"DRAMP_ID" "Sequence" "Sequence_Length" "Name" "Swiss_Prot_Entry" "Family" "Gene" "Source" "Activity" "Protein_existence" "Structure" "Structure_Description" "PDB_ID" "Comments" "Target_Organism" "Hemolytic_activity" "Linear/Cyclic/Branched" "N-terminal_Modification" "C-terminal_Modification" "Other_Modifications" "Stereochemistry" "Cytotoxicity" "Binding_Traget" "doi" "Reference" "Author" "Title" "DRAMP37193" "HSDAVFTDNYTRLRKQMAVKKYLNSILN" "28" "VIP" "No entry found" "Not found" "Not found" "Homo sapiens (Human)" "Antimicrobial, Antibacterial, Anti-Gram+" "Not found" "Not found" "Not found" "Not found" "Comment: Successfully secreted and expressed the biologically active human antimicrobial peptide VIP using the Pichia pastoris expression system" "Gram-positive bacteria: Staphylococcus aureus 25923 (MIC=16μmol/L)##Gram-negative bacteria: Escherichia coli 25922 (MIC=8μmol/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13345/j.cjb.170506." "[J].生物工程学报,2018,34(06):1002-1011.DOI:10.13345/j.cjb.170506." "乔想金,李文新,白丽娟:Xiangjin Qiao,Wnxin Li,Lijun Bai,Wei Hu,Huai Nan" "抗菌肽VIP在毕赤酵母中的高效表达及鉴定; Expression and identification of an antimicrobial peptide VlP in Pichiapastoris" "DRAMP37194" "GRLLRLLLRLLRG" "13" "GL(Designed with GRX2RX3RX2RG as template)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix(In cell membrane simulation environment)" "Not found" "Not found" "Comment: GF, GI, GA and GL all maintained α-helical structure in the cell membrane simulation environment, but showed random coiled morphology in PBS. GV was randomly curled in PBS and SDS, but showed a distinct α-helix structure in TFE. GW did not show α helix structure in the three solutions." "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=4μmol/L), Staphylococcus aureus ATCC 43300(MIC=2μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=4μmol/L), Bacillus subtilis CMCC 63501 (MIC=4μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=4μmol/L), Escherichia coli UB1005 (MIC=4μmol/L), S.Typhimurium ATCC 7731(MIC=4μmol/L), Pseudomonas aeruginosa 27853(MIC=4μmol/L), S.pullorum C7913(MIC=4μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.11843/j.issn.0366-6964.2019.04.012" "[J].畜牧兽医学报,2019,50(04):791-801." "徐欣瑶,董娜,李欣然:XU Xinyao,DONG Na,Ll Xinran,YANG Yang,WANG Zhihua,SHAN Anshan" "不同疏水性氨基酸对α-螺旋抗菌肽生物学活性的影响; Effect of Different Hydrophobic Amino Acids on Biological Activity of AlphaHelix Antimicrobial Peptides" "DRAMP37195" "GNNRPVYIPQPRPPHPRL" "18" "Apidaecin" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13701/j.cnki.kqyxyj.2017.05.002." "[J].口腔医学研究,2017,33(05):471-474.DOI:10.13701/j.cnki.kqyxyj.2017.05.002." "施文,马瑞,周建业,陈莉娅,马媛媛,黄慧敏,张小凤,易根云,李志强:SHl Wen ,MA Rui ,ZHOU jian-ye ,CHEN Li-ya ,MA Yuan-yuan ,HUANG Hui-min ,ZHANG xiao-feng ,yl Geng-yun ,Ll Zhi-giang" "Apidaecin型抗菌肽在毕赤酵母菌中的基因工程表达; Expression and ldentification of Apidaecin in Pichia Pastoris" "DRAMP37196" "GLLKRIKTLLPINLKALAALAKKIL" "25" "GI-1(melittin Anoplin as the N-terminal and melittin Mastoparan as the C-terminal, connected through Pro)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: melittin Anoplin as the N-terminal and melittin Mastoparan as the C-terminal, connected through Pro" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19286/j.cnki.cci.2018.12.037." "[J].煤炭与化工,2018,41(12):120-122.DOI:10.19286/j.cnki.cci.2018.12.037." "刘立伟,崔福轩,韩晓岩:Liu Liwei ,Cui Fuxuan ,Han Xiaoyan" "肽链的N,C末端对抗菌肽活性的影响研究; Effects of peptide N and C terminal on the activity of antimicrobial peptide" "DRAMP37197" "RLLKGLCKSIMKKFLRTI" "18" "NK559777-18n" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus (MIC=250μg/mL)##Gram-negative bacteria: Escherichia coli 25922 (MIC=15.6μg/mL), Salmonella typhimurium (MIC=15.6μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2017.09.028." "[J].中国畜牧兽医,2017,44(09):2739-2746.DOI:10.16431/j.cnki.1671-7236.2017.09.028." "杨霞,张殿卿,宋佳玮,肖盛中,盛金良,剡根强:YANG Xia,ZHANG Dian-qing,SONG Jia-wei,XIAO Sheng-zhong,SHENG Jin-liang,YAN Gen-qiang" "合成绵羊抗菌肽NK-Lysin抗菌活性及其对雏鸡沙门氏菌攻毒的治疗效果研究; Antimicrobial Activity of Synthesized Sheep NK-Lysin Peptides and Its Treatment for Chicken Salmonella Challenge" "DRAMP37198" "FSSLFKAGAKYLLKQVGKAGAQQLACKAANNC" "32" "BR2GK(Brevinin-2GHk)" "No entry found" "Belongs to the Brevinin-2 subfamily" "Not found" "Fejervarya multistriata" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "BR2GK exhibits a random helical conformation in water.BR2GK dissolved in an SDS solution that simulates a cell membrane environment has an α-helical structure." "Not found" "Comment: BR2GK has strong in vitro antibacterial activity and no hemolysis" "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=10μmol/L), Staphylococcus aureus ATCC 25923(MIC=20μmol/L), Enterococcus faecalis ATCC 29212(MIC=20μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=40μmol/L, Escherichia coli ATCC 35218(MIC>80μmol/L), Pseudomonas aeruginosa ATCC 27853(MIC>80μmol/L), Klebsiella pneumoniae ATCC 27853(MIC>80μmol/L),acinetobacter baumannii ATCC 19606(MIC=40μmol/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.12122/j.issn.1673-4254.2021.11.09" "[J].南方医科大学学报,2021,41(11):1657-1663." "熊唯琛,柴金为,吴洁娜,田茂林,卢万成,徐学清:XIONG Weichen,CHAI Jinwei,WU Jiena,TIAN Maolin,LU Wancheng,XU Xueqing" "蛙皮肤来源抗菌肽Brevinin-2GHk的抗菌作用机制; Antibacterial mechanism of Brevinin-2GHk, an antimicrobial peptide from Fejervarya limnocharis skin" "DRAMP37199" "GFSSLFKAGAKYFLKQVGKAGAQQLACKAANNC" "33" "brevinin-2GHa1" "No entry found" "Not found" "Not found" "Hylarana guentheri" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus(MIC=3.9μg/mL), Bacillus subtilis (MIC=2.0μg/mL)##Gram-negative bacteria: Salmonella (MIC=250μg/mL), Escherichia coli (MIC=7.8μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13865/j.cnki.cjbmb.2014.11.11." "[J].中国生物化学与分子生物学报,2014,30(11):1126-1132.DOI:10.13865/j.cnki.cjbmb.2014.11.11." "俞世宏,陈涛涛,户佩,洪晶:YU Shi-Hong,CHEN Tao-Tao,HU Pei,HONG Jing" "沼水蛙抗菌肽brevinin-2GHa1分离纯化及结构分析; Purification and Structure Analysis of an Antibacterial Peptide Brevinin-2GHa1 from Skin Secretion of Hylarana guentheri" "DRAMP37200" "MWHLKLCAVLMIFLLLLGQIDGSPIPEVSSAKRRPRRMTPFWRGVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE" "77" "LEAP-2(contains signal peptide and precursor peptide)" "No entry found" "Not found" "Not found" "Homo sapiens " "Antimicrobial, Antibacterial, Anti-Gram+" "Not found" "Alpha helix、Random coil" "Alpha helix accounted for 54.55%, and 42 amino acid residues participated. The β-angle accounted for 2.6% and was involved by 2 amino acid residues. Random coil accounted for 42.9%, and 33 amino acid residues were involved" "2L1Q(only mature peptides contained)" "Comment: LEAP-2 not only has antibacterial activity, it is also a novel regulator of food intake and weight. LEAP-2, as an endogenous antagonist of ghrelin receptor, can inhibit ghrelin in the body and induce food intake, providing a new way for the development of novel anti-obesity drugs and weight maintenance after weight loss." "Gram-positive bacteria: Bacillus megaterium" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13417/j.gab.041.000407." "[J].基因组学与应用生物学,2022,41(02):407-414.DOI:10.13417/j.gab.041.000407." "王珊珊,高琪,任艳艳,路宏朝,王令,张涛:Wang Shanshan,Gao Qi,Ren Yanyan,Lu Hongzhao,Wang Ling,Zhang Tao" "人Ⅱ型肝脏表达抗菌肽LEAP-2的生物信息学分析; Bioinformatics Analysis of Human Liver-expressed Antimicrobial Peptide 2" "DRAMP37201" "GILKKFMLHRGTKVYKMRTLSKRSH" "25" "Scolopin-2-NH2 (S-2-N)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Scolopin-2-NH2 (S-2-N), obtained through amidation modification of Scolopin 2, has stronger antibacterial activity than its parent peptide Scolopin-2 (S-2)." "Gram-positive bacteria: Staphylococcus aureus (MIC=15μmol/L), Bacillus subtilis(MIC=21μmol/L)##Gram-negative bacteria: Escherichia coli(K2Ds1) (MIC=10μmol/L), Salmonella (MIC=15μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane, DNA" "10.13560/j.cnki.biotech.bull.1985.2018-0476." "[J].生物技术通报,2018,34(11):179-190.DOI:10.13560/j.cnki.biotech.bull.1985.2018-0476." "卢佳,邓秋萍,任文华:LU Jia,DENG Qiu-ping,REN Wen-hua" "少棘蜈蚣抗菌肽Scolopin 2-NH2的抗菌作用机制研究; Mechanism of Antimicrobial Peptide Scolopin 2-NH2 Isolated from Scolopendra subspinipes mutilans" "DRAMP37202" "GRAARAAARAARG" "13" "GA(Designed with GRX2RX3RX2RG as template)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix(In cell membrane simulation environment)" "Not found" "Not found" "Comment: GF, GI, GA and GL all maintained α-helical structure in the cell membrane simulation environment, but showed random coiled morphology in PBS. GV was randomly curled in PBS and SDS, but showed a distinct α-helix structure in TFE. GW did not show α helix structure in the three solutions." "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC>128μmol/L), Staphylococcus aureus ATCC 43300(MIC>128μmol/L), Staphylococcus epidermidis ATCC 12228(MIC>128μmol/L), Bacillus subtilis CMCC 63501 (MIC=16μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC>128μmol/L), Escherichia coli UB1005 (MIC>128μmol/L), S.Typhimurium ATCC 7731(MIC>128μmol/L), Pseudomonas aeruginosa 27853(MIC>128μmol/L), S.pullorum C7913(MIC>128μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.11843/j.issn.03666964.2019.04.012" "[J].畜牧兽医学报,2019,50(04):791-801." "徐欣瑶,董娜,李欣然,杨洋,王志华,单安山: XU Xinyao,DONG Na,LI Xinran,YANG Yang,WANG Zhihua,SHAN Anshan" "不同疏水性氨基酸对α-螺旋抗菌肽生物学活性的影响; Effect of Different Hydrophobic Amino Acids on Biological Activity of Alpha Helix Antimicrobial Peptides" "DRAMP37203" "FLRRLWGVAKRLF" "13" "LP-M3(Derived from Lausporin-1)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Cationic α-helical antimicrobial peptide composed of 16 amino acid residues" "Not found" "Comment: Based on the Lausporin-1 sequence and using basic amino acid substitution method, four derivative peptides LP-M1, LP-M2, LP-M3 and LP-M4 were designed. Compared with the wild type, these peptides have better effects on the studied "ESKAPE" All pathogenic bacteria showed good antibacterial activity (MIC: 5-20 μg/mL), and the hemolytic activity of LP-M3 was significantly reduced." "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=5μmol/L), Staphylococcus aureus ATCC 25923(MIC=5μmol/L), Enterococcus faecalis ATCC 29212(MIC=10μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=10μmol/L, Escherichia coli ATCC 35218(MIC=10μmol/L), Pseudomonas aeruginosa ATCC 27853(MIC=10μmol/L), Klebsiella pneumoniae ATCC 27853(MIC=5μmol/L),acinetobacter baumannii ATCC 19606(MIC=5μmol/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13819/j.issn.2096-708X.2021.05.001" "[J].湖北医药学院学报,2021,40(05):441-445+453.DOI:10.13819/j.issn.2096-708X.2021.05.001." " 罗旭东,张凯月,蒋僡雯,黎方琰,陈宗运: LUO Xu-dong,ZHANG Kai-yue,JIANG Hui-wen,LI Fang-yan,CHEN Zong-yun" "基于蝎抗菌肽Lausporin-1设计衍生肽以优化其抗“ESKAPE”病原菌活性; Analogues Designed from Scorpion-Derived Peptide Lausporin-1Exhibit Improved Antimicrobial Activity Against ‘ESKAPE’ Pathogens" "DRAMP37204" "MKKTAIAIAVALAGFARRKKK" "21" "P-KKK" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 26003##Gram-negative bacteria: Escherichia coli 44113." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16121/j.cnki.cn45-1347/r.2017.02.03" "[J].内科,2017,12(02):153-156.DOI:10.16121/j.cnki.cn45-1347/r.2017.02.03." " 谭咪乐,李永杰,黄凌凌,梁宁生:TAN Mile,LI Yongjie,HUANG Lingling,LIANG Ningsheng" "将大肠杆菌OmpA信号肽改造成为抗菌肽的研究; Study on conversion of Omp A signal peptide of Escherichia coli to antimicrobial peptide" "DRAMP37205" "VQ" "2" "PG-YGT-M1(2)" "No entry found" "Not found" "Not found" "Taraxacum mongolicum" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: This research is helpful for the development and utilization of Taraxacum mongolicum protein peptides and the production of new Taraxacum mongolicum antimicrobial peptides." "Gram-positive bacteria: Staphylococcus aureus##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16519/j.cnki.1004-311x.2019.04.0056" "[J].生物技术,2019,29(04):330-335.DOI:10.16519/j.cnki.1004-311x.2019.04.0056." "彭建,赵行行,吴兆颖,王涛,尚小丽,国果: PENG Jian,ZHAO Xing-xing,WU Zhao-ying,WANG Tao,SHANG Xiao-li,GUO Guo" "抗菌肽Cec4的结构改造及抗菌活性研究; Structural modification and antibacterial related activity study of antimicrobial peptide Cec4" "DRAMP37206" "FKCRRWQWRWKKLGARLKVLTTG" "23" "Lfcin15-Me8" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Alpha helix" "Contains 12 α-helices, α-helices account for 65.22% of the secondary structure" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Pseudomonas aeruginosa." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.3969/j.issn.1005-7021.2016.05.011" "[J].微生物学杂志,2016,36(05):62-67." "赵春雨,赵晓宇,李响,袁海峰,郑艳贺:ZHAO Chun-yu,ZHAO Xiao-yu,LI Xiang,YUAN Hai-feng,ZHENG Yan-he" "抗菌肽Lfcin15-Me8分子设计及对老年呼吸道致病菌铜绿假单胞菌的抑菌性能分析; Molecular Design of Antimicrobial Peptide Lfcin15-Me8 and Its Inhibition Performance Analysis on Respiratory Tract Pathogenic Pseudomonas aeruginosa in Senile" "DRAMP37207" "KKIKKLIKSAKIWLKIIA" "18" "MAF-1A18S5(Derived from MAF-1A)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: The derived peptide MAF-1A22S6 has obvious antifungal effect in vitro" "Fungus:Candida albican ATCC10231 (MIC=31.25 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19367/j.cnki.2096-8388.2023.01.004." "[J].贵州医科大学学报,2023,48(01):25-32.DOI:10.19367/j.cnki.2096-8388.2023.01.004." "黄敏慧,曾晔,张迎春,李彩多,吴建伟,陈峥宏,王涛: HUANG Minhui,ZENG Ye,ZHANG Yingchun,LI Caiduo,WU Jianwei,CHEN Zhenghong,WANG Tao" "抗菌肽MAF-1A洐生肽的设计及其抗白色念珠菌活性; Design of antibacterial peptide MAF-1A derivatives and their activity against Candida albicans" "DRAMP37208" "GBKRLVQRLKDBLRNLV" "17" "17BIPHE2" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 25293(MIC=8.000μmol/L), Staphylococcus aureus 05(MIC=8.000μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13344/j.microbiol.china.160394." "[J].微生物学通报,2017,44(04):872-880.DOI:10.13344/j.microbiol.china.160394." "回丽媛,李军,朱明星,王秀青: HUI Li-Yuan,LI Jun,ZHU Ming-Xing,WANG Xiu-Qing" "抗菌肽17BIPHE2对金黄色葡萄球菌生物被膜的抑制作用; Inhibition of Staphylococcus aureus biofilm by antimicrobial peptide 17BIPHE2" "DRAMP37209" "GLRPKYSRWL" "10" "GW10" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: The presence of basic amino acids in GW10 promotes its binding to the cell membrane, and its hydrophobic part is inserted into the hydrophobic region of the cell membrane, improving antibacterial activity by changing the membrane structure or causing the inactivation of membrane proteins." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.26914/c.cnkihy.2018.017696." "[J].光谱学与光谱分析,2018,38(S1):365-366." "吴镛峰,霍妲雨佳,祖莉莉: WU Yong-feng,HUO Dayu-jia,ZU Li-li" "电喷雾电离-飞行时间质谱研究抗菌肽GW10的气相碰撞诱导解离过程; Collision-Induced Dissociation Study of Antimicrobial peptide GW10 by ESI-TOF-MS/MS" "DRAMP37210" "KIKWFKTMKSIAKFIAKEQMKKHLGGE" "27" "Lycotoxin-2" "No entry found" "Not found" "Not found" "H.carolinensis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37211" "VLLIRKKK" "8" "SAMP1-A1(Derived from SAMP1)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "The secondary structure of SAMP1 and most similar peptides is dominated by α helix and random curling. In 51% (volume fraction) TFE solution, the proportion of alpha helix increases." "Not found" "Comment: The hydrophobic amino acid residues in SAMP1 sequence were replaced by isoleucine (Ile), valine (Val), leucine (Leu) and tryptophan (Trp), and the effect of hydrophobic change on the action of antimicrobial peptides was studied. At the same time, 8 new similar peptides were designed and synthesized by means of amino acid residue substitution and sequence rearrangement." "Gram-positive bacteria: Staphylococcus aureus (MIC>250μg/mL), Bacillus subtilis (MIC=3.9μg/mL), Listeria monocytogenes (MIC=1.9μg/mL)##Gram-negative bacteria: Candida tropicalis (MIC=1.9μg/mL), Escherichia coli (MIC=31.25μg/mL), Pseudomonas aeruginosa 27853(MIC=250μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7503/cjcu20180680" "[J].高等学校化学学报,2019,40(04):705-711." "常俊朋,赵佳瑞,陈思佳,孟凯,石微妮,李瑞芳:CHANG Junpeng,ZHAO Jiarui,CHEN Sijia,MENG Kai,SHI Weini,LI Ruifang" "抗菌肽SAMP1及其类似肽的构效关系; Structure-activity Relationship of Antimicrobial Peptide SAMP1 and Its Analog Peptides" "DRAMP37212" "GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK" "45" "hBD3(humanβdefensin3, hBD3)" "No entry found" "Not found" "Not found" "Homo sapiens " "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Pseudomonas aeruginosa PAO1(MIC=32μg/mL), Klebsiella Pneumoniae(MIC=22.3μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13241/j.cnki.pmb.2014.32.006." "[J].