-rich peptide derived from a putative porcine precursor protein of a novel family of antibacterial peptides.
DRAMP18396	FFWHHIGHALDAAKRVHGMLSG	22	"moroNC-NH2 (moronecidin-like peptide; fish, animals)"	No entry found	Not found	Not found	Notothenia coriiceps	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against Gram- S. sonnei (ATCC 29930) (MIC 12.5 uM), Psychrobacter sp. (PAMC 25501) (MIC 5 uM), E. coli DH5alpha (MIC 12.5 uM), Gram+ S. pyogenes (ATCC 19615) (MIC 25 uM), S. aureus (ATCC 33591) (MIC 25 uM) , L. monocytogenes (ATCC 15313) (MIC 12.5 uM), and yeast C. tropicalis (ATCC 20115) (MIC 5 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	28122029	PLoS One. 2017 Jan 25;12(1):e0170821.	"Shin SC, Ahn IH, Ahn DH, Lee YM, Lee J, Lee JH, Kim HW, Park H."	Characterization of Two Antimicrobial Peptides from Antarctic Fishes (Notothenia coriiceps and Parachaenichthys charcoti)
DRAMP03950	QKLCMRPSGTWSGVCGNNNACKNQCIRLEKARHGSCNYVFPAHKCICYFPC	51	Rs-AFP2 variant (Mutation: Q5M)	"P30230, Q003I2"	Not found	Not found	Synthetic construct (Mutation of Rs-AFP2)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	"Compared to Rs-AFP2, the mutation Rs-AFP2(Q5M) has increased antifungal potency."	SMF- (synthetic low ionic strength medium): Fusarium culmorum (IC50=4.1¡À0.2); SMF+ (SMF +1 mM CaCl2 and 50 mM KCl): Fusarium culmorum (IC50=5.4¡À1.2)	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8995418	J Biol Chem. 1997 Jan 10;272(2):1171-1179.	"De Samblanx GW, Goderis IJ, Thevissen K, Raemaekers R, Fant F, Borremans F, Acland DP, Osborn RW, Patel S, Broekaert WF."	Mutational analysis of a plant defensin from radish (Raphanus sativus L.) reveals two adjacent sites important for antifungal activity.
DRAMP03951	QKLCQRPSGTWSGVCMNNNACKNQCIRLEKARHGSCNYVFPAHKCICYFPC	51	Rs-AFP2 variant (Mutation: G16M)	"P30230, Q003I2"	Not found	Not found	Synthetic construct (Mutation of Rs-AFP2)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	"Compared to Rs-AFP2, the mutation Rs-AFP2(G16M) has increased antifungal potency."	SMF- (synthetic low ionic strength medium): Fusarium culmorum (IC50=2.2¡À0.3);##SMF+ (SMF + 1 mM CaCl2 and 50 mM KCl): Fusarium culmorum (IC50=5.0¡À0.9).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8995418	J Biol Chem. 1997 Jan 10;272(2):1171-1179.	"De Samblanx GW, Goderis IJ, Thevissen K, Raemaekers R, Fant F, Borremans F, Acland DP, Osborn RW, Patel S, Broekaert WF."	Mutational analysis of a plant defensin from radish (Raphanus sativus L.) reveals two adjacent sites important for antifungal activity.
DRAMP03952	QKLCQRPSRTWSGVCGNNNACKNQCIRLEKARHGSCNYVFPAHKCICYFPC	51	Rs-AFP2 variant (Mutation: G9R)	"P30230, Q003I2"	Not found	Not found	Synthetic construct (Mutation of Rs-AFP2)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	"Compared to Rs-AFP2, the mutation Rs-AFP2(G9R) has increased antifungal potency."	SMF- (synthetic low ionic strength medium): Fusarium culmorum (IC50=3¡À0.5);##SMF+ (SMF + 1 mM CaCl2 and 50 mM KCl): Fusarium culmorum (IC50=3.3¡À0.6).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8995418	J Biol Chem. 1997 Jan 10;272(2):1171-1179.	"De Samblanx GW, Goderis IJ, Thevissen K, Raemaekers R, Fant F, Borremans F, Acland DP, Osborn RW, Patel S, Broekaert WF."	Mutational analysis of a plant defensin from radish (Raphanus sativus L.) reveals two adjacent sites important for antifungal activity.
DRAMP03953	QKLCQRPSGTWSGVCGNNNACKNQCIRLEKARHGSCNYRFPAHKCICYFPC	51	Rs-AFP2 variant (Mutation: V39R)	"P30230, Q003I2"	Not found	Not found	Synthetic construct (Mutation of Rs-AFP2)	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	"Compared to Rs-AFP2, the mutation Rs-AFP2(V39R) has increased antifungal potency."	SMF- (synthetic low ionic strength medium): Fusarium culmorum (IC50=4.0¡À0.2);##SMF+ (SMF + 1 mM CaCl2 and 50 mM KCl): Fusarium culmorum (IC50=3.2¡À0.3).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8995418	J Biol Chem. 1997 Jan 10;272(2):1171-1179.	"De Samblanx GW, Goderis IJ, Thevissen K, Raemaekers R, Fant F, Borremans F, Acland DP, Osborn RW, Patel S, Broekaert WF."	Mutational analysis of a plant defensin from radish (Raphanus sativus L.) reveals two adjacent sites important for antifungal activity.
DRAMP02092	FLPAIAGMAAKFLPKIFCAISKKC	24	"Brevinin-1Bb (Frogs, amphibians, animals)"	P82834	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana berlandieri (Rio Grande leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against the Gram-positive, Gram-negative bacteria and fungi.
Tissue specificity: Expressed by the skin glands."	[Ref.10651828]Gram-positive bacterium: Staphylococcus aureus (MIC=1 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=3 ¦ÌM).##Yeast: Candida albicans (MIC=10 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP04006	GLVSGLLNTAGGLLGDLLGSLGSLSGGES	29	"Plasticin-A1 (PTC-A1; DRP-AA-2-5; frogs, amphibians, animals)"	No entry found	Not found	Not found	Agalychnis annae (AA)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	9774745	Biochim Biophys Acta. 1998 Oct 14;1388(1):279-283.	Wechselberger C.	Cloning of cDNAs encoding new peptides of the dermaseptin-family.
DRAMP18189	IFGAIWKGISSLL	13	"Pantinin-2 (Non-disulfide-bridged peptide 4.21, NDBP-4.21, Non-disulfide-bridged peptide 5.22, ND"	R4JQZ0	 Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short an	Not found	Pandinus imperator (Emperor scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	"Function: Amphipathic peptide that possesses relatively strong activities against Gram-positive bacteria and a fungus, but has very weak antimicrobial activities against Gram-negative bacteria. Also exhibits mild hemolytic activities against human erythrocytes.Forms an alpha-helical membrane channel in the prey."	"[Ref.23624072]Gram-positive bacteria: S.aureus (MIC=48 ¦ÌM), B.magaterium (MIC=36 ¦ÌM), M.luteus (MIC=18 ¦ÌM ), VRE (MIC=36 ¦ÌM), MRSA (MIC=28 ¦ÌM);##Gram-negative bacteria: E.coli (MIC=48 ¦ÌM), P.putida (MIC >87 ¦ÌM), K.oxytoca (MIC >87 ¦ÌM), E.cloacae (MIC >87 ¦ÌM), S.enterica (MIC=68 ¦ÌM);##Fungus: C.tropicalis (MIC=16 ¦ÌM)."	"[Ref.23624072]10% hemolytic activity at 16 ¦ÌM, 80% hemolytic activity at 32 ¦ÌM, 100% hemolytic activity at 64 ¦ÌM against human red bood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	23624072##24184590	Peptides 45:28-34(2013)##Peptides 51:35-45(2014	"Zeng X.C., Zhou L., Shi W., Luo X., Zhang L., Nie Y., Wang J., Wu S.,Cao B., Cao H.##Almaaytah A., Albalas Q."	Three new antimicrobial peptides from the scorpion Pandinusimperator.##Scorpion venom peptides with no disulfide bridges: a review.
DRAMP04008	GLLSGILNTAGGLLGNLIGSLSN	23	"Plasticin-C1 (PTC-C1; DRP-AC-1; frogs, amphibians, animals)"	No entry found	Not found	Not found	Agalychnis callidryas	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12709067	Eur J Biochem. 2003 May;270(9):2068-2081.	"Vanhoye D, Bruston F, Nicolas P, Amiche M."	Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain.
DRAMP04009	GLLSGILNSAGGLLGNLIGSLSN	23	"Plasticin-C2 (PTC-C2; DRP-AC-2; frogs, amphibians, animals)"	No entry found	Not found	Not found	Agalychnis callidryas	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12709067	Eur J Biochem. 2003 May;270(9):2068-2081.	"Vanhoye D, Bruston F, Nicolas P, Amiche M."	Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain.
DRAMP04010	GLVSDLLSTVTGLLGNLGGGGLKKI	25	"Plasticin-S1 (PTC-S1; frogs, amphibians, animals)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Predicted	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18644413	Peptides. 2008 Nov;29(11):2074-2082.	"Amiche M, Ladram A, Nicolas P."	A consistent nomenclature of antimicrobial peptides isolated from frogs of the subfamily Phyllomedusinae.
DRAMP04018	ALYKKFKKKLLKSLKRLG	18	Rp-1	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	"2RLH, 2RLG resolved by NMR."	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria and the yeast candian 	"Gram-positive bacteria: Staphylococcus, Streptococcus, Bacillus species;##Gram-negative bacteria: Escherichia, Salmonella, Pseudomonas species.##Fungi: Candida and Cryptococcus species."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18712851	Biopolymers. 2009 Jan;91(1):1-13.	"Bourbigot S, Dodd E, Horwood C, Cumby N, Fardy L, Welch WH, Ramjan Z, Sharma S, Waring AJ, Yeaman MR, Booth V."	Antimicrobial peptide RP-1 structure and interactions with anionic versus zwitterionic micelles.
DRAMP04037	LKLLKKL	7	Immobilized peptide E07LKK	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04038	LKLLKKLLKLLKKL	14	Immobilized peptide E14LKK/H14LKK	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922 (MBC=1496 ?g/ml), Klebsiella pneumoniae ATCC 4352 (MBC=1496 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923 (MBC=1496 ?g/ml), Bacillus subtilis ATCC 6051 (MBC=1995 ?g/ml).##Yeast: Candida albicans ATCC 10231 (MBC=3200 ?g/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04039	LKLLKKLLKLLKKLGK	16	Immobilized peptige E16KGL/H16KGL	No entry found	Not found	Not found	Synthetic construct 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04040	LKLLKKLLKLLKKLGGK	17	Immobilized peptide E17KGG	No entry found	Not found	Not found	Synthetic construct 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04041	LKLLKKLLKLLKKLGGGK	18	Immobilized peptide E18KGG	No entry found	Not found	Not found	Synthetic construct 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04042	KGLKKLLKLLKKLLKL	16	Immobilized peptide E16LKL	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04043	LKKLLKKLKK	10	Immobilized peptid E10KKL	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04044	LKKLLKKLKKLL	12	Immobilized peptid E12LLK	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04045	LKKLLKKLKKLLKK	14	Immobilized peptid E14KKL	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04046	SNMIEGVFAKGFKKASHLFKGIG	23	Immobilized peptide E23GIG magainin2	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04047	SNMIEGVFAKGFKKASH	17	Immobilized peptide E17HSA magainin 2 deletion	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Has antibacterial activiy against Gram-negative and Gram-positive bacteria.	"Gram-negative bacteria: Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 4352;##Gram-positive bacteria: Staphylococcus aureus ATCC 6538 and ATCC 25923, Bacillus subtilis ATCC 6051.##Yeast: Candida albicans ATCC 10231."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7726486	Antimicrob Agents Chemother. 1995 Feb;39(2):301-307.	"Haynie SL, Crum GA, Doele BA."	Antimicrobial activities of amphiphilic peptides covalently bonded to a water-insoluble resin.
DRAMP04151	IKRFWPVVIRTVVAGYNLYRAIKKK	25	RL1 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04152	KRFWPVVIRTVVAGYNLYRAIKKK	24	RL2 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04153	RFWPVVIRTVVAGYNLYRAIKKK	23	RL3 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04154	FWPVVIRTVVAGYNLYRAIKKK	22	RL4 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04155	WPVVIRTVVAGYNLYRAIKKK	21	RL5 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04156	PVVIRTVVAGYNLYRAIKKK	20	RL6 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04157	VVIRTVVAGYNLYRAIKKK	19	RL7 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04158	VIRTVVAGYNLYRAIKKK	18	RL8 (homologue of Pc-CATH1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Natural Products and Bioprospecting. 2012 Apr;2(2):81-86.	"Li Dong, Juan-Juan Yang, Ying Wang, Huan Liu, Li-Xian Mu, Dong-Hai Lin, Ren Lai."	Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1.
DRAMP04398	AKYTGKCTKSKNECKYKNDAGKDTFIKCPKFDNKKCTKDNNKCTVDTYNNAVDCD	55	Antifungal protein (PAF)	Q01701	Not found	paf	Penicillium chrysogenum (Penicillium notatum)	"Antimicrobial, Antifungal, Antiviral"	Protein level	Beta strand (5 strands; 24 residues)	PAF comprises five beta-strands forming two orthogonally packed beta-sheets that share a common interface.	2KCN resolved by NMR.	Function: It exhibits antifungal activity.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19459942##8566771	FEBS J. 2009 May;276(10):2875-2890.##Gene. 1995 Dec 29;167(1-2):167-171.	"Batta G, Barna T, G¨¢sp¨¢ri Z, S¨¢ndor S, K?v¨¦r KE, Binder U, Sarg B, Kaiserer L, Chhillar AK, Eigentler A, Leiter E, Heged¨¹s N, P¨®csi I, Lindner H, Marx F.##Marx F, Haas H, Reindl M, St?ffler G, Lottspeich F, Redl B."	"Functional aspects of the solution structure and dynamics of PAF--a highly-stable antifungal protein from Penicillium chrysogenum.##oning, structural organization and regulation of expression of the Penicillium chrysogenum paf gene encoding an abundantly secreted protein with antifungal activity."
DRAMP04503	GILTDTLKGAAKNVAGVLLDKLKCKITGGC	30	"Pelophylaxin-1 (Frogs, amphibians, animals)"	Q2WCN8	Not found	pelophylaxin-1	Pelophylax plancyi fukienensis (Fukien gold-striped pond frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Homology	Not found	Not found	None	Function: Amphibian defense peptide.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16139927	Peptides. 2006 Jan;27(1):36-41.	"Zhou M, Chen T, Walker B, Shaw C."	"Pelophylaxins: novel antimicrobial peptide homologs from the skin secretion of the Fukien gold-striped pond frog, Pelophylax plancyi fukienensis: identification by ""shotgun"" cDNA cloning and sequence analysis."
DRAMP04504	GILLNTLKGAAKNVAGVLLDKLKCKITGGC	30	"Pelophylaxin-2 (Frogs, amphibians, animals)"	Q2WCN7	Not found	pelophylaxin-2	Pelophylax plancyi fukienensis (Fukien gold-striped pond frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Homology	Not found	Not found	None	Function: Amphibian defense peptide.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16139927	Peptides. 2006 Jan;27(1):36-41.	"Zhou M, Chen T, Walker B, Shaw C."	"Pelophylaxins: novel antimicrobial peptide homologs from the skin secretion of the Fukien gold-striped pond frog, Pelophylax plancyi fukienensis: identification by ""shotgun"" cDNA cloning and sequence analysis."
DRAMP04505	GLMDSLKGLAATAGKTVLQGLLKTASCKLEKTC	33	"Pelophylaxin-3 (Frogs, amphibians, animals)"	Q2WCN6	Not found	pelophylaxin-3	Pelophylax plancyi fukienensis (Fukien gold-striped pond frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Homology	Not found	Not found	None	Function: Amphibian defense peptide.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16139927	Peptides. 2006 Jan;27(1):36-41.	"Zhou M, Chen T, Walker B, Shaw C."	"Pelophylaxins: novel antimicrobial peptide homologs from the skin secretion of the Fukien gold-striped pond frog, Pelophylax plancyi fukienensis: identification by ""shotgun"" cDNA cloning and sequence analysis."
DRAMP04506	ILPFLAGLFSKIL	13	"Pelophylaxin-4 (Frogs, amphibians, animals)"	Q2WCN5	Not found	pelophylaxin-4	Pelophylax plancyi fukienensis (Fukien gold-striped pond frog)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Homology	Not found	Not found	None	Function: Amphibian defense peptide.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	16139927	Peptides. 2006 Jan;27(1):36-41.	"Zhou M, Chen T, Walker B, Shaw C."	"Pelophylaxins: novel antimicrobial peptide homologs from the skin secretion of the Fukien gold-striped pond frog, Pelophylax plancyi fukienensis: identification by ""shotgun"" cDNA cloning and sequence analysis."
DRAMP04564	FIFHIIKGLFHAGKMIHGLVTRRRH	25	"Epinecidin-1 (Epi-1; fish, animals)"	No entry found	Not found	Not found	Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus)	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	17570764	DNA Cell Biol. 2007 Jun;26(6):403-413.	"Pan CY, Chen JY, Cheng YS, Chen CY, Ni IH, Sheen JF, Pan YL, Kuo CM."	"Gene expression and localization of the epinecidin-1 antimicrobial peptide in the grouper (Epinephelus coioides), and its role in protecting fish against pathogenic infection."
DRAMP04582	IFGSIYHRKCVVKNRCETVSGHKTCKDLTCCRAVIFRHERPEVCRPQT	48	"Strongylocin 1 (Cys-rich; sea urchin, Echinoidea, animals)"	No entry found	Not found	Not found	Strongylocentrotus droebachiensis	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18656496	Dev Comp Immunol. 2008;32(12):1430-1440. 	"Li C, Haug T, Styrvold OB, J?rgensen T?, Stensv?g K."	"Strongylocins, novel antimicrobial peptides from the green sea urchin, Strongylocentrotus droebachiensis."
DRAMP04584	IFNSIYHRKCVVKNRCETVSGHKTCKDLTCCRAVIFRHERPEVCRPST	48	"SpStrongylocin 1 (S. purpuratus Strongylocin, sea urchin, Echinoidea, animals)"	No entry found	Not found	Not found	Strongylocentrotus purpuratus	"Antimicrobial, Antibacterial, Antifungal, Antiviral"	Not found	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19852980	Dev Comp Immunol. 2010 Mar;34(3):286-292.	"Li C, Blencke HM, Smith LC, Karp MT, Stensv?g K."	"Two recombinant peptides, SpStrongylocins 1 and 2, from Strongylocentrotus purpuratus, show antimicrobial activity against Gram-positive and Gram-negative bacteria."
DRAMP04659	FKRLKKLFKKIWNWK	15	HPA3NT3(Derived from HP (2¨C20))	No entry found	Not found	Not found	Helicobacter pylori	"Antimicrobial, Antibacterial, Anti-gram+, Anti-gram-, Antifungal"	Not found	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Trichosporon beigelli"	"[Ref.19642077] Gram-positive bacteria : Staphylococcus aureus(MIC=4 ¦ÌM), Bacillus subtilis(MIC=4 ¦ÌM), Listeria monocytogenes(MIC=22 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=4 ¦ÌM), Salmonella typhimurium(MIC=2 ¦ÌM), Pseudomonas aeruginosa(MIC=2 ¦ÌM);##Fungi : Candida albicans(MIC=8 ¦ÌM), Trichosporon beigelli(MIC=2-4 ¦ÌM)"	"[Ref.19642077] 32% hemolysis at 50 ¦ÌM , 46% hemolysis at 100 ¦ÌM , 70% hemolysis at 200 ¦ÌM against human red blood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22982494##19642077	Biochim Biophys Acta. 2013 Feb;1828(2):443-454.##J Pept Sci.?2009 Sep;15(9):589-94. doi: 10.1002/psc.1155.	"Lee JK, Park SC, Hahm KS, Park Y.##Gopal R, Park SC, Ha KJ, Cho SJ, Kim SW, Song PI, Nah JW, Park Y, Hahm KS"	Antimicrobial HPA3NT3 peptide analogs: Placement of aromatic rings and positive charges are key determinants for cell selectivity and mechanism of action.##Effect of Leucine and Lysine substitution on the antimicrobial activity and evaluation of the mechanism of the HPA3NT3 analog peptide.
DRAMP04660	AKRLKKLFKKIWNWK	15	HPA3NT3-F1A (HPA3NT3 peptide analogs)	No entry found	Not found	Not found	Helicobacter pylori	"Antimicrobial, Antibacterial, Anti-gram+, Anti-gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Trichosporon beigelli, Aspergillus awamori, Aspergillus flavus, Aspergillus fumigatus, Aspergillus parasiticus"	"[Ref.22982494] Gram-positive bacteria : Staphylococcus aureus(MIC=2 ¦ÌM), Listeria monocytogenes(MIC=2 ¦ÌM), Staphylococcus epidermidis(MIC=2-4 ¦ÌM), Bacillus subtilis(MIC=2 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=4 ¦ÌM), Pseudomonas aeruginosa(MIC=1 ¦ÌM), Primula vulgaris(MIC=4 ¦ÌM), Salmonella typhimurium(MIC=1 ¦ÌM);##Fungi : Candida albicans(MIC=8 ¦ÌM), Trichosporon beigelii(MIC=16 ¦ÌM), Aspergillus awamori(MIC=16 ¦ÌM), Aspergillus flavus(MIC=16 ¦ÌM), Aspergillus fumigatus(MIC=8 ¦ÌM), Aspergillus parasiticus(MIC=8 ¦ÌM)"	[Ref.22982494] 7.1% hemolysis at 250 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22982494	Biochim Biophys Acta. 2013 Feb;1828(2):443-454. doi: 10.1016/j.bbamem.2012.09.005	"Lee JK, Park SC, Hahm KS, Park Y."	Antimicrobial HPA3NT3 peptide analogs: Placement of aromatic rings and positive charges are key determinants for cell selectivity and mechanism of action.
DRAMP04661	FKRLKKLAKKIWNWK	15	HPA3NT3-F8A (HPA3NT3 peptide analogs)	No entry found	Not found	Not found	Helicobacter pylori	"Antimicrobial, Antibacterial, Anti-gram+, Anti-gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Trichosporon beigelli, Aspergillus awamori, Aspergillus flavus, Aspergillus fumigatus, Aspergillus parasiticus"	"[Ref.22982494] Gram-positive bacteria : Staphylococcus aureus(MIC=4 ¦ÌM), Listeria monocytogenes(MIC=2 ¦ÌM), Staphylococcus epidermidis(MIC=2-4 ¦ÌM), Bacillus subtilis(MIC=4 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=4 ¦ÌM), Pseudomonas aeruginosa(MIC=2 ¦ÌM), Primula vulgaris(MIC=4 ¦ÌM), Salmonella typhimurium(MIC=2 ¦ÌM);##Fungi : Candida albicans(MIC=8 ¦ÌM), Trichosporon beigelii(MIC=16 ¦ÌM), Aspergillus awamori(MIC=16 ¦ÌM), Aspergillus flavus(MIC=16 ¦ÌM), Aspergillus fumigatus(MIC=8 ¦ÌM), Aspergillus parasiticus(MIC=8 ¦ÌM)"	[Ref.22982494] 4.6% hemolysis at 250 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22982494	Biochim Biophys Acta. 2013 Feb;1828(2):443-454. doi: 10.1016/j.bbamem.2012.09.005	"Lee JK, Park SC, Hahm KS, Park Y."	Antimicrobial HPA3NT3 peptide analogs: Placement of aromatic rings and positive charges are key determinants for cell selectivity and mechanism of action.
DRAMP04662	AKRLKKLAKKIWNWK	15	HPA3NT3-F1AF8A (HPA3NT3 peptide analogs)	No entry found	Not found	Not found	Helicobacter pylori	"Antimicrobial, Antibacterial, Anti-gram+, Anti-gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Trichosporon beigelli, Aspergillus awamori, Aspergillus flavus, Aspergillus fumigatus, Aspergillus parasiticus"	"[Ref.22982494] Gram-positive bacteria : Staphylococcus aureus(MIC=16 ¦ÌM), Listeria monocytogenes(MIC=2 ¦ÌM), Staphylococcus epidermidis(MIC=16 ¦ÌM), Bacillus subtilis(MIC=4 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=32 ¦ÌM), Pseudomonas aeruginosa(MIC=2 ¦ÌM), Primula vulgaris(MIC=4 ¦ÌM), Salmonella typhimurium(MIC=2 ¦ÌM);##Fungi : Candida albicans(MIC=16 ¦ÌM), Trichosporon beigelii(MIC=32 ¦ÌM), Aspergillus awamori(MIC=16 ¦ÌM), Aspergillus flavus(MIC=32 ¦ÌM), Aspergillus fumigatus(MIC=4 ¦ÌM), Aspergillus parasiticus(MIC=8 ¦ÌM)"	[Ref.22982494] 0% hemolysis at 250 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22982494	Biochim Biophys Acta. 2013 Feb;1828(2):443-454. doi: 10.1016/j.bbamem.2012.09.005	"Lee JK, Park SC, Hahm KS, Park Y."	Antimicrobial HPA3NT3 peptide analogs: Placement of aromatic rings and positive charges are key determinants for cell selectivity and mechanism of action.
DRAMP04663	AKRLKKLAKKIWKWL	15	HPA3NT3-A1 (HPA3NT3 peptide analogs)	No entry found	Not found	Not found	Helicobacter pylori	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Trichosporon beigelli, Aspergillus awamori, Aspergillus flavus, Aspergillus fumigatus, Aspergillus parasiticus"	"[Ref.22982494] Gram-positive bacteria : Staphylococcus aureus(MIC=16 ¦ÌM), Listeria monocytogenes(MIC=16 ¦ÌM), Staphylococcus epidermidis(MIC=8 ¦ÌM), Bacillus subtilis(MIC=8 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=32 ¦ÌM), Pseudomonas aeruginosa(MIC=32 ¦ÌM), Primula vulgaris(MIC=8-16 ¦ÌM), Salmonella typhimurium(MIC=8 ¦ÌM);##Fungi : Candida albicans(MIC=16 ¦ÌM), Trichosporon beigelii(MIC>128 ¦ÌM), Aspergillus awamori(MIC=64 ¦ÌM), Aspergillus flavus(MIC=64 ¦ÌM), Aspergillus fumigatus(MIC=16 ¦ÌM), Aspergillus parasiticus(MIC=16 ¦ÌM)"	[Ref.22982494] 20.9% hemolysis at 250 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22982494	Biochim Biophys Acta. 2013 Feb;1828(2):443-454. doi: 10.1016/j.bbamem.2012.09.005	"Lee JK, Park SC, Hahm KS, Park Y."	Antimicrobial HPA3NT3 peptide analogs: Placement of aromatic rings and positive charges are key determinants for cell selectivity and mechanism of action.
DRAMP04664	AKRLKKLAKKIWKWK	15	HPA3NT3-A2 (HPA3NT3 peptide analogs)	No entry found	Not found	Not found	Helicobacter pylori	"Antimicrobial, Antibacterial, Anti-gram+, Anti-gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Trichosporon beigelli, Aspergillus awamori, Aspergillus flavus, Aspergillus fumigatus, Aspergillus parasiticus"	"[Ref.22982494] Gram-positive bacteria : Staphylococcus aureus(MIC=4 ¦ÌM), Listeria monocytogenes(MIC=2 ¦ÌM), Staphylococcus epidermidis(MIC=2-4 ¦ÌM), Bacillus subtilis(MIC=2 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=4 ¦ÌM), Pseudomonas aeruginosa(MIC=2 ¦ÌM), Primula vulgaris(MIC=2-4 ¦ÌM), Salmonella typhimurium(MIC=2 ¦ÌM);##Fungi : Candida albicans(MIC=8 ¦ÌM), Trichosporon beigelii(MIC=16 ¦ÌM), Aspergillus awamori(MIC=8 ¦ÌM), Aspergillus flavus(MIC=8 ¦ÌM), Aspergillus fumigatus(MIC=4 ¦ÌM), Aspergillus parasiticus(MIC=8 ¦ÌM)"	[Ref.22982494] 0% hemolysis at 250 ¦ÌM against human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22982494	Biochim Biophys Acta. 2013 Feb;1828(2):443-454.  doi: 10.1016/j.bbamem.2012.09.005	"Lee JK, Park SC, Hahm KS, Park Y."	Antimicrobial HPA3NT3 peptide analogs: Placement of aromatic rings and positive charges are key determinants for cell selectivity and mechanism of action.
DRAMP18188	GILGKLWEGFKSIV	14	"Pantinin-1 (Non-disulfide-bridged peptide 4.20, NDBP-4.20, Non-disulfide-bridged peptide 5.21, ND"	R4JNJ5	 Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short an	Not found	Pandinus imperator (Emperor scorpion)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Homology	Not found	Not found	None	"Function: Amphipathic peptide that possesses relatively strong activities against Gram-positive bacteria and a fungus, but has very weak antimicrobial activities against Gram-negative bacteria. Also exhibits very low hemolytic activities against human erythrocytes.Forms an alpha-helical membrane channel in the prey."	"[Ref.23624072]Gram-positive bacteria: S.aureus (MIC=8 ¦ÌM), B.magaterium (MIC=32 ¦ÌM), M.luteus (MIC=32 ¦ÌM ), VRE (MIC=28 ¦ÌM), MRSA (MIC=14 ¦ÌM);##Gram-negative bacteria: E.coli (MIC=62 ¦ÌM), P.putida (MIC >87 ¦ÌM), K.oxytoca (MIC >87 ¦ÌM), E.cloacae (MIC=76 ¦ÌM), S.enterica (MIC=72 ¦ÌM);##Fungus: C.tropicalis (MIC=16 ¦ÌM)."	"[Ref.23624072]0% hemolytic activity at 16 ¦ÌM, 0% hemolytic activity at 32 ¦ÌM, 20% hemolytic activity at 64 ¦ÌM against human red bood cells"	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrane	23624072##24184590	Peptides 45:28-34(2013)##Peptides 51:35-45(2014	"Zeng X.C., Zhou L., Shi W., Luo X., Zhang L., Nie Y., Wang J., Wu S.,Cao B., Cao H.##Almaaytah A., Albalas Q."	Three new antimicrobial peptides from the scorpion Pandinusimperator.##Scorpion venom peptides with no disulfide bridges: a review.
DRAMP04673	PAAAAQAVAGLAPVAAEQ	18	Alamethicin (ALM; fungi)	No entry found	Not found	Not found	Trichoderma viride	"Antimicrobial, Antibacterial, Antifungal, Antiparasitic"	Not found	Alpha helix	The molecular conformation of the three crystallographically independent molecules is largely alpha-helical with a bend in the helix axis at an internal proline residue. The helix structure is highly amphipathic as most of the solvent-accessible polar atoms lie on a narrow strip of surface parallel to the helix axis.(Ref.2)	1AMT resolved by X-ray.	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available##6292726	"Experientia, 1967; 23: 85-86.##Nature. 1982 Nov 25;300(5890):325-330."	"Meyer CE, Reusser F.##Fox RO Jr, Richards FM."	Polypeptide anti-bacterial agent isolated from Trichoderma viride.##A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-A resolution.
DRAMP04675	ALSFLFLFLFVAQEIVVTEANTCEHLADTYRGVCFTDASCDDHCKNKAHLISGTCHNFKC	60	Antimicrobial defensin peptide DRR230-c	Q8H6L2	Not found	DRR230-c	Pisum sativum (Garden pea) 	"Antimicrobial, Antifungal"	Transcript level	Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available##6292726	"Plant Sci. 2002, 163:855-864."	"Lai FM, DeLong C, Mei K, Wignes T, Fobert PR."	Analysis of the DRR230 family of pea defensins: gene expression pattern and evidence of broad host-range antifungal activity.
DRAMP04678	DSECLKEYGGDVGFGFCAPRIYPSFCVQRCRADKGALSGKCIWGQGSNVKCLCNFCRHEP	60	Defensin-like protein 4	P80301	Belongs to the DEFL family (RTI/MTI-2 subfamily)	Not found	Brassica napus (Rape)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Function: Inhibits trypsin and chymotrypsin.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8143882	FEBS Lett. 1994 Apr 4;342(2):221-224.	"Ceciliani F, Bortolotti F, Menegatti E, Ronchi S, Ascenzi P, Palmieri S."	"Purification, inhibitory properties, amino acid sequence and identification of the reactive site of a new serine proteinase inhibitor from oil-rape (Brassica napus) seed."
DRAMP04687	GSNIEVMLGLPNSDVK	16	"Glucan endo-1,3-beta-glucosidase, basic vacuolar isoform (Plant defensin)"	P86080	Belongs to the glycosyl hydrolase 17 family	Not found	Capsicum annuum var. annuum (Red pepper)	"Antimicrobial, Antibacterial, Antifungal"	Protein level	Not found	Not found	None	Function: Implicated in the defense of plants against pathogens (By similarity).	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (JUL-2008) to UniProtKB	"Belchi-Navarro S, Almagro L, Pedreno MA."	No title found
DRAMP04688	NIFNAISAAGLGNQIKVSTAIDTGVLGTSYPPSK	34	"Glucan endo-1,3-beta-glucosidase"	P86102	Belongs to the glycosyl hydrolase 17 family	Not found	Vitis rotundifolia (Muscadine grape)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Is thought to be an important plant defense-related product against fungal pathogens.
Miscellaneous: On the 2D-gel the determined pI of this protein is: 6, its MW is: 25 kDa."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19412582	Appl Biochem Biotechnol. 2010 Mar;160(3):932-944.	"Basha SM, Mazhar H, Vasanthaiah HK."	Proteomics approach to identify unique xylem sap proteins in Pierce's disease-tolerant Vitis species.
DRAMP04689	AFVLDADNLIPKKITFGEGSQYGYVKVEGDALSDTLEKIDYETKLVSAPSSSTIIKTTSKYHTKGDVEIKEEHVKAGKEKAAHLFKLIEGYLKDHPSEYN	100	Allergen Fra a 1	Q5ULZ4	Belongs to the BetVI family	Not found	Fragaria ananassa (Strawberry)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: May be involved in ripening of fruits.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15507096	Allergy. 2004 Dec;59(12):1277-1284.	"Karlsson AL, Alm R, Ekstrand B, Fjelkner-Modig S, Schi?tt A, Bengtsson U, Bj?rk L, Hjern? K, Roepstorff P, Emanuelsson CS."	Bet v 1 homologues in strawberry identified as IgE-binding proteins and presumptive allergens.
DRAMP04690	MREETVVYEQEESVSHGGGKHRILAELARVEQEVAFLEKELKEVENTDIVSTVCEELLSVIEKGPDPLLPLTNGPLNLGWDRWFEGPNGGEGCRC	95	Guanine nucleotide-binding protein subunit gamma 1 (Ggamma-subunit 1;Heterotrimeric G protein gam	"Q9FDX9, Q9LY73"	Not found	GG1	Arabidopsis thaliana (Mouse-ear cress)	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	"Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Involved in the abscisic acid (ABA) and ethylene signaling pathways. Regulates acropetal transport of auxin (IAA) in roots and hypocotyls, and thus modulates root architecture (e.g. lateral root formation). The heterotrimeric G- protein controls defense responses to necrotrophic and vascular fungi probably by modulating cell wall-related genes expression; involved in resistance to fungal pathogens such as Alternaria brassicicola, Plectosphaerella cucumerina and Fusarium oxysporum.
Tissue specificity: Mostly expressed in seedlings (especially at the hypocotyl/root junction), young cauline leaves, open flowers, and floral stems, and, to a lower extent, in roots (restricted to the stele), rosette leaves (restricted to veins), siliques, and unopened floral buds. Also present in hydathods.
Developmental stage: In seedlings, first observed at the hypocotyl/root junction but later confined to the hypocotyl. In flowers, restricted to the stigm"	"Fungi: Alternaria brassicicola, Plectosphaerella cucumerina and Fusarium oxysporum."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21980142##17468261	Mol Plant. 2012 Jan;5(1):98-114.##Plant Cell. 2007 Apr;19(4):1235-1250.	"Delgado-Cerezo M, S¨¢nchez-Rodr¨ªguez C, Escudero V, Miedes E, Fern¨¢ndez PV, Jord¨¢ L, Hern¨¢ndez-Blanco C, S¨¢nchez-Vallet A, Bednarek P, Schulze-Lefert P, Somerville S, Estevez JM, Persson S, Molina A.##Trusov Y, Rookes JE, Tilbrook K, Chakravorty D, Mason MG, Anderson D, Chen JG, Jones AM, Botella JR."	Arabidopsis heterotrimeric G-protein regulates cell wall defense and resistance to necrotrophic fungi.##Heterotrimeric G protein gamma subunits provide functional selectivity in Gbetagamma dimer signaling in Arabidopsis.
DRAMP18128	SGTSEKERESGRLLGVVKRLIVGFRSPFR	29	Antimicrobial peptide HsAp4; 	P0DMJ0	Not found	Not found	Heterometrus spinifer (Asia giant forest scorpion) (Malaysian blackscorpion)	"Antimicrobial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	"Function: Possesses antimicrobial activity against both Gram- negative and Gram-positive bacteria, as well as against the fungus C. tropicaliS. Also possess a relatively high hemolytic activity (By similarity)."	"[Ref.23000095]Gram-positive bacteria: Staphylococcus aureus AB 94004 (MIC=23.6?M), Bacillus magaterium AB 90008 (MIC=11.8?M), Bacillus thuringiensis AB 93100 (MIC=46.5?M);##Gram-negative bacteria: Salmonella enterica AB 2010185 (MIC=25.0?M), E. coli DH5 (MIC=51.2?M), E. coli JM109 (MIC=50.4?M), Enterobacter cloacae subsp. cloacae AB 2010162 (MIC=47.9?M), Klebsiella oxytoca AB 2010143 (MIC=50.5?M);##Fungi: Candida tropicalis AY 91009 (MIC=48.6?M)."	"[Ref.23000095]5% hemolytic activity at 0.8 ¦ÌM, 35% hemolytic activity at 1.6 ¦ÌM, 95% hemolytic activity at 3.2 ¦ÌM, 100% hemolytic activity against human red blood cells."	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23000095	Peptides 38:389-394 (2012).	"Nie Y., Zeng X.C. , Yang Y., Luo F., Luo X., Wu S. , Zhang L., Zhou J."	A novel class of antimicrobial peptides from the scorpionHeterometrus spinifer.
DRAMP18129	SGTPEKERESGRLLGVVKRYIVCVRNPCP	29	Antimicrobial peptide HsAp3; 	P0DMI9	Not found	Not found	Heterometrus spinifer (Asia giant forest scorpion) (Malaysian blackscorpion)	"Antimicrobial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	"Function: Possesses antimicrobial activity against both Gram- negative and Gram-positive bacteria, as well as against the fungus C. tropicali. Also possess a relatively high hemolytic activity (By similarity)."	"[Ref.23000095]Gram-positive bacteria: Staphylococcus aureus AB 94004 (MIC=23.6¦ÌM), Bacillus magaterium AB 90008 (MIC=11.8¦ÌM), Bacillus thuringiensis AB 93100 (MIC=46.5¦ÌM);##Gram-negative bacteria: Salmonella enterica AB 2010185 (MIC=25.0¦ÌM), E. coli DH5 (MIC=51.2¦ÌM), E. coli JM109 (MIC=50.4¦ÌM), Enterobacter cloacae subsp. cloacae AB 2010162 (MIC=47.9¦ÌM), Klebsiella oxytoca AB 2010143 (MIC=50.5¦ÌM);##Fungi: Candida tropicalis AY 91009 (MIC=48.6¦ÌM)."	"[Ref.23000095]5% hemolytic activity at 0.8 ¦ÌM, 35% hemolytic activity at 1.6 ¦ÌM, 95% hemolytic activity at 3.2 ¦ÌM, 100% hemolytic activity against human red blood cells."	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23000095	Peptides 38:389-394 (2012).	"Nie Y., Zeng X.C. , Yang Y., Luo F., Luo X., Wu S. , Zhang L., Zhou J."	A novel class of antimicrobial peptides from the scorpionHeterometrus spinifer.
DRAMP18130	SGTSEKERESERLLGVVNPLIKCFRSPCP	29	Antimicrobial peptide HsAp2	P0DMI8	Not found	Not found	Heterometrus spinifer (Asia giant forest scorpion) (Malaysian blackscorpion)	"Antimicrobial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	"Function: Possesses antimicrobial activity against both Gram- negative and Gram-positive bacteria, as well as against the fungus C. tropicaliS. Also possess a relatively high hemolytic activity (By similarity)."	"[Ref.23000095]Gram-positive bacteria: Staphylococcus aureus AB 94004 (MIC=23.6¦ÌM), Bacillus magaterium AB 90008 (MIC=11.8¦ÌM), Bacillus thuringiensis AB 93100 (MIC=46.5¦ÌM);##Gram-negative bacteria: Salmonella enterica AB 2010185 (MIC=25.0¦ÌM), E. coli DH5 (MIC=51.2¦ÌM), E. coli JM109 (MIC=50.4¦ÌM), Enterobacter cloacae subsp. cloacae AB 2010162 (MIC=47.9¦ÌM), Klebsiella oxytoca AB 2010143 (MIC=50.5¦ÌM);##Fungi: Candida tropicalis AY 91009 (MIC=48.6¦ÌM)."	"[Ref.23000095]5% hemolytic activity at 0.8 ¦ÌM, 35% hemolytic activity at 1.6 ¦ÌM, 95% hemolytic activity at 3.2 ¦ÌM, 100% hemolytic activity against human red blood cells."	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23000095	Peptides 38:389-394 (2012).	"Nie Y., Zeng X.C. , Yang Y., Luo F., Luo X., Wu S. , Zhang L., Zhou J."	A novel class of antimicrobial peptides from the scorpionHeterometrus spinifer.
DRAMP18131	SGTSEKERESGRLLGVVKRLIVCFRSPFP	29	Antimicrobial peptide HsAp1 (HsAp)	P0DMI7	Not found	Not found	Heterometrus spinifer (Asia giant forest scorpion) (Malaysian blackscorpion)	"Antimicrobial, Antifungal, Anti-Gram+, Anti-Gram-"	Transcript level	Not found	Not found	None	Function: Possesses antimicrobial activity against both Gram- negative and Gram-positive. Also possess a relatively high hemolytic activity.	"[Ref.23000095]Gram-positive bacteria: Staphylococcus aureus AB 94004 (MIC=23.6¦ÌM), Bacillus magaterium AB 90008 (MIC=11.8¦ÌM), Bacillus thuringiensis AB 93100 (MIC=46.5¦ÌM);##Gram-negative bacteria: Salmonella enterica AB 2010185 (MIC=25.0¦ÌM), E. coli DH5 (MIC=51.2¦ÌM), E. coli JM109 (MIC=50.4¦ÌM), Enterobacter cloacae subsp. cloacae AB 2010162 (MIC=47.9¦ÌM), Klebsiella oxytoca AB 2010143 (MIC=50.5¦ÌM);##Fungi: Candida tropicalis AY 91009 (MIC=48.6¦ÌM)."	"[Ref.23000095]5% hemolytic activity at 0.8 ¦ÌM, 35% hemolytic activity at 1.6 ¦ÌM, 95% hemolytic activity at 3.2 ¦ÌM, 100% hemolytic activity against human red blood cells."	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23000095	Peptides 38:389-394 (2012).	"Nie Y., Zeng X.C. , Yang Y., Luo F., Luo X., Wu S. , Zhang L., Zhou J."	A novel class of antimicrobial peptides from the scorpionHeterometrus spinifer.
DRAMP18185	FLPLFLPKIICVITKKC	17	Jingdongin-1	K7ZGS2	 Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily	Not found	Amolops jingdongensis (Chinese torrent frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function: Has activity against Gram- negative bacterium and exhibits hemolytic activity. 	"[Ref.22828809]Gram-negative bacterium: B.dysenteriae (MIC=35 ¦Ìg/ml);##Gram-positive bacteria: S.aureus ATCC 2592 (MIC=4.7 ¦Ìg/ml), B.subtilis ATCC 6633 (MIC=9.38 ¦Ìg/ml);##Fungus: C.albicans (MIC=18.75 ¦Ìg/ml)"	"[Ref.22828809] It exhibits hemolysis of 1.32%, 5.37%, 6.35%, 16.55% at 25 ¦Ìg/ml, 50 ¦Ìg/ml, 100 ¦Ìg/ml, 200 ¦Ìg/ml against rabbit red blood cells"	Cyclic	Free	Cyclization(Cys11 and Cys17).	Disulfide bond between Cys11 and Cys17.	L	No cytotoxicity information found	Not found	22828809	Amino Acids 44:481-487(2013)	"He X., Yang S., Wei L., Liu R., Lai R., Rong M."	"Antimicrobial peptide diversity in the skin of the torrent frog,Amolops jingdongensis."
DRAMP01297	SGYLPGKEYVYKYKGKVF	18	Longipin (Fragment)	C0HJF8	Not found	Not found	Acutisoma longipes (Neotropical harvestman) (Goniosoma longipes)	"Antimicrobial, Antifungal, Anti-Gram+"	Protein level	Not found	Not found	None	"Function: Has moderate antifungal activity. Has weak antimicrobial activity against the Gram-positive bacterium M. luteus A270 (MIC=83 ??M) but not against S. aureus ATCC 29213 and S. epidermidis ATCC 12228. Inactive against the Gram-negative bacteria P.aeruginosa ATCC 14502, E.coli ATCC 25922 and E.coli SBS 363. Has no hemolytic activity against human erythrocytes at the highest concentration tested (125 ¦ÌM).##Introduction: Constitutively expressed."	"[Swiss_Prot Entry C0HJF8]Fungi: C. albicans MDM8 (MIC=35 ¦ÌM), C. tropicalis IOC 4560 (MIC=63 ¦ÌM), C. guilliermondii IOC 4557 (MIC=32 ¦ÌM), C. albicans IOC 4558 (MIC=125 ¦ÌM);##Gram-positive bacterium: M. luteus A270 (MIC=83 ¦ÌM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	PubMed ID is not available	Submitted (OCT-2013) to the EMBL/GenBank/DDBJ database	Sayegh R.S. R.	"Purification and characterization of antimicrobial peptides presentin the haemolymph of Acutisoma longipes (Gonyleptidae, Opiliones)."
DRAMP18406	KEICCKELTKPVKCSSDPLCQKLCMEKEKYEDGHCFTILSKCLCMKRCNAKTLATELLA	59	CaThi (thionin-like peptide 2; plants)	No entry found	Not found	Not found	"Fruits, Capsicum annuum"	"Antimicrobial, Antifungal"		Bridge	Not found	None	Comment: No comments found on DRAMP database	"Active against C. albicans CE022, C. tropicalis CE017, C. parapsilosis CE002 (IC50 10 ug/ml), C. pelliculosa 3974 (IC50 40 ug/ml), and C. mogii 4674 (IC50 20 ug/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23896704##26819228	Biopolymers. 2014 Jan;102(1):30-9.##BMC Microbiol. 2016 Jan 27;16:12.	"Taveira GB, Mathias LS, da Motta OV, Machado OL, Rodrigues R, Carvalho AO, Teixeira-Ferreira A, Perales J, Vasconcelos IM, Gomes VM.##Taveira GB, Carvalho AO, Rodrigues R, Trindade FG, Da Cunha M, Gomes VM."	Thionin-like peptides from Capsicum annuum fruits with high activity against human pathogenic bacteria and yeasts.##Thionin-like peptide from Capsicum annuum fruits: mechanism of action and synergism with fluconazole against Candida species.
DRAMP18407	KEICCKVPTTPFLCTNDPQCKTLCSKVNYEDGHCFDILSKCVCMNRCVQDAKTLAAELIEEEFLKQ	66	Thionin-like peptide 1 (plants)	No entry found	Not found	Not found	"Fruits, Capsicum annuum"	"Antimicrobial, Antibacterial, Antifungal"		Bridge	Not found	None	Comment: No comments found on DRAMP database	"Active against S. cerevisiae, C. albicans, C. tropicalis, E. coli and P. aeruginosa."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	23896704	Biopolymers. 2014 Jan;102(1):30-9.	"Taveira GB, Mathias LS, da Motta OV, Machado OL, Rodrigues R, Carvalho AO, Teixeira-Ferreira A, Perales J, Vasconcelos IM, Gomes VM."	Thionin-like peptides from Capsicum annuum fruits with high activity against human pathogenic bacteria and yeasts
DRAMP18408	EVCEKASKTWSGNCGNTGHC	20	"Dm-AMP2 (Dahlia defensin, plants)"	No entry found	Belongs to the defensin family.	Not found	"seeds, Dahlia merckii"	"Antimicrobial, Antifungal"		Bridge	Not found	None	"Fuction: The sequence is not yet complete.In medium A supplemented with 1 mM CaCl2 and 50 mM KCl, the peptide is active against fungi B. cinerea (IC50 10 ug/ml), C. sphaerospermum (IC50 3 ug/ml), F. culmorum (IC50 3 ug/ml), L. maculans (IC50 1.0 ug/ml), P. digitatum (IC50 2 ug/ml), S. tritici (IC50 1 ug/ml), and V. albo-atrum (IC50 2 ug/ml)."	"Active against fungi B. cinerea (IC50 10 ug/ml), C. sphaerospermum (IC50 3 ug/ml), F. culmorum (IC50 3 ug/ml), L. maculans (IC50 1.0 ug/ml), P. digitatum (IC50 2 ug/ml), S. tritici (IC50 1 ug/ml), and V. albo-atrum (IC50 2 ug/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7628617	FEBS Lett. 1995 Jul 17;368(2):257-62	"Attenborough S, Rees SB, Broekaert WF. "	"Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae"
DRAMP18409	INWKKIKSIIKAAMN	15	"Mastoparan V1 (MP-V1, insects, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	"Venom; Social Wasp, Vespula vulgaris"	"Antimicrobial, Antibacterial, Antifungal"		Helix	Not found	None	Weak hemolysis 6.6% at 50 uM (20% at 100 uM).	"Active against S. mutans, S. enterica, and S. aureus (MIC 50 uM), and C. albicans, C. grabrata (MIC 50 uM), and C. neoformans (MIC 0.5 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27104500	Molecules. 2016 Apr 19;21(4):512.	"Kim Y, Son M, Noh EY, Kim S, Kim C, Yeo JH, Park C, Lee KW, Bang WY."	MP-V1 from the Venom of Social Wasp Vespula vulgaris Is a de Novo Type of Mastoparan that Displays Superior Antimicrobial Activities.
DRAMP18410	ITCQQVTXELEPCVPYLTQGIP	22	"Cc-LTP2 (Coffea canephora lipid transfer protein 2, plants)"	No entry found	Not found	Not found	"seeds, Coffea canephora Pierre"	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	The sequence is not yet complete.	"Active against Gram- bacteria X. euvesicatoria (inhibition zone of 0.25 mm at 75 ug/ml), and can permeate the memrbane of fungi F. solani at 200 ug/ml."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27813588	Genet Mol Res. 2016 Oct 24;15(4).	"Bard GC, Zottich U, Souza TA, Ribeiro SF, Dias GB, Pireda S, Da Cunha M, Rodrigues R, Pereira LS, Machado OL, Carvalho AO, Gomes VM."	"Purification, biochemical characterization, and antimicrobial activity of a new lipid transfer protein from Coffea canephora seeds."
DRAMP18412	SGYLPGKEYVYKYKGKVF	18	"Longipin (arachnids, Chelicerata, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	"hemolymph, Acutisoma longipes"	"Antimicrobial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against M. luteus A270, Gram- P. aeruginosa ATCC27853, S. marcescens ATCC4112 (MIC 60-120 uM), fungi C. albicans MDM8 (MIC 15-30 uM), C. albicans IOC4558 (7.5-15 uM), C. guilliermondii and C. tropicalis (MIC 3.8-7.5 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27997568	PLoS One. 2016 Dec 20;11(12):e0167953.	"Sayegh RS, Batista IF, Melo RL, Riske KA, Daffre S, Montich G, da Silva Junior PI"	Longipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles
DRAMP18413	FFSMIPKIAGGIASLVKNLG	20	"Phylloseptin-PBa (frog, amphibians, animals)"	No entry found	Not found	Not found	"the Peruvian Purple-Sided Leaf Frog, Phyllomedusa baltea , South America"	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	"Fuction: It exhibited anti-proliferative activity against the human cancer cell lines, H460, PC3 and U251MG, but was less active against a normal human cell line (HMEC)."	"Active against S. aureus (MIC 8 ug/ml), E. coli (MIC 128 ug/ml) and C. albicans (MIC 8 ug/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	26633506	Toxins (Basel). 2015 Dec 1;7(12):5182-93	"Wan Y, Ma C, Zhou M, Xi X, Li L, Wu D, Wang L, Lin C, Lopez JC, Chen T, Shaw C"	Phylloseptin-PBa--A Novel Broad-Spectrum Antimicrobial Peptide from the Skin Secretion of the Peruvian Purple-Sided Leaf Frog (Phyllomedusa Baltea) Which Exhibits Cancer Cell Cytotoxicity.