现代生物医学进展,2014,14(32):6225-6228.DOI:10.13241/j.cnki.pmb.2014.32.006." "宋珍,李镛,阴振晨,李擎天: SONG Zhen,LI Yong,YIN,Zhen-chen,LI Qing-tian" "抗菌肽人β防御素3对铜绿假单胞菌PAO-1株的抑制作用; The Inhibition on Pseudomonas Aeruginosa PAO-1 by Antimirobial Peptide Human β Defensin 3" "DRAMP37213" "FLRHVVKILSKYL" "13" "RGD-T-La(FS) (RGD-chimera peptide)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: Conjugate RGD to synthesize polypeptide RGD-chimera to increase the targeting effect of anti-tumor peptide on tumor cells" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "RGD" "None" "L" "No cytotoxicity information found" "Not found" "10.13200/j.cnki.cjb.002626" "[J].中国生物制品学杂志,2019,32(09):987-992.DOI:10.13200/j.cnki.cjb.002626." "张秋利,刘梦月,姜轩,金天明,赵瑞利,,马吉飞: ZHANG Qiu-li,LIU Meng-yue,JIANG Xuan,JIN Tian-ming,ZHAO Rui-li,MA Ji-fei,FU Chao,SHANG Zi-yu" "新抗菌肽RGD-嵌合体靶向抗黑色素瘤活性; Antitumor activity of a novel antibacterial peptide RGD-chimera targeting melanoma" "DRAMP37214" "RRLHPQHQRFPRERPWPKPLSLPLPRPGPRPWPKPL" "36" "Bac4(Bovine cathelicidin antimicrobial peptides)" "No entry found" "Not found" "Not found" "Fetal Bovine Serum" "Antimicrobial, Antibacterial" "Not found" "Random coil" "Not found" "Not found" "Comment: Bovine cathelicidin antimicrobial peptides can act on the cell wall or cell membrane of bacteria, thereby causing bacterial death." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.3969/j.issn.1008-7516.2019.01.008" "[J].河南科技学院学报(自然科学版),2019,47(01):37-42." "李杰,杭柏林,宁春妹,司素锦,张慧辉,胡建和:LI Jie,HANG Bolin,NING Chunmei,SI Sujin,ZHANG Huihui,HU Jianhe" "牛源cathelicidin类抗菌肽的生物信息学分析; Bioinformatic analysis of bovine cathelicidin antimicrobial peptides" "DRAMP37215" "CRNGCALKAIAKLKLKKLILLK" "22" "CRLK" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13753/j.issn.1007-6611.2017.11.013" "[J].山西医科大学学报,2017,48(11):1149-1153.DOI:10.13753/j.issn.1007-6611.2017.11.013." "侯磊,岳晨莉,何莉,贾辉,白俊: HOU Lei,YUE Chenli,HE Li,JIA Hui,BAI Jun" "连接链对包含CisoDGRC结构抗菌肽诱导乳腺癌细胞凋亡的影响; Effect of connection chain on apoptosis induced by antibacterial peptide containing CisoDGRC in breast cancer cells" "DRAMP37216" "MGQARGAVSSVAGRAQGM" "18" "C4(Peptide derived from Cn-AMP1)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: The designed and synthesized peptides C2 and C4 had good antibacterial activity against gram-negative and gram-positive bacteria, and the activity was significantly improved compared with the parent peptides Cn-AMP1." "Gram-positive bacteria: Staphylococcus aureus CICC 23656 (MIC=16 µM), Staphylococcus epidermidis CICC 10294 (MIC=64 µM), Clostridium perfringens ATCC 13124 (MIC=16 µM), Bacillus cereus CICC 23828 (MIC=32 µM), Streptococcus pyogenes CICC 10373 (MIC=32 µM), Streptococcus faecalis CICC 23658 (MIC=16 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=32 µM),Pseudomonas aeruginosa CICC 21636 (MIC=64 µM),Salmonella Enteritidis CICC 21535 (MIC=64 µM),Klebsiella pneumonia ATCC 10031 (MIC=32 µM), Shigella baumannii ATCC 9027(MIC=16 µM), Enterobacter sakazakii CICC 21544(MIC=16 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "IC50 = 445.2 μM targeting on BEAS-2B cell cultured in DMEM-H medium containing 11% fetal bovine serum. The original article did not specify a positive control." "Cell membrane" "10.13819/j.issn.2096-708X.2021.05.001" "[J].齐齐哈尔医学院学报,2023,44(23):2208-2211." "陈柯,衣同辉,王宏兰,房丹丹,刘大鹏,高涵,潘洪明,李淑艳,王洁,刘桃源:Chen Ke,Yi Tonghui,Wang Honglan,Fang Dandan,Liu Dapeng,Gao Han,Pan Hongming,Li Shuyan,Wang Jie,Liu Taoyuan" "基于短链抗菌肽Cn-AMP1的拼接肽合成及抗菌活性研究; Study on synthesis and antibacterial activity of splicing peptides based on short chain antibacterial peptide Cn-AMP1" "DRAMP37217" "VNFKLLSHSLLVTLASHL" "18" "P3" "No entry found" "Not found" "Not found" "bovine" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2017.01.008" "[J].中国畜牧兽医,2017,44(01):59-64.DOI:10.16431/j.cnki.1671-7236.2017.01.008." "李杰,杭柏林,秦爱建,钱琨,胡建和:LI Jie,HANG Bo-lin,QIN Ai-jian,QIAN Kun,HU Jian-he" "牛血红蛋白源抗菌肽P3及其类似肽的生物信息学分析; Bioinformatics Analysis of Antimicrobial Peptide P3 from Bovine Hemoglobin and Its Analogs" "DRAMP37218" "RKGWFKAMKSIAKFIAKEKLKEHL" "24" "lycosin-I" "No entry found" "Not found" "Not found" "Lycosa singorensis" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: Lycosin-I has a good antibacterial effect against Pseudomonas aeruginosa under in vitro conditions, especially MDRPA, which can show good in vitro antibacterial activity at a lower concentration of 8 μg/mL." "Gram-negative bacteria: Pseudomonas aeruginosa MDRPA (MIC=12μg/mL), Pseudomonas aeruginosa non-MDRPA (MIC=10μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13602/j.cnki.jcls.2018.04.04" "[J].临床检验杂志,2018,36(04):253-258.DOI:10.13602/j.cnki.jcls.2018.04.04." "谭丽,程优,柏乐,王玲,贺腊姑,胡敏:TAN Li,CHENG You,BAI Le,WANG Ling,HE Lagu,HU Min" "抗菌肽lycosin-I对铜绿假单胞菌临床分离株的体外抗菌活性分析; In vitro antibacterial activity analysis of antibacterial peptide lycosin-I against clinical isolates of Pseudomonas aeruginosa" "DRAMP37219" "FFGLIPGLVGSLISAFK" "17" "CeAP1" "No entry found" "Not found" "Not found" "Centruroides exilicauda" "Antimicrobial, Antibacterial, Anti-Gram+" "Not found" "Alpha helix" "Amphiphilic α-helix structure. no helix structure in aqueous environment, induced into α-helix structure in hydrophobic environment." "Not found" "Function: Be suitable for the treatment of infection caused by multi-drug-resistant bacteria and has potential medicinal value." "Gram-positive bacteria: Staphylococcus aureus AB 94004 (MIC=16.0 µM), Bacillus.megaterium AB 90008(MIC=32.0 µM)." "HD50 = 52.0 μM against on human red blood cells . 1% Triton X-100 were used as the positive control." "Linear" "Random coil" "Random coil" "None" "L" "No cytotoxicity information found" "DNA, RNA" "10.13350/j.cjpb.240202." "Journal of Pathogen Biology. 2024 Feb;19(2):130-136" "敖日格乐,胡和珠拉,胡伊力格其,曾宪春:Aorigele,Huhezhula,Huyiligeqi,ZENG Xianchun" "蝎毒素抗菌肽CeAP1的生物信息学分析与生物活性鉴定; Functional identification and bioinformatics analysis of antimicrobial peptide Ce AP1 from scorpion venom" "DRAMP37220" "MAK" "3" "MAK" "No entry found" "Not found" "Not found" "Dendrobium aphyllum" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Pseudomonas aeruginosa " "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13982/j.mfst.1673-9078.2019.6.008." "[J].现代食品科技,2019,35(06):56-63.DOI:10.13982/j.mfst.1673-9078.2019.6.008." "刘映君,李素芬,王琴,刘袆帆:LIU Ying-jun,LI Su-fen,WANG Qin,LIU Hui-fan" "抗菌肽Met-Ala-Lys对铜绿假单胞菌细胞膜的作用机制; Mechanism of Antibacterial Peptide Met-Ala-Lys Affecting on the Cytomembrane of Pseudomonas aeruginosa" "DRAMP37221" "SVAGRAQGM" "9" "Cn-AMP1" "No entry found" "Not found" "Not found" "Not found" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus CICC 23656 (MIC=500 µM), Staphylococcus epidermidis CICC 10294 (MIC=500 µM), Clostridium perfringens ATCC 13124 (MIC=500 µM), Bacillus cereus CICC 23828 (MIC=500 µM), Streptococcus pyogenes CICC 10373 (MIC=500 µM), Streptococcus faecalis CICC 23658 (MIC=250 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=500 µM),Pseudomonas aeruginosa CICC 21636 (MIC=500 µM),Salmonella Enteritidis CICC 21535 (MIC=500 µM),Klebsiella pneumonia ATCC 10031 (MIC=500 µM), Shigella baumannii ATCC 9027(MIC=500 µM), Enterobacter sakazakii CICC 21544(MIC=500 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "IC50 = 355.8 μM targeting on BEAS-2B cell cultured in DMEM-H medium containing 12% fetal bovine serum. The original article did not specify a positive control." "Cell membrane" "10.13819/j.issn.2096-708X.2021.05.001" "[J].齐齐哈尔医学院学报,2023,44(23):2208-2211." "陈柯,衣同辉,王宏兰,房丹丹,刘大鹏,高涵,潘洪明,李淑艳,王洁,刘桃源:Chen Ke,Yi Tonghui,Wang Honglan,Fang Dandan,Liu Dapeng,Gao Han,Pan Hongming,Li Shuyan,Wang Jie,Liu Taoyuan" "基于短链抗菌肽Cn-AMP1的拼接肽合成及抗菌活性研究; Study on synthesis and antibacterial activity of splicing peptides based on short chain antibacterial peptide Cn-AMP1" "DRAMP37222" "CLRIGMRGRELMGGIGKTM" "19" "h Glyrichin conserved domain peptide 1" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Polypeptide 1 (CLRIGMRGRELMGGIGKTM) containing h Glyrichin conserved domain and 19 amino acids in length was synthesized; then the GIG flexible fragment (GGIGKTM) formed by the 7 amino acids at the carboxyl terminus may not have antibacterial activity and was removed. Finally, polypeptide 2 (CLRIGMRGRELM) with a length of 12 amino acids was obtained." "Gram-positive bacteria: Staphylococcus aureus ATCC 26068, Staphylococcus aureus ATCC 25923##Gram-negative bacteria: Escherichia coli BL21, Salmonella typhimurium ATCC 460727." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7644/j.issn.1674-9960.2016.03.014" "[J].军事医学,2016,40(03):221-225." "沙继斌,赵光,张成岗:SHA Ji-bin,ZHAO Guang,ZHANG Cheng-gang" "人源性抗菌肽hGlyrichin中保守结构域肽段功能验证; Verification of conserved domain peptides derived from human antimicrobial peptide h Glyrichin" "DRAMP37223" "PFKLSLHL" "8" "P1(Lipopeptide designed by Jelleine-I)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: To evaluate the control effect of lipopeptide on citrus fruit green mildew, so as to provide theoretical basis for expanding the application range of antimicrobial peptide Jelleine-I and preventing and controlling citrus postharvest green mildew" "Fungus: Penicillium Digitatum" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "C10" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7506/spkx1002-6630-20190918-233" "[J].食品科学,2020,41(13):199-205." "李心丹,马佳宏,王文军,曾凯芳: LI Xindan,MA Jiahong,WANG Wenjun,ZENG Kaifang" "抗菌肽Jelleine-I的抑菌稳定性及Jelleine-I系列脂肽对柑橘果实绿霉病的控制效果; Stability of Antifungal Peptide Jelleine-I and Effect of Jelleine-I Lipopeptides on Controlling Citrus Postharvest Green Mold" "DRAMP37224" "KKVVFKVKFK" "10" "KSL" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Fusobacterium nucleatum 10953(MIC=0.0156mg/mL), Porphyromonas gingivalis 33277(MIC=0.125mg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13381/j.cnki.cjm.201407004" "[J].中国微生态学杂志,2014,26(07):760-763.DOI:10.13381/j.cnki.cjm.201407004." "李冀寅,那荣威,王一宇,隋馥勇,马国武,刘慧颖:LI Ji-yin,NA Rong-wei,WANG Yi-yu,SUI Fu-yong,MA Guo-wu,LIU Hui-ying" "抗菌肽对种植体周围炎主要致病菌生长抑制作用的研究; Inhibitory effect of antimicrobial peptides on peri-implantitis pathogens in vitro" "DRAMP37225" "SMWSGMWRRKLKKLRNALKKKLKGE" "25" "Latarcin-1" "No entry found" "Not found" "Not found" "L.tarabaevi" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37226" "FPFLLSLIPSAISALKKL" "18" "La39" "No entry found" "Belongs to the NDBPs family(NDBP:non-disulfide-bridged peptide)" "Not found" "Liocheles australasiae" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "La39 is α-helical polypeptide with high surface polarity and overall hydrophobicity" "Not found" "Comment: The cDNA library of scorpion venom gland was screened from Hainan Province." "Gram-positive bacteria: Staphylococcus aureus (MIC=50μg/mL)##Gram-negative bacteria: Escherichia coli (MIC>200μg/mL)" "HD50 = 99.6μg/mL against on human red blood cells . 1% Triton X-100 were used as the positive control." "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.3969/j.issn.2095-736.2022.01.033" "[J].生物学杂志,2022,39(01):33-36." "朱晨刚,贾庭:ZHU Chengang,JIA Ting" "蝎毒素抗菌肽La39的序列分析及功能鉴定; Functional identification and bioinformation analysis of antimicrobial peptide from scorpion venom" "DRAMP37227" "FKKVIVIRRWFI" "12" "ET12" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: ET12 is a useful and effective active peptide against gram-positive bacteria." "Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=64μg/mL), Staphylococcus epidermidis ATCC 12228 (MIC=8μg/mL), Staphylococcus epidermidis ATCC 35984 (MIC=16μg/mL)##Gram-negative bacteria: Acinetobacter baumannii aba 658 (MIC=256μg/mL), Acinetobacter baumannii aba 659 (MIC=32μg/mL), Acinetobacter baumannii aba 660 (MIC=64μg/mL), Acinetobacter baumannii aba 661 (MIC=128μg/mL), Acinetobacter baumannii aba 662 (MIC=128μg/mL), Pseudomonas aeruginosa ATCC 25922 (MIC>256μg/mL), Escherichia coli ATCC 25922 (MIC>256μg/mL), Klebsiella pneumoniae 1206 (MIC>256μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16016/j.1000-5404.202003346" "[J].第三军医大学学报,2020,42(15):1567-1572.DOI:10.16016/j.1000-5404.202003346." "袁慊,冯伟,王瑜,姚璞: YUAN Qian,FENG Wei,WANG Yu,YAO Pu,SUN Fengjun" "抗菌肽ET12对革兰阳性菌的抗菌活性及机制研究; Antibacterial activity and mechanism of antimicrobial peptide ET12 against Gram-positive bacteria" "DRAMP37228" "QAFQTFKPDWNKIRYDAMKMQTSLGQMKKRFNL" "33" "Latarcin-6a" "No entry found" "Not found" "Not found" "L.tarabaevi" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展: Advances in spider antimicrobial peptides" "DRAMP37229" "PFKLSLHL" "8" "P3(Lipopeptide designed by Jelleine-I)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: To evaluate the control effect of lipopeptide on citrus fruit green mildew, so as to provide theoretical basis for expanding the application range of antimicrobial peptide Jelleine-I and preventing and controlling citrus postharvest green mildew" "Fungus: Penicillium Digitatum" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "C14" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7506/spkx1002-6630-20190918-233" "[J].食品科学,2020,41(13):199-205." "李心丹,马佳宏,王文军,曾凯芳: LI Xindan,MA Jiahong,WANG Wenjun,ZENG Kaifang" "抗菌肽Jelleine-I的抑菌稳定性及Jelleine-I系列脂肽对柑橘果实绿霉病的控制效果; Stability of Antifungal Peptide Jelleine-I and Effect of Jelleine-I Lipopeptides on Controlling Citrus Postharvest Green Mold" "DRAMP37230" "LQHTTGALGHLI" "12" "Temporin-GHa" "No entry found" "Belongs to the Temporin family" "Not found" "Hylarana guentheri" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Methicillin-resistant Staphylococcus aureus ATCC 43300 (MIC=26.6μmol/L), Staphylococcus aureus ATCC 25923(MIC=6.8μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 44752 (MIC=13.3μmol/L)##Fungus: Candida albicans(MIC=26.6μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.15886/j.cnki.hdxbzkb.2016.0038." "[J].海南大学学报(自然科学版),2016,34(03):250-256.DOI:10.15886/j.cnki.hdxbzkb.2016.0038." "董柱,钟亨任,罗文杰,宋彦亭,邓世明,张英霞:Dong Zhu,Zhong Hengren,Luo Wenjie,Song Yanting,Deng Shiming,Zhang Yingxia" "海南产沼蛙皮肤temporin家族抗菌肽抗菌活性及稳定性研究; Antimicrobial Activities and Influential Factors of Temporin Family Antimicrobial Peptides Derived from Hylarana guentheri of Hainan" "DRAMP37231" "GRFFRFFFRFFRG" "13" "GF(Designed with GRX2RX3RX2RG as template)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: GF, GI, GA and GL all maintained α-helical structure in the cell membrane simulation environment, but showed random coiled morphology in PBS. GV was randomly curled in PBS and SDS, but showed a distinct α-helix structure in TFE. GW did not show α helix structure in the three solutions." "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=4μmol/L), Staphylococcus aureus ATCC 43300(MIC=4μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=4μmol/L), Bacillus subtilis CMCC 63501 (MIC=8μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=4μmol/L), Escherichia coli UB1005 (MIC=2μmol/L), S.Typhimurium ATCC 7731(MIC=4μmol/L), Pseudomonas aeruginosa 27853(MIC=8μmol/L), S.pullorum C7913(MIC=2μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.11843/j.issn.03666964.2019.04.012" "[J].畜牧兽医学报,2019,50(04):791-801." "徐欣瑶,董娜,李欣然,杨洋,王志华,单安山: XU Xinyao,DONG Na,LI Xinran,YANG Yang,WANG Zhihua,SHAN Anshan" "不同疏水性氨基酸对α-螺旋抗菌肽生物学活性的影响; Effect of Different Hydrophobic Amino Acids on Biological Activity of Alpha Helix Antimicrobial Peptides" "DRAMP37232" "RFRPPIRRPPIRPPFYPPFRPPIRPPIFPPIRPPFRPPLGPFP" "43" "Bac5(Bovine cathelicidin antimicrobial peptides)" "No entry found" "Not found" "Not found" "Fetal Bovine Serum" "Antimicrobial, Antibacterial" "Not found" "Random coil" "Not found" "Not found" "Comment: Bovine cathelicidin antimicrobial peptides can act on the cell wall or cell membrane of bacteria, thereby causing bacterial death." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.3969/j.issn.1008-7516.2019.01.008" "[J].河南科技学院学报(自然科学版),2019,47(01):37-42." "李杰,杭柏林,宁春妹,司素锦,张慧辉,胡建和:LI Jie,HANG Bolin,NING Chunmei,SI Sujin,ZHANG Huihui,HU Jianhe" "牛源cathelicidin类抗菌肽的生物信息学分析; Bioinformatic analysis of bovine cathelicidin antimicrobial peptides" "DRAMP37233" "HC" "2" "PG-YGT-M2" "No entry found" "Not found" "Not found" "Taraxacum mongolicum" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: This research is helpful for the development and utilization of Taraxacum mongolicum protein peptides and the production of new Taraxacum mongolicum antimicrobial peptides." "Gram-positive bacteria: Staphylococcus aureus##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13271/j.mpb.018.003388" "[J].