DRAMP18414	GILGKIWEGVKSLI	14	"NDBP-5.8 (scorpions, arachnids, Chelicerata, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	Opisthacanthus cayaporum	"Antimicrobial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against C. albicans SC5314 (MIC 100 uM), C. tropicalis ATCC 750 (MIC 25 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. neoformans H99 serotype A (MIC 100 uM), and C. neoformans B3501 serotype D (MIC 50 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27917162	Front Microbiol. 2016 Nov 18;7:1844. 	"Guilhelmelli F, Vilela N, Smidt KS, de Oliveira MA, da Cunha Morales ?lvares A, Rigonatto MC, da Silva Costa PH, Tavares AH, de Freitas SM, Nicola AM, Franco OL, Derengowski LD, Schwartz EF, Mortari MR, Bocca AL, Albuquerque P, Silva-Pereira I."	Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms
DRAMP18415	FWSFLVKAASKILPSLIGGGDDNKSSS	27	"Con10 (scorpions, arachnids, Chelicerata, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	Opisthacanthus cayaporum	"Antimicrobial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against C. albicans SC5314 (MIC 100 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoformans H99 serotype A (MIC 50 uM), and C. neoformans B3501 serotype D (MIC 25 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27917162	Front Microbiol. 2016 Nov 18;7:1844	"Guilhelmelli F, Vilela N, Smidt KS, de Oliveira MA, da Cunha Morales ?lvares A, Rigonatto MC, da Silva Costa PH, Tavares AH, de Freitas SM, Nicola AM, Franco OL, Derengowski LD, Schwartz EF, Mortari MR, Bocca AL, Albuquerque P, Silva-Pereira I."	Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms
DRAMP18416	FIGMIPGLIGGLISAIK	17	"ToAP3 (scorpions, arachnids, Chelicerata, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	Tityus obscurus	"Antimicrobial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against C. albicans SC5314 (MIC 25 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 100 uM), C. neoformans H99 serotype A (MIC 100 uM), and C. neoformans B3501 serotype D (MIC 25 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27917162	Front Microbiol. 2016 Nov 18;7:1844	"Guilhelmelli F, Vilela N, Smidt KS, de Oliveira MA, da Cunha Morales ?lvares A, Rigonatto MC, da Silva Costa PH, Tavares AH, de Freitas SM, Nicola AM, Franco OL, Derengowski LD, Schwartz EF, Mortari MR, Bocca AL, Albuquerque P, Silva-Pereira I."	Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms
DRAMP03018	INMKASAAVAKKLL	14	"MP-VB1 (Insects, animals)"	No entry found	Not found	Not found	vespine wasps Vespa bicolor	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Has antimicrobial activities against standard strains and strong antimicrobial ability against drug-resistant strains. Among the tested drug-resistant strains, Pseudemonas aeruginosa and Staphylococcus aureus were the most sensitive for this kind of antimicrobial peptide. Has a little hemolytic activity."	"[Ref.18723059] Gram-negative bacterium: Escherichia coli ATCC25922(MIC=15.0¦Ìg/ml), Escherichia coli 23A(MIC=15.0¦Ìg/ml), Escherichia coli 27A(MIC=60.0¦Ìg/ml), Pseudemonas aeruginosa 3A(MIC=15.0¦Ìg/ml), Pseudemonas aeruginosa 7A(MIC=120.0¦Ìg/ml), ;## Gram-positive bacterium: Staphylococcus aureus ATCC2592(MIC=3.75¦Ìg/ml), Staphylococcus aureus 6A(MIC=1.9¦Ìg/ml), Staphylococcus aureus 15A(MIC=3.75¦Ìg/ml);## Fungus: Candida albicans ATCC2002(MIC=15.0¦Ìg/ml)"	[Ref.18723059] MP-VB1 had almost no hemolytic activity of 1.7% and 2.7% against rabbit and human red blood cells	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	18723059	Peptides. 2008 Nov;29(11):1887-1892.	"Chen W, Yang X, Yang X, Zhai L, Lu Z, Liu J, Yu H."	Antimicrobial peptides from the venoms of Vespa bicolor Fabricius.
DRAMP18428	KRIRFFERIRDRLRDLGNRIKNRIRDFFS	29	"Saha-CATH6 (cathelicidins; mammals, animals)  "	No entry found	Not found	Not found	"Tasmanian devil, Sarcophilus harrisii"	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27725697	Sci Rep. 2016 Oct 11;6:35019	"Peel E, Cheng Y, Djordjevic JT, Fox S, Sorrell TC, Belov K"	Cathelicidins in the Tasmanian devil (Sarcophilus harrisii).
DRAMP18429	KRIGLIRLIGKILRGLRRLG	20	"Saha-CATH5 (cathelicidins; mammals, animals)"	No entry found	Not found	Not found	"Tasmanian devil, Sarcophilus harrisii"	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against E. coli ATCC 25922, P. aeruginosa, E. faecalis, S. aureus ATCC 29213 (MRSA), S. pneumoniae ATCC 49619, S. pyogenes ATCC 19615, S. agalactiae ATCC 12386, S. agalactiae, S. anginosus, S. equi, and C. neoformans (MIC 32-64 ug/mL)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27725697	Sci Rep. 2016 Oct 11;6:35019	"Peel E, Cheng Y, Djordjevic JT, Fox S, Sorrell TC, Belov K"	Cathelicidins in the Tasmanian devil (Sarcophilus harrisii).
DRAMP18430	KRMGIFHLFWAGLRKLGNLIKNKIQQGIENFLG	33	"Saha-CATH3 (cathelicidins; mammals, animals)"	No entry found	Not found	Not found	"Tasmanian devil, Sarcophilus harrisii"	"Antimicrobial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	Active against C. neoformans (MIC 16 ug/mL).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27725697	Sci Rep. 2016 Oct 11;6:35019	"Peel E, Cheng Y, Djordjevic JT, Fox S, Sorrell TC, Belov K"	Cathelicidins in the Tasmanian devil (Sarcophilus harrisii).
DRAMP18431	GHLGRPYIGGGGGFNRGGGFHRGGGFHRGGGFQSGGGFHRGGGFHSGGSFGYR	53	"Armadillidin Q (Gly-rich; Terrestrial Isopod, Crustaceans, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	"haemocytes, Armadillidium vulgare"	"Antimicrobial, Antibacterial, Antifungal"		Rich	Not found	None	Comment: No comments found on DRAMP database	Active against B. megaterium F04 (MBC 4.75 uM) and P. syringae DC3000 (MBC 1.18 uM). 	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrance	27713732	Front Microbiol. 2016 Sep 22;7:1484.	"Verdon J, Coutos-Thevenot P, Rodier MH, Landon C, Depayras S, Noel C, La Camera S, Moumen B, Greve P, Bouchon D, Berjeaud JM, Braquart-Varnier C"	"Armadillidin H, a Glycine-Rich Peptide from the Terrestrial Crustacean Armadillidium vulgare, Displays an Unexpected Wide Antimicrobial Spectrum with Membranolytic Activity"
DRAMP18434	VKSGHYKGPCYHDENCNGVCRDEGYKSGHCSRWGGACWCDT	41	"Cremycin-5 (nematode; invertebrates, animals)"	No entry found	Not found	Not found	Caenorhabditis remanei	"Antimicrobial, Antifungal"		Bridge	Not found	None	Comment: No comments found on DRAMP database	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	24434635	Nat Commun. 2014;5:3154.	"Zhu S, Gao B. "	Nematode-derived drosomycin-type antifungal peptides provide evidence for plant-to-ecdysozoan horizontal transfer of a disease resistance gene
DRAMP18436	RTCESKSHRFKGPCVSTHNCANVCHNEGFGGGKCRGFRRRCYCTRHC	47	AtPDF2.3 (flowering plants)	No entry found	Not found	Not found	Arabidopsis thaliana	"Antimicrobial, Antifungal"		Bridge	Not found	None	Comment: No comments found on DRAMP database	Active against S. cerevisiae.	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27573545	Sci Rep. 2016 Aug 30;6:32121.	"Vriens K, Peigneur S, De Coninck B, Tytgat J, Cammue BP, Thevissen K."	The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels. 
DRAMP18441	SYVGDCGSNGGSCVSSYCPYGNRLNYFCPLGRTCCRRSY	39	"Panusin (beta defensins; crustaceans, arthropods, invertebrates, animals)"	No entry found	Belongs to the beta-defensin family.	Not found	"the Caribbean spiny lobster, Panulirus genus"	"Antimicrobial, Antibacterial, Antifungal"		Bridge	Not found	None	Comment: No comments found on DRAMP database	"Active against E. coli, K. pneumonia, S. aureus, B. subtilisspizizenii, and C. albicans."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27616720	Dev Comp Immunol. 2017 Feb;67:310-321	"Montero-Alejo V, Corzo G, Porro-Suard"	Panusin represents a new family of beta-defensin-like peptides in invertebrates.
DRAMP18442	GVWDWIKKTAGKIWNSEPVKALKSQALNAAKNFVAEKIGATPS	43	"Smp43 (scorpions, arachnids, Chelicerata, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	"venom, Scorpio maurus palmatus"	"Antimicrobial, Antibacterial, Antifungal"		Helix	Not found	None	Comment: No comments found on DRAMP database	"Active against B. subtilis NCIMB 8024 (MIC 4 ug/ml), S. epidermidis sp., S. aureus SH100 (MIC 32-64 ug/ml), E. coli JM109, K. pneumoniae NCTC 13439, and C. albicans (MIC 64-128 ug/ml). "	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrance	27019370	Toxicon. 2016 Jul;117:30-6. 	"Harrison PL, Abdel-Rahman MA, Strong PN, Tawfik MM, Miller K."	Characterisation of three alpha-helical antimicrobial peptides from the venom of Scorpio maurus palmatus
DRAMP18443	IWSFLIKAATKLLPSLFGGGKKDS	24	"Smp24 (scorpions, arachnids, Chelicerata, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	"venom, Scorpio maurus palmatus"	"Antimicrobial, Antibacterial, Antifungal"		Helix	Not found	None	Removal of the N-terminal four residues increases peptide cell selectivity.	"Active against B. subtilis NCIMB 8024, S. epidermidis sp., S. aureus SH100 (MIC 4-8 ug/ml), E. coli JM109 (MIC 64 ug/ml), and C. albicans (MIC 32 ug/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membrance	27019370	Toxicon. 2016 Jul;117:30-6. 	"Harrison PL, Abdel-Rahman MA, Strong PN, Tawfik MM, Miller K."	Characterisation of three alpha-helical antimicrobial peptides from the venom of Scorpio maurus palmatus
DRAMP18448	INNWVRVPPCDQVCSRSNPEKDECCRAHGHAFHAHCNGGMNCYRR	45	"Diapausin-1 (insects, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	"hemolymph, tobacco hornworm, Manduca sexta"	"Antimicrobial, Antifungal"		Bridge	Not found	None	Fuction: Active against FUNGI such as S. cerevisiae (IC50 12 uM) but not bacteria. The peptide is inducible since mRNA level in fact body increased after yeast challege of larvae.	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	26976231	Dev Comp Immunol. 2016 Aug;61:258-68.	"Al Souhail Q, Hiromasa Y, Rahnamaeian M, Giraldo MC, Takahashi D, Valent B, Vilcinskas A, Kanost MR."	"Characterization and regulation of expression of an antifungal peptide from hemolymph of an insect, Manduca sexta."
DRAMP18451	GFLDVVKHIGKAALGAVTHLINQ	23	"CZS-3 (cruzioseptin-3; frog, amphibians, animals)"	No entry found	Not found	Not found	"the splendid leaf frog, Cruziohyla calcarifer, South America"	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against E. coli (13.3 uM), S. aureus (13.3 uM), and C. albicans (13.3 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27321580	J Proteomics. 2016 Sep 2;146:1-13. 	"Proa?o-Bola?os C, Zhou M, Wang L, Coloma LA, Chen T, Shaw C."	"Peptidomic approach identifies cruzioseptins, a new family of potent antimicrobial peptides in the splendid leaf frog, Cruziohyla calcarifer."
DRAMP18452	GFLDVIKHVGKAALGVVTHLINQ	23	"CZS-2 (cruzioseptin-2; frog, amphibians, animals)"	No entry found	Not found	Not found	"the splendid leaf frog, Cruziohyla calcarifer, South America"	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against E. coli (26.3 uM), S. aureus (6.6 uM), and C. albicans (13.2 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27321580	J Proteomics. 2016 Sep 2;146:1-13. 	"Proa?o-Bola?os C, Zhou M, Wang L, Coloma LA, Chen T, Shaw C."	"Peptidomic approach identifies cruzioseptins, a new family of potent antimicrobial peptides in the splendid leaf frog, Cruziohyla calcarifer."
DRAMP18453	GFLDIVKGVGKVALGAVSKLF	21	"CZS-1 (cruzioseptin-1; frog, amphibians, animals)"	No entry found	Not found	Not found	"the splendid leaf frog, Cruziohyla calcarifer, South America"	"Antimicrobial, Antibacterial, Antifungal"		Not found	Not found	None	Comment: No comments found on DRAMP database	"Active against E. coli (15.1 uM), S. aureus (3.8 uM), and C. albicans (3.8 uM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	27321580	J Proteomics. 2016 Sep 2;146:1-13. 	"Proa?o-Bola?os C, Zhou M, Wang L, Coloma LA, Chen T, Shaw C."	"Peptidomic approach identifies cruzioseptins, a new family of potent antimicrobial peptides in the splendid leaf frog, Cruziohyla calcarifer."
DRAMP18455	DSYKKIDCGGACAARCRLSSRPRLCHRACGTCCARCNCVPPGTSGNTETCPCYASLTTHGNKRKCP	66	Tomato Snakin-2 (plants)	No entry found	Not found	Not found	Solanum lycopersicum	"Antimicrobial, Antibacterial, Antifungal"		Bridge	Not found	None	Comment: No comments found on DRAMP database	"Active against E. coli, B. subtilis, and S. cerevisiae."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	21479554##27190708 	Transgenic Res. 2012 Feb;21(1):23-37.##PeerJ. 2016 May 10;4:e1987.	"Balaji V, Smart CD.##Herbel V, Wink M."	Over-expression of snakin-2 and extensin-like protein genes restricts pathogen invasiveness and enhances tolerance to Clavibacter michiganensis subsp. michiganensis in transgenic tomato (Solanum lycopersicum).##Mode of action and membrane specificity of the antimicrobial peptide snakin-2.
DRAMP02081	FLPLLAGLAANFLPKIFCKITRKC	24	"Brevinin-1E (Frogs, amphibians, animals)"	P32412 	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana esculenta (Edible frog) (Pelophylax esculentus)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Anti Mammalian Cells"	Protein level	Alpha helix	Possess an intramo-lecular disulfide bridge located at the  carboxyl-terminal end.	None	"Function: Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and a very high hemolytic activity."	"[Ref.8163497] Gram-negative bacteria: Escherichia coliD21 (MIC=1.8 ?M), Pseudomonas aeruginosa ATCC15692 (MIC=30.6 ?M);##Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=0.4 ?M), Staphylococcus aureus Cowan1 (MIC=0.6 ?M);##Fungi: Candida albicans (MIC=4.7 ?M);##Yeast: Saccharomyces cerevisiae (MIC=3.8 ?M)."	[Ref.8163497] LC50=0.5 ?M against human red blood cell.	Cyclic	Free	Cyclization (Cys18 and Cys24)	Disulfide bond between Cys18 and Cys24.	L	No cytotoxicity information found	Not found	8508915##8163497	FEBS Lett. 1993 Jun 14;324(2):159-161.##J Biol Chem. 1994 Apr 22;269(16):11956-11961. 	"Simmaco M, Mignogna G, Barra D, Bossa F.##Simmaco M, Mignogna G, Barra D, Bossa F."	Novel antimicrobial peptides from skin secretion of the European frog Rana esculenta.##Antimicrobial peptides from skin secretions of Rana esculenta. Molecular cloning of cDNAs encoding esculentin and brevinins and isolation of new active peptides.
DRAMP02094	FLPAIAGVAAKFLPKIFCAISKKC	24	"Brevinin-1Bd (Frogs, amphibians, animals)"	P82836	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana berlandieri (Rio Grande leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against the Gram-positive, Gram-negative bacteria and fungi.
Tissue specificity: Expressed by the skin glands."	[Ref.10651828]Gram-positive bacterium: Staphylococcus aureus (MIC=3 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=7 ¦ÌM).##Yeast: Candida albicans (MIC=7 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP02097	FLPIIAGVAAKVFPKIFCAISKKC	24	"Brevinin-1Pa (Frogs, amphibians, animals)"	P82841	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pipiens (Northern leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against the Gram-positive, Gram-negative bacteria and fungi.
Tissue specificity: Expressed by the skin glands."	[Ref.10651828]Gram-positive bacterium: Staphylococcus aureus (MIC=7 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=14 ¦ÌM).##Yeast: Candida albicans (MIC=5 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP02098	FLPIIASVAAKVFSKIFCAISKKC	24	"Brevinin-1Pc (Frogs, amphibians, animals)"	P82843	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pipiens (Northern leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against the Gram-positive, Gram-negative bacteria and fungi.
Tissue specificity: Expressed by the skin glands."	[Ref.10651828]Gram-positive bacterium: Staphylococcus aureus (MIC=7 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=5 ¦ÌM).##Yeast: Candida albicans (MIC=7 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP02099	FLPIIASVAANVFSKIFCAISKKC	24	"Brevinin-1Pd (Frogs, amphibians, animals)"	P82844	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pipiens (Northern leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity against the Gram-positive, Gram-negative bacteria and fungi.
Tissue specificity: Expressed by the skin glands."	[Ref.10651828]Gram-positive bacterium: Staphylococcus aureus (MIC=27 ¦ÌM);##Gram-negative bacterium: Escherichia coli (MIC=78 ¦ÌM).##Yeast: Candida albicans (MIC=29 ¦ÌM).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP02255	GILSSIKGVAKGVAKNVAAQLLDTLKCKITGC	32	"Ranatuerin-2Lb (Ranatuerin 2Lb; Ranaturin-2PRd; Frogs, amphibians, animals)"	P82829	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana luteiventris (Spotted frog) (Rana pretiosa)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	[Ref.10651828] Gram-positive bacterium: Staphylococcus aureus (MIC=4 ?M);##Gram-negative bacterium: Escherichia coli (MIC=4 ?M);##Yeast: Candida albicans (MIC=62 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP02256	GLLDTIKGVAKTVAASMLDKLKCKISGC	28	"Ranatuerin-2B (Ranatuerin 2B, Frog, amphibians, animals)"	P82840 	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana berlandieri (Rio Grande leopard frog) (Rana luteiventris)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	[Ref.10651828] Gram-positive bacterium: Staphylococcus aureus (MIC=2 ?M);##Gram-negative bacterium: Escherichia coli (MIC=2 ?M);##Yeast: Candida albicans (MIC=35 ?M).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	10651828	Eur J Biochem. 2000 Feb;267(3):894-900.	"Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP02257	LMDTVKNVAKNLAGHMLDKLKCKITGC	27	"Ranatuerin-2P (Ranatuerin 2P; Frogs, amphibians, animals)"	"Q8QFQ4, P82847"	Belongs to the frog skin active peptide family (Brevinin subfamily)	Not found	Rana pipiens (Northern leopard frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal,Antiviral"	Protein level	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	[Ref.10651828] Gram-positive bacteria: Staphylococcus aureus (MIC=50 ?M);##Gram-negative bacterium: Escherichia coli (MIC=13 ?M);##Yeast: Candida albicans (MIC=67 ?M).##[Ref.11601906]Virus:##Frog Virus 3: 90% inhibition at 500 ?M;##Channel Catfish Virus: 99% inhibition at 50 ?M.	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Cyclization of a C-terminal Cys residue (forming a disulfide bond)	There is a disulfide bond between Cys22 and Cys27.	L	No cytotoxicity information found in the reference(s) presented	Not found	11601906##10651828	Virology. 2001 Sep 30;288(2):351-7.##Eur J Biochem. 2000 Feb;267(3):894-900.	"Chinchar VG, Wang J, Murti G, Carey C, Rollins-Smith L.##Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM."	"Inactivation of frog virus 3 and channel catfish virus by esculentin-2P and ranatuerin-2P, two antimicrobial peptides isolated from frog skin.##Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens."
DRAMP18636	KLIFILSKTIPAGKNLFYKI	20	NCP-3a (CTX-1 peptide derivative)	No entry found	Derived from CTX-1	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29364903] Gram-positive bacteria: Methicillin-resistant Staphylococcus aureus ATCC 43300 (MBC=6.3 ¦Ìg/ml), Staphylococcus aureus ATCC 22953 (MBC=12.5 ¦Ìg/ml), Enterococcus hirae ATCC 10541 (MBC=6.3 ¦Ìg/ml), Streptococcus agalactiae ATCC 13813 (MBC=3.1 ¦Ìg/ml);##Gram-negative bacterium: Escherichia coli ATCC 25922 (MBC=6.3 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853 (MBC=25 ¦Ìg/ml), Acinetobacter baumannii (ornithological, cloacal) (MBC=25 ¦Ìg/ml), Acinetobacter baumannii (human, urinary) (MBC=25 ¦Ìg/ml), Klebsiella pneumoniae subsp. pneumoniae (herpetological, cloacal) (MBC=50 ¦Ìg/ml), Burkholderia cepacia ATCC 17759 (MBC=50 ¦Ìg/ml), Moraxella catarrhalis ATCC 25238 (MBC=3.1 ¦Ìg/ml);##Fungi: Candida albicans ATCC 10231 (MBC=6.3 ¦Ìg/mL), Candida glabrata ATCC 90030 (MBC=25 ¦Ìg/mL), Malassezia pachydermatis DSMZ 6172 (MBC=6.3 ¦Ìg/mL)"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	29364903	PLoS One. 2018 Jan 24;13(1):e0190778. 	"Sala A, Cabassi CS, Santospirito D, Polverini E, Flisi S, Cavirani S, Taddei S."	Novel Naja atra cardiotoxin 1 (CTX-1) derived antimicrobial peptides with broad spectrum activity.
DRAMP18637	KLILILSKTIPAGKNLFYKI	20	NCP-3b (CTX-1 peptide derivative)	No entry found	Derived from CTX-1	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29364903] Gram-positive bacteria: Methicillin-resistant Staphylococcus aureus ATCC 43300 (MBC=6.3 ¦Ìg/ml), Staphylococcus aureus ATCC 22953 (MBC=50 ¦Ìg/ml), Enterococcus hirae ATCC 10541 (MBC=12.5 ¦Ìg/ml), Streptococcus agalactiae ATCC 13813 (MBC=12.5 ¦Ìg/ml);##Gram-negative bacterium: Escherichia coli ATCC 25922 (MBC=12.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853 (MBC=25 ¦Ìg/ml), Acinetobacter baumannii (ornithological, cloacal) (MBC=25 ¦Ìg/ml), Acinetobacter baumannii (human, urinary) (MBC=25 ¦Ìg/ml), Klebsiella pneumoniae subsp. pneumoniae (herpetological, cloacal) (MBC=25 ¦Ìg/ml), Burkholderia cepacia ATCC 17759 (MBC=25 ¦Ìg/ml), Moraxella catarrhalis ATCC 25238 (MBC=12.5 ¦Ìg/ml);##Fungi: Candida albicans ATCC 10231 (MBC=12.5 ¦Ìg/mL), Candida glabrata ATCC 90030 (MBC=100 ¦Ìg/mL), Malassezia pachydermatis DSMZ 6172 (MBC=25 ¦Ìg/mL)"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	29364903	PLoS One. 2018 Jan 24;13(1):e0190778. 	"Sala A, Cabassi CS, Santospirito D, Polverini E, Flisi S, Cavirani S, Taddei S."	Novel Naja atra cardiotoxin 1 (CTX-1) derived antimicrobial peptides with broad spectrum activity.
DRAMP18642	KWRWIW	6	KCM12	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: High activity against E. coli DH5	"[Ref.19734717] Gram-negative bacteria: Acidovorax konjaci (MEC=1.3 nM), Pseudomonas syringae pv. tomato DC3000 (MEC=0.3 nM), Escherichia coli DH5¦Á (MEC=1.3 nM), Pseudomonas putida (MEC=0.6 nM), Pectobacterium carotovorum subsp. carotovorum (MEC=5 nM), Pectobacterium carotovorum subsp. atrosepticum (MEC=0.6 nM), Xanthomonas albilineans (MEC=1.3 nM), Xanthomonas campestris pv. vesicatoria 833 (MEC=0.3 nM), Xanthomonas campestris pv. vesicatoria 833 pilA (MEC=0.3 nM), Xanthomonas oryzae pv. oryzae 599 (MEC=0.2 nM), Xanthomonas oryzae pv. oryzae 710 (MEC=0.2 nM), Xanthomonas oryzae pv. oryzae 090 (MEC=0.2 nM);##Gram-positive bacterium: Clavibacter michiganensis subsp. michiganensis (MEC=0.6 nM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19734717	J Microbiol Biotechnol. 2009 Aug;19(8):792-802.	"Choi J, Moon E."	Identification of novel bioactive hexapeptides against phytopathogenic bacteria through rapid screening of a synthetic combinatorial library.
DRAMP18643	KWWWRW	6	KCM21	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: High activity against E. coli DH5	"[Ref.19734717] Gram-negative bacteria: Acidovorax konjaci (MEC=0.6 nM), Pseudomonas syringae pv. tomato DC3000 (MEC=0.6 nM), Escherichia coli DH5¦Á (MEC=1.3 nM), Pseudomonas putida (MEC=1.3 nM), Pectobacterium carotovorum subsp. carotovorum (MEC=5 nM), Pectobacterium carotovorum subsp. atrosepticum (MEC=0.6 nM), Xanthomonas albilineans (MEC=0.2 nM), Xanthomonas campestris pv. vesicatoria 833 (MEC=0.2 nM), Xanthomonas campestris pv. vesicatoria 833 pilA (MEC=0.2 nM), Xanthomonas oryzae pv. oryzae 599 (MEC=0.2 nM), Xanthomonas oryzae pv. oryzae 710 (MEC=0.3 nM), Xanthomonas oryzae pv. oryzae 090 (MEC=0.3 nM);##Gram-positive bacterium: Clavibacter michiganensis subsp. michiganensis (MEC=0.3 nM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19734717	J Microbiol Biotechnol. 2009 Aug;19(8):792-802.	"Choi J, Moon E."	Identification of novel bioactive hexapeptides against phytopathogenic bacteria through rapid screening of a synthetic combinatorial library.
DRAMP18645	RKTWFW	6	PAF19	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	"Function: Antifungal activity against Penicillium digitatum PHI-26, Penicillium italicum PHI-1, Botrytis cinerea CECT2100. All residues of PAF19 are D-animo acids."	"[Ref.11976121] Fungi: Penicillium digitatum PHI-26 (MIC=60 ¦ÌM, IC50=36 ¡À 6 ¦ÌM), Penicillium italicum PHI-1 (MIC=80 ¦ÌM, IC50=52 ¡À 5 ¦ÌM), Botrytis cinerea CECT2100 (MIC=80 ¦ÌM, IC50=43 ¡À 14 ¦ÌM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11976121	Appl Environ Microbiol. 2002 May;68(5):2453-60.	"L¨®pez-Garc¨ªa B, P¨¦rez-Pay¨¢ E, Marcos JF."	Identification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library.
DRAMP18646	RKWHFW	6	PAF32	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	"Function: Antifungal activity against Penicillium digitatum PHI-26, Penicillium italicum PHI-1, Botrytis cinerea CECT2100, Fusarium oxysporum CECT2866, Saccharomyces cerevisiae W303-1A. All residues of PAF32 are D-animo acids."	"[Ref.11976121] Fungi: Penicillium digitatum PHI-26 (MIC=20 ¦ÌM, IC50=7 ¡À 1 ¦ÌM), Penicillium italicum PHI-1 (MIC=20 ¦ÌM, IC50=15 ¡À 5 ¦ÌM), Botrytis cinerea CECT2100 (MIC=40 ¦ÌM, IC50=19 ¡À 8 ¦ÌM), Fusarium oxysporum CECT2866 (MIC=80 ¦ÌM, IC50=56 ¡À 11 ¦ÌM), Saccharomyces cerevisiae W303-1A (MIC>160 ¦ÌM, IC50=63 ¡À 10 ¦ÌM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11976121	Appl Environ Microbiol. 2002 May;68(5):2453-60.	"L¨®pez-Garc¨ªa B, P¨¦rez-Pay¨¢ E, Marcos JF."	Identification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library.
DRAMP18647	RKWLFW	6	PAF34	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	"Function: Antifungal activity against Penicillium digitatum PHI-26, Penicillium italicum PHI-1, Penicillium expansum CMP-1, Botrytis cinerea CECT2100, Saccharomyces cerevisiae W303-1A . Antibacterial activity against Escherichia coli DH5"	"[Ref.11976121] Fungi: Penicillium digitatum PHI-26 (MIC=40 ¦ÌM, IC50=15 ¡À 1 ¦ÌM), Penicillium italicum PHI-1 (MIC=20 ¦ÌM, IC50=12 ¡À 4 ¦ÌM), Penicillium expansum CMP-1 (MIC=160 ¦ÌM, IC50> 80 ¦ÌM), Botrytis cinerea CECT2100 (MIC=60 ¦ÌM), Saccharomyces cerevisiae W303-1A (MIC>160 ¦ÌM, IC50=52 ¡À 22 ¦ÌM);##Gram-negative bacterium: Escherichia coli DH5¦Á(MIC=160 ¦ÌM, IC50>80 ¦ÌM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	11976121	Appl Environ Microbiol. 2002 May;68(5):2453-60.	"L¨®pez-Garc¨ªa B, P¨¦rez-Pay¨¢ E, Marcos JF."	Identification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library.
DRAMP18648	FVPWFSKFLPRIL	13	"[Pro3,DLeu9]TL(3) (Temporin L peptide derivative)"	No entry found	Derived from Temporin L	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	The analogues bearing a D residue showed a reduction in the percentage of helicity compared to the corresponding L analogues in the MMs 	None	"Function: Antimicrobial activity against the Gram-negative bacteria, Gram-positive bacteria and Fungi. The position 9 of [Pro3,DLeu9]TL(3) is D-Leucine, D-Proline replace L-Proline at the position 10 on the  peptide [Pro3,DLeu9]TL(2)."	"[Ref.28863356] Gram-positive bacterium: Bacillus megaterium Bm11 (MIC=3.125¦ÌM), Staphylococcus epidermidis ATCC 12228 (MIC=25¦ÌM);##Gram-negative bacteria: Acinetobacter baumannii ATCC 19606 (MIC=50¦ÌM), Escherichia coli D21 (MIC=50¦ÌM), Pseudomonas syringae pv tabaci 1918 (MIC=50¦ÌM);##Yeasts: Candida albicans ATCC 10231 (MIC=3.125¦ÌM), Candida crusei ATCC 6258 (MIC=3.125¦ÌM)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	28863356	Eur J Med Chem. 2017 Oct 20;139:750-763.	"Merlino F, Carotenuto A, Casciaro B, Martora F, Loffredo MR, Di Grazia A, Yousif AM, Brancaccio D, Palomba L, Novellino E, Galdiero M, Iovene MR, Mangoni ML, Grieco P."	"Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities"
DRAMP18651	SRSELIVHQRRC	12	Cm-p3 (Cm-p1  peptide derivative)	No entry found	Derived from the peptide Cm-p1	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Antifungal activity against Candida albicans and Trichophyton rubrum.	"[Ref.25921828] Fungi: Candida albicans (01U) (MIC=128 ¦Ìg/ml), Candida albicans (38U) (MIC=64 ¦Ìg/ml), Trichophyton rubrum (MIC=128 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	25921828	FASEB J. 2015 Aug;29(8):3315-25. 	"L¨®pez-Abarrategui C, McBeth C, Mandal SM, Sun ZJ, Heffron G, Alba-Men¨¦ndez A, Migliolo L, Reyes-Acosta O, Garc¨ªa-Villarino M, Nolasco DO, Falc?o R, Cherobim MD, Dias SC, Brandt W, Wessjohann L, Starnbach M, Franco OL, Otero-Gonz¨¢lez AJ."	Cm-p5: an antifungal hydrophilic peptide derived from the coastal mollusk Cenchritis muricatus (Gastropoda: Littorinidae).
DRAMP18652	SRSELIVHQRMK	12	Cm-p4 (Cm-p1  peptide derivative)	No entry found	Derived from the peptide Cm-p1	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	"Function: Antifungal activity against Candida albicans, Cryptococcus neoformans and Trichophyton rubrum."	"[Ref.25921828] Fungi: Candida albicans (01U) (MIC=32 ¦Ìg/ml), Candida albicans (38U) (MIC=32 ¦Ìg/ml), Candida parapsilosis (MIC=256 ¦Ìg/ml), Trichophyton rubrum (MIC=32 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	25921828	FASEB J. 2015 Aug;29(8):3315-25. 	"L¨®pez-Abarrategui C, McBeth C, Mandal SM, Sun ZJ, Heffron G, Alba-Men¨¦ndez A, Migliolo L, Reyes-Acosta O, Garc¨ªa-Villarino M, Nolasco DO, Falc?o R, Cherobim MD, Dias SC, Brandt W, Wessjohann L, Starnbach M, Franco OL, Otero-Gonz¨¢lez AJ."	Cm-p5: an antifungal hydrophilic peptide derived from the coastal mollusk Cenchritis muricatus (Gastropoda: Littorinidae).
DRAMP18653	SRSELIVHQRLF	12	Cm-p5 (Cm-p1  peptide derivative)	No entry found	Derived from the peptide Cm-p1	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	"Function: Antifungal activity against Candida albicans, Candida parapsilosis, Cryptococcus neoformans, Trichophyton mentagrophytes and Trichophyton rubrum."	"[Ref.25921828] Fungi: Candida albicans (01U) (MIC=10 ¦Ìg/ml), Candida albicans (38U) (MIC=10 ¦Ìg/ml), Candida parapsilosis (MIC=32 ¦Ìg/ml), Cryptococcus neoformans (L26) (MIC=64 ¦Ìg/ml), Cryptococcus neoformans (L30) (MIC=64 ¦Ìg/ml), Trichophyton mentagrophytes (MIC=128 ¦Ìg/ml), Trichophyton rubrum (MIC=10 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	25921828	FASEB J. 2015 Aug;29(8):3315-25. 	"L¨®pez-Abarrategui C, McBeth C, Mandal SM, Sun ZJ, Heffron G, Alba-Men¨¦ndez A, Migliolo L, Reyes-Acosta O, Garc¨ªa-Villarino M, Nolasco DO, Falc?o R, Cherobim MD, Dias SC, Brandt W, Wessjohann L, Starnbach M, Franco OL, Otero-Gonz¨¢lez AJ."	Cm-p5: an antifungal hydrophilic peptide derived from the coastal mollusk Cenchritis muricatus (Gastropoda: Littorinidae).
DRAMP18657	GDGTGPGPGP	10	"Chitinase (Bacteriocin; Streptomyces violaceusniger, Bacteria)"	P86977	Bacteriocin	Not found	Streptomyces violaceusniger	"Antimicrobial, Antifungal"	Protein level	Not found	Not found	None	Function: Antifungal activity aginst mycelial growth of wood rotting fungi. 	"[Ref.22915152] Inhibits mycelial growth of wood rotting fungi: Phanerochaete chrysosporium MTCC 787 (Inhibition Zone=32.60 mm), Schizophyllum commune ITCC 3751 (Inhibition Zone=27.60 mm), Gloeophyllum trabeum MTCC 355 (Inhibition Zone=30.70 mm), Polyporus agaricans ITCC 761 (Inhibition Zone=25.70 mm),Coriolus versicolor MTCC 138 (Inhibition Zone=20.60 mm), Polystictus versicolor ITCC 13 (Inhibition Zone=16.70 mm), Postia placenta MTCC 144 (Inhibition Zone=20.60 mm), Polyporus friabilis ITCC 335 (Inhibition Zone=22.60 mm)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	22915152	J Basic Microbiol. 2013 May;53(5):429-39. doi: 10.1002/jobm.201100648. Epub 2012 Aug 23.	"Nagpure A, Gupta RK."	Purification and characterization of an extracellular chitinase from antagonistic Streptomyces violaceusniger.
DRAMP18693	RPKPQQFFGLM	11	"Substance P (Mammals, animals)"	"P67932, P67933"	Belongs to the tachykinin family.	TAC1	Not found	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Substance P possesses direct antimicrobial activity. Antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria and fungi."	"[Ref.12074933]Gram-negative bacteria: Escherichia coli (MIC=0.06%), Proteus vulgaris (MIC=0.13%), Pseudomonas aeruginosa (MIC=0.13%) ;##Gram-positive bacteria: Staphylococcus aureus (MIC=0.007%), Enterococcus faecalis (MIC=0.13%);##Yeast: Candida albicans (MIC=0.25%)"	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12074933	Life Sci. 2002 Jul 5;71(7):747-50.	"Kowalska K, Carr DB, Lipkowski AW."	Direct antimicrobial properties of substance P.
DRAMP18694	RPKPQQWFWLM	11	"substance P antagonist (Mammals, animals)"	No entry found	Not found	Not found	Not found	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria and fungi."	"[Ref.12074933]Gram-negative bacteria: Escherichia coli (MIC=0.13%), Proteus vulgaris (MIC=0.13%), Pseudomonas aeruginosa (MIC=0.13%) ;##Gram-positive bacteria: Staphylococcus aureus (MIC=0.13%), Enterococcus faecalis (MIC=0.13%);##Yeast: Candida albicans (MIC=0.03%)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12074933	Life Sci. 2002 Jul 5;71(7):747-50.	"Kowalska K, Carr DB, Lipkowski AW."	Direct antimicrobial properties of substance P.
DRAMP18698	AERVGAGAPVYL	12	"Histone H2A (Trouts, fish, animals)"	P02264	Belongs to the histone H2A family.	Not found	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Protein level	Not found	Not found	None	"Function: The secreted form has antibacterial activity against Gram-positive bacteria and antifungal activity against Saccharomyces cerevisiae.
Tissue specificity: Expressed and secreted by skin epithelium."	"[Ref.12164782] Gram positive bacteria: Aerococcus viridans (MIC=0.08-0.15 ?M), Bacillus subtilis (MIC=0.6-1.2 ?M), Micrococcus luteus (MIC=0.6-1.2 ?M), Planococcus citreus (MIC=0.08-0.15 ?M), Renibacterium salmoninarum (MIC=0.15-0.3 ?M);##Fungi: Saccharomyces cerevisiae (MIC=0.3-0.6 ?M)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	12164782	Biochem J. 2002 Dec 1;368(Pt 2):611-20.	"Fernandes JMO., Kemp GD., Molle MG., Smith VJ.2002"	"Anti-microbial properties of histone H2A from skin secretions of rainbow trout, Oncorhynchus mykiss."
DRAMP18699	FLGGLLASLLGKI	13	"Pleurain-B1 (Frogs, amphibians, animals)"	"B5L1B2, B5L1B4, B5L1B6, B5L1B3"	Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	"[Ref.19028675]Gram-negative bacterium: Escherichia coli(MIC=25 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.1 ¦Ìg/ml), Bacillus subtilis (MIC=3.1 ¦Ìg/ml);##Yeast: Candida albicans (MIC=1.6¦Ìg /ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19028675	Mol Cell Proteomics. 2009 Mar;8(3):571-83.	"Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R."	Antioxidant peptidomics reveals novel skin antioxidant system.
DRAMP18700	YPELQQDLIARLL	13	"Pleurain-C1 (Frogs, amphibians, animals)"	B5L1A8	Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	"[Ref.19028675]Gram-negative bacterium: Escherichia coli (MIC=50 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=6.3 ¦Ìg/ml), Bacillus subtilis (MIC=3.1 ¦Ìg/ml);##Yeast: Candida albicans(MIC=25 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19028675	Mol Cell Proteomics. 2009 Mar;8(3):571-83.	"Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R."	Antioxidant peptidomics reveals novel skin antioxidant system.
DRAMP18701	FRSGILKLASKIPSVLCAVLKNC	23	"Pleurain-D4 (Frogs, amphibians, animals)"	B5L1I4	Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	"[Ref.19028675]Gram-negative bacterium: Escherichia coli (MIC=50 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=12.5 ¦Ìg/ml), Bacillus subtilis (MIC=50 ¦Ìg/ml);##Yeast: Candida albicans(MIC=25 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19028675	Mol Cell Proteomics. 2009 Mar;8(3):571-83.	"Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R."	Antioxidant peptidomics reveals novel skin antioxidant system.
DRAMP18702	AKAWGIPPHVIPQIVPVRIRPLCGNV	26	"Pleurain-E1 (Frogs, amphibians, animals)"	B5L1I5	Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	[Ref.19028675]Gram-negative bacterium: Escherichia coli (MIC=25 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=6..3 ¦Ìg/ml)##Yeast: Candida albicans (MIC=25 ¦Ìg/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19028675	Mol Cell Proteomics. 2009 Mar;8(3):571-83.	"Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R."	Antioxidant peptidomics reveals novel skin antioxidant system.
DRAMP18703	GFWDSVKEGLKNAAVTILNKIKCKISECPPA	31	"Pleurain-G1 (Frogs, amphibians, animals)"	B5L1I8	Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	"[Ref.19028675]Gram-negative bacterium: Escherichia coli (MIC=50 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=50 ¦Ìg/ml), Bacillus subtilis (MIC=100 ¦Ìg/ml);##Yeast: Candida albicans(MIC=12.5 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19028675	Mol Cell Proteomics. 2009 Mar;8(3):571-83.	"Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R."	Antioxidant peptidomics reveals novel skin antioxidant system.
DRAMP18704	FIPGLRRLFATVVPTVVCAINKLPPG	26	"Pleurain-J1 (Frogs, amphibians, animals)"	B5L1L0	Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	"[Ref.19028675]Gram-negative bacterium: Escherichia coli (MIC=12.5 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=12.5 ¦Ìg/ml), Bacillus subtilis (MIC=50 ¦Ìg/ml);##Yeast: Candida albicans(MIC=6.3 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19028675	Mol Cell Proteomics. 2009 Mar;8(3):571-83.	"Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R."	Antioxidant peptidomics reveals novel skin antioxidant system.
DRAMP18705	GFFDRIKALTKNVTLELLNTITCKLPVTPP	30	"Pleurain-N1 (Frogs, amphibians, animals)"	B5L1L8	Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	[Ref.19028675]Gram-negative bacterium: Escherichia coli (MIC=50 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=12.5 ¦Ìg/ml);##Yeast: Candida albicans (MIC=12.5 ¦Ìg/ml).	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19028675	Mol Cell Proteomics. 2009 Mar;8(3):571-83.	"Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R."	Antioxidant peptidomics reveals novel skin antioxidant system.
DRAMP18706	CVHWMTNTARTACIAP	16	"Pleurain-R1 (Frogs, amphibians, animals)"	No entry found	Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.	Not found	Rana pleuraden (Yunnan pond frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	"[Ref.19028675]Gram-negative bacterium: Escherichia coli (MIC=100 ¦Ìg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=25 ¦Ìg/ml), Bacillus subtilis (MIC=100 ¦Ìg/ml);##Yeast: Candida albicans(MIC=50 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	19028675	Mol Cell Proteomics. 2009 Mar;8(3):571-83.	"Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R."	Antioxidant peptidomics reveals novel skin antioxidant system.
DRAMP18708	ALWMTLLKKVLKAAAKAALNAVLVGANA	28	"Dermaseptin-S4 (DRS-S4, DS4; frog, amphibians, animals)"	P80280	Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfami	Not found	Phyllomedusa sauvagei (Sauvage's leaf frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix 	Not found	2DD6 resolved by NMR	"Function: Possesses a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, fungi, protozoa, and the enveloped herpes simplex virus type 1. Probably acts by disturbing membrane functions with its amphipathic structure. Binds to healthy erythrocytes (this binding is receptor independent), and has strong hemolytic activity. Does not bind to P.falciparum infected erythrocytes, but accumulates within the parasite. Kills the parasite, and only at high concentrations has a hemolytic activity on the host cell."	"[Swiss_Prot Entry P80280]Possesses a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, fungi, protozoa, and the enveloped herpes simplex virus type 1"	[Swiss_Prot Entry P80280]Strong hemolytic activity	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	8306981	Eur. J. Biochem. 1994; 219:145-154.	"Mor A, Nicolas P."	Isolation and structure of novel defensive peptides from frog skin.
DRAMP18711	GRKSDCFRKNGFCAFLKCPYLTLISGLCSFHLC	33	"Chicken Heterophil Peptide 2 (CHP-2, avian beta-defensin, birds, animals)"	P80390	Belongs to the beta-defensin family.	Not found	Gallus gallus (Chicken)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge	Not found	None	"Function: Has bactericidal activity. Potent activity against E.coli ML-35, L.monocytogenes EGD and C.albicans."	No MICs found in DRAMP database	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	7964174	J. Leukoc. Biol. 1994; 56: 661-665.	"Evans EW, Beach GG, Wunderlich J, Harmon BG."	Isolation of antimicrobial peptides from avian heterophils.
DRAMP18717	EFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS	37	"Charybdotoxin (Yellow scorpions, arachnids, Chelicerata, arthropods, invertebrates, animals)"	No entry found	Not found	Not found	Leiurus quinquestriatus hebraeus 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Combine Helix and Beta structure 	Not found	2CRD resolved by NMR	"Function: Antimicrobial activity  against Gram-positive bacteria, Gram-negative bacteria and fungi."	"[Ref.15118082]Gram-positive bacteria: Bacillus subtilis (Inhibition zone=4 mm completely inhibit in PH5.5, Inhibition zone=7 mm incompletely inhibit and Inhibition zone=6 mm in PH7.5 completely inhibit at 10 ¦Ìg/well), Staphylococcus aureus  (Inhibition zone=3 mm incompletely inhibit in PH5.5, Inhibition zone=6 mm incompletely inhibit and Inhibition zone=1 mm completely inhibit in PH7.5 at 10 ¦Ìg/well);##Gram-negative bacteria: Escherichia coli (Inhibition zone=2 mm incompletely inhibit in PH5.5, Inhibition zone=8 mm incompletely inhibit in PH7.5 at 10 ¦Ìg/well);##Fungi: Candida albicans (Inhibition zone=13 mm completely inhibit in PH5.5, Inhibition zone=15 mm in PH7.5 completely inhibit at 10 ¦Ìg/well)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not found	15118082	Proc Natl Acad Sci U S A. 2004 May 11;101(19):7363-8.	"Yount NY, Yeaman MR."	Multidimensional signatures in antimicrobial peptides.
DRAMP18721	GWKIGKKLEHHGQNIRDGLISAGPAVFAVGQAATIYAAAK	40	"Hinnavin I (Hin I; insects, arthropods, invertebrates, animals)"	No entry found	Belongs to the Cecropins family.	Not found	Artogeia rapae (cabbage butterfly)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Hinnavin 1 is heat stable; its activity is retained after 60 min incubation at 100 DC, being effective against Gram negative and/or Gram positive bacteria. Hinnavin I and lysozyme 2 showed a powerful synergistic effect on the inhibition of bacterial growth."	"[Ref.9339895] Gram-positive bacteria: Bacillus subtilis (Inhibition zone=3.0 mm), Bacillus megaterium Bm11 (Inhibition zone=5.0 mm), Bacillus thuringiensis (Inhibition zone=3.0 mm);##Gram-negative bacteria: Escherichia coli (Inhibition zone=7.0 mm), Escherichia coli D21 (Inhibition zone=7.1 mm), Enterobacter cloacae (Inhibition zone=6.0 mm);##Fungi: Candida albicans (Inhibition zone=3.0 mm), Aspergillus niger (Inhibition zone=3.0 mm)."	No hemolysis information or data found in the reference(s) presented in this entry	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Not included yet	Cell membranes	9339895	Mol Cells. 1997 Aug 31;7(4):509-13	"Bang IS, Son SY, Yoe SM."	"Hinnavin I, an antibacterial peptide from cabbage butterfly, Artogeia rapae."
DRAMP20778	FFFLSRIF	8	"Temporin-SHf (frogs,amphibians,animals)"	No entry found	Belongs to the Temporin family	Not found	Pelophylax saharica(Sahara frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	"Once bound parallel to the microbial membrane surface, it folds into a non-amphipathic hydrophobic "	None	"Function: Antibacterial activity against the Gram-negative bacteria (Escherichia coli ATCC 25922, Escherichia coli ATCC 35218, Escherichia coli D21, Escherichia coli ML-35p, Pseudomonas aeruginosa ATCC 27853) and Gram-positive bacteria (Staphylococcus aureus ATCC 25923, E. faecalis ATCC 29212, Bacillus megaterium. Antifungal activity)"	[Ref.20308076] Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=25 ¦ÌM); Escherichia coli ATCC 35218(MIC>200 ¦ÌM); Escherichia coli D21(MIC=100 ¦ÌM); Escherichia coli ML-35p(MIC=30 ¦ÌM); Pseudomonas aeruginosa ATCC 27853(MIC>200 ¦ÌM);## Gram-positive bacteria: Staphylococcus aureus ATCC 25923(MIC=12.5 ¦ÌM); E. faecalis ATCC 29212(MIC=50 ¦ÌM); Bacillus megaterium(MIC=3 ¦ÌM);## Yeasts: Candida albicans ATCC 90028(MIC=50 ¦ÌM); C. parapsilosis ATCC 22019(MIC=50 ¦ÌM); S. cerevisiae(MIC=12.5 ¦ÌM);## Fungus(MIC>200 ¦ÌM)	"[Ref.20308076] Temporin-SHf is not cytotoxic against human erythrocytes (LC50 = 200 ¦Ìm), with a hemolytic activity detected only at peptide concentration far above the MIC values determined for the sensitive strains (3¨C50 ¦Ìm) "	Linear	Free	Amidation	None	L	[Ref.20308076] No cytotoxicity information found	Not found	20308076	J Biol Chem. 2010 May 28;285(22):16880-92. 	"Abbassi F, Lequin O, Piesse C, Goasdou"	"Temporin-SHf, a new type of phe-rich and hydrophobic ultrashort antimicrobial peptide."
DRAMP20784	FLKGCWTKWYSLKPKCPF	18	Megin 1	No entry found	Not found	Not found	Amphibian skin	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	The peptide contains an intra-molecular di-sulfide bridge	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. 	[Ref.27114317] Gram-negative bacteria: Escherichia coli (ATCC 25922)(MIC=25¦Ìg/mL);B. dysenteriae(MIC=3¦Ìg/mL);##Gram-positive bacteria:Staphylococcus aureus (ATCC 2592)(MIC=6.25¦Ìg/mL);Bacillus subtilis (ATCC 6633)(MIC=3¦Ìg/mL) ;##Fungi:C.albicans (ATCC 2002)(MIC=50¦Ìg/mL)	[Ref.27114317] Human red blood cells: 2.3% hemolysis at 25¦Ìg/ml; 5.6% hemolysis at 50¦Ìg/ml; 18.7% hemolysis at 100¦Ìg/ml; 29.5% hemolysis at 200¦Ìg/ml. Rabbit red blood cells :3.1% hemolysis at 25¦Ìg/ml; 7.3% hemolysis at 50¦Ìg/ml; 20.5% hemolysis at 100¦Ìg/ml; 32.9% hemolysis at 200¦Ìg/ml	Cyclic	Free	Amidation	Disulfide bond between Cys5 and Cys16	L	No cytotoxicity information found	Not found	27114317	Chin J Nat Med. 2016 Apr;14(4):294-298. 	"Yang HL, Shen ZQ, Liu X, Kong Y."	Two novel antimicrobial peptides from skin venoms of spadefoot toad Megophrys minor.
DRAMP20785	FFVLKFLLKWAGKVGLEHLACKFKNWC	27	Megin 2	No entry found	Not found	Not found	Amphibian skin	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	The peptide contains an intra-molecular di-sulfide bridge	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. 	[Ref.27114317] Gram-negative bacteria: Escherichia coli (ATCC 25922)(MIC=6.25¦Ìg/mL);B. dysenteriae(MIC=1.5¦Ìg/mL);##Gram-positive bacteria:Staphylococcus aureus (ATCC 2592)(MIC=12.5¦Ìg/mL);Bacillus subtilis (ATCC 6633)(MIC=1.5¦Ìg/mL) ;##Fungi:C.albicans (ATCC 2002)(MIC=12.5¦Ìg/mL)	[Ref.27114317] Human red blood cells: 3.9% hemolysis at 25¦Ìg/ml; 13.7% hemolysis at 50¦Ìg/ml; 27.7% hemolysis at 100¦Ìg/ml; 45.3% hemolysis at 200¦Ìg/ml;Rabbit red blood cells: 5.6% hemolysis at 25¦Ìg/ml; 15.2% hemolysis at 50¦Ìg/ml; 36.2% hemolysis at 100¦Ìg/ml; 50.3% hemolysis at 200 ¦Ìg/ml	Cyclic	Free	Free	Disulfide bond between Cys21 and Cys27.	L	No cytotoxicity information found	Not found	27114317	Chin J Nat Med. 2016 Apr;14(4):294-298. 	"Yang HL, Shen ZQ, Liu X, Kong Y."	Two novel antimicrobial peptides from skin venoms of spadefoot toad Megophrys minor.