分子植物育种,2020,18(10):3388-3394.DOI:10.13271/j.mpb.018.003388." "林贺,金平,杨培国,唐姗,张辉,尹春梅:Lin He,Jin Ping,Yang Peiguo,Tang Shan,Zhang Hui,Yin Chunmei" "蒲公英酶解抗菌肽的分析; Analysis of Antimicrobial Peptides in Taraxacum mongolicum Enzymatic Hydrolysis" "DRAMP37234" "RKGWFKAMKSIAKFIAKEKLKEHL" "24" "Lycosin-I" "No entry found" "Not found" "Not found" "L.singoriensis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37235" "FK" "2" "PG-YGT-M1(1)" "No entry found" "Not found" "Not found" "Taraxacum mongolicum" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: This research is helpful for the development and utilization of Taraxacum mongolicum protein peptides and the production of new Taraxacum mongolicum antimicrobial peptides." "Gram-positive bacteria: Staphylococcus aureus##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13271/j.mpb.018.003388" "[J].分子植物育种,2020,18(10):3388-3394.DOI:10.13271/j.mpb.018.003388." "林贺,金平,杨培国,唐姗,张辉,尹春梅:Lin He,Jin Ping,Yang Peiguo,Tang Shan,Zhang Hui,Yin Chunmei" "蒲公英酶解抗菌肽的分析; Analysis of Antimicrobial Peptides in Taraxacum mongolicum Enzymatic Hydrolysis" "DRAMP37236" "FLRRLWRVAKSLF" "13" "LP-M1(Derived from Lausporin-1)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Cationic α-helical antimicrobial peptide composed of 14 amino acid residues" "Not found" "Comment: Based on the Lausporin-1 sequence and using basic amino acid substitution method, four derivative peptides LP-M1, LP-M2, LP-M3 and LP-M4 were designed. Compared with the wild type, these peptides have better effects on the studied "ESKAPE" All pathogenic bacteria showed good antibacterial activity (MIC: 5-20 μg/mL), and the hemolytic activity of LP-M3 was significantly reduced." "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=5μmol/L), Staphylococcus aureus ATCC 25923(MIC=5μmol/L), Enterococcus faecalis ATCC 29212(MIC=10μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=20μmol/L, Escherichia coli ATCC 35218(MIC=10μmol/L), Pseudomonas aeruginosa ATCC 27853(MIC=20μmol/L), Klebsiella pneumoniae ATCC 27853(MIC=5μmol/L),acinetobacter baumannii ATCC 19606(MIC=5μmol/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13819/j.issn.2096-708X.2021.05.001" "[J].湖北医药学院学报,2021,40(05):441-445+453.DOI:10.13819/j.issn.2096-708X.2021.05.001." " 罗旭东,张凯月,蒋僡雯,黎方琰,陈宗运: LUO Xu-dong,ZHANG Kai-yue,JIANG Hui-wen,LI Fang-yan,CHEN Zong-yun" "基于蝎抗菌肽Lausporin-1设计衍生肽以优化其抗“ESKAPE”病原菌活性; Analogues Designed from Scorpion-Derived Peptide Lausporin-1Exhibit Improved Antimicrobial Activity Against ‘ESKAPE’ Pathogens" "DRAMP37237" "GWRKKIGKKIERVGQNTRDATIQAIGVAQQAANVAATLKGK" "41" "Cec4-1(Cec4 amino acid replacement peptide)" "No entry found" "Not found" "Not found" "Musca domestica" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Truncation causes Cec4 to lose its antibacterial activity. The antibacterial activity of Cec4-4 after amino acid substitution is twice as high as that of the parent peptide against each test bacteria. The antibacterial peptide has no hemolytic reaction in the human body at a concentration of 1 mg/mL." "Gram-negative bacteria: Acinetobacter baumannii, Klebsiella pneumoniae." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16519/j.cnki.1004-311x.2019.04.0056" "[J].生物技术,2019,29(04):330-335.DOI:10.16519/j.cnki.1004-311x.2019.04.0056." "彭建,赵行行,吴兆颖,王涛,尚小丽,国果: PENG Jian,ZHAO Xing-xing,WU Zhao-ying,WANG Tao,SHANG Xiao-li,GUO Guo" "抗菌肽Cec4的结构改造及抗菌活性研究; Structural modification and antibacterial related activity study of antimicrobial peptide Cec4" "DRAMP37238" "GLKDKFKSMGEKLKQYIQTWKAKF" "24" "Latarcin-4a" "No entry found" "Not found" "Not found" "L.tarabaevi" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37239" "GRVVRVVVRVVRG" "13" "GV(Designed with GRX2RX3RX2RG as template)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix(In TFE)" "Not found" "Not found" "Comment: GF, GI, GA and GL all maintained α-helical structure in the cell membrane simulation environment, but showed random coiled morphology in PBS. GV was randomly curled in PBS and SDS, but showed a distinct α-helix structure in TFE. GW did not show α helix structure in the three solutions." "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=4μmol/L), Staphylococcus aureus ATCC 43300(MIC=2μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=8μmol/L), Bacillus subtilis CMCC 63501 (MIC=4μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2μmol/L), Escherichia coli UB1005 (MIC=2μmol/L), S.Typhimurium ATCC 7731(MIC=4μmol/L), Pseudomonas aeruginosa 27853(MIC=8μmol/L), S.pullorum C7913(MIC=4μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.11843/j.issn.03666964.2019.04.012" "[J].畜牧兽医学报,2019,50(04):791-801." "徐欣瑶,董娜,李欣然,杨洋,王志华,单安山: XU Xinyao,DONG Na,LI Xinran,YANG Yang,WANG Zhihua,SHAN Anshan" "不同疏水性氨基酸对α-螺旋抗菌肽生物学活性的影响; Effect of Different Hydrophobic Amino Acids on Biological Activity of Alpha Helix Antimicrobial Peptides" "DRAMP37240" "DNTDSVVKIQSWFRMATARKSYL" "23" "2IQ3" "No entry found" "Not found" "Not found" "Homo sapiens " "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ##Gram-negative bacteria: Escherichia coli##Fungus: Candida albicans." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13885/j.issn.1000-2812.2015.03.004." "[J].兰州大学学报(医学版),2015,41(03):19-22.DOI:10.13885/j.issn.1000-2812.2015.03.004." "马驰,王玉平,谢俊秋,张雪燕,徐攀,杜振亚,倪天治,马如超,韩跃武:Ma Chi,Wang Yu-ping,Xie Jun-qiu,Zhang Xue-yan,Xu Pan,Du Zhen-ya,Ni Tian-zhi,Ma Ru-chao,Han Yue-wu " "抗菌肽2IQ3及其突变体的原核表达与纯化; Prokaryotic expression and purification of antimicrobial peptide 2IQ3 and its mutants" "DRAMP37241" "GFGALFKFLAKKVAKTVAKQAAKQGAKYVVNKQME" "35" "Cupiennin-1a" "No entry found" "Not found" "Not found" "C.salei" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37242" "GKFSVFGKILRSIAKVFKGVGKVRKQFKTASDLDKNQ" "37" "Oxyopinin-2a" "No entry found" "Not found" "Not found" "0.takobius" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37243" "MGQARGAVSMGQARGAVS" "18" "C2(Peptide derived from Cn-AMP1)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: The designed and synthesized peptides C2 and C4 had good antibacterial activity against gram-negative and gram-positive bacteria, and the activity was significantly improved compared with the parent peptides Cn-AMP1." "Gram-positive bacteria: Staphylococcus aureus CICC 23656 (MIC=8 µM), Staphylococcus epidermidis CICC 10294 (MIC=32 µM), Clostridium perfringens ATCC 13124 (MIC=16 µM), Bacillus cereus CICC 23828 (MIC=16 µM), Streptococcus pyogenes CICC 10373 (MIC=32 µM), Streptococcus faecalis CICC 23658 (MIC=8 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=32 µM),Pseudomonas aeruginosa CICC 21636 (MIC=32 µM),Salmonella Enteritidis CICC 21535 (MIC=8 µM),Klebsiella pneumonia ATCC 10031 (MIC=16 µM), Shigella baumannii ATCC 9027(MIC=32 µM), Enterobacter sakazakii CICC 21544(MIC=16 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "IC50 = 420.9 μM targeting on BEAS-2B cell cultured in DMEM-H medium containing 10% fetal bovine serum. The original article did not specify a positive control." "Cell membrane" "10.3969/j.issn.1002-1256.2023.23.002" "[J].齐齐哈尔医学院学报,2023,44(23):2208-2211." "陈柯,衣同辉,王宏兰,房丹丹,刘大鹏,高涵,潘洪明,李淑艳,王洁,刘桃源:Chen Ke,Yi Tonghui,Wang Honglan,Fang Dandan,Liu Dapeng,Gao Han,Pan Hongming,Li Shuyan,Wang Jie,Liu Taoyuan" "基于短链抗菌肽Cn-AMP1的拼接肽合成及抗菌活性研究; Study on synthesis and antibacterial activity of splicing peptides based on short chain antibacterial peptide Cn-AMP1" "DRAMP37244" "IKKLIKSAKWWLKIIA" "16" "MAF-1A16S5(Derived from MAF-1A)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: The derived peptide MAF-1A22S7 has obvious antifungal effect in vitro" "Fungus:Candida albican ATCC10231 (MIC=62.50 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19367/j.cnki.2096-8388.2023.01.004." "[J].贵州医科大学学报,2023,48(01):25-32.DOI:10.19367/j.cnki.2096-8388.2023.01.004." "黄敏慧,曾晔,张迎春,李彩多,吴建伟,陈峥宏,王涛: HUANG Minhui,ZENG Ye,ZHANG Yingchun,LI Caiduo,WU Jianwei,CHEN Zhenghong,WANG Tao" "抗菌肽MAF-1A洐生肽的设计及其抗白色念珠菌活性; Design of antibacterial peptide MAF-1A derivatives and their activity against Candida albicans" "DRAMP37245" "KKFKETADKLIESAKQQLESLAKEMK" "26" "MAF-1A" "No entry found" "Not found" "Not found" "Musca domestica" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Function: Bactericidal efficacy against many kinds of pathogenic Candida albicans and their drug-resistant strains, such as Candida albicans, and has the characteristics of low hemolytic activity and low cytotoxicity." "Fungus: Candida albicans" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19367/j.cnki.2096-8388.2021.12.002" "贵州医科大学学报,2021,46 (12):1370 - 1375,1388." "邓思波,黄敏慧,张迎春,吴建伟,崔古贞,陈峥宏,王涛: DENG Sibo,HUANG Minhui,ZHANG Yingchun,WU Jianwei,CUI Guzhen,CHEN Zhenghong,WANG Tao" "抗真菌肽-1A对白念珠菌细胞膜的作用; Effect of antifungal peptide-1A against Candida albicans membrane" "DRAMP37246" "NGKKKRKKPEKLCMKPGACSVIFDASVNE" "29" "BG-CATH29" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Random coil" "Not found" "Not found" "Comment: Through further mining of the measured transcriptome data, another cDNA encoding an antibacterial peptide of the Cathelicidin family of Bufo chinensis was discovered.By analyzing the processing methods of known antimicrobial peptides of the Cathelicidin family, the precursor cDNA may produce mature antimicrobial peptides BG-CATH25 and BG-CATH29." "Gram-negative bacteria: Aeromorus hydrophila(MIC=10mg/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.4268/cjcmm20160414" "[J].中国中药杂志,2016,41(04):630-635." "展波,高媛媛,林维平,贾广韬,孙同毅,李文辉:ZHAN Bo,GAO Yuan-yuan,LIN Wei-ping,JIA Guang-tao,SUN Tong-yi,LEE Wen-hui" "中华大蟾蜍皮肤Cathelicidin家族新型抗菌肽的鉴定及其抗菌活性; Identification and bactericidal activity of a novel Cathelicidin family member from skin of Bufu bufo gargarizans" "DRAMP37247" "WQLVPLAIKIYRAWKRR" "17" "Cath(4-20)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=2μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=4μmol/L), Enterococcus faecalis ATCC 29212(MIC=2μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=1μmol/L), Escherichia coli UB 1005(MIC=4μmol/L), Salmonella pullorum C79-13(MIC=4μmol/L), Salmonella typhimurium C77-31(MIC=2μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.3969/j.issn.1005-9369.2017.03.006" "[J].东北农业大学学报,2017,48(03):40-47.DOI:10.19720/j.cnki.issn.1005-9369.2017.03.006." "冯兴军,李丹,朱健,刘超群,高伟,陈惠娴:FENG Xingjun,LI Dan,ZHU Jian,LIU Chaoqun,GAO Wei,CHEN Huixian" "鸭抗菌肽Cathelicidin的衍生物设计及抑菌机制研究; Design of derivatives of duck antimicrobial peptide Cathelicidin and antibacterial mechanism" "DRAMP37248" "VRLLRRRI" "8" "SAMP1-A4(Derived from SAMP1)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "The secondary structure of SAMP1 and most similar peptides is dominated by α helix and random curling. In 54% (volume fraction) TFE solution, the proportion of alpha helix increases." "Not found" "Comment: The hydrophobic amino acid residues in SAMP1 sequence were replaced by isoleucine (Ile), valine (Val), leucine (Leu) and tryptophan (Trp), and the effect of hydrophobic change on the action of antimicrobial peptides was studied. At the same time, 8 new similar peptides were designed and synthesized by means of amino acid residue substitution and sequence rearrangement." "Gram-positive bacteria: Staphylococcus aureus (MIC=3.9μg/mL), Bacillus subtilis (MIC=0.95μg/mL), Listeria monocytogenes (MIC=0.95μg/mL)##Gram-negative bacteria: Candida tropicalis (MIC=3.9μg/mL), Escherichia coli (MIC=3.9μg/mL), Pseudomonas aeruginosa 27853(MIC=7.8μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7503/cjcu20180680" "[J].高等学校化学学报,2019,40(04):705-711." "常俊朋,赵佳瑞,陈思佳,孟凯,石微妮,李瑞芳:CHANG Junpeng,ZHAO Jiarui,CHEN Sijia,MENG Kai,SHI Weini,LI Ruifang" "抗菌肽SAMP1及其类似肽的构效关系; Structure-activity Relationship of Antimicrobial Peptide SAMP1 and Its Analog Peptides" "DRAMP37249" "FKRLLKSVRRAVKKF" "15" "Hc-15(Derived from Hc-CATH)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal" "Not found" "Amphipathic alpha helix structure" "Not found" "Not found" "Comment: The Hc-CATH amphiphilic α helix region was intercepted and a series of modifications were obtained by deleting N-terminal and C-terminal one by one." "Gram-positive bacteria: Staphylococcus aureus (CI) (MIC=4.69μg/mL), Nocardia asteroides(CI) (MIC=18.8μg/mL)##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=37.5μg/mL), Escherichia coli 1 (CIb) (MIC=18.8μg/mL), Escherichia coli 3 (CI) (MIC=37.5μg/mL), Shigella dysenteriae(CI) (MIC=4.69μg/mL), Proteus mirabilis (CI) (MIC=9.38μg/mL), Pseudomonas aeruginosa (CI) (MIC=37.5μg/mL), Pseudomonas aeruginosa 1 (CI) (MIC=4.69μg/mL), Salmonella paratyphi A (CI) (MIC=37.5μg/mL);##Fungus: Candida albicans(CI) (MIC=150μg/mL), Candida glabrata 1 (CI) (MIC=75μg/mL), Candida glabrata 2 (CI) (MIC=37.5μg/mL), Arcyria cinerea (CI) (MIC=18.9μg/mL)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13345/j.cjb.200583" "[J].生物工程学报,2021,37(07):2534-2542.DOI:10.13345/j.cjb.200583." "高久香,王义鹏,于海宁: Jiuxiang Gao,Yipeng Wang,Haining Yu" "青环海蛇抗菌肽Hc-CATH的分子设计及药效毒理优化; Molecular design, pharmacology and toxicology optimization of antimicrobial peptide from Hydrophis cyanocinctus, Hc-CATH" "DRAMP37250" "SLQPGAPQFPVPGQSNEGWSGSPNVERDEQGNTRTSINVQHKGNNHDFDAGWSKVIRGPAKAKPSWHVRGTYRW" "74" "Ap AMP1015" "No entry found" "Not found" "Not found" "Anatolica polita borealis" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16380/j.kcxb.2016.01.002." "[J].昆虫学报,2016,59(01):8-15.DOI:10.16380/j.kcxb.2016.01.002." "海力且木·艾力,徐鑫,刘忠渊:HAILIQIEMU AiLi,XU Xin,LIU Zhong-Yuan" "光滑鳖甲抗菌肽的原核表达条件优化及其抗菌活性; Optimization of prokaryotic expression conditions and the antibacterial activity of a novel antimicrobial peptide from Anatolica polita borealis(Coleoptera: Tenebrionidae)" "DRAMP37251" "VR" "2" "PG-YGT-T3" "No entry found" "Not found" "Not found" "Taraxacum mongolicum" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: This research is helpful for the development and utilization of Taraxacum mongolicum protein peptides and the production of new Taraxacum mongolicum antimicrobial peptides." "Gram-positive bacteria: Staphylococcus aureus##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13271/j.mpb.018.003388" "[J].分子植物育种,2020,18(10):3388-3394.DOI:10.13271/j.mpb.018.003388." "林贺,金平,杨培国,唐姗,张辉,尹春梅:Lin He,Jin Ping,Yang Peiguo,Tang Shan,Zhang Hui,Yin Chunmei" "蒲公英酶解抗菌肽的分析; Analysis of Antimicrobial Peptides in Taraxacum mongolicum Enzymatic Hydrolysis" "DRAMP37252" "VCSKMKLLKRPCQSIMKKFLRRI" "23" "NK7652-23" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Escherichia coli 25922 (MIC=31.25μg/mL), Salmonella typhimurium (MIC=62.5μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2017.09.028." "[J].中国畜牧兽医,2017,44(09):2739-2746.DOI:10.16431/j.cnki.1671-7236.2017.09.028." "杨霞,张殿卿,宋佳玮,肖盛中,盛金良,剡根强:YANG Xia,ZHANG Dian-qing,SONG Jia-wei,XIAO Sheng-zhong,SHENG Jin-liang,YAN Gen-qiang" "合成绵羊抗菌肽NK-Lysin抗菌活性及其对雏鸡沙门氏菌攻毒的治疗效果研究; Antimicrobial Activity of Synthesized Sheep NK-Lysin Peptides and Its Treatment for Chicken Salmonella Challenge" "DRAMP37253" "QLVPLAIKIYRAWKRR" "16" "Cath(5-20)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=2μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=4μmol/L), Enterococcus faecalis ATCC 29212(MIC=4μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=1μmol/L), Escherichia coli UB 1005(MIC=4μmol/L), Salmonella pullorum C79-13(MIC=8μmol/L), Salmonella typhimurium C77-31(MIC=4μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.3969/j.issn.1005-9369.2017.03.006" "[J].东北农业大学学报,2017,48(03):40-47.DOI:10.19720/j.cnki.issn.1005-9369.2017.03.006." "冯兴军,李丹,朱健,刘超群,高伟,陈惠娴:FENG Xingjun,LI Dan,ZHU Jian,LIU Chaoqun,GAO Wei,CHEN Huixian" "鸭抗菌肽Cathelicidin的衍生物设计及抑菌机制研究; Design of derivatives of duck antimicrobial peptide Cathelicidin and antibacterial mechanism" "DRAMP37254" "SWASMAKKLKEYMEKLKQRA" "20" "Latarcin-3b" "No entry found" "Not found" "Not found" "L.tarabaevi" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37255" "GLLLKLGKLLLKGLKK" "16" "LK" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Exhibits obvious α-helical structure in trifluoroethanol buffer" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 25923(MIC=2μmol/L), Staphylococcus aureus ATCC 29213(MIC=2μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=2μmol/L), Bacillus subtilis CMCC 63501(MIC=2μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=2μmol/L), Escherichia coli ATCC O78(MIC=4μmol/L), Salmonella pullorum C79-13(MIC=4μmol/L), Pseudomonas aeruginosa ATCC 27853(MIC=4μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13344/j.microbiol.china.130153" "[J].微生物学通报,2014,41(02):312-318.DOI:10.13344/j.microbiol.china.130153." "王良,马清泉,单安山,董娜,吕银凤:WANG Liang,MA Qing-Quan,SHAN An-Shan,DONG Na,Lü Yin-Feng" "利用亮氨酸和赖氨酸设计新型α-螺旋抗菌肽; Rational design of α-helical antimicrobial peptide with Leu and Lys residues" "DRAMP37256" "RRFKLLSHSLLVTLASHL" "18" "JH-3" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ##Gram-negative bacteria: Escherichia coli##Fungus: Candida albicans." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2017.01.008" "[J].中国畜牧兽医,2017,44(01):59-64.DOI:10.16431/j.cnki.1671-7236.2017.01.008." "李杰,杭柏林,秦爱建,钱琨,胡建和:LI Jie,HANG Bo-lin,QIN Ai-jian,QIAN Kun,HU Jian-he" "牛血红蛋白源抗菌肽P3及其类似肽的生物信息学分析; Bioinformatics Analysis of Antimicrobial Peptide P3 from Bovine Hemoglobin and Its Analogs" "DRAMP37257" "RKKRRQRRR" "9" "Tat (49-57)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: It is speculated that Tat (49-57) and its derived peptides inhibit bacterial growth by affecting the replication, inheritance and transcription functions of DNA through non-covalent binding to bacterial DNA." "Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=90.70μg/mL), Bacillus subtilis KCTC 3068 (MIC=34.84μg/mL)##Gram-negative bacteria: Escherichia coli 25922 (MIC=20.63μg/mL), Salmonella typhimurium CMCC 50013 (MIC=146.36μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "DNA" "10.6023/cjoc201708042" "[J].有机化学,2018,38(01):148-155." "吕名秀,买文鹏,卢奎,段冰潮,赵玉芬:Lü,Mingxiu Mai,Wenpeng Lu,Kui Duan,Bingchao Zhao,Yufen" "基于Tat(49-57)抗菌肽的设计、合成与性质研究; Design, Synthesis and Properties of the Antibacterial Peptides Based on Tat (49-57)" "DRAMP37258" "GLLKRIKTLLPINLKALAALAKKIL" "25" "AM- 3" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Alpha helix" "Not found" "Not found" "Comment: In order to further study the effect of Pro on the activity of antimicrobial peptides, an antimicrobial peptide AM-3 was designed and synthesized. The only difference from the previously designed and synthesized AM-4 with good anti-tumor activity and drug selectivity is the 11th position at the N-terminus. Bit, AM-3 is Pro, AM-4 is Ahx." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19286/j.cnki.cci.2019.01.037." "[J].煤炭与化工,2019,42(01):130-132.DOI:10.19286/j.cnki.cci.2019.01.037." "刘立伟,张荐益,孟丹,朱正煜:Liu Liwei,Zhang Jianyi,Meng Dan,Zhu Zhengyu" "Pro的引入对抗菌肽活性的影响研究; Effect of Pro introduction on antimicrobial peptide activity" "DRAMP37259" "GLLSKIKEVGGRIPACIA" "18" "DP" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Alpha helix" "Not found" "Not found" "Comment: Based on LL-37 or HNP-1 in the human body, according to the above-mentioned relevant parameter analysis, the active fragment of LL-37 is the amino acid sequence 10-17 and the active fragment of HNP-1 is the amino acid sequence 5-11, which is similar to Maximin. The active amino acid sequence fragments 1-8 and 11-17 of 1 and the active amino acid sequence fragments 1-9 of Dermaseptin-B2 are spliced ​​together through "-Glycine (Gly, G) Glycine (Gly, G) -", and the color The amino acid (Trp, W) is replaced with leucine (Leu, L) to increase the net charge of the peptide and synthesize a new hybrid peptide." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16050/j.cnki.issn1674-6309.2016.06.003" "[J].宁夏医科大学学报,2016,38(06):615-619+730.DOI:10.16050/j.cnki.issn1674-6309.2016.06.003." "陈香君,刘二强,回丽媛,朱明星,王秀青:CHEN Xiangjun,LIU Erqiang,HUI Liyuan,ZHU Mingxing,WANG Xiuqing" "新型抗肿瘤杂合抗菌肽的设计、合成及抗肿瘤活性研究; Design, Synthesis and Antitumor Research of New Antitumor Hybrid Antimicrobial Peptides" "DRAMP37260" "GBKRLVQRLKDBLRNLV" "17" "Merecidin (17BIPHE2) (Derived from LL-37)" "No entry found" "Not found" "Not found" "Homo sapiens (Human)" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Be superior to parent LL-37 in immune regulation and inhibition of various pathogens." "Gram-positive bacteria: Streptococcus gordonii" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.3872/j.issn.1007-385x.2020.11.005" "[J].中国肿瘤生物治疗杂志,2020,27(11):1229-1238." "贾琴琴,杨婷婷,王雅蓉,张倩楠,王秀青:JIA Qinqin,YANG Tingting,WANG Yarong,ZHANG Qiannan,WANG Xiuqing" "磷酸化蛋白质组学技术分析抗菌肽merecidin抑制人肺腺癌A549细胞增殖的作用机制; Phosphoproteomics analysis of the mechanism of antimicrobial peptide merecidin inhibiting the proliferation of lung adenocarcinoma A549 cells" "DRAMP37261" "FKKTAKKLIKSAKIWLISLAKI" "22" "MAF-1A 22S3(Derived from MAF-1A)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: The derived peptide MAF-1A22S4 has obvious antifungal effect in vitro" "Fungus:Candida albican ATCC10231 (MIC=31.25 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19367/j.cnki.2096-8388.2023.01.004." "[J].贵州医科大学学报,2023,48(01):25-32.DOI:10.19367/j.cnki.2096-8388.2023.01.004." "黄敏慧,曾晔,张迎春,李彩多,吴建伟,陈峥宏,王涛: HUANG Minhui,ZENG Ye,ZHANG Yingchun,LI Caiduo,WU Jianwei,CHEN Zhenghong,WANG Tao" "抗菌肽MAF-1A洐生肽的设计及其抗白色念珠菌活性; Design of antibacterial peptide MAF-1A derivatives and their activity against Candida albicans" "DRAMP37262" "PFKLSLHL" "8" "P2(Lipopeptide designed by Jelleine-I)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: To evaluate the control effect of lipopeptide on citrus fruit green mildew, so as to provide theoretical basis for expanding the application range of antimicrobial peptide Jelleine-I and preventing and controlling citrus postharvest green mildew" "Fungus: Penicillium Digitatum" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "C12" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7506/spkx1002-6630-20190918-233" "[J].食品科学,2020,41(13):199-205." "李心丹,马佳宏,王文军,曾凯芳: LI Xindan,MA Jiahong,WANG Wenjun,ZENG Kaifang" "抗菌肽Jelleine-I的抑菌稳定性及Jelleine-I系列脂肽对柑橘果实绿霉病的控制效果; Stability of Antifungal Peptide Jelleine-I and Effect of Jelleine-I Lipopeptides on Controlling Citrus Postharvest Green Mold" "DRAMP37263" "FLQHIIGALSHFF" "13" "Temporin-GHd" "No entry found" "Belongs to the Temporin family" "Not found" "Hylarana guentheri" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Methicillin-resistant Staphylococcus aureus ATCC 43300 (MIC=12.7μmol/L), Staphylococcus aureus ATCC 25923(MIC=12.7μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 44752 (MIC=12.7μmol/L)##Fungus: Candida albicans(MIC=25.5μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.15886/j.cnki.hdxbzkb.2016.0038." "[J].海南大学学报(自然科学版),2016,34(03):250-256.DOI:10.15886/j.cnki.hdxbzkb.2016.0038." "董柱,钟亨任,罗文杰,宋彦亭,邓世明,张英霞:Dong Zhu,Zhong Hengren,Luo Wenjie,Song Yanting,Deng Shiming,Zhang Yingxia" "海南产沼蛙皮肤temporin家族抗菌肽抗菌活性及稳定性研究; Antimicrobial Activities and Influential Factors of Temporin Family Antimicrobial Peptides Derived from Hylarana guentheri of Hainan" "DRAMP37264" "DV" "2" "PG-YGT-T1" "No entry found" "Not found" "Not found" "Taraxacum mongolicum" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: This research is helpful for the development and utilization of Taraxacum mongolicum protein peptides and the production of new Taraxacum mongolicum antimicrobial peptides." "Gram-positive bacteria: Staphylococcus aureus##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13271/j.mpb.018.003388" "[J].分子植物育种,2020,18(10):3388-3394.DOI:10.13271/j.mpb.018.003388." "林贺,金平,杨培国,唐姗,张辉,尹春梅:Lin He,Jin Ping,Yang Peiguo,Tang Shan,Zhang Hui,Yin Chunmei" "蒲公英酶解抗菌肽的分析; Analysis of Antimicrobial Peptides in Taraxacum mongolicum Enzymatic Hydrolysis" "DRAMP37265" "GRLQAFLAKMKEIAAQTL" "18" "Lycocitin-2" "No entry found" "Not found" "Not found" "L.singoriensis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37266" "FFRKKRRQRRR" "11" "Tat (FF)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Tat (49-57) derivative peptide" "Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=20.64μg/mL), Bacillus subtilis KCTC 3068 (MIC=14.62μg/mL)##Gram-negative bacteria: Escherichia coli 25922 (MIC=17.88μg/mL), Salmonella typhimurium CMCC 50013 (MIC=21.37μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "DNA" "10.6023/cjoc201708042" "[J].有机化学,2018,38(01):148-155." "吕名秀,买文鹏,卢奎,段冰潮,赵玉芬:Lü,Mingxiu Mai,Wenpeng Lu,Kui Duan,Bingchao Zhao,Yufen" "基于Tat(49-57)抗菌肽的设计、合成与性质研究; Design, Synthesis and Properties of the Antibacterial Peptides Based on Tat (49-57)" "DRAMP37267" "GFGSLFKFLAKKVAKTVAKQAAKQGAKYIANKQME" "35" "Cupiennin-1b" "No entry found" "Not found" "Not found" "C.salei" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37268" "PFKLSLHL" "8" "Jelleine-I" "No entry found" "Not found" "Not found" "Apis mellifera" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: To evaluate the control effect of lipopeptide on citrus fruit green mildew, so as to provide theoretical basis for expanding the application range of antimicrobial peptide Jelleine-I and preventing and controlling citrus postharvest green mildew" "Fungus: Penicillium Digitatum" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7506/spkx1002-6630-20190918-233" "[J].食品科学,2020,41(13):199-205." "李心丹,马佳宏,王文军,曾凯芳:LI Xindan,MA Jiahong,WANG Wenjun,ZENG Kaifang, " "抗菌肽Jelleine-I的抑菌稳定性及Jelleine-I系列脂肽对柑橘果实绿霉病的控制效果" "DRAMP37269" "SLKDKVKSMGEKLKQYIQTWKAKF" "24" "Latarcin-4b" "No entry found" "Not found" "Not found" "L.tarabaevi" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37270" "SCASRCKSRCRARRCKGYAAVSFGRRCICKCFRC" "34" "Mytilin-1" "No entry found" "Not found" "Not found" "Mytilus coruscus" "Antimicrobial, Antibacterial, Anti-Gram+" "Not found" "α-helix and two segments of β-folded strands and the β-hairpin structure connecting these two segments of β-folded strands" "α-helix and two segments of β-folded strands and the β-hairpin structure connecting these two segments of β-folded strands" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis, Staphylococcus aureus;##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Cyclic" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.3724/SP.J.1231.2010.06514" "水产学报,2010,34(01):153-159." "王日昕, 刘梅, 廖智,鲁涛 武梅 何光源:" "厚壳贻贝抗菌肽Mytilin的初步鉴定; Purification and identification of Mytilins from Mytilus coruscus" "DRAMP37271" "MWITNGGVANWYFVLAR" "17" "Cc AMP1" "No entry found" "Not found" "Not found" "Coridius chinensis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 25923(MIC=12.5μmol/L), Bacillus subtilis CMCC 63501(MIC=6.26μmol/L), Micrococcus luteus CMCC 28001(MIC=12.5μmol/L), Streptococcus pneumoniae ATCC 4961(MIC=6.26μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=6.26μmol/L), Pseudomonas solanacearum ATCC 33192(MIC=6.26μmol/L), Salmonella typhi CMCC 50071(MIC=3.13μmol/L), Shigella dysenteriae CMCC51252(MIC=1.57μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16380/j.kcxb.2015.06.004" "[J].昆虫学报,2015,58(06):610-616.DOI:10.16380/j.kcxb.2015.06.004." "李尚伟,赵柏松,杜娟:LI Shang-Wei,ZHAO Bai-Song,DU Juan" "九香虫抗菌肽CcAMP1的分离纯化和抗菌活性检测; Isolation,purification,and detection of the antimicrobial activity of the antimicrobial peptide CcAMP1 from Coridius chinensis(Hemiptera:Dinidoridae)" "DRAMP37272" "KWRRWVRWI" "9" "Pac-525" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Streptococcus sanguis 10556(MIC=0.1250mg/mL)##Gram-negative bacteria: Fusobacterium nucleatum 10953 (MIC=0.0078mg/mL), Porphyromonas gingivalis 33277 (MIC=0.0625mg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13381/j.cnki.cjm.201602008." "[J].中国微生态学杂志,2016,28(02):156-158+168.DOI:10.13381/j.cnki.cjm.201602008." "费涛,李冀寅,王一宇,何玉珠,马国武,刘慧颖:FEI Tao,LI Ji-yin,WANG Yi-yu,HE Yu-zhu,MA Guo-wu,LIU Hui-ying" "富含色氨酸抗菌肽对种植体周围炎主要致病菌生长抑制作用的研究; Inhibitory effect of tryptophan-rich antimicrobial peptides on peri-implantitis pathogens in vitro" "DRAMP37273" "GKFSVFSKILRSIAKVFKGVGKVRKQFKTASDLDKNQ" "37" "Oxyopinin-2d" "No entry found" "Not found" "Not found" "0.takobius" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/20140" "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing,CHEN Lian-Shui,LI Jiang" "蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides" "DRAMP37274" "GLLKRIKTLLKINLKALALAKKIL" "24" "AM-2" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: Two new antimicrobial peptides, AM-1 and AM-2, use Leu and Lys residues as linkers respectively to connect MP and Anoplin, forming a new antimicrobial peptide with 25 amino acid residues." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19286/j.cnki.cci.2018.11.043." "[J].煤炭与化工,2018,41(11):140-142.DOI:10.19286/j.cnki.cci.2018.11.043." "刘立伟,朱正煜,张荐益, 高腾超; Liu Liwei Zhu Zhengyu Zhang Jianyi Gao Tengchao" "2条新型抗菌肽的构效关系研究;Study on structure-activity relationship of two novel antibacterial peptides" "DRAMP37275" "MFTLKKSLLLLFFLGTISLSLCEEERNAEEERRDYPEERDVEVEKRIIPLPLGYFAKKT" "59" "dybowskin-1ST" "No entry found" "Not found" "Not found" "Rana dybowskii" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "26 amino acids participated in the formation of α-helix, accounting for 44.07%. 10 amino acids participated in the formation of the extended chain, accounting for 16.95%. Two amino acids participated in the formation of β-angle, accounting for 3.39%; 21 amino acids were involved in the formation of random curl, accounting for 35.39%.The secondary structure prediction showed that the protein was mainly α-helical." "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 6538 (MIC=0.75 µg/ml);##Gram-negative bacteria: Escherichia coli ATCC 43889(MIC=0.375 µg/ml), Pseudomonas aeruginosa CMCC 10104(MIC>1.5 µg/ml)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13345/j.cjb.200564." "[J].生物工程学报,2021,37(08):2890-2902.DOI:10.13345/j.cjb.200564." "刘悦,邵学超,王天添,王鑫莹,李南,赵云冬,夏薇,孙丽媛:Yue Liu,Xuechao Shao,Tiantian Wang,Xinying Wang,Nan Li,Yundong Zhao,Wei Xia,Liyuan Sun" "东北林蛙抗菌肽dybowskin-1ST的结构预测及生物学活性分析; Structure prediction and biological activity analysis of dybowskin-1ST antimicrobial peptide in Rana dybowskii" "DRAMP37276" "TRSSRAGLQFPVGRVHRLLRK" "21" "buforin Ⅱ" "No entry found" "Not found" "Not found" "Bufo bufo gargarizans" "Antimicrobial, Antibacterial, Antivirial" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16303/j.cnki.1005-4545.2015.07.17" "[J].中国兽医学报,2015,35(07):1119-1124.DOI:10.16303/j.cnki.1005-4545.2015.07.17." "唐志如,徐玲,石宝石,张小龙,邓欢,赖星,孙志洪:TANG Zhi-ru,XU Ling,SHI Bao-shi,ZHANG Xiao-long,DENG Huang,LAI Xin,SUN Zhi-hong" "日粮添加抗菌肽buforin Ⅱ对病毒性腹泻断奶仔猪小肠黏膜屏障和TLR-2信号途径的影响; Effects of dietary administered antibacterial peptide buforin Ⅱ on small intestinnal barrier and TLR-2 signal pathway in virus diarrhea weaned piglets" "DRAMP37277" "FKCRRWQWRMKKLGAVRRAF" "20" "Bovine lactoferricin(BLFcin)" "No entry found" "Not found" "Not found" "Bovine lactoferricin" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: An antimicrobial peptide derived from bovine lactoferrin (BLF)" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16476/j.pibb.2017.0256" "[J].生物化学与生物物理进展,2018,45(03):351-362.DOI:10.16476/j.pibb.2017.0256." "孔真真,赵立岭,唐艳,王吉华,曹赞霞:KONG Zhen-Zhen,ZHAO Li-Ling,TANG Yan,WANG Ji-Hua,CAO Zan-Xia" "抗菌肽BLFcin6与不同磷脂膜之间相互作用的分子动力学模拟研究;Study on The Interaction Between BLFcin6 and Different Phospholipid Membrane by Molecular Dynamics Simulation" "DRAMP37278" "CLRIGMRGRELM" "12" "h Glyrichin conserved domain peptide 2" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Polypeptide 1 (CLRIGMRGRELMGGIGKTM) containing h Glyrichin conserved domain and 19 amino acids in length was synthesized; then the GIG flexible fragment (GGIGKTM) formed by the 7 amino acids at the carboxyl terminus may not have antibacterial activity and was removed. Finally, polypeptide 2 (CLRIGMRGRELM) with a length of 12 amino acids was obtained." "Gram-positive bacteria: Staphylococcus aureus ATCC 26068, Staphylococcus aureus ATCC 25923##Gram-negative bacteria: Escherichia coli BL21, Salmonella typhimurium ATCC 460727." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7644/j.issn.1674-9960.2016.03.014" "[J].军事医学,2016,40(03):221-225." "沙继斌,赵光,张成岗:SHA Ji-bin ZHAO Guang ZHANG Cheng-gang" "人源性抗菌肽hGlyrichin中保守结构域肽段功能验证; Verification of conserved domain peptides derived from human antimicrobial peptide h Glyrichin" "DRAMP37279" "GIGKFLHSAKKFGKAFVGEIMNS" "23" "MagaininⅡ" "No entry found" "Not found" "Not found" "Xenopus laevis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16476/j.pibb.2017.0256" "[J].生物技术,2014,24(04):75-79." "成娟丽,李锋,王红,林金水:CHENG Juan-li,LI Feng,WANG Hong,LIN Jin -shui" "抗菌肽MagaininⅡ多拷贝串联体的设计与构建; Design and Construction of Concatemer of Antibacterial Peptide MagaininⅡ" "DRAMP37280" "LLRHVVKILEKYL" "13" "RGD-T-La(RGD-chimera peptide)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: Conjugate RGD to synthesize polypeptide RGD-chimera to increase the targeting effect of anti-tumor peptide on tumor cells" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "RGD" "None" "L" "No cytotoxicity information found" "Not found" "10.13200/j.cnki.cjb.002626" "[J].