DRAMP20786	RRLRPRRPRLPRPRPRPRPRPR	22	mini-ChBac7.5N alpha	No entry found	Not found	Not found	Capra hircus	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. 	[Ref.27795854] Gram-negative bacteria: E.coli (ML35p)(MIC=0.3 ¡À 0.1¦ÌM without NaCl;MIC=1.5 ¡À 0.2¦ÌM 100 mM NaCl;MIC=1¦ÌM Broth microdilution assay);E.coli (ATCC 25922)(MIC=0.6 ¡À 0.1¦ÌM without NaCl;MIC=0.9 ¡À 0.2¦ÌM 100 mM NaCl;MIC=2¦ÌM Broth microdilution assay);E.coli (M17)(MIC=0.5 ¡À 0.1¦ÌM without NaCl;MIC=0.8 ¡À 0.1¦ÌM 100 mM NaCl;MIC=2¦ÌM Broth microdilution assay);Pseudomonas aeruginosa (ATCC 27853)(MIC=1.1 ¡À 0.4¦ÌM without NaCl;MIC=3.7 ¡À 1.2¦ÌM 100 mM NaCl;MIC=2¦ÌM Broth microdilution assay);Pseudomonas aeruginosa clinical isolate(MIC=2¦ÌM Broth microdilution assay);Klebsiella spp. clinical isolate(MIC=4¦ÌM Broth microdilution assay);Acinetobacter baumannii clinical isolate(MIC=2¦ÌM Broth microdilution assay);##Gram-positive bacteria:Listeria monocytogenes (EGD)(MIC=0.2 ¡À 0.1¦ÌM without NaCl;MIC=1.0 ¡À 0.2¦ÌM 100 mM NaCl;MIC=2¦ÌM Broth microdilution assay);Micrococcus luteus CIP A270(MIC=1¦ÌM Broth microdilution assay);Staphylococcus aureus (710A)(MIC=0.7 ¡À 0.2¦ÌM without NaCl;MIC> 50¦ÌM 100 mM NaCl;MIC>64¦ÌM Broth microdilution assay);Staphylococcus aureus (ATCC 25923)(MIC>64¦ÌM Broth microdilution assay);MRSA (ATCC 33591)(MIC=0.7 ¡À 0.2¦ÌM without NaCl;MIC> 50¦ÌM 100 mM NaCl;MIC>64¦ÌM Broth microdilution assay);Staphylococcus intermedius clin. isolate(MIC>64¦ÌM Broth microdilution assay);##Fungi:Candida albicans (820)(MIC=0.3 ¡À 0.1¦ÌM without NaCl;MIC> 50¦ÌM 100 mM NaCl;MIC=64¦ÌM Broth microdilution assay);Candida parapsilosis clinical isolate(MIC>64¦ÌM Broth microdilution assay)	[Ref.27818338] No hemolytic activity 	Linear	Free	Free	None	L	"[Ref.27795854] The cytotoxicity values of the experimental samples are not significantly different from the values of the control samples over the entire range of concentrations:1-30 ¦ÌM against various types of cultured human cells: namly, reythroleukemi"	Not found	27795854	Acta Naturae. 2016 Jul-Sep;8(3):136-146.	"Shamova OV, Orlov DS, Zharkova MS, Balandin SV, Yamschikova EV, Knappe D, Hoffmann R, Kokryakov VN, Ovchinnikova TV."	Minibactenecins ChBac7.N
DRAMP20787	RRLRPRRPRLPRPRPRPRPRP	21	mini-ChBac7.5N beta	No entry found	Not found	Not found	Capra hircus	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. 	[Ref.27795854] Gram-negative bacteria:E.coli (ML35p)(MIC=0.3 ¡À 0.1¦ÌM without NaCl;MIC=1.4 ¡À 0.2¦ÌM 100 mM NaCl;MIC=1¦ÌM Broth microdilution assay);E.coli (ATCC 25922)(MIC=0.5 ¡À 0.2¦ÌM without NaCl;MIC=0.8 ¡À 0.2¦ÌM 100 mM NaCl;MIC=2¦ÌM Broth microdilution assay);E.coli (M17)(MIC=0.5 ¡À 0.1¦ÌM without NaCl;MIC=0.9 ¡À 0.2¦ÌM 100 mM NaCl;MIC=1¦ÌM Broth microdilution assay);Pseudomonas aeruginosa (ATCC 27853)(MIC=1.0 ¡À 0.3¦ÌM without NaCl;MIC=3.2 ¡À 0.8¦ÌM 100 mM NaCl;MIC=2¦ÌM Broth microdilution assay);Pseudomonas aeruginosa clinical isolate(MIC=2¦ÌM Broth microdilution assay);Klebsiella spp. clinical isolate(MIC=4¦ÌM Broth microdilution assay);Acinetobacter baumannii clinical isolate(MIC=4¦ÌM Broth microdilution assay);##Gram-positive bacteria:Listeria monocytogenes (EGD)(MIC=0.2 ¡À 0.1¦ÌM without NaCl;MIC=0.9 ¡À 0.2¦ÌM 100 mM NaCl;MIC=2¦ÌM Broth microdilution assay);Micrococcus luteus CIP A270(MIC=1¦ÌM Broth microdilution assay);Staphylococcus aureus (710A)(MIC=0.6 ¡À 0.1¦ÌM without NaCl;MIC> 50¦ÌM 100 mM NaCl;MIC>64¦ÌM Broth microdilution assay);Staphylococcus aureus (ATCC 25923)(MIC>64¦ÌM Broth microdilution assay);MRSA (ATCC 33591)(MIC=0.5 ¡À 0.1¦ÌM without NaCl;MIC> 50¦ÌM 100 mM NaCl;MIC>64¦ÌM Broth microdilution assay);Staphylococcus intermedius clin. isolate(MIC>64¦ÌM Broth microdilution assay);##Fungi:Candida albicans (820)(MIC=0.3 ¡À 0.1¦ÌM without NaCl;MIC> 50¦ÌM 100 mM NaCl;MIC=64¦ÌM Broth microdilution assay);Candida parapsilosis clinical isolate(MIC>64¦ÌM Broth microdilution assay)	[Ref.27818338] No hemolytic activity 	Linear	Free	Free	None	L	"[Ref.27795854] The cytotoxicity values of the experimental samples are not significantly different from the values of the control samples over the entire range of concentrations:1-30 ¦ÌM against various types of cultured human cells: namly, reythroleukemi"	Not found	27795854	Acta Naturae. 2016 Jul-Sep;8(3):136-146.	"Shamova OV, Orlov DS, Zharkova MS, Balandin SV, Yamschikova EV, Knappe D, Hoffmann R, Kokryakov VN, Ovchinnikova TV."	Minibactenecins ChBac7.N
DRAMP20798	QGVRNSQSCRRNKGICVPIRCPGSMRQIGTCLGAQVKCCRRK	42	"Lingual antimicrobial peptide (LAP, beta defensin, cattle, ruminant, animals)"	Q28880	Belongs to the beta-defensin family. LAP/TAP subfamily.	LAP	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Bridge 	Not found	None	"Function: Shows a broad spectrum of antibacterial and antifungal activities.
Tissue specificity: In many of the exposed epithelial surfaces including conjunctivae, bronchi, colon, urinary tract and trachea.
Developmental stage: Not found in fetus."	"[Ref.7886453] Gram-positive bacterium: Staphylococcus aureus 29213 (MIC=63-125 ¦Ìg/ml);##Gram-negative bacteria: Escherichia coli D31 (MIC=16-32 ¦Ìg/ml), Pseudomonas aeruginosa 27853  (MIC=63-125 ¦Ìg/ml);##Fungi: Candida albicans 14053  (MIC=32-63 ¦Ìg/ml), Candida tropicalis 13803 (MIC=16-32 ¦Ìg/ml)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	"Disulfide bonds between Cys9 and Cys38, Cys16 and Cys31, Cys21 and Cys39."	L	[Ref.7886453] No cytotoxicity information found	Not found	7886453	Science. 1995 Mar 17; 267(5204):1645-1648	"Schonwetter BS., Stolzenberg ED., Zasloff MA."	Epithelial antibiotics induced at sites of inflammation.
DRAMP20803	FFRNLWKGAKAAFRAGHAAWRA	22	moronecidin-like peptide	No entry found	Not found	Not found	Hippocampus comes 	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix 	The peptide is Schiffer	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria; antifungal activity.	"[Ref.30039186] Gram-positive bacteria:Staphylococcus aureus ATCC 25923 (MIC=3.12 ¦Ìg/ml),Staphylococcus epidermidis ATCC 1435 (MIC=1.56 ¦Ìg/ml),Staphylococcus aureus MRSA (MIC=3.12 ¦Ìg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC10662 (MIC=50 ¦Ìg/ml),Acinetobacter baumannii clinical isolate (MIC=6.25 ¦Ìg/ml);##Fungi:Candida albicans clinical isolate (MIC=6.25 ¦Ìg/ml), Candida tropicalis clinical isolate (MIC=6.25 ¦Ìg/ml)"	"[Ref.30039186] 50% hemolysis at 87.5¦Ìg/ml,25% hemolysis at 50¦Ìg/ml,60% hemolysis at 100¦Ìg/ml against human red cells"	Linear	Free	Amidation	None	L	[Ref.30039186] No cytotoxicity information found	Not found	30039186	Mar Biotechnol (NY). 2018 Dec;20(6):718-728.	"Mohammadi M, Taheri B, Momenzadeh N, Salarinia R, Nabipour I, Farshadzadeh Z, Bargahi A."	Identification and Characterization of Novel Antimicrobial Peptide from Hippocampus comes by In Silico and Experimental Studies
DRAMP20808	RRLRKKTRKRLKKIGKVLKWI	21	RI21 (PMAP-36 peptide derivative)	No entry found	Derived from PMAP-36	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	"Function: Antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and Fungi.."	"[Ref.27251456] Gram-positive bacteria: Staphylococcus aureus 29213 (MIC=4 ¦ÌM, MBC=4 ¦ÌM), Staphylococcus aureus 25923 (MIC=4 ¦ÌM, MBC=4 ¦ÌM), Staphylococcus epidermidis 12228 (MIC=4 ¦ÌM, MBC=8 ¦ÌM), Bacillus subtilis 63501 (MIC=1 ¦ÌM, MBC=4 ¦ÌM);##Gram-negative bacteria: Escherichia coli 25922 (MIC=2 ¦ÌM, MBC=8 ¦ÌM), Escherichia coli EC183 (MIC=1 ¦ÌM, MBC=2 ¦ÌM), Escherichia coli 1005 (MIC=2 ¦ÌM, MBC=2 ¦ÌM), Salmonella typhimurium C77-31 (MIC=1 ¦ÌM, MBC=2 ¦ÌM);##Fungi: Candida albicans 2.2086 (MIC=8 ¦ÌM, MFC=16 ¦ÌM), Candida albicans CA276 (MIC=8 ¦ÌM, MFC=32 ¦ÌM), Candida tropicalis 2.1975 (MIC=1 ¦ÌM, MFC=2 ¦ÌM), Candida krusei 2.1857 (MIC=2 ¦ÌM, MFC=4 ¦ÌM)."	"[Ref.27251456] 5% hemolysis at 32 ¦ÌM,  MHC=32 ¦ÌM against human red blood cells."	Linear	Free	Amidation	None	L	[Ref.27251456] No cytotoxicity information found	Not found	27251456	Sci Rep. 2016 Jun 2;6:27258. 	"Lyu Y, Yang Y, Lyu X, Dong N, Shan A."	"Antimicrobial activity, improved cell selectivity and mode of action of short PMAP-36-derived peptides against bacteria and Candida."
DRAMP20809	RKKTRKRLKKIGKVLKWI	18	RI18 (PMAP-36 peptide derivative)	No entry found	Derived from PMAP-36	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	"Function: Antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and Fungi.."	"[Ref.27251456] Gram-positive bacteria: Staphylococcus aureus 29213 (MIC=4 ¦ÌM, MBC=4 ¦ÌM), Staphylococcus aureus 25923 (MIC=8 ¦ÌM, MBC=8 ¦ÌM), Staphylococcus epidermidis 12228 (MIC=4 ¦ÌM, MBC=16 ¦ÌM), Bacillus subtilis 63501 (MIC=1 ¦ÌM, MBC=2 ¦ÌM);##Gram-negative bacteria: Escherichia coli 25922 (MIC=2 ¦ÌM, MBC=4 ¦ÌM), Escherichia coli EC183 (MIC=1 ¦ÌM, MBC=2 ¦ÌM), Escherichia coli 1005 (MIC=2 ¦ÌM, MBC=4 ¦ÌM), Salmonella typhimurium C77-31 (MIC=2 ¦ÌM, MBC=4 ¦ÌM);##Fungi: Candida albicans 2.2086 (MIC=16 ¦ÌM, MFC=32 ¦ÌM), Candida albicans CA276 (MIC=8 ¦ÌM, MFC=16 ¦ÌM), Candida tropicalis 2.1975 (MIC=2 ¦ÌM, MFC=4 ¦ÌM), Candida krusei 2.1857 (MIC=4 ¦ÌM, MFC=8 ¦ÌM)."	"[Ref.27251456] 5% hemolysis at 128 ¦ÌM, MHC=128 ¦ÌM against human red blood cells."	Linear	Free	Amidation	None	L	[Ref.27251456] No cytotoxicity information found	Not found	27251456	Sci Rep. 2016 Jun 2;6:27258. 	"Lyu Y, Yang Y, Lyu X, Dong N, Shan A."	"Antimicrobial activity, improved cell selectivity and mode of action of short PMAP-36-derived peptides against bacteria and Candida."
DRAMP20810	TRKRLKKIGKVLKWI	15	TI15 (PMAP-36 peptide derivative)	No entry found	Derived from PMAP-36	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	"Function: Antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and Fungi.."	"[Ref.27251456] Gram-positive bacteria: Staphylococcus aureus 29213 (MIC=32 ¦ÌM, MBC=128 ¦ÌM), Staphylococcus aureus 25923 (MIC=32 ¦ÌM, MBC=128 ¦ÌM), Staphylococcus epidermidis 12228 (MIC=32 ¦ÌM, MBC=64 ¦ÌM), Bacillus subtilis 63501 (MIC=2 ¦ÌM, MBC=4 ¦ÌM);##Gram-negative bacteria: Escherichia coli 25922 (MIC=8 ¦ÌM, MBC=16 ¦ÌM), Escherichia coli EC183 (MIC=2 ¦ÌM, MBC=4 ¦ÌM), Escherichia coli 1005 (MIC=4 ¦ÌM, MBC=8 ¦ÌM), Salmonella typhimurium C77-31 (MIC=8 ¦ÌM, MBC=32 ¦ÌM);##Fungi: Candida albicans 2.2086 (MIC=64 ¦ÌM, MFC=64 ¦ÌM), Candida albicans CA276 (MIC=128 ¦ÌM, MFC=128 ¦ÌM), Candida tropicalis 2.1975 (MIC=2 ¦ÌM, MFC=4 ¦ÌM), Candida krusei 2.1857 (MIC=8 ¦ÌM, MFC=16 ¦ÌM)."	"[Ref.27251456] Non-hemolysis upto 128 ¦ÌM, MHC>128 ¦ÌM against human red blood cells."	Linear	Free	Amidation	None	L	[Ref.27251456] No cytotoxicity information found	Not found	27251456	Sci Rep. 2016 Jun 2;6:27258. 	"Lyu Y, Yang Y, Lyu X, Dong N, Shan A."	"Antimicrobial activity, improved cell selectivity and mode of action of short PMAP-36-derived peptides against bacteria and Candida."
DRAMP20811	RLKKIGKVLKWI	12	RI12 (PMAP-36 peptide derivative)	No entry found	Derived from PMAP-36	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	"Function: Antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and Fungi.."	"[Ref.27251456] Gram-positive bacteria: Staphylococcus aureus 29213 (MIC=64 ¦ÌM, MBC=128 ¦ÌM), Staphylococcus aureus 25923 (MIC=128 ¦ÌM, MBC=128 ¦ÌM), Staphylococcus epidermidis 12228 (MIC=64 ¦ÌM, MBC=64 ¦ÌM), Bacillus subtilis 63501 (MIC=2 ¦ÌM, MBC=8 ¦ÌM);##Gram-negative bacteria: Escherichia coli 25922 (MIC=8 ¦ÌM, MBC=32 ¦ÌM), Escherichia coli EC183 (MIC=2 ¦ÌM, MBC=4 ¦ÌM), Escherichia coli 1005 (MIC=16 ¦ÌM, MBC=32 ¦ÌM), Salmonella typhimurium C77-31 (MIC=8 ¦ÌM, MBC=32 ¦ÌM);##Fungi: Candida albicans 2.2086 (MIC=128 ¦ÌM, MFC=128 ¦ÌM), Candida albicans CA276 (MIC=128 ¦ÌM, MFC=128 ¦ÌM), Candida tropicalis 2.1975 (MIC=8 ¦ÌM, MFC=8 ¦ÌM), Candida krusei 2.1857 (MIC=16 ¦ÌM, MFC=16 ¦ÌM)."	"[Ref.27251456] Non-hemolysis upto 128 ¦ÌM, MHC>128 ¦ÌM against human red blood cells."	Linear	Free	Amidation	None	L	[Ref.27251456] No cytotoxicity information found	Not found	27251456	Sci Rep. 2016 Jun 2;6:27258. 	"Lyu Y, Yang Y, Lyu X, Dong N, Shan A."	"Antimicrobial activity, improved cell selectivity and mode of action of short PMAP-36-derived peptides against bacteria and Candida."
DRAMP20869	GLLKRIKTL	9	Pal-ano-9 (Pal-anoplin peptide derivative)	No entry found	Derived from the peptide Pal-anoplin	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix 	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity. The peptide is palmitoylated.	[Ref.29614317] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=0.406 ¦Ìg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=0.406 ¦Ìg/mL);##Fungi: Candida albicans ATCC 10231 (MIC=3.25 ¦Ìg/mL).	[Ref.29614317] HC50=18.92¦Ìg/mL against human red blood cells	Linear	Acylation (Gly1 conjugated with a palmitoyl group)	Amidation	None	L	[Ref.29614317] No cytotoxicity information found	Not found	29614317	Peptides. 2018 Jun;104:7-14.	"Salas RL, Garcia JKDL, Miranda ACR, Rivera WL, Nellas RB, Sabido PMG."	Effects of truncation of the peptide chain on the secondary structure and bioactivities of palmitoylated anoplin.
DRAMP20870	GLLKRIKT	8	Pal-ano-8 (Pal-anoplin peptide derivative)	No entry found	Derived from the peptide Pal-anoplin	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Random coil	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity. The peptide is palmitoylated.	[Ref.29614317] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=1.63 ¦Ìg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3.25 ¦Ìg/mL);##Fungi: Candida albicans ATCC 10231 (MIC=26 ¦Ìg/mL).	[Ref.29614317] HC50=33.74¦Ìg/mL against human red blood cells	Linear	Acylation (Gly1 conjugated with a palmitoyl group)	Amidation	None	L	[Ref.29614318] No cytotoxicity information found	Not found	29614317	Peptides. 2018 Jun;104:7-14.	"Salas RL, Garcia JKDL, Miranda ACR, Rivera WL, Nellas RB, Sabido PMG."	Effects of truncation of the peptide chain on the secondary structure and bioactivities of palmitoylated anoplin.
DRAMP20871	GLLKRIK	7	Pal-ano-7 (Pal-anoplin peptide derivative)	No entry found	Derived from the peptide Pal-anoplin	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Random coil	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity. The peptide is palmitoylated.	[Ref.29614317] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=0.813 ¦Ìg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=1.63 ¦Ìg/mL);##Fungi: Candida albicans ATCC 10231 (MIC=13 ¦Ìg/mL).	[Ref.29614317] HC50=37.70¦Ìg/mL against human red blood cells	Linear	Acylation (Gly1 conjugated with a palmitoyl group)	Amidation	None	L	[Ref.29614319] No cytotoxicity information found	Not found	29614317	Peptides. 2018 Jun;104:7-14.	"Salas RL, Garcia JKDL, Miranda ACR, Rivera WL, Nellas RB, Sabido PMG."	Effects of truncation of the peptide chain on the secondary structure and bioactivities of palmitoylated anoplin.
DRAMP20872	GLLKRI	6	Pal-ano-6 (Pal-anoplin peptide derivative)	No entry found	Derived from the peptide Pal-anoplin	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix 	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity. The peptide is palmitoylated.	[Ref.29614317] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=0.61 ¦Ìg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=3.25 ¦Ìg/mL);##Fungi: Candida albicans ATCC 10231 (MIC=1.63 ¦Ìg/mL).	[Ref.29614317] HC50=7.51¦Ìg/mL against human red blood cells	Linear	Acylation (Gly1 conjugated with a palmitoyl group)	Amidation	None	L	[Ref.29614320] No cytotoxicity information found	Not found	29614317	Peptides. 2018 Jun;104:7-14.	"Salas RL, Garcia JKDL, Miranda ACR, Rivera WL, Nellas RB, Sabido PMG."	Effects of truncation of the peptide chain on the secondary structure and bioactivities of palmitoylated anoplin.
DRAMP20873	GLLKR	5	Pal-ano-5 (Pal-anoplin peptide derivative)	No entry found	Derived from the peptide Pal-anoplin	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Random coil	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity. The peptide is palmitoylated.	[Ref.29614317] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=3.25 ¦Ìg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=6.5 ¦Ìg/mL);##Fungi: Candida albicans ATCC 10231 (MIC=13 ¦Ìg/mL).	[Ref.29614317] HC50= 66.12¦Ìg/mL against human red blood cells	Linear	Acylation (Gly1 conjugated with a palmitoyl group)	Amidation	None	L	[Ref.29614321] No cytotoxicity information found	Not found	29614317	Peptides. 2018 Jun;104:7-14.	"Salas RL, Garcia JKDL, Miranda ACR, Rivera WL, Nellas RB, Sabido PMG."	Effects of truncation of the peptide chain on the secondary structure and bioactivities of palmitoylated anoplin.
DRAMP20880	RWKFLKKIEKVGRKVRDGVIKAGPAVGVVGQATSIYK	37	DAN2	A0A212F3T6	Belongs to the?cecropin family.	KGM_210265	Monarch butterfly (Danaus plexippus)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Random coil	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29501691] Gram-positive bacteria: Bacillus subtilis (MIC=50¦Ì¡À¦Ì19 ¦Ìg/mL);##Gram-negative bacteria: Escherichia coli (MIC=2.1¦Ì¡À¦Ì0.7 ¦Ìg/mL), Pseudomonas aeruginosa (MIC=5¦Ì¡À¦Ì2.5 ¦Ìg/mL), Klebsiella pneumoniae (MIC=4.3¦Ì¡À¦Ì1.4 ¦Ìg/mL);##Fungi: Candida albicans  (MIC=72.5¦Ì¡À¦Ì35.2 ¦Ìg/mL)"	"[Ref.29501691] 0% haemolysis at 10 ¦Ìg/ml, 0% haemolysis at 25 ¦Ìg/ml, 0% haemolysis at 50 ¦Ìg/ml, 0% haemolysis at 100 ¦Ìg/ml, 0% haemolysis at 200 ¦Ìg/ml against sheep red blood cells"	Linear	Free	Amidation	None	L	[Ref.29501691] No cytotoxicity information found	Not found	29501691	Peptides. 2018 May;103:26-30. doi: 10.1016/j.peptides.2018.01.017.	"Duwadi D, Shrestha A, Yilma B, Kozlovski I, Sa-Eed M, Dahal N, Jukosky J."	Identification and screening of potent antimicrobial peptides in arthropod genomes.
DRAMP20881	VTCDLLSAEAKGVKVNHAACAAHCLLKRKRGGYCNKRRICVCRN	44	HOLO1	D6X2G2	Derived from defensin-like peptides 	Not found	Red flour beetle (Tribolium castaneum)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive bacteria. Antifungal activity against Candida albicans.	"[Ref.29501691] Gram-positive bacteria: Staphylococcus aureus (MIC=13.2¦Ì¡À¦Ì1.8 ¦Ìg/mL), Bacillus subtilis (MIC=6¦Ì¡À¦Ì1.8 ¦Ìg/mL);##Fungi: Candida albicans  (MIC=4.6¦Ì¡À¦Ì1.1 ¦Ìg/mL)"	"[Ref.29501691] 0% haemolysis at 10 ¦Ìg/ml, 0% haemolysis at 25 ¦Ìg/ml, 0% haemolysis at 50 ¦Ìg/ml,  0% haemolysis at 100 ¦Ìg/ml, 0% haemolysis at 200 ¦Ìg/ml against sheep red blood cells"	Linear	Free	Amidation	None	L	[Ref.29501691] No cytotoxicity information found	Not found	29501691	Peptides. 2018 May;103:26-30. doi: 10.1016/j.peptides.2018.01.017.	"Duwadi D, Shrestha A, Yilma B, Kozlovski I, Sa-Eed M, Dahal N, Jukosky J."	Identification and screening of potent antimicrobial peptides in arthropod genomes.
DRAMP20882	ATCDLLSASTPWGSLNHSACAAHCLTKRYKGGRCRNGICRCRR	43	LOUDEF1	E0VPU4	Derived from defensin-like peptides 	8233460 Phum_PHUM365	Human body louse (Pediculhumanus humanus)	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive bacteria. Antifungal activity Candida albicans.	"[Ref.29501691] Gram-positive bacteria: Staphylococcus aureus (MIC=35¦Ì¡À¦Ì1.3 ¦Ìg/mL), Bacillus subtilis (MIC=7¦Ì¡À¦Ì1.6 ¦Ìg/mL);##Fungi: Candida albicans  (MIC= 19.1¦Ì¡À¦Ì9.6 ¦Ìg/mL)"	"[Ref.29501691] 0% haemolysis at 10 ¦Ìg/ml, 0% haemolysis at 25 ¦Ìg/ml, 0% haemolysis at 50 ¦Ìg/ml, 0% haemolysis at 100 ¦Ìg/ml, 0% haemolysis at 200 ¦Ìg/ml against sheep red blood cells"	Linear	Free	Amidation	None	L	[Ref.29501691] No cytotoxicity information found	Not found	29501691	Peptides. 2018 May;103:26-30.	"Duwadi D, Shrestha A, Yilma B, Kozlovski I, Sa-Eed M, Dahal N, Jukosky J."	Identification and screening of potent antimicrobial peptides in arthropod genomes.
DRAMP20887	KLIPILSKTIPAGKNLFYKI	20	NCP-2 (CTX-1 peptide derivative)	No entry found	Derived from CTX-1	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	"The peptide adopts a conformational structure with 20 % alpha helix, 25 % beta sheet and 35 % random coil in the presence of DMPE-DMPG mixed vesicles."	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29364903] Gram-positive bacteria: Staphylococcus aureus ATCC 22953 (MBC=50 ¦Ìg/ml), Streptococcus agalactiae ATCC 13813 (MBC=12.5 ¦Ìg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MBC=12.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853 (MBC=12.5 ¦Ìg/ml), Acinetobacter baumannii (herpetological, cloacal) (MBC=1.6 ¦Ìg/ml), Acinetobacter baumannii (ornithological, cloacal) (MBC=50 ¦Ìg/ml), Acinetobacter baumannii (human, urinary) (MBC=1.6 ¦Ìg/ml), Moraxella catarrhalis ATCC 25238 (MBC=1.6 ¦Ìg/ml);##Fungi: Candida albicans ATCC 10231 (MBC=50 ¦Ìg/mL), Malassezia pachydermatis DSMZ 6172 (MBC=6.3 ¦Ìg/mL)"	"[Ref.29364903] 2% haemolysis at 12.5 ¦Ìg/ml, 8% haemolysis at 100.0 ¦Ìg/ml against sheep red blood cells"	Linear	Free	Free	None	L	[Ref.29364903] The cell death rate of Madin-Darby Bovine Kidney(MDBK) cells is 3 % and 5% at peptide concentrations of 12.5 and 100  ¦Ìg/ml	Not found	29364903	PLoS One. 2018 Jan 24;13(1):e0190778. 	"Sala A, Cabassi CS, Santospirito D, Polverini E, Flisi S, Cavirani S, Taddei S."	Novel Naja atra cardiotoxin 1 (CTX-1) derived antimicrobial peptides with broad spectrum activity.
DRAMP20888	KLIWILSKTIPAGKNLFYKI	20	NCP-3 (CTX-1 peptide derivative)	No entry found	Derived from CTX-1	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	The peptide adopts a conformational structure with 43 % beta sheet and 35 % random coil in the presence of DMPE-DMPG mixed vesicles.	None	"Function: Antimicrobial activity against the Gram-positive bacteria, Gram-negative bacteria and fungi. NCP-3 completely inhibits the viral activity of BoHV-1 on MDBK cells at the concentration of 25 "	"[Ref.29364903] Gram-positive bacteria: Methicillin-resistant Staphylococcus aureus ATCC 43300 (MBC=6.3 ¦Ìg/ml), Staphylococcus aureus ATCC 22953 (MBC=1.6 ¦Ìg/ml), Enterococcus hirae ATCC 10541 (MBC=1.6 ¦Ìg/ml), Streptococcus agalactiae ATCC 13813 (MBC=1.6 ¦Ìg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MBC=12.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853 (MBC=12.5 ¦Ìg/ml), Acinetobacter baumannii (herpetological, cloacal) (MBC=1.6 ¦Ìg/ml), Acinetobacter baumannii (ornithological, cloacal) (MBC=6.3 ¦Ìg/ml), Acinetobacter baumannii (human, urinary) (MBC=1.6 ¦Ìg/ml), Klebsiella pneumoniae subsp. pneumoniae (herpetological, cloacal) (MBC=50 ¦Ìg/ml), Enterobacter cloacae (herpetological, cloacal) (MBC=25 ¦Ìg/ml), Burkholderia cepacia ATCC 17759 (MBC=50 ¦Ìg/ml), Moraxella catarrhalis ATCC 25238 (MBC=1.6 ¦Ìg/ml);##Fungi: Candida albicans ATCC 10231 (MBC=12.5 ¦Ìg/mL), Candida glabrata ATCC 90030 (MBC=50 ¦Ìg/mL), Malassezia pachydermatis DSMZ 6172 (MBC=6.3 ¦Ìg/mL)."	"[Ref.29364903] 3% haemolysis at 12.5 ¦Ìg/ml, 9% haemolysis at 100.0 ¦Ìg/ml against sheep red blood cells"	Linear	Free	Free	None	L	[Ref.29364903] The cell death rate of Madin-Darby Bovine Kidney(MDBK) cells is 3 % and 7% at peptide concentrations of 12.5 and 100  ¦Ìg/ml	Not found	29364903	PLoS One. 2018 Jan 24;13(1):e0190778. 	"Sala A, Cabassi CS, Santospirito D, Polverini E, Flisi S, Cavirani S, Taddei S."	Novel Naja atra cardiotoxin 1 (CTX-1) derived antimicrobial peptides with broad spectrum activity.
DRAMP20892	FIAAIIGGLFSAGKAIHRLIRRRRR	25	H3A/H4A	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Synthetic	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive bacteria. Antifungal activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=32 ¦Ìg/ml; MBC=32 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=128 ¦Ìg/ml; MBC=256 ¦Ìg/ml);##Fungi: Candida albicans (MIC=512 ¦Ìg/ml; MBC=512 ¦Ìg/ml)"	"[Ref.29040295] 7% haemolysis at 1.56 ¦Ìg/ml, 10% haemolysis at 3.13 ¦Ìg/ml, 70% haemolysis at 6.25 ¦Ìg/ml, 95% haemolysis at 12.50 ¦Ìg/ml, 98% haemolysis at 25.00 ¦Ìg/ml, 100% haemolysis at 50.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20893	FIHHIIGGLFSAGKAAHRLIRRRRR	25	I16A	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=64 ¦Ìg/ml; MBC=128 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=64 ¦Ìg/ml; MBC=512 ¦Ìg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=256 ¦Ìg/ml; MBC>512 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)"	"[Ref.29040295] 10% haemolysis at 6.25 ¦Ìg/ml, 20% haemolysis at 12.50 ¦Ìg/ml, 35% haemolysis at 25.00 ¦Ìg/ml, 80% haemolysis at 50.00 ¦Ìg/ml, 95% haemolysis at 100.00 ¦Ìg/ml, 100% haemolysis at 200.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20894	FIHHIIGGLFSAGKAIHRHHRRRRR	25	L19H/I20H	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=128 ¦Ìg/ml; MBC=512 ¦Ìg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=256 ¦Ìg/ml; MBC>512 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)	"[Ref.29040295] 10% haemolysis at 6.25 ¦Ìg/ml, 13% haemolysis at 12.50 ¦Ìg/ml, 16% haemolysis at 25.00 ¦Ìg/ml, 40% haemolysis at 50.00 ¦Ìg/ml, 85% haemolysis at 100.00 ¦Ìg/ml, 100% haemolysis at 200.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20895	AAHHIIGGLFSAGKAIHRLIRRRRR	25	F1A/I2A	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=128 ¦Ìg/ml; MBC=256 ¦Ìg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=256 ¦Ìg/ml; MBC=256 ¦Ìg/ml);##Fungi: Candida albicans (MIC=64 ¦Ìg/ml; MBC=128 ¦Ìg/ml)	"[Ref.29040295] 10% haemolysis at 12.50 ¦Ìg/ml,  15% haemolysis at 25.00 ¦Ìg/ml,  30% haemolysis at 50.00 ¦Ìg/ml,  90% haemolysis at 100.00 ¦Ìg/ml,  95% haemolysis at 200.00 ¦Ìg/ml,  100% haemolysis at 400.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20896	FIHHIIGGAASAGKAIHRLIRRRRR	25	L9A/F10A	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Antifungal activity.	[Ref.29040295] Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)	"[Ref.29040295] 5% haemolysis at 25.00 ¦Ìg/ml,  10% haemolysis at 50.00 ¦Ìg/ml,  30% haemolysis at 100.00 ¦Ìg/ml,  95% haemolysis at 200.00 ¦Ìg/ml,  100% haemolysis at 400.00 ¦Ìg/ml,  100% haemolysis at 800.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20897	FIHHIIGGLFSAGKARHRLIRRRRR	25	I16R	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Antifungal activity.	[Ref.29040295] Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=256 ¦Ìg/ml)	"[Ref.29040295] 10% haemolysis at 25.00 ¦Ìg/ml,  20% haemolysis at 50.00 ¦Ìg/ml,  30% haemolysis at 100.00 ¦Ìg/ml,  75% haemolysis at 200.00 ¦Ìg/ml,  95% haemolysis at 400.00 ¦Ìg/ml,  100% haemolysis at 800.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20898	FIHHIIGGLFSAGKAEHRLIRRRRR	25	I16E	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic	Not found	Not found	None	Function: Antifungal activity.	[Ref.29040295] Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)	"[Ref.29040295] 5% haemolysis at 25.00 ¦Ìg/ml,  15% haemolysis at 50.00 ¦Ìg/ml,  40% haemolysis at 100.00 ¦Ìg/ml,  65% haemolysis at 200.00 ¦Ìg/ml,  85% haemolysis at 400.00 ¦Ìg/ml,  90% haemolysis at 800.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20899	FIHHAAGGLFSAGKAIHRLIRRRRR	25	I5A/I6A	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	Function: Antibacterial activity against the Gram-negative bacteria. Antifungal activity.	[Ref.29040295] Gram-negative bacteria: Pseudomonas aeruginosa (MIC=512 ¦Ìg/ml; MBC=512 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)	"[Ref.29040295] 5% haemolysis at 25.00 ¦Ìg/ml,  7% haemolysis at 50.00 ¦Ìg/ml,  10% haemolysis at 100.00 ¦Ìg/ml,  40% haemolysis at 200.00 ¦Ìg/ml,  80% haemolysis at 400.00 ¦Ìg/ml,  100% haemolysis at 800.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20900	FIHHIIGGLFSIGKIIHRLIRRRRR	25	A12I/A15I	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=16 ¦Ìg/ml; MBC=64 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=64 ¦Ìg/ml; MBC=256 ¦Ìg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=512 ¦Ìg/ml; MBC>512 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)"	"[Ref.29040295] 0% haemolysis at 0.20 ¦Ìg/ml,  5% haemolysis at 0.39 ¦Ìg/ml,  25% haemolysis at 0.78 ¦Ìg/ml,  85% haemolysis at 1.56 ¦Ìg/ml,  95% haemolysis at 3.13 ¦Ìg/ml,  100% haemolysis at 6.25 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20901	FIHHIIGGLFSVGKHIHRLIRRRRR	25	A12V/A15H	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=16 ¦Ìg/ml; MBC=16 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=32 ¦Ìg/ml; MBC=64 ¦Ìg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)"	"[Ref.29040295] 0% haemolysis at 0.78 ¦Ìg/ml,  10% haemolysis at 1.56 ¦Ìg/ml,  55% haemolysis at 3.13 ¦Ìg/ml,  85% haemolysis at 6.25 ¦Ìg/ml,  98% haemolysis at 12.50 ¦Ìg/ml,  100% haemolysis at 25.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20902	FIHHIIGGLFSVGKHIHSLIHRRRR	25	VHSH	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Synthetic	Not found	Not found	None	Function: Antibacterial activity against the Gram-positive bacteria. Antifungal activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=16 ¦Ìg/ml; MBC=16 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=16 ¦Ìg/ml; MBC=32 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)"	"[Ref.29040295] 5% haemolysis at 1.56 ¦Ìg/ml,  5% haemolysis at 3.13 ¦Ìg/ml,  10% haemolysis at 6.25 ¦Ìg/ml,  35% haemolysis at 12.50 ¦Ìg/ml,  55% haemolysis at 25.00 ¦Ìg/ml,  85% haemolysis at 50.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20903	FIHHIIGGLFSAGKAIHRLIRRR	23	dC2	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=16 ¦Ìg/ml; MBC=32 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=32 ¦Ìg/ml; MBC=32 ¦Ìg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=512 ¦Ìg/ml; MBC>512 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)"	"[Ref.29040295] 2% haemolysis at 3.13 ¦Ìg/ml,  5% haemolysis at 6.25 ¦Ìg/ml,  25% haemolysis at 12.50 ¦Ìg/ml,  65% haemolysis at 25.00 ¦Ìg/ml,  90% haemolysis at 50.00 ¦Ìg/ml,  100% haemolysis at 100.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20904	FIHHIIGGLFSAGKAIHSLIHRRRR	25	R18S/R21H	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=32 ¦Ìg/ml; MBC=64 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=32 ¦Ìg/ml; MBC=32 ¦Ìg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=256 ¦Ìg/ml; MBC=512 ¦Ìg/ml);##Fungi: Candida albicans (MIC=256 ¦Ìg/ml; MBC=512 ¦Ìg/ml)"	"[Ref.29040295] 8% haemolysis at 6.25 ¦Ìg/ml,  10% haemolysis at 12.50 ¦Ìg/ml,  15% haemolysis at 25.00 ¦Ìg/ml,  40% haemolysis at 50.00 ¦Ìg/ml,  80% haemolysis at 100.00 ¦Ìg/ml,  100% haemolysis at 200.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20905	FIHHIIGGLFSAGKAIHRLIR	21	dC4	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Synthetic	Alpha helix	Not found	None	Function: Antibacterial activity against the Gram-positive bacteria. Antifungal activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=64 ¦Ìg/ml; MBC=128 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=256 ¦Ìg/ml; MBC=256 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=256 ¦Ìg/ml)"	"[Ref.29040295] 5% haemolysis at 12.50 ¦Ìg/ml,  10% haemolysis at 25.00 ¦Ìg/ml,  45% haemolysis at 50.00 ¦Ìg/ml,  80% haemolysis at 100.00 ¦Ìg/ml,  100% haemolysis at 200.00 ¦Ìg/ml,  100% haemolysis at 400.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20906	HHIIGGLFSAGKAIHRLIRRRRR	23	dN2	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=512 ¦Ìg/ml; MBC=512 ¦Ìg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=512 ¦Ìg/ml; MBC>512 ¦Ìg/ml);##Fungi: Candida albicans (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml)	"[Ref.29040295] 5% haemolysis at 12.50 ¦Ìg/ml,  5% haemolysis at 25.00 ¦Ìg/ml,  20% haemolysis at 50.00 ¦Ìg/ml,  65% haemolysis at 100.00 ¦Ìg/ml,  90% haemolysis at 200.00 ¦Ìg/ml,  100% haemolysis at 400.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20907	IIGGLFSAGKAIHRLIRRRRR	21	dN4	No entry found	Derived from TP4	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	Not found	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29040295] Gram-positive bacteria: Staphylococcus aureus (MIC=128 ¦Ìg/ml; MBC=128 ¦Ìg/ml), Methicillin-resistant Staphylococcus aureus (MIC=64 ¦Ìg/ml; MBC=256 ¦Ìg/ml);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=256 ¦Ìg/ml; MBC>512 ¦Ìg/ml);##Fungi: Candida albicans (MIC=64 ¦Ìg/ml; MBC=128 ¦Ìg/ml)"	"[Ref.29040295] 10% haemolysis haemolysis at 12.50 ¦Ìg/ml,  12% haemolysis haemolysis at 25.00 ¦Ìg/ml,  20% haemolysis haemolysis at 50.00 ¦Ìg/ml,  35% haemolysis haemolysis at 100.00 ¦Ìg/ml,  75% haemolysis haemolysis at 200.00 ¦Ìg/ml,  100% haemolysis haemolysis at 400.00 ¦Ìg/ml,  100% haemolysis haemolysis at 800.00 ¦Ìg/ml against mouse red blood cells"	Linear	Free	Free	None	L	[Ref.29040295] No cytotoxicity information found	Not found	29040295	PLoS One. 2017 Oct 17;12(10):e0186442. 	"Chang TW, Wei SY, Wang SH, Wei HM, Wang YJ, Wang CF, Chen C, Liao YD."	"Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4."
DRAMP20911	CMSTRGDQARKICE	14	Sm-AMP-X2	U4N938	Belongs to the 	sm-amp-x	Stellaria media (Common chickweed) 	"Antimicrobial, Antifungal"	protein level	Not found	Not found	None	Function: The mature peptide has antifungal activities	"[Ref.24081691] Fungus: Alternaria alternata(IC50>32.0¦ÌM), Aspergillus niger(IC50=16.9¡À1.9¦ÌM), Bipolaris sorokiniana(IC50>32.0¦ÌM), Botrytis cinerea(IC50>32.0¦ÌM), Fusarium oxysporum(IC50=25.0¡À3.0¦ÌM), Fusarium solani(IC50=22.5¡À3.1¦ÌM), Phytophthora infestans(IC50>32.0¦ÌM), Pythium ultimum(IC50>32.0¦ÌM)."	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic	Free	Free	Disulfide bond between Cys1 and Cys13	L	[Ref.24081691] No cytotoxicity information found	Not found	24081691	Plant Mol Biol. 2014 Jan;84(1-2):189-202. doi: 10.1007/s11103-013-0127-z. Epub 2013 Oct 1.	"Slavokhotova AA, Rogozhin EA, Musolyamov AK, Andreev YA, Oparin PB, Berkut AA, Vassilevski AA, Egorov TA, Grishin EV, Odintsova TI."	Novel antifungal 
DRAMP20933	FFSLIPSLVGGLISAFK	17	Stigmurin	No entry found	Derived from scorpion venom peptide	Not found	Tityus stigmurus	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal, Antiparasitic, Antiproliferative"	Transcript level	Alpha helix 	Not found	None	Function: Antibacterial activity against the Gram-positive bacteria. Antifungal activity against yeasts.Antiparasitic Activity against epimastigote forms of Trypanosoma cruzi. Antiproliferative Activity against HeLa cells.	"[Ref.29670004] Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=9.38 ¦ÌM), Staphylococcus epidermidis ATCC 122225 (MIC=9.38 ¦ÌM);##yeasts: Candida albicans ATCC 90028 (MIC=37.5 ¦ÌM);##Stigmurin inhibit 90% of the epimastigote forms of Trypanosoma cruzi growth at 25 ?M;##HeLa cell line: IC50=7.98 ¦ÌM"	"[Ref.29670004]Hemolysis 0% at 1.17 ¦ÌM, hemolysis 1% at 2.34 ¦ÌM, hemolysis 1% at 4.69 ¦ÌM, hemolysis 0% at 9.38 ¦ÌM, hemolysis 1% at 18.75 ¦ÌM, hemolysis 1% at 37.50 ¦ÌM, hemolysis 3% at 75.00 ¦ÌM against human red blood cell"	Linear	Free	Amidation	None	L	"[Ref.29670004] The cell viability of HeLa cell lines is 56%, 66%, 66%, 81%, 78%, 66% and 30% at peptide concentrations of 2, 4, 8, 10, 15,  20 and 40 ¦ÌM. ##The cell viability of 3T3 cell lines is 81%, 63%, 51%, 29%, 27%, 19% and 15% at peptide concentra"	Not found	29670004	Toxins (Basel). 2018 Apr 18;10(4). pii: E161.	"Parente AMS, Daniele-Silva A, Furtado AA, Melo MA, Lacerda AF, Queiroz M, Moreno C, Santos E, Rocha HAO, Barbosa EG, Carvalho E, Silva-J¨²nior AA, Silva MS, Fernandes-Pedrosa MF."	"Analogs of the Scorpion Venom Peptide Stigmurin: Structural Assessment, Toxicity, and Increased Antimicrobial Activity."
DRAMP20935	GFGMALKLLKKVL	13	"Macropin 1(solitary bee, insects, animals)"	C0HL98	Not found	Not found	Macropis fulvipes (Solitary bee) (Megilla fulvipes)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	"Alpha helix,random coil"	Not found	None	"[Ref.24616110] Antimicrobial peptide active against Gram-positive bacteria like B.subtilis, S.aureus and L.monocytogenes as well as against Gram-negative bacteria like E.coli and P.aeruginosa with minimum inhibitory concentrations (MIC) between 1.3 ?M and 35 ?M.Active against fungus C.albicans (MIC=6.3 ?M).Has little hemolytic activity . Adopts an alpha-helical structure in a membrane mimic environment. [Ref.29185466] Acts by disrupting membranes and bacterial cell wall structures.Binds to peptidoglycan and lipopolysaccharide (LPS)"	"[Ref.24616110] Gram-negative bacteria: Escherichia coli(MIC=3.0 ¦ÌM), Pseudomonas aeruginosa(MIC=35.0 ¦ÌM);## Gram-positive bacteria: Bacillus subtilis (MIC=1.3 ¦ÌM), Staphylococcus aureus(MIC=3.7 ¦ÌM);## Fungus: Candida albicans (MIC=6.3 ¦ÌM). ##[Ref.29185466]Gram-positive bacteria:Staphylococcus aureus ATCC 25923 (MIC=3.13 ¦ÌM), Staphylococcus aureus ATCC 29213 (MIC=3.13 ¦ÌM), Listeria monocytogenes KCTC 3710 (MIC=25 ¦ÌM);##Gram-negative bacteria: Pseudomonas aeruginosa ATCC 27853 (MIC=6.25 ¦ÌM), Pseudomonas aeruginosa ATCC 15692 (MIC=6.25 ¦ÌM), Escherichia coli ATCC 25922 (MIC=6.25 ¦ÌM)"	"[Ref.24616110] LC50=160 ¦ÌM against human red blood cells. ##[Ref.29185466]5% hemolysis at 25 ¦ÌM against red blood cells, 93% hemolysis at 50 ¦ÌM against red blood cells"	Linear	Free	Amidation	None	L	"[Ref.29185466] In HaCaT cells, Macropin produced cell survival rates of 82% and 41% at  peptide concentrations of 25 and 50 ¦ÌM.## In Raw cells, Macropin produce cell survival rates of 41% and 0% at peptide concentrations of 25 and 50 ¦ÌM."	Not found	24616110##29185466	J Pept Sci. 2014 Jun;20(6):375-84. doi: 10.1002/psc.2625. Epub 2014 Mar 11.## Sci Rep. 2017 Nov 29;7(1):16580. doi: 10.1038/s41598-017-16784-6.	"Monincov¨¢ L, Veverka V, Slaninov¨¢ J, Bud¨§?¨ªnsk? M, Fu?¨ªk V, Bedn¨¢rov¨¢ L, Straka J, Ce?ovsk? V.## Ko SJ, Kim MK, Bang JK, Seo CH, Luchian T, Park Y."	"Structure-activity study of macropin, a novel antimicrobial peptide from the venom of solitary bee Macropis fulvipes (Hymenoptera: Melittidae).## Macropis fulvipes Venom component Macropin Exerts its Antibacterial and Anti-Biofilm Properties by Damaging the Plasma Membranes of Drug Resistant Bacteria."
DRAMP20941	FVPWFSKFLKRIL	13	"[Pro3,DLeu9]TL(8) (Temporin L peptide derivative)"	No entry found	Derived from Temporin L	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	The analogues bearing a D residue showed a reduction in the percentage of helicity compared to the corresponding L analogues in the MMs 	None	"Function: Antimicrobial activity against the Gram-negative bacteria, Gram-positive bacteria and Fungi. The position 9 of [Pro3,DLeu9]TL(8) is D-Leucine, L-Lysine replace L-Proline at the position 10 on the  peptide [Pro3,DLeu9]TL(2)."	"[Ref.28863356] Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=3.125¦ÌM), Staphylococcus aureus Cowan I (MIC=6.25¦ÌM), Staphylococcus epidermidis ATCC 12228 (MIC=3.125¦ÌM);##Gram-negative bacteria: Acinetobacter baumannii ATCC 19606 (MIC=3.125¦ÌM), Escherichia coli D21 (MIC=12.5¦ÌM), Pseudomonas syringae pv tabaci 1918 (MIC=6.25¦ÌM), Pseudomonas aeruginosa ATCC 2785 (MIC=12.5¦ÌM);##Yeasts: Candida albicans ATCC 10231 (MIC=1.56¦ÌM), Candida crusei ATCC 6258 (MIC=1.56¦ÌM)"	"[Ref.28863356]49.30 ¡À 2.88% cytotoxic effect at 12.5 ¦ÌM, 66.86 ¡À 2.81%  cytotoxic effect at 25 ¦ÌM, 96.79 ¡À 1.24% cytotoxic effect at 50 ¦ÌM on HaCaT cells."	Linear	Free	Amidation	None	Mixed (D-Leu9)	"[Ref.28863356] The cytotoxic effect is 49.30¡À2.88%, 66.86¡À2.81% and 96.79¡À1.24% at peptide concentrations of 12.5, 25 and 50 ¦ÌM"	Not found	28863356	Eur J Med Chem. 2017 Oct 20;139:750-761.	"Merlino F, Carotenuto A, Casciaro B, MartorMerlino F, Carotenuto A, Casciaro B, Martora F, Loffredo MR, Di Grazia A, Yousif AM, Brancaccio D, Palomba L, Novellino E, Galdiero M, Iovene MR, Mangoni ML, Grieco P."	"Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities"
DRAMP20942	FVPWFSKFLKRIL	13	"[Pro3,DLeu9]TL(9) (Temporin L peptide derivative)"	No entry found	Derived from Temporin L	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	The analogues bearing a D residue showed a reduction in the percentage of helicity compared to the corresponding L analogues in the MMs 	None	"Function: Antimicrobial activity against the Gram-negative bacteria, Gram-positive bacteria and Fungi. The position 9 of [Pro3,DLeu9]TL(9) is D-Leucine, D-Lysine replace L-Proline at the position 10 on the  peptide [Pro3,DLeu9]TL(2)."	"[Ref.28863356] Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=3.125 ¦ÌM), Staphylococcus aureus Cowan I (MIC=12.5 ¦ÌM), Staphylococcus epidermidis ATCC 12228 (MIC=3.125 ¦ÌM);##Gram-negative bacteria: Acinetobacter baumannii ATCC 19606 (MIC=6.25 ¦ÌM), Escherichia coli D21 (MIC=12.5 ¦ÌM), Pseudomonas syringae pv tabaci 1918 (MIC=12.5 ¦ÌM), Pseudomonas aeruginosa ATCC 2785 (MIC=12.5 ¦ÌM);##Yeasts: Candida albicans ATCC 10231 (MIC=1.56 ¦ÌM), Candida crusei ATCC 6258 (MIC=1.56 ¦ÌM)"	"[Ref.28863356]7¡À4% hemolysis at 50 ¦ÌM, 5¡À3% hemolysis at 25 ¦ÌM, 5¡À2% hemolysis at 12.5 ¦ÌM, 1¡À2% hemolysis at 6.25 ¦ÌM, 0¡À1%  hemolysis at 3.125 ¦ÌM against human red blood cells. ##28.22 ¡À 3.52%  cytotoxic effect at 25 ¦ÌM, 87.9 ¡À 1.07% cytotoxic effect at 50 ¦ÌM on HaCaT cells."	Linear	Free	Amidation	None	"Mixed (D-Leu9, D-Lys10)"	"[Ref.28863356] The cytotoxic effect is 0%, 28.22¡À3.52% and 87.9¡À1.07% at 12.5, 25 and 50 ¦ÌM"	Not found	28863356	Eur J Med Chem. 2017 Oct 20;139:750-761.	"Merlino F, Carotenuto A, Casciaro B, Martora F, Loffredo MR, Di Grazia A, Yousif AM, Brancaccio D, Palomba L, Novellino E, Galdiero M, Iovene MR, Mangoni ML, Grieco P."	"Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities"
DRAMP20943	FVPWFSKFLWRIL	13	"[Pro3,DLeu9]TL(10) (Temporin L peptide derivative)"	No entry found	Derived from Temporin L	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	A distorted (type IV) 	None	"Function: Antimicrobial activity against the Gram-negative bacteria, Gram-positive bacteria and Fungi. The position 9 of [Pro3,DLeu9]TL(8) is D-Leucine, L-Tryptophan replace L-Proline at the position 10 on the  peptide [Pro3,DLeu9]TL(2)."	"[Ref.28863356] Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=1.56 ¦ÌM), Staphylococcus aureus Cowan I (MIC=3.125 ¦ÌM), Staphylococcus epidermidis ATCC 12228 (MIC=1.56 ¦ÌM);##Gram-negative bacteria: Acinetobacter baumannii ATCC 19606 (MIC=3.125 ¦ÌM), Escherichia coli D21 (MIC=25 ¦ÌM), Pseudomonas syringae pv tabaci 1918 (MIC=1.56 ¦ÌM);##Yeasts: Candida albicans ATCC 10231 (MIC=3.125 ¦ÌM), Candida crusei ATCC 6258 (MIC=3.125 ¦ÌM)"	"[Ref.28863356]37¡À1% hemolysis at 50¦ÌM, 20¡À3% hemolysis at 25¦ÌM, 7¡À1% hemolysis at 12.5¦ÌM, 4¡À2% hemolysis at 6.25¦ÌM, 2¡À1%  hemolysis at 3.125¦ÌM against human red blood cells.##32.1 ¡À 2.21%  cytotoxic effect at 25¦ÌM, 89.3 ¡À 0.8% cytotoxic effect at 50 ¦ÌM on HaCaT cells."	Linear	Free	Amidation	None	Mixed (D-Leu9)	"[Ref.28863356] The cytotoxic effect is 0%, 32.1¡À2.21% and 89.3¡À0.8% at  12.5, 25 and 50 ¦ÌM"	Not found	28863356	Eur J Med Chem. 2017 Oct 20;139:750-761.	"Merlino F, Carotenuto A, Casciaro B, Martora F, Loffredo MR, Di Grazia A, Yousif AM, Brancaccio D, Palomba L, Novellino E, Galdiero M, Iovene MR, Mangoni ML, Grieco P."	"Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities"
DRAMP20944	FVPWFSKFLWRIL	13	"[Pro3,DLeu9]TL(11) (Temporin L peptide derivative)"	No entry found	Derived from Temporin L	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix	The analogues bearing a D residue showed a reduction in the percentage of helicity compared to the corresponding L analogues in the MMs 	None	"Function: Antimicrobial activity against the Gram-negative bacteria, Gram-positive bacteria and Fungi. The position 9 of [Pro3,DLeu9]TL(10) is D-Leucine, D-Tryptophan replace L-Proline at the position 10 on the  peptide [Pro3,DLeu9]TL(2)."	"[Ref.28863356] Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=3.125¦ÌM), Staphylococcus aureus Cowan I (MIC=3.125¦ÌM), Staphylococcus epidermidis ATCC 12228 (MIC=1.56¦ÌM);##Gram-negative bacteria: Acinetobacter baumannii ATCC 19606 (MIC=3.125¦ÌM), Escherichia coli D21 (MIC=25¦ÌM), Pseudomonas syringae pv tabaci 1918 (MIC=3.125¦ÌM), Pseudomonas aeruginosa ATCC 2785 (MIC=50¦ÌM);##Yeasts: Candida albicans ATCC 10231 (MIC=3.125¦ÌM),Candida crusei ATCC 6258 (MIC=3.125¦ÌM)"	"[Ref.28863356]19.21 ¡À 1.44% cytotoxic effect at 12.5¦ÌM, 35.34 ¡À 5.99%  cytotoxic effect at 25¦ÌM, 96.77 ¡À 0.81% cytotoxic effect at 50 ¦ÌM on HaCaT cells."	Linear	Free	Amidation	None	"Mixed (D-Leu9, D-Trp10)"	"[Ref.28863356] The cytotoxic effect is 19.21¡À1.44%, 35.34¡À5.99% and 96.77¡À0.81% at 12.5, 25 and 50 ¦ÌM"	Not found	28863356	Eur J Med Chem. 2017 Oct 20;139:750-761.	"Merlino F, Carotenuto A, Casciaro B, Martora F, Loffredo MR, Di Grazia A, Yousif AM, Brancaccio D, Palomba L, Novellino E, Galdiero M, Iovene MR, Mangoni ML, Grieco P."	"Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities"
DRAMP20955	LGDFFRKSKEKIGKEFKRIVQRIKDFLRNLAKRHHGYKRKFH	42	L31-P113	No entry found	Derived from LL-37	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix 	The peptide adopts a conformational structure with 80 % alpha helix.	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	[Ref.29859288] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=25?¡À?0 ¦Ìg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=16.6?¡À?7.2 ¦ÌM);##Fungi: Candida albicans ATCC 90028 (MIC=166.6?¡À?57.7 ¦Ìg/mL)	[Ref.29859288] Hemolysis 12.0?¡À?0.7% at 500 ¦Ìg/ml against human red blood cells	Linear	Free	Free	None	L	[Ref.29859288] No cytotoxicity information found	Not found	29859288	Gene. 2018 May 30. pii: S0378-1119(18)30617-6.	"Wanmakok M, Orrapin S, Intorasoot A, Intorasoot S."	Expression in Escherichia coli of novel recombinant hybrid antimicrobial peptide AL32-P113 with enhanced antimicrobial activity in vitro.