中国生物制品学杂志,2019,32(09):987-992.DOI:10.13200/j.cnki.cjb.002626." "张秋利,刘梦月,姜轩,金天明,赵瑞利,,马吉飞: ZHANG Qiu-li,LIU Meng-yue,JIANG Xuan,JIN Tian-ming,ZHAO Rui-li,MA Ji-fei,FU Chao,SHANG Zi-yu" "新抗菌肽RGD-嵌合体靶向抗黑色素瘤活性; Antitumor activity of a novel antibacterial peptide RGD-chimera targeting melanoma" "DRAMP37281" "GKLKKIGKKIERVGQNTRDATIQAIGVAQQAANVAATLKGK" "41" "Cec4-2(Cec4 amino acid replacement peptide)" "No entry found" "Not found" "Not found" "Musca domestica" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Truncation causes Cec4 to lose its antibacterial activity. The antibacterial activity of Cec4-4 after amino acid substitution is twice as high as that of the parent peptide against each test bacteria. The antibacterial peptide has no hemolytic reaction in the human body at a concentration of 1 mg/mL." "Gram-negative bacteria: Acinetobacter baumannii, Klebsiella pneumoniae." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16519/j.cnki.1004-311x.2019.04.0056" "[J].生物技术,2019,29(04):330-335.DOI:10.16519/j.cnki.1004-311x.2019.04.0056." "彭建,赵行行,吴兆颖,王涛,尚小丽,国果: PENG Jian,ZHAO Xing-xing,WU Zhao-ying,WANG Tao,SHANG Xiao-li,GUO Guo" "抗菌肽Cec4的结构改造及抗菌活性研究; Structural modification and antibacterial related activity study of antimicrobial peptide Cec4" "DRAMP37282" "GLTRLRRILFRLLLWRTK" "18" "CaDef2.1G27-K44" "No entry found" "Not found" "Not found" "Capsicum annuum" "Antimicrobial, Antibacterial, Anti-Gram-, Antifungal" "Protein level" "Alpha helix" "Enriched with turns and disordered conformations(59–61%) in aqueous solution and the presence of POPC." "Not found" "Function: CaDef2.1G27-K44 has great antimicrobial activity against Candidaspp. and M. tuberculosis with low toxicity to host cells." "Gram-positive bacteria: Mycobacterium tuberculosis H37Rv (MIC50= 33.2 µM), Mycobacterium tuberculosis M299 (MIC50= 55.4 µM);##Fungus: Candida tropicalis(CE017) (MIC100= 50 µM), Candia Parapsilosis(CE002) (MIC100= 50 µM), Candida albicans(CE022) (MIC100= 25 µM), Candida buinensis(3982) (MIC100= 25 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "CC50 >200 μM targeting on macrophages and monocytes. 1%(v/v) Triton X-100 detergent at 37 ℃ for 1 h was used as the positive control." "Cell membrane" "10.1016/J.BBAGEN.2022.130218" "Biochimica et Biophysica Acta (BBA) - ISSN 0304-4165." "Gabriel Bonan Taveira, Érica de Oliveira Mello, Thatiana Lopes Biá Ventura Simão, Milena Bellei Cherene, André de Oliveira Carvalho, Michelle Frazão Muzitano, Elena Lassounskaia, Saulo Pireda, Emílio de Castro Miguel, Luis Guilherme Mansor Basso, Maura Da Cunha, Olney Vieira da Motta, Valdirene Moreira Gomes." "A new bioinspired peptide on defensin from C. annuum fruits: Antimicrobial activity, mechanisms of action and therapeutical potential" "DRAMP37283" "RKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIXRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKR" "109" "SPC13" "No entry found" "Not found" "Not found" "Scolopendra Polymorpha" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 29212 (MIC=45 µM);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=192.5 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.2174/2211352517666190531110829" "Anti-Infective Agents. 2020. PP 233-238" "Rodríguez-Alejandro, Gutiérrez M.C." "Antimicrobial Activity of SPC13, New Antimicrobial Peptide Purified from Scolopendra polymorpha Venom" "DRAMP37284" "DGRCGGKLAKLAKKLAKLAK" "20" "CGAK" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13753/j.issn.1007-6611.2017.11.013" "[J].山西医科大学学报,2017,48(11):1149-1153.DOI:10.13753/j.issn.1007-6611.2017.11.013." "侯磊,岳晨莉,何莉,贾辉,白俊: HOU Lei,YUE Chenli,HE Li,JIA Hui,BAI Jun" "连接链对包含CisoDGRC结构抗菌肽诱导乳腺癌细胞凋亡的影响; Effect of connection chain on apoptosis induced by antibacterial peptide containing CisoDGRC in breast cancer cells" "DRAMP37285" "MHCLKIMAFLLFFSLLLSQVYCASLHQPQPLLRLKRMTPFWRGVSLRPVGASCRDNSECITMLCRKNRCFLRTASE" "76" "LEAP-2" "No entry found" "Not found" "Not found" "Gallus domestiaus" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "rich" "α-helix (36 amino acid residues involved) accounts for 47.31%, extended chain (9 amino acid residues participate) accounts for 11.84%, β-turn (6 amino acid residues participates) accounts for 7.89%, random coil (25 amino acid residues participate) base participation) accounted for 32.89%" "Not found" "Comment: No comments found on DRAMP database" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.15889/j.issn.1002-1302.2018.06.012" "[J].江苏农业科学,2018,46(06):46-50.DOI:10.15889/j.issn.1002-1302.2018.06.012." "杭柏林,徐军,胡建和:Hang Bolin" "鸡内源性抗菌肽LEAP-2的生物信息学分析; Bioinformatics analysis of endogenous antimicrobial peptide LEAP-2 of chicken" "DRAMP37286" "CRSWCKRPGHPEKNAFYCC" "19" "SpCrus1a29-47" "No entry found" "Not found" "Not found" "Scylla paramamosain" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus CGMCC 1.363 (MIC=6-12 µM);Micrococcus luteus CGMCC 1.290 (MIC=6-12 µM)##Gram-negative bacteria: Escherichia coli CGMCC 1.2389 (MIC>48 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "WAP domain(8 conserved cysteines)" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.6043/j.issn.0438-0479.201808007" "j.issn.0438-0479" "王晓飞,彭会,陈芳奕,张财亮,黄文树:WANG Xiaofei,PENG Hui,CHEN Fangyi,ZHANG Cailiang,HUANG Wenshu" "拟穴青蟹抗菌肽Crustin新变体的表达特性与抗菌功能;Characterization of expression and antimicrobial activity of a novel Crustin isoform from Scylla paramamosain" "DRAMP37287" "PFKLSLHL" "8" "P5(Lipopeptide designed by Jelleine-I)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: To evaluate the control effect of lipopeptide on citrus fruit green mildew, so as to provide theoretical basis for expanding the application range of antimicrobial peptide Jelleine-I and preventing and controlling citrus postharvest green mildew" "Fungus: Penicillium Digitatum" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Cinnamic acid(cin)" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7506/spkx1002-6630-20190918-233" "[J].食品科学,2020,41(13):199-205." "李心丹,马佳宏,王文军,曾凯芳: LI Xindan,MA Jiahong,WANG Wenjun,ZENG Kaifang" "抗菌肽Jelleine-I的抑菌稳定性及Jelleine-I系列脂肽对柑橘果实绿霉病的控制效果; Stability of Antifungal Peptide Jelleine-I and Effect of Jelleine-I Lipopeptides on Controlling Citrus Postharvest Green Mold" "DRAMP37288" "MAAALIVLLALGAAVQVAVTEPPRDDHRDLDAGSHWEQQWHLLQDGSAAWDADEGDAMGPGKGIKCRFCVSLVKKVQKIVGGSAAWDADEGDAMGPGKGIKCRFCVSLVKKVQKIVGDDPDEDAINNALNKVCSTGRRQRSICKQLLKKLRQQLSDALQNNDDPRDVCTTLGLCKG" "176" "NK-lysin" "No entry found" "Not found" "Not found" "pullus" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-,Anti-tumor, Anti-parasitic" "Not found" "Not found" "Not found" "Not found" "Comment: Homology analysis showed that the homology between domestic antimicrobial peptide NK-lysin and domestic granolysin was 100%. In fact, the antimicrobial peptide NK-lysin and granulysin are the same substance, which is isolated from humans and named granulysin (GNLY), while the granulysin isolated from the intestinal tract of pigs is similar to that of humans and has antibacterial function, and named NK-lysin (NKL)." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13881/j.cnki.hljxmsy2018.07.0256" "[J].黑龙江畜牧兽医,2019(15):86-89.DOI:10.13881/j.cnki.hljxmsy.2018.07.0256." "杭柏林,宁春妹,张炜,张慧辉,徐彦召,胡建和:HANG Bolin,NING Chunmei,ZHANG Wei,ZHANG Huihui,XU Yanzhao,HU Jianhe" "鸡抗菌肽NK-lysin的B细胞表位、剪切位点、疏水性及进化分析;B cell epitope, splicing site, hydrophobicity and evolutionary analysis of chicken antimicrobial peptide NK-lysin" "DRAMP37289" "KIWKFLKKAPPTEKLFKWIK" "20" "KK-20(Derived from MSI-1)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Antibacterial peptide KK-20 has broad-spectrum antibacterial activity against Candida albicans and Cryptococcus neoformans, but Candida albicans ATCC10231 has poor sensitivity to antibacterial peptide KK-20. There is no such phenomenon when treated with amphotericin B, which is due to the unique binding mechanism of the drug and ergosterol." "Fungus: Candida albicans ATCC 10231 (MIC=128μg/mL), Candida neoformans ATCC4096 (MIC=16μg/mL), Candida neoformans (MIC=8μg/mL), Candida albicans (MIC=32μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19526/j.cnki.1005-8915.20190304." "[J].药物生物技术,2019,26(03):204-210.DOI:10.19526/j.cnki.1005-8915.20190304." "史翔宇,杨晓倩,蒋美玲,黄亚,吴皓旻,马菱蔓,周长林:SHI Xiang-yu,YANG Xiao-qian,JIANG Mei-ling,HUANG Ya,WU Hao-min,MA Ling-man,ZHOU Chang-lin" "白色念珠菌与新生隐球菌对抗菌肽KK-20的敏感性差异研究;Study on the Sensitivity Difference between C. Albicans and C. Neoformans against Antibacterial Peptide KK-20" "DRAMP37290" "KLLRHRLLVTLA" "12" "JH-1" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Random coil" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2017.01.008" "[J].中国畜牧兽医,2017,44(01):59-64.DOI:10.16431/j.cnki.1671-7236.2017.01.008." "李杰,杭柏林,秦爱建,钱琨,胡建和:LI Jie,HANG Bo-lin,QIN Ai-jian,QIAN Kun,HU Jian-he" "牛血红蛋白源抗菌肽P3及其类似肽的生物信息学分析; Bioinformatics Analysis of Antimicrobial Peptide P3 from Bovine Hemoglobin and Its Analogs" "DRAMP37291" "GLLKRIKTLL- Ahx- INLKALAALAKKIL" "25" "AM- 4(Derived from AM- 3)(Ahx:aminocaproic acid)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Alpha helix" "Not found" "Not found" "Comment: In order to further study the effect of Pro on the activity of antimicrobial peptides, an antimicrobial peptide AM-3 was designed and synthesized. The only difference from the previously designed and synthesized AM-4 with good anti-tumor activity and drug selectivity is the 11th position at the N-terminus. Bit, AM-3 is Pro, AM-4 is Ahx." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19286/j.cnki.cci.2019.01.037." "[J].煤炭与化工,2019,42(01):130-132.DOI:10.19286/j.cnki.cci.2019.01.037." "刘立伟,张荐益,孟丹,朱正煜:Liu Liwei,Zhang Jianyi,Meng Dan,Zhu Zhengyu" "Pro的引入对抗菌肽活性的影响研究; Effect of Pro introduction on antimicrobial peptide activity" "DRAMP37292" "VRFKLLSHSLLVTLASHL" "18" "JH-2" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ##Gram-negative bacteria: Escherichia coli##Fungus: Candida albicans." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2017.01.008" "[J].中国畜牧兽医,2017,44(01):59-64.DOI:10.16431/j.cnki.1671-7236.2017.01.008." "李杰,杭柏林,秦爱建,钱琨,胡建和:LI Jie,HANG Bo-lin,QIN Ai-jian,QIAN Kun,HU Jian-he" "牛血红蛋白源抗菌肽P3及其类似肽的生物信息学分析; Bioinformatics Analysis of Antimicrobial Peptide P3 from Bovine Hemoglobin and Its Analogs" "DRAMP37293" "TFFRLFNRSFTQALGKGGGLLGDFFRKSKEKJGKEFKRIVQRIKDFLRNLVPRTES" "56" "C16LL-37" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: CSPC16, a polypeptide composed of the C-terminal 16 amino acids of S. mutans competent stimulating peptide (CSP), and their recombinant polypeptide C16LL-37." "Gram-positive bacteria: Staphylococcus aureus ATCC 25923(MIC=64μmol/L), Lactobacillus acidophilus ATCC 4356(MIC>128μmol/L), Viscous Actinomycetes ATCC 25175(MIC=64μmol/L), streptococcus mutans ATCC 25175(MIC=16μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=64μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.7518/hxkq.2016.03.016" "[J].华西口腔医学杂志,2016,34(03):295-301." "车春晓,姜科宇,马媛媛,曾飒,周建业,李志强,何祥一: Che Chunxiao,Jiang Keyu,Ma Yuanyuan,Zeng Sa,Zhou Jianye,Li Zhiqiang,He Xiangyi" "针对变异链球菌的人源特异性靶向抗菌肽C16LL-37的生物学特性; Biological characteristics of a human specifically targeted antimicrobial peptide C16LL-37 against Streptococcus mutans" "DRAMP37294" "ILPWKWPWWPWRR" "13" "Indolicidin" "No entry found" "Not found" "Not found" "Bovine" "Antimicrobial, Antibacterial, Antivirial" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.15889/j.issn.1002-1302.2017.07.010. " "[J].江苏农业科学,2017,45(07):44-46.DOI:10.15889/j.issn.1002-1302.2017.07.010." "武慧,宋明霞,宁思淇" "紫花苜蓿的抗菌肽基因Rev4遗传转化" "DRAMP37295" "FLPFFAACAITKKC" "14" "AMP-1" "No entry found" "Not found" "Not found" "Rana chensinensis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 29293." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13881/j.cnki.hljxmsy.2016.1018. " "[J].黑龙江畜牧兽医,2016(11):229-233.DOI:10.13881/j.cnki.hljxmsy.2016.1018." "王雅丽,蔡玉峰,郝镯" "中国林蛙皮肤抗菌肽的分离、纯化及序列分析" "DRAMP37296" "IWLTALKFLGKHAAKHLAKQQLSKL" "25" "Lycotoxin-1" "No entry found" "Not found" "Not found" "H.carolinensis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37297" "GKFSGFAKILKSIAKFFKGVGKVRKQFKEASDLDKNQ" "37" "Oxyopinin-2b" "No entry found" "Not found" "Not found" "0.takobius" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江: TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37298" "LFGKLIKKFGRKAISYAVKKARGKH" "25" "Latarcin-2a" "No entry found" "Not found" "Not found" "L.tarabaevj" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江: TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37299" "GFGSLFKFLAKKVAKTVAKQAAKQGAKYIANKQTE" "35" "Cupiennin-1c" "No entry found" "Not found" "Not found" "C.salei" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37300" "SWKSMAKKLKEYMEKLKQRA" "20" "Latarcin-3a" "No entry found" "Not found" "Not found" "L.tarabaevi" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37301" "FRGLAKLLKIGLKSFARVLKKVLPKAAKAGKALAKSMADENAIRQQNQ" "48" "Oxyopinin-1" "No entry found" "Not found" "Not found" "o.takobius" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37302" "GKLQAFLAKMKEIAAQTL" "18" "Lycocitin-1" "No entry found" "Not found" "Not found" "L.singoriensis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37303" "GFGSLFKFLAKKVAKTVAKQAAKQGAKYVANKHME" "35" "Cupiennin-1d" "No entry found" "Not found" "Not found" "C.salei" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37304" "GFFGKMKEYFKKFGASFKRRFANLKKRL" "28" "Latarcin-5" "No entry found" "Not found" "Not found" "L.tarabaevi" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37305" "GKLSGISKVLRAIAKFFKGVGKARKQFKEASDLDKNQ" "37" "Oxyopinin-2c" "No entry found" "Not found" "Not found" "0.takobius" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37306" "KIKWFKTMKSLAKFLAKEQMKKHLGE" "26" "Lycocitin-3" "No entry found" "Not found" "Not found" "L.singoriensis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis ##Gram-negative bacteria:Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014156. " "[J].生命科学,2014,26(10):1090-1095.DOI:10.13376/j.cbls/2014156." "唐兴,陈连水,李江:TANG Xing CHEN Lian-Shui LI Jiang " "蜘蛛抗菌肽研究进展:Advances in spider antimicrobial peptides" "DRAMP37307" "GVITDALKGAAKTVAAELLRKAHCKLTNSC" "30" "brevinin-2GHb" "No entry found" "Not found" "Not found" "Hylarana guentheri" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Under the action of TFE, the antimicrobial peptide folds from random coils into an α-helical structure." "Not found" "Comment: The Ile3-Arg20 fragment of brevinin-2GHb folds into an amphipathic α-helical structure in a simulated membrane environment. It is speculated that the possible antibacterial mechanism of brevinin-2GHb is: the positively charged brevinin-2GHb interacts with the negatively charged brevinin-2GHb electrostatically. Binds to the surface of the bacterial cell membrane and folds into an amphipathic α-helical structure in the hydrophobic environment of the cell membrane. This structure can destroy the stability and integrity of the cell membrane, allowing intracellular ions and nutrients to extravasate or antimicrobial peptides to enter the cytoplasm. , causing the cells to lyse and die." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13376/j.cbls/2014164. " "[J].福州大学学报(自然科学版),2015,43(03):405-410." "叶南慧,俞世宏,陈涛涛:YE Nanhui YU Shihong CHEN Taotao HONG Jing " "沼水蛙抗菌肽brevinin-2GHb结构研究:Study on structure of brevinin-2GHb, an antimicrobial peptide from Hylarana guentheri" "DRAMP37308" "GIGKFLHSAKKFPVPIIYCNRRTGKCQRM" "29" "Magainin-Thanatin (MT)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+" "Not found" "Not found" "The secondary structure mainly contains α-helices (h), accounting for 20.69%; extended chains (e), accounting for 24.14%; β-sheets (t), accounting for 10.34%; and random coils (c), accounting for 44.83%." "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus(MIC=16.5μM), Bacillus subtilis (MIC=9μM)##Gram-negative bacteria: Escherichia coli DH5α(MIC=20μM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19481/j.cnki.issn2096-398x.2018.03.013. " "[J].陕西科技大学学报,2018,36(03):68-77.DOI:10.19481/j.cnki.issn2096-398x.2018.03.013." "龚国利,张帝,苏鹏:GONG Guo-li ZHANG Di SU Peng WEI Yuan " "杂合抗菌肽MT在大肠杆菌中的融合表达;Fusion expressing of magainin and thanatin hybrid antibacterial peptide in Escherichia coli" "DRAMP37309" "KWKLFKKINWKKIGAVVKKIL" "21" "KL-21(Primary structure based on Mastoparan and Cecropin A)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial,Anti-Gram- " "Not found" "Not found" "Not found" "Not found" "Comment: Primary structure based on Mastoparan and Cecropin A" "Gram-positive bacteria:listeria monocytogenes,ATCC 19115 (MIC=16.0 µM)##Gram-negative bacteria: Salmonella Paratyphi B CMCC 50094 (MIC=32.0 µM), Pseudomonas aeruginosa CMCC 10104 (MIC=16.0 µM)##Fungus: Candida albicans,CMCC 98001 (MIC=16.0 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13302/j.cnki.fi.2024.12.018. " "[J/OL].