DRAMP20956	ALGDFFRKSKEKIGKEFKRIVQRIKDFLRNLAKRHHGYKRKFHLEY	46	AL32-P113	No entry found	Derived from LL-37 and Hst-5	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic	Alpha helix 	The peptide adopts a conformational structure with 81 % alpha helix.	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity.	"[Ref.29859288] Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=66.6?¡À?28.8 ¦Ìg/mL);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=41.6?¡À?14.4 ¦ÌM), Extended-spectrum beta-lactamase producing Escherichia coli (MIC=41.6?¡À?14.4 ¦Ìg/mL), New Delhi metallo-bata-lactamase-1 producing Acinetobacter baumannii  (MIC=20.8?¡À?7.2 ¦Ìg/mL);##Fungi: Candida albicans ATCC 90028 (MIC=166.6?¡À?57.7 ¦Ìg/mL)"	[Ref.29859288] Hemolysis 10.4?¡À?2.2% at 500 ¦Ìg/ml against human red blood cells	Linear	Free	Free	None	L	[Ref.29859288] No cytotoxicity information found	Not found	29859288	Gene. 2018 May 30. pii: S0378-1119(18)30617-6.	"Wanmakok M, Orrapin S, Intorasoot A, Intorasoot S."	Expression in Escherichia coli of novel recombinant hybrid antimicrobial peptide AL32-P113 with enhanced antimicrobial activity in vitro.
DRAMP20957	FFSLIPKLVKGLISAFK	17	StigA6	No entry found	Derived from scorpion venom peptide	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiparasitic, Antiproliferative"	Synthetic	Alpha helix 	"The peptide adopts helical conformation with some random structure at the N- and C-terminals. In sodium phosphate buffer (PBS) and water they have a predominantly random structure, but in 20 mM sodium dodecyl sulfate (SDS) and 2,2,2-trifluoroethanol (TFE) they have a typical alpha-helix structure."	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity against yeasts.Antiparasitic Activity against epimastigote forms of Trypanosoma cruzi. Antiproliferative Activity against HeLa cells.	"[Ref.29670004] Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=2.34 ¦ÌM), Staphylococcus epidermidis ATCC 122225 (MIC=9.38 ¦ÌM), Enterococcus faecalis ATCC 4028 (MIC=1.17 ¦ÌM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=4.69 ¦ÌM), Enterobacter cloacae ATCC 13047 (MIC=18.75 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC=9.38 ¦ÌM);##yeasts: Candida albicans ATCC 90028 (MIC=9.38 ¦ÌM), Candida krusei ATCC 6258 (MIC=37.5 ¦ÌM), Candida glabrata ATCC 90030 (MIC=18.75 ¦ÌM);##StigA6 inhibit 100% of the epimastigote forms of Trypanosoma cruzi growth at 2.5 ?M;##HeLa cell line: IC50=14.01 ?M"	"[Ref.29670004] Hemolysis 0% at 1.17 ¦ÌM, hemolysis 2% at 2.34 ¦ÌM, hemolysis 15% at 4.69 ¦ÌM, hemolysis 27% at 9.38 ¦ÌM, hemolysis 30% at 18.75 ¦ÌM, hemolysis 30% at 37.50 ¦ÌM, hemolysis 27% at 75.00 ¦ÌM against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.29670004] The cell viability of HeLa cell lines is 19%, 15%, 11%, 29%, 9%, 13% and 8% at peptide concentrations of 2, 4, 8, 10, 15, 20 and 40 ¦ÌM.  ##The cell viability of 3T3 cell lines is 81%, 73%, 69%, 61%, 51%, 20% and 15% at peptide concentrati"	Not found	29670004	Toxins (Basel). 2018 Apr 18;10(4). pii: E161.	"Parente AMS, Daniele-Silva A, Furtado AA, Melo MA, Lacerda AF, Queiroz M, Moreno C, Santos E, Rocha HAO, Barbosa EG, Carvalho E, Silva-J¨²nior AA, Silva MS, Fernandes-Pedrosa MF."	"Analogs of the Scorpion Venom Peptide Stigmurin: Structural Assessment, Toxicity, and Increased Antimicrobial Activity."
DRAMP20958	FFKLIPKLVKGLISAFK	17	StigA16	No entry found	Derived from scorpion venom peptide	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiparasitic, Antiproliferative"	Synthetic	Alpha helix 	"The peptide adopts helical conformation with some random structure at the N- and C-terminals. In sodium phosphate buffer (PBS) and water they have a predominantly random structure, but in 20 mM sodium dodecyl sulfate (SDS) and 2,2,2-trifluoroethanol (TFE) they have a typical alpha-helix structure."	None	Function: Antibacterial activity against the Gram-positive and Gram-negative bacteria. Antifungal activity against yeasts.Antiparasitic Activity against epimastigote forms of Trypanosoma cruzi. Antiproliferative Activity against HeLa cells.	"[Ref.29670004] Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=2.34 ¦ÌM), Staphylococcus epidermidis ATCC 122225 (MIC=9.38 ¦ÌM), Enterococcus faecalis ATCC 4028 (MIC=1.17 ¦ÌM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2.34 ¦ÌM), Enterobacter cloacae ATCC 13047 (MIC=9.38 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC=1.17 ¦ÌM);##yeasts: Candida albicans ATCC 90028 (MIC=4.69 ¦ÌM), Candida krusei ATCC 6258 (MIC=9.38 ¦ÌM), Candida glabrata ATCC 90030 (MIC=9.38 ¦ÌM);##StigA16 inhibit 100% of the epimastigote forms of Trypanosoma cruzi growth at 2.5 ?M;##HeLa cell line: IC50=13.01 ?M"	"[Ref.29670004] Hemolysis 0% at 1.17 [Ref.29670004] Hemolysis 0% at 1.17 ¦ÌM, hemolysis 2% at 2.34 ¦ÌM, hemolysis 10% at 4.69 ¦ÌM, hemolysis 20% at 9.38 ¦ÌM, hemolysis 35% at 18.75 ¦ÌM, hemolysis 37% at 37.50 ¦ÌM, hemolysis 40% at 75.00 ¦ÌM against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.29670004] The cell viability of HeLa cell lines is 15%, 21%, 16%, 9%, 8%, 10% and 11% at peptide concentrations of 2, 4, 8, 10, 15, 20 and 40 ¦ÌM. ##The cell viability of 3T3 cell lines is 69%, 77%, 62%, 47%, 21%, 15% and 15% at peptide concentratio"	Not found	29670004	Toxins (Basel). 2018 Apr 18;10(4). pii: E161.	"Parente AMS, Daniele-Silva A, Furtado AA, Melo MA, Lacerda AF, Queiroz M, Moreno C, Santos E, Rocha HAO, Barbosa EG, Carvalho E, Silva-J¨²nior AA, Silva MS, Fernandes-Pedrosa MF."	"Analogs of the Scorpion Venom Peptide Stigmurin: Structural Assessment, Toxicity, and Increased Antimicrobial Activity."
DRAMP20965	MNKVKEWIKYLKSLFSM	17	"LPcin-YK3 (bovine cathelicidin, cattle, ruminant, mammals, animals)"	No entry found	Not found	Not found	Bovine Lactophoricin	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	"Random coil, alpha helix"	LPcin-YK3 peptide is a random coil in aqueous solution and forms an 	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans"	"[Ref.30021422] Gram-positive bacteria : Streptococcus mutans KCCM 40105 (MIC=1.25 ¦Ìg/ml), Propionibacteria acnes KCCM 41747 (MIC=1.25 ¦Ìg/ml), Staphylococcus aureus KCTC 1621 (MIC=0.62 ¦Ìg/ml);##Gram-negative bacteria : Porphyromonas gingvalis KCTC 5352 (MIC=0.62 ¦Ìg/ml), Escherichia coli KCCM 41290 (MIC=1.25 ¦Ìg/ml);##Fungi : Candida albicans KCTC 17712 (MIC=10.0 ¦Ìg/ml)"	[Ref.30021422] 0% hemolysis  at 40 ¦Ìg/ml against mouse red blood cell	Linear	Free	Free	None	L	[Ref.30021422] No cytotoxicity information found	Not found	30021422	J Microbiol Biotechnol.?2018 Aug 28;28(8):1299-1309. doi: 10.4014/jmb.1805.05001.	"Ji-Sun Kim,Ji-Ho Jeong, Jang-Hee Cho,Dong-Hee Lee and Yongae Kim"	Antimicrobial Activity of Antimicrobial Peptide LPcin-YK3 Derived from Bovine Lactophoricin
DRAMP20966	GLTRLFSVIK	10	"andricin B (Andrias davidianus, Amphibians, Animals)"	No entry found	Not found	Not found	Andrias davidianus	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Random coil	"The residues Lys and Arg possess the positive charge, and charge-induced folding may influence the structure."	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Saccharomyces cerevisiae, Aspergillus niger"	"[Ref.29130500]Gram-positive bacteria : Bacillus subtilis CICC 10034 (MIC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml;MBC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml), Staphylococcus aureus CICC10306 (MIC=16 ¦Ìg/ml, 16.7 ¦ÌMol/ml;MBC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml), Staphylococcus aureus CICC 10384 (MIC=16 ¦Ìg/ml, 16.7 ¦ÌMol/ml;MBC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml), Listeria innocua CICC 10417 (MIC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml;MBC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml);##Gram-negative bacteria : Escherichia coli CICC10293 (MIC=16 ¦Ìg/ml, 16.7 ¦ÌMol/ml;MBC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml), Pseudomonas aeruginosa CICC 21636 (MIC=8 ¦Ìg/ml, 8.3 ¦ÌMol/ml;MBC=16 ¦Ìg/ml, 16.7 ¦ÌMol/ml), Serratia marcescens ATCC 4112 (MIC=8 ¦Ìg/ml, 8.3 ¦ÌMol/ml;MBC=16 ¦Ìg/ml, 16.7 ¦ÌMol/ml), Enterobacter cloacae CICC 21539 (MIC=16 ¦Ìg/ml, 16.7 ¦ÌMol/ml;MBC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml), Salmonella paratyphi CICC 10437 (MIC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml;MBC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml);##Fungi : Aspergillus niger CICC 2124 (MIC=64 ¦Ìg/ml, 66.8 ¦ÌMol/ml;MBC=64 ¦Ìg/ml, 66.8 ¦ÌMol/ml), Candida albicans CICC 1965 (MIC=32 ¦Ìg/ml, 33.4 ¦ÌMol/ml;MBC=64 ¦Ìg/ml, 66.8 ¦ÌMol/ml), Saccharomyces cerevisiae CICC 1002 (MIC=64 ¦Ìg/ml, 66.8 ¦ÌMol/ml;MBC=64 ¦Ìg/ml, 66.8 ¦ÌMol/ml)"	"[Ref.29130500] 0% hemolysis  at 64 ¦Ìg/ml , 0.5% hemolysis at 128 ¦Ìg/ml , 2% hemolysis  at 256 ¦Ìg/ml , 13% hemolysis at 512 ¦Ìg/ml against human red blood cells"	Linear	Free	Free	None	L	[Ref.29130500] No cytotoxicity information found	Not found	29130500	Lett Appl Microbiol.?2018 Jan;66(1):38-43. doi: 10.1111/lam.12823.	"J. Pei, Z. Feng,T. Ren,H. Sun,H. Han,W. Jin,J. Dang and Y. Tao"	"Purifification, characterization and application of a novel antimicrobial peptide from Andrias davidianus blood"
DRAMP20969	KLLKHKLLVTLA	12	"HJH-1 (bovine cathelicidin, cattle, ruminant, mammals, animals)"	No entry found	Not found	Not found	Bovine	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans"	"[Ref.30110916]Gram-positive bacteria : Staphylococcus aureus ATCC29213 (MIC=25 ¦Ìg/ml), Clinical Staphylococcus aureus (MIC=25 ¦Ìg/ml), ;##Gram-negative bacteria : Escherichia coli ATCC25922 (MIC=12.5 ¦Ìg/ml), Clinical Escherichia coli (MIC=25 ¦Ìg/ml), Salmonella pullorum CVCC3533 (MIC=6.25 ¦Ìg/ml), Clinical Salmonella (MIC=6.25 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90029 (MIC=50 ¦Ìg/ml)"	"[Ref.30110916] 8% hemolysis at 50 ¦Ìg/ml , 12% hemolysis at 100 ¦Ìg/ml , 16% hemolysis at 200 ¦Ìg/ml , 17% hemolysis at 300 ¦Ìg/ml , 18% hemolysis at 400 ¦Ìg/ml against rabbit red blood cells"	Linear	Free	Free	None	L	[Ref.30110916] No cytotoxicity information found	Not found	30110916	Molecules. 2018 Aug 14;23(8). pii: E2026. doi: 10.3390/molecules23082026.	"Qing Wang, Yanzhao Xu, Mengmeng Dong, Bolin Hang, Yawei Sun, Lei Wang,Yongqiang Wang, Jianhe Hu, and Wenju Zhang "	"HJH-1, a Broad-Spectrum Antimicrobial Activity and Low Cytotoxicity Antimicrobial Peptide"
DRAMP20970	VNFKLLSHSLLVTLASHL	18	"P3 (bovine cathelicidin, cattle, ruminant, mammals, animals)"	P01966	Belongs to the globin family.	HBA	Bos taurus (Bovine)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans"	"[Ref.25753638] Gram-positive bacteria : Staphylococcus aureus ATCC29213 (MIC=25 ¦Ìg/ml), Clinical Staphylococcus aureus (MIC=12.5 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC25922 (MIC=12.5 ¦Ìg/ml), Clinical Escherichia coli (MIC=12.5 ¦Ìg/ml), Pseudomonas aeruginosa clinical strain (MIC=25 ¦Ìg/ml);##Fungi : Candida albicans Clinical strain (MIC=25 ¦Ìg/ml), Candida albicans ATCC 90029 (MIC=50 ¦Ìg/ml)"	"[Ref.25753638] 3% hemolysis at 50 ¦Ìg/ml , 5% hemolysis  at 100 ¦Ìg/ml , 7% hemolysis at 200 ¦Ìg/ml , 7.5% hemolysis at 300 ¦Ìg/ml , 8% hemolysis at 400 ¦Ìg/ml against human red blood cells"	Linear	Free	Free	None	L	"[Ref.25753638] The cell viability of HaCaT cell lines is 93% and 94% at peptide concentrations of 200 and 400 ¦Ìg/ml. In kumning mice, the LD50 of P3 is 160 mg/kg for i.p. injection, while the LD50 of PMB(served as a control) is 50 mg/kg. No mortality w"	Not found	25753638	Antimicrob Agents Chemother. 2015 May;59(5):2835-41. doi: 10.1128/AAC.04932-14.	"Qinghua Zhang, Yanzhao Xu, Qing Wang, Bolin Hang, Yawei Sun, Xiaoxiao Wei, Jianhe Hu"	Potential of Novel Antimicrobial Peptide P3 from Bovine Erythrocytes and Its Analogs To Disrupt Bacterial Membranes In Vitro and Display Activity against Drug-Resistant Bacteria in a Mouse Model
DRAMP20973	VRFKLLSHSLLVTLASHL	18	JH-2 (Derived from  P3)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans"	"[Ref.25753638] Gram-positive bacteria : Staphylococcus aureus ATCC29213 (MIC=12.5 ¦Ìg/ml), Clinical Staphylococcus aureus (MIC=6.25 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC25922 (MIC=6.25 ¦Ìg/ml), Clinical Escherichia coli (MIC=12.5 ¦Ìg/ml), Pseudomonas aeruginosa clinical strain (MIC=6.25 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90029 (MIC=25 ¦Ìg/ml), Candida albicans Clinical strain (MIC=25 ¦Ìg/ml)"	"[Ref.25753638] 2% hemolysis at 50 [Ref.25753638] 2% hemolysis at 50 ¦Ìg/ml , 2.5% hemolysis at 100 ¦Ìg/ml , 3.5% hemolysis at 200 ¦Ìg/ml , 4% hemolysis at 300 ¦Ìg/ml , 4% hemolysis at 400 ¦Ìg/ml against human red blood cells"	Linear	Free	Free	None	L	"[Ref.25753638] The cell viability of HaCaT cell lines is 88% and 84% at peptide concentrations of 200 and 400 ¦Ìg/ml. In Kunming mice, the LD50 of JH-2 is 133 mg/kg for i.p. injection, while the LD50 of PMB(served as a control) is 50 mg/kg. no mortality"	Not found	25753638	Antimicrob Agents Chemother. 2015 May;59(5):2835-41. doi: 10.1128/AAC.04932-14.	"Qinghua Zhang, Yanzhao Xu, Qing Wang, Bolin Hang, Yawei Sun, Xiaoxiao Wei, Jianhe Hu"	Potential of Novel Antimicrobial Peptide P3 from Bovine Erythrocytes and Its Analogs To Disrupt Bacterial Membranes In Vitro and Display Activity against Drug-Resistant Bacteria in a Mouse Model
DRAMP20974	RRFKLLSHSLLVTLASHL	18	JH-3 (Derived from  P3)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans"	"[Ref.25753638]Gram-positive bacteria : Staphylococcus aureus ATCC29213 (MIC=6.25 ¦Ìg/ml), Clinical Staphylococcus aureus (MIC=3.125 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC25922 (MIC=3.125 ¦Ìg/ml), Clinical Escherichia coli (MIC=3.125 ¦Ìg/ml), Pseudomonas aeruginosa clinical strain (MIC=6.25 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90029 (MIC=12.5 ¦Ìg/ml), Candida albicans Clinical strain (MIC=6.25 ¦Ìg/ml)"	"[Ref.25753638] 8% hemolysis at 50 ¦Ìg/ml , 13% hemolysis at 100 ¦Ìg/ml , 17% hemolysis at 200 ¦Ìg/ml , 18% hemolysis at 300 ¦Ìg/ml , 18.5% hemolysis at 400 ¦Ìg/ml against human red blood cells"	Linear	Free	Free	None	L	"[Ref.25753638] The cell viability of HaCaT cell lines is 86% and 86% at peptide concentrations of 200 and 400 ¦Ìg/ml. In Kunming mice, the LD50 of JH-3 is 180 mg/kg for i.p. injection, , while the LD50 of PMB(served as a control) is 50 mg/kg. No mortali"	Not found	25753638	Antimicrob Agents Chemother. 2015 May;59(5):2835-41. doi: 10.1128/AAC.04932-14.	"Qinghua Zhang, Yanzhao Xu, Qing Wang, Bolin Hang, Yawei Sun, Xiaoxiao Wei, Jianhe Hu"	Potential of Novel Antimicrobial Peptide P3 from Bovine Erythrocytes and Its Analogs To Disrupt Bacterial Membranes In Vitro and Display Activity against Drug-Resistant Bacteria in a Mouse Model
DRAMP20994	GLLKFIKKLL	10	anoplin analog 4	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida parapsilosis"	"[Ref.27862650]Gram-positive bacteria : Mycobacteria smegmatis mc2 155 (MIC=15 ¦Ìg/ml), Bacillus subtilis DELTA (MIC=30 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli DH5a (MIC=300 ¦Ìg/ml), Zymomonas mobilis 10988 (MIC=7 ¦Ìg/ml);##Fungi : Candida parapsilosis (MIC=40 ¦Ìg/ml)"	"[Ref.27862650]0% hemolysis at 55¦Ìg/ml , 7% hemolysis at 100¦Ìg/ml , 17% hemolysis at 200¦Ìg/ml , 24% hemolysis at 300 ¦Ìg/ml , 33% hemolysis at 400¦Ìg/ml , 35% hemolysis at 500 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.27862650] No cytotoxicity information found	Not found	27862650	J Pept Sci. 2016 Nov;22(11-12):731-736. doi: 10.1002/psc.2939.	"Kostas Chionis, Dimitrios Krikorian, Anna-Irini Koukkou, Maria Sakarellos-Daitsiotis and Eugenia Panou-Pomonis"	Synthesis and biological activity of lipophilic analogs of the cationic antimicrobial active peptide anoplin
DRAMP20995	KLLKFIKKLL	10	anoplin analog 5	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida parapsilosis"	"[Ref.27862650]Gram-positive bacteria : Mycobacteria smegmatis mc2 155 (MIC=15 ¦Ìg/ml), Bacillus subtilis DELTA (MIC=40 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli DH5a (MIC=400 ¦Ìg/ml), Zymomonas mobilis 10988 (MIC=10 ¦Ìg/ml);##Fungi : Candida parapsilosis (MIC=30 ¦Ìg/ml)"	"[Ref.27862650]0% hemolysis at 100 ¦Ìg/ml , 4% hemolysis at 200 ¦Ìg/ml , 11% hemolysis at 300 ¦Ìg/ml , 13% hemolysis at 400 ¦Ìg/ml , 15% hemolysis at 500 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.27862650] No cytotoxicity information found	Not found	27862650	J Pept Sci. 2016 Nov;22(11-12):731-736. doi: 10.1002/psc.2939.	"Kostas Chionis, Dimitrios Krikorian, Anna-Irini Koukkou, Maria Sakarellos-Daitsiotis and Eugenia Panou-Pomonis"	Synthesis and biological activity of lipophilic analogs of the cationic antimicrobial active peptide anoplin
DRAMP20996	RLLKFIKKLL	10	anoplin analog 6	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida parapsilosis"	"[Ref.27862650]Gram-positive bacteria : Mycobacteria smegmatis mc2 155 (MIC=20 ¦Ìg/ml), Bacillus subtilis DELTA (MIC=40 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli DH5a (MIC=400 ¦Ìg/ml), Zymomonas mobilis 10988 (MIC=10 ¦Ìg/ml);##Fungi : Candida parapsilosis (MIC=30 ¦Ìg/ml)"	"[Ref.27862650]0% hemolysis at 300 ¦Ìg/ml , 3% hemolysis at 400 ¦Ìg/ml , 12% hemolysis at 500 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.27862650] No cytotoxicity information found	Not found	27862650	J Pept Sci. 2016 Nov;22(11-12):731-736. doi: 10.1002/psc.2939.	"Kostas Chionis, Dimitrios Krikorian, Anna-Irini Koukkou, Maria Sakarellos-Daitsiotis and Eugenia Panou-Pomonis"	Synthesis and biological activity of lipophilic analogs of the cationic antimicrobial active peptide anoplin
DRAMP21000	GCRRLCYKQRCVTYCRGR	18	cGm (Derived from Gm)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28741926]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=32 ¦ÌM);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=4 ¦ÌM), Escherichia coli CGSC 5167 (MIC=0.06 ¦ÌM), Klebsiella pneumoniae ATCC 700603 (MIC=4-8 ¦ÌM), Acinetobacter baumannii ATCC 19606 (MIC=1-2 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC=1-4 ¦ÌM), Helicobacter pylori ATCC 43504 (MIC= ¦ÌM);##Fungi : Candida albicans ATCC 90028 (MIC=4-8 ¦ÌM), Cryptococcus neoformans ATCC 208821 (MIC=0.5-1 ¦ÌM)"	"[Ref.28741926] 5% hemolysis at 0.03 ¦ÌM , 0% hemolysis at 1.1 ¦ÌM , 10% hemolysis at 17 ¦ÌM , 50% hemolysis at 100¦ÌM against human red blood cells"	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bond between Cys2 and Cys15,Cys6 and Cys11."	L	"[Ref.28741926] CC50 = 39.8 ¡À 1.0 ¦ÌM against CRL-1739, CC50 = 2.9 ¡À 0.1 ¦ÌM against MM96L, CC50 = 71.7 ¡À 9.2 ¦ÌM against HFF-1, CC50 > 64 ¦ÌM against HeLa, CC50 = 15.3 ¡À 1.4 ¦ÌM against MCF-7, CC50 = 2.7 ¡À 0.1 ¦ÌM against K-562, CC50 = 12.7 ¡À 1.1 ¦ÌM PBMCs."	Not found	28741926	ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459.?	"Sonia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval,Aurelie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan,Yen-Hua Huang, and David J. Craik"	Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties
DRAMP21004	GCRRLCWRQRCVTWCRGR	18	"[Y7W, K8R, Y14W]cGm (Derived from Gm) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria	[Ref.28741926]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=16 ¦ÌM);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=1 ¦ÌM)	[Ref.28741926] 42-49.8% hemolysis at 64 ¦ÌM against human red blood cells	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bonds between Cys2 and Cys15, Cys6 and Cys11."	L	"[Ref.28741926] CC50 = 31.6 ¡À 1.3 ¦ÌM against CRL-1739, CC50 = 5.4 ¡À 0.3 ¦ÌM against MM96L, CC50 = 31.3 ¡À 2.6 ¦ÌM against HFF-1, CC50 = 41.0 ¡À 4.2 ¦ÌM against HeLa, CC50 = 15.1 ¡À 1.4 ¦ÌM against MCF-7, CC50 = 3.9 ¡À 0.1 ¦ÌM against K-562."	Not found	28741926	ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459.?	"Sonia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval,Aurelie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan,Yen-Hua Huang, and David J. Craik"	Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties
DRAMP21005	GCRALCYKQRCVTYCRGA	18	"[R4A, R18A]cGm (Derived from Gm) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28741926]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=32 ¦ÌM);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=8 ¦ÌM), Escherichia coli CGSC 5167 (MIC=0.5-1 ¦ÌM), Klebsiella pneumoniae ATCC 700603 (MIC=32 ¦ÌM), Acinetobacter baumannii ATCC 19606 (MIC=8-16 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC=8 ¦ÌM), Helicobacter pylori ATCC 43504 (MIC>80 ¦ÌM);##Fungi : Candida albicans ATCC 90028 (MIC=32 ¦ÌM), Cryptococcus neoformans ATCC 208821 (MIC=8-16 ¦ÌM)"	"[Ref.28741926] 0% hemolysis at 17 ¦ÌM , 3% hemolysis at 35 ¦ÌM , 30-48.6% hemolysis at 64 ¦ÌM , 40% hemolysis at 100 ¦ÌM against human red blood cells"	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bonds between Cys2 and Cys15, Cys6 and Cys11."	L	"[Ref.28741926] CC50 > 64 ¦ÌM against CRL-1739, CC50 = 10.3 ¡À 1.1 ¦ÌM against MM96L, CC50 = 51.2 ¡À 4.0 ¦ÌM against HFF-1, CC50 > 64 ¦ÌM against HeLa, CC50 = 48.4 ¡À 0.7 ¦ÌM against MCF-7, CC50 = 11.5 ¡À 0.6 ¦ÌM against K-562, CC50 = 34.1 ¡À 3.9 ¦ÌM against HL-60;CC50=30.8 ¡À 2.5¦ÌM against PBMCs."	Not found	28741926	ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459.?	"Sonia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval,Aurelie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan,Yen-Hua Huang, and David J. Craik"	Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties
DRAMP21006	KCRRLCYRQRCVTYCRGR	18	"[G1K, K8R]cGm (Derived from Gm) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28741926]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=2 ¦ÌM);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=0.5-1 ¦ÌM), Escherichia coli CGSC 5167 (MIC<0.015 ¦ÌM), Klebsiella pneumoniae ATCC 700603 (MIC=8 ¦ÌM), Acinetobacter baumannii ATCC 19606 (MIC=1-2 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC<0.25 ¦ÌM), Helicobacter pylori ATCC 43504 (MIC>80 ¦ÌM);##Fungi : Candida albicans ATCC 90028 (MIC=2 ¦ÌM), Cryptococcus neoformans ATCC 208821 (MIC=0.125-0.25 ¦ÌM)"	"[Ref.28741926] 0% hemolysis at 0.5 ¦ÌM , 2.5% hemolysis at 0.6 ¦ÌM , 20% hemolysis at 8 ¦ÌM , 43.3-56.9% hemolysis at 64 ¦ÌM , 50% hemolysis at 100 ¦ÌM against human red blood cells"	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bonds between Cys2 and Cys15, Cys6 and Cys11."	L	"[Ref.28741926] CC50 = 19.5 ¡À 0.5 ¦ÌM against CRL-1739, CC50 = 1.7 ¡À 0.1 ¦ÌM against MM96L, CC50 = 9.0 ¡À 0.5 ¦ÌM against HFF-1, CC50 = 44.2 ¡À 2.2¦ÌM against HeLa, CC50 = 6.7 ¡À 0.7 ¦ÌM against MCF-7, CC50 = 2.1 ¡À 0.2 ¦ÌM against K-562, CC50 = 9.0 ¡À 1.1¦ÌM against HL-60;CC50=5.1 ¡À 0.3¦ÌM against PBMCs."	Not found	28741926	ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459.?	"Sonia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval,Aurelie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan,Yen-Hua Huang, and David J. Craik"	Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties
DRAMP21007	GURRLUYKQRUVTYURGR	18	[C/U]cGm (Derived from Gm) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28741926]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=16 ¦ÌM);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=4-8 ¦ÌM), Escherichia coli CGSC 5167 (MIC=0.03-0.06 ¦ÌM), Klebsiella pneumoniae ATCC 700603 (MIC=8-16 ¦ÌM), Acinetobacter baumannii ATCC 19606 (MIC=4 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC=2-4 ¦ÌM), Helicobacter pylori ATCC 43504 (MIC>80 ¦ÌM);##Fungi : Candida albicans ATCC 90028 (MIC=4-8 ¦ÌM), Cryptococcus neoformans ATCC 208821 (MIC=0.5-1 ¦ÌM)"	[Ref.28741926] 32.3-33.3% hemolysis at 64 ¦ÌM against human red blood cells	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bonds between SeCys2 and SeCys15, SeCys6 and SeCys11. The 'U' in sequence is SelenoCys."	L	"[Ref.28741926] CC50 = 51.0 ¡À 4.6 ¦ÌM against CRL-1739, CC50 = 4.6 ¡À 0.2 ¦ÌM against MM96L, CC50 = 15.6 ¡À 3.6 ¦ÌM against HFF-1, CC50 > 64 ¦ÌM against HeLa, CC50 = 37.5 ¡À 3.3 ¦ÌM against MCF-7, CC50 = 1.4 ¡À 0.2 ¦ÌM against K-562, CC50 = 38.5 ¡À 4.8 ¦ÌM against HL-60;CC50=15.5 ¡À 0.8¦ÌM against PBMCs."	Not found	28741926	ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459.?	"Sonia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval,Aurelie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan,Yen-Hua Huang, and David J. Craik"	Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties
DRAMP21009	GCRRLCYKQRCVTYCRGpPR	20	[D-P L-P]cGm (Derived from Gm) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28741926]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=16 ¦ÌM);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=4 ¦ÌM), Klebsiella pneumoniae ATCC 700603 (MIC=1-4 ¦ÌM), Acinetobacter baumannii ATCC 19606 (MIC=1-4 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC=4 ¦ÌM);##Fungi : Candida albicans ATCC 90028 (MIC=8 ¦ÌM), Cryptococcus neoformans ATCC 208821 (MIC=0.5-1 ¦ÌM)"	[Ref.28741926] 41.5-44.9% hemolysis at 64 ¦ÌM against human red blood cells	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bonds between Cys2 and Cys15, Cys6 and Cys11."	L	"[Ref.28741926] CC50 = 22.5 ¡À 3.3 ¦ÌM against CRL-1739, CC50 = 3.0 ¡À 0.1 ¦ÌM against MM96L, CC50 = 14.9 ¡À 0.8 ¦ÌM against HFF-1, CC50 = 51.5 ¡À 3.9 ¦ÌM against HeLa, CC50 = 3.9 ¡À 0.2 ¦ÌM against K-562, CC50 = 14.1 ¡À 0.9 ¦ÌM against PBMCs"	Not found	28741926	ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459.?	"Sonia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval,Aurelie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan,Yen-Hua Huang, and David J. Craik"	Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties
DRAMP21010	KCRRYCYRQRCVTYCRGR	18	"[G1K, L5Y, K8R]cGm (Derived from Gm) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28741926]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=8 ¦ÌM);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=0.5-1 ¦ÌM), Klebsiella pneumoniae ATCC 700603 (MIC=4-8 ¦ÌM), Acinetobacter baumannii ATCC 19606 (MIC=1-2 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC<0.25-0.5 ¦ÌM);##Fungi : Candida albicans ATCC 90028 (MIC=4 ¦ÌM), Cryptococcus neoformans ATCC 208821 (MIC=0.5 ¦ÌM)"	[Ref.28741926] 20.6-32% hemolysis at 64 ¦ÌM against human red blood cells	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bonds between Cys2 and Cys15, Cys6 and Cys11."	L	"[Ref.28741926] CC50 = 26.5 ¡À 2.4 ¦ÌM against CRL-1739, CC50 = 2.0 ¡À 0.1 ¦ÌM against MM96L, CC50 = 14.7 ¡À 1.5 ¦ÌM against HFF-1, CC50 = 20.9 ¡À 1.4 ¦ÌM against HeLa, CC50 = 15.2 ¡À 1.9 ¦ÌM against MCF-7, CC50 = 1.3 ¡À 0.1 ¦ÌM against K-562, CC50 = 15.7 ¡À1.1¦ÌM against HL-60;CC50=10.4 ¡À 1.0¦ÌM against PBMCs."	Not found	28741926	ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459.?	"Sonia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval,Aurelie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan,Yen-Hua Huang, and David J. Craik"	Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties
DRAMP21011	KURRYUYRQRUVTYURGR	18	"[C/U, G1K, L5Y, K8R]cGm (Derived from Gm)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria	"[Ref.28741926]Gram-positive bacteria : Staphylococcuss aureus ATCC 25923 (MIC=8 ¦ÌM);##Gram-negative bacteria : Escherichia coli ATCC 25922 (MIC=1-2 ¦ÌM), Klebsiella pneumoniae ATCC 700603 (MIC=4-16 ¦ÌM), Acinetobacter baumannii ATCC 19606 (MIC=1-2 ¦ÌM), Pseudomonas aeruginosa ATCC 27853 (MIC=1 ¦ÌM);##Fungi : Candida albicans ATCC 90028 (MIC=4 ¦ÌM), Cryptococcus neoformans ATCC 208821 (MIC=0.5-1 ¦ÌM)"	[Ref.28741926] 17.8-24% hemolysis at 64 ¦ÌM against human red blood cells	Cyclic	No specific N-terminal	No specific C-terminal	"Disulfide bonds between SeCys2 and SeCys15, SeCys6 and SeCys11. The 'U' in sequence is SelenoCys."	L	"[Ref.28741926] CC50 = 46.2 ¡À 7.6 ¦ÌM against CRL-1739, CC50 = 2.3 ¡À 0.2 ¦ÌM against MM96L, CC50 = 30.8 ¡À 2.0 ¦ÌM against HFF-1, CC50 = 36.2 ¡À 2.8 ¦ÌM against HeLa, CC50 = 29.0 ¡À 3.7 ¦ÌM against MCF-7, CC50 = 6.4 ¡À 0.6 ¦ÌM against K-562, CC50 = 33.3 ¡À7.4¦ÌM against HL-60;CC50=9.5 ¡À 0.5¦ÌM against PBMCs."	Not found	28741926	ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459.?	"Sonia Troeira Henriques, Nicole Lawrence, Stephanie Chaousis, Anjaneya S. Ravipati, Olivier Cheneval,Aurelie H. Benfield, Alysha G. Elliott, Angela Maria Kavanagh, Matthew A. Cooper, Lai Yue Chan,Yen-Hua Huang, and David J. Craik"	Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties
DRAMP21012	KILRGVCKKIMRTFLRRISKDILTGKK	27	"NK-2 (Mammals, Animals)"	No entry found	Not found	Not found	Mammal	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Not found	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.29043494]Gram-positive bacteria : Staphylococcus aureus (MIC=2 ¦ÌM), Staphylococcus epidermidis (MIC=2 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MIC=4 ¦ÌM), Pseudomonas aeruginosa (MIC=8 ¦ÌM)"	"[Ref.29043494] 2.5% hemolysis at 10 ¦Ìg/ml , 8% hemolysis at 25 ¦Ìg/ml , 22% hemolysis at 50 ¦Ìg/ml , 32.5% hemolysis at 75 ¦Ìg/ml , 36% hemolysis at 150 ¦Ìg/ml , 38% hemolysis at 300 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.29043494] IC50 = 25.1 ¦ÌM against NK-2. ##IC50 = 8.4 ¦ÌM against EJ. ##IC50 = 4.1 ¦ÌM against PC-3. ##IC50 = 10.1 ¦ÌM against T24. ##IC50 = 13.7  ¦ÌM against HL-60. ##The proliferation inhibition activity on K562 is not significant.	Not found	29043494	Probiotics Antimicrob Proteins. 2018 Mar;10(1):118-127. doi: 10.1007/s12602-017-9335-1.	Jiexi Yan & Xiaolei Liang & Chang Liu & Yuemei Cheng & Lanxia Zhou & Kairong Wang & Li Zhao	Influence of Proline Substitution on the Bioactivity of Mammalian-Derived Antimicrobial Peptide NK-2
DRAMP21013	KILRGVCKKIMRPFLRRISKDILTGKK	27	NK-pro (Derived from NK-2)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria	"[Ref.29043494]Gram-positive bacteria : Staphylococcus aureus (MIC=4 ¦ÌM), Staphylococcus epidermidis (MIC=4 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MIC=4 ¦ÌM), Pseudomonas aeruginosa (MIC=16 ¦ÌM)"	"[Ref.29043494] 0.3% hemolysis at 10 ¦Ìg/ml , 2% hemolysis at 25 ¦Ìg/ml , 5.5% hemolysis at 50 ¦Ìg/ml , 8% hemolysis at 75 ¦Ìg/ml , 15% hemolysis at 150 ¦Ìg/ml , 28% hemolysis at 300 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.29043494] IC50 = 43.7 ¦ÌM against NK-2. ##IC50 = 23.3 ¦ÌM against EJ. ##IC50 = 9.3 ¦ÌM against PC-3. ##IC50 = 33.0 ¦ÌM against T24. ##IC50 = 26.1  ¦ÌM against HL-60. ####The proliferation inhibition activity on K562 is not significant.	Not found	29043494	Probiotics Antimicrob Proteins. 2018 Mar;10(1):118-127. doi: 10.1007/s12602-017-9335-1.	Jiexi Yan & Xiaolei Liang & Chang Liu & Yuemei Cheng & Lanxia Zhou & Kairong Wang & Li Zhao	Influence of Proline Substitution on the Bioactivity of Mammalian-Derived Antimicrobial Peptide NK-2
DRAMP21014	KILPGVCKKIMRPFLRRISKDILTGKK	27	NK-dpro (Derived from NK-2)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antitumor"	Synthetic form	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria	"[Ref.29043494]Gram-positive bacteria : Staphylococcus aureus (MIC=8 ¦ÌM), Staphylococcus epidermidis (MIC=8 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MIC=8 ¦ÌM), Pseudomonas aeruginosa (MIC=32 ¦ÌM)"	"[Ref.29043494] 0% hemolysis at 10 ¦Ìg/ml , 2% hemolysis at 25 ¦Ìg/ml , 3% hemolysis at 50 ¦Ìg/ml , 4.5% hemolysis at 75 ¦Ìg/ml , 10% hemolysis at 150 ¦Ìg/ml , 20% hemolysis at 300 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.29043494] IC50 = 32.5 ¦ÌM against NK-2. ##IC50 = 28.7 ¦ÌM against EJ. ##IC50 = 9.6 ¦ÌM against PC-3. ##IC50 = 39.6 ¦ÌM against T24. ##IC50 = 48.4  ¦ÌM against HL-60. ##The proliferation inhibition activity on K562 is not significant.	Not found	29043494	Probiotics Antimicrob Proteins. 2018 Mar;10(1):118-127. doi: 10.1007/s12602-017-9335-1.	Jiexi Yan & Xiaolei Liang & Chang Liu & Yuemei Cheng & Lanxia Zhou & Kairong Wang & Li Zhao	Influence of Proline Substitution on the Bioactivity of Mammalian-Derived Antimicrobial Peptide NK-2
DRAMP21024	FFSLIPSLVGGLISAFK	17	"Stigmurin (Tityus, Scorpionida, Arachnida)"	No entry found	Not found	Not found	Scorpion Tityus stigmurus	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Candida glabrata, Candida krusei"	"[Ref.30709056]Gram-positive bacteria : Staphylococcus aureus (ATCC 29213)(MIC=9.4 ¦ÌM), Staphylococcus epidermidis (ATCC 12228)(MIC=9.4 ¦ÌM), Enterococcus faecalis (ATCC 4028)(MIC>150 ¦ÌM);##Gram-negative bacteria : Pseudomonas aeruginosa (ATCC 27853)(MIC>150 ¦ÌM), Escherichia coli (ATCC 25922)(MIC>150 ¦ÌM), Enterobacter cloacae (ATCC 13047)(MIC>150 ¦ÌM);##Fungi : Candida albicans (ATCC 90028)(MIC=37.5 ¦ÌM), Candida glabrata (ATCC 90030)(MIC>150 ¦ÌM), Candida krusei (ATCC 6258)(MIC>150 ¦ÌM)"	"[Ref.30709056] 7% hemolysis at 1.2 ¦Ìg/ml , 4% hemolysis at 2.3 ¦Ìg/ml , 2% hemolysis at 4.7 ¦Ìg/ml , 0% hemolysis at 9.4 ¦Ìg/ml , 3% hemolysis at 18.8 ¦Ìg/ml , 2% hemolysis at 37.5 ¦Ìg/ml , 3% hemolysis at 75 ¦Ìg/ml , 5% hemolysis at 150 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.30709056] No cytotoxicity information found.	Not found	30709056	Int J Mol Sci. 2019 Jan 31;20(3). pii: E623. doi: 10.3390/ijms20030623.	"Bruno Amorim-Carmo , Alessandra Daniele-Silva , Adriana M. S. Parente ,Allanny A. Furtado , Eneas Carvalho , Johny W. F. Oliveira , Elizabeth C. G. Santos , Marcelo S. Silva , S¨¦rgio R. B. Silva , Arn¨®bio A. Silva-J¨²nior , Norberto K. Monteiro and Matheus F. Fernandes-Pedrosa"	Potent and Broad-Spectrum Antimicrobial Activity of Analogs from the Scorpion Peptide Stigmurin
DRAMP21025	FFSLIPSLVKKLIKAFK	17	StigA25 (Derived from Stigmurin)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Candida glabrata, Candida krusei"	"[Ref.30709056]Gram-positive bacteria : Staphylococcus aureus (ATCC 29213)(MIC=1.2 ¦ÌM), Staphylococcus epidermidis (ATCC 12228)(MIC=2.3 ¦ÌM), Enterococcus faecalis (ATCC 4028)(MIC=4.7 ¦ÌM);##Gram-negative bacteria : Pseudomonas aeruginosa (ATCC 27853)(MIC=4.7 ¦ÌM), Escherichia coli (ATCC 25922)(MIC=2.3 ¦ÌM), Enterobacter cloacae (ATCC 13047)(MIC=18.8 ¦ÌM);##Fungi : Candida albicans (ATCC 90028)(MIC=9.4 ¦ÌM), Candida glabrata (ATCC 90030)(MIC=9.4 ¦ÌM), Candida krusei (ATCC 6258)(MIC=9.4 ¦ÌM)"	"[Ref.30709056] 1% hemolysis at 1.2 ¦Ìg/ml , 5% hemolysis at 2.3 ¦Ìg/ml , 9% hemolysis at 4.7 ¦Ìg/ml , 19% hemolysis at 9.4 ¦Ìg/ml , 33% hemolysis at 18.8 ¦Ìg/ml , 60% hemolysis at 37.5 ¦Ìg/ml , 78% hemolysis at 75 ¦Ìg/ml , 93% hemolysis at 150 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.30709056] No cytotoxicity information found.	Not found	30709056	Int J Mol Sci. 2019 Jan 31;20(3). pii: E623. doi: 10.3390/ijms20030623.	"Bruno Amorim-Carmo , Alessandra Daniele-Silva , Adriana M. S. Parente ,Allanny A. Furtado , Eneas Carvalho , Johny W. F. Oliveira , Elizabeth C. G. Santos , Marcelo S. Silva , S¨¦rgio R. B. Silva , Arn¨®bio A. Silva-J¨²nior , Norberto K. Monteiro and Matheus F. Fernandes-Pedrosa"	Potent and Broad-Spectrum Antimicrobial Activity of Analogs from the Scorpion Peptide Stigmurin
DRAMP21026	FFKLIPKLVKKLIKAFK	17	StigA31 (Derived from Stigmurin)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Candida glabrata, Candida krusei"	"[Ref.30709056]Gram-positive bacteria : Staphylococcus aureus (ATCC 29213)(MIC=2.3 ¦ÌM), Staphylococcus epidermidis (ATCC 12228)(MIC=2.3 ¦ÌM), Enterococcus faecalis (ATCC 4028)(MIC=1.2 ¦ÌM);##Gram-negative bacteria : Pseudomonas aeruginosa (ATCC 27853)(MIC=2.3 ¦ÌM), Escherichia coli (ATCC 25922)(MIC=1.2 ¦ÌM), Enterobacter cloacae (ATCC 13047)(MIC=4.7 ¦ÌM);##Fungi : Candida albicans (ATCC 90028)(MIC=4.7 ¦ÌM), Candida glabrata (ATCC 90030)(MIC=4.7 ¦ÌM), Candida krusei (ATCC 6258)(MIC=4.7 ¦ÌM)"	"[Ref.30709056] 1% hemolysis at 1.2 ¦Ìg/ml , 6% hemolysis at 2.3 ¦Ìg/ml , 10% hemolysis at 4.7 ¦Ìg/ml , 12 % hemolysis at 9.4 ¦Ìg/ml , 23% hemolysis at 18.8 ¦Ìg/ml , 45% hemolysis at 37.5 ¦Ìg/ml , 65% hemolysis at 75 ¦Ìg/ml , 70% hemolysis at 150 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.30709056] No cytotoxicity information found.	Not found	30709056	Int J Mol Sci. 2019 Jan 31;20(3). pii: E623. doi: 10.3390/ijms20030623.	"Bruno Amorim-Carmo , Alessandra Daniele-Silva , Adriana M. S. Parente ,Allanny A. Furtado , Eneas Carvalho , Johny W. F. Oliveira , Elizabeth C. G. Santos , Marcelo S. Silva , S¨¦rgio R. B. Silva , Arn¨®bio A. Silva-J¨²nior , Norberto K. Monteiro and Matheus F. Fernandes-Pedrosa"	Potent and Broad-Spectrum Antimicrobial Activity of Analogs from the Scorpion Peptide Stigmurin
DRAMP21027	ALWKKILKNAGKAALNKINQIVQ	23	"K5, 17-DPS3 (Derived from dermaseptin-PS3 (DPS3))"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix"	"These three peptides existed in random coils in aqueous solution, they all adopted "	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans"	[Ref.30087268]Gram-positive bacteria : Staphylococcuss aureus (NCTC 10788)(MIC=8 ¦ÌM);##Gram-negative bacteria : Escherichia coli (NCTC 10418)(MIC=8 ¦ÌM);##Fungi : Candida albicans (NCYC 1467)(MIC=4 ¦ÌM)	"[Ref.30087268] 8% hemolysis at 0 ¦ÌM , 40% hemolysis at 1 ¦ÌM , 90% hemolysis at 2 ¦ÌM against horse red blood cells"	Linear	Free	Amidation	None	L	[Ref.30087268] IC50 = 18.20 ¦ÌM for H157. ##IC50 = 18.20 ¦ÌM for PC3. ##IC50 = 132.10 ¦ÌM for HMEC-1	Not found	30087268	Toxins (Basel). 2018 Aug 7;10(8). pii: E320. doi: 10.3390/toxins10080320.	"Yining Tan ,Xiaoling Chen , Chengbang Ma , Xinping Xi ,Lei Wang , Mei Zhou ,James F. Burrows ,Hang Fai Kwok 2 ID and Tianbao Chen"	"Biological Activities of Cationicity-Enhanced and Hydrophobicity-Optimized Analogues of an Antimicrobial Peptide, Dermaseptin-PS3, from the Skin Secretion of Phyllomedusa sauvagii"
DRAMP21028	ALWKDILKNLLKAALNEINQIVQ	23	"L10, 11-DPS3 (Derived from dermaseptin-PS3 (DPS3))"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix"	"These three peptides existed in random coils in aqueous solution, they all adopted "	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans"	[Ref.30087268]Gram-positive bacteria : Staphylococcuss aureus (NCTC 10788)(MIC=8 ¦ÌM);##Gram-negative bacteria : Escherichia coli (NCTC 10418)(MIC=16 ¦ÌM);##Fungi : Candida albicans (NCYC 1467)(MIC=16 ¦ÌM)	"[Ref.30087268] 20% hemolysis at 0 ¦ÌM , 70% hemolysis at 1 ¦ÌM , 95% hemolysis at 2 ¦ÌM against horse red blood cells"	Linear	Free	Amidation	None	L	[Ref.30087268] IC50 = 0.12 ¦ÌM for H157. ##IC50 = 1.85 ¦ÌM for PC3. ##IC50 = 8.76 ¦ÌM for HMEC-1	Not found	30087268	Toxins (Basel). 2018 Aug 7;10(8). pii: E320. doi: 10.3390/toxins10080320.	"Yining Tan ,Xiaoling Chen , Chengbang Ma , Xinping Xi ,Lei Wang , Mei Zhou ,James F. Burrows ,Hang Fai Kwok 2 ID and Tianbao Chen"	"Yining Tan ,Xiaoling Chen , Chengbang Ma , Xinping Xi ,Lei Wang , Mei Zhou ,James F. Burrows ,Hang Fai Kwok 2 ID and Tianbao Chen"
DRAMP21029	ATYRTGRATRESLSGVEISGRLYRLR	26	D5R (Derived from HD5) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Alpha helix, beta sheet, beta turn"	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Saccharomyces cerevisiae"	"[Ref.26206286]Gram-positive bacteria : Staphylococcus aureus (NCTC 8530)(MIC=100 ¦ÌM), Bacillus subtilis (NCIM 2162)(MIC=20 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MG 1655)(MIC=50 ¦ÌM), Pseudomonas aeruginosa (NCTC 6750)(MIC=100 ¦ÌM);##Fungi : Candida albicans (ATCC 18804)(MIC=20 ¦ÌM), Saccharomyces cerevisiae (BY4741)(MIC=100 ¦ÌM)"	[Ref.26206286] 0% hemolysis at 100¦ÌM against human red blood cells	Linear	Free	Free	None	L	[Ref.26206286] No cytotoxic information found.	Not found	26206286	Peptides. 2015 Sep;71:128-40. doi: 10.1016/j.peptides.2015.07.009. Epub 2015 Jul 20.	Basil Mathew Ramakrishnan Nagaraj	Antimicrobial activity of human-defensin 5 and its linear analogs: N-terminal fatty acylation results in enhanced antimicrobial activity of the linear analogs
DRAMP21030	ATYrTGrATrESLSGVEISGrLYrLR	26	D5r (Derived from HD5) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Alpha helix, beta sheet, beta turn"	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans"	"[Ref.26206286]Gram-positive bacteria : Staphylococcus aureus (NCTC 8530)(MIC=100 ¦ÌM), Bacillus subtilis (NCIM 2162)(MIC=50 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MG 1655)(MIC=50 ¦ÌM), Pseudomonas aeruginosa (NCTC 6750)(MIC=200 ¦ÌM);##Fungi : Candida albicans (ATCC 18804)(MIC=20 ¦ÌM)"	[Ref.26206286] 0% hemolysis at 100¦ÌM against human red blood cells	Linear	Free	Free	None	"Mixed(D-Arg4, D-Arg7, D-Arg10, D-Arg21, D-Arg24)"	[Ref.26206286] No cytotoxic information found.	Not found	26206286	Peptides. 2015 Sep;71:128-40. doi: 10.1016/j.peptides.2015.07.009. Epub 2015 Jul 20.	Basil Mathew Ramakrishnan Nagaraj	Antimicrobial activity of human-defensin 5 and its linear analogs: N-terminal fatty acylation results in enhanced antimicrobial activity of the linear analogs
DRAMP21031	ATYRTGRATRESLSGVEISGRLYRLR	26	MyD5R (Derived from HD5) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Alpha helix, beta sheet, beta turn"	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Saccharomyces cerevisiae"	"[Ref.26206286]Gram-positive bacteria : Staphylococcus aureus (NCTC 8530)(MIC=7.5 ¦ÌM), Bacillus subtilis (NCIM 2162)(MIC=20 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MG 1655)(MIC=5 ¦ÌM), Pseudomonas aeruginosa (NCTC 6750)(MIC=10 ¦ÌM);##Fungi : Candida albicans (ATCC 18804)(MIC=10 ¦ÌM), Saccharomyces cerevisiae (BY4741)(MIC=20 ¦ÌM)"	"[Ref.26206286] 23% hemolysis at 10 ¦ÌM , 50% hemolysis at 20 ¦ÌM , 75% hemolysis at 50 ¦ÌM , 87.5% hemolysis at 100 ¦ÌM against human red blood cells"	Linear	Acylation (Conjugated with myristic acid)	Free	None	L	[Ref.26206286] No cytotoxic information found.	Not found	26206286	Peptides. 2015 Sep;71:128-40. doi: 10.1016/j.peptides.2015.07.009. Epub 2015 Jul 20.	Basil Mathew Ramakrishnan Nagaraj	Antimicrobial activity of human-defensin 5 and its linear analogs: N-terminal fatty acylation results in enhanced antimicrobial activity of the linear analogs
DRAMP21032	ATYrTGrATrESLSGVEISGrLYrLR	26	MyD5r (Derived from HD5) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Alpha helix, beta sheet, beta turn"	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Saccharomyces cerevisiae"	"[Ref.26206286]Gram-positive bacteria : Staphylococcus aureus (NCTC 8530)(MIC=7.5 ¦ÌM), Bacillus subtilis (NCIM 2162)(MIC=5 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MG 1655)(MIC=5 ¦ÌM), Pseudomonas aeruginosa (NCTC 6750)(MIC=7.5 ¦ÌM);##Fungi : Candida albicans (ATCC 18804)(MIC=10 ¦ÌM), Saccharomyces cerevisiae (BY4741)(MIC=20 ¦ÌM)"	"[Ref.26206286] 17% hemolysis at 10 ¦ÌM , 25% hemolysis at 20 ¦ÌM , 50% hemolysis at 50 ¦ÌM , 70% hemolysis at 100 ¦ÌM against human red blood cells"	Linear	Acylation (Conjugated with myristic acid)	Free	None	"Mixed(D-Arg4, D-Arg7, D-Arg10, D-Arg21, D-Arg24)"	[Ref.26206286] No cytotoxic information found.	Not found	26206286	Peptides. 2015 Sep;71:128-40. doi: 10.1016/j.peptides.2015.07.009. Epub 2015 Jul 20.	Basil Mathew Ramakrishnan Nagaraj	Antimicrobial activity of human-defensin 5 and its linear analogs: N-terminal fatty acylation results in enhanced antimicrobial activity of the linear analogs
DRAMP21033	ATYRTGRATRESLSGVEISGRLYRLR	26	LaD5R (Derived from HD5) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Alpha helix, beta sheet, beta turn"	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Saccharomyces cerevisiae"	"[Ref.26206286]Gram-positive bacteria : Staphylococcus aureus (NCTC 8530)(MIC=2 ¦ÌM), Bacillus subtilis (NCIM 2162)(MIC=5 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MG 1655)(MIC=20 ¦ÌM), Pseudomonas aeruginosa (NCTC 6750)(MIC=10 ¦ÌM);##Fungi : Candida albicans (ATCC 18804)(MIC=10 ¦ÌM), Saccharomyces cerevisiae (BY4741)(MIC=10 ¦ÌM)"	[Ref.26206286] 0% hemolysis at 100¦ÌM against human red blood cells	Linear	Acylation (Conjugated with lauric acid)	Free	None	L	[Ref.26206286] No cytotoxic information found.	Not found	26206286	Peptides. 2015 Sep;71:128-40. doi: 10.1016/j.peptides.2015.07.009. Epub 2015 Jul 20.	Basil Mathew Ramakrishnan Nagaraj	Antimicrobial activity of human-defensin 5 and its linear analogs: N-terminal fatty acylation results in enhanced antimicrobial activity of the linear analogs
DRAMP21034	ATYrTGrATrESLSGVEISGrLYrLR	26	LaD5r (Derived from HD5) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Alpha helix, beta sheet, beta turn"	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Saccharomyces cerevisiae"	"[Ref.26206286]Gram-positive bacteria : Staphylococcus aureus (NCTC 8530)(MIC=20 ¦ÌM), Bacillus subtilis (NCIM 2162)(MIC=5 ¦ÌM);##Gram-negative bacteria : Escherichia coli (MG 1655)(MIC=10 ¦ÌM), Pseudomonas aeruginosa (NCTC 6750)(MIC=50 ¦ÌM);##Fungi : Candida albicans (ATCC 18804)(MIC=10 ¦ÌM), Saccharomyces cerevisiae (BY4741)(MIC=10 ¦ÌM)"	[Ref.26206286] 0% hemolysis at 100¦ÌM against human red blood cells	Linear	Acylation (Conjugated with lauric acid)	Free	None	"Mixed(D-Arg4, D-Arg7, D-Arg10, D-Arg21, D-Arg24)"	[Ref.26206286] No cytotoxic information found.	Not found	26206286	Peptides. 2015 Sep;71:128-40. doi: 10.1016/j.peptides.2015.07.009. Epub 2015 Jul 20.	Basil Mathew Ramakrishnan Nagaraj	Antimicrobial activity of human-defensin 5 and its linear analogs: N-terminal fatty acylation results in enhanced antimicrobial activity of the linear analogs
DRAMP21050	AWCFRVCYRGICYRRCR	17	TP1[K1A] (Derived from TP1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.03 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=0.5 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.03 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.06 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=2 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.125 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.125 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=0.5 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.25 ¦Ìg/ml)"	[Ref.28960954] MHC10=2.1 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-1
DRAMP21051	KACFRVCYRGICYRRCR	17	TP1[W2A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.5 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=8 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.5 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=4 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.5 ¦Ìg/ml)"	[Ref.28960954] MHC10=8 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-2
DRAMP21052	KWAFRVCYRGICYRRSR	17	"TP1[C3A, C16S] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.5 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC>16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=4 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=16 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=16 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC>16 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC>16 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC>16 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC>16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=4 ¦Ìg/ml)"	[Ref.28960954] MHC10=8 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	Disulfide bond between Cys7 and Cys12.	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-3
DRAMP21053	KWCARVCYRGICYRRCR	17	TP1[F4A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.25 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=4 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.5 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=2 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.5 ¦Ìg/ml)"	[Ref.28960954] MHC10=40 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-4
DRAMP21054	KWCFAVCYRGICYRRCR	17	TP1[R5A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.03 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=0.5 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=8 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.06 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.125 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=0.5 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=4 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.25 ¦Ìg/ml)"	[Ref.28960954] MHC10=2 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-5
DRAMP21055	KWCFRACYRGICYRRCR	17	TP1[V6A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.25 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=4 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=1 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=2 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=1 ¦Ìg/ml)"	[Ref.28960954] MHC10=1.2 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-6