饲料工业:1-7[2024-03-18]." "韩晋辉,翟培,吕文平: HAN Jinhui ZHAI Pei LYU Wenping LI Routing LIN Jin " "杂合抗菌肽KL-21与抗生素体外协同抗菌效果研究:Research on Synergistic Antibacterial Effect of Hybrid Antimicrobial Peptide KL-21 and Antibiotics In Vitro" "DRAMP37310" "SGFIPLKPTVK" "11" "A2M3" "No entry found" "Belongs to the α2-macroglobulin receptor domain family (RBD)" "Not found" "Homo sapiens (Human)" "Antimicrobial, Antibacterial, Anti-Gram+" "Not found" "Rich" "β-sandwich domain composed of multiple β-layers" "Not found" "Function: Peptide A2M3 can not only effectively kill Staphylococcus aureus, but also reduce the cost of synthetic peptide without drug resistance." "Gram-positive bacteria: Staphylococcus aureus(MIC=125.0 µM)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13343/j.cnki.wsxb.20230637. " "Acta Microbiologica Sinica ISSN 0001-6209,CN 11-1995/Q" "范学楠,林蓉,金日天,梁铎,邱绪健,杨燊: FAN Xuenan LIN Rong JIN Ritian LIANG Duo QIU Xujian YANG Shen " "一种源自人α-2-巨球蛋白的抗菌肽 A2M3 及其对金黄色葡萄球菌的抑菌机制:A novel antimicrobial peptide A2M3 derived from human alpha-2-macroglobulin inhibits Staphylococcus aureus" "DRAMP37311" "FWQLVPLAIKIYRAWKRR" "18" "Cath(3-20)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=2μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=1μmol/L), Enterococcus faecalis ATCC 29212(MIC=2μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=1μmol/L), Escherichia coli UB 1005(MIC=2μmol/L), Salmonella pullorum C79-13(MIC=2μmol/L), Salmonella typhimurium C77-31(MIC=4μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19720/j.cnki.issn.1005-9369.2017.03.006. " "[J].东北农业大学学报,2017,48(03):40-47.DOI:10.19720/j.cnki.issn.1005-9369.2017.03.006." "冯兴军,李丹,朱健: FENG Xingjun LI Dan ZHU Jian LIU Chaoqun GAO Wei CHEN Huixian " "鸭抗菌肽Cathelicidin的衍生物设计及抑菌机制研究:Design of derivatives of duck antimicrobial peptide Cathelicidin and antibacterial mechanism" "DRAMP37312" "KRFWQLVPLAIKIYRAWKRR" "20" "Cath(1-20)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=4μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=4μmol/L), Enterococcus faecalis ATCC 29212(MIC=4μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=2μmol/L), Escherichia coli UB 1005(MIC=2μmol/L), Salmonella pullorum C79-13(MIC=4μmol/L), Salmonella typhimurium C77-31(MIC=8μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19720/j.cnki.issn.1005-9369.2017.03.006. " "[J].东北农业大学学报,2017,48(03):40-47.DOI:10.19720/j.cnki.issn.1005-9369.2017.03.006." "冯兴军,李丹,朱健:FENG Xingjun LI Dan ZHU Jian LIU Chaoqun GAO Wei CHEN Huixian " "鸭抗菌肽Cathelicidin的衍生物设计及抑菌机制研究:Design of derivatives of duck antimicrobial peptide Cathelicidin and antibacterial mechanism" "DRAMP37313" "EPRWKVFKKIEKMGRNIRDGIIKAGPAVAVLGDAKALGK" "39" "AAP-1" "No entry found" "Not found" "Not found" "Mythimna seperata" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: A novel myxoid antimicrobial peptide was identified by transcriptome sequencing and sequence analysis." "Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=7.8μg/mL)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2020.11.025. " "[J].中国畜牧兽医,2020,47(11):3626-3632.DOI:10.16431/j.cnki.1671-7236.2020.11.025." "连凯琪,周玲玲,张元臣: LIAN Kaiqi ZHOU Lingling ZHANG Yuanchen SHI Zhiqi LIN Zhengdan SONG Yuwei WANG Shuangshan ZHANG Mingliang " "新型黏虫抗菌肽AAP-1对大肠杆菌的抗菌作用:Antibacterial Effect of Novel Armyworm Antimicrobial Peptide (AAP-1) Against Escherichia coli" "DRAMP37314" "RIVELTLPRVSVRL" "14" "Crude mucus extract from catfish body surface(Fragment 2) (author unnamed)" "No entry found" "Not found" "Not found" "Clarias fuscus" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Alpha helix" "Typical α-helical structure in 2.5%SDS solution" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Shewanella putrefaciens, Shewanella putrefaciens." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16429/j.1009-7848.2020.08.010. " "[J].中国食品学报,2020,20(08):84-91.DOI:10.16429/j.1009-7848.2020.08.010." "刘权伟,李婷婷,励建荣: Liu Quanwei Li Tingting Li Jianrong " "新型鲶鱼体表黏液抗菌肽抑菌活性验证及抑菌机理:Validation of Antimicrobial Activity of Antibacterial Peptides from New Type Catfish Epidermal Mucus and Its Antimicrobial Mechanism" "DRAMP37315" "GLLSKIKEVGGKTALKGA" "18" "DM" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Alpha helix" "Not found" "Not found" "Comment: Based on LL-37 or HNP-1 in the human body, according to the above-mentioned relevant parameter analysis, the active fragment of LL-37 is the amino acid sequence 10-17 and the active fragment of HNP-1 is the amino acid sequence 5-11, which is similar to Maximin. The active amino acid sequence fragments 1-8 and 11-17 of 1 and the active amino acid sequence fragments 1-9 of Dermaseptin-B2 are spliced ​​together through "-Glycine (Gly, G) Glycine (Gly, G) -", and the color The amino acid (Trp, W) is replaced with leucine (Leu, L) to increase the net charge of the peptide and synthesize a new hybrid peptide." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16050/j.cnki.issn1674-6309.2016.06.003. " "[J].宁夏医科大学学报,2016,38(06):615-619+730.DOI:10.16050/j.cnki.issn1674-6309.2016.06.003." "陈香君,刘二强,回丽媛: CHEN Xiangjun LIU Erqiang HUI Liyuan ZHU Mingxing WANG Xiuqing " "新型抗肿瘤杂合抗菌肽的设计、合成及抗肿瘤活性研究:Design, Synthesis and Antitumor Research of New Antitumor Hybrid Antimicrobial Peptides" "DRAMP37316" "GIGTKILGGGRIPACIA" "17" "MH" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Alpha helix" "Not found" "Not found" "Comment: Based on LL-37 or HNP-1 in the human body, according to the above-mentioned relevant parameter analysis, the active fragment of LL-37 is the amino acid sequence 10-17 and the active fragment of HNP-1 is the amino acid sequence 5-11, which is similar to Maximin. The active amino acid sequence fragments 1-8 and 11-17 of 1 and the active amino acid sequence fragments 1-9 of Dermaseptin-B2 are spliced ​​together through "-Glycine (Gly, G) Glycine (Gly, G) -", and the color The amino acid (Trp, W) is replaced with leucine (Leu, L) to increase the net charge of the peptide and synthesize a new hybrid peptide." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16050/j.cnki.issn1674-6309.2016.06.003. " "[J].宁夏医科大学学报,2016,38(06):615-619+730.DOI:10.16050/j.cnki.issn1674-6309.2016.06.003." "陈香君,刘二强,回丽媛: CHEN Xiangjun LIU Erqiang HUI Liyuan ZHU Mingxing WANG Xiuqing " "新型抗肿瘤杂合抗菌肽的设计、合成及抗肿瘤活性研究:Design, Synthesis and Antitumor Research of New Antitumor Hybrid Antimicrobial Peptides" "DRAMP37317" "KEKIGKEFGGRIPACIA" "17" "LP" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Alpha helix" "Not found" "Not found" "Comment: Based on LL-37 or HNP-1 in the human body, according to the above-mentioned relevant parameter analysis, the active fragment of LL-37 is the amino acid sequence 10-17 and the active fragment of HNP-1 is the amino acid sequence 5-11, which is similar to Maximin. The active amino acid sequence fragments 1-8 and 11-17 of 1 and the active amino acid sequence fragments 1-9 of Dermaseptin-B2 are spliced ​​together through "-Glycine (Gly, G) Glycine (Gly, G) -", and the color The amino acid (Trp, W) is replaced with leucine (Leu, L) to increase the net charge of the peptide and synthesize a new hybrid peptide." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16050/j.cnki.issn1674-6309.2016.06.003. " "[J].宁夏医科大学学报,2016,38(06):615-619+730.DOI:10.16050/j.cnki.issn1674-6309.2016.06.003." "陈香君,刘二强,回丽媛: CHEN Xiangjun LIU Erqiang HUI Liyuan ZHU Mingxing WANG Xiuqing " "新型抗肿瘤杂合抗菌肽的设计、合成及抗肿瘤活性研究:Design, Synthesis and Antitumor Research of New Antitumor Hybrid Antimicrobial Peptides" "DRAMP37318" "KEKIGKEFGGKTALKGA" "17" "LM" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Alpha helix" "Not found" "Not found" "Comment: Based on LL-37 or HNP-1 in the human body, according to the above-mentioned relevant parameter analysis, the active fragment of LL-37 is the amino acid sequence 10-17 and the active fragment of HNP-1 is the amino acid sequence 5-11, which is similar to Maximin. The active amino acid sequence fragments 1-8 and 11-17 of 1 and the active amino acid sequence fragments 1-9 of Dermaseptin-B2 are spliced ​​together through "-Glycine (Gly, G) Glycine (Gly, G) -", and the color The amino acid (Trp, W) is replaced with leucine (Leu, L) to increase the net charge of the peptide and synthesize a new hybrid peptide." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16050/j.cnki.issn1674-6309.2016.06.003. " "[J].宁夏医科大学学报,2016,38(06):615-619+730.DOI:10.16050/j.cnki.issn1674-6309.2016.06.003." "陈香君,刘二强,回丽媛: CHEN Xiangjun LIU Erqiang HUI Liyuan ZHU Mingxing WANG Xiuqing " "新型抗肿瘤杂合抗菌肽的设计、合成及抗肿瘤活性研究:Design, Synthesis and Antitumor Research of New Antitumor Hybrid Antimicrobial Peptides" "DRAMP37319" "WWWLRKIW" "8" "Temporin-SHf" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: A novel antimicrobial peptide Temporin-SHf was designed by means of genetic engineering using Pichia Pastoris codon preference." "Gram-positive bacteria: Staphylococcus aureus ##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13995/j.cnki.11-1802/ts.023811. " "[J].食品与发酵工业2020,46(14),98-102 DOI:10.13995/j.cnki.11-1802/ts.023811" "王莲哲,江宏浩,唐宜飞,洪军:WANG Lianzhe JIANG Honghao TANG Yifei HONG Jun " "新型抗菌肽Temporin-SHf在毕赤酵母中的表达及诱导条件优化:Expression of novel antibacterial peptide Temporin-SHf in Pichia pastoris and optimization of induction conditions" "DRAMP37320" "AFALIAGALYRIFHRR" "16" "LHH1" "No entry found" "Not found" "Not found" "Homo sapiens (Human)" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: Has good antibacterial and antitumor activity. The antimicrobial peptide has very low toxicity to mammalian cells and has high development and application value." "Gram-positive bacteria: Staphylococcus aureus ATCC 29213 (MIC=4μg/mL), Listeria monocytogenes ATCC 7611 (MIC=8μg/mL), Lactobacillus casei HZ1(MIC>256μg/mL)##Gram-negative bacteria: Klebsiella pneumoniae ATCC 700603 (MIC>256μg/mL), Enterobacter aerogenes ATCC 13048 (MIC>256μg/mL)##Fungus: Saccharomyces cerevisiae(MIC=64μg/mL), Pichia pastoris GS115(MIC=32μg/mL)." "HD50 = 200μmol/L against on Goat red blood cells." "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13684/j.cnki.spkj.2020.08.002. " "[J].食品科技,2020,45(08):1-7.DOI:10.13684/j.cnki.spkj.2020.08.002." "贺军芳,金杜欣,罗学刚:HE Junfang JIN Duxin LUO Xuegang ZHANG Tongcun " "新型抗菌肽LHH1的重组表达及对肠道微生态的影响:Expression of Novel Antimicrobial Peptide LHH1 and Its Influence on Intestinal Flora" "DRAMP37321" "LLRHVVKILEKYL" "13" "T-La(Temporin-La)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Not found" "10.13200/j.cnki.cjb.002626. " "[J].中国生物制品学杂志,2019,32(09):987-992.DOI:10.13200/j.cnki.cjb.002626." "张秋利,刘梦月,姜轩: ZHANG Qiu-li LIU Meng-yue JIANG Xuan JIN Tian-ming ZHAO Rui-li MA Ji-fei FU Chao SHANG Zi-yu " "新抗菌肽RGD-嵌合体靶向抗黑色素瘤活性:Antitumor activity of a novel antibacterial peptide RGD-chimera targeting melanoma" "DRAMP37322" "FLRHVVKILSKYL" "13" "T-La(FS) (Derived from T-La)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: The static charge number of polypeptide was increased by changing individual amino acid types to increase its anti-tumor biological activity" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Not found" "10.13200/j.cnki.cjb.002626. " "[J].中国生物制品学杂志,2019,32(09):987-992.DOI:10.13200/j.cnki.cjb.002626." "张秋利,刘梦月,姜轩: ZHANG Qiu-li LIU Meng-yue JIANG Xuan JIN Tian-ming ZHAO Rui-li MA Ji-fei FU Chao SHANG Zi-yu " "新抗菌肽RGD-嵌合体靶向抗黑色素瘤活性:Antitumor activity of a novel antibacterial peptide RGD-chimera targeting melanoma" "DRAMP37323" "INLKALAALAKKILPGLLKRIKTLL" "25" "IG-1(melittin Anoplin as the C-terminal and melittin Mastoparan as the N-terminal, connected through Pro)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: melittin Anoplin as the C-terminal and melittin Mastoparan as the N-terminal, connected through Pro" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "DOI:10.19286/j.cnki.cci.2018.12.037. " "[J].煤炭与化工,2018,41(12):120-122.DOI:10.19286/j.cnki.cci.2018.12.037." "刘立伟,崔福轩,韩晓岩: Liu Liwei Cui Fuxuan Han Xiaoyan " "肽链的N,C末端对抗菌肽活性的影响研究;Effects of peptide N and C terminal on the activity of antimicrobial peptide" "DRAMP37324" "GILKKFMLHRGTKVYKMRTLSKRSH" "25" "Scolopin-2 (S-2)" "No entry found" "Not found" "Not found" "Scolopendra subspinipes mutilans" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus (MIC=18μmol/L), Bacillus subtilis(MIC=24μmol/L)##Gram-negative bacteria: Escherichia coli(K2Ds1) (MIC=12μmol/L), Salmonella (MIC=16μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane, DNA" "10.13560/j.cnki.biotech.bull.1985.2018-0476. " "[J].生物技术通报,2018,34(11):179-190.DOI:10.13560/j.cnki.biotech.bull.1985.2018-0476." "卢佳,邓秋萍,任文华: LU Jia DENG Qiu-ping REN Wen-hua " "少棘蜈蚣抗菌肽Scolopin 2-NH2的抗菌作用机制研究:Mechanism of Antimicrobial Peptide Scolopin 2-NH2 Isolated from Scolopendra subspinipes mutilans" "DRAMP37325" "HFLKKLVKLAKKIL" "14" "[G4、T5、N8K]Temporin-1Dra" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Alpha helix( 6 residues)" "The secondary structure consisted of α-helix (6 amino acid residues), accounting for 42.86%; Extended chain (2 amino acid residues involved), accounting for 14.29%; Random curling (6 amino acid residues involved) accounted for 42.86%." "Not found" "Comment: Has inhibitory effect on drug-resistant strains of Candida albicans, low hemolytic in vitro and obvious bactericidal effect" "Fungus: Canidia albicans ATCC 98001(MIC=64μg/mL), Canidia albicans resistant 1、2、4、8(MIC=128μg/mL), Canidia albicans 3、5、6、7、9、10(MIC=64μg/mL),FLC-resistant Canidia albicans(MIC=128μg/mL)." "The hemolysis rate was less than 5% in the range of 128μg·mL-1(MIC). 1% Triton X-100 were used as the positive control." "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13664/j.cnki.pcr.2020.04.003. " "[J].药学与临床研究,2020,28(04):251-254.DOI:10.13664/j.cnki.pcr.2020.04.003." "练家惠,陈向东,汪辉: LIAN Jiahui CHEN Xiangdong WANG Hui CHEN Quanshun " "人工合成抗菌肽生物信息学分析及其抑菌活性研究:Bioinformatics and Antimicrobial Activity of a Remoulded Antimicrobial Peptide" "DRAMP37326" "FFKRLLKSVRRAVKKF" "16" "Hc-16(Derived from Hc-CATH)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal" "Not found" "Amphipathic alpha helix structure" "Not found" "Not found" "Comment: The Hc-CATH amphiphilic α helix region was intercepted and a series of modifications were obtained by deleting N-terminal and C-terminal one by one." "Gram-positive bacteria: Staphylococcus aureus (CI) (MIC=18.8μg/mL)##Gram-negative bacteria: Escherichia coli 1 (CIb) (MIC=75μg/mL), Shigella dysenteriae(CI) (MIC=37.5μg/mL), Proteus mirabilis (CI) (MIC=150μg/mL), Pseudomonas aeruginosa 1 (CI) (MIC=4.69μg/mL), Salmonella paratyphi A (CI) (MIC=37.5μg/mL);##Fungus: Candida albicans(CI) (MIC=150μg/mL), Candida glabrata 2 (CI) (MIC=37.5μg/mL), Arcyria cinerea (CI) (MIC=150μg/mL)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13345/j.cjb.200583. " "[J].生物工程学报,2021,37(07):2534-2542.DOI:10.13345/j.cjb.200583." "高久香,王义鹏,于海宁: Jiuxiang Gao Yipeng Wang Haining Yu " "青环海蛇抗菌肽Hc-CATH的分子设计及药效毒理优化;Molecular design, pharmacology and toxicology optimization of antimicrobial peptide from Hydrophis cyanocinctus, Hc-CATH" "DRAMP37327" "NE" "2" "PG-YGT-T2" "No entry found" "Not found" "Not found" "Taraxacum mongolicum" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: This research is helpful for the development and utilization of Taraxacum mongolicum protein peptides and the production of new Taraxacum mongolicum antimicrobial peptides." "Gram-positive bacteria: Staphylococcus aureus##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13271/j.mpb.018.003388. " "[J].分子植物育种,2020,18(10):3388-3394.DOI:10.13271/j.mpb.018.003388." "林贺,金平,杨培国:Lin He Jin Ping Yang Peiguo Tang Shan Zhang Hui Yin Chunmei " "蒲公英酶解抗菌肽的分析:Analysis of Antimicrobial Peptides in Taraxacum mongolicum Enzymatic Hydrolysis" "DRAMP37328" "KLLSHSLLVTLA" "12" "JH-0" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Random coil" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2017.01.008. " "[J].中国畜牧兽医,2017,44(01):59-64.DOI:10.16431/j.cnki.1671-7236.2017.01.008." "李杰,杭柏林,秦爱建: LI Jie HANG Bo-lin QIN Ai-jian QIAN Kun HU Jian-he " "牛血红蛋白源抗菌肽P3及其类似肽的生物信息学分析:Bioinformatics Analysis of Antimicrobial Peptide P3 from Bovine Hemoglobin and Its Analogs" "DRAMP37329" "GWGSFFKKAAHVGKHVGKAALTHYL" "25" "Pleurocidin" "No entry found" "Not found" "Not found" "Pseudopleuronectes americanu" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Bacillus subtilis BS168 (MIC=150μg/mL)##Gram-negative bacteria: Escherichia coli DH5α (MIC=300μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13345/j.cjb.150286. " "[J].