DRAMP21056	KWCFRVAYRGISYRRCR	17	"TP1[C7A, C12S] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.25 [Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.25 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=2 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=4 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=2 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=4 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.5 ¦Ìg/ml)"	[Ref.28960954] MHC10=1 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	Disulfide bond between Cys3 and Cys16.	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis.2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-7
DRAMP21057	KWCFRVCARGICYRRCR	17	TP1[Y8A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.25 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=4 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.06 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=8 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=0.125 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.5 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=1 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=2 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC= ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.5 ¦Ìg/ml)"	[Ref.28960954] MHC10=8 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	"Disulfide bond between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-8
DRAMP21058	KWCFRVCYAGICYRRCR	17	TP1[R9A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.125 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=1 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.03 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=2 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.06 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.125 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=1 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=2 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.25 ¦Ìg/ml)"	[Ref.28960954] MHC10=2 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-9
DRAMP21059	KWCFRVCYRAICYRRCR	17	TP1[G10A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.03 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=0.5 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.06 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.03 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=4 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.6 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.6 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=0.5 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=2 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.06 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.5 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-10
DRAMP21060	KWCFRVCYRGACYRRCR	17	TP1[I11A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.125 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=2 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=8 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=1 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=2 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.5 ¦Ìg/ml)"	[Ref.28960954] MHC10=32 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation (Arg17)	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-11
DRAMP21061	KWCFRVSYRGIAYRRCR	17	"TP1[C7S, C12A] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.125 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=4 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=16 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=8 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.5 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=1 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=8 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=2 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.5 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.6 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	Disulfide bond between Cys3 and Cys16.	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-12
DRAMP21062	KWCFRVCYRGICARRCR	17	TP1[Y13A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.06 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=4 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=8 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.125 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=2 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=4 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.5 ¦Ìg/ml)"	[Ref.28960954] MHC10=1 [Ref.28960954] MHC10=1 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bond between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-13
DRAMP21063	KWCFRVCYRGICYARCR	17	TP1[R14A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.125 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=0.5 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.06 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=1 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.125 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.125 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.125 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=0.25 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.25 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.5 [Ref.28960954] MHC10=0.5 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-14
DRAMP21064	KWCFRVCYRGICYRACR	17	TP1[R15A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.03 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=4 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=4 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=4 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=2 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.25 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.45 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-15
DRAMP21065	KWSFRVCYRGICYRRAR	17	"TP1[C3S, C16A] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.125 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=4 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=1 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=4 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=4 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.25 ¦Ìg/ml)"	[Ref.28960954] MHC10=3 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	Disulfide bond between Cys7 and Cys12.	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-16
DRAMP21066	KWCFRVCYRGICYRRCA	17	TP1[R17A] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.015 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=0.5 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.015 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=4 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.125 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.125 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=0.5 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=4 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.25 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.45 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-17
DRAMP21067	KWAFRVCYRGICYRRAR	17	"TP1[C3A, C16A] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.125 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=8 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=2 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=8 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=1 ¦Ìg/ml)"	[Ref.28960954] MHC10=40 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	Disulfide bond between Cys7 and Cys12.	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-18
DRAMP21068	KWCFRVAYRGIAYRRCR	17	"TP1[C7A, C12A] (Derived from TP1)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.125 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=2 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=1 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=2 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=1 ¦Ìg/ml)"	[Ref.28960954] MHC10=8 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	Disulfide bond between Cys3 and Cys16.	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-19
DRAMP21069	KWAFRVAYRGIAYRRAR	17	"TP1[C3A, C7A, C12A, C16A] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=1 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=8 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=16 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=16 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=16 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=4 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=4 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC>16 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC>16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=1 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.24 ¦Ìg/ml against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-20
DRAMP21070	KWCFRRCYAGICYRRCR	17	"TP1[V6R, R9A] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.25 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC>16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC>16 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=16 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC>16 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=16 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC>16 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC>16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=4 ¦Ìg/ml)"	[Ref.28960954] MHC10=11 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-21
DRAMP21071	RWCFRVCYRGICYRRCR	17	TP1[K1R] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.125 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=1 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=4 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.125 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=0.5 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=4 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.25 ¦Ìg/ml)"	[Ref.28960954] MHC10=1 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-22
DRAMP21072	KWCGRVCYRGICYRRCR	17	TP1[F4G] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.5 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.5 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=2 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=1 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=2 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.47 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-23
DRAMP21073	KWCSRVCYRGICYRRCR	17	TP1[F4S] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.5 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=4 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=4 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.5 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=2 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=4 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC>16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=4 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.23 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-24
DRAMP21074	KWCFRVCGRGICYRRCR	17	TP1[Y8G] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.5 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=8 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=8 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.5 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=2 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=4 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC>16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=4 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.4 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-25
DRAMP21075	KWCFRVCYRGGCYRRCR	17	TP1[I11G] (Derived from TP1) 	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.25 [Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.25 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=4 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=8 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.5 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=1 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=4 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=1 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.2 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12."	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-26
DRAMP21076	KWCARVCARGACYRRCR	17	"TP1[F4A, Y8A, I11A] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC>16 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC>16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=8 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC>16 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC>16 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC>16 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC>16 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC>16 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC>16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC>16 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.9 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis.2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-27
DRAMP21077	KWCFVCYRGICYRRCG	16	"TP1[-R5, R17G] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=1 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC>16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=8 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC>16 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC>16 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC>16 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=16 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC>16 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC>16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=4 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.3 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis.2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-28
DRAMP21078	AWCARVCYRGICYRRCR	17	"TP1[K1A, F4A] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=16 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC>16 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=2 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=4 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=4 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=4 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC>16 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=2 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=16 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=8 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC>16 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC>16 ¦Ìg/ml)"	[Ref.28960954] MHC10=32 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-29
DRAMP21079	AWCFRVCARGICYRRCR	17	"TP1[K1A, Y8A] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.5 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=8 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=1 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=8 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=1 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=4 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=2 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.4 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-30
DRAMP21080	AWCFRVCYRGACYRRCR	17	"TP1[K1A, I11A] (Derived from TP1) "	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.125 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=4 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.125 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.25 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=4 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.25 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=2 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC>16 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=1 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.2 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-31
DRAMP21081	KWCFRVCYAGICYRRCA	17	"TP1[R9A, R17A] (Derived from TP1)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Cryptococcus neoformans"	"[Ref.28960954] Gram-positive bacteria : Bacillus subtilis ATCC 6051(MIC=0.06 ¦Ìg/ml), Staphylococcus aureus ATCC 43300 (MRSA)(MIC=2 ¦Ìg/ml);##Gram-negative bacteria : Escherichia coli ATCC 25922(MIC=0.03 ¦Ìg/ml), Klebsiella pneumoniae ATCC 13883(MIC=0.06 ¦Ìg/ml), Klebsiella pneumoniae ATCC 700603 (MDR)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae BAA 2146 (NDM-1 pos)(MIC=0.5 ¦Ìg/ml), Klebsiella pneumoniae clinical isolate 100650661 : 1 (XDR;PmxR)(MIC=4 ¦Ìg/ml), Acinetobacter baumannii ATCC 19606(MIC=0.25 ¦Ìg/ml), Acinetobacter baumannii clinical isolate 100734512 : 2 (XDR;PmxR)(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa ATCC 27853(MIC=0.5 ¦Ìg/ml), Pseudomonas aeruginosa FADDIFA070 (PmxR)(MIC=2 ¦Ìg/ml);##Fungi : Candida albicans ATCC 90028(MIC=8 ¦Ìg/ml), Cryptococcus neoformans ATCC 208821(MIC=0.5 ¦Ìg/ml)"	[Ref.28960954] MHC10=0.2 ¦Ìg/ml against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys7 and Cys12"	L	"[Ref.28960954] The peptide did not show cytotoxicity against HEK293 cells at the highest tested concentration, 100 ¦Ìg/ml."	Not found	28960954	ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123.	"Ingrid A. Edwards , Alysha G. Elliott , Angela M. Kavanagh , Mark A. T. Blaskovich , and Matthew A. Cooper"	Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-32
DRAMP21082	KWCFCVCYRGICRCRCRG	18	ccTP 3 (Derived from TP2)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Beta tile	Although there is insufficient information to deconvolute these CD spectra of these two-b-strand cyclic cystine-knot structures due to the various contributions by 	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Candida kefyr, Candida tropicalis"	"[Ref.10673369] Gram-positive bacteria : Staphylococcus aureus(MIC=1.3 ¦ÌM(low-salt);MIC=0.9 ¦ÌM(high-salt)), Micrococcus luteus(MIC=0.5 ¦ÌM(low-salt);MIC=0.5 ¦ÌM(high-salt)), Enterococcus faecalis(MIC=1.9 ¦ÌM(low-salt);MIC=1.3 ¦ÌM(high-salt));##Gram-negative bacteria : Escherichia coli(MIC=10.4 ¦ÌM(low-salt);MIC=0.9 ¦ÌM(high-salt)), Pseudomonas aeruginosa(MIC=6.2 ¦ÌM(low-salt);MIC=10.4 ¦ÌM(high-salt)), Primula vulgaris(MIC=16.4 ¦ÌM(low-salt);MIC=28.9 ¦ÌM(high-salt)), Klebsiella oxytoca(MIC=4.0 ¦ÌM(low-salt);MIC=7.6 ¦ÌM(high-salt));##Fungi : Candida albicans(MIC=24.2 ¦ÌM(low-salt);MIC=30.2 ¦ÌM(high-salt)), Candida kefyr(MIC=1.1 ¦ÌM(low-salt);MIC=4.3 ¦ÌM(high-salt)), Candida tropicalis(MIC=12.4 ¦ÌM(low-salt);MIC=3.9 ¦ÌM(high-salt))"	[Ref.10673369] EC25=590 ¦ÌM against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys5 and Cys14, Cys7 and Cys12."	L	[Ref.10673369] No cytotoxicity information found.	Not found	10673369	Biochem Biophys Res Commun. 2000 Jan 27;267(3):783-90.	"James P. Tam, Yi-An Lu, and Jin-Long Yang"	Marked Increase in Membranolytic Selectivity of Novel Cyclic Tachyplesins Constrained with an Antiparallel Two-b Strand Cystine Knot Framework
DRAMP21083	KWCRCVCRRGICRCFCRG	18	ccTP 5 (Derived from TP2)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Beta tile	Although there is insufficient information to deconvolute these CD spectra of these two-b-strand cyclic cystine-knot structures due to the various contributions by 	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Candida kefyr, Candida tropicalis"	"[Ref.10673369] Gram-positive bacteria : Staphylococcus aureus(MIC=1.7 ¦ÌM(low-salt);MIC=1.3 ¦ÌM(high-salt)), Micrococcus luteus(MIC=0.5 ¦ÌM(low-salt);MIC=0.8 ¦ÌM(high-salt)), Enterococcus faecalis(MIC=0.7 ¦ÌM(low-salt);MIC=0.5 ¦ÌM(high-salt));##Gram-negative bacteria : Escherichia coli(MIC=5.5 ¦ÌM(low-salt);MIC=1.2 ¦ÌM(high-salt)), Pseudomonas aeruginosa(MIC=3.9 ¦ÌM(low-salt);MIC=4.7 ¦ÌM(high-salt)), Primula vulgaris(MIC=16.8 ¦ÌM(low-salt);MIC=55.6 ¦ÌM(high-salt)), Klebsiella oxytoca(MIC=2.4 ¦ÌM(low-salt);MIC=5.4 ¦ÌM(high-salt));##Fungi : Candida albicans(MIC=7.1 ¦ÌM(low-salt);MIC=5.1 ¦ÌM(high-salt)), Candida kefyr(MIC=4.2 ¦ÌM(low-salt);MIC=0.7 ¦ÌM(high-salt)), Candida tropicalis(MIC=1.9 ¦ÌM(low-salt);MIC=4.8 ¦ÌM(high-salt))"	[Ref.10673369] EC25=920 ¦ÌM against human red blood cells	Cyclic	Free	Amidation	"Disulfide bonds between Cys3 and Cys16, Cys5 and Cys14, Cys7 and Cys12."	L	[Ref.10673369] No cytotoxicity information found.	Not found	10673369	Biochem Biophys Res Commun. 2000 Jan 27;267(3):783-90.	"James P. Tam, Yi-An Lu, and Jin-Long Yang"	Marked Increase in Membranolytic Selectivity of Novel Cyclic Tachyplesins Constrained with an Antiparallel Two-b Strand Cystine Knot Framework
DRAMP21084	GWCRCVCRRGICRCFCRK	18	ccTP 6 (Derived from TP2)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Beta tile	Although there is insufficient information to deconvolute these CD spectra of these two-b-strand cyclic cystine-knot structures due to the various contributions by 	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, Antifungal activity agaist Candida albicans, Candida kefyr, Candida tropicalis"	"[Ref.10673369] Gram-positive bacteria : Staphylococcus aureus(MIC=1.7 ¦ÌM(low-salt);MIC=0.7 ¦ÌM(high-salt)), Micrococcus luteus(MIC=0.3 ¦ÌM(low-salt);MIC=0.4 ¦ÌM(high-salt)), Enterococcus faecalis(MIC=1.4 ¦ÌM(low-salt);MIC=1.2 ¦ÌM(high-salt));##Gram-negative bacteria : Escherichia coli(MIC=6.1 ¦ÌM(low-salt);MIC=1.2 ¦ÌM(high-salt)), Pseudomonas aeruginosa(MIC=2.0 ¦ÌM(low-salt);MIC=4.7 ¦ÌM(high-salt)), Primula vulgaris(MIC=17.0 ¦ÌM(low-salt);MIC=39.8 ¦ÌM(high-salt)), Klebsiella oxytoca(MIC=4.1 ¦ÌM(low-salt);MIC=4.1 ¦ÌM(high-salt));##Fungi : Candida albicans(MIC=10.5 ¦ÌM(low-salt);MIC=5.2 ¦ÌM(high-salt)), Candida kefyr(MIC=1.1 ¦ÌM(low-salt);MIC=0.7 ¦ÌM(high-salt)), Candida tropicalis(MIC=2.3 ¦ÌM(low-salt);MIC=1.9 ¦ÌM(high-salt))"	[Ref.10673369] EC25=3900 ¦ÌM against human red blood cells	Cyclic	Free	Amidation (Gly18)	"Disulfide bonds between Cys3 and Cys16, Cys5 and Cys14, Cys7 and Cys12."	L	No cytotoxicity information found	Not found	10673369	Biochem Biophys Res Commun. 2000 Jan 27;267(3):783-90.	"James P. Tam, Yi-An Lu, and Jin-Long Yang"	Marked Increase in Membranolytic Selectivity of Novel Cyclic Tachyplesins Constrained with an Antiparallel Two-b Strand Cystine Knot Framework
DRAMP21165	GIMSSLMKKLKKIIKK	16	HYL-11 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=54 ¦ÌM), Staphylococcus epidermidis(MIC=1.7 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=22 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=7.1 ¦ÌM);##Fungi : Candida albicans(MIC=6.3 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21166	GILSSLLKKLKKIIAK	16	HYL-12 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=16 ¦ÌM), Staphylococcus epidermidis(MIC=1.8 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=8 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=5 ¦ÌM);##Fungi : Candida albicans(MIC=10 ¦ÌM)"	[Ref.26998557] LC50=284 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21164	GIMSSLMKKLAKIIKK	16	HYL-10 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=33 ¦ÌM), Staphylococcus epidermidis(MIC=2.9 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=15 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=5.2 ¦ÌM);##Fungi : Candida albicans(MIC=7.6 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21158	GIMSSLMKKLKKHIAK	16	HYL-4 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC>100 ¦ÌM), Staphylococcus epidermidis(MIC=10 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=26 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=6.4 ¦ÌM);##Fungi : Candida albicans(MIC=12 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21159	GIMISLMKKLAAHIAK	16	HYL-5 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=43 ¦ÌM), Staphylococcus epidermidis(MIC=8.8 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=12 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=47 ¦ÌM);##Fungi : Candida albicans(MIC=12 ¦ÌM)"	[Ref.26998557] LC50=320 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21160	GIMSSLMKKLAAIIAK	16	HYL-6 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=7.2 ¦ÌM), Staphylococcus epidermidis(MIC=5 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=3.6 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=8 ¦ÌM);##Fungi : Candida albicans(MIC=8.4 ¦ÌM)"	[Ref.26998557] LC50=93 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21161	GIMSSLMKKLAKIIAK	16	HYL-7 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=9 ¦ÌM), Staphylococcus epidermidis(MIC=5 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=3.7 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=4.5 ¦ÌM);##Fungi : Candida albicans(MIC=11 ¦ÌM)"	[Ref.26998557] LC50=88 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21162	GIMSSLMKKLKKIIAK	16	HYL-8 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=32 ¦ÌM), Staphylococcus epidermidis(MIC=1.9 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=9 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=5 ¦ÌM);##Fungi : Candida albicans(MIC=5.2 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21163	gimsslmkklkkiiak	16	HYL-9 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=13 ¦ÌM), Staphylococcus epidermidis(MIC=2.2 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=6.3 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=3.2 ¦ÌM);##Fungi : Candida albicans(MIC=8 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	D	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21157	GIMSSLMKKLAAHIKK	16	HYL-3 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=85 ¦ÌM), Staphylococcus epidermidis(MIC=11 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=20 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=23 ¦ÌM);##Fungi : Candida albicans(MIC=5 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21156	GIMSSLMKKLAKHIAK	16	HYL-2 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=63 ¦ÌM), Staphylococcus epidermidis(MIC=6.2 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=15 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=7.9 ¦ÌM);##Fungi : Candida albicans(MIC=14 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21155	GIMSSLMKKLKAHIAK	16	HYL-1 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC>100 ¦ÌM), Staphylococcus epidermidis(MIC=16 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=30 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=26 ¦ÌM);##Fungi : Candida albicans(MIC=23 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21154	GIMSSLMKKLAAHIAK	16	"HYL (Bee, Insecta, Animals)"	No entry found	Not found	Not found	Solitary wild bee Hylaeus signatus	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=63 ¦ÌM), Staphylococcus epidermidis(MIC=13 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=15 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=20 ¦ÌM);##Fungi : Candida albicans(MIC=18 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21139	RLLRPLLQLLKQKLR	15	GNU7 (De novo synthesis)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisiae"	"[Ref.23946320] Gram-positive bacteria : Bacillus subtilis(MIC=2 mg/L), Enterococcus faecalis(MIC=2 mg/L), Micrococcus luteus(MIC=2 mg/L), Staphylococcus aureus(MIC=2 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=2 mg/L), Pseudomonas aeruginosa(MIC=2 mg/L), Salmonella typhimurium(MIC=2 mg/L);##Fungi : Candida albicans(MIC=2 mg/L), Cryptococcus neoformans(MIC=2 mg/L), Saccharomyces cerevisiae(MIC=4 mg/L)"	[Ref.23946320] 0% hemolysis at 140 mg/L against human red blood cells	Linear	Free	Free	None	L	"[Ref.23946320] The cell viability of hPBMCs is at peptide concentrations of 4, 8, 16, 32, 64 ¦Ìg/ml"	Not found	23946320	J Antimicrob Chemother. 2014 Jan;69(1):121-32. doi: 10.1093/jac/dkt322.	"Hyun Kim, Ju Hye Jang, Sun Chang Kim and Ju Hyun Cho"	De novo generation of short antimicrobial peptides with enhanced stability and cell specificity
DRAMP21138	RIIRPIIQIIKQKIR	15	GNU6 (De novo synthesis)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisiae"	"[Ref.23946320] Gram-positive bacteria : Bacillus subtilis(MIC=2 mg/L), Enterococcus faecalis(MIC=2 mg/L), Micrococcus luteus(MIC=2 mg/L), Staphylococcus aureus(MIC=2 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=4 mg/L), Pseudomonas aeruginosa(MIC=2 mg/L), Salmonella typhimurium(MIC=4 mg/L);##Fungi : Candida albicans(MIC=2 mg/L), Cryptococcus neoformans(MIC=2 mg/L), Saccharomyces cerevisiae(MIC=4 mg/L)"	[Ref.23946320] 0% hemolysis at 140 mg/L against human red blood cells	Linear	Free	Free	None	L	"[Ref.23946320] The cell viability of hPBMCs is 102.6%, 102.6%, 107.9%, 96.8% and 97.9% at peptide concentrations of 4, 8, 16, 32, 64 ¦Ìg/ml"	Not found	23946320	J Antimicrob Chemother. 2014 Jan;69(1):121-32. doi: 10.1093/jac/dkt322.	"Hyun Kim, Ju Hye Jang, Sun Chang Kim and Ju Hyun Cho"	De novo generation of short antimicrobial peptides with enhanced stability and cell specificity
DRAMP21137	RVVRPVVQVVKQKVR	15	GNU5 (De novo synthesis)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisiae"	"[Ref.23946320] Gram-positive bacteria : Bacillus subtilis(MIC=16 mg/L), Enterococcus faecalis(MIC=8 mg/L), Micrococcus luteus(MIC=2 mg/L), Staphylococcus aureus(MIC=4 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=32 mg/L), Pseudomonas aeruginosa(MIC=8 mg/L), Salmonella typhimurium(MIC>64 mg/L);##Fungi : Candida albicans(MIC=2 mg/L), Cryptococcus neoformans(MIC=2 mg/L), Saccharomyces cerevisiae(MIC=2 mg/L)"	[Ref.23946320] 0% hemolysis at 140 mg/L against human red blood cells	Linear	Free	Free	None	L	"[Ref.23946320] The cell viability of hPBMCs is at peptide concentrations of 4, 8, 16, 32, 64 ¦Ìg/ml"	Not found	23946320	J Antimicrob Chemother. 2014 Jan;69(1):121-32. doi: 10.1093/jac/dkt322.	"Hyun Kim, Ju Hye Jang, Sun Chang Kim and Ju Hyun Cho"	De novo generation of short antimicrobial peptides with enhanced stability and cell specificity
DRAMP21111	LRRAARWARRLLRR	14	ASA (Derived from SLZP)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Sporothrix schenckii, Trichophyton mentagrophytes, Aspergillus fumigatus, Candida parapsilosis"	"[Ref.25069749] Gram-positive bacteria : Staphylococcus aureus (ATCC 25923)(MIC=3.15 ¦Ìg/ml), Bacillus cereus(MIC=3.15 ¦Ìg/ml);##Gram-negative bacteria : E. coli (ATCC 9637)(MIC=25 ¦Ìg/ml), Pseudomonas aeruginosa (ATCC BAA-427)(MIC=25 ¦Ìg/ml), Klebsiella pneumoniae (ATCC 27736)(MIC=6.25 ¦Ìg/ml);##Fungi : Sporothrix schenckii(MIC=12.5 ¦Ìg/ml), Trichophyton mentagrophytes(MIC=100 ¦Ìg/ml), Aspergillus fumigatus(MIC=50 ¦Ìg/ml), Candida parapsilosis (ATCC 22019)(MIC=12.5 ¦Ìg/ml)"	"[Ref.25069749] 3% hemolysis at 10 ¦Ìg/ml , 5% hemolysis at 20 ¦Ìg/ml , 7.5% hemolysis at 30 ¦Ìg/ml , 10% hemolysis at 40 ¦Ìg/ml , 12% hemolysis at 50 ¦Ìg/ml , 13% hemolysis at 60 ¦Ìg/ml , 15% hemolysis at 70 ¦Ìg/ml , 19% hemolysis at 80 ¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.25069749] The cell viability of murine fibroblast cells (3T3) is 100%, 93.6%, 86.8%, 82.9%, 80% and 77.9% at peptide concentrations of 1.5, 3, 4.5, 6 and 9 ¦ÌM."	Not found	25069749	Amino Acids.?2014 Nov;46(11):2531-43. doi: 10.1007/s00726-014-1802-3.	"Ahmad A, Azmi S, Srivastava S, Kumar A, Tripathi JK, Mishra NN, Shukla PK, Ghosh JK"	Design and characterization of short antimicrobial peptides using leucine zipper templates with selectivity towards microorganisms
DRAMP21112	LRRllRWlRRLLRR	14	DLSA (Derived from SLZP)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Sporothrix schenckii, Trichophyton mentagrophytes, Aspergillus fumigatus, Candida parapsilosis"	"[Ref.25069749] Gram-positive bacteria : Staphylococcus aureus (ATCC 25923)(MIC=3.15 ¦Ìg/ml), Bacillus cereus(MIC=3.15 ¦Ìg/ml);##Gram-negative bacteria : E. coli (ATCC 9637)(MIC=12.5 ¦Ìg/ml), Pseudomonas aeruginosa (ATCC BAA-427)(MIC=12.5 ¦Ìg/ml), Klebsiella pneumoniae (ATCC 27736)(MIC=6.25 ¦Ìg/ml);##Fungi : Sporothrix schenckii(MIC=6.25 ¦Ìg/ml), Trichophyton mentagrophytes(MIC=12.5 ¦Ìg/ml), Aspergillus fumigatus(MIC=6.25 ¦Ìg/ml), Candida parapsilosis (ATCC 22019)(MIC=12.5 ¦Ìg/ml)"	[Ref.25069749] 0% hemolysis at 80 ¦Ìg/ml against human red blood cells	Linear	Free	Amidation	None	"Mixed(4, 5, 8 is D)"	"[Ref.25069749] The cell viability of murine fibroblast cells (3T3) is 84.8%, 83.4%, 76.9%, 72.1% and 62.8% at peptide concentrations of 1.5, 3, 4.5, 6 and 9 ¦ÌM."	Not found	25069749	Amino Acids.?2014 Nov;46(11):2531-43. doi: 10.1007/s00726-014-1802-3.	"Ahmad A, Azmi S, Srivastava S, Kumar A, Tripathi JK, Mishra NN, Shukla PK, Ghosh JK"	Design and characterization of short antimicrobial peptides using leucine zipper templates with selectivity towards microorganisms
DRAMP21113	LRRPPRWPRRLLRR	14	PSA (Derived from SLZP)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Sporothrix schenckii, Trichophyton mentagrophytes, Aspergillus fumigatus, Candida parapsilosis"	"[Ref.25069749] Gram-positive bacteria : Staphylococcus aureus (ATCC 25923)(MIC=12.5 ¦Ìg/ml), Bacillus cereus(MIC>100 ¦Ìg/ml);##Gram-negative bacteria : E. coli (ATCC 9637)(MIC=25 ¦Ìg/ml), Pseudomonas aeruginosa (ATCC BAA-427)(MIC=100 ¦Ìg/ml), Klebsiella pneumoniae (ATCC 27736)(MIC=12.5 ¦Ìg/ml);##Fungi : Sporothrix schenckii(MIC=100 ¦Ìg/ml), Trichophyton mentagrophytes(MIC>100 ¦Ìg/ml), Aspergillus fumigatus(MIC>100 ¦Ìg/ml), Candida parapsilosis (ATCC 22019)(MIC>100 ¦Ìg/ml)"	[Ref.25069749] 0% hemolysis at 80 ¦Ìg/ml against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.25069749] The cell viability of murine fibroblast cells (3T3) is 100%, 100%, 100%, 99.9%, 84.8% and 82.1% at peptide concentrations of 1.5, 3, 4.5, 6 and 9 ¦ÌM."	Not found	25069749	Amino Acids.?2014 Nov;46(11):2531-43. doi: 10.1007/s00726-014-1802-3.	"Ahmad A, Azmi S, Srivastava S, Kumar A, Tripathi JK, Mishra NN, Shukla PK, Ghosh JK"	Design and characterization of short antimicrobial peptides using leucine zipper templates with selectivity towards microorganisms
DRAMP21110	LRRLLRWLRRLLRR	14	SLZP (De novo synthesis)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Sporothrix schenckii, Trichophyton mentagrophytes, Aspergillus fumigatus, Candida parapsilosis"	"[Ref.25069749] Gram-positive bacteria : Staphylococcus aureus (ATCC 25923)(MIC=1.56 ¦Ìg/ml), Bacillus cereus(MIC=3.15 ¦Ìg/ml);##Gram-negative bacteria : E. coli (ATCC 9637)(MIC=25 ¦Ìg/ml), Pseudomonas aeruginosa (ATCC BAA-427)(MIC=25 ¦Ìg/ml), Klebsiella pneumoniae (ATCC 27736)(MIC=3.15 ¦Ìg/ml);##Fungi : Sporothrix schenckii(MIC=3.15 ¦Ìg/ml), Trichophyton mentagrophytes(MIC=6.25 ¦Ìg/ml), Aspergillus fumigatus(MIC=6.25 ¦Ìg/ml), Candida parapsilosis (ATCC 22019)(MIC=6.25 ¦Ìg/ml)"	"[Ref.25069749] 15% hemolysis at 10 ¦Ìg/ml , 25% hemolysis at 20 ¦Ìg/ml , 30% hemolysis at 30 ¦Ìg/ml , 40% hemolysis at 40 ¦Ìg/ml , 50% hemolysis at 50 ¦Ìg/ml , 55% hemolysis at 60 ¦Ìg/ml , 70% hemolysis at 70 ¦Ìg/ml , 80% hemolysis at 80¦Ìg/ml against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.25069749] The cell viability of murine fibroblast cells (3T3) is 85.9%, 77.5%, 73.7%, 50.0%, 23.7% and 0% at peptide concentrations of 1.5, 3, 4.5, 6 and 9 ¦ÌM."	Not found	25069749	Amino Acids.?2014 Nov;46(11):2531-43. doi: 10.1007/s00726-014-1802-3.	"Ahmad A, Azmi S, Srivastava S, Kumar A, Tripathi JK, Mishra NN, Shukla PK, Ghosh JK"	Design and characterization of short antimicrobial peptides using leucine zipper templates with selectivity towards microorganisms
DRAMP21109	GIGGALLSAKAALGLAKGLAEHFAN	25	"FPA-Bombinin-BO (toads, amphibians, animals)"	No entry found	Not found	Not found	"Asian bombinid toad species, Bombina orientalis"	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.25056849] Gram-positive bacteria : Staphylococcus aureus(MIC=7 ¦ÌM, MBC=14 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=14 ¦ÌM, MBC=14 ¦ÌM);##Fungi : Candida albicans(MIC=7 ¦ÌM, MBC=14 ¦ÌM)"	[Ref.25056849] 100% hemolysis at 125 mg/L against horse red blood cells	Linear	Free	Amidation	None	L	[Ref.25056849] No cytotoxicity information found	Not found	25056849	Chem Biol Drug Des.?2015 Mar;85(3):259-67. doi: 10.1111/cbdd.12396.	"Xiaojuan Hou, Qiang Du, Renjie Li, Mei Zhou, Hui Wang, Lei Wang, Can Guo, Tianbao Chen and Chris Shaw"	"Feleucin-BO1: A Novel Antimicrobial Non-Apeptide Amide from the Skin Secretion of the Toad, Bombina orientalis, and Design of a Potent Broad-Spectrum Synthetic Analogue, Feleucin-K3"
DRAMP21108	FLKLLKKLL	9	Feleucin-K3 (Derived from Feleucin-BO1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	"In F-K3, these latter residues are substituted with Lys (K) residues, whose side-chains occupied the same positions, producing a model cationic amphipathic character in this analogue."	None	Function: Antibacterial activity against Gram-positive bacteria	"[Ref.25056849] Gram-positive bacteria : Staphylococcus aureus(MIC=34 ¦ÌM, MBC=128 ¦ÌM)"	[Ref.25056849] 100% hemolysis at >250 mg/L against horse red blood cells	Linear	Free	Amidation	None	L	[Ref.25056849] No cytotoxicity information found	Not found	25056849	Chem Biol Drug Des.?2015 Mar;85(3):259-67. doi: 10.1111/cbdd.12396.	"Xiaojuan Hou, Qiang Du, Renjie Li, Mei Zhou, Hui Wang2, Lei Wang2, Can Guo, Tianbao Chen and Chris Shaw"	"Feleucin-BO1: A Novel Antimicrobial Non-Apeptide Amide from the Skin Secretion of the Toad, Bombina orientalis, and Design of a Potent Broad-Spectrum Synthetic Analogue, Feleucin-K3"
DRAMP21104	GIGGALLNVGKVALKGLAKGLAEHFAN	27	"Feleucin-2 (toads, amphibians, animals)"	X5JB11?	Belongs to the?bombinin family.	feleucin-2	Bombina variegata (Yellow-bellied toad)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.25003126] Gram-positive bacteria : Staphylococcus aureus(MIC=8 mg/L, MBC=32 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=32 mg/L, MBC=32 mg/L);##Fungi : Candida albicans(MIC=32 mg/L, MBC=32 mg/L)"	[Ref.25003126] 100% hemolysis at 64 mg/L against horse red blood cells	Linear	Free	Amidation	None	L	[Ref.25003126] No cytotoxicity information found	Not found	25003126	Biomed Res Int. 2014;2014:671362. doi: 10.1155/2014/671362.	"Bing Bai, Xiaojuan Hou, Lei Wang, Lilin Ge, Yu Luo, Chengbang Ma, Mei Zhou, Jinao Duan, Tianbao Chen, and Chris Shaw"	Feleucins: Novel Bombinin Precursor-Encoded Nonapeptide Amides from the Skin Secretion of Bombina variegata
DRAMP21107	FLGLLGSLL	9	"Feleucin-BO1 (toads, amphibians, animals)"	No entry found	Not found	Not found	"Asian bombinid toad species, Bombina orientalis"	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Not found	Alpha helix	"The Phe (F) and Leu (L) residue side-chains are oriented on one side of the peptide In feleucin-BO1, while the short side-chains of the hydrophilic Gly (G) and Ser (S) residues are oriented on the other."	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.25056849] Gram-positive bacteria : Staphylococcus aureus(MIC=3 ¦ÌM, MBC=6 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=12 ¦ÌM, MBC=25 ¦ÌM);##Fungi : Candida albicans(MIC=6 ¦ÌM, MBC=12 ¦ÌM)"	[Ref.25056849] 100% hemolysis at 80 mg/L against horse red blood cells	Linear	Free	Amidation	None	L	[Ref.25056849] No cytotoxicity information found	Not found	25056849	Chem Biol Drug Des.?2015 Mar;85(3):259-67. doi: 10.1111/cbdd.12396.	"Xiaojuan Hou, Qiang Du, Renjie Li, Mei Zhou, Hui Wang, Lei Wang, Can Guo, Tianbao Chen and Chris Shaw"	"Feleucin-BO1: A Novel Antimicrobial Non-Apeptide Amide from the Skin Secretion of the Toad, Bombina orientalis, and Design of a Potent Broad-Spectrum Synthetic Analogue, Feleucin-K3"
DRAMP21222	IirKIirK	8	Control-4D (Derived from IK12-all L)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC=125 mg/L), Staphylococcus aureus(MIC>500 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=31.3 mg/L), Pseudomonas aeruginosa(MIC=125 mg/L);##Fungi : Candida albicans(MIC=62.5 mg/L)"	[Ref.24211081] HC10>2000 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	"Mixed(D-Ile2, D-Arg3, D-Ile6, D-Arg7)"	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21221	iirkiirk	8	Control-all D (Derived from IK12-all L)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC>500 mg/L), Staphylococcus aureus(MIC>500 mg/L);##Gram-negative bacteria : Escherichia coli(MIC>500 mg/L), Pseudomonas aeruginosa(MIC>500 mg/L);##Fungi : Candida albicans(MIC=250 mg/L)"	[Ref.24211081] HC10>2000 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	D	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21219	irvkirvkirvk	12	IK12-all D (Derived from IK12-all L)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC=1.0 mg/L), Staphylococcus aureus(MIC=7.8 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=7.8 mg/L), Pseudomonas aeruginosa(MIC=15.6 mg/L);##Fungi : Candida albicans(MIC=31.3 mg/L)"	[Ref.24211081] HC10>125 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	D	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21220	IIRKIIRK	8	Control-all L (Derived from IK12-all L)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC>500 mg/L), Staphylococcus aureus(MIC>500 mg/L);##Gram-negative bacteria : Escherichia coli(MIC>500 mg/L), Pseudomonas aeruginosa(MIC>500 mg/L);##Fungi : Candida albicans(MIC=500 mg/L)"	[Ref.24211081] HC10>2000 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	L	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21218	IRVKIRVKIRVK	12	IK12-all L (De novo synthesis)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Beta sheet	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC=2.0 mg/L), Staphylococcus aureus(MIC=31.3 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=15.6 mg/L), Pseudomonas aeruginosa(MIC=62.5 mg/L);##Fungi : Candida albicans(MIC=125 mg/L)"	[Ref.24211081] HC10>125 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	L	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21217	IRIkIrIK	8	IK8-2D (Derived from IK8-all L)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC=3.9 mg/L), Staphylococcus aureus(MIC=31.3 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=15.6 mg/L), Pseudomonas aeruginosa(MIC=7.8 mg/L);##Fungi : Candida albicans(MIC=3.9 mg/L)"	[Ref.24211081] HC10=1600 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	"Mixed (D-Lys4, D-Arg6)"	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21215	irik	4	IK4-all D (Derived from IK8-all L)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC>500 mg/L), Staphylococcus aureus(MIC>500 mg/L);##Gram-negative bacteria : Escherichia coli(MIC>500 mg/L), Pseudomonas aeruginosa(MIC>500 mg/L);##Fungi : Candida albicans(MIC>500 mg/L)"	[Ref.24211081] HC10>2000 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	D	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21216	IrIkIrIk	8	IK8-4D (Derived from IK8-all L)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC>500 mg/L), Staphylococcus aureus(MIC>500 mg/L);##Gram-negative bacteria : Escherichia coli(MIC>500 mg/L), Pseudomonas aeruginosa(MIC>500 mg/L);##Fungi : Candida albicans(MIC>500 mg/L)"	[Ref.24211081] HC10>2000 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	"Mixed (D-Arg2, D-Lys4, D-Arg6, D-Lys8)"	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21213	irikirik	8	IK8-all D (Derived from IK8-all L)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC=2.0 mg/L), Staphylococcus aureus(MIC=3.9 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=3.9 mg/L), Pseudomonas aeruginosa(MIC=7.8 mg/L);##Fungi : Candida albicans(MIC=3.9 mg/L)"	[Ref.24211081] HC10=1750 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	D	"[Ref.24211081] The cell viability of mouse alveolar macrophage RAW264.7 cells is 100%, 100%, 95%, 90%, 83.8%, 86.2%, 50%, 8.8% and 5% at peptide concentrations of 1, 2, 4, 8, 16, 31, 62, 100 and 125 mg/L. ##The cell viability of human fetatl lung fibrobl"	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21214	irikir	6	IK6-all D (Derived from IK8-all L)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC=31.3 mg/L), Staphylococcus aureus(MIC=250 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=125 mg/L), Pseudomonas aeruginosa(MIC=250 mg/L);##Fungi : Candida albicans(MIC=15.6 mg/L)"	[Ref.24211081] HC10>2000 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	D	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21212	IRIKIRIK	8	IK8-all L (De novo synthesis)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Beta sheet	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.24211081] Gram-positive bacteria : Staphylococcus epidermidis(MIC=3.9 mg/L), Staphylococcus aureus(MIC=62.5 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=15.6 mg/L), Pseudomonas aeruginosa(MIC=31.3 mg/L);##Fungi : Candida albicans(MIC=3.9 mg/L)"	[Ref.24211081] HC10=2000 mg/L against rabbit red blood cells	Linear	Free	Amidation	None	L	[Ref.24211081] No cytotoxicity information found	Not found	24211081	Biomaterials.?2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.	"Ong ZY,?Cheng J,?Huang Y,?Xu K,?Ji Z,?Fan W,?Yang YY"	"Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic ¦Â-sheet forming peptide amphiphiles."
DRAMP21205	HLNKRVQRELIRWLDWLK	18	AmyI-1-18 (G12R) (Derived from AmyI-1-18)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-negative bacteria. Antifungal activity against Candida albicans	[Ref.27478151] Gram-negative bacteria : Porphyromonas gingivalis(IC50=4.6¡À1.1 ¦ÌM). ##[Ref.26850838] Fungi: Candida albicans(IC50=61¡À8 ¦ÌM)	[Ref.27478151] 2% hemolysis at 50 ¦ÌM against human red blood cells	Linear	Free	Free	None	L	[Ref.27478151##26850840] No cytotoxicity information found	Not found	27478151##26850840	J Biosci Bioeng.?2016 Dec;122(6):652-659. doi: 10.1016/j.jbiosc.2016.05.008. ##Biopolymers. 2016 Mar;106(2):219-229. doi: 10.1002/bip.22819.	"Taniguchi M, Ochiai A, Takahashi K, Nakamichi SI, Nomoto T, Saitoh E, Kato T, Tanaka T"	"Antimicrobial?activity against Porphyromonas gingivalis and mechanism of action of the cationic octadecapeptide AmyI-1-20 and its amino acid-substituted?analogs. ##Effect of alanine, leucine, and arginine substitution on antimicrobial activity against candida albicans and action mechanism of a cationic octadecapeptide derived from ¦Á-amylase of rice."
DRAMP21207	HLLKRVQRELIGWLDWLK	18	AmyI-1-18 (N3L) (Derived from AmyI-1-18)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-negative bacteria. Antifungal activity against Candida albicans	[Ref.27478151] Gram-negative bacteria : Porphyromonas gingivalis(IC50=2.5¡À0.7 ¦ÌM). ##[Ref.26850838] Fungi: Candida albicans(IC50=58¡À22 ¦ÌM)	[Ref.27478151] 3% hemolysis at 50 ¦ÌM against human red blood cells	Linear	Free	Free	None	L	[Ref.27478151##26850842] No cytotoxicity information found	Not found	27478151##26850842	J Biosci Bioeng.?2016 Dec;122(6):652-659. doi: 10.1016/j.jbiosc.2016.05.008. ##Biopolymers. 2016 Mar;106(2):219-229. doi: 10.1002/bip.22821.	"Taniguchi M, Ochiai A, Takahashi K, Nakamichi SI, Nomoto T, Saitoh E, Kato T, Tanaka T"	"Antimicrobial?activity against Porphyromonas gingivalis and mechanism of action of the cationic octadecapeptide AmyI-1-22 and its amino acid-substituted?analogs. ##Effect of alanine, leucine, and arginine substitution on antimicrobial activity against candida albicans and action mechanism of a cationic octadecapeptide derived from ¦Á-amylase of rice."
DRAMP21206	HLNKRVQRELIGWLRWLK	18	AmyI-1-18 (D15R) (Derived from AmyI-1-18)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-negative bacteria. Antifungal activity against Candida albicans	[Ref.27478151] Gram-negative bacteria : Porphyromonas gingivalis(IC50=11¡À1 ¦ÌM). ##[Ref.26850838] Fungi: Candida albicans(IC50=31¡À4 ¦ÌM)	[Ref.27478151] 2% hemolysis at 50 ¦ÌM against human red blood cells	Linear	Free	Free	None	L	[Ref.27478151##26850841] No cytotoxicity information found	Not found	27478151##26850841	J Biosci Bioeng.?2016 Dec;122(6):652-659. doi: 10.1016/j.jbiosc.2016.05.008. ##Biopolymers. 2016 Mar;106(2):219-229. doi: 10.1002/bip.22820.	"Taniguchi M, Ochiai A, Takahashi K, Nakamichi SI, Nomoto T, Saitoh E, Kato T, Tanaka T"	"Antimicrobial?activity against Porphyromonas gingivalis and mechanism of action of the cationic octadecapeptide AmyI-1-21 and its amino acid-substituted?analogs. ##Effect of alanine, leucine, and arginine substitution on antimicrobial activity against candida albicans and action mechanism of a cationic octadecapeptide derived from ¦Á-amylase of rice."
DRAMP21204	HLNKRVQRELRGWLDWLK	18	AmyI-1-18 (I11R) (Derived from AmyI-1-18)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-negative bacteria. Antifungal activity against Candida albicans	[Ref.27478151] Gram-negative bacteria : Porphyromonas gingivalis(IC50=10¡À2 ¦ÌM). ##[Ref.26850838] Fungi: Candida albicans(IC50=62¡À2 ¦ÌM)	[Ref.27478151] 1% hemolysis at 50 ¦ÌM against human red blood cells	Linear	Free	Free	None	L	[Ref.27478151##26850839] No cytotoxicity information found	Not found	27478151##26850839	J Biosci Bioeng.?2016 Dec;122(6):652-659. doi: 10.1016/j.jbiosc.2016.05.008. ##Biopolymers. 2016 Mar;106(2):219-229. doi: 10.1002/bip.22818.	"Taniguchi M, Ochiai A, Takahashi K, Nakamichi SI, Nomoto T, Saitoh E, Kato T, Tanaka T"	"Antimicrobial?activity against Porphyromonas gingivalis and mechanism of action of the cationic octadecapeptide AmyI-1-19 and its amino acid-substituted?analogs. ##Effect of alanine, leucine, and arginine substitution on antimicrobial activity against candida albicans and action mechanism of a cationic octadecapeptide derived from ¦Á-amylase of rice."
DRAMP21203	HLNKRVQRELIGWLDWLK	18	"AmyI-1-18 (Oryza sativa L., Angiospermae, Plants)"	P17654	Belongs to the?glycosyl hydrolase 13 family.	AMY1.1	Oryza sativa subsp. japonica (Rice)	"Antimicrobial, Antibacterial, Anti-Gram-, Antifungal"	Protein level	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-negative bacteria. Antifungal activity gaginst Candida albicans. Important for breakdown of endosperm starch during germination.	[Ref.27478151] Gram-negative bacteria : Porphyromonas gingivalis(IC50=13¡À3 ¦ÌM). ##[Ref.26850838] Fungi: Candida albicans(IC50=64¡À2 ¦ÌM)	[Ref.27478151] 0.1% hemolysis at 100 ¦ÌM against human red blood cells	Linear	Free	Free	None	L	[Ref.27478151##26850838] No cytotoxicity information found	Not found	27478151##26850838	J Biosci Bioeng.?2016 Dec;122(6):652-659. doi: 10.1016/j.jbiosc.2016.05.008. ##Biopolymers. 2016 Mar;106(2):219-229. doi: 10.1002/bip.22817.	"Taniguchi M, Ochiai A, Takahashi K, Nakamichi SI, Nomoto T, Saitoh E, Kato T, Tanaka T"	"Antimicrobial?activity against Porphyromonas gingivalis and mechanism of action of the cationic octadecapeptide AmyI-1-18 and its amino acid-substituted?analogs. ##Effect of alanine, leucine, and arginine substitution on antimicrobial activity against candida albicans and action mechanism of a cationic octadecapeptide derived from ¦Á-amylase of rice."
DRAMP21202	FKKLKKLFKKILKLK	15	HPA3NT3-analog (Derived from HPA3NT3)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Trichosporon beigelli"	"[Ref.19642077] Gram-positive bacteria : Staphylococcus aureus(MIC=8 ¦ÌM), Bacillus subtilis(MIC=8 ¦ÌM), Listeria monocytogenes(MIC=4 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=8 ¦ÌM), Salmonella typhimurium(MIC=1 ¦ÌM), Pseudomonas aeruginosa(MIC=2 ¦ÌM);##Fungi : Candida albicans(MIC=4-8 ¦ÌM), Trichosporon beigelli(MIC=1 ¦ÌM)"	"[Ref.19642077] 0% hemolysis at 100 ¦ÌM , 3% hemolysis at 200 ¦ÌM against human red blood cells"	Linear	Free	Amidation	None	L	[Ref.19642077] No cytotoxicity information found.	Not found	19642077	J Pept Sci.?2009 Sep;15(9):589-94. doi: 10.1002/psc.1155.	"Gopal R, Park SC, Ha KJ, Cho SJ, Kim SW, Song PI, Nah JW, Park Y, Hahm KS"	Effect of Leucine and Lysine substitution on the antimicrobial activity and evaluation of the mechanism of the HPA3NT3 analog peptide.
DRAMP21187	WLRAFRRLVRRLARLLRR	18	WRL4 (Derived from leucocin A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix, beta sheet, turn"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.28002968] Gram-positive bacteria : Staphylococcus aureus 29213(MIC=6.65 ¦ÌM), Staphylococcus aureus 1.160(MIC=1.66 ¦ÌM), Listeria monocytogenes 21662(MIC=3.32 ¦ÌM), Listeria monocytogenes 21633(MIC=3.32 ¦ÌM), Bacillus cereus 63301(MIC=53.18 ¦ÌM), Micrococcus luteus 28001(MIC=13.29 ¦ÌM), Bacillus pumilus 63202(MIC=26.59 ¦ÌM), Pseudomonas fluorescens 21620(MIC=53.18 ¦ÌM), MRSA 43300(MIC=3.32 ¦ÌM);##Gram-negative bacteria : Escherichia coli O157 : H7 21530(MIC=3.32 ¦ÌM), Escherichia coli 25922(MIC=13.29 ¦ÌM), Escherichia coli 35150(MIC=26.59 ¦ÌM), Salmonella paratyphi-A 20501(MIC=6.65 ¦ÌM), Salmonella paratyphi paratyphi-B 21495(MIC=3.32 ¦ÌM), Salmonella paratyphi paratyphi-C 21512(MIC=6.65 ¦ÌM), Shigella flexneri 51571(MIC=1.66 ¦ÌM), Salmonella choleraesuis 13312(MIC=13.29 ¦ÌM), Salmonella typhimurium 51005(MIC>53.18 ¦ÌM), Salmonella enteritidis 21527(MIC>53.28 ¦ÌM), Vibrio parahemolyticus 21617(MIC=6.65 ¦ÌM);##Fungi : Candida albicans 10231(MIC=26.59 ¦ÌM)"	[Ref.28002968] MHC10=53.18 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.28002968] The cell viability of RAW264.7 cells induced by WRL4 is 91.27%, 90.42%, 81.13%, 73.24%, 70.14%, 69.30%, 56.62%, 51.27% and 48.25% at peptide concentrations of 0.25, 0.5, 1, 2, 4, 8, 16, 32 and 64 ¦ÌM."	Not found	28002968	J Med Chem.?2016 Dec 22;59(24):10946-10962. doi: 10.1021/acs.jmedchem.6b00922.	"Ma Z, Yang J, Han J, Gao L, Liu H, Lu Z, Zhao H, Bie X"	Insights into the?Antimicrobial?Activity and Cytotoxicity of Engineered ¦Á-Helical?PeptideAmphiphiles.
DRAMP21186	WLRAFRRLVRRLARGLRR	18	WRL3 (Derived from leucocin A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix, beta sheet, turn"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.28002968] Gram-positive bacteria : Staphylococcus aureus 29213(MIC=0.43 ¦ÌM), Staphylococcus aureus 1.160(MIC=0.43 ¦ÌM), Listeria monocytogenes 21662(MIC=0.21 ¦ÌM), Listeria monocytogenes 21633(MIC=0.21 ¦ÌM), Bacillus cereus 63301(MIC=0.85 ¦ÌM), Micrococcus luteus 28001(MIC=0.43 ¦ÌM), Bacillus pumilus 63202(MIC=0.85 ¦ÌM), Pseudomonas fluorescens 21620(MIC=0.43 ¦ÌM), MRSA 43300(MIC=0.85 ¦ÌM);##Gram-negative bacteria : Escherichia coli O157 : H7 21530(MIC=0.85 ¦ÌM), Escherichia coli 25922(MIC=1.70 ¦ÌM), Escherichia coli 35150(MIC=1.70 ¦ÌM), Salmonella paratyphi-A 20501(MIC=0.43 ¦ÌM), Salmonella paratyphi paratyphi-B 21495(MIC=0.85 ¦ÌM), Salmonella paratyphi paratyphi-C 21512(MIC=0.43 ¦ÌM), Shigella flexneri 51571(MIC=0.43 ¦ÌM), Salmonella choleraesuis 13312(MIC=1.70 ¦ÌM), Salmonella typhimurium 51005(MIC=6.81 ¦ÌM), Salmonella enteritidis 21527(MIC=6.81 ¦ÌM), Vibrio parahemolyticus 21617(MIC=1.70 ¦ÌM);##Fungi : Candida albicans 10231(MIC=3.40 ¦ÌM)"	[Ref.28002968] MHC10=27.22 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.28002968] The cell viability of RAW264.7 cells induced by WRL3 is 98.31%, 95.21%, 92.96%, 90.70%, 89.30%, 89.01%, 76.90%, 48.45% and 40.73% at peptide concentrations of 0.25, 0.5, 1, 2, 4, 8, 16, 32 and 64 ¦ÌM."	Not found	28002968	J Med Chem.?2016 Dec 22;59(24):10946-10962. doi: 10.1021/acs.jmedchem.6b00922.	"Ma Z, Yang J, Han J, Gao L, Liu H, Lu Z, Zhao H, Bie X"	Insights into the?Antimicrobial?Activity and Cytotoxicity of Engineered ¦Á-Helical?PeptideAmphiphiles.
DRAMP21185	WGRAFRRLVRRLARGLRR	18	WRL2 (Derived from leucocin A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix, beta sheet, turn"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.28002968] Gram-positive bacteria : Staphylococcus aureus 29213(MIC=3.49 ¦ÌM), Staphylococcus aureus 1.160(MIC=1.74 ¦ÌM), Listeria monocytogenes 21662(MIC=1.74 ¦ÌM), Listeria monocytogenes 21633(MIC=1.74 ¦ÌM), Bacillus cereus 63301(MIC=55.78 ¦ÌM), Micrococcus luteus 28001(MIC=27.89 ¦ÌM), Bacillus pumilus 63202(MIC=55.78 ¦ÌM), Pseudomonas fluorescens 21620(MIC=55.78 ¦ÌM), MRSA 43300(MIC=6.97 ¦ÌM);##Gram-negative bacteria : Escherichia coli O157 : H7 21530(MIC=6.97 ¦ÌM), Escherichia coli 25922(MIC=27.89 ¦ÌM), Escherichia coli 35150(MIC=13.94 ¦ÌM), Salmonella paratyphi-A 20501(MIC=3.49 ¦ÌM), Salmonella paratyphi paratyphi-B 21495(MIC=6.97 ¦ÌM), Salmonella paratyphi paratyphi-C 21512(MIC=3.49 ¦ÌM), Shigella flexneri 51571(MIC=3.49 ¦ÌM), Salmonella choleraesuis 13312(MIC=13.94 ¦ÌM), Salmonella typhimurium 51005(MIC=13.94 ¦ÌM), Salmonella enteritidis 21527(MIC>55.78 ¦ÌM), Vibrio parahemolyticus 21617(MIC=13.94 ¦ÌM);##Fungi : Candida albicans 10231(MIC=13.94 ¦ÌM)"	[Ref.28002968] MHC10>55.78 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.28002968] The cell viability of RAW264.7 cells induced by WRL2 is 87.32%, 85.35%, 81.13%, 79.15%, 78.87%, 78.03%, 76.34%, 69.86% and 64.79% at peptide concentrations of 0.25, 0.5, 1, 2, 4, 8, 16, 32 and 64 ¦ÌM."	Not found	28002968	J Med Chem.?2016 Dec 22;59(24):10946-10962. doi: 10.1021/acs.jmedchem.6b00922.	"Ma Z, Yang J, Han J, Gao L, Liu H, Lu Z, Zhao H, Bie X"	Insights into the?Antimicrobial?Activity and Cytotoxicity of Engineered ¦Á-Helical?PeptideAmphiphiles.
DRAMP21184	WGRAFRRGVRRLARGGRR	18	WR7 (Derived from leucocin A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix, beta sheet, turn"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.28002968] Gram-positive bacteria : Staphylococcus aureus 29213(MIC=14.66 ¦ÌM), Staphylococcus aureus 1.160(MIC=7.33 ¦ÌM), Listeria monocytogenes 21662(MIC=7.33 ¦ÌM), Listeria monocytogenes 21633(MIC=7.33 ¦ÌM), Bacillus cereus 63301(MIC=14.66 ¦ÌM), Micrococcus luteus 28001(MIC=7.33 ¦ÌM), Bacillus pumilus 63202(MIC>58.64 ¦ÌM), Pseudomonas fluorescens 21620(MIC=29.32 ¦ÌM), MRSA 43300(MIC=14.66 ¦ÌM);##Gram-negative bacteria : Escherichia coli O157 : H7 21530(MIC=3.67 ¦ÌM), Escherichia coli 25922(MIC=14.66 ¦ÌM), Escherichia coli 35150(MIC=29.32 ¦ÌM), Salmonella paratyphi-A 20501(MIC=7.33 ¦ÌM), Salmonella paratyphi paratyphi-B 21495(MIC=3.67 ¦ÌM), Salmonella paratyphi paratyphi-C 21512(MIC=7.33 ¦ÌM), Shigella flexneri 51571(MIC=7.33 ¦ÌM), Salmonella choleraesuis 13312(MIC=14.66 ¦ÌM), Salmonella typhimurium 51005(MIC>58.64 ¦ÌM), Salmonella enteritidis 21527(MIC>58.64 ¦ÌM), Vibrio parahemolyticus 21617(MIC=29.32 ¦ÌM);##Fungi : Candida albicans 10231(MIC=29.32 ¦ÌM)"	[Ref.28002968] MHC10>58.64 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.28002968] The cell viability of RAW264.7 cells induced by WR7 is 97.46%, 94.65%, 89.01%, 82.25%, 81.41%, 80.85%, 78.59%, 76.06% and 74.80% at peptide concentrations of 0.25, 0.5, 1, 2, 4, 8, 16, 32 and 64 ¦ÌM."	Not found	28002968	J Med Chem.?2016 Dec 22;59(24):10946-10962. doi: 10.1021/acs.jmedchem.6b00922.	"Ma Z, Yang J, Han J, Gao L, Liu H, Lu Z, Zhao H, Bie X"	Insights into the?Antimicrobial?Activity and Cytotoxicity of Engineered ¦Á-Helical?PeptideAmphiphiles.
DRAMP21183	WGRAFSRGVRRLARGGRG	18	WR5 (Derived from leucocin A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix, beta sheet, turn"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.28002968] Gram-positive bacteria : Staphylococcus aureus 29213(MIC=31.77 ¦ÌM), Staphylococcus aureus 1.160(MIC=15.89 ¦ÌM), Listeria monocytogenes 21662(MIC=15.89 ¦ÌM), Listeria monocytogenes 21633(MIC=31.77 ¦ÌM), Bacillus cereus 63301(MIC>63.54 ¦ÌM), Micrococcus luteus 28001(MIC>63.54 ¦ÌM), Bacillus pumilus 63202(MIC>63.54 ¦ÌM), Pseudomonas fluorescens 21620(MIC>63.54 ¦ÌM), MRSA 43300(MIC>63.54 ¦ÌM);##Gram-negative bacteria : Escherichia coli O157 : H7 21530(MIC=7.94 ¦ÌM), Escherichia coli 25922(MIC=31.77 ¦ÌM), Escherichia coli 35150(MIC=31.77 ¦ÌM), Salmonella paratyphi-A 20501(MIC=15.89 ¦ÌM), Salmonella paratyphi paratyphi-B 21495(MIC=15.89 ¦ÌM), Salmonella paratyphi paratyphi-C 21512(MIC=15.89 ¦ÌM), Shigella flexneri 51571(MIC=15.89 ¦ÌM), Salmonella choleraesuis 13312(MIC=15.89 ¦ÌM), Salmonella typhimurium 51005(MIC>63.54 ¦ÌM), Salmonella enteritidis 21527(MIC>63.54 ¦ÌM), Vibrio parahemolyticus 21617(MIC>63.54 ¦ÌM);##Fungi : Candida albicans 10231(MIC>63.54 ¦ÌM)"	[Ref.28002968] MHC10>63.54 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.28002968] The cell viability of RAW264.7 cells induced by WR5 is 98.59%, 97.46%, 96.06%, 96.09%, 92.96%, 91.83%, 89.58%, 87.32% and 85.48% at peptide concentrations of 0.25, 0.5, 1, 2, 4, 8, 16, 32 and 64 ¦ÌM."	Not found	28002968	J Med Chem.?2016 Dec 22;59(24):10946-10962. doi: 10.1021/acs.jmedchem.6b00922.	"Ma Z, Yang J, Han J, Gao L, Liu H, Lu Z, Zhao H, Bie X"	Insights into the?Antimicrobial?Activity and Cytotoxicity of Engineered ¦Á-Helical?PeptideAmphiphiles.
DRAMP21182	WGRAFSAGVHRLARGGRG	18	WR3 (Derived from leucocin A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix, beta sheet, turn"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.28002968] Gram-positive bacteria : Staphylococcus aureus 29213(MIC>67.01 ¦ÌM), Staphylococcus aureus 1.160(MIC>67.01 ¦ÌM), Listeria monocytogenes 21662(MIC=33.50 ¦ÌM), Listeria monocytogenes 21633(MIC=67.01 ¦ÌM), Bacillus cereus 63301(MIC>67.01 ¦ÌM), Micrococcus luteus 28001(MIC>67.01 ¦ÌM), Bacillus pumilus 63202(MIC>67.01 ¦ÌM), Pseudomonas fluorescens 21620(MIC>67.01 ¦ÌM), MRSA 43300(MIC>67.01 ¦ÌM);##Gram-negative bacteria : Escherichia coli O157 : H7 21530(MIC=16.75 ¦ÌM), Escherichia coli 25922(MIC>67.01 ¦ÌM), Escherichia coli 35150(MIC>67.01 ¦ÌM), Salmonella paratyphi-A 20501(MIC=33.50 ¦ÌM), Salmonella paratyphi paratyphi-B 21495(MIC>67.01 ¦ÌM), Salmonella paratyphi paratyphi-C 21512(MIC>67.01 ¦ÌM), Shigella flexneri 51571(MIC>67.01 ¦ÌM), Salmonella choleraesuis 13312(MIC=33.50 ¦ÌM), Salmonella typhimurium 51005(MIC>67.01 ¦ÌM), Salmonella enteritidis 21527(MIC>67.01 ¦ÌM), Vibrio parahemolyticus 21617(MIC>67.01 ¦ÌM);##Fungi : Candida albicans 10231(MIC>67.01 ¦ÌM)"	[Ref.28002968] MHC10>67.01 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.28002968] The cell viability of RAW264.7 cells induced by WR3 is 100%, 98.87%, 92.11%, 90.42%, 90.42%, 88.45%, 87.61%, 87.89% and 87.22% at peptide concentrations of 0.25, 0.5, 1, 2, 4, 8, 16, 32 and 64 ¦ÌM."	Not found	28002968	J Med Chem.?2016 Dec 22;59(24):10946-10962. doi: 10.1021/acs.jmedchem.6b00922.	"Ma Z, Yang J, Han J, Gao L, Liu H, Lu Z, Zhao H, Bie X"	Insights into the?Antimicrobial?Activity and Cytotoxicity of Engineered ¦Á-Helical?PeptideAmphiphiles.
DRAMP21181	WGRAFSAGVHRLANGGNG	18	WR1 (Derived from leucocin A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix, beta sheet, turn"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.28002968] Gram-positive bacteria : Staphylococcus aureus 29213(MIC>70.09s ¦ÌM), Staphylococcus aureus 1.160(MIC=70.09 ¦ÌM), Listeria monocytogenes 21662(MIC>70.09 ¦ÌM), Listeria monocytogenes 21633(MIC>70.09 ¦ÌM), Bacillus cereus 63301(MIC>70.09 ¦ÌM), Micrococcus luteus 28001(MIC>70.09 ¦ÌM), Bacillus pumilus 63202(MIC>70.09 ¦ÌM), Pseudomonas fluorescens 21620(MIC>70.09 ¦ÌM), MRSA 43300(MIC>70.09 ¦ÌM);##Gram-negative bacteria : Escherichia coli O157 : H7 21530(MIC>70.09 ¦ÌM), Escherichia coli 25922(MIC>70.09 ¦ÌM), Escherichia coli 35150(MIC>70.09 ¦ÌM), Salmonella paratyphi-A 20501(MIC>70.09 ¦ÌM), Salmonella paratyphi paratyphi-B 21495(MIC>70.09 ¦ÌM), Salmonella paratyphi paratyphi-C 21512(MIC>70.09 ¦ÌM), Shigella flexneri 51571(MIC>70.09 ¦ÌM), Salmonella choleraesuis 13312(MIC>70.09 ¦ÌM), Salmonella typhimurium 51005(MIC>70.09 ¦ÌM), Salmonella enteritidis 21527(MIC>70.09 ¦ÌM), Vibrio parahemolyticus 21617(MIC>70.09 ¦ÌM);##Fungi : Candida albicans 10231(MIC>70.09 ¦ÌM)"	[Ref.28002968] MHC10>70.09 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.28002968] The cell viability of RAW264.7 cells induced by WR1 is 99.44%, 96.62%, 95.21%, 94.08%, 92.96%, 92.99%, 92.68%, 87.04% and 77.58% at peptide concentrations of 0.25, 0.5, 1, 2, 4, 8, 16, 32 and 64 ¦ÌM."	Not found	28002968	J Med Chem.?2016 Dec 22;59(24):10946-10962. doi: 10.1021/acs.jmedchem.6b00922.	"Ma Z, Yang J, Han J, Gao L, Liu H, Lu Z, Zhao H, Bie X"	Insights into the?Antimicrobial?Activity and Cytotoxicity of Engineered ¦Á-Helical?PeptideAmphiphiles.
DRAMP21180	WGEAFSAGVHRLANGGNG	18	WG18 (Derived from leucocin A)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"Random coil, alpha helix, beta sheet, turn"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.28002968] Gram-positive bacteria : Staphylococcus aureus 29213(MIC>71.15 ¦ÌM), Staphylococcus aureus 1.160(MIC>71.15 ¦ÌM), Listeria monocytogenes 21662(MIC>71.15 ¦ÌM), Listeria monocytogenes 21633(MIC>71.15 ¦ÌM), Bacillus cereus 63301(MIC>71.15 ¦ÌM), Micrococcus luteus 28001(MIC>71.15 ¦ÌM), Bacillus pumilus 63202(MIC>71.15 ¦ÌM), Pseudomonas fluorescens 21620(MIC>71.15 ¦ÌM), MRSA 43300(MIC>71.15 ¦ÌM);##Gram-negative bacteria : Escherichia coli O157 : H7 21530(MIC>71.15 ¦ÌM), Escherichia coli 25922(MIC>71.15 ¦ÌM), Escherichia coli 35150(MIC>71.15 ¦ÌM), Salmonella paratyphi-A 20501(MIC>71.15 ¦ÌM), Salmonella paratyphi paratyphi-B 21495(MIC>71.15 ¦ÌM), Salmonella paratyphi paratyphi-C 21512(MIC>71.15 ¦ÌM), Shigella flexneri 51571(MIC>71.15 ¦ÌM), Salmonella choleraesuis 13312(MIC>71.15 ¦ÌM), Salmonella typhimurium 51005(MIC>71.15 ¦ÌM), Salmonella enteritidis 21527(MIC>71.15 ¦ÌM), Vibrio parahemolyticus 21617(MIC>71.15 ¦ÌM);##Fungi : Candida albicans 10231(MIC>71.15 ¦ÌM)"	[Ref.28002968] MHC10>71.15 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.28002968] The cell viability of RAW264.7 cells induced by WG18 is 98.87%, 94.93%, 93.52%, 90.14%, 85.35%, 83.10%, 80.56%, 75.77% and 73.62% at peptide concentrations of 0.25, 0.5, 1, 2, 4, 8, 16, 32 and 64 ¦ÌM."	Not found	28002968	J Med Chem.?2016 Dec 22;59(24):10946-10962. doi: 10.1021/acs.jmedchem.6b00922.	"Ma Z, Yang J, Han J, Gao L, Liu H, Lu Z, Zhao H, Bie X"	Insights into the?Antimicrobial?Activity and Cytotoxicity of Engineered ¦Á-Helical?PeptideAmphiphiles.
DRAMP21179	GILSSLWKKPKKIIAK	16	HYL-26 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC>100 ¦ÌM), Staphylococcus epidermidis(MIC>100 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC>100¦ÌM), Pseudomonas aeruginosa 5482(MIC=98 ¦ÌM);##Fungi : Candida albicans(MIC>100 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21178	GILSSLWKKLKKWIAK	16	HYL-25 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=2.5 ¦ÌM), Staphylococcus epidermidis(MIC=1.6 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=2.5 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=13 ¦ÌM);##Fungi : Candida albicans(MIC=13 ¦ÌM)"	[Ref.26998557] LC50=57 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21177	GILSSLLKKLKKWIAK	16	HYL-24 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=8 ¦ÌM), Staphylococcus epidermidis(MIC=1.6 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=4 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=8 ¦ÌM);##Fungi : Candida albicans(MIC=16 ¦ÌM)"	[Ref.26998557] LC50=115 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21176	GILSSLLKKWKKIIAK	16	HYL-23 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=20 ¦ÌM), Staphylococcus epidermidis(MIC=2.7 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=7.5 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=5 ¦ÌM);##Fungi : Candida albicans(MIC=11 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21175	GKLSSLWKKLKKIIAK	16	HYL-22 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=26 ¦ÌM), Staphylococcus epidermidis(MIC=2.5 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=20 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=6.8 ¦ÌM);##Fungi : Candida albicans(MIC=34 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21174	gilsslwkklkkiiak	16	HYL-21 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=6.3 ¦ÌM), Staphylococcus epidermidis(MIC=1.7 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=5 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=6.7 ¦ÌM);##Fungi : Candida albicans(MIC=8 ¦ÌM)"	[Ref.26998557] LC50=191 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	D	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21173	GILSSLWKKLKKIIAK	16	HYL-20 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=5.3 ¦ÌM), Staphylococcus epidermidis(MIC=2 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=3.4 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=5.3 ¦ÌM);##Fungi : Candida albicans(MIC=11 ¦ÌM)"	[Ref.26998557] LC50=197 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21172	GILSSWLKKLKKIIAK	16	HYL-19 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=16 ¦ÌM), Staphylococcus epidermidis(MIC=2 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=11 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=4 ¦ÌM);##Fungi : Candida albicans(MIC=17 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21168	GILKSLLKKLKKIIAK	16	HYL-15 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=17 ¦ÌM), Staphylococcus epidermidis(MIC=2.2 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=10 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=5 ¦ÌM);##Fungi : Candida albicans(MIC=24 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21169	GILSKLLKKLKKIIAK	16	HYL-16 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=23 ¦ÌM), Staphylococcus epidermidis(MIC=1.8 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=18 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=4.5 ¦ÌM);##Fungi : Candida albicans(MIC=45 ¦ÌM)"	[Ref.26998557] LC50>400 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21170	kILSSLLKKLKKIIAK	16	HYL-17 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=32 ¦ÌM), Staphylococcus epidermidis(MIC=1.4 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=16 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=5 ¦ÌM);##Fungi : Candida albicans(MIC=25 ¦ÌM)"	[Ref.26998557] LC50=364 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	Mixed(1 is D)	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21171	GIWSSLLKKLKKIIAK	16	HYL-18 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=20 ¦ÌM), Staphylococcus epidermidis(MIC=1.5 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=1.6 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=6.3 ¦ÌM);##Fungi : Candida albicans(MIC=16 ¦ÌM)"	[Ref.26998557] LC50=165 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21167	gilssllkklkkiiak	16	HYL-13 (Derived from HYL)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=5.7 ¦ÌM), Staphylococcus epidermidis(MIC=3.2 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=4.5 ¦ÌM), Pseudomonas aeruginosa 5482(MIC=4.5 ¦ÌM);##Fungi : Candida albicans(MIC=9 ¦ÌM)"	[Ref.26998557] LC50=333 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	D	[Ref.26998557] No cytotoxicity information found.	Not found	26998557	J Nat Prod.?2016 Apr 22;79(4):1073-83. doi: 10.1021/acs.jnatprod.5b01129.	"Ne?uta O, Hexnerov¨¢ R, Bud¨§?¨ªnsk? M, Slaninov¨¢ J, Bedn¨¢rov¨¢ L, Hadravov¨¢ R, Straka J, Veverka V, ?e?ovsk? V"	Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
DRAMP21244	FLSLIPKLVKKIIKAFK	17	TsAP-S1 (Derived from TsAP-1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Anticancer against H157, H838, MCF-7, PC3 and U251-MG"	"[Ref.23770440] Gram-positive bacteria : Staphylococcus aureus(MIC=2.5 ¦ÌM, MBC=20 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=5 ¦ÌM, MBC=20 ¦ÌM);##Fungi : Candida albicans(MIC=2.5 ¦ÌM, MBC=5 ¦ÌM)"	"[Ref.23770440] 30% hemolysis at 5 ¦ÌM , 85% hemolysis at 10 ¦ÌM , 100% hemolysis at 20 ¦ÌM against horse red blood cells"	Linear	Free	Amidation	None	L	[Ref.23770440] No cytotoxicity information found.	Not found	23770440	Biochimie.?2013 Sep;95(9):1784-94. doi: 10.1016/j.biochi.2013.06.003.	"Guo X,?Ma C,?Du Q,?Wei R,?Wang L,?Zhou M,?Chen T,?Shaw C"	"Two?peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their?antimicrobial?and anticancer activities."
DRAMP21245	FLGMIPKLIKKLIKAFK	17	TsAP-S2 (Derived from TsAP-2)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Alpha helix	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Anticancer against H157, H838, MCF-7, PC3 and U252-MG"	"[Ref.23770440] Gram-positive bacteria : Staphylococcus aureus(MIC=5 ¦ÌM, MBC=20 ¦ÌM);##Gram-negative bacteria : Escherichia coli(MIC=5 ¦ÌM, MBC=40 ¦ÌM);##Fungi : Candida albicans(MIC=2.5 ¦ÌM, MBC=10 ¦ÌM)"	"[Ref.23770440] 30% hemolysis at 5 ¦ÌM , 85% hemolysis at 10 ¦ÌM , 100% hemolysis at 20 ¦ÌM against horse red blood cells"	Linear	Free	Amidation	None	L	[Ref.23770440] No cytotoxicity information found.	Not found	23770440	Biochimie.?2013 Sep;95(9):1784-94. doi: 10.1016/j.biochi.2013.06.003.	"Guo X,?Ma C,?Du Q,?Wei R,?Wang L,?Zhou M,?Chen T,?Shaw C"	"Two?peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their?antimicrobial?and anticancer activities."
DRAMP21251	FLFSLIPSVIAGLVSAIRN	19	"AaeAP1 (Scorpionida, Arachricla, Arthropoda)"	A0A060QQ43?	Not found	AP1	Androctonus aeneas	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria. Antifungal activity against Candida albicans	"[Ref.25626077] Gram-positive bacteria : Staphylococcus aureus(MIC=16 mg/L, MBC=32 mg/L);##Gram-negative bacteria : Escherichia coli(MIC>512 mg/L);##Fungi : Candida albicans(MIC=32 mg/L, MBC=64 mg/L)"	[Ref.25626077] 100% hemolysis at 16 ¦Ìg/ml against horse red blood cells	Linear	Free	Amidation	None	L	[Ref.25626077] No cytotoxicity information found.	Not found	25626077	Toxins (Basel).?2015 Jan 23;7(2):219-37. doi: 10.3390/toxins7020219.	"Du Q,?Hou X,?Wang L,?Zhang Y,?Xi X,?Wang H,?Zhou M,?Duan J,?Wei M,?Chen T,?Shaw C"	"AaeAP1 and AaeAP2: novel antimicrobial peptides from the venom of the scorpion, Androctonus aeneas: structural characterisation, molecular cloning of biosynthetic precursor-encoding cDNAs and engineering of analogues with enhanced antimicrobial and anticancer activities."
DRAMP21252	FLFSLIPSAIAGLVSAIRN	19	"AaeAP2 (Scorpionida, Arachricla, Arthropoda)"	A0A060QMQ0?	Not found	AP2	Androctonus aeneas	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Transcript level	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria. Antifungal activity against Candida albicans	"[Ref.25626077] Gram-positive bacteria : Staphylococcus aureus(MIC=16 mg/L, MBC=16 mg/L);##Gram-negative bacteria : Escherichia coli(MIC>512 mg/L);##Fungi : Candida albicans(MIC=32 mg/L, MBC=64 mg/L)"	[Ref.25626077] 100% hemolysis at 64 ¦Ìg/ml against horse red blood cells	Linear	Free	Amidation	None	L	[Ref.25626077] No cytotoxicity information found.	Not found	25626077	Toxins (Basel).?2015 Jan 23;7(2):219-37. doi: 10.3390/toxins7020219.	"Du Q,?Hou X,?Wang L,?Zhang Y,?Xi X,?Wang H,?Zhou M,?Duan J,?Wei M,?Chen T,?Shaw C"	"AaeAP1 and AaeAP2: novel antimicrobial peptides from the venom of the scorpion, Androctonus aeneas: structural characterisation, molecular cloning of biosynthetic precursor-encoding cDNAs and engineering of analogues with enhanced antimicrobial and anticancer activities."
DRAMP21253	FLFKLIPKAIKGLVKAIRK	19	AaeAP1a (Derived from AaeAP1)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.25626077] Gram-positive bacteria : Staphylococcus aureus(MIC=4 mg/L, MBC=32 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=16 mg/L, MBC=32 mg/L);##Fungi : Candida albicans(MIC=4 mg/L, MBC=16 mg/L)"	[Ref.25626077] 100% hemolysis at 32 ¦Ìg/ml against horse red blood cells	Linear	Free	Amidation	None	L	[Ref.25626077] No cytotoxicity information found.	Not found	25626077	Toxins (Basel).?2015 Jan 23;7(2):219-37. doi: 10.3390/toxins7020219.	"Du Q,?Hou X,?Wang L,?Zhang Y,?Xi X,?Wang H,?Zhou M,?Duan J,?Wei M,?Chen T,?Shaw C"	"AaeAP1 and AaeAP2: novel antimicrobial peptides from the venom of the scorpion, Androctonus aeneas: structural characterisation, molecular cloning of biosynthetic precursor-encoding cDNAs and engineering of analogues with enhanced antimicrobial and anticancer activities."
DRAMP21254	FLFKLIPKVIKGLVKAIRK	19	AaeAP2a (Derived from AaeAP2)	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans	"[Ref.25626077] Gram-positive bacteria : Staphylococcus aureus(MIC=4 mg/L, MBC=32 mg/L);##Gram-negative bacteria : Escherichia coli(MIC=16 mg/L, MBC=32 mg/L);##Fungi : Candida albicans(MIC=4 mg/L, MBC=16 mg/L)"	[Ref.25626077] 100% hemolysis at 64 ¦Ìg/ml against horse red blood cells	Linear	Free	Amidation	None	L	[Ref.25626077] No cytotoxicity information found.	Not found	25626077	Toxins (Basel).?2015 Jan 23;7(2):219-37. doi: 10.3390/toxins7020219.	"Du Q,?Hou X,?Wang L,?Zhang Y,?Xi X,?Wang H,?Zhou M,?Duan J,?Wei M,?Chen T,?Shaw C"	"AaeAP1 and AaeAP2: novel antimicrobial peptides from the venom of the scorpion, Androctonus aeneas: structural characterisation, molecular cloning of biosynthetic precursor-encoding cDNAs and engineering of analogues with enhanced antimicrobial and anticancer activities."
DRAMP21259	MDSFQKIEKIGEGTYGVVYKAKDKVSGRLVALKKIRLENESEGVPSTA	48	"Scolopendin 1 (Centipedes, Arthropoda, Animals)"	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Not found	Not found	None	"Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans, Candida parapsilosis, Trichosporon beigelii"	"[Ref.25209888] Gram-positive bacteria : Staphylococcus aureus ATCC 25923(MIC=5.0 ¡À 4.3 ¦ÌM), Enterococcus faecium ATCC 19434(MIC=10.0 ¡À 8.7 ¦ÌM);##Gram-negative bacteria : Escherichia coli O-157 ATCC 43895(MIC=5.0 ¡À 4.3 ¦ÌM), Pseudomonas aeruginosa ATCC 27853(MIC= 5.0 ¡À 4.3 ¦ÌM);##Fungi : Candida albicans ATCC 90028(MIC=10.0 ¡À 8.7 ¦ÌM), Candida parapsilosis ATCC 22019(MIC= 10.0 ¡À 8.7 ¦ÌM), Trichosporon beigelii KCTC 7707(MIC=20.0 ¡À 17.3 ¦ÌM)"	[Ref.25209888] 0% hemolysis at 80 ¦ÌM against human red blood cells	Linear	Free	Amidation	None	L	[Ref.25209888] No cytotoxicity information found	Not found	25209888	Insect Mol Biol.?2014 Dec;23(6):788-99. doi: 10.1111/imb.12124.	"Choi H,?Hwang JS,?Lee DG"	"Identification of a novel antimicrobial peptide, scolopendin 1, derived from centipede Scolopendra subspinipes mutilans and its antifungal mechanism."
DRAMP21334	SFLTTVKKLVTNLAALAGTVIDTIKCKVTGGCRT	34	"Ranatuerin-2Pb (Frogs, amphibians, animals)"	A0A513ZTP5	Not found	Not found	Lithobates pipiens (Northern leopard frog) (Rana pipiens)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Transcript level	"50% Helix, 7.8% antiparallel, 1.2% parallel, 10.9% turn and 29.8% others in 50% TFE/H2O. ##3.5% Helix, 26.6% antiparallel, 0% parallel, 18.3% turn and"	"Ranatuerin-2Pb might also possess two helical segments at respective N-terminus and C-terminus, and the last two residues are probably included in the helix domain."	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31242693] Gram-positive bacteria:Staphylococcus aureus (MIC=8 ¦ÌM; MBC=8 ¦ÌM), MRSA (MIC=16 ¦ÌM; MBC=32 ¦ÌM), Enterococcus faecalis (MIC>256 ¦ÌM; MBC>256 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=8 ¦ÌM; MBC=8 ¦ÌM), Pseudomonas aeruginosa (MIC>256 ¦ÌM; MBC>256 ¦ÌM);##Fungi: Candida albicans (MIC=8 ¦ÌM; MBC=16 ¦ÌM)"	"[Ref.31242693] 7% hemolysis at 2 ¦ÌM, 23% hemolysis at 8 ¦ÌM, 50% hemolysis at 16 ¦ÌM, 71% hemolysis at 32 ¦ÌM, 100% hemolysis at 64 ¦ÌM on horse erythrocytes."	Linear	Free	Free	None	L	"[Ref.31242693] The IC50 values which represents the inhibitory effect of Ranatuerin-2Pb on the proliferation of NCI-H157, MCF-7, U251MG and PC-3 are 1.453 ¦ÌM, 7.254 ¦ÌM, 2.172 ¦ÌM and 2.251 ¦ÌM. In addtion, Ranatuerin-2Pb showed no inhibitory effect on the proliferation of MDA-MB-435s.  DETAILED DATA: ¢ÙThe cell viabillity of NCI-H157 induced by Ranatuerin-2Pb is 96.2%, 96.9%, 85.6%, 60%, 5% and 4.4% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 100%, 95%, 89.4%, 41.2%, 16.2% and 16.2% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢ÚThe cell viability of MCF-7 induced by Ranatuerin-2Pb is 100.6%, 92.5%, 90%, 99.4%, 36.2% and 11.2% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 100%, 98.1%, 92.5%, 7.5%, 8.7% and 8.7% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢ÛThe cell viability of U251-MG induced by Ranatuerin-2Pb is 100%, 105.6%, 108.1%, 102.5%, 59.4% and 17.5% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 99.4%, 99.4%, 75.6%, 18.7%, 11.9% and 18.1% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢ÜThe cell viability of PC-3 induced by Ranatuerin-2Pb is 108.7%, 112.5%, 84.4%, 80.6%, 28.1% and 16.2% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 110%, 113.1%, 109.4%, 33.1%, 16.9% and 16.2% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢Ý The cell viability of MDA-MB-435S induced by Ranatuerin-2Pb is 96.9%, 88.8%, 96.9%, 88.1%, 100 and 25.6%, while the cell viability induced by Melittin is 100%, 93.1%, 82.5%, 18.8%, 18.8% and 18.1%."	Not found	31242693	Biomolecules. 2019 Jun 25;9(6):249. doi: 10.3390/biom9060249.	"Zhou, XW; Shi, DN; Zhong, RM; Ye, ZM; Ma, CB; Zhou, M; Xi, XP; Wang, L; Chen, TB; Kwok, HF"	Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues
DRAMP21335	SFLTTVKKLVTNLAALAGTVIDTIKCKVTGGC	32	"RPa (Frogs, amphibians, animals)"	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"33.6% Helix, 18.1% antiparallel, 4.3% parallel, 11.4% turn and 32.5% others in 50% TFE/H2O. ##2.4% Helix, 30.6% antiparallel, 0% parallel, 17.3% turn "	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31242693] Gram-positive bacteria:Staphylococcus aureus (MIC=16 ¦ÌM; MBC=32 ¦ÌM), MRSA (MIC=>256 ¦ÌM; MBC>256 ¦ÌM), Enterococcus faecalis (MIC>256 ¦ÌM; MBC>256 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=32 ¦ÌM; MBC=64 ¦ÌM), Pseudomonas aeruginosa (MIC>256 ¦ÌM; MBC>256 ¦ÌM);##Fungi: Candida albicans (MIC>256 ¦ÌM; MBC>256 ¦ÌM)"	"[Ref.31242693] 7% hemolysis at 16 ¦ÌM, 23% hemolysis at 32 ¦ÌM, 50% hemolysis at 64 ¦ÌM, 76% hemolysis at 128 ¦ÌM, 90% hemolysis at 256 ¦ÌM, 100% hemolysis at 512 ¦ÌM on horse erythrocytes."	Linear	Free	Free	None	L	"[Ref.31242693] RPa only possessed inhibitory effect on the proliferation of H157 with the IC value of 5.841 ¦ÌM, while showed no inhibitory effect on the proliferation of MCF-7, U251MG, PC-3 and MDA-MB-435s. DETAILED DATA: ¢ÙThe cell viabillity of NCI-H157 induced by RPa is 97.5%, 94.4%, 92.5%, 71.2%, 40.6% and 4.4% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 100%, 95%, 89.4%, 41.2%, 16.2% and 16.2% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢ÚThe cell viability of MCF-7 induced by RPa is 100.6%, 93.1%, 97.5%, 97.5%, 93.7% and 78.1% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM , while the cell viability induced by Melittin is 100%, 98.1%, 92.5%, 7.5%, 8.7% and 8.7% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢ÛThe cell viability of U251-MG induced by RPa is 100%, 105.6%, 108.1%, 102.5%, 59.4% and 17.5% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 99.4%, 99.4%, 75.6%, 18.7%, 11.9% and 18.1% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM.¢ÜThe cell viability of PC-3 induced by RPb is 108.7%, 104.4%, 92.5%, 92.5%, 82.5% and 24.4% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 110%, 113.1%, 109.4%, 33.1%, 16.9% and 16.2% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢ÝThe cell viability of MDA-MB-435S induced by RPa is 97.5%, 95%, 97.5%, 73.1%, 68.8% and 36.9%, while the cell viability induced by Melittin is 100%, 93.1%, 82.5%, 18.8%, 18.8% and 18.1%."	Not found	31242693	Biomolecules. 2019 Jun 25;9(6):249. doi: 10.3390/biom9060249.	"Zhou, XW; Shi, DN; Zhong, RM; Ye, ZM; Ma, CB; Zhou, M; Xi, XP; Wang, L; Chen, TB; Kwok, HF"	Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues
DRAMP21336	SFLTTVKKLVTNLAAL	16	"RPb (Frogs, amphibians, animals)"	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"49.6% Helix, 7.6% antiparallel, 0% parallel, 9.8% turn and 33% others in 50% TFE/H2O. ##0.3% Helix, 25.4% antiparallel, 0% parallel, 19.4% turn and 55"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31242693] Gram-positive bacteria:Staphylococcus aureus (MIC=8 ¦ÌM; MBC=8 ¦ÌM), MRSA (MIC=16 ¦ÌM; MBC=32 ¦ÌM), Enterococcus faecalis (MIC=32 ¦ÌM; MBC=128 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=16 ¦ÌM; MBC=16 ¦ÌM), Pseudomonas aeruginosa (MIC=64 ¦ÌM; MBC=256 ¦ÌM);##Fungi: Candida albicans (MIC=16 ¦ÌM; MBC=16 ¦ÌM)"	"[Ref.31242693] 7% hemolysis at 16 ¦ÌM, 18% hemolysis at 32 ¦ÌM, 20% hemolysis at 64 ¦ÌM, 40% hemolysis at 128 ¦ÌM, 70% hemolysis at 256 ¦ÌM, 100% hemolysis at 512 ¦ÌM on horse erythrocytes. "	Linear	Free	Amidation	None	L	"[Ref.31242693] RPb only possessed inhibitory effect on the proliferation of H157 with the IC value of 6.856 ¦ÌM, while showed no inhibitory effect on the proliferation of MCF-7, U251MG, PC-3 and MDA-MB-435s. DETAILED DATA: ¢ÙThe cell viabillity of NCI-H157 induced by RPb is 98.7%, 102.5%, 96.9%, 98.1%, 38.1%, 9.4% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 100%, 95%, 89.4%, 41.2%, 16.2% and 16.2% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢ÚThe cell viability of MCF-7 induced by RPb is 100.6%, 92.5%, 90%, 99.4%, 36.2% and 11.2% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, , while the cell viability induced by Melittin is 100%, 98.1%, 92.5%, 7.5%, 8.7% and 8.7% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢ÛThe cell viability of U251-MG induced by RPb is 105%, 103.1%, 109.4%, 102.5%, 105.6% and 13.1% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 99.4%, 99.4%, 75.6%, 18.7%, 11.9% and 18.1% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM.¢ÜThe cell viability of PC-3 induced by RPa is 108.8%, 103.8%, 118.1%, 125.6%, 116.9% and 68.8% at peptide concentrations of 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM, while the cell viability induced by Melittin is 110%, 113.1%, 109.4%, 33.1%, 16.9% and 16.2% at 0.001, 0.01, 0.1, 1, 10, 100 ¦ÌM. ¢ÝThe cell viability of MDA-MB-435S induced by RPa is 98.1%, 95%, 100.6%, 97.5%, 80.6% and 43.1%, while the cell viability induced by Melittin is 100%, 93.1%, 82.5%, 18.8%, 18.8% and 18.1%."	Not found	31242693	Biomolecules. 2019 Jun 25;9(6):249. doi: 10.3390/biom9060249.	"Zhou, XW; Shi, DN; Zhong, RM; Ye, ZM; Ma, CB; Zhou, M; Xi, XP; Wang, L; Chen, TB; Kwok, HF"	Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues
DRAMP21338	FLRALWNVAKSVF	13	[Arg]3-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	23% ¦Á-helix in 60% TFE/Water. ## 0%¦Á-helix in water.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans and Candida tropicalis IOC 4560.	"[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=1.6?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=1.6?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=0.8?¦Ìmol/L), Bacillus subtilis ATCC 6633 (MIC=0.8?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=1.6?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.4?¦Ìmol/L), Enterobacter cloacae ¦Â-12 (MIC=6.3?¦Ìmol/L), Pseudomonas aeruginosa ATCC 27853 (MIC=6.3?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=0.8?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=0.8?¦Ìmol/L)"	"[Ref.31212183] 25% hemolysis at 6.3 ¦Ìmol/L, 65% hemolysis at 25 ¦Ìmol/L, 75% hemolysis at 50 ¦Ìmol/L, 100% hemolysis at 100 ¦Ìmol/L for human red blood cells"	Linear	Free	Amidation	None	L	[Ref.31212183] No cytotoxicity information found	Not found	31212183	Bioorg Chem.?2019 Jun 8;90:103038. doi: 10.1016/j.bioorg.2019.103038.	"Pedron CN,?Ara¨²jo I,?da Silva Junior PI,?Dias da Silva F,?Torres MT,?Oliveira Junior VX"	Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
DRAMP21339	FLGALWRVAKSVF	13	[Arg]7-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	22% ¦Á-helix in 60% TFE/Water. ## 0%¦Á-helix in water.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans and Candida tropicalis IOC 4561.	"[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=1.6?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=1.6?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=0.4?¦Ìmol/L), Bacillus subtilis ATCC 6633 (MIC=0.8?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=1.6?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.2?¦Ìmol/L), Enterobacter cloacae ¦Â-12 (MIC=6.3?¦Ìmol/L), Pseudomonas aeruginosa ATCC 27853 (MIC=6.3?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=0.8?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=0.8?¦Ìmol/L)"	"[Ref.31212183] 10% hemolysis at 6.3 ¦Ìmol/L, 50% hemolysis at 12.5 ¦Ìmol/L, 60% hemolysis at 25 ¦Ìmol/L, 90% hemolysis at 500 ¦Ìmol/L for human red blood cells"	Linear	Free	Amidation	None	L	[Ref.31212183] No cytotoxicity information found	Not found	31212183	Bioorg Chem.?2019 Jun 8;90:103038. doi: 10.1016/j.bioorg.2019.103038.	"Pedron CN,?Ara¨²jo I,?da Silva Junior PI,?Dias da Silva F,?Torres MT,?Oliveira Junior VX"	Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
DRAMP21340	FLGALWNVAKRVF	13	[Arg]11-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	25% ¦Á-helix in 60% TFE/Water. ## 2%¦Á-helix in water.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans and Candida tropicalis IOC 4562.	"[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=1.6?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=1.6?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=0.8?¦Ìmol/L), Bacillus subtilis ATCC 6633 (MIC=0.8?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=1.6?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.2?¦Ìmol/L), Enterobacter cloacae ¦Â-12 (MIC=6.3?¦Ìmol/L), Pseudomonas aeruginosa ATCC 27853 (MIC=12.5?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=0.8?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=0.8?¦Ìmol/L)"	"[Ref.31212183] 25% hemolysis at 6.3 ¦Ìmol/L, 50% hemolysis at 12.5 ¦Ìmol/L, 70% hemolysis at 25 ¦Ìmol/L, 90% hemolysis at 500 ¦Ìmol/L for human red blood cells"	Linear	Free	Amidation	None	L	[Ref.31212183] No cytotoxicity information found	Not found	31212183	Bioorg Chem.?2019 Jun 8;90:103038. doi: 10.1016/j.bioorg.2019.103038.	"Pedron CN,?Ara¨²jo I,?da Silva Junior PI,?Dias da Silva F,?Torres MT,?Oliveira Junior VX"	Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
DRAMP21341	GLGALWNVAKSVF	13	[Gly]1-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	37% ¦Á-helix in 60% TFE/Water. ## 2%¦Á-helix in water.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans and Candida tropicalis IOC 4563.	"[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.8?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=25?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=3.1?¦Ìmol/L), Bacillus subtilis ATCC 6633 (MIC=3.1?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=50?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.4?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=25?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=6.3?¦Ìmol/L)"	"[Ref.31212183] 10% hemolysis at 50 ¦Ìmol/L, 30% hemolysis at 100 ¦Ìmol/L for human red blood cells"	Linear	Free	Amidation	None	L	[Ref.31212183] No cytotoxicity information found	Not found	31212183	Bioorg Chem.?2019 Jun 8;90:103038. doi: 10.1016/j.bioorg.2019.103038.	"Pedron CN,?Ara¨²jo I,?da Silva Junior PI,?Dias da Silva F,?Torres MT,?Oliveira Junior VX"	Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
DRAMP21342	FLGALWNPAKSVF	13	[Pro]8-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	12% ¦Á-helix in 60% TFE/Water. ## 2%¦Á-helix in water.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida tropicalis IOC 4564.	"[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=12.5?¦Ìmol/L), Bacillus subtilis ATCC 6633 (MIC=50?¦Ìmol/L);##Gram-negative bacteria: Serratia marcescens ATCC 4112 (MIC=12.5?¦Ìmol/L);##Fungi: Candida tropicalis IOC 4560 (MIC=50?¦Ìmol/L)"	[Ref.31212183] 0% hemolysis at 100 ¦Ìmol/L for human red blood cells	Linear	Free	Amidation	None	L	[Ref.31212183] No cytotoxicity information found	Not found	31212183	Bioorg Chem.?2019 Jun 8;90:103038. doi: 10.1016/j.bioorg.2019.103038.	"Pedron CN,?Ara¨²jo I,?da Silva Junior PI,?Dias da Silva F,?Torres MT,?Oliveira Junior VX"	Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
DRAMP21343	FLGALWNVLKSVF	13	[Leu]9-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	62% ¦Á-helix in 60% TFE/Water. ## 3%¦Á-helix in water.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans and Candida tropicalis IOC 4565.	"[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.4?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=0.8?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=3.1?¦Ìmol/L), Bacillus subtilis ATCC 6633 (MIC=0.8?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=0.8?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.4?¦Ìmol/L), Pseudomonas aeruginosa ATCC 27853 (MIC=50?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=1.6?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=1.6?¦Ìmol/L)"	"[Ref.31212183] 20% hemolysis at 3.1 ¦Ìmol/L, 70% hemolysis at 25 ¦Ìmol/L, 100% hemolysis at 100 ¦Ìmol/L for human red blood cells"	Linear	Free	Amidation	None	L	[Ref.31212183] No cytotoxicity information found	Not found	31212183	Bioorg Chem.?2019 Jun 8;90:103038. doi: 10.1016/j.bioorg.2019.103038.	"Pedron CN,?Ara¨²jo I,?da Silva Junior PI,?Dias da Silva F,?Torres MT,?Oliveira Junior VX"	Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
DRAMP21344	FLGALWNVFKSVF	13	[Phe]9-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	32% ¦Á-helix in 60% TFE/Water. ## 1%¦Á-helix in water.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans and Candida tropicalis IOC 4566.	"[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.2?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=0.8?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=1.6?¦Ìmol/L), Bacillus subtilis ATCC 6633 (MIC=0.8?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=1.6?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.2?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=6.3?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=0.8?¦Ìmol/L)"	"[Ref.31212183] 10% hemolysis at 1.6 ¦Ìmol/L, 40% hemolysis at 3.1 ¦Ìmol/L, 60% hemolysis at 6.3 ¦Ìmol/L, 85% hemolysis at 25 ¦Ìmol/L for human red blood cells"	Linear	Free	Amidation	None	L	[Ref.31212183] No cytotoxicity information found	Not found	31212183	Bioorg Chem.?2019 Jun 8;90:103038. doi: 10.1016/j.bioorg.2019.103038.	"Pedron CN,?Ara¨²jo I,?da Silva Junior PI,?Dias da Silva F,?Torres MT,?Oliveira Junior VX"	Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
DRAMP21345	FLGALWNVAKSLF	13	[Leu]12-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	23% ¦Á-helix in 60% TFE/Water. ## 2%¦Á-helix in water.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans and Candida tropicalis IOC 4567.	"[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.4?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=0.8?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=1.6¦Ìmol/L), Bacillus subtilis ATCC 6633 (MIC=0.8?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=0.8?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.4?¦Ìmol/L), Enterobacter cloacae ¦Â-12 (MIC=6.3?¦Ìmol/L), Pseudomonas aeruginosa ATCC 27853 (MIC=50?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=3.1?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=1.6?¦Ìmol/L)"	"[Ref.31212183] 20% hemolysis at 6.3 ¦Ìmol/L, 60% hemolysis at 12.5 ¦Ìmol/L, 75% hemolysis at 25 ¦Ìmol/L, 90% hemolysis at 50 ¦Ìmol/L for human red blood cells"	Linear	Free	Amidation	None	L	[Ref.31212183] No cytotoxicity information found	Not found	31212183	Bioorg Chem.?2019 Jun 8;90:103038. doi: 10.1016/j.bioorg.2019.103038.	"Pedron CN,?Ara¨²jo I,?da Silva Junior PI,?Dias da Silva F,?Torres MT,?Oliveira Junior VX"	Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
DRAMP21346	FLGALWNVAKSYF	13	[Tyr]12-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	24% ¦Á-helix in 60% TFE/Water. ## 2%¦Á-helix in water.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans and Candida tropicalis IOC 4568.	"[Ref.31212183] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.8?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=1.6?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=1.6?¦Ìmol/L), Bacillus subtilis ATCC 6633 (MIC=1.6?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=6.3?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.2?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=12.5?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=6.3?¦Ìmol/L)"	"[Ref.31212183] 25% hemolysis at 12.5 ¦Ìmol/L, 60% hemolysis at 25 ¦Ìmol/L, 85% hemolysis at 50 ¦Ìmol/L, 100% hemolysis at 100 ¦Ìmol/L for human red blood cells"	Linear	Free	Amidation	None	L	[Ref.31212183] No cytotoxicity information found	Not found	31212183	Bioorg Chem.?2019 Jun 8;90:103038. doi: 10.1016/j.bioorg.2019.103038.	"Pedron CN,?Ara¨²jo I,?da Silva Junior PI,?Dias da Silva F,?Torres MT,?Oliveira Junior VX"	Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
DRAMP21366	KLGALWNVAKSVF	13	[Lys]1-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"3% Helical content in water, 2% helical content in PBS (pH7.4), 30% helical content in SDS (20 mmol/L), 32% helical content in TFE/Water (3:2, v:v), 4"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans MDM8 and Candida tropicalis IOC 4560.	"[Ref.31181304] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.4?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=25?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=3.1?¦Ìmol/L);##Gram-negative bacteria: Serratia marcescens ATCC 4112 (MIC=1.6?¦Ìmol/L), Enterobacter cloacae ¦Â-12 (MIC=25?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=3.1?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=0.8?¦Ìmol/L)"	"[Ref.31181304] 15% hemolysis at 25 ¦Ìmol/L, 25% hemolysis at 50 ¦Ìmol/L, 40% hemolysis at 100 ¦Ìmol/L against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.31181304] The cell viability of MCF-7 cells induced by [Lys1]-VmCT1-NH2 is 120%, 120%, 120%, 110%, 120%, 120%, 115% and 115% at peptide concentrations of 0.8, 1.6, 3.1, 12.5, 25, 50 and 100 ¦ÌM. "	Not found	31181304	Eur J Pharm Sci.?2019 Jun 7;136:104952. doi: 10.1016/j.ejps.2019.06.006.	"Pedron CN,?de Oliveira CS,?da Silva AF,?Andrade GP,?da Silva Pinhal MA,?Cerchiaro G,?da Silva Junior PI,?da Silva FD,?Torres MT,?Oliveira VX"	The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1
DRAMP21367	FLGALWNVKKSVF	13	[Lys]9-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Antifungal"	Synthetic form	"2% Helical content in water, 3% helical content in PBS (pH7.4), 21% helical content in SDS (20 mmol/L), 21% helical content in TFE/Water (3:2, v:v), 3"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria. Antifungal activity against Candida albicans MDM8.	[Ref.31181304] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.4?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=50?¦Ìmol/L)	[Ref.31181304] 0% hemolysis at 100 ¦Ìmol/L against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.31181304] The cell viability of MCF-7 cells induced by [Lys9]-VmCT1-NH2 is 120%, 120%, 105%, 110%, 110%, 108%, 120% and 120% at peptide concentrations of 0.8, 1.6, 3.1, 12.5, 25, 50 and 100 ¦ÌM. "	Not found	31181304	Eur J Pharm Sci.?2019 Jun 7;136:104952. doi: 10.1016/j.ejps.2019.06.006.	"Pedron CN,?de Oliveira CS,?da Silva AF,?Andrade GP,?da Silva Pinhal MA,?Cerchiaro G,?da Silva Junior PI,?da Silva FD,?Torres MT,?Oliveira VX"	The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1
DRAMP21368	KLGALWNVAKSKF	13	[Lys]1[Lys]12-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"2% Helical content in water, 0% helical content in PBS (pH7.4), 19% helical content in SDS (20 mmol/L), 13% helical content in TFE/Water (3:2, v:v), 0"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans MDM8 and Candida tropicalis IOC 4560.	"[Ref.31181304] Gram-positive bacteria: Micrococcus luteus A270 (MIC=12.5?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=6.3?¦Ìmol/L);##Gram-negative bacteria: Enterobacter cloacae ¦Â-12 (MIC=25¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=6.3?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=3.1?¦Ìmol/L)"	[Ref.31181304] 0% hemolysis at 100 ¦Ìmol/L against human red blood cells	Linear	Free	Amidation	None	L	"[Ref.31181304] The cell viability of MCF-7 cells induced by [Lys1][Lys12]-VmCT1-NH2 is 105%, 110%, 95%, 100%, 110%, 120%, 120% and 120% at peptide concentrations of 0.8, 1.6, 3.1, 12.5, 25, 50 and 100 ¦ÌM. "	Not found	31181304	Eur J Pharm Sci.?2019 Jun 7;136:104952. doi: 10.1016/j.ejps.2019.06.006.	"Pedron CN,?de Oliveira CS,?da Silva AF,?Andrade GP,?da Silva Pinhal MA,?Cerchiaro G,?da Silva Junior PI,?da Silva FD,?Torres MT,?Oliveira VX"	The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1
DRAMP21369	FLKALWKVAKSVF	13	[Lys]3[Lys]7-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"0% Helical content in water, 5% helical content in PBS (pH7.4), 37% helical content in SDS (20 mmol/L), 52% helical content in TFE/Water (3:1, v:v), 0"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans MDM8 and Candida tropicalis IOC 4560.	"[Ref.31181304] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.4?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=0.4?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=0.4?¦Ìmol/L), Staphylococcus epidermidis ATCC 12228 (MIC=3.1?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=1.6?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.1?¦Ìmol/L), Enterobacter cloacae ¦Â-12 (MIC=3.1?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=0.8?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=0.4?¦Ìmol/L)"	"[Ref.31181304] 15% hemolysis at 3.1 ¦Ìmol/L, 45% hemolysis at 6.3 ¦Ìmol/L, 65% hemolysis at 12.5 ¦Ìmol/L, 85% hemolysis at 25 ¦Ìmol/L, 90% hemolysis at 100 ¦Ìmol/L against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.31181304] ¢ÙThe cell viability of MCF-7 cells induced by [Lys3][Lys7]-VmCT1-NH2 is 95%, 95%, 90%, 85%, 80%, 70%, 50%, 40% at peptide concentrations of 0.8, 1.6, 3.1, 12.5, 25, 50 and 100 ¦ÌM. ¢ÚThe cell viability of MCF-10A cells induced by [Lys3][Lys7]-VmCT1-NH2 is 120%, 120%, 120%,120%, 95% and 90% at peptide concentrations of 0.8, 1.6, 3.1, 6.3, 12.5 and 25 ¦ÌM."	Not found	31181304	Eur J Pharm Sci.?2019 Jun 7;136:104952. doi: 10.1016/j.ejps.2019.06.006.	"Pedron CN,?de Oliveira CS,?da Silva AF,?Andrade GP,?da Silva Pinhal MA,?Cerchiaro G,?da Silva Junior PI,?da Silva FD,?Torres MT,?Oliveira VX"	The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1
DRAMP21370	FLKALWNVAKKVF	13	[Lys]3[Lys]11-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"0% Helical content in water, 4% helical content in PBS (pH7.4), 28% helical content in SDS (20 mmol/L), 33% helical content in TFE/Water (3:2, v:v), 2"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans MDM8 and Candida tropicalis IOC 4560.	"[Ref.31181304] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.4?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=0.8?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=0.4?¦Ìmol/L), Staphylococcus epidermidis ATCC 12228 (MIC=1.6?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=1.6?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.2?¦Ìmol/L), Enterobacter cloacae ¦Â-12 (MIC=3.1?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=1.6?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=0.4?¦Ìmol/L)"	"[Ref.31181304] 40% hemolysis at 12.5 ¦Ìmol/L, 70% hemolysis at 25 ¦Ìmol/L, 80% hemolysis at 50 ¦Ìmol/L against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.31181304] ¢ÙThe cell viability of MCF-7 cells induced by [Lys3][Lys11]-VmCT1-NH2 is 95%, 100%, 80%, 80%, 55%, 45%, 20% and 20% at peptide concentrations of 0.8, 1.6, 3.1, 12.5, 25, 50 and 100 ¦ÌM. ¢ÚThe cell viability of MCF-10A cells induced by [Lys3][Lys11]-VmCT1-NH2 is 120%, 120%, 90%, 100%, 120% and 95%  at  peptide concentrations of 0.8, 1.6, 3.1, 6.3, 12.5 and 25 ¦ÌM."	Not found	31181304	Eur J Pharm Sci.?2019 Jun 7;136:104952. doi: 10.1016/j.ejps.2019.06.006.	"Pedron CN,?de Oliveira CS,?da Silva AF,?Andrade GP,?da Silva Pinhal MA,?Cerchiaro G,?da Silva Junior PI,?da Silva FD,?Torres MT,?Oliveira VX"	The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1
DRAMP21371	FLGALWKVAKKVF	13	[Lys]7[Lys]11-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"0% Helical content in water, 3% helical content in PBS (pH7.4), 27% helical content in SDS (20 mmol/L), 39% helical content in TFE/Water (3:2, v:v), 1"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans MDM8 and Candida tropicalis IOC 4560.	"[Ref.31181304] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.4?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=0.8?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=0.4?¦Ìmol/L), Staphylococcus epidermidis ATCC 12228 (MIC=6.3?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=3.1?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.2?¦Ìmol/L), Enterobacter cloacae ¦Â-12 (MIC=3.1?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=1.6?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=0.4¦Ìmol/L)"	"[Ref.31181304] 45% hemolysis at 12.5 ¦Ìmol/L, 100% hemolysis at 50 ¦Ìmol/L against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.31181304] ¢ÙThe cell viability of MCF-7 cells induced by [Lys7][Lys11]-VmCT1-NH2 is 105%, 105%, 95%, 85%, 65%, 45%, 25% and 25% at peptide concentrations of 0.8, 1.6, 3.1, 12.5, 25, 50 and 100 ¦ÌM. ¢ÚThe cell viability of MCF-10A cells induced by [Lys7][Lys11]-VmCT1-NH2 is 120%, 120%, 85%, 90%, 120% and 120%at peptide concentrations of 0.8, 1.6, 3.1, 6.3, 12.5 and 25 ¦ÌM."	Not found	31181304	Eur J Pharm Sci.?2019 Jun 7;136:104952. doi: 10.1016/j.ejps.2019.06.006.	"Pedron CN,?de Oliveira CS,?da Silva AF,?Andrade GP,?da Silva Pinhal MA,?Cerchiaro G,?da Silva Junior PI,?da Silva FD,?Torres MT,?Oliveira VX"	The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1
DRAMP21372	FLKALWKVAKKVF	13	[Lys]3[Lys]7[Lys]11-VmCT1-NH2 (Derived from VmCT1)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	"0% Helical content in water, 3% helical content in PBS (pH7.4), 25% helical content in SDS (20 mmol/L), 23% helical content in TFE/Water (3:2, v:v), 2"	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans MDM8 and Candida tropicalis IOC 4560.	"[Ref.31181304] Gram-positive bacteria: Micrococcus luteus A270 (MIC=0.4?¦Ìmol/L), Staphylococcus aureus ATCC 29213 (MIC=0.8?¦Ìmol/L), Bacillus megaterium ATCC 10778 (MIC=0.2?¦Ìmol/L), Staphylococcus epidermidis ATCC 12228 (MIC=3.1?¦Ìmol/L);##Gram-negative bacteria: Escherichia coli SBS 363 (MIC=1.6?¦Ìmol/L)£¬Serratia marcescens ATCC 4112 (MIC=0.1¦Ìmol/L), Enterobacter cloacae ¦Â-12 (MIC=3.1?¦Ìmol/L);##Fungi: Candida albicans MDM8 (MIC=0.8?¦Ìmol/L), Candida tropicalis IOC 4560 (MIC=0.4¦Ìmol/L)"	"[Ref.31181304] 40% hemolysis at 12.5 ¦Ìmol/L, 60% hemolysis at 25 ¦Ìmol/L, 80% hemolysis at 50 ¦Ìmol/L, 100% hemolysis at 100 ¦Ìmol/L against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.31181304] ¢ÙThe cell viability of MCF-7 cells induced by [Lys3][Lys7][Lys11]-VmCT1-NH2 is 90%, 90%, 90%, 60%, 50%, 30%, 20% and 20% at peptide concentrations of 0.8, 1.6, 3.1, 12.5, 25, 50 and 100 ¦ÌM. ¢ÚThe cell viability of MCF-10A cells induced by [Lys3][Lys7][Lys11]-VmCT1-NH2 is 120%, 120%, 85%, 120%, 115% and 120%at peptide concentrations of 0.8, 1.6, 3.1, 6.3, 12.5 and 25 ¦ÌM."	Not found	31181304	Eur J Pharm Sci.?2019 Jun 7;136:104952. doi: 10.1016/j.ejps.2019.06.006.	"Pedron CN,?de Oliveira CS,?da Silva AF,?Andrade GP,?da Silva Pinhal MA,?Cerchiaro G,?da Silva Junior PI,?da Silva FD,?Torres MT,?Oliveira VX"	The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1
DRAMP21390	RWKRHISEQLRRRDRLQR	18	K17 (Derived from ATG16)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Unknown	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31145591] Gram-positive bacteria: Staphylococcus aureus(MIC=45.5-91 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC>120¦ÌM), Pseudomonas aeruginosa (MIC>120¦ÌM);##Fungi: Candida albicans (MIC>120¦ÌM)"	"[Ref.31145591] 2% hemolysis at 600 ¦ÌM, 3% hemolysis at 700 ¦ÌM, 4% hemolysis at 800 ¦ÌM, 5% hemolysis at 900 ¦ÌM, 6% hemolysis at 1000 ¦ÌM, against mouse blood cells."	Linear	Free	Free	None	L	[Ref.31145591] No cytotoxicity information found	Not found	31145591	Bioconjug Chem. 2019 Jun 18. doi: 10.1021/acs.bioconjchem.9b00290.	"Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V"	"Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide."