生物工程学报,2016,32(03):365-374.DOI:10.13345/j.cjb.150286." "徐雪姣,查向东,车媛媛:Xuejiao Xu Xiangdong Zha Yuanyuan Che Lijuan Ma Siqun Wu Peilong Yang Huoqing Huang Bin Yao " "美洲拟鲽抗菌肽Pleurocidin在大肠杆菌中的高效分泌表达及优化:Expression of Pleurocidin from winter flounder in Escherichia coli and optimization of culture conditions" "DRAMP37330" "GLESINFQ" "8" "C3(Enzymolysis component 3 obtained frpm enzymolysis of Ovalbumin)" "No entry found" "Not found" "Not found" "Ovalbumin" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: In this study, the crude enzymolysis with antibacterial activity was prepared by enzymolysis of egg albumin. The B3 component with strong antibacterial activity was obtained by ultrafiltration and gel chromatography, and then purified by reversed-phase high performance liquid chromatography (RP-HPLC). The purified B3 component was obtained, among which C3 component had the strongest antibacterial activity." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13652/j.issn.1003-5788.2019.07.001. " "[J].食品与机械,2019,35(07):1-6+86.DOI:10.13652/j.issn.1003-5788.2019.07.001." "蒋雨晴,迟玉杰: JIANG Yu-qing Chi Yu-jie " "卵白蛋白源抗菌肽的分离纯化与结构鉴定:Isolation, purification and identification of antimicrobial peptides from ovalbumin" "DRAMP37331" "FKRIVQRIKDFLRNLVPRTES" "21" "LL-21" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=1mg/mL), Streptococcus pneumoniae (MIC=0.25mg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19526/j.cnki.1005-8915.2014.02.013. " "[J].药物生物技术,2014,21(02):144-148.DOI:10.19526/j.cnki.1005-8915.2014.02.013." "李崇阳,陈梅梅,张小琴:LI Chong-yang CHEN Mei-mei ZHANG Xiao-qin " "两种抗菌肽的体内外抗菌功能研究;In vitro and In vivo Antimicrobial Functions of Two Antimicrobial Peptides" "DRAMP37332" "SKEKIGKEFKRIVQRIKDFLRNLVPRTES" "29" "LL-29" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=2mg/mL), Streptococcus pneumoniae (MIC=0.25mg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19526/j.cnki.1005-8915.2014.02.013. " "[J].药物生物技术,2014,21(02):144-148.DOI:10.19526/j.cnki.1005-8915.2014.02.013." "李崇阳,陈梅梅,张小琴:LI Chong-yang CHEN Mei-mei ZHANG Xiao-qin " "两种抗菌肽的体内外抗菌功能研究;In vitro and In vivo Antimicrobial Functions of Two Antimicrobial Peptides" "DRAMP37333" "DGRCLLIIKLAKLAKKLAKLAK" "22" "CDAK" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13753/j.issn.1007-6611.2017.11.013. " "[J].山西医科大学学报,2017,48(11):1149-1153.DOI:10.13753/j.issn.1007-6611.2017.11.013." "侯磊,岳晨莉,何莉:HOU Lei YUE Chenli HE Li JIA Hui BAI Jun " "连接链对包含CisoDGRC结构抗菌肽诱导乳腺癌细胞凋亡的影响:Effect of connection chain on apoptosis induced by antibacterial peptide containing CisoDGRC in breast cancer cells" "DRAMP37334" "GSSEKPQQELEACQNVCRMKRWSTEMVHRCEKKCEEKFERQQR" "43" "FtAMP-E12A(Derived from FtAMP)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Fungus: F. oxysporum (MIC=16μmol/L), R. chinonsis(MIC=8μmol/L), T.koningii(MIC=6μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13865/j.cnki.cjbmb.2019.02.11. " "[J].中国生物化学与分子生物学报,2019,35(02):196-204.DOI:10.13865/j.cnki.cjbmb.2019.02.11." "崔晓东,王婷芬,杜晶晶:CUI Xiao-Dong WANG Ting-Fen DU Jing-Jing WANG Zhuan-Hua " "苦荞α-螺旋发夹抗菌肽的分子改造抑制植物真菌活性;Molecular Modification and Antifungal Activities of α-Helix Hairpins in Antimicrobial Peptides from Tartary Buckwheat" "DRAMP37335" "GSSEKPQQALEACQNVCRMKRWSEEMVHRCEKKCEEKFERQQR" "43" "FtAMP-E12A/E9K/T24E(Derived from FtAMP)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Fungus: F. oxysporum (MIC=8μmol/L), R. chinonsis(MIC=4μmol/L), T.koningii(MIC=4μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13865/j.cnki.cjbmb.2019.02.11. " "[J].中国生物化学与分子生物学报,2019,35(02):196-204.DOI:10.13865/j.cnki.cjbmb.2019.02.11." "崔晓东,王婷芬,杜晶晶:CUI Xiao-Dong WANG Ting-Fen DU Jing-Jing WANG Zhuan-Hua " "苦荞α-螺旋发夹抗菌肽的分子改造抑制植物真菌活性:Molecular Modification and Antifungal Activities of α-Helix Hairpins in Antimicrobial Peptides from Tartary Buckwheat" "DRAMP37336" "TEMVHRCEKKCEE" "13" "FtAMP-C(Derived from FtAMP)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: According to homology comparison, the spatial structure of FtAMP is a hairpin structure composed of two α-helices fixed by disulfide bonds. At the same time, the structure was predicted and confirmed by experiments. This polypeptide is an antibacterial peptide with trypsin inhibitory activity. , belongs to α-hairpinins inhibitors.FtAMP has a strong inhibitory effect on trypsin, but inhibiting its active site does not affect its antibacterial activity.These results suggest that the antifungal activity of FtAMP may be related to its α-helical structure." "Fungus: Aspergillus niger" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13865/j.cnki.cjbmb.2019.02.11. " "[J].中国生物化学与分子生物学报,2019,35(02):196-204.DOI:10.13865/j.cnki.cjbmb.2019.02.11." "崔晓东,王婷芬,杜晶晶:CUI Xiao-Dong WANG Ting-Fen DU Jing-Jing WANG Zhuan-Hua " "苦荞α-螺旋发夹抗菌肽的分子改造抑制植物真菌活性:Molecular Modification and Antifungal Activities of α-Helix Hairpins in Antimicrobial Peptides from Tartary Buckwheat" "DRAMP37337" "GSSEKPQQALEACQNVCRMKRWSTEMVHRCEKKCEEKFERQQR" "43" "FtAMP-E12A/E9A(Derived from FtAMP)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Fungus: F. oxysporum (MIC=8μmol/L), R. chinonsis(MIC=4μmol/L), T.koningii(MIC=4μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13865/j.cnki.cjbmb.2019.02.11. " "[J].中国生物化学与分子生物学报,2019,35(02):196-204.DOI:10.13865/j.cnki.cjbmb.2019.02.11." "崔晓东,王婷芬,杜晶晶:CUI Xiao-Dong WANG Ting-Fen DU Jing-Jing WANG Zhuan-Hua " "苦荞α-螺旋发夹抗菌肽的分子改造抑制植物真菌活性;Molecular Modification and Antifungal Activities of α-Helix Hairpins in Antimicrobial Peptides from Tartary Buckwheat" "DRAMP37338" "GSSEKPQQELEECQNVCRMKRWSTEMVHRCEKKCEEKFERQQR" "43" "FtAMP" "No entry found" "Not found" "Not found" "Fagopyrum esculentum Moench" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Fungus: F. oxysporum (MIC=16μmol/L), R. chinonsis(MIC=8μmol/L), T.koningii(MIC=8μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13865/j.cnki.cjbmb.2019.02.11. " "[J].中国生物化学与分子生物学报,2019,35(02):196-204.DOI:10.13865/j.cnki.cjbmb.2019.02.11." "崔晓东,王婷芬,杜晶晶:CUI Xiao-Dong WANG Ting-Fen DU Jing-Jing WANG Zhuan-Hua " "苦荞α-螺旋发夹抗菌肽的分子改造抑制植物真菌活性:Molecular Modification and Antifungal Activities of α-Helix Hairpins in Antimicrobial Peptides from Tartary Buckwheat" "DRAMP37339" "PYIPQPRPPHPRL" "13" "B3" "No entry found" "Not found" "Not found" "Bacillus subtilis B3" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Escherichia coli, Salmonella enterica subsp.enterica" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13995/j.cnki.11-1802/ts.016032. " "[J].食品与发酵工业,2018,44(08):78-85.DOI:10.13995/j.cnki.11-1802/ts.016032." "白杰,贠建民,祝发明: BAI Jie YUN Jian-Min ZHU Fa-Ming YAN Hai-Jiao ZHANG Wen-wei AI Dui-yuan " "枯草芽孢杆菌菌株B3抗菌肽的分离纯化与鉴定:Isolation, purification and identification of antibacterial peptide from Bacillus subtilis strain B3" "DRAMP37340" "KKVVFWVKFK" "10" "KSL-W" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Fusobacterium nucleatum 10953(MIC=0.0156mg/mL), Porphyromonas gingivalis 33277(MIC=0.125mg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13381/j.cnki.cjm.201407004. " "[J].中国微生态学杂志,2014,26(07):760-763.DOI:10.13381/j.cnki.cjm.201407004." "李冀寅,那荣威,王一宇: LI Ji-yin NA Rong-wei WANG Yi-yu SUI Fu-yong MA Guo-wu LIU Hui-ying " "抗菌肽对种植体周围炎主要致病菌生长抑制作用的研究:Inhibitory effect of antimicrobial peptides on peri-implantitis pathogens in vitro" "DRAMP37341" "IPLRGAFINGRWDSQCHRFSNGAIACA" "27" "urumin" "No entry found" "Not found" "Not found" "Hydrophylax bahuvistara" "Antimicrobial, Antiviral" "Not found" "Random coil" "Not found" "Not found" "Comment: The urumin structure is dominated by random curling, and the binding of multiple residues on HA can be stabilized. The variable structure of Urumin may not be conducive to further application and development, suggesting that full consideration should be given to improving the stability of polypeptide and further enhancing the binding force of polypeptide and HA when reforming urumin." "Virus: Influenza A virus (H1N1)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16438/j.0513-4870.2021-0483. " "[J].药学学报,2021,56(09):2553-2560.DOI:10.16438/j.0513-4870.2021-0483." "李红梅,郑伟娟,李家璜: LI Hong-mei ZHENG Wei-juan LI Jia-huang HUA Zi-chun " "抗菌肽urumin与甲型流感病毒H1N1 HA蛋白的相互作用研究:Interaction study of the antibacterial peptide urumin with the H1N1 HA protein of influenza A virus" "DRAMP37342" "HHHHHHGMLKRVWK RVFKLLKRYWRQLKKPVR" "33" "SAAP-148(Derived from LL-37)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+" "Not found" "Not found" "Not found" "Not found" "Comment: Derivatives produced by a series of random substitution optimization based on the structure of the antibacterial peptide LL-37 in the human body" "Gram-positive bacteria:Enterococcus faecalis, Bacillus melanogaster" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16380/j.kcxb.2023.06.002. " "[J].昆虫学报,2023,66(06):736-746." "王珏,沈东旭,彭云武: WANG Jue SHEN Dong-Xu PENG Yun-Wu QIAN He-Ying ZHAO Qiao-Ling CHEN An-Li " "抗菌肽SAAP-148对家蚕细菌性肠道病病原细菌的抗性分析:Resistance analysis of the antimicrobial peptide SAAP-148 against the pathogenic bacteria of bacterial intestinal disease in Bombyx mori" "DRAMP37343" "RIKLRIKLLRLLRL" "14" "RIKL(Designed by molecular dynamics simulation)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix structure in simulated hydrophobic environment" "RIKL presents an irregular curly structure in PBS. In 50%TFE solution, the spectral signature of RIKL shows two negative peaks near both about 207 nm and 226 nm, which proves that RIKL forms an α-helix structure in a simulated hydrophobic environment" "Not found" "Comment: The antimicrobial peptide RIKL was designed using (RXKY)2(YRY)2 (X for Ile,Y for Leu) as the template" "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=4μmol/L), Staphylococcus aureus ATCC 25923(MIC=8μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=4μmol/L), Bacillus subtilis CMCC 63501(MIC=8μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=2μmol/L), Escherichia coli UB1005(MIC=2μmol/L),Escherichia coli K88(MIC=2μmol/L), Salmonella typhimurium ATCC 14028(MIC=2μmol/L),Salmonella pullorum C79–13(MIC=2μmol/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13345/j.cjb.210219. " "[J].生物工程学报,2022,38(01):174-184.DOI:10.13345/j.cjb.210219." "方禹鑫,李玲,付文华: FANG Yuxin LI Ling FU Wenhua DONG Na SHAN Anshan " "抗菌肽RIKL的分子设计及生物学活性分析:Molecular design and biological activity analysis of antimicrobial peptide RIKL" "DRAMP37344" "GFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY" "40" "Plectasin" "No entry found" "Not found" "Not found" "Pseudoplectania nigrella" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Plectasin has a strong affinity with LipidⅡ, the precursor substance for bacterial cell membrane formation, and can prevent the formation of bacterial cell membranes by binding to LipidⅡ, thus preventing the reproduction of bacterial cells.Plectasin's unique mechanism of action is less likely to induce drug-resistant strains." "Gram-positive bacteria: Streptococcus pneumoniae." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19526/j.cnki.1005-8915.2014.05.010. " "[J].药物生物技术,2014,21(05):424-428.DOI:10.19526/j.cnki.1005-8915.2014.05.010." "温耀安,朱哲,石羽: WEN Yao-an ZHU Zhe SHI Yu GUO Song-wen LI Ling CHEN Xin " "抗菌肽Plectasin原核表达条件的正交试验优化研究:Research on Optimization Expression Conditions of Plectasin Prokaryotic Expressions by the Orthogonal Experiment" "DRAMP37345" "KKFKETADKLIESAKQQLESLAKEMK" "26" "MAF-1A(Musca domesticaantifungal peptide-1A)" "No entry found" "Not found" "Not found" "musca domestictica" "Antimicrobial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: The derived peptide MAF-1A22S3 has obvious antifungal effect in vitro" "Fungus:Candida albican ATCC10231 (MIC=625.00 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19367/j.cnki.2096-8388.2023.01.004. " "[J].贵州医科大学学报,2023,48(01):25-32.DOI:10.19367/j.cnki.2096-8388.2023.01.004." "黄敏慧,曾晔,张迎春:HUANG Minhui ZENG Ye ZHANG Yingchun LI Caiduo WU Jianwei CHEN Zhenghong WANG Tao " "抗菌肽MAF-1A洐生肽的设计及其抗白色念珠菌活性:Design of antibacterial peptide MAF-1A derivatives and their activity against Candida albicans" "DRAMP37346" "KKTAKKLIKSAKIWLIKWAK" "20" "MAF-1A20S3(Derived from MAF-1A)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: The derived peptide MAF-1A22S5 has obvious antifungal effect in vitro" "Fungus:Candida albican ATCC10231 (MIC=125.00 µM)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19367/j.cnki.2096-8388.2023.01.004. " "[J].贵州医科大学学报,2023,48(01):25-32.DOI:10.19367/j.cnki.2096-8388.2023.01.004." "黄敏慧,曾晔,张迎春:HUANG Minhui ZENG Ye ZHANG Yingchun LI Caiduo WU Jianwei CHEN Zhenghong WANG Tao " "抗菌肽MAF-1A洐生肽的设计及其抗白色念珠菌活性:Design of antibacterial peptide MAF-2A derivatives and their activity against Candida albicans" "DRAMP37347" "GLLKSLCKKFVK" "12" "Lc-NKlysin-1a" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Scavenging effect on DPPH free radicals and hydroxyl free radicals." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13684/j.cnki.spkj.2018.10.002. " "[J].食品科技,2018,43(10):8-14.DOI:10.13684/j.cnki.spkj.2018.10.002." "罗文杰,钟亨任,唐梨纯: LUO Wen-jie ZHONG Heng-ren TANG Li-chun SONG Yan-ting Manchu Riga ZHANG Ying-xia " "抗菌肽Lc-NKlysin-1a抗氧化活性及其稳定性:The antioxidant activity and stability of antimicrobial peptide Lc-NKlysin-1a" "DRAMP37348" "RGGLCYCRGRFCVCVGR" "17" "IB-367" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ##Gram-negative bacteria: Escherichia coli." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.15952/j.cnki.cjsc.1005-1511.2016.07.16116. " "[J].合成化学,2016,24(07):600-603.DOI:10.15952/j.cnki.cjsc.1005-1511.2016.07.16116." "王小青,高杨,尹志峰: WANG Xiao-qing GAO Yang YIN Zhi-feng GONG Wen-jing ZHAO Hong-ling WANG Liang-you " "抗菌肽IB-367的固相合成与抑菌活性:Solid Phase Synthesis and Anti-microbial Activities of the Antibacterial Peptide IB-367" "DRAMP37349" "VQWRAIRVRVIR" "12" "DJK-5" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: DJK-5 is based on the sequence of synthetic peptide 1018, and its antibacterial mechanism is similar to that of 1018. They both exert bactericidal effects by degrading the second messenger nucleotides guanosine pentaphosphate and guanosine tetraphosphate [(p)ppGpp]." "Gram-positive bacteria: Staphylococcus aureus ##Gram-negative bacteria: Pseudomonas aeruginosa " "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13819/j.issn.2096-708X.2023.01.023. " "[J].湖北医药学院学报,2023,42(01):107-110.DOI:10.13819/j.issn.2096-708X.2023.01.023." "洪锋,段沁颜,程俊翔" "抗菌肽DJK-5在口腔细菌生物膜中应用的研究进展" "DRAMP37350" "GWLKKIGKKIERVGQNTRDATIQAIGVAQQAANVAATLKGK" "41" "Cec4" "No entry found" "Not found" "Not found" "Musca domestica" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Truncation causes Cec4 to lose its antibacterial activity. The antibacterial activity of Cec4-4 after amino acid substitution is twice as high as that of the parent peptide against each test bacteria. The antibacterial peptide has no hemolytic reaction in the human body at a concentration of 1 mg/mL." "Gram-negative bacteria: Acinetobacter baumannii, Klebsiella pneumoniae." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16519/j.cnki.1004-311x.2019.04.0056. " "[J].生物技术,2019,29(04):330-335.DOI:10.16519/j.cnki.1004-311x.2019.04.0056." "彭建,赵行行,吴兆颖: PENG Jian ZHAO Xing-xing WU Zhao-ying WANG Tao SHANG Xiao-li GUO Guo " "抗菌肽Cec4的结构改造及抗菌活性研究:Structural modification and antibacterial related activity study of antimicrobial peptide Cec4" "DRAMP37351" "GWLKKIGKKIERVGQNTRDATIQAIGVAQQAANVAAFLKGK" "41" "Cec4-4(Cec4 amino acid replacement peptide)" "No entry found" "Not found" "Not found" "Musca domestica" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Truncation causes Cec4 to lose its antibacterial activity. The antibacterial activity of Cec4-4 after amino acid substitution is twice as high as that of the parent peptide against each test bacteria. The antibacterial peptide has no hemolytic reaction in the human body at a concentration of 1 mg/mL." "Gram-negative bacteria: Acinetobacter baumannii, Klebsiella pneumoniae." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16519/j.cnki.1004-311x.2019.04.0056. " "[J].生物技术,2019,29(04):330-335.DOI:10.16519/j.cnki.1004-311x.2019.04.0056." "彭建,赵行行,吴兆颖: PENG Jian ZHAO Xing-xing WU Zhao-ying WANG Tao SHANG Xiao-li GUO Guo " "抗菌肽Cec4的结构改造及抗菌活性研究:Structural modification and antibacterial related activity study of antimicrobial peptide Cec5" "DRAMP37352" "GWLKKIGKKIERVGQNTRDATIQAIGVAQQAANVAAFLKGK" "41" "Cec4a(Mutant of Cec4)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-negative bacteria: Acinetobacter baumannii ATCC 19606(MIC=4μg/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13523/j.cb.2105046." "[J].中国生物工程杂志,2021,41(10):12-18.DOI:10.13523/j.cb.2105046." "陈素芳,夏明印,曾丽艳:CHEN Su-fang XIA Ming-yin ZENG Li-yan AN Xiao-qin TIAN Min-fang PENG Jian " "抗菌肽Cec4a的重组表达和抗菌活性研究;Recombinant Expression and Detection of Antimicrobial Activity of Cec4a" "DRAMP37353" "FRPPIRRPPIRPPFYPPFRPPIRPPIFPPIRPPFRPP" "37" "BSN-37(Truncated peptide of bovine cathelicidin antimicrobial peptide Bac5)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Antimicrobial peptide BSN-37 is a truncated peptide of bovine cathelicidin antimicrobial peptide Bac5" "Gram-positive bacteria: Bacillus subtillis CMCC 63501 (MIC=12.5μg/mL)##Gram-negative bacteria: Escherichia coli CMCC44103 (MIC=6.25μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2019.01.034. " "[J].中国畜牧兽医,2019,46(01):287-295.DOI:10.16431/j.cnki.1671-7236.2019.01.034." "张炜,杭柏林,司素锦: ZHANG Wei HANG Bolin SI Sujin NING Chunmei LI Jie HU Jianhe " "抗菌肽BSN-37的抑菌活性及其稳定性分析:Bacteriostatic Activity and Stability Analysis of Antimicrobial Peptide BSN-37" "DRAMP37354" "GVTFNALKGVAKTVAAQLLKTAR" "23" "Brevinin-GR23" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus " "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane, DNA" "10.15886/j.cnki.hdxbzkb.2018.0050. " "[J].海南大学学报(自然科学版),2018,36(04):360-367.DOI:10.15886/j.cnki.hdxbzkb.2018.0050." "钟亨任,谢志鹏,魏涵淇:Zhong Hengren Xie Zhipeng Wei Hanqi Zhang Shuxia He Peilan Song Yanting Zhang Yingxia " "抗菌肽Brevinin-GR23抗金黄色葡萄球菌作用机制的初步研究:Mechanism of Brevinin-GR23 against Staphylococcus aureus" "DRAMP37355" "RRWQWR" "6" "BLFcin6" "No entry found" "Not found" "Not found" "Bovine lactoferricin" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: Compared with BLFcin or BLF, BLFcin6 exhibits similar and stronger antibacterial activity, but loses its anticancer activity." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16476/j.pibb.2017.0256. " "[J].生物化学与生物物理进展,2018,45(03):351-362.DOI:10.16476/j.pibb.2017.0256." "孔真真,赵立岭,唐艳: KONG Zhen-Zhen ZHAO Li-Ling TANG Yan WANG Ji-Hua CAO Zan-Xia " "抗菌肽BLFcin6与不同磷脂膜之间相互作用的分子动力学模拟研究:Study on The Interaction Between BLFcin6 and Different Phospholipid Membrane by Molecular Dynamics Simulation" "DRAMP37356" "KFFRKLKKSVKKRAKEFFKKPRVIGVSIPF" "30" "BF-30" "No entry found" "Not found" "Not found" "Bungarus fasciatus" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=4μg/mL), Staphylococcus aureus Clinical strains(MIC=16μg/mL)##Gram-negative bacteria: Pseudomonas aeruginosa ATCC 27853(MIC=2μg/mL), Pseudomonas aeruginosa Clinical strains(MIC=16μg/mL), Pseudomonas aeruginosa PAO1(MIC=8μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19526/j.cnki.1005-8915.2015.01.004. " "[J].药物生物技术,2015,22(01):14-19.DOI:10.19526/j.cnki.1005-8915.2015.01.004." "李博,李冰,田玉伟: LI Bo LI Bing TIAN Yu-wei WANG Yan-rong DOU Jie WANG Hui ZHOU Chang-lin " "抗菌肽BF-30体外抗耐药细菌生物被膜的研究:The Anti-Biofilm Activity against Drug-Resistance Bacterial of Antimicrobial Peptide BF-30 in vitro" "DRAMP37357" "KTISFILK" "8" "FAH34" "No entry found" "Not found" "Not found" "Larimichthys crocea" "Antimicrobial, Antibacterial, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Function: FAH34 is a new type of antimicrobial peptide with thermal stability to Vibrio haemolyticus, which can be used as a biological preservative in aquatic pickled food." "Gram-negative bacteria: Vibrio parahaemolyticus(MIC=7.80 µM)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane(very possibly)" "10.16429/j.1009-7848.2023.12.026. " "中国食品学报,2023,23(12):247-254." "李若冰, 刘嘉鑫, 金日天, 翁武银, 张志刚, 杨燊: Li Ruobing Liu Jiaxin Jin Ritian Weng Wuyin Zhang Zhigang Yang Shen " "酒糟大黄鱼抗菌肽 FAH34 的抑菌活性及热稳定性:Antibacterial Activity, Mechanism and Thermal Stability of Antibacterial Peptide FAH34 from Distiller's Grains Larimichthys crocea" "DRAMP37358" "DSMDAVKLAKLLIDKMRCKVTKVC" "24" "Jindongenin-1D" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus (MIC=28μg/mL)##Gram-negative bacteria: Escherichia coli 25922 (MIC=16μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.14188/j.ajsh.2017.04.011. " "[J].生物资源,2017,39(04):303-307.DOI:10.14188/j.ajsh.2017.04.011." "陶双燕,邱雨莹,杨黎江: TAO Shuangyan QIU Yuying YANG Lijiang YANG Yexiu LIU Zichao " "景东湍蛙抗菌肽jindongenin-1d的分析和活性测定:Analysis and bioactivities of antimicrobial peptide jindongenin-1d from Amolops jingdongensis" "DRAMP37359" "DSMGAVKLAKLLIDKMKCEVTKAC" "24" "Jindongenin-1" "No entry found" "Not found" "Not found" "Amolops jingdongensis" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.14188/j.ajsh.2017.04.011. " "[J].生物资源,2017,39(04):303-307.DOI:10.14188/j.ajsh.2017.04.011." "陶双燕,邱雨莹,杨黎江: TAO Shuangyan QIU Yuying YANG Lijiang YANG Yexiu LIU Zichao " "景东湍蛙抗菌肽jindongenin-1d的分析和活性测定:Analysis and bioactivities of antimicrobial peptide jindongenin-2d from Amolops jingdongensis" "DRAMP37360" "DSMGALKLAKLLIDKMKCEVTKAC" "24" "Jindongenin-1C" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.14188/j.ajsh.2017.04.011. " "[J].生物资源,2017,39(04):303-307.DOI:10.14188/j.ajsh.2017.04.011." "陶双燕,邱雨莹,杨黎江: TAO Shuangyan QIU Yuying YANG Lijiang YANG Yexiu LIU Zichao " "景东湍蛙抗菌肽jindongenin-1d的分析和活性测定:Analysis and bioactivities of antimicrobial peptide jindongenin-3d from Amolops jingdongensis" "DRAMP37361" "MKKTAIAIAVALAGFARVRQK" "21" "P-RQK" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus ATCC 26003##Gram-negative bacteria: Escherichia coli 44113." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16121/j.cnki.cn45-1347/r.2017.02.03. " "[J].内科,2017,12(02):153-156.DOI:10.16121/j.cnki.cn45-1347/r.2017.02.03." "谭咪乐,李永杰,黄凌凌:TAN Mile LI Yongjie HUANG Lingling LIANG Ningsheng " "将大肠杆菌OmpA信号肽改造成为抗菌肽的研究:Study on conversion of Omp A signal peptide of Escherichia coli to antimicrobial peptide" "DRAMP37362" "EWKLPDLIINHITLTRRNCNKYRCG" "25" "c-Muscin" "No entry found" "Not found" "Not found" "Musca domestica" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Not found" "Not found" "Comment: By analyzing housefly digital gene expression profiling (DGE) and transcriptome data (Tang et al., 2014), this paper found that the expression of an unknown gene increased significantly after bacterial stimulation; analysis of the polypeptide encoded by it found that it has antibacterial properties Typical characteristics of the peptide, and experiments have confirmed that the peptide synthesized from its mature peptide has broad-spectrum antibacterial activity.This gene was first discovered in house flies. Currently, no homologous sequence has been found and it cannot be classified." "Gram-positive bacteria: Microbacterium oxydans(MIC=0.164μmol/L), Bacillus cereus (MIC=0.327μmol/L), Bacillus megaterium(MIC=3.27μmol/L), Micrococcus luteus(MIC=0.164μmol/L), Sporosarcina ureae(MIC=164μmol/L), Staphylococcus aureus(MIC=164μmol/L)##Gram-negative bacteria: Aeromonas hydrophila(MIC=1.64μmol/L), Salmonella gullinarum(MIC=1.64μmol/L), Enterobacter amnigenus(MIC=16.4μmol/L), Escherichia coli ATCC 25922(MIC=16.4μmol/L), Salmonella typhi(MIC=16.4μmol/L), Shigella sp.(MIC=16.4μmol/L), Pseudomonas fluorescens(MIC=32.7μmol/L), Proteus sp.(MIC=16.4μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Cyclic" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16380/j.kcxb.2015.06.005. " "[J].昆虫学报,2015,58(06):617-624.DOI:10.16380/j.kcxb.2015.06.005." "杨雪,唐婷,王一丽:YANG Xue TANG Ting WANG Yi-Li LIU Xin CAO Xin-Ru NI Zhi-Hua LIU Feng-Song " "家蝇新型抗菌肽Muscin的基因克隆、表达模式及抑菌活性:Gene cloning,expression profiling and anti-microbial assay of Muscin,a new antimicrobial peptide in the housefly(Musca domestica)" "DRAMP37363" "FLRALWRVAKRLF" "13" "LP-M2(Derived from Lausporin-1)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Cationic α-helical antimicrobial peptide composed of 15 amino acid residues" "Not found" "Comment: Based on the Lausporin-1 sequence and using basic amino acid substitution method, four derivative peptides LP-M1, LP-M2, LP-M3 and LP-M4 were designed. Compared with the wild type, these peptides have better effects on the studied "ESKAPE" All pathogenic bacteria showed good antibacterial activity (MIC: 5-20 μg/mL), and the hemolytic activity of LP-M3 was significantly reduced." "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=5μmol/L), Staphylococcus aureus ATCC 25923(MIC=5μmol/L), Enterococcus faecalis ATCC 29212(MIC=10μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=5μmol/L, Escherichia coli ATCC 35218(MIC=10μmol/L), Pseudomonas aeruginosa ATCC 27853(MIC=10μmol/L), Klebsiella pneumoniae ATCC 27853(MIC=5μmol/L),acinetobacter baumannii ATCC 19606(MIC=5μmol/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" ":10.13819/j.issn.2096-708X.2021.05.001. " "[J].湖北医药学院学报,2021,40(05):441-445+453.DOI:10.13819/j.issn.2096-708X.2021.05.001." "罗旭东,张凯月,蒋僡雯: LUO Xu-dong ZHANG Kai-yue JIANG Hui-wen LI Fang-yan CHEN Zong-yun " "基于蝎抗菌肽Lausporin-1设计衍生肽以优化其抗“ESKAPE”病原菌活性:Analogues Designed from Scorpion-Derived Peptide Lausporin-1 Exhibit Improved Antimicrobial Activity Against ‘ESKAPE’ Pathogens" "DRAMP37364" "FLSRLWRVAKRLF" "13" "LP-M4(Derived from Lausporin-1)" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Cationic α-helical antimicrobial peptide composed of 17 amino acid residues" "Not found" "Comment: Based on the Lausporin-1 sequence and using basic amino acid substitution method, four derivative peptides LP-M1, LP-M2, LP-M3 and LP-M4 were designed. Compared with the wild type, these peptides have better effects on the studied "ESKAPE" All pathogenic bacteria showed good antibacterial activity (MIC: 5-20 μg/mL), and the hemolytic activity of LP-M3 was significantly reduced." "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=5μmol/L), Staphylococcus aureus ATCC 25923(MIC=10μmol/L), Enterococcus faecalis ATCC 29212(MIC=5μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=5μmol/L, Escherichia coli ATCC 35218(MIC=10μmol/L), Pseudomonas aeruginosa ATCC 27853(MIC=10μmol/L), Klebsiella pneumoniae ATCC 27853(MIC=10μmol/L),acinetobacter baumannii ATCC 19606(MIC=5μmol/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" ":10.13819/j.issn.2096-708X.2021.05.001. " "[J].湖北医药学院学报,2021,40(05):441-445+453.DOI:10.13819/j.issn.2096-708X.2021.05.001." "罗旭东,张凯月,蒋僡雯: LUO Xu-dong ZHANG Kai-yue JIANG Hui-wen LI Fang-yan CHEN Zong-yun " "基于蝎抗菌肽Lausporin-1设计衍生肽以优化其抗“ESKAPE”病原菌活性:Analogues Designed from Scorpion-Derived Peptide Lausporin-2 Exhibit Improved Antimicrobial Activity Against ‘ESKAPE’ Pathogens" "DRAMP37365" "FLSALWGVAKSLF" "13" "Lausporin-1" "No entry found" "Not found" "Not found" "Liocheles australasiae" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Not found" "Cationic α-helical antimicrobial peptide composed of 13 amino acid residues" "Not found" "Comment: The peptide has strong antibacterial activity against Gram-positive bacteria such as methicillin-resistant Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus capitate, but has almost no activity against Gram-negative bacteria and has very high antibacterial activity. Strong hemolytic activity" "Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=5μmol/L), Staphylococcus aureus ATCC 25923(MIC=5μmol/L), Enterococcus faecalis ATCC 29212(MIC=10μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=10μmol/L, Escherichia coli ATCC 35218(MIC=10μmol/L), Pseudomonas aeruginosa ATCC 27853(MIC=5μmol/L), Klebsiella pneumoniae ATCC 27853(MIC=5μmol/L),acinetobacter baumannii ATCC 19606(MIC=5μmol/L)" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" ":10.13819/j.issn.2096-708X.2021.05.001. " "[J].湖北医药学院学报,2021,40(05):441-445+453.DOI:10.13819/j.issn.2096-708X.2021.05.001." "罗旭东,张凯月,蒋僡雯: LUO Xu-dong ZHANG Kai-yue JIANG Hui-wen LI Fang-yan CHEN Zong-yun " "基于蝎抗菌肽Lausporin-1设计衍生肽以优化其抗“ESKAPE”病原菌活性:Analogues Designed from Scorpion-Derived Peptide Lausporin-3 Exhibit Improved Antimicrobial Activity Against ‘ESKAPE’ Pathogens" "DRAMP37366" "RLLKGLCKSIMKKFLRTI" "18" "NK559777-18" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus (MIC=500μg/mL)##Gram-negative bacteria: Escherichia coli 25922 (MIC=15.6μg/mL), Salmonella typhimurium (MIC=31.25μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2017.09.028. " "[J].中国畜牧兽医,2017,44(09):2739-2746.DOI:10.16431/j.cnki.1671-7236.2017.09.028." "杨霞,张殿卿,宋佳玮:YANG Xia ZHANG Dian-qing SONG Jia-wei XIAO Sheng-zhong SHENG Jin-liang YAN Gen-qiang " "合成绵羊抗菌肽NK-Lysin抗菌活性及其对雏鸡沙门氏菌攻毒的治疗效果研究:Antimicrobial Activity of Synthesized Sheep NK-Lysin Peptides and Its Treatment for Chicken Salmonella Challenge" "DRAMP37367" "VCSKMKLLKRPCQSIMKKFLRRI" "23" "NK7652-23ln" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-" "Not found" "Alpha helix" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Staphylococcus aureus (MIC=500μg/mL)##Gram-negative bacteria: Escherichia coli 25922 (MIC=31.25μg/mL), Salmonella typhimurium (MIC=31.25μg/mL)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.16431/j.cnki.1671-7236.2017.09.028. " "[J].中国畜牧兽医,2017,44(09):2739-2746.DOI:10.16431/j.cnki.1671-7236.2017.09.028." "杨霞,张殿卿,宋佳玮:YANG Xia ZHANG Dian-qing SONG Jia-wei XIAO Sheng-zhong SHENG Jin-liang YAN Gen-qiang " "合成绵羊抗菌肽NK-Lysin抗菌活性及其对雏鸡沙门氏菌攻毒的治疗效果研究:Antimicrobial Activity of Synthesized Sheep NK-Lysin Peptides and Its Treatment for Chicken Salmonella Challenge" "DRAMP37368" "FLQHIIGALTHIF" "13" "Temporin-GHc" "No entry found" "Belongs to the Temporin family" "Not found" "Hylarana guentheri" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Methicillin-resistant Staphylococcus aureus ATCC 43300 (MIC=51.8μmol/L), Staphylococcus aureus ATCC 25923(MIC=12.9μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 44752 (MIC=25.8μmol/L)##Fungus: Candida albicans(MIC=104μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.15886/j.cnki.hdxbzkb.2016.0038. " "[J].海南大学学报(自然科学版),2016,34(03):250-256.DOI:10.15886/j.cnki.hdxbzkb.2016.0038." "董柱,钟亨任,罗文杰: Dong Zhu Zhong Hengren Luo Wenjie Song Yanting Deng Shiming Zhang Yingxia " "海南产沼蛙皮肤temporin家族抗菌肽抗菌活性及稳定性研究:Antimicrobial Activities and Influential Factors of Temporin Family Antimicrobial Peptides Derived from Hylarana guentheri of Hainan" "DRAMP37369" "FIHHIIGALGHLF" "13" "Temporin-GHb" "No entry found" "Belongs to the Temporin family" "Not found" "Hylarana guentheri" "Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: No comments found on DRAMP database" "Gram-positive bacteria: Methicillin-resistant Staphylococcus aureus ATCC 43300 (MIC=26.4μmol/L), Staphylococcus aureus ATCC 25923(MIC=6.8μmol/L)##Gram-negative bacteria: Escherichia coli ATCC 44752 (MIC=6.8μmol/L)##Fungus: Candida albicans(MIC=26.4μmol/L)." "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Amidation" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.15886/j.cnki.hdxbzkb.2016.0038. " "[J].海南大学学报(自然科学版),2016,34(03):250-256.DOI:10.15886/j.cnki.hdxbzkb.2016.0038." "董柱,钟亨任,罗文杰: Dong Zhu Zhong Hengren Luo Wenjie Song Yanting Deng Shiming Zhang Yingxia " "海南产沼蛙皮肤temporin家族抗菌肽抗菌活性及稳定性研究:Antimicrobial Activities and Influential Factors of Temporin Family Antimicrobial Peptides Derived from Hylarana guentheri of Hainan" "DRAMP37370" "GGSGGGSSGGSIGGR" "15" "P-1" "No entry found" "Not found" "Not found" "Bacillus pumilus HN-10" "Antimicrobial, Antibacterial, Antifungal" "Not found" "Not found" "Not found" "Not found" "Comment: The antibacterial peptide P-1 can significantly inhibit the increase of the biomass of T. Roseum. The ultrastructural observation showed that P-1 destroyed the cell wall membrane of T. Roseum spores, and there was a local gap and a large amount of cytoplasm discharge, resulting in a drastic change in the morphology of the spores and an uneven cytoplasm. This may be the main reason that antibacterial peptide P-1 inhibits the growth of T. Roseum." "Fungus: Trichothecium roseum" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.13995/j.cnki.11-1802/ts.027300. " "[J].食品与发酵工业,2021,47(23):83-90.DOI:10.13995/j.cnki.11-1802/ts.027300." "武淑娟,贠建民,王睿: WU Shujuan YUN Jianmin WANG Rui HE Kui MAO Yongqiang ZHAO Fengyun ZHANG Wenwei AI Duiyuan " "短小芽孢杆菌HN-10抗菌肽P-1对粉红单端孢细胞膜结构和活性氧代谢的影响:Effects of antifungal peptide P-1 from Bacillus pumilus HN-10 on cell membrane structure and ROS metabolism of Trichothecium roseum" "DRAMP37371" "GLLKRIKTLLLINLKALALAKKIL" "24" "AM-1" "No entry found" "Not found" "Not found" "Sythetic" "Antimicrobial, Antibacterial, Anti-tumor" "Not found" "Not found" "Not found" "Not found" "Comment: Two new antimicrobial peptides, AM-1 and AM-2, use Leu and Lys residues as linkers respectively to connect MP and Anoplin, forming a new antimicrobial peptide with 25 amino acid residues." "Not found" "No hemolysis information or data found in the reference(s) presented in this entry" "Linear" "Free" "Free" "None" "L" "No cytotoxicity information found" "Cell membrane" "10.19286/j.cnki.cci.2018.11.043. " "[J].煤炭与化工,2018,41(11):140-142.DOI:10.19286/j.cnki.cci.2018.11.043." "刘立伟,朱正煜,张荐益:Liu Liwei Zhu Zhengyu Zhang Jianyi Gao Tengchao " "2条新型抗菌肽的构效关系研究:Study on structure-activity relationship of two novel antibacterial peptides"