DRAMP21391	RWKRHISEQLRRRDRLQRQAF	21	K18 (Derived from ATG16)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Unknown	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31145591] Gram-positive bacteria: Staphylococcus aureus(MIC=28.8-57.6 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=60-120¦ÌM), Pseudomonas aeruginosa (MIC=60-120¦ÌM);##Fungi: Candida albicans (MIC>120¦ÌM)"	"[Ref.31145591] 3% hemolysis at 500¦ÌM, 16% hemolysis at 600 ¦ÌM, 27% hemolysis at 700 ¦ÌM, 38% hemolysis at 800 ¦ÌM, 50% hemolysis at 900 ¦ÌM, 62% hemolysis at 1000¦ÌM against mouse blood cells."	Linear	Free	Free	None	L	[Ref.31145591] No cytotoxicity information found	Not found	31145591	Bioconjug Chem. 2019 Jun 18. doi: 10.1021/acs.bioconjchem.9b00290.	"Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V"	"Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide."
DRAMP21392	RWKRHISEQLRRRDRLQRQAJ	21	K22 (Derived from ATG16)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Unknown	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31145591] Gram-positive bacteria: Staphylococcus aureus(MIC=14.4-28.8 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=30-60¦ÌM), Pseudomonas aeruginosa (MIC=60-120¦ÌM);##Fungi: Candida albicans (MIC=60-120¦ÌM)"	"[Ref.31145591] 3% hemolysis at 500¦ÌM, 10% hemolysis at 600 ¦ÌM, 13% hemolysis at 700 ¦ÌM, 17% hemolysis at 800 ¦ÌM, 20% hemolysis at 900 ¦ÌM, 25% hemolysis at 1000¦ÌM against mouse blood cells."	Linear	Free	Free	The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue.	L	[Ref.31145591] No cytotoxicity information found	Not found	31145591	Bioconjug Chem. 2019 Jun 18. doi: 10.1021/acs.bioconjchem.9b00290.	"Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V"	"Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide."
DRAMP21393	RWKRHISEQLRRRDRLQRQAJ	21	K22.2 (Derived from ATG16)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Unknown	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31145591] Gram-positive bacteria: Staphylococcus aureus(MIC=4-8 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=17.5-35¦ÌM), Pseudomonas aeruginosa (MIC=17.5-35¦ÌM);##Fungi: Candida albicans (MIC=60-120¦ÌM)"	"[Ref.31145591] 3% hemolysis at 500¦ÌM, 5% hemolysis at 600 ¦ÌM, 10% hemolysis at 700 ¦ÌM, 15% hemolysis at 800 ¦ÌM, 17% hemolysis at 900 ¦ÌM, 20% hemolysis at 1000¦ÌM against mouse blood cells."	Linear	Free	"Amidation (2-Nal, position 21)"	The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue.	L	[Ref.31145591] No cytotoxicity information found	Not found	31145591	Bioconjug Chem. 2019 Jun 18. doi: 10.1021/acs.bioconjchem.9b00290.	"Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V"	"Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide."
DRAMP21394	RWKRHISEQLRRRDRLQRQAJ	21	K30 (Derived from ATG16)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Helix¨Cloop¨Chelix in the presence of anionic membrane lipids mimicking bacterial membranes.	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31145591] Gram-positive bacteria: Staphylococcus aureus(MIC=0.9-1.8 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=6.4-12.8¦ÌM), Pseudomonas aeruginosa (MIC=13.5-27¦ÌM);##Fungi: Candida albicans (MIC=30-60¦ÌM)"	"[Ref.31145591] 3% hemolysis at 600¦ÌM, 4% hemolysis at 700 ¦ÌM, 5% hemolysis at 800 ¦ÌM, 6% hemolysis at 900 ¦ÌM, 9% hemolysis at 1000 ¦ÌM,against mouse blood cells."	Linear	Acylation (Arg1 conjugated with 4-methylhexanoyl group)	"Amidation (2-Nal, position 21)"	The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue.	L	[Ref.31145591] No cytotoxicity information found	Not found	31145591	Bioconjug Chem. 2019 Jun 18. doi: 10.1021/acs.bioconjchem.9b00290.	"Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V"	"Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide."
DRAMP21395	RWKRHISEQLRRRDRLQRQAJ	21	K31 (Derived from ATG16)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Unknown	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31145591] Gram-positive bacteria: Staphylococcus aureus(MIC=1.8-3.2 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=3.2-6.4¦ÌM), Pseudomonas aeruginosa (MIC=3.2-6.4¦ÌM);##Fungi: Candida albicans (MIC=3.2-6.4¦ÌM)"	"[Ref.31145591] 50% hemolysis at 10¦ÌM, 70% hemolysis at 61¦ÌM, 75% hemolysis at 100 ¦ÌM, 80% hemolysis at 200 ¦ÌM, 85% hemolysis at 300 ¦ÌM, 90% hemolysis at 900 ¦ÌM, 92% hemolysis at 500¦ÌM against mouse blood cells."	Linear	Acylation (Arg1 conjugated with myristoyl group)	"Amidation (2-Nal, position 21)"	The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue.	L	[Ref.31145591] No cytotoxicity information found	Not found	31145591	Bioconjug Chem. 2019 Jun 18. doi: 10.1021/acs.bioconjchem.9b00290.	"Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V"	"Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide."
DRAMP21396	RWKRHISEQLRRRDRLQRQAJ	21	K33 (Derived from ATG16)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Unknown	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31145591] Gram-positive bacteria: Staphylococcus aureus(MIC=1.8-3.2 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=3.2-6.4¦ÌM), Pseudomonas aeruginosa (MIC=6.4-12.8¦ÌM);##Fungi: Candida albicans (MIC=1.8-3.7¦ÌM)"	"[Ref.31145591] 75% hemolysis at 10¦ÌM, 97% hemolysis at 123¦ÌM, 100% hemolysis at 500¦ÌM against mouse blood cells."	Linear	Acylation (Arg1 conjugated with palmitoyl group)	"Amidation (2-Nal, position 21)"	The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue.	L	[Ref.31145591] No cytotoxicity information found	Not found	31145591	Bioconjug Chem. 2019 Jun 18. doi: 10.1021/acs.bioconjchem.9b00290.	"Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V"	"Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide."
DRAMP21397	RWKRHISEQLRRRDRLQRQAJ	21	K36 (Derived from ATG16)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Unknown	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31145591] Gram-positive bacteria: Staphylococcus aureus(MIC=0.9-1.8 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=3.2-6.4¦ÌM), Pseudomonas aeruginosa (MIC=6.4-12.8¦ÌM);##Fungi: Candida albicans (MIC=15-30¦ÌM)"	"[Ref.31145591] 5% hemolysis at 200¦ÌM, 10% hemolysis at 300 ¦ÌM, 17% hemolysis at 400 ¦ÌM, 23% hemolysis at 500 ¦ÌM, 30% hemolysis at 600¦ÌM, 32% hemolysis at 700 ¦ÌM, 35% hemolysis at 800 ¦ÌM, 40% hemolysis at 900 ¦ÌM, 42% hemolysis at 1000¦ÌM against mouse blood cells."	Linear	Acylation (Arg1 conjugated with Fmoc group)	"Amidation (2-Nal, position 21)"	The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue.	L	[Ref.31145591] No cytotoxicity information found	Not found	31145591	Bioconjug Chem. 2019 Jun 18. doi: 10.1021/acs.bioconjchem.9b00290.	"Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V"	"Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide."
DRAMP21398	RWKRHISEQLRRRDRLQRQAJ	21	K46 (Derived from ATG16)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Unknown	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Antifungal activity against Candida albicans.	"[Ref.31145591] Gram-positive bacteria: Staphylococcus aureus(MIC=1.8-3.2 ¦ÌM);##Gram-negative bacteria: Escherichia coli (MIC=3.2-6.4¦ÌM), Pseudomonas aeruginosa (MIC=6.4-12.8¦ÌM);##Fungi: Candida albicans (MIC=30-60¦ÌM)"	"[Ref.31145591] 10% hemolysis at 200¦ÌM, 15% hemolysis at 500¦ÌM, 17% hemolysis at 600 ¦ÌM, 20% hemolysis at 700 ¦ÌM, 25% hemolysis at 800 ¦ÌM, 30% hemolysis at 900 ¦ÌM, 42% hemolysis at 1000¦ÌM against mouse blood cells."	Linear	Acylation (Arg1 conjugated with capryl group)	"Amidation (2-Nal, position 21)"	The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue.	L	[Ref.31145591] No cytotoxicity information found	Not found	31145591	Bioconjug Chem. 2019 Jun 18. doi: 10.1021/acs.bioconjchem.9b00290.	"Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V"	"Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide."
DRAMP21414	RWKIFKKIEKMGRNIRDGIVKAGPAIQVLGSAKAI	35	CecB Q53 (Derived from CecB E53)	No entry found	Not found	Not found	synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Random coil in aqueous solution and amphipathic helix upon interaction with cell membranes	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-nagetive bacteria. Antifungal activity against Candida albicans ATCC 1023.	"[Ref.31045339] Gram-positive bacteria: Staphylococcus aureus ATCC BAA-44(MIC>20¦ÌM), Staphylococcus epidermidis ATCC 700565(MIC=8¦ÌM);##Gram-negative bacteria:  Escherichia coli ATCC 25922 (MIC=0.15¦ÌM), Pseudomonas aeruginosa ATCC 27853(MIC=2.2¦ÌM), Pseudomonas aeruginosa ATCC 25668(MIC=2.2¦ÌM);##Fungi:Candida albicans ATCC 1023(MIC>20¦ÌM)"	"[Ref.31045339] 0.1% hemolysis at 20¦ÌM, 0.5% hemolysis at 30¦ÌM, 0.5% hemolysis at 200¦ÌM against human red blood cells"	Linear	Free	Amidation	None	L	"[Ref.31045339] ¢ÙThe cell viability of Hela cells induced by CecB Q53 is 102.6%, 104.0%, 99.1% and 95.6% at peptide concentrations of 10, 20, 30 and 200 ¦ÌM. ¢ÚThe cell viability of CCD cells induced by CecB Q53 is 108.4%, 111.5%, 108.8% and 88.5% at peptide concentrations of 10, 20, 30 and 200 ¦ÌM."	Not found	31045339	ACS Infect Dis. 2019 May 10. doi: 10.1021/acsinfecdis.9b00042.	"Romoli O, Mukherjee S, Mohid SA, Dutta A, Montali A, Franzolin E, Brady D, Zito F, Bergantino E, Rampazzo C, Tettamanti G, Bhunia A, Sandrelli F"	Enhanced Silkworm Cecropin B Antimicrobial Activity against Pseudomonas aeruginosa from Single Amino Acid Variation.
DRAMP21454	GILDWGKKVMDWIKDKM	17	"PLP1 (Insects, animals)"	A0A348G6I7	Belongs to the formicidae venom precursor-01 superfamily.	Not found	Odontomachus monticola (Trap-jaw ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	¦Á-helix predicted by Proteus	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-nagetive bacteria. Antifungal activity against Saccharomyces cerevisiae.	[Ref.30658410] Gram-positive bacteria:Staphylococcus aureus (MIC<3.1¦ÌM);##Gram-negative bacteria:Escherichia coli (MIC<3.1¦ÌM);##Fungi:Saccharomyces cerevisiae (MIC<50¦ÌM)	[Ref.30658410] 0% hemolysis at 50 ¦ÌM against rat blood cells	Linear	Free	Amidation	None	L	[Ref.30658410] No cytotoxicity information found.	Not found	30658410	Toxins (Basel). 2019 Jan; 11(1): 50. Published online 2019 Jan 17. doi:?10.3390/toxins11010050	"Naoki Tani, Kohei Kazuma, Yukio Ohtsuka, Yasushi Shigeri, Keiichi Masuko, Katsuhiro Konno, Hidetoshi Inagaki"	Mass Spectrometry Analysis and Biological Characterization of the Predatory Ant Odontomachus monticola Venom and Venom Sac Components
DRAMP21455	GWGSIFKTVGKMIAKAAVKAAPEAISAMASQNE	33	"PLP2 (Insects, animals)"	A0A348G5V8	Belongs to the formicidae venom precursor-01 superfamily.	Not found	Odontomachus monticola (Trap-jaw ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	¦Á-helix predicted by Proteus	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-nagetive bacteria. Antifungal activity against Saccharomyces cerevisiae.	[Ref.30658410] Gram-positive bacteria:Staphylococcus aureus (MIC<6.2¦ÌM);##Gram-negative bacteria:Escherichia coli (MIC<6.2¦ÌM);##Fungi:Saccharomyces cerevisiae (MIC<50¦ÌM)	[Ref.30658410] 10.4% hemolysis at 50 ¦ÌM against rat blood cells	Linear	Free	Free	None	L	[Ref.30658410] No cytotoxicity information found.	Not found	30658410	Toxins (Basel). 2019 Jan; 11(1): 50. Published online 2019 Jan 17. doi:?10.3390/toxins11010050	"Naoki Tani, Kohei Kazuma, Yukio Ohtsuka, Yasushi Shigeri, Keiichi Masuko, Katsuhiro Konno, Hidetoshi Inagaki"	Mass Spectrometry Analysis and Biological Characterization of the Predatory Ant Odontomachus monticola Venom and Venom Sac Components
DRAMP21456	KIKWGKIFKKGGKLIGKTALEAAANAAASEAISAMASQNE	40	"PLP3 (Insects, animals)"	A0A348G5V9	Belongs to the formicidae venom precursor-01 superfamily.	Not found	Odontomachus monticola (Trap-jaw ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	¦Á-helix predicted by Proteus	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-nagetive bacteria. Antifungal activity against Saccharomyces cerevisiae.	[Ref.30658410] Gram-positive bacteria:Staphylococcus aureus (MIC<25¦ÌM);##Gram-negative bacteria:Escherichia coli (MIC<3.1¦ÌM);##Fungi:Saccharomyces cerevisiae (MIC<50¦ÌM)	[Ref.30658410] 0% hemolysis at 50 ¦ÌM against rat blood cells	Linear	Free	Free	None	L	[Ref.30658410] No cytotoxicity information found.	Not found	30658410	Toxins (Basel). 2019 Jan; 11(1): 50. Published online 2019 Jan 17. doi:?10.3390/toxins11010050	"Naoki Tani, Kohei Kazuma, Yukio Ohtsuka, Yasushi Shigeri, Keiichi Masuko, Katsuhiro Konno, Hidetoshi Inagaki"	Mass Spectrometry Analysis and Biological Characterization of the Predatory Ant Odontomachus monticola Venom and Venom Sac Components
DRAMP21457	GVKELFGKAWGLVKKHLPKACGLLGYVKQ	29	"PLP4 (Insects, animals)"	A0A348G5W0	Belongs to the formicidae venom precursor-01 superfamily.	Not found	Odontomachus monticola (Trap-jaw ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	¦Á-helix predicted by Proteus	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-nagetive bacteria. Antifungal activity against Saccharomyces cerevisiae.	[Ref.30658410] Gram-positive bacteria:Staphylococcus aureus (MIC<3.1¦ÌM);##Gram-negative bacteria:Escherichia coli (MIC<3.1¦ÌM);##Fungi:Saccharomyces cerevisiae (MIC<3.1¦ÌM)	[Ref.30658410] 10.5% hemolysis at 50 ¦ÌM against rat blood cells	Cyclic	Free	Free	Cys21 is S-(carbamoylmethyl)-L-cysteine and there is a interchain disulfide bond between two PLP4 peptide molecules.	L	[Ref.30658410] No cytotoxicity information found.	Not found	30658410	Toxins (Basel). 2019 Jan; 11(1): 50. Published online 2019 Jan 17. doi:?10.3390/toxins11010050	"Naoki Tani, Kohei Kazuma, Yukio Ohtsuka, Yasushi Shigeri, Keiichi Masuko, Katsuhiro Konno, Hidetoshi Inagaki"	Mass Spectrometry Analysis and Biological Characterization of the Predatory Ant Odontomachus monticola Venom and Venom Sac Components
DRAMP21458	IWGALLGTLIPAITSAIQ	18	"PLP5 (Insects, animals)"	A0A348G5W1	Belongs to the formicidae venom precursor-01 superfamily.	Not found	Odontomachus monticola (Trap-jaw ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	¦Á-helix predicted by Proteus	Not found	None	Function: Antibacterial activity against Gram-nagetive bacteria. 	[Ref.30658410] Gram-positive bacteria:Staphylococcus aureus (MIC Negative);##Gram-negative bacteria:Escherichia coli (MIC<50¦ÌM);##Fungi:Saccharomyces cerevisiae (MIC Negative)	[Ref.30658410] 6.9% hemolysis at 10¦ÌM and 94.8% at 50 ¦ÌM against rat blood cells	Linear	Free	Amidation	None	L	[Ref.30658410] No cytotoxicity information found.	Not found	30658410	Toxins (Basel). 2019 Jan; 11(1): 50. Published online 2019 Jan 17. doi:?10.3390/toxins11010050	"Naoki Tani, Kohei Kazuma, Yukio Ohtsuka, Yasushi Shigeri, Keiichi Masuko, Katsuhiro Konno, Hidetoshi Inagaki"	Mass Spectrometry Analysis and Biological Characterization of the Predatory Ant Odontomachus monticola Venom and Venom Sac Components
DRAMP21459	IKGKKIMKNMGKAMKIAGKVAKAMAPIVVPLIVSAA	36	"PLP6 (Insects, animals)"	A0A348G5W2	Belongs to the formicidae venom precursor-01 superfamily.	Not found	Odontomachus monticola (Trap-jaw ant)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	¦Á-helix predicted by Proteus	Not found	None	Function: Antibacterial activity against Gram-positive bacteria and Gram-nagetive bacteria.	[Ref.30658410] Gram-positive bacteria:Staphylococcus aureus (MIC<3.1¦ÌM);##Gram-negative bacteria:Escherichia coli (MIC<3.1¦ÌM);##Fungi:Saccharomyces cerevisiae (MIC Negative)	[Ref.30658410] 0% hemolysis at 50 ¦ÌM against rat blood cells	Linear	Free	Amidation	None	L	[Ref.30658410] No cytotoxicity information found.	Not found	30658410	Toxins (Basel). 2019 Jan; 11(1): 50. Published online 2019 Jan 17. doi:?10.3390/toxins11010050	"Naoki Tani, Kohei Kazuma, Yukio Ohtsuka, Yasushi Shigeri, Keiichi Masuko, Katsuhiro Konno, Hidetoshi Inagaki"	Mass Spectrometry Analysis and Biological Characterization of the Predatory Ant Odontomachus monticola Venom and Venom Sac Components
DRAMP21577	WWVAARAARR	10	LP1	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antifungal"	Synthetic form	¢ÙRandom-coil conformation. ¢Ú1.9% ¦Á-helix and 22.1% ¦Â-strand in 20 mM potassium phosphate buffer; 0.6% ¦Á-helix and 37.2% ¦Â-strand in 20 mM potassium ph	LP1 appears to adopt a random-coli conformation. 	None	Function: Potential antifungal activity against Candida albicans.	"[Ref.28073163] Gram-positive bacteria: Bacillus megaterium ATCC 14581 (IC50 = 237 ¦ÌM, MIC > 20 ¦ÌM), Staphylococcus aureus ATCC 6538 (IC50 = 188 ¦ÌM, MIC > 20 ¦ÌM), Enterococcus faecalis ATCC 29212 (IC50 = 134 ¦ÌM, MIC > 20 ¦ÌM);##Gram-negative bacteria: Escherichia coli ATCC 700926 (IC50 = 805 ¦ÌM, MIC > 20 ¦ÌM);## Fungi: Candida albicans 002 ATCC 64385 (IC50 = 20 ¦ÌM, MIC > 20 ¦ÌM), C. albicans 004 ATCC MYA-2876 (IC50 = 20 ¦ÌM, MIC > 20 ¦ÌM)."	[Ref.28073163] HC50 = 1810 ¦ÌM against human red blood cells. Note:  HC50 is the half-maximal hemolytic concentration.	Linear 	Free	Amidation	None	L	No cytotoxicity information found in the reference	Not found	28073163	Biopolymers. 2017 May;108(3). doi: 10.1002/bip.23006.	"Zachary B Jenner, Christopher M Crittenden, Mart¨ªn Gonzalez, Jennifer S Brodbelt, Kerry A Bruns"	Hydrocarbon-stapled lipopeptides exhibit selective antimicrobial activity
DRAMP21494	GFLSILKKVLPKVJAHJK	18	MEP-N	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	¢Ù12% ¦Á-helical content in water.¢Ú43% ¦Á-helical content in 50% TFE. ¢Û48% ¦Á-helical content in 8mM SDS.	No other descriptive information about the structure found in the literature	None	Function: Antibacterial activity against Gram-positive and Gram-negative bacteria and Antifungal activity against Candida albicans.	"[Ref.22526241] Gram-positive bacteria: Micrococcus luteus (MIC = 1 ¦ÌM), Bacillus subtilis (MIC = 0.5 ¦ÌM), Staphylococcus aureus (MIC = 2.5 ¦ÌM);##Gram-negative bacteria: E.coli (MIC = 0.9 ¦ÌM), Pseudomonas aeruginosa (MIC = 17.3 ¦ÌM);##Fungi: Candida albicans (MIC = 15 ¦ÌM)."	[Ref.22526241] LC50 = 50 ¦ÌM. Note: LC50 is the concentration of a peptide able to lyse 50% of human erthrocytes in the assay.	Linear 	Free	Amidation	The J (position: 14 and 17) in sequence are norleucine. 	L	No cytotoxicity information found in the reference	Not found	22526241	Amino Acids. 2012 Nov;43(5):2047-58. doi: 10.1007/s00726-012-1283-1. Epub 2012 Apr 27.	"Hubert Chapuis, Ji?ina Slaninov¨¢, Lucie Bedn¨¢rov¨¢, Lenka Monincov¨¢, Milo? Bud¨§?¨ªnsk?, V¨¢clav ?e?ovsk?"	Effect of hydrocarbon stapling on the properties of ¦Á-helical antimicrobial peptides isolated from the venom of hymenoptera
DRAMP29051	KKRLKKIFKKPMVIGVTIPF	20	Ctn[15-34] (C-terminal fragment of crotalicidin)	U5KJM4	Belongs to the?cathelicidin family.	N/A	Crotalus durissus terrificus (South American rattlesnake)	"Antimicrobial, Antifungal"	Protein level	¦Á-helical	 preserves helicity	None	"Comment: Ctn[15-34] showed to be an effective antifungal peptide, displaying antibiofilm activity and, importantly, interacting with and disrupting fungal plasma membrane. Function: Potent antimicrobial peptide against Gram-negative (P.aeruginosa, K.pneumoniae, E.coli, A.baumannii) (PubMed:25100358, PubMed:26465972). Shows moderate activities against Gram-positive bacteria (E.faecalis, S.aureus, S.pyogenes) (PubMed:25100358, PubMed:26465972). Also shows antifungal activity against standard and clinical isolates of yeasts (MIC=10-40 ?M) and dermatophytes (MIC=1-5 ?M) (PubMed:27876749). Adopts an amphipathic alpha helical conformation, that may allow to partition into the target membrane (PubMed:26465972). Shows high toxicity towards human fibroblasts (micromolar ranges) (PubMed:26465972). Shows low hemolytic activities on human erythrocytes (PubMed:25100358, PubMed:26465972). Also shows toxicity (micromolar ranges) when tested on many leukemia cell lines (PubMed:26465972). In addition, when tested in vitro on the parasite Trypanosoma cruzi (responsible of the Chagas disease), is able to reduce the number of the three forms (epimastigote, trypomastigote and amastigote) by inducing cell death through necrosis (PubMed:29208061)."	"[Ref.33172206] Fungi: Candida albicans ATCC 90028 (MIC = 10 ?M or 23.7 ?g/mL), Candida albicans LABMIC 0125 (MIC = 10 ?M or 23.7 ?g/mL)"	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Free	None	L	Not found	Fungal plasma membrane	33172206	Int J Mol Sci. 2020 Nov 6;21(21):8339. doi: 10.3390/ijms21218339.	"Aguiar FLL, Santos NC, de Paula Cavalcante CS, Andreu D, Baptista GR, Gon?alves S. "	Antibiofilm Activity on Candida albicans and Mechanism of Action on Biomembrane Models of the Antimicrobial Peptide Ctn[15-34] 
DRAMP29053	AKLIPTIAL	9	RcAlb-PepI (designed in silico using as template the amino acid sequence of Rc-2S-Alb)	No entry found	Not found	N/A	Synthetic construct (Rc-2S-Alb comes from Ricinus communis (Castor bean))	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Partially ordered (non-regular) and ¦Á-helical	RcAlb-PepI and RcAlb-PepII in aqueous solution showed SRCD spectra typical of peptides that present major unordered content of secondary structure. The small (albeit significant) shift of the minimum for the RcAlb-PepII spectrum showed a more partially ordered peptide (although non-canonical) compared with RcAlb-PepI. The SRCD spectra of RcAlb-PepI and RcAlb-PepII in the film were characteristics of partially ordered (non-regular) and ¦Á-helix secondary structures.	None	Comment: RcAlb-PepI is safe and apparently effective for its intended use and has great potential for the future development of an antimicrobial agent with the ability to kill or inhibit K. pneumoniae and C. parapsilosis cells.	"[Ref.31678367] Gram-negative bacteria: E. coli (MIC50 = 102 ¦ÌM, MIC90 >  250 ¦ÌM, MBC > 250 ¦ÌM), K. pneumoniae(MIC50 = 121 ¦ÌM, MIC90 > 250 ¦ÌM, MBC > 250 ¦ÌM)##Gram-positive bacteria: S. aureus (MIC50 = 123 ¦ÌM, MIC90 > 250 ¦ÌM, MBC > 250 ¦ÌM)##Yeast: C. albicans (MIC50 = 62 ¦ÌM, MIC90 > 250 ¦ÌM, MFC > 250 ¦ÌM), C. parapsilosis (MIC50 = 14 ¦ÌM, MIC90 = 32 ¦ÌM, MFC = 103 ¦ÌM), C. tropicalis (MIC50 = 21 ¦ÌM, MIC90 = 38 ¦ÌM, MFC = 127 ¦ÌM)"	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Free	None	L	Not found	Not found	31678367	Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183092. doi: 10.1016/j.bbamem.2019.183092. Epub 2019 Oct 31.	"Dias LP, Souza PFN, Oliveira JTA, Vasconcelos IM, Ara¨²jo NMS, Tilburg MFV, Guedes MIF, Carneiro RF, Lopes JLS, Sousa DOB"	"RcAlb-PepII, a synthetic small peptide bioinspired in the 2S albumin from the seed cake of Ricinus communis, is a potent antimicrobial agent against Klebsiella pneumoniae and Candida parapsilosis "
DRAMP29054	SLRGCC	6	RcAlb-PepII (designed in silico using as template the amino acid sequence of Rc-2S-Alb)	No entry found	Not found	N/A	Synthetic construct (Rc-2S-Alb comes from Ricinus communis (Castor bean))	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Partially ordered (non-regular) and ¦Á-helical	RcAlb-PepI and RcAlb-PepII in aqueous solution showed SRCD spectra typical of peptides that present major unordered content of secondary structure. The small (albeit significant) shift of the minimum for the RcAlb-PepII spectrum showed a more partially ordered peptide (although non-canonical) compared with RcAlb-PepI. The SRCD spectra of RcAlb-PepI and RcAlb-PepII in the film were characteristics of partially ordered (non-regular) and ¦Á-helix secondary structures.	None	Comment: RcAlb-PepII is safe and apparently effective for its intended use and has great potential for the future development of an antimicrobial agent with the ability to kill or inhibit K. pneumoniae and C. parapsilosis cells.	"[Ref.31678367] Gram-negative bacteria: E. coli (MIC50 = 31 ¦ÌM, MIC90 = 29 ¦ÌM, MBC > 250 ¦ÌM), K. pneumoniae(MIC50 = 11 ¦ÌM, MIC90 = 21 ¦ÌM, MBC = 42 ¦ÌM)##Gram-positive bacteria: S. aureus (MIC50 = 79 ¦ÌM, MIC90 > 250 ¦ÌM, MBC > 250 ¦ÌM)##Yeast: C. albicans (MIC50 = 129 ¦ÌM, MIC90 > 250 ¦ÌM, MFC > 250 ¦ÌM), C. parapsilosis (MIC50 = 9 ¦ÌM, MIC90 = 17 ¦ÌM, MFC = 25 ¦ÌM), C. tropicalis (MIC50 = 29 ¦ÌM, MIC90 = 28 ¦ÌM, MFC = 67 ¦ÌM)"	"[Ref.31678367] RcAlb-PepII was not harmful to human erythrocytes, even at a concentration 10 times higher than the MBC and MFC for K. pneumoniae and C. parapsilosis, respectively."	Linear 	Free	Free	None	L	"[Ref.31678367] At 420?¦ÌM concentration (10 and 16.8 times higher than the MBC and MFC for K. pneumoniae and C. parapsilosis, respectively) RcAlb-PepII reduced only in 21.5% the Vero cell viability"	Intracellular targets	31678367	Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183092. doi: 10.1016/j.bbamem.2019.183092. Epub 2019 Oct 31.	"Dias LP, Souza PFN, Oliveira JTA, Vasconcelos IM, Ara¨²jo NMS, Tilburg MFV, Guedes MIF, Carneiro RF, Lopes JLS, Sousa DOB"	"RcAlb-PepII, a synthetic small peptide bioinspired in the 2S albumin from the seed cake of Ricinus communis, is a potent antimicrobial agent against Klebsiella pneumoniae and Candida parapsilosis "
DRAMP29055	FFPVIGRILNGIL	13	temporin G	P79875	Belongs to the?frog skin active peptide (FSAP) family.?Temporin subfamily.	N/A	Rana temporaria (European common frog)	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antibiofilm"	Protein level	Amphipathic alpha-helical (Uniprot:P79875)	Not found	None	"Function: Amphipathic alpha-helical antimicrobial peptide with activity against Gram-positive bacteria (M.luteus), Gram-negative bacteria (E.coli), and fungi (S.cerevisiae) (PubMed:22439858). Stimulates insulin release from pancreatic beta-cells in a dose-dependent manner, without increasing intracellular calcium (PubMed:29349894). Does not protects BRIN-BD11 beta-cells against cytokine-induced apoptosis (PubMed:29349894). In vivo, intraperitoneal injection together with a glucose load into mice improves glucose tolerance with a concomitant increase in insulin secretion (PubMed:29349894)."	"[Ref.33321906] S. aureus ATCC 25923 biofilm: TG was capable of killing at least 39%, 78% and 87% at 3.12, 6.25, 12.5 and 25 ?M. ##[Ref.22439858] Summary: TG had specific bactericidal activities against E. coli ATCC2592, M. luteus or S. cerevisiae."	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Amidation	None	L	[Ref.33321906]TG was shown to be harmless against human keratinocytes at all concentrations tested with a slight cytotoxicity (~20% reduction of metabolically-active cells) at the highest active concentration	Not found	33321906##22439858	Int J Mol Sci. 2020 Dec 10;21(24):9410. doi: 10.3390/ijms21249410.##BMC Biotechnol. 2012 Mar 23;12:10. doi: 10.1186/1472-6750-12-10.	"Casciaro B, Loffredo MR, Cappiello F, Fabiano G, Torrini L, Mangoni ML##Tao Ke, Su Liang, Jin Huang, Han Mao, Jibao Chen, Caihua Dong, Junyan Huang, Shengyi Liu, Jianxiong Kang, Dongqi Liu, Xiangdong Ma"	"The Antimicrobial Peptide Temporin G: Anti-Biofilm, Anti-Persister Activities, and Potentiator Effect of Tobramycin Efficacy Against Staphylococcus aureus.##A novel PCR-based method for high throughput prokaryotic expression of antimicrobial peptide genes"
DRAMP29059	FLQRIIGALGRLF	13	temporin-GHaR	No entry found	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	¦Á-helical	Not found	None	Comment: It showed potent antimicrobial activity with strong hemolytic toxicity	"[Ref.33291521] Gram-positive bacteria: S. aureus(MIC / MBC = 1.6¦ÌM / 1.6¦ÌM), B. subtilis(MIC / MBC = 12.5¦ÌM / 25¦ÌM), S. mutans(MIC / MBC = 3.1¦ÌM / 6.2¦ÌM), MRSA(MIC / MBC = 3.1¦ÌM / 3.1¦ÌM), MRSA-1(MIC /MBC = 3.1¦ÌM / 25¦ÌM), MRSA-2(MIC / MBC = 6.2¦ÌM / 12.5¦ÌM), MRSA-3(MIC / MBC = 3.1¦ÌM /6.2¦ÌM)##Gram-negative bacteria: E. coli(MIC / MBC = 6.2¦ÌM / 6.2¦ÌM),  D31(MIC /MBC = 12.5¦ÌM / 25¦ÌM), P. aeruginosa(MIC / MBC = 6.2¦ÌM / 6.2¦ÌM), PAO1(MIC / MBC = 25¦ÌM / 50¦ÌM)##Fungi: C. albicans(MIC / MBC = 12.5¦ÌM / 50¦ÌM)"	[Ref.33291521]HL50 = 48¦ÌM against human red blood cells (hRBCs)	Linear 	Free	Free	None	L	Not found	Cell membrane	33291521	Molecules. 2020 Dec 4;25(23):5724. doi: 10.3390/molecules25235724.	"Wei H, Xie Z, Tan X, Guo R, Song Y, Xie X, Wang R, Li L, Wang M, Zhang Y"	Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis 
DRAMP29060	FLQRIRGALGRLF	13	GHaR6R (variant of temporin-GHaR)	No entry found	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	¦Á-helical	Not found	None	"Comment: GHaR6R not only exerted antimicrobial activity by destroying cell membranes of planktonic bacteria, but also exhibited anti-biofilm activity.?The low-toxicity peptides of GHaR6R is expected to become promising antimicrobial candidate to develop anti-caries agents."	"[Ref.33291521] Gram-positive bacteria: S. aureus(MIC / MBC = 3.1¦ÌM / 12.5¦ÌM), B. subtilis(MIC / MBC = 25¦ÌM / 50¦ÌM), S. mutans(MIC / MBC = 12.5¦ÌM /  12.5¦ÌM), MRSA(MIC / MBC = 6.2¦ÌM / 12.5¦ÌM), MRSA-1(MIC /MBC = 12.5¦ÌM / 25¦ÌM), MRSA-2(MIC / MBC = 12.5¦ÌM / 25¦ÌM), MRSA-3(MIC / MBC = 6.2¦ÌM / 25¦ÌM)##Gram-negative bacteria: E. coli(MIC / MBC = 12.5¦ÌM / 12.5¦ÌM),  D31(MIC /MBC = 25¦ÌM / 50¦ÌM), P. aeruginosa(MIC / MBC > 50¦ÌM / 50¦ÌM), PAO1(MIC / MBC = 3.1¦ÌM / 25¦ÌM)##Fungi: C. albicans(MIC / MBC = 50¦ÌM / 50¦ÌM)"	[Ref.33291521]HL10 = 150¦ÌM against human red blood cells (hRBCs)	Linear 	Free	Free	None	L	"[Ref.33291521]GHaR6R induced a cell viability of 98%, 95% and 83% to human oral epithelial cells at 3.1¦ÌM, 6.2¦ÌM and 12.5¦ÌM."	Cell membrane	33291521	Molecules. 2020 Dec 4;25(23):5724. doi: 10.3390/molecules25235724.	"Wei H, Xie Z, Tan X, Guo R, Song Y, Xie X, Wang R, Li L, Wang M, Zhang Y"	Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis 
DRAMP29061	FLQRIIRALGRLF	13	GHaR7R (variant of temporin-GHaR)	No entry found	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	¦Á-helical	Not found	None	"Comment: GHaR6R not only exerted antimicrobial activity by destroying cell membranes of planktonic bacteria, but also exhibited anti-biofilm activity.?However, the hemolysis and cytotoxicity to HOECs of GHaR7R is too strong to make it not suitable be a good antimicrobial candidate"	"[Ref.33291521] Gram-positive bacteria: S. aureus(MIC / MBC = 3.1¦ÌM / 3.1¦ÌM), B. subtilis(MIC / MBC > 50¦ÌM / 50¦ÌM), S. mutans(MIC / MBC = 6.2¦ÌM /  12.5¦ÌM), MRSA(MIC / MBC = 3.1¦ÌM / 6.2¦ÌM), MRSA-1(MIC /MBC = 6.2¦ÌM / 25¦ÌM), MRSA-2(MIC / MBC = 6.2¦ÌM / 50¦ÌM), MRSA-3(MIC / MBC = 6.2¦ÌM / 25¦ÌM)##Gram-negative bacteria: E. coli(MIC / MBC = 3.1¦ÌM / 12.5¦ÌM),  D31(MIC /MBC = 12.5¦ÌM / 50¦ÌM), P. aeruginosa(MIC / MBC > 50¦ÌM / 50¦ÌM), PAO1(MIC / MBC > 50¦ÌM / 50¦ÌM)##Fungi: C. albicans(MIC / MBC = 25¦ÌM / 25¦ÌM)"	[Ref.33291521]HL50 = 10¦ÌM against human red blood cells (hRBCs)	Linear 	Free	Free	None	L	"[Ref.33291521]GHaR6R induced a cell viability of 62%, 50% and 39% to human oral epithelial cells at 3.1¦ÌM, 6.2¦ÌM and 12.5¦ÌM."	Cell membrane	33291521	Molecules. 2020 Dec 4;25(23):5724. doi: 10.3390/molecules25235724.	"Wei H, Xie Z, Tan X, Guo R, Song Y, Xie X, Wang R, Li L, Wang M, Zhang Y"	Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis 
DRAMP29062	FLQRIIGRLGRLF	13	GHaR8R (variant of temporin-GHaR)	No entry found	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	¦Á-helical	Not found	None	"Comment: GHaR6R not only exerted antimicrobial activity by destroying cell membranes of planktonic bacteria, but also exhibited anti-biofilm activity.?The low-toxicity peptides of GHaR6R is expected to become promising antimicrobial candidate to develop anti-caries agents."	"[Ref.33291521] Gram-positive bacteria: S. aureus(MIC / MBC = 1.6-3.1¦ÌM / 3.1¦ÌM), B. subtilis(MIC / MBC = 12.5¦ÌM / 12.5¦ÌM), S. mutans(MIC / MBC = 6.2¦ÌM /  6.2¦ÌM), MRSA(MIC / MBC = 3.1¦ÌM / 3.1¦ÌM), MRSA-1(MIC /MBC = 6.2¦ÌM / 6.2¦ÌM), MRSA-2(MIC / MBC = 3.1¦ÌM / 12.5¦ÌM), MRSA-3(MIC / MBC = 6.2¦ÌM / 12.5¦ÌM)##Gram-negative bacteria: E. coli(MIC / MBC = 3.1¦ÌM / 3.1¦ÌM),  D31(MIC /MBC = 12.5¦ÌM / 25¦ÌM), P. aeruginosa(MIC / MBC > 50¦ÌM / 50¦ÌM), PAO1(MIC / MBC = 6.2¦ÌM / 12.5¦ÌM)##Fungi: C. albicans(MIC / MBC = 12.5¦ÌM / 12.5¦ÌM)"	[Ref.33291521]HL50 = 160¦ÌM against human red blood cells (hRBCs)	Linear 	Free	Free	None	L	"[Ref.33291521]GHaR6R induced a cell viability of 83%, 64% and 50% to human oral epithelial cells at 3.1¦ÌM, 6.2¦ÌM and 12.5¦ÌM."	Cell membrane	33291521	Molecules. 2020 Dec 4;25(23):5724. doi: 10.3390/molecules25235724.	"Wei H, Xie Z, Tan X, Guo R, Song Y, Xie X, Wang R, Li L, Wang M, Zhang Y"	Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis 
DRAMP29064	FLQRIIGAWGRLL	13	GHaR9W (variant of temporin-GHaR)	No entry found	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	¦Á-helical	Not found	None	"Comment: GHaR6R not only exerted antimicrobial activity by destroying cell membranes of planktonic bacteria, but also exhibited anti-biofilm activity.?The low-toxicity peptides of GHaR6R is expected to become promising antimicrobial candidate to develop anti-caries agents."	"[Ref.33291521] Gram-positive bacteria: S. aureus(MIC / MBC = 3.1¦ÌM / 6.2¦ÌM), B. subtilis(MIC / MBC = 12.5¦ÌM / 50¦ÌM), S. mutans(MIC / MBC = 6.2¦ÌM /  6.2¦ÌM), MRSA(MIC / MBC = 6.2¦ÌM / 12.5¦ÌM), MRSA-1(MIC / MBC = 6.2¦ÌM / 12.5¦ÌM), MRSA-2(MIC / MBC = 6.2¦ÌM / 12.5¦ÌM), MRSA-3(MIC / MBC = 6.2¦ÌM / 12.5¦ÌM)##Gram-negative bacteria: E. coli(MIC / MBC = 12.5¦ÌM / 12.5¦ÌM),  D31(MIC /MBC = 12.5¦ÌM / 50¦ÌM), P. aeruginosa(MIC / MBC > 50¦ÌM / 50¦ÌM), PAO1(MIC / MBC = 25¦ÌM / 50¦ÌM)##Fungi: C. albicans(MIC / MBC = 25¦ÌM / 25¦ÌM)"	[Ref.33291521]HL50 = 90¦ÌM against human red blood cells (hRBCs)	Linear 	Free	Free	None	L	"[Ref.33291521]GHaR6R induced a cell viability of 74%, 63% and 60% to human oral epithelial cells at 3.1¦ÌM, 6.2¦ÌM and 12.5¦ÌM."	Cell membrane	33291521	Molecules. 2020 Dec 4;25(23):5724. doi: 10.3390/molecules25235724.	"Wei H, Xie Z, Tan X, Guo R, Song Y, Xie X, Wang R, Li L, Wang M, Zhang Y"	Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis 
DRAMP29087	VRLIVKVRIWRR	12	RiLK1	No entry found	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal"	Synthetic form	Disordered structure in aqueous solution; ¦Â-sheet in the presence of SDS (3 mM)	"Without SDS: 1.2% ¦Á-helix, 47.3% ¦Â-sheet, 51.5% random; t = 0 h with SDS:  7.4% ¦Á-helix, 51.4% ¦Â-sheet, 41.3% random; t = 5 min with SDS:  4.4% ¦Á-helix, 53.4% ¦Â-sheet, 42.2% random; t = 30 min with SDS: 11% ¦Á-helix, 48.7% ¦Â-sheet, 40.3% random; t = 1 h with SDS: 9.8% ¦Á-helix, 51.1% ¦Â-sheet, 39.1% random; t = 5 h with SDS: 6.7% ¦Á-helix, 54% ¦Â-sheet, 39.3% random; t = 6 h with SDS: 8% ¦Á-helix, 52% ¦Â-sheet, 40.1% random; t = 24 h with SDS: 8.4% ¦Á-helix, 53.6% ¦Â-sheet, 38% random"	None	"Comment: RiLK1 exerted potent killing effects against the clinical isolate (MBC = 1.25 M), two-fold lower than those observed against the strain isolated from food products and those determined with the parental peptide 1018-K6 against ACSSuT strain, thus, suggesting that RiLK1 might have a high potential also in the medical field."	"[Ref.32971824] Gram-negative bacteria: E.coli (IC50 = 1.20 ¡À 0.10 ¦ÌM, MBC = 2.0 ¦ÌM), S. Typhimurium (IC50 = 1.30 ¡À 0.14	¦ÌM, MBC = 2.5 ¦ÌM);##Gram-positive bacteria: S. aureus (IC50 = 1.98 ¡À 0.25 ¦ÌM, MBC = 16.0 ¦ÌM), L. monocytogenes (IC50 = 0.46 ¡À 0.01 ¦ÌM, MBC = 2.0 ¦ÌM);##Fungi: C. albicans ATCC 14053, A. brasiliensis ATCC 9341. Susceptibility testing clearly showed that RiLK1 was very effective, being able to inhibit 100% growth of both fungi at 25 ¦ÌM concentration (MFC)."	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Amidation	None	L	"[Ref.32971824] It was observed that the cell viability was recorded as 98%, 98.7%, and 98.9% at the concentrations of RiLK1 (10, 25, 50 ¦ÌM)"	Not found	32971824	Int J Mol Sci. 2020 Sep 22;21(18):6952. doi: 10.3390/ijms21186952.	"Agrillo B, Proroga YTR, Gogliettino M, Balestrieri M, Tat¨¨ R, Nicolais L, Palmieri G"	A Safe and Multitasking Antimicrobial Decapeptide: The Road from De Novo Design to Structural and Functional Characterization 
DRAMP29088	INWLKIAKKVKGML	14	MK58911 (a peptide analog from the mastoparan class of wasps)	No entry found	Not found	N/A	Galleria mellonella	"Antimicrobial, Antifungal, Antitumor"	Synthetic form	Not found	Not found	None	"Comment: MK58911 is not toxic in two mammalian cells (lung fibroblasts and glioblastoma cells) and in the G. mellonella model and demonstrates both in vitro and in vivo antifungal efficacy. Moreover, the peptide acted on the membrane of fungal cells and induced necrosis."	"[Ref.31867293] Fungi: C. neoformans (MIC = 31.2 ¦Ìg/mL), C. gattii (MIC = 15.6 ¦Ìg/mL), P. brasiliensis (MIC = 7.8 ¦Ìg/mL), P. lutzii (MIC = 15.6 ¦Ìg/mL)"	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Amidation	None	L	"[Ref.31867293]MK58911 was not toxic in lung fibroblasts (MRC5) and glioblastoma cells (U87) at tested concentrations, and a high IC50 of >500 ¦Ìg/mL was observed in both mammalian cells."	Fungal cell membrane	31867293	Front Cell Infect Microbiol. 2019 Dec 6;9:419. doi: 10.3389/fcimb.2019.00419. eCollection 2019.	"Singulani JL, Galeane MC, Ramos MD, Gomes PC, Dos Santos CT, de Souza BM, Palma MS, Fusco Almeida AM, Mendes Giannini MJS. "	"Antifungal Activity, Toxicity, and Membranolytic Action of a Mastoparan Analog Peptide "
DRAMP29089	AFIQLSKPCISDKECSIVKNYRARCRKGYCVRRRIR	36	NCR044 (Putative Late nodulin)	A0A396GSL0	Not found	MtrunA17_Chr7g021623	Medicago truncatula (Barrel medic) (Medicago tribuloides)	"Antimicrobial, Antifungal"	Protein level	¦Á-helix and ¦Â-sheet	"NCR044 contains one short (A23 to R25, G28 to C30) antiparallel ¦Â-sheet and a whiff (S11 to E14) of an ¦Á-helix."	6U6G	"Comment: The oxidized form of the NCR044 peptide exhibits potent broad-spectrum antifungal activity in vitro against four economically important fungal pathogens tested in this study. Many factors can strongly affect the efficacy of antifungal peptides. For example, disulfide bonds can help to increase potency of the oxidized form of NCR044. For deployment of NCR044 in crop protection, one could envisage further manipulating the cationicity/hydrophobicity of the oxidized or reduced NCR044 through site-directed mutagenesis and increase its antifungal potency on the surface of plant tissues without causing phytotoxicity."	"[Ref.32571919] Fungi: Botrytis cinerea (IC50 = 1.55 ¡À 0.21 ¦ÌM, IC90 = 2.72 ¡À 0.05 ¦ÌM), Fusarium graminearum (IC50 = 1.93 ¡À 0.23 ¦ÌM, IC90 = 2.80 ¡À 0.04 ¦ÌM), F.virguliforme (IC50 = 1.68 ¡À 0.20 ¦ÌM, IC90 = 2.70 ¡À 0.08 ¦ÌM), F.oxysporum (IC50 = 0.52 ¡À 0.01 ¦ÌM, IC90 = 0.71 ¡À 0.01 ¦ÌM)"	No hemolysis information or data found in the reference(s) presented in this entry	Cyclic 	Free	Free	"There are two disulfide bond between Cys15 and Cys25, Cys9 and Cys30"	L	Not found	Multiple membrane phospholipids	32571919	Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16043-16054. doi: 10.1073/pnas.2003526117. Epub 2020 Jun 22.	"Velivelli SLS, Czymmek KJ, Li H, Shaw JB, Buchko GW, Shah DM"	Antifungal symbiotic peptide NCR044 exhibits unique structure and multifaceted mechanisms of action that confer plant protection 
DRAMP29090	GIWKFLKKAKKFWK	14	MSI-1	No entry found	Not found	N/A	Synthetic construct	"Antimicrobial, Antifungal, Anti-cryptococcal"	Synthetic form	¦Á-helical in hydrophobic environment	" Furthermore, the amphipathic structure of this peptide makes it adopt an alpha helical in hydrophobic environment which may lead to the insertion of MSI-1 into the lipid bilayer of the fungal membrane to exert antifungal activity."	None	Comment: The study had demonstrated the potent antifungal activity of MSI-1 against clinical isolated C. neoformans in vitro and in a murine model of cryptococcal meningoencephalitis. 	"[Ref.32504765] Fungal strains: C. neoformans ATCC4906 (MIC = 8 ¦Ìg/mL), C. neoformans 1201 (MIC = 8 ¦Ìg/mL), C. neoformans 1768 (MIC = 16 ¦Ìg/mL), C. neoformans 2011 (MIC = 8 ¦Ìg/mL), C. neoformans 1386 (MIC = 16 ¦Ìg/mL), C. neoformans 1965 (MIC = 16 ¦Ìg/mL), C. gattii ATCC34877 (MIC = 4 ¦Ìg/mL), C. albicans ATCC10231 (MIC = 32 ¦Ìg/mL), C. albicans 2713 (MIC = 32 ¦Ìg/mL), C. albicans 2144 (MIC = 64 ¦Ìg/mL), C. albicans 1902 (MIC = 64 ¦Ìg/mL), C. albicans 1869 (MIC = 32 ¦Ìg/mL), C. albicans 2105 (MIC = 128 ¦Ìg/mL )"	No hemolysis information or data found in the reference(s) presented in this entry	Linear 	Free	Amidation	None	L	Not found	Fungal cell membrane	32504765	Peptides. 2020 Aug;130:170334. doi: 10.1016/j.peptides.2020.170334. Epub 2020 Jun 3.	"Ma L, Wei S, Ye X, Xu P, Chen H, Liu Z, Zhou C"	Antifungal activity of peptide MSI-1 against Cryptococcus neoformans infection in vitro and in murine cryptococcal meningoencephalitis
DRAMP29091	GRTSKQELCTWERGSVRQADKTIAG	25	Skh-AMP1	No entry found	"Belongs to the Lamiaceae family, subfamily Nepetoideae."	N/A	Satureja khuzistanica	"Antimicrobial, Antifungal"	Natural peptide	¦Á-helical	"Evaluation of the peptide three-dimensional structure showed that, despite the unusual distribution of amino acids in the Wheel projection, Skh-AMP1 maybe forms a ¦Á-helix structure with more hydrophobic C-terminal than that of the N-terminal. "	None	"Comment: The antifungal activity of Skh-AMP1 may be related to its ability to disrupt fungal cell membrane permeabilization and induce enhanced ROS production. Therefore, Skh-AMP1 can be introduced as a novel antifungal candidate for developing new therapeutic agents."	"[Ref.31128493] Fungi: Candida albicans ATCC 10231 (MIC = 21.6 ¦ÌM, MFC = 43.2 ¦ÌM), Candida krusei DSM 70079 (MIC = 20.7 ¦ÌM, MFC = 41.4 ¦ÌM), Candida glabrata ATCC 90030 (MIC = 19.8 ¦ÌM, MFC = 39.6 ¦ÌM), Aspergillus niger ATCC 9029 (MIC = 22.5 ¦ÌM, MFC = 45  ¦ÌM), Aspergillus flavus PFCC 100 (MIC = 23.4 ¦ÌM, MFC = 58.5 ¦ÌM), Aspergillus fumigatus Af 293 (MIC = 20.7 ¦ÌM, MFC = 41.4 ¦ÌM)"	"[Ref.31128493] Using human erythrocytes, the hemolytic activity of Skh-AMP1 at concentrations from 3.6?¦ÌM to 72?¦ÌM was reported in the range of 0.19%¨C2.1%. At the MIC concentration of 25.2?¦ÌM, a very low hemolytic activity of 0.67% (SD?=?0.02) was observed. Also, this peptide at MFC concentrations (36, 54 and 72?¦ÌM) showed 0.98%, 1.45% and 2.1% hemolytic activity for human erythrocytes."	Linear 	Free	Free	None	L	"[Ref.31128493] Skh-AMP1 has about 3.6% cytotoxicity at the concentration of 25.2?¦ÌM in 48?h. Therefore, this peptide had no significant cytotoxic effect at the concentrations of 12.6 and 25.2?¦ÌM?at 6, 24, and 48?h. However, Skh-AMP1 has about 12% and 27% cytotoxicity at the concentration of 50.4 ¦ÌM and 63 ¦ÌM, respectively"	Fungal membrane	31704210##31128493	Peptides. 2020 Jan;123:170195. doi: 10.1016/j.peptides.2019.170195. Epub 2019 Nov 6.##Phytochemistry. 2019 Aug;164:136-143. doi: 10.1016/j.phytochem.2019.05.011. Epub 2019 May 23.	"Khani S, Seyedjavadi SS, Hosseini HM, Goudarzi M, Valadbeigi S, Khatami S, Ajdary S, Eslamifar A, Amani J, Imani Fooladi AA, Razzaghi-Abyaneh M##Soghra Khani, Sima Sadat Seyedjavadi, Hadi Zare-Zardini, Hamideh Mahmoodzadeh Hosseini, Mehdi Goudarzi, Shohreh Khatami, Jafar Amani, Abbas Ali Imani Fooladi, Mehdi Razzaghi-Abyaneh"	"Effects of the antifungal peptide Skh-AMP1 derived from Satureja khuzistanica on cell membrane permeability, ROS production, and cell morphology of conidia and hyphae of Aspergillus fumigatus. ##Isolation and functional characterization of an antifungal hydrophilic peptide, Skh-AMP1, derived from Satureja khuzistanica leaves"
DRAMP29092	FKRLKKLISWIKRKRQQ	17	Hn-Mc (a chimeric peptide comprised of the N-terminus of HPA3NT3 and the C-terminus of melittin)	No entry found	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Anti-inflammatory"	Synthetic construct	Random coil or ¦Á-helical structure	"Hn-Mc adopted a random coil structure in the SUVs containing a mammalian membrane and in the buffer; however, it adopted an ¦Á-helical structure in SUVs containing a fungal membrane, indicating that it was not bound to the mammalian membrane but rather adhered to or inserted in the fungal membrane.?"	None	"Comment: Hn-Mc has a high affinity for the fungal plasma membrane and induces apoptosis in fungal cells, and provide guidance for the development of new antifungal agents. Hn-Mc is an excellent model peptide with potent antibacterial activity and non-cytotoxicity."	"[Ref.32731574]Yeast: C. albicans (MIC = 16 ¦ÌM), C. krusei (MIC = 8 ¦ÌM), C. parapsilosis (MIC = 16 ¦ÌM), C. tropicalis (MIC = 4 ¦ÌM), T. beigellii (MIC = 1 ¦ÌM);##Mold: T. rubrum (MIC = 1-2 ¦ÌM), F. moniliforme(MIC = 1-2 ¦ÌM), F. solani(MIC = 1 ¦ÌM), F. oxysporum(MIC = 1-2 ¦ÌM), A. flavus(MIC = 2-4 ¦ÌM), A. fumigatus(MIC = 2-4 ¦ÌM). ##[Ref.26028561] Drug-susceptible gram-negative bacteria: E. coli (MIC = 1 ¦ÌM), P. aeruginosa (MIC = 2 ¦ÌM); ##Drug-susceptible gram-positive bacteria: S. aureus (MIC = 2 ¦ÌM), B. subtilis(MIC = 2 ¦ÌM);##Drug-resistant bacteria:  P. aeruginosa DRPA-001 (MIC = 1 ¦ÌM),  P. aeruginosa DRPA-002 (MIC = 1 ¦ÌM),  P. aeruginosa DRPA-003 (MIC = 1 ¦ÌM),  P. aeruginosa DRPA-004 (MIC = 1 ¦ÌM),  P. aeruginosa DRPA-005 (MIC = 2 ¦ÌM), S. aureus DRSA-001 (MIC = 2 ¦ÌM), S. aureus DRSA-002 (MIC = 2 ¦ÌM), S. aureus DRSA-003 (MIC = 1 ¦ÌM), S. aureus DRSA-004 (MIC = 2 ¦ÌM), S. aureus DRSA-005 (MIC = 2 ¦ÌM)."	"[Ref.26028561] HPA3NT3 and melittin revealed the hemolysis of 68.2% and 100% at 250 ¦ÌM, respectively, but Hn-Mc was 1.1% at the same concentration"	Linear 	Free	Amidation	None	L	"[Ref.26028561] The IC50 of HPA3NT3, melittin and Hn-Mc against HaCaT cells were 49.5, 2.8 and 357.5 ¦ÌM, respectively"	Mitochondria (possibily)	32731574##26028561	Antibiotics (Basel). 2020 Jul 28;9(8):454. doi: 10.3390/antibiotics9080454.##Biochem Biophys Res Commun. 2015 Jul 31;463(3):322-8. doi: 10.1016/j.bbrc.2015.05.063. Epub 2015 May 29.	"Kim JY, Park SC, Noh G, Kim H, Yoo SH, Kim IR, Lee JR, Jang MK.##Young-Min Kim, Nam-Hong Kim, Jong-Wan Lee, Jin-Sun Jang, Yung-Hoon Park, Seong-Cheol Park, Mi-Kyeong Jang"	Antifungal Effect of A Chimeric Peptide Hn-Mc against Pathogenic Fungal Strains. ##Novel chimeric peptide with enhanced cell specificity and anti-inflammatory activity.
DRAMP29097	TQQAFQKFLAAVTSALGKQYH	21	SH¦ÂAP	No entry found	Not found	Not found	Katsuwonus pelamis	"Antimicrobial, Antibacterial,Anti-Gram+,Anti-Gram-,Antifungal"	Not found	Alpha helix	Not found	None	Function:SH¦ÂAP showed broad spectrum antimicrobial activity without hemolytic activity.Antimicrobial activity of the peptide was heatstable and pH resistant but is sensitive to proteases and salt.The action mode of SH¦ÂAP is bacteriostatic process rather than bactericidal one.	[Ref.24495783]Gram-positive bacteria:B.subtilis KCTC1021(MEC=16.0 ¦Ìg/mL); B.subtilis RM125(MEC=6.5 ¦Ìg/mL); S.aureus KCTC1621(MEC=57.0 ¦Ìg/mL);S.iniae FP5229(MEC=23.0 ¦Ìg/mL);##Gram-negative bacteria:E.coli D31(MEC=15.0 ¦Ìg/mL); E.coli KCTC1116(MEC=2.6 ¦Ìg/mL); E.coli ML35p(MEC=6.2 ¦Ìg/mL); P.aeruginosa KCTC2004(MEC=19.0 ¦Ìg/mL); S.enterica KCTC2514(MEC=2.0 ¦Ìg/mL); S.sonnei KCTC2009(MEC=6.0 ¦Ìg/mL);A.hydrophila KCTC2358(MEC>125.0 ¦Ìg/mL); V.parahaemolyticus HUFP91(MEC=1.9 ¦Ìg/mL); V.parahaemolyticus KCCM41664(MEC=1.5 ¦Ìg/mL);##Yeast:C.albicans KCTC7965(MEC=12.0 ¦Ìg/mL).	[Ref.24495783]not cause hemolysis against RBCs up to 100 ¦Ìg/mL concentration.	Linear	Free	Free	None	L	[Ref.24495783]No cytotoxicity information found.	liposomes	24495783	Fish Shellfish Immunol. 2014 Mar;37(1):173-83. 	"Seo JK, Lee MJ, Jung HG, Go HJ, Kim YJ, Park NG. "	"Antimicrobial function of SH¦ÂAP, a novel hemoglobin ¦Â chain-related antimicrobial peptide, isolated from the liver of skipjack tuna, Katsuwonus pelamis."
DRAMP29101	GFKDLLKGAAKALVKAVLF	19	Ascaphin-8 [T16A]	P0CJ32	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Anti-cancer, Antifungal"	Protein level	Alpha helix	45% ¦Á-helix was determined from the circular dichroism spectra recorded in 50% trifluoroethanol-water.	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.Antifungal activity against Candida albicans.	[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=6 ?M);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=3 ?M);##Fungi:Candida albicans ATCC 900280(MIC=6 ?M).##Cancer:human hepatoma©\derived cells HepG2 (LC50=9 ?M).	[Ref.18554256]Hemolysis against human erythrocytes (LC50=22 ?M).	Linear	Free	Amidation	None	L	[Ref.18554256]Cytotoxicity:Mouse fibroblasts L929 (LC50=5 ?M).	liposomes	18554256	Chem Biol Drug Des. 2008 Jul;72(1):58-64. 	"Conlon JM, Galadari S, Raza H, Condamine E."	"Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7."
DRAMP29102	KFFKRLLKSVRRAVKKFRKKPRLIGLSTLL	30	Hc-CATH	No entry found	Not found	Not found	Hydrophis cyanocinctus	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Anti-cancer, Antifungal"	Not found	"Alpha helix,¦Â-sheet,random coil"	"The CD spectra in H2O adopts a random-coil conformation. In the membrane-mimetic environments of SDS/H2O solutions (30¨C120 mm), the secondary structure components of Hc-CATH dissolved in 60 mm SDS/H2O were calculated as 59.9% ¦Á-helix, 16% ¦Â-sheet, 0% ¦Â-turn, and 24% random coil.When dissolved in SDS/H2O solutions with serial concentrations of NaCl (at 0, 100, 200, and 400 mm), the ¦Á-helix contents decreased slightly from 59.9 to 33.8% as the NaCl concentration increased. Simultaneously, the contents of the ¦Â-turn (0 to 14.9%) and random coil (24 to 30.5%) increased slightly. "	None	"Function:The microbial killing activity of Hc-CATH is executed through the disruption of cell membrane and lysis of bacterial cells. Antimicrobial activity of Hc-CATH in the presence of a high concentration of sodium chlorideIn addition is strong. Hc-CATH exhibited potent anti-inflammatory activity by inhibiting the LPS-induced production of nitric oxide (NO) and pro-inflammatory cytokines such as TNF-¦Á, IL-1¦Â, and IL-6."	"[Ref.26013823]Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=2.34 ?g/ml); Escherichia coli ATCC 25922(400 Mm NaCl,MIC=4.69 ?g/ml); Escherichia coli 1(MIC=2.34 ?g/ml);Escherichia coli 2(MIC=2.34 ?g/ml); Escherichia coli 3(MIC=2.34 ?g/ml); Escherichia coli 4(MIC=9.38 ?g/ml); Shigella dysenteriae(MIC=0.59 ?g/ml); Klebsiella pneumoniae 1(MIC=37.50 ?g/ml); Klebsiella pneumoniae 2(MIC=4.69 ?g/ml); Klebsiella pneumoniae 3(MIC=9.38 ?g/ml); Klebsiella pneumoniae 4(MIC=9.38 ?g/ml); Klebsiella pneumoniae 5(MIC=18.75 ?g/ml); Klebsiella pneumoniae 6(MIC=37.50 ?g/ml); Klebsiella pneumoniae 7(MIC=37.50 ?g/ml); Klebsiella pneumoniae 8(MIC=75.00 ?g/ml); Serratia marcescens(MIC>200 ?g/ml); Klebsiella oxytoca(MIC=4.69 ?g/ml); Proteus vulgaris(MIC>200 ?g/ml); Proteus mirabilis(MIC=4.69 ?g/ml); Acinetobacter baumannii 1(MIC>200 ?g/ml); Acinetobacter baumannii 2(MIC>200 ?g/ml); Stenotrophomonas maltophilia(MIC>200 ?g/ml); Stenotrophomonas maltophilia 2(MIC=9.38 ?g/ml); Pseudomonas aeruginosa ATCC 27853(MIC=18.75 ?g/ml); Pseudomonas aeruginosa 1 (MIC=37.50 ?g/ml ); Pseudomonas aeruginosa(MIC>200 ?g/ml); Salmonella paratyphi A(MIC=4.69 ?g/ml);##Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=4.69 ?g/ml); Staphylococcus aureus 1(MIC>200 ?g/ml ); Staphylococcus aureus 2(MIC>200 ?g/ml ); Staphylococcus aureus 3(MIC>200 ?g/ml ); Staphylococcus aureus 4(MIC=4.69 ?g/ml); Staphylococcus aureus 5(MIC=4.69 ?g/ml); Bacillus cereus(MIC=9.38 ?g/ml); Bacillus subtilis(MIC=75.00 ?g/ml); Enterococcus faecium(MIC=37.50 ?g/ml); Nocardia asteroides(MIC=9.38 ?g/ml); Enterococcus faecalis(MIC>200 ?g/ml); Staphylococcus epidermidis(MIC>200 ?g/ml);##Fungi:Candida albicans 1(MIC=4.69 ?g/ml); Candida albicans 2(MIC=4.69 ?g/ml); Candida albicans 3(MIC=4.69 ?g/ml); Candida albicans 4(MIC=4.69 ?g/ml); Candida albicans 5(MIC=2.34 ?g/ml); Candida albicans 6(MIC=2.34 ?g/ml); Candida glabrata 1(MIC=2.34 ?g/ml); Candida glabrata(MIC>200 ?g/ml); Cryptococcus neoformans(MIC>200 ?g/ml); Arcyria cinerea(MIC=9.38 ?g/ml);##Pathogenic bacteria:Aeromonas sobria(MIC=2.34 ?g/ml); Aeromonas hydrophila(MIC=2.34 ?g/ml); Aeromonas veronii(MIC=2.34 ?g/ml); Vibrio vulnificus(MIC=4.69 ?g/ml ); Vibrio harveyi(MIC=9.38 ?g/ml); Vibrio fluvialis(MIC=4.69 ?g/ml); Vibrio alginolyticus(MIC=4.69 ?g/ml); Vibrio parahaemolyticus(MIC=9.38 ?g/ml); Vibrio splendidus(MIC=2.34 ?g/ml); Vibrio anguillarum(MIC=18.75 ?g/ml); Edwardsiella tarda(MIC=2.34 ?g/ml)."	[Ref.26013823]5.25% Hemolysis against Human erythrocytes at 200 ?g/ml(55.12 ¦ÌM).	Linear	Free	Free	None	L	[Ref.26013823]4.70% cell death at 200 ?g/ml against Human hepatocellular carcinoma HepG2; 3.63% cell death at 200 ?g/ml against Human prostate adenocarcinoma PC-3; 1.30% cell death at 200 ?g/ml against Mouse fibroblasts L929.	liposomes	26013823	J Biol Chem. 2015 Jul 3;290(27):16633-52.	"Wei L, Gao J, Zhang S, Wu S, Xie Z, Ling G, Kuang YQ, Yang Y, Yu H, Wang Y."	Identification and Characterization of the First Cathelicidin from Sea Snakes with Potent Antimicrobial and Anti-inflammatory Activity and Special Mechanism.
DRAMP29104	LNLKALLAVAKKIL	14	Mastoparan-C(MP-C)	P01516	Not found	N/A	Vespa crabro	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Anti-cancer,Antifungal"	Protein level	"Alpha helix,random coil"	"The CD spectra in water adopts a random-coil conformation,24.85% ¦Á-helix was determined in 50% TFE."	None	"Function:The peptide was tolerant in the presence of physiological salts.MP-C  lost antimicrobial activities after incubation with 20 ¦Ìg/mL trypsin or chymotrypsin,indicating moderate protease resistance."	"[Ref.29904274]Gram-positive bacteria:Staphylococcus aureus NCTC 10788(MIC=2 ?M); Staphylococcus aureus NCTC 10788(MBC=2 ?M); Staphylococcus aureus ATCC 12493(MRSA,MIC=4 ?M); Staphylococcus aureus ATCC 12493(MRSA,MBC=4 ?M); Enterococcus faecalis NCTC 12697(MIC=8 ?M); Enterococcus faecalis NCTC 12697(MBC=8 ?M);##Gram-negative bacteria:Escherichia coli NCTC 10418(MIC=4 ?M); Escherichia coli NCTC 10418(MBC=8 ?M); Pseudomonas aeruginosa ATCC 27853(MIC=8 ?M); Pseudomonas aeruginosa ATCC 27853(MBC=16 ?M);    Fungi:Candida albicans NCTC 1467(MIC=4 ?M); Candida albicans NCTC 1467(MBC=4 ?M);##Cancer:Human squamous lung carcinoma NCI-H157(IC50=13.57 ?M);Human breast adenocarcinoma MDA-MB-435S(IC50=27.70 ?M);Human prostate adenocarcinoma PC-3(IC50=6.29 ?M);Human glioblastoma U251-MG(IC50=36.65 ?M); Human breast adenocarcinoma MCF-7(IC50=25.27 ?M).##[Ref.33285267]Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=4 ?M); Bacillus subtilis ATCC 23857(MIC=4 ?M);##Gram-negative bacterial:Escherichia coli ATCC 25922(4.5 mM KCl and 0.004 mM FeCl3,MIC=4 ?M); Pseudomonas aeruginosa ATCC 9027(4.5 mM KCl,MIC=8 ?M); Klebsiella pneumoniae ATCC 700603(MIC=8 ?M); Escherichia coli ATCC 25922(NaCl/MgCl2=150mM/1mM,MIC=4 ?M); Pseudomonas aeruginosa ATCC 9027(NaCl/MgCl2=150mM/1mM,MIC=16 ?M); Pseudomonas aeruginosa ATCC 9027(0.004mM FeCl3,MIC=4 ?M);Escherichia coli(Rifampin-resistant strain,MIC=4 ?M)."	[Ref.29904274]50% hemolysis against horse erythrocytes at 40.11 ?M.##[Ref.33285267]10% hemolysis against mouse erythrocytes at 64 ?M; 60% hemolysis against mouse erythrocytes at 256 ?M.	Linear	Free	Amidation	None	L	[Ref.29904274]Cytotoxicity:Human microvascular endothelial cells HMEC-1(IC50=57.15 ?M).##[Ref.33285267]90% Killing against Human embryonic kidney HEK293T cells at 128 ?M; Human embryonic kidney HEK293T cells(IC50=16 ?M).	liposomes	33285267##29904274	Eur J Pharm Sci. 2021 Mar 1;158:105665.##Int J Biol Sci. 2018 Apr 25;14(6):599-607.	"Zhu N, Zhong C, Liu T, Zhu Y, Gou S, Bao H, Yao J, Ni J. ##Chen X, Zhang L, Wu Y, Wang L, Ma C, Xi X, Bininda-Emonds ORP, Shaw C, Chen T, Zhou M."	Newly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria.##Evaluation of the bioactivity of a mastoparan peptide from wasp venom and of its analogues designed through targeted engineering.
DRAMP29105	CLNLKALLAVAKKILC	16	c Mastoparan-C(cMP-C)	P01516	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Anti-cancer,Antifungal"	Protein level	"Alpha helix,random coil"	"76% ¦Á-helix was determined from the circular dichroism spectra recorded in 50% TFE/10mM NH4AC solution,28% of the secondary structure  retained an ¦Á-helical domain in an aqueous environment."	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.	"[Ref.29904274]Gram-positive bacteria:Staphylococcus aureus NCTC 10788(MIC=32 ?M); Staphylococcus aureus NCTC 10788(MBC=64 ?M); Staphylococcus aureus ATCC 12493(MRSA,MIC=128 ?M); Staphylococcus aureus ATCC 12493(MRSA,MBC=128 ?M); Enterococcus faecalis NCTC 12697(MIC=128 ?M); Enterococcus faecalis NCTC 12697(MBC=128 ?M);##Gram-negative bacteria:Escherichia coli NCTC 10418(MIC=32 ?M); Escherichia coli NCTC 10418(MBC=128 ?M); Pseudomonas aeruginosa ATCC 27853(MIC=32 ?M); Pseudomonas aeruginosa ATCC 27853(MBC>512 ?M);##Fungi:Candida albicans NCTC 1467(MIC=32 ?M); Candida albicans NCTC 1467(MBC=128 ?M);##Cancer:Human squamous lung carcinoma NCI-H157(IC50=7.02 ?M);Human breast adenocarcinoma MDA-MB-435S(IC50=13.87 ?M);Human prostate adenocarcinoma PC-3(IC50=13.87 ?M);Human glioblastoma U251-MG(IC50=8.56 ?M); Human breast adenocarcinoma MCF-7(IC50=13.66 ?M).       "	[Ref.29904274]50% hemolysis against horse erythrocytes at 9.19 ?M.    	Cyclic	Free	Amidation	Disulfide bond (Cys1-Cys16)	L	[Ref.29904274]Cytotoxicity:Human microvascular endothelial cells HMEC-1(IC50=39.53 ?M).  	liposomes	29904274	Int J Biol Sci. 2018 Apr 25;14(6):599-607.	"Chen X, Zhang L, Wu Y, Wang L, Ma C, Xi X, Bininda-Emonds ORP, Shaw C, Chen T, Zhou M."	Evaluation of the bioactivity of a mastoparan peptide from wasp venom and of its analogues designed through targeted engineering.
DRAMP29106	RKKRRQRRRLNLKALLAVAKKIL	23	"t Mastoparan-C(tMP-C, Tat (49-57)-Mastoparan-C)"	"P01516,Q76PP9"	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Anti-cancer,Antifungal"	Protein level	"Alpha helix,random coil"	"28% ¦Á-helix was determined from the circular dichroism spectra recorded in 50% TFE/10mM NH4AC solution,and it adopted a random coil structure in an aqueous environment."	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.	"[Ref.29904274]Gram-positive bacteria:Staphylococcus aureus NCTC 10788(MIC=4 ?M); Staphylococcus aureus NCTC 10788(MBC=4 ?M); Staphylococcus aureus ATCC 12493(MRSA,MIC=4 ?M); Staphylococcus aureus ATCC 12493(MRSA,MBC=8 ?M); Enterococcus faecalis NCTC 12697(MIC=8 ?M); Enterococcus faecalis NCTC 12697(MBC=16 ?M);##Gram-negative bacteria:Escherichia coli NCTC 10418(MIC=2 ?M); Escherichia coli NCTC 10418(MBC=2 ?M); Pseudomonas aeruginosa ATCC 27853(MIC=4 ?M); Pseudomonas aeruginosa ATCC 27853(MBC=4 ?M);##Fungi:Candida albicans NCTC 1467(MIC=2 ?M); Candida albicans NCTC 1467(MBC=2 ?M);##Cancer:Human squamous lung carcinoma NCI-H157(IC50=2.79 ?M);Human breast adenocarcinoma MDA-MB-435S(IC50=3.86 ?M);Human prostate adenocarcinoma PC-3(IC50=3.86 ?M);Human glioblastoma U251-MG(IC50=3.36 ?M); Human breast adenocarcinoma MCF-7(IC50=3.70 ?M).     "	[Ref.29904274]50% hemolysis against horse erythrocytes at 77.94 ?M.    	Linear	Free	Amidation	None	L	[Ref.29904274]Cytotoxicity:Human microvascular endothelial cells HMEC-1(IC50=9.18 ?M).  	liposomes	29904274	Int J Biol Sci. 2018 Apr 25;14(6):599-607.	"Chen X, Zhang L, Wu Y, Wang L, Ma C, Xi X, Bininda-Emonds ORP, Shaw C, Chen T, Zhou M."	Evaluation of the bioactivity of a mastoparan peptide from wasp venom and of its analogues designed through targeted engineering.
DRAMP29131	KLLGPLLKIAAKVGSNLL	18	XT-7 [G1K]	P84381	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.Antifungal activity against Candida albicans.	[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=25 ?M);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=12.5 ?M);##Fungi:Candida albicans ATCC 900280(MIC=50 ?M);##Cancer:human hepatoma©\derived cells HepG2 (LC50=230 ?M).	[Ref.18554256]Hemolysis against human erythrocytes (LC50=400 ?M).	Linear	Free	Amidation	None	L	[Ref.18554256]No cytotoxicity information found.	liposomes	18554256	Chem Biol Drug Des. 2008 Jul;72(1):58-64.	"Conlon JM, Galadari S, Raza H, Condamine E."	"Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7."
DRAMP29132	GLLGKLLKIAAKVGSNLL	18	XT-7 [P5K]	P84381	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Alpha helix	53% ¦Á-helix was determined from the circular dichroism spectra recorded in 50% trifluoroethanol-water.	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.Antifungal activity against Candida albicans.	[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=12.5 ?M);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=3 ?M);##Fungi:Candida albicans ATCC 900280(MIC=6 ?M);##Cancer:human hepatoma©\derived cells HepG2 (LC50=14 ?M).	[Ref.18554256]Hemolysis against human erythrocytes (LC50=15 ?M).	Linear	Free	Amidation	None	L	[Ref.18554256]No cytotoxicity information found.	liposomes	18554256	Chem Biol Drug Des. 2008 Jul;72(1):58-64.	"Conlon JM, Galadari S, Raza H, Condamine E."	"Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7."
DRAMP29133	GLLGPLLKIAKKVGSNLL	18	XT-7 [A11K]	P84381	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.Antifungal activity against Candida albicans.	[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=50 ?M);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=25 ?M);##Fungi:Candida albicans ATCC 900280(MIC=25 ?M);##Cancer:human hepatoma©\derived cells HepG2 (LC50=65 ?M).	[Ref.18554256]Hemolysis against human erythrocytes (LC50=350 ?M).	Linear	Free	Amidation	None	L	[Ref.18554256]No cytotoxicity information found.	liposomes	18554256	Chem Biol Drug Des. 2008 Jul;72(1):58-64.	"Conlon JM, Galadari S, Raza H, Condamine E."	"Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7."
DRAMP29134	GLLGPLLKIAAKVGKNLL	18	XT-7 [S15K]	P84381	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.Antifungal activity against Candida albicans.	[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=12.5 ?M);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=3 ?M);##Fungi:Candida albicans ATCC 900280(MIC=25 ?M);##Cancer:human hepatoma©\derived cells HepG2 (LC50=24 ?M).	[Ref.18554256]Hemolysis against human erythrocytes (LC50=110 ?M).	Linear	Free	Amidation	None	L	[Ref.18554256]No cytotoxicity information found.	liposomes	18554256	Chem Biol Drug Des. 2008 Jul;72(1):58-64.	"Conlon JM, Galadari S, Raza H, Condamine E."	"Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7."
DRAMP29135	GLLGPLLKIAAKVGKKLL	18	"XT-7 [S15K,N16K]"	P84381	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.Antifungal activity against Candida albicans.	[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=50 ?M);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=6 ?M);##Fungi:Candida albicans ATCC 900280(MIC=6 ?M);##Cancer:hepatoma©\derived cells HepG2 (LC50=10 ?M).	[Ref.18554256]Hemolysis against human erythrocytes (LC50=60 ?M).	Linear	Free	Amidation	None	L	[Ref.18554256]No cytotoxicity information found.	liposomes	18554256	Chem Biol Drug Des. 2008 Jul;72(1):58-64.	"Conlon JM, Galadari S, Raza H, Condamine E."	"Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7."
DRAMP29136	GLLGPLLKIAAKVGSKLL	18	XT-7 [N16K]	P84381	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.Antifungal activity against Candida albicans.	[Ref.23094651]Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=6.3 ?M).##[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=12.5 ?M);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=3 ?M);##Fungi:Candida albicans ATCC 900280(MIC=12.5 ?M);##Cancer: human hepatoma©\derived cells HepG2 (LC50=22 ?M).	[Ref.23094651]50% hemolysis against rat erythrocytes at 142 ?M.##[Ref.18554256]Hemolysis against human erythrocytes (LC50=80 ?M).	Linear	Free	Amidation	None	L	[Ref.18554256]No cytotoxicity information found.	liposomes	23094651##18554256	 J Chem Inf Model. 2012 Dec 21;52(12):3341-51.##Chem Biol Drug Des. 2008 Jul;72(1):58-64.	"Kamech N, Vuki?evi? D, Ladram A, Piesse C, Vasseur J, Bojovi? V, Simuni? J, Jureti? D.##Conlon JM, Galadari S, Raza H, Condamine E."	"Improving the selectivity of antimicrobial peptides from anuran skin.##Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7."
DRAMP29137	GLLGKLLKIAAKVGKKLL	18	"XT-7 [P5K,S15K,N16K]"	P84381	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.Antifungal activity against Candida albicans.	[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=25 ?M);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=3 ?M);##Fungi:Candida albicans ATCC 900280(MIC=3 ?M);##Cancer:human hepatoma©\derived cells HepG2 (LC50=5 ?M).	[Ref.18554256]Hemolysis against human erythrocytes (LC50=25 ?M).	Linear	Free	Amidation	None	L	[Ref.18554256]No cytotoxicity information found.	liposomes	18554256	Chem Biol Drug Des. 2008 Jul;72(1):58-64.	"Conlon JM, Galadari S, Raza H, Condamine E."	"Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7."
DRAMP29138	GLLKKLLKIAAKVGKKLL	18	"XT-7 [G4K,P5K,S15K,N16K]"	P84381	Not found	N/A	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Protein level	Not found	Not found	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.Antifungal activity against Candida albicans.	[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=12.5 ?M);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=6 ?M);##Fungi:Candida albicans ATCC 900280(MIC=3 ?M);##Cancer: human hepatoma©\derived cells HepG2 (LC50=6 ?M).	[Ref.18554256]Hemolysis against human erythrocytes (LC50=25 ?M).	Linear	Free	Amidation	None	L	[Ref.18554256]No cytotoxicity information found.	liposomes	18554256	Chem Biol Drug Des. 2008 Jul;72(1):58-64.	"Conlon JM, Galadari S, Raza H, Condamine E."	"Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7."
DRAMP29140	FIGALLRPALKLLA	14	Pxt©\2	No entry found	Not found	Not found	Xenopus tropicalis	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Not found	"Alpha helix,random coil"	"3.8%,4.0%,4.9% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 10 mm Tris-HCl (pH 7.2)."	None	Function:showed growth inhibitory effects on both Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive).	[Ref.25312021]Gram-negative bacteria:Escherichia coli DH5¦Á(MIC=50 ?g/ml);##Gram-positive bacteria:Staphylococcus aureus JCM 2151(MIC=9.7 ?g/ml).##[Ref.26802742]Gram-negative bacteria:Escherichia coli NBRC 14237(MIC<12.5 ?M);Pseudomonas aeruginosa NBRC 12582(MIC<50 ?M);##Gram-positive bacteria:Staphylococcus aureus NBRC 12732(MIC<12.5 ?M);Micrococcus luteus NBRC 12708(MIC<25 ?M);##Fungi:Saccharomyces cerevisiae NBRC 10217(ND);Candida albicans NBRC 1594(ND). 	[Ref.25312021]0.4% Hemolysis against Rat erythrocytes at 20 ?M.##[Ref.26802742]2% Hemolysis against Rat erythrocytes at 50 ?M.	Linear	Free	Amidation	None	L	[Ref.25312021]No cytotoxicity information found.	Not found	25312021##26802742	FEBS J. 2015 Jan;282(1):102-13.##J Biochem. 2016 Jun;159(6):619-29.	"Shigeri Y, Yasuda A, Hagihara Y, Nishi K, Watanabe K, Imura T, Inagaki H, Haramoto Y, Ito Y, Asashima M.##Shigeri Y, Horie M, Yoshida T, Hagihara Y, Imura T, Inagaki H, Haramoto Y, Ito Y, Asashima M."	Identification of novel peptides from amphibian (Xenopus?tropicalis) skin by direct tissue MALDI-MS analysis.##Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin.
DRAMP29141	GLKEVAHSAKKFAKGFISGLTGS	23	Pxt©\3	No entry found	Not found	Not found	Xenopus tropicalis	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Not found	"Alpha helix,random coil"	"0.5%,1.2%,2.0% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 10 mm Tris-HCl (pH 7.2)."	None	Function:Antibacterial activity against Gram-positive bacteria and Gram-negative bacteria.	[Ref.25312021]Gram-negative bacteria:Escherichia coli DH5¦Á(Not active up to 150 ?g/ml);##Gram-positive bacteria:Staphylococcus aureus JCM 2151(Not active up to 150 ?g/ml).##[Ref.23935531]Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=64 ?m);Pseudomonas aeruginosa ATCC 15692(MIC >256 ?M);##Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC >256 ?M);Micrococcus luteus(MIC=32 ?M);##Fungi:Saccharomyces cerevisiae(MIC=128 ?M);##Parasite:Trypanosoma brucei(LC95=8->256 ?M).   	[Ref.25312021]0.2% Hemolysis against Rat erythrocytes at 20 ?M.##[Ref.23935531] Hemolysis against Mouse erythrocytes (HC50>256 ?m).	Linear	Free	Free	None	L	[Ref.23935531]Cytotoxicity against T-lymphocytes(IC50>256 ?M).	Not found	25312021##23935531	FEBS J. 2015 Jan;282(1):102-13.##PLoS Genet. 2013;9(8):e1003662.	"Shigeri Y, Yasuda A, Hagihara Y, Nishi K, Watanabe K, Imura T, Inagaki H, Haramoto Y, Ito Y, Asashima M.##Roelants K, Fry BG, Ye L, Stijlemans B, Brys L, Kok P, Clynen E, Schoofs L, Cornelis P, Bossuyt F."	Identification of novel peptides from amphibian (Xenopus?tropicalis) skin by direct tissue MALDI-MS analysis.##Origin and functional diversification of an amphibian defense peptide arsenal.
DRAMP29147	NLLGSLLKTGLKVGSNLL	18	Pxt©\12(CPF-St7)	P84386	Not found	N/A	Xenopus tropicalis	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-,Antifungal"	Protein level	"Alpha helix,random coil"	"0%,2.5%,6.6% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 10 mm Tris-HCl (pH 7.2);68.2%,57.4%,50.5% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 50% TFE."	None	Induced a significant and dose-dependent histamine release. 	[Ref.26802742]Gram-negative bacteria:Escherichia coli NBRC 14237(MIC<12.5 ?M);Pseudomonas aeruginosa NBRC 12582(MIC<50 ?M);##Gram-positive bacteria:Staphylococcus aureus NBRC 12732(MIC<12.5 ?M);Micrococcus luteus NBRC 12708(MIC<50 ?M);##Fungi:Candida albicans NBRC 1594(ND). ##[Ref.23935531]Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=128 ?M);Pseudomonas aeruginosa ATCC 15692(MIC >256 ?M);##Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=32 ?M);Micrococcus luteus(MIC=2 ?M);##Fungi:Saccharomyces cerevisiae(MIC=64 ?M);##Parasite:Trypanosoma brucei(LC95=2-64 ?M).     	[Ref.26802742]0% Hemolysis against Rat erythrocytes at 50 ?M.##[Ref.23935531]Hemolysis against Mouse erythrocytes(IC50=256 ?M).	Linear	Free	Amidation 	None	L	[Ref.23935531]Cytotoxicity against T-lymphocytes(IC50=128 ?M). 	liposomes	26802742##23935531	J Biochem. 2016 Jun;159(6):619-29.##PLoS Genet. 2013;9(8):e1003662. 	"Shigeri Y, Horie M, Yoshida T, Hagihara Y, Imura T, Inagaki H, Haramoto Y, Ito Y, Asashima M.##Roelants K, Fry BG, Ye L, Stijlemans B, Brys L, Kok P, Clynen E, Schoofs L, Cornelis P, Bossuyt F."	Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin.##Origin and functional diversification of an amphibian defense peptide arsenal.
DRAMP29148	KLLNLLPGLLAGIF	14	Reverse Pxt©\5	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Not found	"Alpha helix,random coil"	"10.9%,17.4%,19.8% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 10 mm Tris-HCl (pH 7.2);87.1%,77.0%,70.7% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 50% TFE."	None	Induced a significant and dose-dependent histamine release. 	[Ref.26802742]Gram-negative bacteria:Escherichia coli NBRC 14237(MIC<12.5 ?M);Pseudomonas aeruginosa NBRC 12582(MIC<50 ?M);##Gram-positive bacteria:Staphylococcus aureus NBRC 12732(MIC<12.5 ?M);Micrococcus luteus NBRC 12708(MIC<25 ?M);##Fungi:Candida albicans NBRC 1594(ND). 	[Ref.26802742]5.2% Hemolysis against Rat erythrocytes at 50 ?M.	Linear	Free	Amidation 	None	L	[Ref.26802742]No cytotoxicity information found.	liposomes	26802742	J Biochem. 2016 Jun;159(6):619-29.	"Shigeri Y, Horie M, Yoshida T, Hagihara Y, Imura T, Inagaki H, Haramoto Y, Ito Y, Asashima M."	Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin.
DRAMP29149	ALLKLAPRLLAGIF	14	Reverse Pxt-2	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Not found	"Alpha helix,random coil"	"3.6%,4.7%,7.3% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 10 mm Tris-HCl (pH 7.2);28.6%,26.8%,22.8% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 50% TFE."	None	Induced a significant and dose-dependent histamine release. 	[Ref.26802742]Gram-negative bacteria:Escherichia coli NBRC 14237(MIC<12.5 ?M);Pseudomonas aeruginosa NBRC 12582(MIC<50 ?M);##Gram-positive bacteria:Staphylococcus aureus NBRC 12732(MIC<12.5 ?M);Micrococcus luteus NBRC 12708(MIC<50 ?M);##Fungi:Candida albicans NBRC 1594(ND). 	[Ref.26802742]1.5% Hemolysis against Rat erythrocytes at 50 ?M.	Linear	Free	Amidation	None	L	[Ref.26802742]No cytotoxicity information found.	liposomes	26802742	J Biochem. 2016 Jun;159(6):619-29.	"Shigeri Y, Horie M, Yoshida T, Hagihara Y, Imura T, Inagaki H, Haramoto Y, Ito Y, Asashima M."	Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin.
DRAMP29150	LLNSGVKLGTKLLSGLLN	18	Reverse Pxt-12	No entry found	Not found	Not found	Synthetic construct	"Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal"	Not found	"Alpha helix,random coil"	"0%,0%,2.0% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 10 mm Tris-HCl (pH 7.2);23.7%,21.0%,17.9% ¦Á-helix were mearsured by CD spectra at 10 ¡ãC, 25 ¡ãC and 37 ¡ãC in 50% TFE."	None	Induced a significant and dose-dependent histamine release. 	[Ref.26802742]Gram-negative bacteria:Escherichia coli NBRC 14237(ND);Pseudomonas aeruginosa NBRC 12582(ND);##Gram-positive bacteria:Staphylococcus aureus NBRC 12732(ND);Micrococcus luteus NBRC 12708(ND);##Fungi:Candida albicans NBRC 1594(ND). 	[Ref.26802742]0% Hemolysis against Rat erythrocytes at 50 ?M.	Linear	Free	Amidation	None	L	[Ref.26802742]No cytotoxicity information found.	liposomes	26802742	J Biochem. 2016 Jun;159(6):619-29.	"Shigeri Y, Horie M, Yoshida T, Hagihara Y, Imura T, Inagaki H, Haramoto Y, Ito Y, Asashima M."	Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin.