DRAMP_ID Sequence Sequence_Length Name Swiss_Prot_Entry Family Gene Source Activity Structure Structure_Description PDB_ID Comments Target_Organism Binding_Traget Pubmed_ID Reference Author Title DRAMP00275 GSSFCDSKCKLRCSKAGLADRCLKYCGICCEECKCVPSGTYGNKHECPCYRDKKNSKGKSKCP 63 Snakin-1 (StSN1; Cys-rich; Plant defensin) "Q948Z4, Q9ZTX6" Unknown SN1 Solanum tuberosum (potato) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Has an antimicrobial activity. Causes a rapid aggregation of both Gram-positive and Gram-negative bacteria, but the antimicrobial activity is not correlated with the capacity to aggregate bacteria. Tissue specificity: Expressed in tubers, stems, axillary and young floral buds, sepals, petals, stamens and carpels, but not in roots, stolons, shoot apex meristem or young leaves. Induction: No responses to methyl jasmonate, ethylene, abscisic acid, salicylic acid, isonicotinic acid, indolacetic acid, gibberellic acid and infection with incompatible bacterial or compatible fungual pathogens. PTM: Six disulfide bonds may be present." "Gram-positive bacteria: Listeria monocytogenes (MIC=10 ?g/mL), Listeria innocua (MIC=10 ?g/mL), Listeria ivanovii (MIC=10 ?g/mL), Clavibacter michiganensis (EC50=1 ?M), Ralstonia solanacearum (rfa-) (EC50=30 ?M), Rhizobium meliloti (EC50=8 ?M).##Fungi: Botrytis cinerea (EC50=2 ?M), Fusarium solani (EC50=3 ?M), Fusarium culmorum (EC50=2 ?M), Fusarium oxysporum f. sp. conglutinans (EC50=10 ?M), Fusarium oxysporum f. sp. lycopersici (EC50=20 ?M), Plectosphaerella cucumerina (EC50=10 ?M), Colletotrichum graminicola (EC50=10 ?M), Colletotrichum lagenarium (EC50=10 ?M), Bipolaris maydis (EC50=20 ?M), Aspergillus flavus (EC50=20 ?M)." Unknown 11891250##9885189 Plant Physiol. 2002 Mar;128(3):951-961.##Mol Plant Microbe Interact. 1999 Jan;12(1):16-23. "Berrocal-Lobo M, Segura A, Moreno M, L??pez G, Garc??a-Olmedo F, Molina A.##Segura A, Moreno M, Madue?㊣o F, Molina A, Garc??a-Olmedo F." "Snakin-2, an antimicrobial peptide from potato whose gene is locally induced by wounding and responds to pathogen infection.##Snakin-1, a peptide from potato that is active against plant pathogens." DRAMP00336 IPCGESCVWIPCITAIAGCSCKNKVCYT 28 ChaC7 (Chassatide C7; uncyclotides; Plant defensin) No entry found Unknown Unknown Chassalia chartacea Unkonw Unknown Unknown Unknown "IC50=1.2 ?M, HD50=11.6 ?M. Note: IC50 (concentration that gives a survival index of 50%) and HD50 (concentration that causes 50% lysis of red blood cells)." "Gram-negative bacterium: Escherichia coli (MIC=6.4 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC>80 ?M), Staphylococcus epidermidis (MIC>80 ?M)." Unknown 22467870 J Biol Chem. 2012 May 18;287(21):17598-17607. "Nguyen GK, Lim WH, Nguyen PQ, Tam JP." Novel Cyclotides and Uncyclotides with Highly Shortened Precursors from Chassalia chartacea and Effects of Methionine Oxidation on Bioactivities. DRAMP00337 AIPCGESCVWIPCISTVIGCSCSNKVCYR 29 ChaC8 (Chassatide C8; uncyclotides; Plant defensin) No entry found Unknown Unknown Chassalia chartacea Unkonw Unknown Unknown Unknown "IC50=1.0 ?M, HD50=25.5 ?M. Note: IC50 (concentration that gives a survival index of 50%) and HD50 (concentration that causes 50% lysis of red blood cells)." "Gram-negative bacterium: Escherichia coli (MIC=6.6 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC>80 ?M), Staphylococcus epidermidis (MIC>80 ?M)." Unknown 22467870 J Biol Chem. 2012 May 18;287(21):17598-17607. "Nguyen GK, Lim WH, Nguyen PQ, Tam JP." Novel Cyclotides and Uncyclotides with Highly Shortened Precursors from Chassalia chartacea and Effects of Methionine Oxidation on Bioactivities. DRAMP00338 IPCGESCVWIPCISGMFGCSCKDKVCYS 28 ChaC11 (Chassatide C11; uncyclotides; Plant defensin) No entry found Unknown Unknown Chassalia chartacea Unkonw Unknown Unknown Unknown "IC50=1.2 ?M, HD50=13.3 ?M. Note: IC50 (concentration that gives a survival index of 50%) and HD50 (concentration that causes 50% lysis of red blood cells)." "Gram-negative bacterium: Escherichia coli (MIC=8.5 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC>80 ?M), Staphylococcus epidermidis (MIC>80 ?M)." Unknown 22467870 J Biol Chem. 2012 May 18;287(21):17598-17607. "Nguyen GK, Lim WH, Nguyen PQ, Tam JP." Novel Cyclotides and Uncyclotides with Highly Shortened Precursors from Chassalia chartacea and Effects of Methionine Oxidation on Bioactivities. DRAMP00384 GNEGGGHGGHGGYGGYHHHGGGGGGYGGYHGGGGS 35 Cc-GRP (Gly-rich; Plants) No entry found Unknown Unknown Coffea canephora Antifungal Rich Unknown Unknown "The sequence displayed is only the N-terminal sequence of 7 kD peptide. The peptide was located in the cell wall, cell surface and nucleus of Fusarium oxysporum. " "Fungi: Candida albicans (MIC=90 ?g/ml), Candida tropicalis (MIC=180 ?g/ml), Colletotrichum lindemuthianum (MIC=90 ?g/ml), Fusarium oxysporium (MIC=90 ?g/ml)." Unknown 23500079 Biochim Biophys Acta. 2013 Mar 15.[Epub ahead of print] "Zottich U, Da Cunha M, Carvalho AO, Dias GB, Casarin N, Vasconcelos IM, Gomes VM." An antifungal peptide from Coffea canephora seeds with sequence homology to glycine-rich proteins exerts membrane permeabilization and nuclear localization in fungi. DRAMP00385 QLPICGETCVLGGCYTPNCRCQYPICVR 28 Panitide L2 (plants) No entry found Unknown Unknown Panicum laxum Antibacterial Bridge Unknown Unknown PTM: N-terminus is a pyruglutamyl. Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=2.5 ?M). Unknown 23195955 J Biol Chem. 2013 Feb 1;288(5):3370-3380. "Nguyen GK, Lian Y, Pang EW, Nguyen PQ, Tran TD, Tam JP." Discovery of linear cyclotides in monocot plant Panicum laxum of Poaceae family provides new insights into evolution and distribution of cyclotides in plants. DRAMP00416 KLCERSSGTWSGVCGNNNACKNQCIRLEGAQHGSCNYVFPAHKCICYFPC 50 Raphanus sativus Antifungal Protein 3 (Rs-AFP3; Plant defensin) "O24332, Q39313" Belongs to the DEFL family AFP3 Raphanus sativus (Radish) & Brassica napus (Rape) Antifungal Bridge Unknown Unknown "Function: Possesses antifungal activity sensitive to inorganic cations (By similarity). PTM: Problely contains four disulfide bonds 3-50; 14-35; 20-44; 24-46." "Fungi: Alternaria brassicicola (MIC=2 ?g/ml), Botrytis cinerea (MIC=2 ?g/ml), Fusarium culmorum (MIC=2 ?g/ml)." Unknown 7780308##8422949 Plant Cell. 1995 May;7(5):573-588.##FEBS Lett. 1993 Feb 1;316(3):233-240. "Terras FR, Eggermont K, Kovaleva V, Raikhel NV, Osborn RW, Kester A, Rees SB, Torrekens S, Van Leuven F, Vanderleyden J, et al.##Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF." Small cysteine-rich antifungal proteins from radish: their role in host defense.##A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species. DRAMP00417 QKLCERSSGTWSGVCGNNNACKNQCINLEGARHGSCNYIFPYHRCICYFPC 51 Raphanus sativus Antifungal Protein 4 (Rs-AFP4; Plant defensin) O24331 Belongs to the DEFL family AFP4 Raphanus sativus (Radish) Antifungal Bridge Unknown Unknown "PTM: Contains four disulfide bonds 4-51;15-36;21-45;25-47, and Pyrrolidone carboxylic acid at position 1." "Fungi: Alternaria brassicicola (MIC=5 ?g/ml), Botrytis cinerea (MIC=9 ?g/ml), Fusarium culmorum (MIC=11 ?g/ml)." Unknown 7780308 Plant Cell. 1995 May;7(5):573-588. "Terras FR, Eggermont K, Kovaleva V, Raikhel NV, Osborn RW, Kester A, Rees SB, Torrekens S, Van Leuven F, Vanderleyden J, et al." Small cysteine-rich antifungal proteins from radish: their role in host defense. DRAMP00422 QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC 51 Defensin-like protein 1 (Sa-AFP1; Plant defensin) P30231 Unknown Unknown Sinapis alba (White mustard) (Brassica hirta) Antifungal Bridge Unknown Unknown Function: Possesses antifungal activity sensitive to inorganic cations. "Fungi: Alternaria brassicola (MIC=1.2 ?g/ml), Botrytis cinerea (MIC=1.8 ?g/ml), Fusarium culmorum (MIC=4 ?g/ml), Fusarium oxysporum f.sp.lycopersici (MIC=6 ?g/ml), Pyricularia oryzae (MIC=0.5 ?g/ml), Verticillium dahliae (MIC=1.5 ?g/ml).##NOTE: In synthetic low ionic strength fungal growth medium." Unknown 8422949##8836771 FEBS Lett. 1993 Feb 1;316(3):233-240.##Int J Pept Protein Res. 1996 Jun;47(6):437-446. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Neumann GM, Condron R, Polya GM." A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Purification and mass spectrometry-based sequencing of yellow mustard (Sinapis alba L.) 6 kDa proteins. Identification as antifungal proteins. DRAMP00423 KLCQRPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC 50 Defensin-like protein 2 (Sa-AFP2; Plant defensin) No entry found Unknown Unknown Sinapis alba (White mustard) (Brassica hirta) Antifungal Unknown Unknown Unknown Function: Possesses antifungal activity sensitive to inorganic cations. "Fungi: Alternaria brassicola (MIC=4.5 ?g/ml), Botrytis cinerea (MIC=3.5 ?g/ml), Fusarium culmorum (MIC=2.3 ?g/ml), Fusarium oxysporum f.sp.lycopersici (MIC=2.3 ?g/ml), Pyricularia oryzae (MIC=0.3 ?g/ml), Verticillium dahliae (MIC=1.2 ?g/ml).##NOTE: In synthetic low ionic strength fungal growth medium." Unknown 8422949 FEBS Lett. 1993 Feb 1;316(3):233-240. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF." A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species. DRAMP00425 LMCTHPLDCSN 11 Tn-AFP1 (Trapa natans antifungal peptide; Plant defensin) No entry found Unknown Unknown Trapa natans Antifungal Unknown Unknown Unknown Tn-AFP1 has no adverse effect on red blood cells at concentration of 32 ??g/mL. Yeast: Candida tropicalis (MIC=32 ?g/ml). Unknown 21736910 Peptides. 2011 Aug;32(8):1741-1747. "Mandal SM, Migliolo L, Franco OL, Ghosh AK." Identification of an antifungal peptide from Trapa natans fruits with inhibitory effects on Candida tropicalis biofilm formation. DRAMP00431 KTCMTKKEGWGRCLIDTTCAHSCRKYGYMGGKCQGITRRCYCLLNC 46 Defensin-like protein 2 (Cp-thionin II; Cp-thionin-2; Gamma-thionin II; Plant defensin) P84920 Belongs to the DEFL family Unknown Vigna unguiculata (Cowpea) Antibacterial Unknown Unknown Unknown "Function: Has antibacterial activity against the Gram-positive bacterium S. aureus and the Gram-negative bacteria E. coli and P. syringae. Does not have antibacterial activity against the phytopathogenic bacteria R. solanacearum, Rhataybacter sp and Erwinia sp. Does not inhibit trypsin, chymotrypsin or alpha-amylases. Tissue specificity: Present in seeds, cotyledons and leaves. Not found in roots or stems. Developmental stage: Present in seeds and seedlings, levels decrease with seedling age. Light increases the rate of degradation. Present until 9 days in seedlings kept in the dark, not found after 6 days in seedings kept in the light. PTM: Contains four disulfide bonds 3-46; 13-33; 19-40; 23-42." "Gram-positive bacterium: Staphylococcus aureus ATTC 25923 (MIC=128 mg/ml);##Gram-negative bacteria: Escherichia coli ATTC 25922 (MIC=64 mg/ml), Pseudomonas syringae (MIC=42 mg/ml)." Unknown 16824043 FEBS J. 2006 Aug;273(15):3489-3497. "Franco OL, Murad AM, Leite JR, Mendes PA, Prates MV, Bloch C Jr." Identification of a cowpea gamma-thionin with bactericidal activity. DRAMP00436 KTCEHLADTYRGVCFTNASCDDHCKNKAHLISGTCHNWKCFCTQNC 46 Pisum sativum defensin 1 (Psd1; Plant defensin) P81929 Belongs to the DEFL family Unknown Pisum sativum (Garden pea) Antifungal Combine helix and strand structure The protein has a globular fold with a triple-stranded antiparalell beta-sheet and an alpha-helix (from residue Asn17 to Leu27). 1JKZ resolved by NMR. PTM: Contains four disulfide bonds 3-46; 14-35; 20-40; 24-42. "PD: Aspergillus niger (MIC=12.1 ?g/ml), Aspergillus versicolor (MIC<5.0 ?g/ml), Fusarium moniliforme (MIC=21.7 ?g/ml), Fusarium oxysporum (MIC>100 ?g/ml), Fusarium solani (MIC=12.1 ?g/ml), Neurospora crassa (MIC=0.04 ?g/ml), Saccharomyces cerevisae (MIC>100 ?g/ml), Trichophyton mentagrophytes (MIC>100 ?g/ml).##PD+: Aspergillus niger (MIC=7.4 ?g/ml), Fusarium moniliforme (MIC=33.2 ?g/ml), Fusarium oxysporum (MIC=100 ?g/ml), Fusarium solani (MIC=79.2 ?g/ml), Neurospora crassa (MIC=0.05 ?g/ml).##NOTE: PD+: potato dextrose medium supplemented with 1 mM CaCl2." It interacts with cell-cycle-realted protein cyclin F as the target. 10860545##11697857##11812144 Arch Biochem Biophys. 2000 Jun 15;378(2):278-286.##Arch Biochem Biophys. 2001 Nov 15;395(2):199-207.##J Mol Biol. 2002 Jan 25;315(4):749-757. "Almeida M.S, Cabral K.M, Zingali R.B, Kurtenbach E.##Almeida MS, Cabral KS, de Medeiros LN, Valente AP, Almeida FC, Kurtenbach E.##Almeida MS, Cabral KM, Kurtenbach E, Almeida FC, Valente AP." "Characterization of two novel defense peptides from pea (Pisum sativum) seeds.##cDNA cloning and heterologous expression of functional cysteine-rich antifungal protein Psd1 in the yeast Pichia pastoris.##Solution structure of Pisum sativum defensin 1 by high resolution NMR: plant defensins, identical backbone with different mechanisms of action." DRAMP00437 KTCENLSGTFKGPCIPDGNCNKHCRNNEHLLSGRCRDDFRCWCTNRC 47 Pisum sativum defensin 2 (Psd2; Plant defensin) P81930 Belongs to the DEFL family Unknown Pisum sativum (Garden pea) Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds 3-47; 14-35; 20-41; 24-43. "PD: Aspergillus niger (MIC=10.2 ?g/ml), Aspergillus versicolor (MIC=0.34 ?g/ml), Fusarium moniliforme (MIC=10.0 ?g/ml), Fusarium oxysporum (MIC>100 ?g/ml), Fusarium solani (MIC=8.5 ?g/ml), Neurospora crassa (MIC<0.5 ?g/ml), Saccharomyces cerevisae (MIC>100 ?g/ml), Trichophyton mentagrophytes (MIC<100 ?g/ml).##PD+: Aspergillus niger (MIC=7.8 ?g/ml), Aspergillus versicolor (MIC=5.9 ?g/ml), Fusarium moniliforme (MIC=25 ?g/ml), Fusarium oxysporum (MIC>100 ?g/ml), Fusarium solani (MIC=5.0 ?g/ml).##NOTE: PD+ = potato dextrose medium supplemented with 1 mM CaCl2." Unknown 10860545 Arch Biochem Biophys. 2000 Jun 15;378(2):278-286. "Almeida M.S, Cabral K.M, Zingali R.B, Kurtenbach E." Characterization of two novel defense peptides from pea (Pisum sativum) seeds. DRAMP00450 QKLCQRPSGTWSGVCGNNNACRNQCINLEKARHGSCNYVFPAHKCICYFPC 51 Defensin-like protein 2A (AFP2A; M2A; Plant defensin) P30232 Belongs to the DEFL family Unknown Sinapis alba (White mustard) (Brassica hirta) Antifungal Rich Unknown Unknown "Function: Possesses antifungal activity sensitive to inorganic cations. Subunit structure: Forms oligomers in its native state. PTM: Contains four disulfide bonds (By similarity)." "Fungi: Alternaria brassicola (MIC=4.5 ?g/ml), Botrytis cinerea (MIC=3.5 ?g/ml), Fusarium culmorum (MIC=2.3 ?g/ml), Fusarium oxysporum f.sp. lycopersici (MIC=2.3 ?g/ml), Pyricularia oryzae (MIC=0.3 ?g/ml), Verticillium dahliae (MIC=1.2 ?g/ml)." Unknown 8422949##8836771 FEBS Lett. 1993 Feb 1;316(3):233-240.##Int J Pept Protein Res. 1996 Jun;47(6):437-446. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Neumann GM, Condron R, Polya GM." A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Purification and mass spectrometry-based sequencing of yellow mustard (Sinapis alba L.) 6 kDa proteins. Identification as antifungal proteins. DRAMP00454 ATCKAECPTWDSVCINKKPCVACCKKAKFSDGHCSKILRRCLCTKEC 47 Petunia hybrida defensin 1 (PhD1; Cys-rich; Plant defensin) Q8H6Q1 Belongs to the DEFL family D1 Petunia hybrida (Petunia) Antifungal Combine helix and strand structure "PhD1 has the fold of the cysteine-stabilized alphabeta motif, consisting of an alpha-helix and a triple-stranded antiparallel beta-sheet, except that it contains a fifth disulfide bond from the first loop to the alpha-helix." 1N4N resolved by NMR. "Function: Plant defense peptide with antifungal activity. Tissue specificity: Petals. Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. Biophysicochemical properties: pH dependence (Stable under extremes of pH); Temperature dependence (Stable under extremes of temperature). PTM: Contains five disulfide bonds 3-47; 7-23; 14-34; 20-41; 24-43." "Fungi: Fusarium oxysporum (MIC=10 ?g/ml), Botrytis cinerea (MIC=10 ?g/ml)." Unknown 12644678#12846570 Plant Physiol. 2003 Mar;131(3):1283-1293.##Biochemistry. 2003 Jul 15;42(27):8214-8222. "Lay FT, Brugliera F, Anderson MA.##Janssen BJ, Schirra HJ, Lay FT, Anderson MA, Craik DJ." "Isolation and properties of floral defensins from ornamental tobacco and petunia.##Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds." DRAMP00764 KSLRPRCWIKIKFRCKSLKF 20 Piceain 1 (Plants) No entry found Unknown Unknown Picea sitchensis "Antibacterial, Antifungal" Beta strand (CD) Unknown Unknown "Function: Active against both Gram-postive and Gram-negative bacteria, fungi. It showed weak hemolysis activity against human and rabbit red cells. PTM: Contains one disulfide bond." "Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=9.38 ?g/ml), S. aureus ATCC 43300 (MIC=9.38 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=18.75 ?g/ml), Escherichia coli ML-35P (MIC=18.75 ?g/ml), Escherichia coli 08040722 (CI) (MIC=75 ?g/ml), Escherichia coli 08A866 (CI) (MIC=37.5 ?g/ml), Pseudomonas aeruginosa PA01 (MIC=9.38 ?g/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=9.38 ?g/ml), Pseudomonas aeruginosa 08031014 (CI) (MIC=37.5 ?g/ml).##Yeast: Candida albicans ATCC 20032 (MIC=9.38 ?g/ml)." Unknown 21644248 J Pept Sci. 2011 Sep;17(9):627-631. "Liu R, Mu L, Liu H, Wei L, Yan T, Chen M, Zhang K, Li J, You D, Lai R." Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis. DRAMP00765 RPRCWIKIKFRCKSLKF 17 Piceain 2 (Plants) No entry found Unknown Unknown Picea sitchensis "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Active against both Gram-postive and Gram-negative bacteria, fungi. It showed weak hemolysis activity against human and rabbit red cells. PTM: Contains one disulfide bond." "Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=9.38 ?g/ml), S. aureus ATCC 43300 (MIC=18.75 ?g/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=37.5 ?g/ml), Escherichia coli ML-35P (MIC=37.5 ?g/ml), Escherichia coli 08040722 (CI) (MIC=75 ?g/ml), Escherichia coli 08A866 (CI) (MIC=37.5 ?g/ml), Pseudomonas aeruginosa PA01 (MIC=9.38 ?g/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=18.75 ?g/ml), Pseudomonas aeruginosa 08031014 (CI) (MIC=37.5 ?g/ml).##Yeast: Candida albicans ATCC 20032 (MIC=18.75 ?g/ml)." Unknown 21644248 J Pept Sci. 2011 Sep;17(9):627-631. "Liu R, Mu L, Liu H, Wei L, Yan T, Chen M, Zhang K, Li J, You D, Lai R." Two antimicrobial and nematicidal peptides derived from sequences encoded Picea sitchensis. DRAMP00766 KVFLGLK 7 JCpep7 (Plants) No entry found Unknown Unknown Jatropha curcas Unkonw Unknown Unknown Unknown "Function: JCpep7 killed microbes principally via breaking of their cell walls and membranes, followed by cell lysis." "Gram-negative bacteria: Salmonella typhimurium ATCC 50013 (MIC=48 ?g/ml), Shigella dysenteriae ATCC 51302 (MIC=48 ?g/ml), Pseudomonas aeruginosa ATCC 27553 (MIC=64 ?g/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=40 ?g/ml), Bacillus subtilis ATCC 23631 (MIC=24 ?g/ml), Streptococcus pneumoniae ATCC 49619 (MIC=56 ?g/ml)." Unknown 21268582 J Agric Food Chem. 2011 Feb 23;59(4):1145-1151. "Xiao J, Zhang H, Niu L, Wang X." Efficient Screening of a Novel Antimicrobial Peptide from Jatropha curcas by Cell Membrane Affinity Chromatography. DRAMP00774 GTRCGETCFVLPCWSAKFGCYCQKGFCYRN 30 Hedyotide B1 (hB1; Plants) No entry found Belongs to the cyclotide family Unknown Hedyotis biflora (aerial tissues) Antibacterial Unknown Unknown Unknown No comments found on DRAMP database "Gram-negative bacterium: Escherichia coli (MIC=3.4 ?M);##Gram-positive bacteria: Streptococcus salivarius(MIC=5.9 ?M), Staphylococcus epidermidis (MIC>80 ?M), S. aureus (MIC>80 ?M)." Unknown 21979955 J Biol Chem. 2011 Dec 30;286(52):44833-44844. "Nguyen GK, Zhang S, Wang W, Wong CT, Nguyen NT, Tam JP." Discovery of a linear cyclotide from the bracelet subfamily and its disulfide mapping by top-down mass spectrometry. DRAMP00795 GIPCGESCVFIPCITAAIGCSCKSKVCYRN 30 Cliotide T1 (cT1; Plant defensin) No entry found Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) "Antibacterial, Anticancer" Unknown Unknown Unknown "Function: Cliotide T1 shows stronger antimicrobial activity against the Gram-negative bacteria than the Gram-positive bacteria. It also has hemolytic activity against human type A erythrocytes (HD50=7.1 ?M) and cytotoxicity against HeLa Cells (IC50=0.6 ?M). [Note: HD50 refers to the peptide concentration that causes 50% lysis of red blood cells; IC50 refers to the peptide concentration that causes 50% death of HeLa cells]. " "Gram-positive bacteria: Staphylococcus aureus ATCC12600, Enterococcus faecalis ATCC 47077 (less active);##Gram-negative bacteria: Escherichia coli ATCC 700926 (MIC=1.1 ?M), Pseudomonas aeruginosa ATCC 39018 (MIC=2.7 ?M), Klebsiella pneumonia ATCC 13883 (MIC=4.7 ?M)." Unknown 21596752 J Biol Chem. 2011 Jul 8;286(27):24275-24287. "Nguyen GK, Zhang S, Nguyen NT, Nguyen PQ, Chiu MS, Hardjojo A, Tam JP." Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family. DRAMP00798 GIPCGESCVFIPCITGAIGCSCKSKVCYRN 30 Cliotide T4 (cT4; Plant defensin) No entry found Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) "Antibacterial, Anticancer" Unknown Unknown Unknown "Function: Cliotide T4 shows stronger antimicrobial activity against the Gram-negative bacteria than the Gram-positive bacteria. It also has hemolytic activity against human type A erythrocytes (HD50=8.4 ?M) and cytotoxicity against HeLa Cells (IC50=0.6 ?M). [Note: HD50 refers to the peptide concentration that causes 50% lysis of red blood cells; IC50 refers to the peptide concentration that causes 50% death of HeLa cells]. " "Gram-positive bacteria: Staphylococcus aureus ATCC12600, Enterococcus faecalis ATCC 47077 (less active);##Gram-negative bacteria: Escherichia coli ATCC 700926 (MIC=1.3 ?M), Pseudomonas aeruginosa ATCC 39018 (MIC=1.9 ?M), Klebsiella pneumonia ATCC 13883 (MIC=1.5 ?M)." Unknown 21596752 J Biol Chem. 2011 Jul 8;286(27):24275-24287. "Nguyen GK, Zhang S, Nguyen NT, Nguyen PQ, Chiu MS, Hardjojo A, Tam JP." Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family. DRAMP00856 GLPVCGETCVGGTCNTPGCTCSWPVCTRN 29 Kalata-B1 (Plant defensin) P56254 Belongs to the cyclotide family OAK1 Oldenlandia affinis "Antibacterial, Antifungal, Insecticidal" Beta strand (3 strands; 7 residues) Unknown 2KHB resolved by NMR. "Function: Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S. aureus. Relatively ineffective against Gram-negative bacteria such as E. coli and P. aeruginosa. Inhibitory effect on the growth and development of larvae from H. punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost. MOA: a small number of cyclotides bind to the membrane surface and then insert first into the outer membrane leaflet followed by penetration through the membrane and pore formation. At higher concentrations of cyclotides, destabilization of membranes occurs. Tissue specificity: Leaves and stems. Lower in roots. Pharmaceutical use: The uteroactive properties of Kalata have been discovered by African traditional medicine. It is used as an ingredient of a herbal tea to accelerate childbirth. PTM: Kalata-B1 is a cyclic peptide which contains three disulfide bonds 5-19; 11-21; 14-26." "Gram-positive bacteria: Staphylococcus aureus (MIC=0.26 ?M), Micrococcus luteus (MIC=40.4 ?M);##Gram-negative bacterium: Klebsiella oxytoca (MIC=54.8 ?M).##Fungi: Candida kefyr (MIC=21.4 ?M).##Insects: Helicoverpa punctigera Larvae (0.8 ?M/g diet)." Cell membrance 10430870##7703226##17534989##12779323##23129773 Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8918.##Biochemistry. 1995 Apr 4;34(13):4147-4158.##Chembiochem. 2007 Jun 18;8(9):1001-1011.##Biochemistry. 2003 Jun 10;42(22):6688-6695.##J Biol Chem. 2012 Dec 21;287(52):43884-98. "Tam JP, Lu YA, Yang JL, Chiu KW.##Saether O, Craik DJ, Campbell ID, Sletten K, Juul J, Norman DG.##Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ.##Barry DG, Daly NL, Clark RJ, Sando L, Craik DJ.##Wang CK, Wacklin HP, Craik DJ." "An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides.##Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1.##The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides.##Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity.##Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane through hydrophobic and phosphoethanolamine-specific interactions." DRAMP00877 GIPCGESCVWIPCISAALGCSCKNKVCYRN 30 Circulin-A (CIRA; Plant defensin) "P56871, P82250" Belongs to the cyclotide family Unknown Chassalia parviflora "Antibacterial, Antifungal, Antiviral" Alpha helix (1 helices; 4 residues) "The molecule is stabilised by three disulfide bonds, two of which form an embedded loop completed by the backbone fragments connecting the cysteine residues. A third disulfide bond threads through the centre of this loop to form a ""cystine-knot"" motif. This motif is present in a range of other biologically active proteins, including omega-contoxin GVIA and Cucurbita maxima trypsin inhibitor." 1BH4 resolved by NMR. "Function: Probably participates in a plant defense mechanism. Has antibiotic activity. Inhibits the cytopathic effects and replication of the human immunodeficiency virus. Relatively ineffective against Gram-negative bacteria such as E. coli and P. aeruginosa. PTM: This is a cyclic peptide which contains three disulfide bonds 1-17; 5-19; 10-24." Gram-positive bacterium: Staphylococcus aureus (MIC=0.19 ?M).##Gram-negative bacterium: Proteus vulgaris (MIC=54.6 ?M).##Fungi: Candida kefyr (MIC=18.6 ?M) and Candida tropicalis (MIC=19.4 ?M).##NOTE: Medium with 10 mM phosphate buffer. Unknown 10430870##9878410 Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8918.##J. Mol. Biol. 1999; 285:333-345. "Tam JP, Lu YA, Yang JL, Chiu KW.##Daly NL, Koltay A, Gustafson KR, Boyd MR, Casas-Finet JR, Craik DJ." An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides.##Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity. DRAMP00878 GVIPCGESCVFIPCISTLLGCSCKNKVCYRN 31 Circulin-B (CIRB; Plant defensin) "P56879, P82255" Belongs to the cyclotide family Unknown Chassalia parviflora "Antibacterial, Antifungal, Antiviral" Beta strand (5 strands; 10 residues) Cyclotides are mini-proteins derived from plants that have the characteristic features of a head-to-tail cyclised peptide backbone and a knotted arrangement of their three disulfide bonds. 2ERI resolved by NMR. "Function: Probably participates in a plant defense mechanism. Has antibiotic activity. Inhibits the cytopathic effects and replication of the human immunodeficiency virus. Active against both Gram-positive and Gram-negative bacteria. PTM: This is a cyclic peptide which contains three disulfide bonds 5-21; 9-23; 14-28." "Gram-positive bacterium: (L-salt): Staphylococcus aureus (MIC=13.5 ?M).##Gram-negative bacteria: (L-salt, H-salt) (MIC ?M): Escherichia coli (0.41, >500), Pseudomonas aeruginosa (25.5, 48), Proteus vulgaris (6.8, >500), Klebsiella oxytoca (8.2, 15.6).##Fungi (H-salt): Candida kefyr (MIC=29 ?M).##NOTE: L-salt = Medium with 10 mM phosphate buffer; H-salt = L-salt supplemented with 100 mM NaCl." Unknown 10430870## Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8918.##Int. J. Pept. Protein Res. 2005;11:99-106. "Tam JP, Lu YA, Yang JL, Chiu KW.##Koltay A, Daly N.L, Gustafson K.R, Craik D.J." An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides.##Structure of circulin B and implications for antimicrobial activity of the cyclotides. DRAMP00931 TCSYTMEA 8 Antimicrobial peptide 3 (Cn-AMP3; Plant defensin) P86707 Unknown Unknown Cocos nucifera (Coconut palm) "Antibacterial, Anti-Gram+, Anti-Gram-" Unknown Unknown Unknown "Function: Antibacterial activity against Gram-negative and Gram-positive bacteria. Tissue specificity: Found in the liquid endosperm contained in green fruit of coconut palms, also known as coconut water (at protein level). Subunit structure: Monomer." [Ref.19111587] Gram-positive bacteria: Bacillus subtilis (MIC=257 Unknown 19111587 Peptides. 2009 Apr;30(4):633-637. "Mandal SM, Dey S, Mandal M, Sarkar S, Maria-Neto S, Franco OL." Identification and structural insights of three novel antimicrobial peptides isolated from green coconut water. DRAMP00930 TESYFVFSVGM 11 Antimicrobial peptide 2 (Cn-AMP2; Plant defensin) P86706 Unknown Unknown Cocos nucifera (Coconut palm) "Antibacterial, Anti-Gram+, Anti-Gram-" Unknown Unknown Unknown "Function: Antibacterial activity against Gram-negative and Gram-positive bacteria. Tissue specificity: Found in the liquid endosperm contained in green fruit of coconut palms, also known as coconut water (at protein level). Subunit structure: Monomer." [Ref.19111587] Gram-positive bacteria: Bacillus subtilis (MIC=150 Unknown 19111587 Peptides. 2009 Apr;30(4):633-637. "Mandal SM, Dey S, Mandal M, Sarkar S, Maria-Neto S, Franco OL." Identification and structural insights of three novel antimicrobial peptides isolated from green coconut water. DRAMP00929 SVAGRAQGM 9 Antimicrobial peptide 1 (Cn-AMP1; Plant defensin) P86705 Unknown Unknown Cocos nucifera (Coconut palm) "Antibacterial, Anti-Gram+, Anti-Gram-" Helix Unknown 2N0V resolved by NMR. "Function: Antibacterial activity against Gram-negative and Gram-positive bacteria. Tissue specificity: Found in the liquid endosperm contained in green fruit of coconut palms, also known as coconut water (at protein level). Subunit structure: Monomer." [Ref.19111587] Gram-positive bacteria: Bacillus subtilis (MIC=76 Unknown 19111587 Peptides. 2009 Apr;30(4):633-637. "Mandal SM, Dey S, Mandal M, Sarkar S, Maria-Neto S, Franco OL." Identification and structural insights of three novel antimicrobial peptides isolated from green coconut water. DRAMP00933 SAFTVWSGPGCNNRAERYSKCGCSAIHQKGGYDFSYTGQTAALYNQAGCSGVAHTRFGSSARACNPFGWKSIFIQC 76 Antimicrobial peptide 1 (AMP1; MiAMP1; Plant defensin) "P80915, O04396" Unknown Unknown Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Combine helix and strand structure MiAMP1 is made up of eight beta-strands which are arranged in two Greek key motifs. These Greek key motifs associate to form a Greek key beta-barrel. This structure is unique amongst plant antimicrobial proteins and forms a new class which we term the beta-barrelins. (Ref.2) 1C01 resolved by NMR. "Function: Antimicrobial peptide which inhibits the growth of a variety of fungi, oomycetes, Gram-positive bacterial phytopatogenes and S.cerevisiae in vitro. No activity against E.coli. Miscellaneous: Its antimicrobial activity is diminished by calcium an" "Alternaria helianthi (MIC=2-5 ?g/ml), Botrytis cinerea (MIC=5-10 ?g/ml), Ceratocystis parodoxa (MIC=20 ?g/ml), Colletotrichum gloeosporioides (MIC=2-5 ?g/ml), Fusurium oxysporum (MIC=2-5 ?g/ml), Leptosphaeria maculans (MIC=5 ?g/ml), Macrophomina phaseolina (MIC<25 ?g/ml), Phytophthoru cryptogea (MIC=5-10 ?g/ml), Pythium graminicola (MIC=5 ?g/ml), Sclerotinia sclerotiorum spores (MIC=5 ?g/ml), Sclerotinia sclerotiorum mycelia (MIC=50 ?g/ml), Verticilium dahliae (MIC=2 ?g/ml), Clavibacter michiganensis (MIC<10 ?g/ml), Saccharomyces cerevisiae (MIC=2-5 ?g/ml)." Unknown 9108242##10543955 Eur J Biochem. 1997 Mar 15;244(3):743-749.##J Mol Biol. 1999 Oct 29;293(3):629-638. "Marcus JP, Goulter KC, Green JL, Harrison SJ, Manners JM.##McManus AM, Nielsen KJ, Marcus JP, Harrison SJ, Green JL, Manners JM, Craik DJ." "Purification, characterisation and cDNA cloning of an antimicrobial peptide from Macadamia integrifolia.##MiAMP1, a novel protein from Macadamia integrifolia adopts a Greek key beta-barrel fold unique amongst plant antimicrobial proteins." DRAMP01004 PQRGEGGRAGNLLREEQEI 19 Cucurmoschin (Plants) P84158 Unknown Unknown Cucurbita maxima (winter squash) Antifungal Unknown Unknown Unknown Function: Has antifungal activity. Inhibits cell-free translation in rabbit reticulocyte lysate system. "Fungi: Botrytis cinerea (MIC=375 ?M), Fusarium oxysporum (MIC=375 ?M), Mycosphaerella arachidicola (MIC=375 ?M)." Unknown 14499274 Peptides. 2003 Jul;24(7):969-972. "Wang HX, Ng TB." "Isolation of cucurmoschin, a novel antifungal peptide abundant in arginine, glutamate and glycine residues from black pumpkin seeds." DRAMP01012 RESPSSRMECYEQAERYGYGGYGGGRYGGGYGSGRGQPVGQGVERSHDDNRNQPR 55 Pg-AMP (Gly-rich; Plants) P86030 Unknown Unknown Psidium guajava (Guava) Antibacterial Unknown Unknown Unknown "Function: Has antibacterial activity against the Gram-negative bacteria. Does not have antifungal activity against the human and plant pathogenic fungi F. oxysporum, A. fumigatus and R. solani. Subunit structure: Monomer and homodimer. Might act by homodimer formation." "Gram-negative bacteria: Klebsiella sp., Proteus sp., Escherichia coli ATCC 8739 (MIC=72 mg/ml), Klebsiella pneumoniae (MIC=32 mg/ml)." Unknown 18448201 Peptides. 2008 Aug;29(8):1271-1279. "Pelegrini PB, Murad AM, Silva LP, Dos Santos RC, Costa FT, Tagliari PD, Bloch C Jr, Noronha EF, Miller RN, Franco OL." Identification of a novel storage glycine-rich peptide from guava (Psidium guajava) seeds with activity against Gram-negative bacteria. DRAMP01016 QCIGNGGRCNENVGPPYCCSGFCLRQPGQGYGYCKNR 37 Antimicrobial peptide 1 (MJ-AMP1; Plant defensin) P25403 Belongs to the AMP family AMP1 Mirabilis jalapa (Garden four-o'clock) "Antibacterial, Antifungal" Bridge Unknown Unknown "Function: Possesses antifungal activity and is also active on two tested Gram-positive bacteria: but is non-toxic for Gram-negative bacteria and cultured human cells. Tissue specificity: Found only in seeds. PTM: Contains three disulfide bonds 2-19; 9-23;" "Fungi: Alternaria brassicola (MIC=20 ?g/ml), Ascochyta pisi (MIC=200 ?g/ml), Botrytis cinerea (MIC=50 ?g/ml), Cercospora beticola (MIC=10 ?g/ml), Colletotrichum lindemuthianum (MIC=6 ?g/ml), Fusarium culmorum (MIC=30 ?g/ml), Fusarium oxysporum f.sp.pisi (MIC=15 ?g/ml), Fusarium oxysporum f.sp.lycopersici (MIC=200 ?g/ml), Nectria haematococca (MIC=15 ?g/ml), Phoma betae (MIC=25 ?g/ml), Pyrenophora tritici-repentis (MIC=300 ?g/ml), Pyricularia oryzae (MIC=6 ?g/ml), Rhizoctonia solani (MIC=60 ?g/ml), Verticillium dahliae (MIC=12 ?g/ml), Venturia inequalis (MIC=12 ?g/ml).##Gram-positive bacteria: Bacillus megaterium (MIC=6 ?g/ml), Sarcina lutea (MIC=100 ?g/ml)." Unknown 1733929##7647302 J. Biol. Chem. 1992;267:2228-2233.##Plant Mol. Biol. 1995;28:713-721. "Cammue B.P.A, de Bolle M.F.C, Terras F.R.G, Proost P, van Damme J, Rees S.B, Vanderleyden J, Broekaert W.F.##de Bolle M.F, Eggermont K, Duncan R.E, Osborn R.W, Terras F.R.G, Broekaert W.F." Isolation and characterization of a novel class of plant antimicrobial peptides from Mirabilis jalapa L. seeds.##Cloning and characterization of two cDNA clones encoding seed-specific antimicrobial peptides from Mirabilis jalapa L. DRAMP01017 CIGNGGRCNENVGPPYCCSGFCLRQPNQGYGVCRNR 36 Antimicrobial peptide 2 (MJ-AMP2; Plant defensin) P25404 Belongs to the AMP family AMP2 Mirabilis jalapa (Garden four-o'clock) "Antibacterial, Antifungal" Bridge Unknown Unknown Function: Possesses antifungal activity and is also active on two tested Gram-positive bacteria: but is non-toxic for Gram-negative bacteria and cultured human cells. Tissue specificity: Found only in seeds. PTM: Contains three disulfide bonds 1-18; 8-22; "Fungi: Alternaria brassicola (MIC=6 ?g/ml), Ascochyta pisi (MIC=6 ?g/ml), Botrytis cinerea (MIC=2 ?g/ml), Cercospora beticola (MIC=2 ?g/ml), Colletotrichum lindemuthianum (MIC=1 ?g/ml), Fusarium culmorum (MIC=3 ?g/ml), Fusarium oxysporum f.sp.pisi (MIC=5 ?g/ml), Fusarium oxysporum f.sp.lycopersici (MIC=10 ?g/ml), Nectria haematococca (MIC=0.5 ?g/ml), Phoma betae (MIC=6 ?g/ml), Pyrenophora tritici-repentis (MIC=20 ?g/ml), Pyricularia oryzae (MIC=0.5 ?g/ml), Rhizoctonia solani (MIC=15 ?g/ml), Verticillium dahliae (MIC=0.5 ?g/ml), Venturia inequalis (MIC=1 ?g/ml).##Gram-positive bacteria: Bacillus megaterium (MIC=2 ?g/ml), Sarcina lutea (MIC=50 ?g/ml)." Unknown 1733929##7647302 J Biol Chem. 1992 Feb 5;267(4):2228-2233.##Plant Mol Biol. 1995 Jul;28(4):713-721. "Cammue BP, De Bolle MF, Terras FR, Proost P, Van Damme J, Rees SB, Vanderleyden J, Broekaert WF.##De Bolle MF, Eggermont K, Duncan RE, Osborn RW, Terras FR, Broekaert WF." Isolation and characterization of a novel class of plant antimicrobial peptides form Mirabilis jalapa L. seeds.##Cloning and characterization of two cDNA clones encoding seed-specific antimicrobial peptides from Mirabilis jalapa L. DRAMP01018 SIPCGESCVFIPCTVTALLGCSCKSKVCYKN 31 Cyclopsychotride-A (CPT; Plant defensin) "P56872, P82254" Unknown Unknown Psychotria longipes "Antibacterial, Antifungal" Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has antibiotic activity. Inhibits the cytopathic effects and replication of the human immunodeficiency virus. Active against both Gram-positive and Gram-negative bacteria. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28." "Gram-negative bacteria: Escherichia coli (MIC=1.55 ?M), Pseudomonas aeruginosa (MIC=13.5 ?M), Proteus vulgaris (MIC=13.2 ?M), Klebsiella oxytoca (MIC=5.80 ?M).##Gram-positive bacteria: Staphylococcus aureus (MIC=39.0 ?M), Micrococcus luteus (MIC=48.0 ?M).##Fungi: Candida albicans (MIC>500 ?M), Candida kefyr (MIC=14.0 ?M), Candida tropicalis (MIC=56.5 ?M).##NOTE: Medium with 10 mM phosphate buffer." Unknown 10430870##7714530 Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8918.##J Nat Prod. 1994 Dec;57(12):1619-1625. "Tam JP, Lu YA, Yang JL, Chiu KW.##Witherup KM, Bogusky MJ, Anderson PS, Ramjit H, Ransom RW, Wood T, Sardana M. " "An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides.##Cyclopsychotride A, a biologically active, 31-residue cyclic peptide isolated from Psychotria longipes." DRAMP01061 SRSELIVHQR 10 Antifungal peptide (Cm-p1; Plants) B3EWI7 Unknown Unknown Cenchritis muricatus (Beaded periwinkle) Antifungal Unknown Unknown Unknown Function: The synthetic peptide has antifungal activity. Has no antibacterial or cytotoxic activity. "Fungi: Botrytis cinerea (MIC=20 ?M), Fusarium oxysporum (MIC=20 ?M), Aspergillus niger (MIC=41 ?M), Candida albicans 01U (MIC=13 ?M), C. albicans 38U (MIC=7 ?M), C. parapsilosis (MIC=105 ?M), C. neoformans strain L26 (MIC=209 ?M), C. neoformans strain L30 (MIC=209 ?M), Trichophyton rubrum (MIC=3 ?M)." Unknown 22210491 Biochimie. 2012 Apr;94(4):968-974. "L車pez-Abarrategui C, Alba A, Silva ON, Reyes-Acosta O, Vasconcelos IM, Oliveira JT, Migliolo L, Costa MP, Costa CR, Silva MR, Garay HE, Dias SC, Franco OL, Otero-Gonz芍lez AJ." Functional characterization of a synthetic hydrophilic antifungal peptide derived from the marine snail Cenchritis muricatus. DRAMP01063 LMCTHPLDCSN 11 Antifungal peptide 1 (Tn-AFP1; Plants) B3EWE8 Unknown Unknown Trapa natans (Water chestnut) Antifungal Unknown Unknown Unknown Function: Has antifungal activity including the inhibition of biofilm formation. Has virtually no hemolytic activity against mouse erythrocytes. Yeast: Candida tropicalis (MIC=32 ?g/ml). Unknown 21736910 Peptides. 2011 Aug;32(8):1741-1747. "Mandal SM, Migliolo L, Franco OL, Ghosh AK." Identification of an antifungal peptide from Trapa natans fruits with inhibitory effects on Candida tropicalis biofilm formation. DRAMP01064 AWKLFDDGV 9 Anticancerous peptide 1 (Cr-ACP1; Plants) B3EWE7 Unknown Unknown Cycas revoluta (Sago palm) "Anticancer, Antibacterial" Unknown Unknown Unknown "Function: The synthetic peptide inhibits cell proliferation and induces apoptosis in cancer-derived cell lines Hep2 (IC50=1.5 mM) and HCT15 and, to a lesser extent, in non-cancerous NIH/3T3 cells. The mode of action is presumably an arrest in the G0/G1 phase. Antiproliferative, proapoptotic and DNA-binding activities are increased by acetylation at Ala-1 and Lys-3. Has no hemolytic activity against mouse erythrocytes. Has antibacterial activity. Antibacterial activity is decreased by acetylation. " "Gram-positive bacteria: Staphylococcus epidermidis (MIC=60 ?g), Bacillus subtilis (MIC=30 ?g);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=30 ?g), EEscherichia coli strain ATCC 8739 (MIC=30 ?g)." DNA 21882228 J Cell Biochem. 2012 Jan;113(1):184-193. "Mandal SM, Migliolo L, Das S, Mandal M, Franco OL, Hazra TK." Identification and characterization of a bactericidal and proapoptotic peptide from Cycas revoluta seeds with DNA binding properties. DRAMP01066 PVVDTTGNNPLQQQEEYYV 19 Kunitz-type serine protease inhibitor 1 (Xb-KTI; Plants) P86930 Unknown Unknown Xanthosoma sagittifolium (Elephant's ear) (Arum sagittifolium) Antibacterial Unknown Unknown Unknown Function: Serine protease inhibitor. Displays antimicrobial activity against the Gram-negative bacterium S. typhimurium ATCC 14028. Displays no hemolytic activity. Gram-negative bacterium: Salmonella typhimurium ATCC 14028 (MIC=10 ?M). Unknown 21520894 J Nat Prod. 2011 May 27;74(5):969-975. "Lima TB, Silva ON, Migliolo L, Souza-Filho CR, Gon?alves EG, Vasconcelos IM, Oliveira JT, Amaral AC, Franco OL." A Kunitz proteinase inhibitor from corms of Xanthosoma blandum with bactericidal activity. DRAMP00262 LGKFSQTCYNSAIQGSVLTSTCERTNGGYNTSSIDLNSVIENVDGSLKWQPSNFIETCRNTQLAGSSELAAECKTRAQQFVSTKINLDDHIANIDGTLKYE 101 Cyanovirin-N (CV-N) P81180 Belongs to the cyanovirin-N family Unknown Nostoc ellipsosporum (cyanobacterium) Antiviral Combine helix and strand structure Unknown 2EZM resolved by NMR. "Function: Mannose-binding lectin. Biotechnological use: Overexpression of this protein to provide quantities adequate for medical use as a topical microbiocide has been attempted in a number of systems including E.coli (Ref.1, Ref.8), Lactobacillus jensenii (Ref.6), the yeast Pichia pastoris (Ref.4) and Nicotiana tabacum (Ref.7); see Ref.9 for a review. One fusion construct for overexpression of this protein can be found in entry AC D1WFZ2. Miscellaneous: Its activity in situ is unknown, however it acts as a viral entry inhibitor, inhibiting HIV-1, HIV-2 and simian immunodeficiency virus (and some other viruses such as feline immunodeficiency virus, measles virus and human herpesvirus) infection and replication. It prevents essential interactions between the envelope glycoprotein and target cell receptors by binding to carbohydrates on viral protein gp120 and possibly by other mechanisms as well. Addition to cells must occur before or shortly after virus addition. It also inhibits cell-to-cell fusion, and virus-to-cell and cell-to-cell transmission of a viral infection. Is remarkably stabile; the protein can withstand multiple freeze-thaw cycles, dissolution in organic solvents, treatment with salt, detergent, H2O2 and boiling without significant loss of anti-HIV activity." No MICs found on DRAMP database Unknown 9210678##9665171 Antimicrob Agents Chemother. 1997 Jul;41(7):1521-1530.##Nat Struct Biol. 1998 Jul;5(7):571-578. "Boyd MR, Gustafson KR, McMahon JB, Shoemaker RH, O'Keefe BR, Mori T, Gulakowski RJ, Wu L, Rivera MI, Laurencot CM, Currens MJ, Cardellina JH 2nd, Buckheit RW Jr, Nara PL, Pannell LK, Sowder RC 2nd, Henderson LE.##Bewley CA, Gustafson KR, Boyd MR, Covell DG, Bax A, Clore GM, Gronenborn AM." "Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.##Solution structure of cyanovirin-N, a potent HIV-inactivating protein." DRAMP00263 GWWNSWGKCVAGTIGGAGTGGLGGAAAGSAVPVIGTGIGGAIGGVSGGLTGAATFC 56 Bacteriocin cerein 7B (Predicted) Q2MDB2 Unknown cer7B Bacillus cereus Antimicrobial Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 16451187 FEMS Microbiol Lett. 2006 Jan;254(1):108-115. "Osc芍riz JC, Cintas L, Holo H, Lasa I, Nes IF, Pisabarro AG." "Purification and sequencing of cerein 7B, a novel bacteriocin produced by Bacillus cereus Bc7." DRAMP00264 EQCREEEDDR 10 Coconut antifungal peptide (Plants) No entry found Unknown Unknown Cocos nucifera "Antifungal, Antiviral" Unknown Unknown Unknown Function: Also has HIV-1 reverse transcriptase activity (IC50=52.5 ?M) "Fungi: Fusarium oxysporum, Mycosphaerella arachidicola (IC50=1.2 ?M), Physalospora piricola." Unknown 16308082 Peptides. 2005 Dec;26(12):2392-2396. "Wang HX, Ng TB." An antifungal peptide from the coconut. DRAMP00265 EALYNSEDLYEETSDSDD 18 Putative antimicrobial protein 1 (Ls-AMP1; Plant defensin) P86895 Unknown Unknown Lippia sidoides (Pepper-rosmarin) Antifungal Unknown Unknown Unknown "Function: May possess antifungal activity. Caution: Antifungal activity was tested using a fraction containing a number of different peptides. It is not clear which peptide actually has antifungal activity." Fungi: Botrytis cinerea. Unknown 21210197 Protein J. 2011 Jan;30(1):32-38. "Moreira JS, Almeida RG, Tavares LS, Santos MO, Viccini LF, Vasconcelos IM, Oliveira JT, Raposo NR, Dias SC, Franco OL." Identification of botryticidal proteins with similarity to NBS-LRR proteins in rosemary pepper (Lippia sidoides Cham.) flowers. DRAMP00266 SPPEAAYGPGNTNSDSGDK 19 Putative antimicrobial protein 2 (Ls-AMP2; Plant defensin) P86896 Unknown Unknown Lippia sidoides (Pepper-rosmarin) Antifungal Unknown Unknown Unknown "Function: May possess antifungal activity. Caution: Antifungal activity was tested using a fraction containing a number of different peptides. It is not clear which peptide actually has antifungal activity." Fungi: Botrytis cinerea. Unknown 21210197 Protein J. 2011 Jan;30(1):32-38. "Moreira JS, Almeida RG, Tavares LS, Santos MO, Viccini LF, Vasconcelos IM, Oliveira JT, Raposo NR, Dias SC, Franco OL." Identification of botryticidal proteins with similarity to NBS-LRR proteins in rosemary pepper (Lippia sidoides Cham.) flowers. DRAMP00267 ESGINLQGDATLANN 15 Antifungal lectin AMML (AMML; Plant defensin) P85004 Unknown Unknown Astragalus mongholicus (Huang qi) (Astragalus membranaceus varmongholicus) Antifungal Unknown Unknown Unknown "Function: Lectin that binds strongly to galactose, lactose, D-raffinose, L-rhamnose and cellobiose, and less strongly to D-glucose, D-xylose and L-arabinose. Does not bind D-galacturonic acid, D-fructose, D-mannose, D-ribose, L-sorbose, maltose and sucrose. Has hemagglutinating activity towards human type O and rabbit erythrocytes. Has strong antifungal activity against B. cinera, and weaker antifungal activity against D. turcia, F. oxysporum and Colletorichum sp. but not against Rhizoctonia solani and Mycosphaerella arachidicola. Miscellaneous: Hemagglutinating activity stable when incubated at 65 degrees Celsius for 30 minutes. Hemagglutinating activity is reduced by 50% when incubated at 75 degrees Celsius for 30 minutes and is abolished by incubation at 85 degrees Celsius for 30 minutes. Hemagglutinating activity is stable between pH 4.5 and 7.5, but is completely inhibited by incubation below pH 3.0 or above pH 10." "Fungi: Botrytis cinerea (IC50=1.2 ?M), Drechslera turcia, Fusarium oxysporum and Colletorichum sp." Galactose and Glucose 16140255 Arch Biochem Biophys. 2005 Oct 1;442(1):72-81. "Yan Q, Jiang Z, Yang S, Deng W, Han L." A novel homodimeric lectin from Astragalus mongholicus with antifungal activity. DRAMP00268 QGIGVGDNDGKRGKR 15 Antifungal protein Pr-2 (Pr-2; Plant defensin) P86796 Unknown Unknown Cucurbita maxima (Pumpkin) (Winter squash) Antifungal Unknown Unknown Unknown "Function: Has strong antifungal activity. Lacks antifungal activity against P.verrucosum var. verrucosum. Lacks antibacterial activity against the Gram-negative bacterium E.coli and against the Gram-positive bacterium S.aureus. Has very low hemolytic activity against human erythrocytes. Increases fungal cell membrane permeability, probably by disrupting the membrane structure." "Fungi: Botrytis cinerea (EC50=20 ?M), Candida albicans (EC50=20 ?M), Colletotrichum coccodes (EC50=10 ?M), Fusarium oxysporum (EC50=10 ?M), Fusarium solani (EC50=10 ?M), Trichoderma harzianum (EC50=20 ?M), Trichoderma viride (EC50=20 ?M), Aspergillus fumigatus EC50=40 ?M), Aspergillus parasiticus (EC50=80 ?M), Didymella bryoniae (EC50=40 ?M)." Unknown 19807165 J Agric Food Chem. 2009 Oct 14;57(19):9299-9304. "Park SC, Kim JY, Lee JK, Hwang I, Cheong H, Nah JW, Hahm KS, Park Y." Antifungal mechanism of a novel antifungal protein from Pumpkin rinds against various fungal pathogens. DRAMP00269 LDSLSFSYNNFEEDD 15 Antifungal protein 1 (GAFP-1; Plant defensin) P86920 Unknown Unknown Arachis hypogaea (Peanut) Antifungal Unknown Unknown Unknown Function: Has strong antifungal activity against fungal phytopathogens. No MICs found on DRAMP database Unknown PubMed ID is not available Submitted (MAY-2011) to UniProtKB Indira S. GAFP-1 from roots of Arachis hypogeae L. DRAMP00270 ATFTIRNNCPYTIWAAAVPGGGRRLNSGGTWTINVAPGTA 40 Osmotin (CpOsm; Plant defensin) P86363 Belongs to the thaumatin family Unknown Calotropis procera (Roostertree) (Asclepias procera) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity. Miscellaneous: On the 2D-gel the determined pI of isoform 1 is: 8.9, its MW is: 22 kDa. On the 2D-gel the determined pI of isoform 2 is: 9.1, its MW is: 22 kDa." "Fungi: Fusarium solani (IC50=67.0 ?g/ml), Colletotrichum gloeosporioides (IC50=32.1 ?g/ml), Neurospora isolate (IC50=57.5 ?g/ml)." Unknown 21334906 Plant Physiol Biochem. 2011 Jul;49(7):738-743. "de Freitas CD, Nogueira FC, Vasconcelos IM, Oliveira JT, Domont GB, Ramos MV." "Osmotin purified from the latex of Calotropis procera: Biochemical characterization, biological activity and role in plant defense." DRAMP00271 ATFTIRNNXPYTVWAAASPGGGRRLDMARIWGRTNXNFD 39 Osmotin-like protein (Thaumatin-like protein; Plant defensin) P83491 Belongs to the thaumatin family Unknown Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis) Antifungal Unknown Unknown Unknown "Function: May be an important antifungal protein. PTM: Contains intrachain disulfide bonds." No MICs found on DRAMP database Unknown PubMed ID is not available Plant Physiol. Biochem. 2001;39:1047-1055. "Subroto T, de Vries H, Schuringa J.J, Soedjanaatmadja U.M.S, Hofsteenge J, Jekel P.A, Beintema J.J." Enzymic and structural studies on processed proteins from the vacuolar (lutoid-body) fraction of latex of Hevea brasiliensis. DRAMP00272 AKITFTNNHPRTIWP 15 Thaumatin-like protein (Plants) P83957 Belongs to the thaumatin family Unknown Castanopsis chinensis (Chinese chinquapin) (Kweilin chestnut) "Antifungal, Antiviral" Unknown Unknown Unknown No comments found on DRAMP database "Fungi: Botrytis cinerea, Fusarium oxysporum (IC50=0.5 ?M), Mycosphaerella arachidicola, Psylla piricola.##HIV-1 reverse transcriptase (IC50=1.6 ?M)." Unknown 12565869 Biochem Biophys Res Commun. 2003 Feb 7;301(2):364-370. "Chu KT, Ng TB." Isolation of a large thaumatin-like antifungal protein from seeds of the Kweilin chestnut Castanopsis chinensis. DRAMP00273 ANFEIVNNCPYTVWAAASPGGGRRLDRGQT 30 Thaumatin-like protein (Plants) P83959 Belongs to the thaumatin family Unknown Phaseolus vulgaris (Kidney bean) (French bean) Antifungal Unknown Unknown Unknown No comments found on DRAMP database "Fungi: Coprinus comatus, Fusarium oxysporum, Pleurotus ostreatus." Unknown 10486265 Biochem Biophys Res Commun. 1999 Sep 16;263(1):130-134. "Ye XY, Wang HX, Ng TB." First chromatographic isolation of an antifungal thaumatin-like protein from French bean legumes and demonstration of its antifungal activity. DRAMP00274 QKIQEIDLQTYLQPQ 15 Amaryllin (Plant defensin) P86781 Unknown Unknown Amaryllis belladonna (Naked lady lily) Antifungal Unknown Unknown Unknown Function: Has antifungal activity. Fungi: Aspergillus flavus and Fusarium oxysporum. Unknown 19478451 Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jun 1;65(Pt 6):635-637. "Kumar S, Singh N, Sinha M, Kaur P, Srinivasan A, Sharma S, Singh TP." "Isolation, purification, crystallization and preliminary crystallographic studies of amaryllin, a plant pathogenesis-related protein from Amaryllis belladonna." DRAMP00276 YSYKKIDCGGACAARCRLSSRPRLCNRACGTCCARCNCVPPGTSGNTETCPCYASLTTHGNKRKCP 66 Snakin-2 (StSN2; Cys-rich; Plant defensin) "Q93X17, A1YN11, Q948Z5" Unknown SN2 Solanum tuberosum (Potato) "Antibacterial, Antifungal" Bridge Unknown Unknown "Function: Has an antimicrobial activity. Causes a rapid aggregation of both Gram-positive and Gram-negative bacteria, but the antimicrobial activity is not correlated with the capacity to aggregate bacteria. Tissue specificity: Expressed in tubers, stems, flowers, shoot apex and leaves, but not in roots or stolons. Induction: Locally up-regulated by abscisic acid, wounding and infection with compatible fungus. Down-regulated by gibberellic acid or infection with virulent bacteria. No responses to ethylene or abiotic stresses. PTM: Six disulfide bonds may be present." "Gram-positive bacteria: Clavibacter michiganensis (EC50=4 ?M), Ralstonia solanacearum (EC50=15 ?M).##Fungi: pathogens Rhizobium meliloti (EC50=8 ?M), Botrytis cinerea (EC50=2 ?M), Fusarium solani (EC50=2 ?M), Fusarium culmorum (EC50=2 ?M), Fusarium oxysporum f.sp. conglutinans (EC50=10 ?M), Fusarium oxysporum f.sp.lycopersici (EC50=20 ?M), Plectosphaerella cucumerina (EC50=10 ?M), Colletotrichum graminicola (EC50=10 ?M), Colletotrichum lagenarium (EC50=10 ?M), Bipolaris maydis (EC50=20 ?M), Aspergillus flavus (EC50=20 ?M)." Unknown 11891250 Plant Physiol. 2002 Mar;128(3):951-961. "Berrocal-Lobo M, Segura A, Moreno M, L??pez G, Garc??a-Olmedo F, Molina A." "Snakin-2, an antimicrobial peptide from potato whose gene is locally induced by wounding and responds to pathogen infection." DRAMP00277 DICTNCCAGTKGCNTTSANGAFICEGQSDPKKPKACPLNCDPHIAYA 47 Potamin-1 (PT-1; Plants) P84813 Belongs to the protease inhibitor I20 Unknown Solanum tuberosum (Potato) "Antifungal, Antibacterial" Unknown Unknown Unknown "Function: Inhibitor of serine proteases chymotrypsin, papain and trypsin. Has strong antifungal activity against C. albicans and R.solani. Has antibacterial activity against the Gram-positive bacterium C.michiganense, but lacks antibacterial activity against the Gram-positive bacterium S. aureus. Lacks hemolytic activity against human erythrocytes. PTM: Contains four disulfide bonds (By similarity)." Fungi: Candida albicans and Rhizoctonia solani.##Gram-positive bacterium: Clavibacter michiganensis. Unknown 15809084 Biochem Biophys Res Commun. 2005 May 13;330(3):921-927. "Kim JY, Park SC, Kim MH, Lim HT, Park Y, Hahm KS." Antimicrobial activity studies on a trypsin-chymotrypsin protease inhibitor obtained from potato. DRAMP00278 LPSDATLVLDQTGKELDARL 20 Antifungal protein J (AFP-J; Plants) P84794 Belongs to the protease inhibitor I3 Unknown Solanum tuberosum (Potato) Antifungal Unknown Unknown Unknown "Function: Inhibitor of serine proteases chymotrypsin, pepsin and trypsin. Has strong antifungal activity. Lacks hemolytic activity against human erythrocytes." "Fungi: Candida albicans TIMM 1768, Saccharomyces cerevisiae KCTC 7296, Trichosporon beigelii KCTC 7707." Unknown 16076139 J Agric Food Chem. 2005 Aug 10;53(16):6491-6496. "Park Y, Choi BH, Kwak JS, Kang CW, Lim HT, Cheong HS, Hahm KS." Kunitz-type serine protease inhibitor from potato (Solanum tuberosum L. cv. Jopung). DRAMP00279 AQIVKLGGDDGSLAFVPSKISVAAGEAIEFVNNAGFPHNIVFDEDAVPAGVDADAISYDDYLNSKGETVVRKLSTPGVYGVYCEPHAGAGMKMTITVQ 98 Plastocyanin (Plants) P56274 Unknown PETE Ulva pertusa (Sea lettuce) Antiviral Combine helix and strand structure Unknown 1IUZ resolved by X-ray. "Function: Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I. Has antiviral activity against Potato virus Y (strain N). Domain: Contains 1 plastocyanin-like domain." No MICs found on DRAMP database Unknown 9933621##PubMed ID is not availbale J Biol Chem. 1999 Feb 12;274(7):4225-4230.##Submitted (JUN-2003) to UniProtKB. "Shibata N, Inoue T, Nagano C, Nishio N, Kohzuma T, Onodera K, Yoshizaki F, Sugimura Y, Kai Y.##" Novel insight into the copper-ligand geometry in the crystal structure of Ulva pertusa plastocyanin at 1.6-A resolution. Structural basis for regulation of the copper site by residue 88.## DRAMP00280 LIYAKVECLTTGVRTYVGKQSWPELVGTKGKTAAATIDKENTHVTAVLCPPLTTLAACRTFDFRCDRVRVLINRIGGVVTKTPTVG 86 Trypsin inhibitor (FtTI; Plant defensin) P86971 Unknown Unknown Fagopyrum tataricum (Tartarian buckwheat) (Polygonum tataricum) Antifungal Unknown Unknown Unknown "Function: Serine protease inhibitor which is active against trypsin. Displays strong antifungal activity against a number of phytopathogenic fungi. Biophysicochemical properties: pH dependence (Optimum pH is 8.0 at 37 degrees Celsius. Maintains over 90% of its inhibitory activity from pH 3 to 10); Temperature dependence (Active between 10 and 60 degrees Celsius. 84% activity retained when heated for 30 minutes at 80 degrees Celsius. Incubation at temperatures above 80 degrees Celsius rapidly decreases inhibitory activity). PTM: Contains two disulfide bonds 8-65; 49-58." "Fungi: M. melonis, A. cucumerina, A. solani, C. glaeosporioides and P. capsici." Unknown 21544554 Appl Biochem Biotechnol. 2011 May 5. "Ruan JJ, Zhou ML, Chen H, Shao JR." Identification and Characterization of a Trypsin Inhibitor from Fagopyrum tataricum Seeds. DRAMP00281 NTCENLAGSYKGVCFGGCDRHCRTQEGAISGRCRDDFRCWCTKNC 45 Defensin-like protein 230 (Disease resistance response protein 230; Plant defensin) Q01783 Belongs to the DEFL family PI230 Pisum sativum (Garden pea) unknow Unknown Unknown Unknown "Function: Has antifungal activity (By similarity). Induction: Upon contact with the plant pathogen fungus Fusarium solani. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 1799696 Mol Plant Microbe Interact. 1991 Jul-Aug;4(4):324-331. "Chiang CC, Hadwiger LA." The Fusarium solani-induced expression of a pea gene family encoding high cysteine content proteins. DRAMP00282 GPMRIAEARHCESLSHRFKGPCTRDSNCASVCETERFSGGNCHGFRRRCFCTKPC 55 Defensin-like protein P322 (Probable protease inhibitor P322; Plant defensin) P20346 Belongs to the DEFL family Unknown Solanum tuberosum (Potato) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown PubMed ID is not available "Plant Molecular Biology. 1988, 11(3):255-269." "Stiekema WJ, Heidekamp F, Dirkse WG, van Beckum J, de Haan P, ten Bosch C, Louwerse JD." Molecular cloning and analysis of four potato tuber mRNAs. DRAMP00283 RECQSQSHRYKGACVHDTNCASVCQTEGFSGGKCVGFRGRCFCTKAC 47 Defensin Ec-AMP-D1 (Plant defensin) P86518 Belongs to the DEFL family Unknown Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity. Inhibits hyphal development in P. infestans (IC50=25.5 ?g/ml), but not release of zoospores. At concentrations above 100 ?g/ml, induces morphological changes such as lysis of hyphae and sporangia in P. infestans. PTM: Contains four disulfide bonds (By similarity)." "Fungi: Fusarium graminearum (IC50=15 ?g/ml), Fusarium oxysporum (IC50=102 ?g/ml), F. verticillioides (IC50=8.5 ?g/ml), Diplodia maydis (IC50=12.5 ?g/ml)." Unknown 18625284 Biochimie. 2008 Nov-Dec;90(11-12):1667-1673. "Odintsova TI, Rogozhin EA, Baranov Y, Musolyamov AKh, Yalpani N, Egorov TA, Grishin EV." Seed defensins of barnyard grass Echinochloa crusgalli (L.) Beauv. DRAMP00284 RVCMGKSQHHSFPCISDRLCSNECVKEEGGWTAGYCHLRYCRCQKAC 47 Defensin-like protein 1 (SI alpha-1; Plant defensin) P21923 Belongs to the DEFL family Unknown Sorghum bicolor (Sorghum) (Sorghum vulgare) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity (By similarity). PTM: Contains four disulfide bonds 3-47; 14-36; 20-41; 24-43." No MICs found on DRAMP database Unknown 1995329##7705336 FEBS Lett. 1991 Feb 11;279(1):101-104.##Eur J Biochem. 1995 Mar 1;228(2):250-256. "Bloch C Jr, Richardson M.##Nitti G, Orr迄 S, Bloch C Jr, Morhy L, Marino G, Pucci P." A new family of small (5 kDa) protein inhibitors of insect alpha-amylases from seeds or sorghum (Sorghum bicolar (L) Moench) have sequence homologies with wheat gamma-purothionins.##Amino acid sequence and disulphide-bridge pattern of three gamma-thionins from Sorghum bicolor. DRAMP00285 RVCMGKSAGFKGLCMRDQNCAQVCLQEGWGGGNCDGVMRQCKCIRQCW 48 Defensin-like protein 2 (SI alpha-2; Plant defensin) P21924 Belongs to the DEFL family Unknown Sorghum bicolor (Sorghum) (Sorghum vulgare) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity (By similarity). PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 1995329 FEBS Lett. 1991 Feb 11;279(1):101-104. "Bloch C Jr, Richardson M." A new family of small (5 kDa) protein inhibitors of insect alpha-amylases from seeds or sorghum (Sorghum bicolar (L) Moench) have sequence homologies with wheat gamma-purothionins. DRAMP00286 RVCRRRSAGFKGLCMSDHNCAQVCLQEGWGGGNCDGVIRQCKCIRQC 47 Defensin-like protein 3 (SI alpha-3; Plant defensin) P21925 Belongs to the DEFL family Unknown Sorghum bicolor (Sorghum) (Sorghum vulgare) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity (By similarity). PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43." No MICs found on DRAMP database Unknown 1995329##7705336 FEBS Lett. 1991 Feb 11;279(1):101-104.##Eur J Biochem. 1995 Mar 1;228(2):250-256. "Bloch C Jr, Richardson M.##Nitti G, Orr迄 S, Bloch C Jr, Morhy L, Marino G, Pucci P." A new family of small (5 kDa) protein inhibitors of insect alpha-amylases from seeds or sorghum (Sorghum bicolar (L) Moench) have sequence homologies with wheat gamma-purothionins.##Amino acid sequence and disulphide-bridge pattern of three gamma-thionins from Sorghum bicolor. DRAMP00287 RVCRRRSAGFKGLCMSDHNCAQVCLQEGWGGGNCDGVMRQCKCIRQC 47 Defensin-like protein 21 (SI alpha-2.1; Plant defensin) Q09198 Belongs to the DEFL family Unknown Sorghum bicolor (Sorghum) (Sorghum vulgare) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity (By similarity). PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43." No MICs found on DRAMP database Unknown 7705336 Eur J Biochem. 1995 Mar 1;228(2):250-256. "Nitti G, Orr迄 S, Bloch C Jr, Morhy L, Marino G, Pucci P." Amino acid sequence and disulphide-bridge pattern of three gamma-thionins from Sorghum bicolor. DRAMP00288 RECQSQSHRYKGACVHDTNCASVCQTEGFSGGKCVGFRGRCFCTKHC 47 Defensin Ec-AMP-D2 (Plant defensin) P86519 Belongs to the DEFL family Unknown Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity. Inhibits spore germination in Fusarium oxysporum (IC(50)=102 ??g/ml). Inhibits hyphal development in P. infestans (IC(50)=50 ??g/ml). Does not induce morphological changes such as lysis of hyphae and sporangia in P. infestans. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 18625284 Biochimie. 2008 Nov-Dec;90(11-12):1667-1673. "Odintsova TI, Rogozhin EA, Baranov Y, Musolyamov AKh, Yalpani N, Egorov TA, Grishin EV." Seed defensins of barnyard grass Echinochloa crusgalli (L.) Beauv. DRAMP00289 RLCRVRGTRGHCFNDHGCDKVCTREGFVRGKCNGILRRCICDRQC 45 Defensin-like protein (Gamma-thionin; Plant defensin) B5LZ79 Belongs to the DEFL family Unknown Gymnadenia conopsea (Fragrant orchid) (Orchis conopsea) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity (By similarity). PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown PubMed ID is not available##PubMed ID is not available Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.##Submitted (JUL-2008) to UniProtKB. "Unknown##Mukherjee G, Sen SK." "Unknown##Purification, characterization, and antifungal activity of chitinase from Streptomyces venezuelae P(10)." DRAMP00290 KTCENLSDSFKGPCIPDGNCNKHCKEKEHLLSGRCRDDFRCWCTRNC 47 Defensin Lc-def (Plant defensin) "B3F051, P85530" Belongs to the DEFL family Unknown Lens culinaris subsp. culinaris (Cultivated lentil) (Lens esculenta) Antifungal Combine helix and strand structure Unknown 2LJ7 resolved by NMR. "Function: Has antifungal activity against the phytopathogenic fungus Aspergillus niger VKM F-2259, but not against A.alternatia VKM F- 3047. Does not inhibit trypsin or chymotrypsin. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 18468512##PubMed ID is not available Biochem Biophys Res Commun. 2008 Jul 11;371(4):860-865.##To be Published. "Finkina EI, Shramova EI, Tagaev AA, Ovchinnikova TV.##Shenkarev Z, Mineev K, Gizatullina A, Finkina E, Arseniev A, Ovchinnikova T." A novel defensin from the lentil Lens culinaris seeds.##Solution structure of defensin Lc-def from germinated lentil (Lens Culinaris) seeds. DRAMP00291 RTCESQSHRFKGACLSDTNCASVCQTEGFPAGDCKGARRRCFCVKPC 47 Defensin-like protein (Gamma-thionin homolog; Plant defensin) A3FPF2 Belongs to the DEFL family Unknown Nelumbo nucifera (Sacred lotus) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity (By similarity). PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown PubMed ID is not available##16972135 Submitted (FEB-2007) to the EMBL/GenBank/DDBJ database##Curr Microbiol. 2006 Oct;53(4):265-269. "Unknown##Mukherjee G, Sen SK." "Unknown##Purification, characterization, and antifungal activity of chitinase from Streptomyces venezuelae P(10)." DRAMP00292 RVCESQSHGFHGLCNRDHNCALVCRNEGFSGGRCKRSRRCFCTRIC 46 Defensin-like protein (8.4 kDa sulfur-rich protein; Plant defensin) Q07502 Belongs to the DEFL family Unknown Glycine max (Soybean) (Glycine hispida) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity (By similarity). PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 8278516 Plant Physiol. 1993 Feb;101(2):699-700. "Choi Y, Choi YD, Lee JS." Nucleotide sequence of a cDNA encoding a low molecular weight sulfur-rich protein in soybean seeds. DRAMP00293 RICRRRSAGFKGPCVSNKNCAQVCMQEGWGGGNCDGPLRRCKCMRRC 47 Gamma1-hordothionin (Gamma 1-H; Plant defensin) P20230 Belongs to the DEFL family Unknown Hordeum vulgare (Barley) Antifungal Combine helix and strand structure "Gamma 1-H adopts a well-defined triple-stranded antiparallel beta-sheet (residues 1-6, 31-34, and 39-47), an alpha-helix (residues 16-28), and the corresponding connecting loops. Three disulfide bridges are located in the hydrophobic core holding together the alpha-helix and the beta-sheet and forming a cysteine-stabilized alpha-helical (CSH) motif." 1GPT resolved by NMR. "Function: Inhibits protein translation in cell-free systems. PTM: Contains four disulfide bonds 3-47; 14-34; 20-21; 24-43. Caution: Was initially thought to be a thionin." No MICs found on DRAMP database Unknown 2176600##8380707 Eur I Biochem 1990;194:533-539.##Biochemistry. 1993 Jan 19;32(2):715-724. "Mendez E, Moreno A, Colilla F.J, Pelaez F, Limas G.G, Mendez R, Soriano F, Salinas M, de Haro C.##Bruix M, Jim??nez MA, Santoro J, Gonz??lez C, Colilla FJ, M??ndez E, Rico M." "Primary structure and inhibition of protein synthesis in eukaryotic cell-free system of a novel thionin, gamma-hordothionin, from barley endosperm.##Solution structure of gamma 1-H and gamma 1-P thionins from barley and wheat endosperm determined by 1H-NMR: a structural motif common to toxic arthropod proteins." DRAMP00294 YKRGGGGWGGGGGWKGGGGGGGGWKGGGGGGKGGGG 36 Glycine-rich protein GWK (Plants) P84064 Unknown Unknown Cucumis melo (Muskmelon) Antifungal Unknown Unknown Unknown Function: Possesses antifungal activity against a number of phytopathogenic fungi. Fungi: Hordeum sativum and F. culmorum. Unknown PubMed ID is not available Submitted (AUG-2004) to UniProtKB "Vassilevski AA, Egorov TA, Grishin EV." unknow DRAMP00295 ADPTFGFTPLGLSEKANLQIMKAYD 25 Soybean toxin 27 kDa chain (SBTX 27 kDa chain; Plant defensin) P86520 Unknown Unknown Glycine max (Soybean) (Glycine hispida) Antifungal Unknown Unknown Unknown "Function: Involved in plant defense. Has antifungal activity against C. sojina but not A. niger and F. solani. Does not have urease or hemagglutination activities. Does not inhibit trypsin. Injection into mice produces toxic effects such as dyspnea, tonic-clonic convulsion and death. Subunit structure Heterodimer of a 27 kDa subunit and a 17 kDa subunit; disulfide-linked. Tissue specificity: Expressed in seeds, leaves, roots and stem (at protein level). Induction: In seeds, induced by jasmonate. Post-translational modification: SBTX is known to be glycosylated but it is not known which one of its two subunits is modified; contains 5% carbohydrates. Toxic dose: LD50 is 5.6 mg/kg by intraperitoneal injection into mice. Miscellaneous: On the 2D-gel the determined pI of SBTX is: 8.2, its MW is: 44 kDa. Biophysicochemical properties: pH dependence (Activity decreases below pH 5.5 and above pH 8.0)." Fungi: C. sojina. Unknown 18328522 Toxicon. 2008 May;51(6):952-963. "Vasconcelos IM, Morais JK, Siebra EA, Carlini CR, Sousa DO, Beltramini LM, Melo VM, Oliveira JT." "SBTX, a new toxic protein distinct from soyatoxin and other toxic soybean [Glycine max] proteins, and its inhibitory effect on Cercospora sojina growth." DRAMP00296 PNPKVFFDMTIGGQSAGRIVMEEYA 25 Soybean toxin 17 kDa chain (SBTX 17 kDa chain; Plant defensin) P86548 Unknown Unknown Glycine max (Soybean) (Glycine hispida) "Antifungal, Cytotoxic" Unknown Unknown Unknown "Function: Involved in plant defense. Has antifungal activity against C.sojina but not A.niger and F.solani. Does not have urease or hemagglutination activities. Does not inhibit trypsin. Injection into mice produces toxic effects such as dyspnea, tonic-clonic convulsion and death. Subunit structure: Heterodimer of a 27 kDa subunit and a 17 kDa subunit; disulfide-linked. Tissue specificity: Expressed in seeds, leaves, roots and stem (at protein level). Induction: In seeds, induced by jasmonate. Post-translational modification: SBTX is known to be glycosylated but it is not known which one of its two subunits is modified; contains 5% carbohydrates. Toxic dose: LD50 is 5.6 mg/kg by intraperitoneal injection into mice. Miscellaneous: On the 2D-gel the determined pI of SBTX is: 8.2, its MW is: 44 kDa. Biophysicochemical properties: pH dependence (Activity decreases below pH 5.5 and above pH 8.0). " No MICs found on DRAMP database Unknown 18328522 Toxicon. 2008 May;51(6):952-963. "Vasconcelos IM, Morais JK, Siebra EA, Carlini CR, Sousa DO, Beltramini LM, Melo VM, Oliveira JT." "SBTX, a new toxic protein distinct from soyatoxin and other toxic soybean [Glycine max] proteins, and its inhibitory effect on Cercospora sojina growth." DRAMP00297 ACGILHDNCVYVPAQNPCCRGLQCRYGKCLVQV 33 U1-theraphotoxin-Pc1a (U1-TRTX-Pc1a; Psalmopeotoxin-1; PcFK1; Plants) P0C201 Unknown Unknown Psalmopoeus cambridgei (Trinidad chevron tarantula) "Antiplasmodial, Cytotoxic" Combine helix and strand structure Unknown 1X5V resolved by NMR. "Function: Possess strong antiplasmodial activity against the intra-erythrocyte stage of Plasmodium falciparum in vitro. Interacts with infected and healthy erythrocytes. Does not lyse erythrocytes, is not cytotoxic to nucleated mammalian cells, and does not inhibit neuromuscular function. Has neither antibacterial nor antifungal activity. Tissue specificity: Expressed by the venom gland. Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. PTM: Contains three disulfide bonds and C-terminal amidation." Plasmodium falciparum (IC50=1.59 ?M). Unknown 15304333##16452619 FEBS Lett. 2004 Aug 13;572(1-3):109-117.##Protein Sci. 2006 Mar;15(3):628-634. "Choi SJ, Parent R, Guillaume C, Deregnaucourt C, Delarbre C, Ojcius DM, Montagne JJ, C??l??rier ML, Phelipot A, Amiche M, Molgo J, Camadro JM, Guette C.##Pimentel C, Choi SJ, Chagot B, Guette C, Camadro JM, Darbon H." "Isolation and characterization of Psalmopeotoxin I and II: two novel antimalarial peptides from the venom of the tarantula Psalmopoeus cambridgei.##Solution structure of PcFK1, a spider peptide active against Plasmodium falciparum." DRAMP00298 RCLPAGKTCVRGPMRVPCCGSCSQNKCT 28 U1-theraphotoxin-Pc1a (U2-TRTX-Pc1a; Psalmopeotoxin-2; PcFK2; Plants) P0C202 Unknown Unknown Psalmopoeus cambridgei (Trinidad chevron tarantula) "Antiplasmodial, Cytotoxic" Unknown Unknown Unknown "Function: Possess strong antiplasmodial activity against the intra-erythrocyte stage of P.falciparum in vitro. Specifically interacts with infected erythrocytes. Does not lyse erythrocytes, is not cytotoxic to nucleated mammalian cells, and does not inhibit neuromuscular function. Has neither antibacterial nor antifungal activity. Tissue specificity: Expressed by the venom gland. Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin By similarity. Miscellaneous: Usually endopeptidases cleave the propeptide at the C-terminus of the basic doublet (Arg-37-38-Arg), but here, it seems that the endopeptidase cleaves the precursor within the doublet. PTM: Contains three disulfide bonds (By similarity)." Plasmodium falciparum (IC50=1.15 ?M). Unknown 15304333 FEBS Lett. 2004 Aug 13;572(1-3):109-117. "Choi SJ, Parent R, Guillaume C, Deregnaucourt C, Delarbre C, Ojcius DM, Montagne JJ, C??l??rier ML, Phelipot A, Amiche M, Molgo J, Camadro JM, Guette C." Isolation and characterization of Psalmopeotoxin I and II: two novel antimalarial peptides from the venom of the tarantula Psalmopoeus cambridgei. DRAMP00299 DADIAVWAPPVNAQN 15 Ribonuclease (Plants) P84784 Unknown Unknown Thelephora ganbajun (Mushroom) Antiviral Unknown Unknown Unknown "Function: Inhibits HIV-1 reverse transcriptase. Miscellaneous: Inhibits HIV-1 reverse transcriptase with an IC50 of 300 nM. Biophysicochemical properties: pH dependence (Optimum pH is 6-7); Temperature dependence (Optimum temperature is 45 degrees Celsius. Activity decreases sharply above 50 degrees Celsius and below 40 degrees Celsius)." No MICs found on DRAMP database Unknown 15474506 Biochem Biophys Res Commun. 2004 Nov 12;324(2):855-859. "Wang HX, Ng TB." Purification of a novel ribonuclease from dried fruiting bodies of the edible wild mushroom Thelephora ganbajun. DRAMP00300 PGAGSQEERMQGQMEGQDFSHEERFLSMVRE 31 Antifungal protein 1 (Pa-AFP1; Plant defensin) B3EWF0 Unknown Unknown Passiflora alata (Winged-stem passion flower) (Fragrant granadilla) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity against C. gloeosporioides but not against Botrytis cinerea and Fusarium sp. or against various yeasts. Has no antibacterial activity. Subunit structure: Heterodimer; disulfide-linked. PTM: Disulfide bonds." No MICs found on DRAMP database Unknown 20955745 Peptides. 2011 May;32(5):868-874. "Ribeiro SM, Almeida RG, Pereira CA, Moreira JS, Pinto MF, Oliveira AC, Vasconcelos IM, Oliveira JT, Santos MO, Dias SC, Franco OL." Identification of a Passiflora alata Curtis dimeric peptide showing identity with 2S albumins. DRAMP00301 DYPKLTFTTS 10 Malanin chain A (Plant defensin) P86600 Unknown Unknown Malania oleifera "Anticancer, Cytotoxic" Unknown Unknown Unknown "Function: Significantly inhibits growth and induces an apoptotic response in HeLa cells through cell-cycle arrest at S-phase. Exhibits highly cytotoxic activities against cancer cell and non-cancer cell lines. Subunit structure: Heterodimer of an A chain and a B chain, which are crosslinked by one or more disulfide bonds. Toxic dose: LD50 values are 26.22 ?g/kg by intraperitoneal injection and 43.11 mg/kg by intragingival injection into IRC strain mice." "Cancer cell lines: HeLa (IC50=0.15㊣0.08 nM), PC-12 (IC50=7.71㊣0.24 nM), MCF-7 (IC50=11.20㊣0.02 nM), K562 (IC50=15.80㊣0.09 nM).##Non-cancer cell lines: Vero (IC50=2.79㊣0.05 nM) and Madin-Darby canine kidney cells (IC50=3.92㊣0.01 nM)." Unknown 19341757 Toxicon. 2009 Aug;54(2):121-127. "Yuan Y, Dai X, Wang D, Zeng X." "Purification, characterization and cytotoxicity of malanin, a novel plant toxin from the seeds of Malania oleifera." DRAMP00302 DETXTDEEFN 10 Malanin chain B (Plant defensin) P86601 Unknown Unknown Malania oleifera "Anticancer, Cytotoxic" Unknown Unknown Unknown "Function: Significantly inhibits growth and induces an apoptotic response in HeLa cells through cell-cycle arrest at S-phase. Exhibits highly cytotoxic activities against cancer cell and non-cancer cell lines. Subunit structure: Heterodimer of an A chain and a B chain, which are crosslinked by one or more disulfide bonds. Toxic dose: LD50 values are 26.22 ?g/kg by intraperitoneal injection and 43.11 mg/kg by intragingival injection into IRC strain mice." "Cancer cell lines: HeLa (IC50=0.15㊣0.08 nM), PC-12 (IC50=7.71㊣0.24 nM), MCF-7 (IC50=11.20㊣0.02 nM), K562 (IC50=15.80㊣0.09 nM).##Non-cancer cell lines: Vero (IC50=2.79㊣0.05 nM) and Madin-Darby canine kidney cells (IC50=3.92㊣0.01 nM)." Unknown 19341757 Toxicon. 2009 Aug;54(2):121-127. "Yuan Y, Dai X, Wang D, Zeng X." "Purification, characterization and cytotoxicity of malanin, a novel plant toxin from the seeds of Malania oleifera." DRAMP00303 ACGGGGGDVGSLISASLFDQMLKYRNDPRCCXXGF 35 Basic endochitinase CH1 (Plant defensin) P29137 Belongs to the glycosyl hydrolase 19 family (Chitinase class I subfamily) Unknown Castanea sativa (Sweet chestnut) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins." No MICs found on DRAMP database Unknown 16653058 Plant Physiol. 1992 Oct;100(2):778-783. "Collada C, Casado R, Fraile A, Aragoncillo C." Basic Endochitinases Are Major Proteins in Castanea sativa Cotyledons. DRAMP00304 SIGFDGLNDPDIVAR 15 Endochitinase 1 (Plant defensin) P86078 Belongs to the glycosyl hydrolase 20 family (Chitinase class I subfamily) Unknown Capsicum annuum var. annuum (Red pepper) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins." No MICs found on DRAMP database Unknown PubMed ID is not availbale Submitted (JUL-2008) to UniProtKB "Belchi-Navarro S, Almagro L, Pedreno M.A." Unknown DRAMP00305 NNFYSYNAFITAAKSFPGFGTTGDTAVRGPIQISYNYNYGPCGR 44 Endochitinase 1 (Plant defensin) P86081 Belongs to the glycosyl hydrolase 21 family (Chitinase class I subfamily) Unknown Capsicum chinense (Scotch bonnet) (Bonnet pepper) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins." No MICs found on DRAMP database Unknown PubMed ID is not availbale Submitted (JUL-2008) to UniProtKB "Gomez Ros L.V, Almagro L, Ros Barcelo A, Pedreno M.A." Unknown DRAMP00306 GPLQLSWNYNYGAAGK 16 Endochitinase 1 (Plant defensin) P85343 Belongs to the glycosyl hydrolase 22 family (Chitinase class I subfamily) Unknown Ginkgo biloba (Ginkgo) (Maidenhair tree) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins." No MICs found on DRAMP database Unknown 19157640 J Plant Physiol. 2009 May 15;166(8):831-843. "Uzal EN, G車mez-Ros LV, Hern芍ndez JA, Pedre?o MA, Cuello J, Ros Barcel車 A." Analysis of the soluble cell wall proteome of gymnosperms. DRAMP00307 EQCGNQAGGXVPPNG 15 Endochitinase A1 (Plant defensin) P21225 Belongs to the glycosyl hydrolase 23 family (Chitinase class I subfamily) Unknown Pisum sativum (Garden pea) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Induction: By infection with the fungal pathogen Ascochyta pisi." No MICs found on DRAMP database Unknown PubMed ID is not availbale Planta 184:24-29(1991). "Vad K, Mikkelsen JD, Collinge DB." "Induction, purification and characterization of chitinase isolated from pea leaves inoculated with Ascochyta pisi." DRAMP00308 AIGFDGLNDPDIVAR 15 Endochitinase 1 (Plant defensin) P85337 Belongs to the glycosyl hydrolase 24 family (Chitinase class I subfamily) Unknown Taxus baccata (English yew) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins." No MICs found on DRAMP database Unknown 19157640 J Plant Physiol. 2009 May 15;166(8):831-843. "Uzal EN, G車mez-Ros LV, Hern芍ndez JA, Pedre?o MA, Cuello J, Ros Barcel車 A." Analysis of the soluble cell wall proteome of gymnosperms. DRAMP00309 MTEQKPKPSCHNVMVGNYVPTASDRAANRTLGFGLVTNIINGGLDC 46 Endochitinase 2 (CHIT 2; Plant defensin) Q06014 Belongs to the glycosyl hydrolase 25 family (Chitinase class I subfamily) Unknown Arachis hypogaea (Peanut) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal and bacterial pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Induction: By glucan and Phytophthora megasperma elicitors." No MICs found on DRAMP database Unknown 1980004 Mol Gen Genet. 1990 Dec;224(3):469-476. "Herget T, Schell J, Schreier PH." Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea. DRAMP00310 SAIWFWMTPQSPK 13 Endochitinase 2 (Plant defensin) P86079 Belongs to the glycosyl hydrolase 26 family (Chitinase class I subfamily) Unknown Capsicum annuum var. annuum (Red pepper) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins." No MICs found on DRAMP database Unknown PubMed ID is not availbale Submitted (JUL-2008) to UniProtKB "Gomez Ros L.V, Almagro L, Ros Barcelo A, Pedreno M.A." Unknown DRAMP00311 GPIQISYNYNYGPCGRYCGILGVSPGDNLDCGNQR 35 Endochitinase 2 (Plant defensin) P86082 Belongs to the glycosyl hydrolase 27 family (Chitinase class I subfamily) Unknown Capsicum chinense (Scotch bonnet) (Bonnet pepper) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins." No MICs found on DRAMP database Unknown PubMed ID is not availbale Submitted (JUL-2008) to UniProtKB "Sabater Jara A.B, Almagro L, Pedreno M.A." Unknown DRAMP00312 TAGFGVFTNIINGGLECGK 19 Endochitinase 2 (Plant defensin) P85338 Belongs to the glycosyl hydrolase 28 family (Chitinase class I subfamily) Unknown Taxus baccata (English yew) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. PTM: Contians one disulfide bond (By similarity)." No MICs found on DRAMP database Unknown 19157640 J Plant Physiol. 2009 May 15;166(8):831-843. "Uzal EN, G車mez-Ros LV, Hern芍ndez JA, Pedre?o MA, Cuello J, Ros Barcel車 A." Analysis of the soluble cell wall proteome of gymnosperms. DRAMP00313 MTPQGNKPSSHDVITGRWTPSDADRAAGRVSGFGVITNIINGGLDC 46 Endochitinase 3 (CHIT 3; Plant defensin) Q06015 Belongs to the glycosyl hydrolase 29 family (Chitinase class I subfamily) Unknown Arachis hypogaea (Peanut) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Defense against chitin containing fungal and bacterial pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Induction: Constitutively expressed at low levels." No MICs found on DRAMP database Chitin-binding 1980004 Mol Gen Genet. 1990 Dec;224(3):469-476. "Herget T, Schell J, Schreier PH." Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea. DRAMP00314 MYDESTGYSSALK 13 Endochitinase 3 (Plant defensin) P85355 Belongs to the glycosyl hydrolase 30 family (Chitinase class I subfamily) Unknown Taxus baccata (English yew) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins." No MICs found on DRAMP database Unknown 19157640 J Plant Physiol. 2009 May 15;166(8):831-843. "Uzal EN, G車mez-Ros LV, Hern芍ndez JA, Pedre?o MA, Cuello J, Ros Barcel車 A." Analysis of the soluble cell wall proteome of gymnosperms. DRAMP00315 MTPQGNKPSCHDVITNAWRPTATDSAAGRAPGYGVITNIINGGLDC 46 Endochitinase 4 (CHIT 4; Plant defensin) Q06016 Belongs to the glycosyl hydrolase 31 family (Chitinase class I subfamily) Unknown Arachis hypogaea (Peanut) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Defense against chitin containing fungal and bacterial pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Induction: By glucan elicitor, and to a lesser extent by yeast extract, Phytophthora megasperma elicitor, UV light and dilution." No MICs found on DRAMP database Chitin-binding 1980004 Mol Gen Genet. 1990 Dec;224(3):469-476. "Herget T, Schell J, Schreier PH." Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea. DRAMP00316 MTAQGNKPSSHDVITGRWTPSAADRAAGRVSGFGVITNIINGGLDC 46 Endochitinase 1A (CHIT 1A; Plant defensin) Q06012 Belongs to the glycosyl hydrolase 32 family (Chitinase class I subfamily) Unknown Arachis hypogaea (Peanut) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Defense against chitin containing fungal and bacterial pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Induction: By yeast extract and dilution. Slight induction by glucan elicitor." No MICs found on DRAMP database Chitin-binding 1980004 Mol Gen Genet. 1990 Dec;224(3):469-476. "Herget T, Schell J, Schreier PH." Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea. DRAMP00317 MTAQGNKPSSHDVITGRWTPSAADKAAGRVSGFGVITNIINGGLDC 46 Endochitinase 1B (CHIT 1B; Plant defensin) Q06013 Belongs to the glycosyl hydrolase 33 family (Chitinase class I subfamily) Unknown Arachis hypogaea (Peanut) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Defense against chitin containing fungal and bacterial pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Induction: By yeast extract and dilution. Slight induction by glucan elicitor." No MICs found on DRAMP database Chitin-binding 1980004 Mol Gen Genet. 1990 Dec;224(3):469-476. "Herget T, Schell J, Schreier PH." Elicitor-specific induction of one member of the chitinase gene family in Arachis hypogaea. DRAMP00318 EQCGRQAGGATCPNNLCCSQYGY 23 Endochitinase B (Plant defensin) P21227 Belongs to the glycosyl hydrolase 34 family (Chitinase class I subfamily) Unknown Pisum sativum (Garden pea) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Induction: By infection with the fungal pathogen Ascochyta pisi." No MICs found on DRAMP database Chitin-binding PubMed ID is not availbale Planta 184:24-29(1991). "Vad K, Mikkelsen JD, Collinge DB." "Induction, purification and characterization of chitinase isolated from pea leaves inoculated with Ascochyta pisi." DRAMP00319 ENCGRQAG 8 Endochitinase (Plant defensin) P86473 Belongs to the glycosyl hydrolase 35 family (Chitinase class I subfamily) Unknown Actinidia chinensis (Kiwi) (Yangtao) Antifungal Unknown Unknown Unknown "Function: Defense against chitin containing fungal pathogens (By similarity). Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Allergenic properties: Causes an allergic reaction in human. Domian: Contains 1 chitin-binding type-1 domain." No MICs found on DRAMP database IgE 1553642 Tidsskr Nor Laegeforen. 1992 Jan 10;112(1):38-42. Rygnestad T. Suicide in Norway. Changes in the 20th century with special emphasis on the development during the last 20 years. DRAMP00320 MARVNSLKCALCFIVLILFVQLNCIPETRVMAVELSRVFLQTSSTDCGEPCVYIPCTITALLGCSCLNKVCVRP 74 Acyclotide phyb-K (Plant defensin) B3EWH6 Belongs to the cyclotide family (Bracelet subfamily) Unknown Petunia hybrida (Petunia) unknow Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism (By similarity). Tissue specificity: Expressed in midvein, lamina and periphery of leaves (at protein level). Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. PTM: Contains three disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 21143680##22700981 Plant J. 2010 Dec;64(6):1002-1017.##J Biol Chem. 2012 Aug 3;287(32):27033-46. "Breuillin F, Schramm J, Hajirezaei M, Ahkami A, Favre P, Druege U, Hause B, Bucher M, Kretzschmar T, Bossolini E, Kuhlemeier C, Martinoia E, Franken P, Scholz U, Reinhardt D.##Poth AG, Mylne JS, Grassl J, Lyons RE, Millar AH, Colgrave ML, Craik DJ." Phosphate systemically inhibits development of arbuscular mycorrhiza in Petunia hybrida and represses genes involved in mycorrhizal functioning.##Cyclotides associate with leaf vasculature and are the products of a novel precursor in petunia (Solanaceae). DRAMP00321 QSISCAESCVWIPCATSLIGCSCVNSRCIYSK 32 Acyclotide phyb-M (Plant defensin) B3EWH7 Belongs to the cyclotide family (Bracelet subfamily) Unknown Petunia hybrida (Petunia) unknow Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism (By similarity). Tissue specificity: Expressed in midvein, lamina and periphery of leaves (at protein level). Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. PTM: Contains three disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 22700981 J Biol Chem. 2012 Aug 3;287(32):27033-46. "Poth AG, Mylne JS, Grassl J, Lyons RE, Millar AH, Colgrave ML, Craik DJ." Cyclotides associate with leaf vasculature and are the products of a novel precursor in petunia (Solanaceae). DRAMP00322 SEPQXGRDAGGAL 13 Insecticidal protein LA-a (Latex abundant protein a; Plant defensin) P86799 Unknown Unknown Morus alba (White mulberry) Insecticidal Unknown Unknown Unknown "Function: Has insecticidal activity when consumed by D. melanogaster larvae. Has low chitinase and chitosanase activity. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan. Ref.1 PTM: Glycosylated; contains galactose." No MICs found on DRAMP database Chitin-binding 20109180 BMC Biochem. 2010 Jan 28;11:6. "Kitajima S, Kamei K, Taketani S, Yamaguchi M, Kawai F, Komatsu A, Inukai Y." Two chitinase-like proteins abundantly accumulated in latex of mulberry show insecticidal activity. DRAMP00323 SEQQXGRDVGGAL 13 Insecticidal protein LA-b (Latex abundant protein b; Plant defensin) P86800 Unknown Unknown Morus alba (White mulberry) Insecticidal Unknown Unknown Unknown "Function: Has insecticidal activity when consumed by D.melanogaster larvae. Has low chitinase and chitosanase activity. Catalytic activity: Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins. Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan. Ref.1 PTM: Glycosylated; contains galactose." No MICs found on DRAMP database Unknown 20109180 BMC Biochem. 2010 Jan 28;11:6. "Kitajima S, Kamei K, Taketani S, Yamaguchi M, Kawai F, Komatsu A, Inukai Y." Two chitinase-like proteins abundantly accumulated in latex of mulberry show insecticidal activity. DRAMP00324 GIFTFEDESTSTVAPAKLYK 20 Protein PR-L1 (Plant defensin) P83363 Belongs to the BetVI family Unknown Lupinus luteus (European yellow lupin) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Pathogenesis-related protein. May have antifungal or antibacterial activity. Induction: By heavy metal ions." No MICs found on DRAMP database Unknown PubMed ID is not availbale J. Plant Physiol. 1999;154:703-708. "Przymusinski R, Gwozdz E.A." Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins. DRAMP00325 SVFAFENEQSSTIAPARLYK 20 Protein PR-L2 (Plant defensin) P83364 Belongs to the BetVI family Unknown Lupinus luteus (European yellow lupin) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Pathogenesis-related protein. May have antifungal or antibacterial activity. Induction: By heavy metal ions." No MICs found on DRAMP database Unknown PubMed ID is not availbale J. Plant Physiol. 1999;154:703-708. "Przymusinski R, Gwozdz E.A." Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins. DRAMP00326 GIFTFEDESTTTVAPAKLYK 20 Protein PR-L3 (Plant defensin) P83365 Belongs to the BetVI family Unknown Lupinus luteus (European yellow lupin) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Pathogenesis-related protein. May have antifungal or antibacterial activity. Induction: By heavy metal ions." No MICs found on DRAMP database Unknown PubMed ID is not availbale J. Plant Physiol. 1999;154:703-708. "Przymusinski R, Gwozdz E.A." Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins. DRAMP00327 SVFAFQDESTSTIAQARLFI 20 Protein PR-L4 (Plant defensin) P83366 Belongs to the BetVI family Unknown Lupinus luteus (European yellow lupin) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Pathogenesis-related protein. May have antifungal or antibacterial activity. Induction: By heavy metal ions." No MICs found on DRAMP database Unknown PubMed ID is not availbale J. Plant Physiol. 1999;154:703-708. "Przymusinski R, Gwozdz E.A." Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins. DRAMP00328 SIFAFQDESPSAIAQAKLFK 20 Protein PR-L5 (Plant defensin) P83367 Belongs to the BetVI family Unknown Lupinus luteus (European yellow lupin) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Pathogenesis-related protein. May have antifungal or antibacterial activity. Induction: By heavy metal ions." No MICs found on DRAMP database Unknown PubMed ID is not availbale J. Plant Physiol. 1999;154:703-708. "Przymusinski R, Gwozdz E.A." Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins. DRAMP00329 GVFTFEDESTSTVAPAKLYK 20 Protein PR-L6 (Plant defensin) P83368 Belongs to the BetVI family Unknown Lupinus luteus (European yellow lupin) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Pathogenesis-related protein. May have antifungal or antibacterial activity. Induction: By heavy metal ions." No MICs found on DRAMP database Unknown PubMed ID is not availbale J. Plant Physiol. 1999;154:703-708. "Przymusinski R, Gwozdz E.A." Heavy metal-induced polypeptides in lupin roots are similar to pathogenesis-related proteins. DRAMP00330 DFVDAHNAARAQVGVGPVHWTVDAYARQYANDRNLVHSATR 41 Pathogenesis-related protein (PR-1; Plant defensin) P83834 Belongs to the CRISP family Unknown Cucumis melo (Muskmelon) unknow Unknown Unknown Unknown Function: Probably involved in the defense reaction of plants against pathogens (By similarity). No MICs found on DRAMP database Unknown 15480331 J Allergy Clin Immunol. 2004 Oct;114(4):896-899. "Asensio T, Crespo JF, Sanchez-Monge R, Lopez-Torrejon G, Somoza ML, Rodriguez J, Salcedo G." Novel plant pathogenesis-related protein family involved in food allergy. DRAMP00331 GVQKSEVVITSA 12 Pathogenesis-related protein (PRP; Plant defensin) C0HJB6 Belongs to the BetVI family Unknown Foeniculum vulgare (Fennel) unknow Unknown Unknown Unknown "Function: Probably involved in the defense reaction of plants against pathogens (By similarity). Allergenic properties: Causes an allergic reaction in human." No MICs found on DRAMP database IgE 23210484 J Agric Food Chem. 2013 Jan 23;61(3):740-746. "Pastorello EA, Farioli L, Stafylaraki C, Scibilia J, Giuffrida MG, Mascheri A, Piantanida M, Baro C, Primavesi L, Nichelatti M, Schroeder JW, Pravettoni V." Fennel allergy is a lipid-transfer protein (LTP)-related food hypersensitivity associated with peach allergy. DRAMP00332 DLDVNVFNR 9 Pathogenesis-related protein (Plant defensin) P85494 Unknown Unknown Ephedra distachya (Joint-fir) (Ephedra vulgaris) Antimicrobial Unknown Unknown Unknown "Function: Probably involved in the defense reaction of plants against pathogens. Domain: Contains 1 barwin domain." No MICs found on DRAMP database Unknown 19157640 J Plant Physiol. 2009 May 15;166(8):831-843. "Uzal EN, G車mez-Ros LV, Hern芍ndez JA, Pedre?o MA, Cuello J, Ros Barcel車 A." Analysis of the soluble cell wall proteome of gymnosperms. DRAMP00333 AVKTITLNLVSPSANRYATFLTEIRDNVRXRSLDYSHSGIDVIGAPSSRDSXLNINFQSP 60 Antiviral protein DAP-32 (Ribosome-inactivating protein; Plant defensin) P24477 Belongs to the ribosome-inactivating protein family (Type 1 RIP subfamily) Unknown Dianthus caryophyllus (Carnation) (Clove pink) Antiviral Unknown Unknown Unknown "Function: Single-chain ribosome-inactivating protein, possessing high antiviral potency and low toxicity to normal cells in culture and to intact animals. Capable of inhibiting HIV-1 infection and replication. Catalytic activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA." "Syncytkia (IC50=0.76 nM), viral coreprotein P24 (IC50=0.71 nM), HIV-RT (IC50=0.76 nM)." Unknown 1936243 FEBS Lett. 1991 Oct 7;291(1):139-144. "Lee-Huang S, Kung HF, Huang PL, Huang PL, Li BQ, Huang P, Huang HI, Chen HC." "A new class of anti-HIV agents: GAP31, DAPs 30 and 32." DRAMP00334 GLDTVSFSTKGATYITYVNFLNELRVKTKPEGNSHGIPSLRKSSDDPGSSFVVAG 55 Antiviral protein GAP-31 (Ribosome-inactivating protein; Plant defensin) P24475 Belongs to the ribosome-inactivating protein family (Type 1 RIP subfamily) Unknown Suregada multiflora (False lime) (Gelonium multiflorum) Antiviral Unknown Unknown Unknown "Function: Single-chain ribosome-inactivating protein, possessing high antiviral potency and low toxicity to normal cells in culture and to intact animals. Capable of inhibiting HIV-1 infection and replication. Catalytic activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA." No MICs found on DRAMP database Unknown 1936243 FEBS Lett. 1991 Oct 7;291(1):139-144. "Lee-Huang S, Kung HF, Huang PL, Huang PL, Li BQ, Huang P, Huang HI, Chen HC." "A new class of anti-HIV agents: GAP31, DAPs 30 and 32." DRAMP00335 NVRFDLSGATSSSYKTFIKN 20 Ribosome-inactivating protein (rRNA N-glycosidase; Plant defensin) P80750 Belongs to the ribosome-inactivating protein family (Type 1 RIP subfamily) Unknown Cucurbita pepo (Vegetable marrow) (Summer squash) unknow Unknown Unknown Unknown Catalytic activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S Rrna. No MICs found on DRAMP database Unknown 9022685 Eur J Biochem. 1996 Dec 15;242(3):585-591. "Yoshinari S, Yokota S, Sawamoto H, Koresawa S, Tamura M, Endo Y." "Purification, characterization and subcellular localization of a type-1 ribosome-inactivating protein from the sarcocarp of Cucurbita pepo." DRAMP00339 GADFQECMKEHSQKQHQHQG 20 Alpha-basrubrin (Fragment; Plants) P83186 Unknown Unknown Basella alba (Malabar spinach) (Basella rubra) "Antifungal, Antiviral" Unknown Unknown Unknown Function: Inhibits HIV-1 reverse transcriptase and cell-free translation. "Fungi: Botrytis cinerea, Mycosphaerella arachidicola, Fusarium oxysporum." Unknown 11688973 Biochem Biophys Res Commun. 2001 Nov 9;288(4):765-770. "Wang H, Ng T.B." Novel antifungal peptides from ceylon spinach seeds. DRAMP00340 KIMAKPSKFYEQLRGR 16 Beta-basrubin (Plants) P83187 Unknown Unknown Basella alba (Malabar spinach) (Basella rubra) "Antifungal, Antiviral" Unknown Unknown Unknown Function: Possesses antifungal activity. Inhibits HIV-1 reverse transcriptase and cell-free translation. "Fungi: Botrytis cinerea, Mycosphaerella arachidicola, Fusarium oxysporum." Unknown 11688973 Biochem Biophys Res Commun. 2001 Nov 9;288(4):765-770. "Wang H, Ng T.B." Novel antifungal peptides from ceylon spinach seeds. DRAMP00341 ANTAFVSSAHNTQKIPAGAPFNRNLRAMLADLRQNAAFAG 40 "Antifungal protein ginkbilobin-1 (Ginkbilobin, GNL; Plants)" P83171 Unknown GNK1 Ginkgo biloba (Ginkgo) (Maidenhair tree) "Antibacterial, Antifungal, Antiviral" Unknown Unknown Unknown Function: Also inhibits HIV-1 reverse transcriptase and proliferation of murine splenocytes. "Gram-positive bacterium: Staphylococcus aureus;##Gram-negative bacteria: Pseudomonas aeruginosa, Escherichia coli.##Fuungi: Botrytis cinerea, Mycosphaerella arachidicola, Fusarium oxysporum, Rhizoctonia solani, Coprinus comatus," Unknown 11118300 Biochem Biophys Res Commun. 2000 Dec 20;279(2):407-411. "Wang H, Ng T.B." "Ginkbilobin, a novel antifungal protein from Ginkgo biloba seeds with sequence similarity to embryo-abundant protein." DRAMP00342 ATITVVNRCSYTVWPGALPGGGVRLDPGQRWALNMPAGTAGAAV 44 Antifungal protein R (Plant defensin) P33044 Unknown Unknown Hordeum vulgare (Barley) Antifungal Unknown Unknown Unknown Function: Has antifungal activity. Inhibits the growth of Trichoderma viridae and Candida albicans. "Fungi: Trichoderma viridae, Candida albicans." Unknown 1936240 FEBS Lett. 1991 Oct 7;291(1):127-131. "Hejgaard J, Jacobsen S, Svendsen I." Two antifungal thaumatin-like proteins from barley grain. DRAMP00343 ATFTVINKCQYTVWAAAVPAGGGQKLDAGQTWSIXXP 37 Antifungal protein S (Plant defensin) P33045 Unknown Unknown Hordeum vulgare (Barley) Antifungal Unknown Unknown Unknown Function: Has antifungal activity. Inhibits the growth of Trichoderma viridae and Candida albicans. "Fungi: Trichoderma viridae, Candida albicans." Unknown 1936240 FEBS Lett. 1991 Oct 7;291(1):127-131. "Hejgaard J, Jacobsen S, Svendsen I." Two antifungal thaumatin-like proteins from barley grain. DRAMP00344 AISYDQVKSSLLPCVGYVRGNNARPAPPNYCKGIRSLKSAARIRLDRQAACKCIKSLAADISDINYGVAAGLPGQCNVHIPYKISPSIDCKRVK 94 Non-specific lipid-transfer protein 6 (LTP; Plants) O24418 Belongs to the plant LTP family LTP6 Gossypium hirsutum (Upland cotton) (Gossypium mexicanum) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). Tissue specificity: Specifically expressed in fiber cells." No MICs found on DRAMP database Lipid-binding 9030188 Biochim Biophys Acta. 1997 Jan 21;1344(2):111-114. "Ma DP, Liu HC, Tan H, Creech RG, Jenkins JN, Chang YF." Cloning and characterization of a cotton lipid transfer protein gene specifically expressed in fiber cells. DRAMP00345 ACEPAQLAVCASAILGGTKPSGECCGNLRAQQGCLCQYVKDPNYGHYVSSPHARDTLNLCGIPVPHC 67 Probable non-specific lipid-transfer protein (LTP; B-FABP; Plants) P20145 Belongs to the plant LTP family LTP2 Hordeum vulgare (Barley) Unknown Unknown Unknown Unknown "Function: Potential phospholipid transfer protein. Tissue specificity: Aleurone. Developmental stage: Maximum mRNA abundance around mid-phase of grain development. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding 7849757 Plant J. 1994 Dec;6(6):849-860. "Kalla R, Shimamoto K, Potter R, Nielsen PS, Linnestad C, Olsen OA." The promoter of the barley aleurone-specific gene encoding a putative 7 kDa lipid transfer protein confers aleurone cell-specific expression in transgenic rice. DRAMP00346 AITCGQVSSALGPCAAYAKGSGTSPSAGCCSGVKRLAGLARSTADKQATCRCLKSVAGAYNAGRAAGIPSRCGVSVPYTISASVDCSKIH 90 Non-specific lipid-transfer protein Cw18 (LTP Cw-18; PKG2316; Plants) Q43871 Belongs to the plant LTP family CW18 Hordeum vulgare (Barley) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Tissue specificity: Highly expressed in leaves and coleoptiles. No expression in roots. Induction: By NaCl, abscisic acid and inoculation with the fungal pathogen E. graminis. PTM: Contains four disulfide bonds 4-52; 14-29; 30-72; 50-86." "Fungi: Fusarim solani (EC50=3-20℅10-6 M), Pseudomonas solanacearum (EC50=3-6℅10-7 M), Pythium aphanidermatum, Clavibacter michiganensis subsp. Sepedonicus (EC50=l-3℅10-7 M)." Lipid-binding 8420795##8281190 FEBS Lett. 1993 Jan 25;316(2):119-122.##Plant J. 1993 Dec;4(6):983-991. "Molina A, Segura A, Garc赤a-Olmedo F.##Molina A, Garc??a-Olmedo F." Lipid transfer proteins (nsLTPs) from barley and maize leaves are potent inhibitors of bacterial and fungal plant pathogens.##Developmental and pathogen-induced expression of three barley genes encoding lipid transfer proteins. DRAMP00347 AISCGQVSSALSPCISYARGNGAKPPVACCSGVKRLAGAAQSTADKQAACRCLKSLATSIKGINMGKVSGVPGKCGVSVPFPISMSTDCNKVH 93 Non-specific lipid-transfer protein 3 (LTP 3; CW-19; CW-20; Plants) Q43766 Belongs to the plant LTP family LTP3 Hordeum vulgare (Barley) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds (By similarity)." "Fungi: Fusarim solani (EC50=3-20℅10-6 M), Pseudomonas solanacearum (EC50=3-6℅10-7 M), Pythium aphanidermatum, Clavibacter michiganensis subsp. Sepedonicus (EC50=l-3℅10-7 M)." Lipid-binding 8420795##8281190 FEBS Lett. 1993 Jan 25;316(2):119-122.##Plant J. 1993 Dec;4(6):983-991. "Molina A, Segura A, Garc赤a-Olmedo F.##Molina A, Garc??a-Olmedo F." Lipid transfer proteins (nsLTPs) from barley and maize leaves are potent inhibitors of bacterial and fungal plant pathogens.##Developmental and pathogen-induced expression of three barley genes encoding lipid transfer proteins. DRAMP00348 AISCGQVSSALSPCISYARGNGAKPPAACCSGVKRLAGAAQSTADKQAACKCIKSAAGGLNAGKAAGIPSMCGVSVPYAISASVDCSKIR 90 Non-specific lipid-transfer protein 4.1 (LTP 4.1; CW-21; Plants) Q43767 Belongs to the plant LTP family LTP4.1 Hordeum vulgare (Barley) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds 4-52; 14-29; 30-72; 50-86." "Fungi: Fusarim solani (EC50=3-20℅10-6 M), Pseudomonas solanacearum (EC50=3-6℅10-7 M), Pythium aphanidermatum, Clavibacter michiganensis subsp. Sepedonicus (EC50=l-3℅10-7 M)." Lipid-binding 8420795##8281190 FEBS Lett. 1993 Jan 25;316(2):119-122.##Plant J. 1993 Dec;4(6):983-991. "Molina A, Segura A, Garc赤a-Olmedo F.##Molina A, Garc??a-Olmedo F." Lipid transfer proteins (nsLTPs) from barley and maize leaves are potent inhibitors of bacterial and fungal plant pathogens.##Developmental and pathogen-induced expression of three barley genes encoding lipid transfer proteins. DRAMP00349 AISCGQVSSALSPCISYARGNGAKPPVACCSGVKRLAGAAQSTADKQAACKCIKSAAGGLNAGKAAGIPSMCGVSVPYAISASVDCSKIR 90 Non-specific lipid-transfer protein 4.2 (LTP 4.2; Low-temperature-responsive protein 4.9; Plants) Q43875 Belongs to the plant LTP family LTP4.2 Hordeum vulgare (Barley) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Induction: By cold. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding 8804389 Mol Gen Genet. 1996 Aug 27;252(1-2):162-168. "Molina A, Diaz I, Vasil IK, Carbonero P, Garc??a-Olmedo F." Two cold-inducible genes encoding lipid transfer protein LTP4 from barley show differential responses to bacterial pathogens. DRAMP00350 AISCGQVSSALSPCISYARGNGAKPPVACCSGVKRLAGAAQSTADKQAACKCIKSAAGGLNAGKAAGIPSMCGVSVPYAISASVDCSKIR 90 Non-specific lipid-transfer protein 4.3 (LTP 4.3; Plants) Q42842 Belongs to the plant LTP family LTP4.3 Hordeum vulgare (Barley) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Induction: By cold. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding 8804389 Mol Gen Genet. 1996 Aug 27;252(1-2):162-168. "Molina A, Diaz I, Vasil IK, Carbonero P, Garc??a-Olmedo F." Two cold-inducible genes encoding lipid transfer protein LTP4 from barley show differential responses to bacterial pathogens. DRAMP00351 AITCGQVTSNLAPCLAYLRNTGPLGRCCGGVKALVNSARTTEDRQIACTCLKSAAGAISGINLGKAAGLPSTCGVNIPYKISPSTDCSKVQ 91 Non-specific lipid-transfer protein 1 (LTP 1; PR-14; Plant defensin) Q42952 Belongs to the plant LTP family LTP1 Nicotiana tabacum (Common tobacco) Unknown Alpha helix (5 helices; 50 residues) "The overall fold of tobacco LTP 1 includes four 汐-helices: H1 (Cys4-Leu18), H2 (Cys27-Val37), H3 (Glu42-Ala55) and H4 (Leu63-Thr72), followed by a C-terminal segment involving three 污-turns." 1T12 resolved by NMR. "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. Binds cis-unsaturated fatty acids and jasmonic acid with a higher affinity than linear chain fatty acids. Formation of the complex with jasmonic acid results in a conformational change facilitating the LPT1 binding on the elicitin plasma membrane receptor that is known to be involved in plant defense induction. May also play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Tissue specificity: High expression in leaf epidermis and shoot apex, and also in root epidermis during seedling germination. PTM: Contains four disulfide bonds." No MICs found on DRAMP database Lipid-binding 8883375##15726627 Plant Physiol. 1996 Oct;112(2):513-524.##Proteins. 2005 May 1;59(2):356-367. "Canevascini S, Caderas D, Mandel T, Fleming AJ, Dupuis I, Kuhlemeier C.##Da Silva P, Landon C, Industri B, Marais A, Marion D, Ponchet M, Vovelle F." Tissue-specific expression and promoter analysis of the tobacco Itp1 gene.##Solution structure of a tobacco lipid transfer protein exhibiting new biophysical and biological features. DRAMP00352 VDCGQVNSSLASCIPFLTGGVASPSASCCAGVQNLKTLAPTSADRRAACECIKAAAARFPTIKQDAASSLPKKCGVDINIPISKTTNCQAIN 92 Non-specific lipid-transfer protein A (NS-LTP A; PLTP; Plants) P10973 Belongs to the plant LTP family Unknown Ricinus communis (Castor bean) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains three disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding PubMed ID is not available Biochim. Biophys. Acta 1986;870:248-255. "Takishima K, Watanabe S, Yamada M, Mamiya G." The amino-acid sequence of the nonspecific lipid transfer protein from germinated castor bean endosperms. DRAMP00353 VNCGQVNKALSSCVPFLTGFDTTPSLTCCAGVMELKRLAPTVKDKRIACECVKTAAARYPNIREDAASSLPYKCGVVINVPISKTTNCHEIN 92 Non-specific lipid-transfer protein B (NS-LTP B; PLTP; Plants) P10974 Belongs to the plant LTP family Unknown Ricinus communis (Castor bean) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding 3191918 Eur J Biochem. 1988 Nov 1;177(2):241-249. "Takishima K, Watanabe S, Yamada M, Suga T, Mamiya G." Amino acid sequences of two nonspecific lipid-transfer proteins from germinated castor bean. DRAMP00354 AVPCSTVDMKAAACVGFATGKDSKPSQACCTGLQQLAQTVKTVDDKKAICRCLKASSKSLGIKDQFLSKIPAACNIKVGFPVSTNTNCETIH 92 "Non-specific lipid-transfer protein C, cotyledon-specific isoform (NS-LTP C; PLTP; Plants)" "P10975, Q43120" Belongs to the plant LTP family Unknown Ricinus communis (Castor bean) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding 1783615 J Biochem. 1991 Nov;110(5):823-831. "Tsuboi S, Suga T, Takishima K, Mamiya G, Matsui K, Ozeki Y, Yamada M." "Organ-specific occurrence and expression of the isoforms of nonspecific lipid transfer protein in castor bean seedlings, and molecular cloning of a full-length cDNA for a cotyledon-specific isoform." DRAMP00355 AVPCSTVDMKAAACVGFATGKDSKPSSACCTGLQQLAQTVKSVDDKKAICRCLKASSKSLGIKDQFLSKIPAACNIKVGFPVSTATNCETIH 92 "Non-specific lipid-transfer protein D, cotyledon-specific isoform (NS-LTP D; Plants)" Q43119 Belongs to the plant LTP family Unknown Ricinus communis (Castor bean) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding PubMed ID is not available Planta 1992;187:367-371. "Weig A, Komor E." The lipid-transfer protein C of Ricinus communis L.: isolation of two cDNA sequences which are strongly and exclusively expressed in cotyledons after germination. DRAMP00356 GITCGMVSSKLAPCIGYLKGGPLGGGCCGGIKALNAAAATTPDRKTACNCLKSAANAIKGINYGKAAGLPGMCGVHIPYAISPSTNCNAVH 91 Non-specific lipid-transfer protein (LTP; PLTP; Plants) P10976 Belongs to the plant LTP family Unknown Spinacia oleracea (Spinach) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding 16667945##3609015 Plant Physiol. 1991 Jan;95(1):164-170.##Eur J Biochem. 1987 Jul 15;166(2):387-391. "Bernhard WR, Thoma S, Botella J, Somerville CR.##Bouillon P, Drischel C, Vergnolle C, Duranton H, Kader JC." Isolation of a cDNA Clone for Spinach Lipid Transfer Protein and Evidence that the Protein Is Synthesized by the Secretory Pathway.##The primary structure of spinach-leaf phospholipid-transfer protein. DRAMP00357 TTSEAAISCGQVSSAIALCLSYARGQGFAPSAGCCSGVRSLNSAARTTADRRAACNCLKNAARGISGLNAGNAASIPSKCGVSVPYTISTSTDCSRVS 98 Non-specific lipid-transfer protein 1 (LTP 1; Plants) "Q43193, Q43195" Belongs to the plant LTP family LTP1 Sorghum bicolor (Sorghum) (Sorghum vulgare) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding 7958959 Gene. 1994 Oct 21;148(2):305-308. "Pel?“se-Siebenbourg F, Caelles C, Kader JC, Delseny M, Puigdom?“nech P." A pair of genes coding for lipid-transfer proteins in Sorghum vulgare. DRAMP00358 ATTSEAAVTCGQVSSAIGPCLSYARGQGSGPSAGCCSGVRSLNSAARTTADRRAACNCLKNAARGIRGLNVGKAASIPSKCGVSIPYTISTSTDCSRVS 99 Non-specific lipid-transfer protein 2 (LTP 2; Plants) Q43194 Belongs to the plant LTP family LTP2 Sorghum bicolor (Sorghum) (Sorghum vulgare) Unknown Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding 7958959 Gene. 1994 Oct 21;148(2):305-308. "Pel?“se-Siebenbourg F, Caelles C, Kader JC, Delseny M, Puigdom?“nech P." A pair of genes coding for lipid-transfer proteins in Sorghum vulgare. DRAMP00359 AISCGQVASAIAPCISYARGQGSGPSAGCCSGVRSLNNAARTTADRRAACNCLKNAAAGVSGLNAGNAASIPSKCGVSIPYTISTSTDCSRVN 93 Non-specific lipid-transfer protein (LTP; PLTP; Plants) P19656 Belongs to the plant LTP family Unknown Zea mays (Maize) Unknown Alpha helix (6 helices; 53 residues) The global fold involving four helical fragments connected by three loops and a C-terminal tail without regular secondary structures is stabilized by four disulfide bridges. The most striking feature of this structure is the existence of an internal hydrophobic cavity running through the whole molecule. (Ref.3) "1AFH resolved by NMR.##1FK0, 1FK1, 1FK2, 1FK3 resolved by X-ray." "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Allergenic properties: Causes an allergic reaction in human. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Lipid-binding 2022320##7735835##8845747 Gene. 1991 Mar 1;99(1):133-136.##Structure. 1995 Feb 15;3(2):189-199.##Protein Sci. 1996 Apr;5(4):565-577. "Arondel V, Tchang F, Baillet B, Vignols F, Grellet F, Delseny M, Kader JC, Puigdom?“nech P.##Shin DH, Lee JY, Hwang KY, Kim KK, Suh SW.##Gomar J, Petit MC, Sodano P, Sy D, Marion D, Kader JC, Vovelle F, Ptak M." Multiple mRNA coding for phospholipid-transfer protein from Zea mays arise from alternative splicing.##High-resolution crystal structure of the non-specific lipid-transfer protein from maize seedlings.##Solution structure and lipid binding of a nonspecific lipid transfer protein extracted from maize seeds. DRAMP00360 ISCQDVKQSLAPCLPYVTGRAPKPA 25 Non-specific lipid-transfer protein 1 (LTP 1; Plants) P86527 Belongs to the plant LTP family Unknown Nigella sativa (Black cumin) Antifungal Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Fungi: Fusarium oxysporum and Phytophthora infestans. Lipid-binding 19621049 Bioorg Khim. 2009 May-Jun;35(3):344-349. "Oshchepkova IuI, Veshkurova ON, Rogozhin EA, Musoliamov AKh, Smirnov AN, Odintsova TI, Egorov TsA, Grishin EV, Salikhov ShI." Isolation of the lipid-transporting protein Ns-LTP1 from seeds of the garden fennel flower (Nigella sativa). DRAMP00361 ITCPQVTQSLAPCVPYLISG 20 Non-specific lipid-transfer protein (LTP; Harmalin; Plants) B3EWH4 Belongs to the plant LTP family Unknown Peganum harmala (Syrian rue) (Harmal peganum) "Antifungal, Antiviral, Anticancer" Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Inhibits cell proliferation of cervical carcinoma cell line HeLa (IC50=2.74 ?M), gastric carcinoma cell line MGC-7 (IC50=3.13 ?M), esophageal carcinoma cell line Eca-109 (IC50=0.7 ?M) and melanoma B16 cells (IC50=1.47 ?M). Has antifungal activity. Induces caspase-dependent apoptosis in cell line Eca-109. Demonstrates inhibitory effect on HIV-1 reverse transcriptase (IC50=1.26 ?M). Biophysicochemical properties: pH dependence (Stable between pH 4 and 10); Temperature dependence (Thermostable. Retains antifungal activity between 4 degrees Celsius and 60 degrees Celsius. Activity reduced after 30 min at 80 degrees Celsius)." "Fungi: Penicillium digitatum (IC50=37.5 ?M), Alternaria alternata (IC50=1.5 ?M), Rhizopus stolonifer (IC50=8.44 ?M) and Magnaporthe grisea (IC50=12.19 ?M)." Lipid-binding PubMed ID is not available Submitted (MAR-2012) to UniProtKB "Ma XJ, Liu DL, Tang HS, Wang Y, Sun SR." "Purification and characterization of a novel protein from Peganum harmala seeds with antifungal, antiproliferation and anti-HIV-1 reverse transcriptase activities." DRAMP00362 AISCGTVSGALVPCLTYLKGGPGPSPQCCGGVKRLNGAARTTIDRRAACNCLKSSAGSISGLKPGNVATLPGKCGVRLPYTISTSTNCNTIRF 93 Non-specific lipid-transfer protein 1 (Lc-LTP1; Plants) A0AT28 Belongs to the plant LTP family Unknown Lens culinaris (Lentil) (Cicer lens) Antibacterial Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds 4-51; 14-28; 29-74; 49-88." No MICs found on DRAMP database Lipid-binding 17511608 Biochemistry (Mosc). 2007 Apr;72(4):430-438. "Finkina EI, Balandin SV, Serebryakova MV, Potapenko NA, Tagaev AA, Ovchinnikova TV." Purification and primary structure of novel lipid transfer proteins from germinated lentil (Lens culinaris) seeds. DRAMP00363 AISCGAVTSDLSPCLTYLTGGPGPSPQCCGGVKKLLAAANTTPDRQAACNCLKSAAGSITKLNTNNAAALPGKCGVNIPYKISTTTNCNTVKF 93 Non-specific lipid-transfer protein 2 (Lc-LTP2; Plants) "A0AT29, P84255" Belongs to the plant LTP family Unknown Lens culinaris (Lentil) (Cicer lens) Antibacterial Alpha helix (6 helices; 57 residues) Unknown 2LJO resolved by NMR. "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds 4-51; 14-28; 29-74; 49-88." No MICs found on DRAMP database Lipid-binding 17511608##17511608##PubMed ID is not available Biochemistry (Mosc). 2007 Apr;72(4):430-438.##Biochemistry (Mosc). 2007 Apr;72(4):430-438.##To be Published. "Finkina EI, Balandin SV, Serebryakova MV, Potapenko NA, Tagaev AA, Ovchinnikova TV.##Finkina EI, Balandin SV, Serebryakova MV, Potapenko NA, Tagaev AA, Ovchinnikova TV.##Shenkarev, Z, Mineev, K, Gizatullina, A, Finkina, E, Arseniev, A, Ovchinnikova, T." Purification and primary structure of novel lipid transfer proteins from germinated lentil (Lens culinaris) seeds.##Purification and primary structure of novel lipid transfer proteins from germinated lentil (Lens culinaris) seeds.##Solution structure of lipid transport protein Lc-LTP2 from germinated lentil (Lens Culinaris) seeds. DRAMP00364 AISCGAVTSDLSPCLTYLTGGPGPSPQCCGGVKKLLAAANTTPDRQAACNCLKSAAGSITKLNTNNAAALPGKCGVNIPYKISTSTNCNTVKF 93 Non-specific lipid-transfer protein 4 (Lc-LTP4; Plants) "A0AT33, P84255" Belongs to the plant LTP family Unknown Lens culinaris (Lentil) (Cicer lens) Antibacterial Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds 4-51; 14-28; 29-74; 49-88." No MICs found on DRAMP database Lipid-binding 17511608 Biochemistry (Mosc). 2007 Apr;72(4):430-438. "Finkina EI, Balandin SV, Serebryakova MV, Potapenko NA, Tagaev AA, Ovchinnikova TV." Purification and primary structure of novel lipid transfer proteins from germinated lentil (Lens culinaris) seeds. DRAMP00365 AISCGAVTGDLSPCLTYLTGGPGPSPQCCGGVKKLLAAANTTPDRQAACNCMKSAASSITKLNTNNAAALPGKCGVNIPYKISTSTNCNTVK 92 Non-specific lipid-transfer protein 5 (Lc-LTP5; Plants) A0AT31 Belongs to the plant LTP family Unknown Lens culinaris (Lentil) (Cicer lens) Antibacterial Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds 4-51; 14-28; 29-74; 49-88." No MICs found on DRAMP database Lipid-binding 17511608 Biochemistry (Mosc). 2007 Apr;72(4):430-438. "Finkina EI, Balandin SV, Serebryakova MV, Potapenko NA, Tagaev AA, Ovchinnikova TV." Purification and primary structure of novel lipid transfer proteins from germinated lentil (Lens culinaris) seeds. DRAMP00366 AISCGAVTSDLSPCLTYLTGGPGPSPQCCGGVKKLLAAANTTPDRQAACNCLKSAAGSITKLNTNNAAALPGKCGVDIPYKISTSTNCNTVKF 93 Non-specific lipid-transfer protein 6 (Lc-LTP6; Plants) A0AT32 Belongs to the plant LTP family Unknown Lens culinaris (Lentil) (Cicer lens) Antibacterial Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds 4-51; 14-28; 29-74; 49-88." No MICs found on DRAMP database Lipid-binding 17511608 Biochemistry (Mosc). 2007 Apr;72(4):430-438. "Finkina EI, Balandin SV, Serebryakova MV, Potapenko NA, Tagaev AA, Ovchinnikova TV." Purification and primary structure of novel lipid transfer proteins from germinated lentil (Lens culinaris) seeds. DRAMP00367 AISCGAVTSDLSPCLTYLTGGPGPSPQCCGGVKKLLAAANTTPDRQAACNCLKSAAGSITKLNTNNAAALPGKCGVNIPYKISTTTNCNTVK 92 Non-specific lipid-transfer protein 7 (Lc-LTP7; Plants) "A0AT29, P84255" Belongs to the plant LTP family Unknown Lens culinaris (Lentil) (Cicer lens) Antibacterial Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds 4-51; 14-28; 29-74; 49-88." No MICs found on DRAMP database Lipid-binding 17511608 Biochemistry (Mosc). 2007 Apr;72(4):430-438. "Finkina EI, Balandin SV, Serebryakova MV, Potapenko NA, Tagaev AA, Ovchinnikova TV." Purification and primary structure of novel lipid transfer proteins from germinated lentil (Lens culinaris) seeds. DRAMP00368 AISCGAVTSDLSPCLTYLTGGPGPSPQCCGGVKKLLAAANTTPDRQAACNCLKSAAGSITKLNTNNAAALPGKCGVNIPYKISTSTNCNTVK 92 Non-specific lipid-transfer protein 8 (Lc-LTP8; Plants) "A0AT33, P84255" Belongs to the plant LTP family Unknown Lens culinaris (Lentil) (Cicer lens) Antibacterial Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds 4-51; 14-28; 29-74; 49-88." No MICs found on DRAMP database Lipid-binding 17511608 Biochemistry (Mosc). 2007 Apr;72(4):430-438. "Finkina EI, Balandin SV, Serebryakova MV, Potapenko NA, Tagaev AA, Ovchinnikova TV." Purification and primary structure of novel lipid transfer proteins from germinated lentil (Lens culinaris) seeds. DRAMP00369 ITCGLVASKLAPCIGYLQGAPGPSAACCGGIKSLNSAAASPADRKTACTCLKSAATSIKGINYGKAASLPRQCGVSVPYAISPNTNCNAIH 91 IWF1 (Bv-LTP1; Plant defensin) Q43748 Belongs to the plant LTP family IWF1' Beta vulgaris (Sugar beet) Antifungal Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Also has fungicide activity. Fungi: Cercospora beticola. Lipid-binding 8790287 Plant Mol Biol. 1996 Jun;31(3):539-552. "Nielsen KK, Nielsen JE, Madrid SM, Mikkelsen JD." New antifungal proteins from sugar beet (Beta vulgaris L.) showing homology to non-specific lipid transfer proteins. DRAMP00370 ITCGQVTSQVAGCLSYLQRGGAPAPXXXXGIRNLXXMA 38 Antifungal protein 5 (CW-5; Plants) P83139 Belongs to the plant LTP family Unknown Malva parviflora (Little mallow) (Cheeseweed mallow) Antifungal Unknown Unknown Unknown "Function: Possesses potent antifungal activity against F. graminearum but not P. infestans. Miscellaneous: Under low salt conditions, possesses potent antifungal activity but activity is drastically reduced under high salt conditions." Fungi: Fusarium graminearum. Unknown 11302747 Biochem Biophys Res Commun. 2001 Apr 20;282(5):1224-1228. "Wang X, Bunkers GJ, Walters MR, Thoma RS." Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora). DRAMP00371 GPLGGCCGGIKKSAAAGISGINYGIAAGLPGKCGVNIPYKISPSTDCSKVQ 51 Non-specific lipid-transfer protein (LTP; Plant defensin) B3A0N2 Belongs to the plant LTP family Unknown Lycium barbarum (Matrimony vine) unknow Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). Miscellaneous: Causes an allergic reaction." No MICs found on DRAMP database Lipid-binding PubMed ID is not availbale Submitted (SEP-2011) to UniProtKB "Carnes J, Lopez-matas M.A, Saez R." Allergic sensitization to Goji berries is mediated by a 7 kDa band (LTP). DRAMP00372 AVSCGDVTSSIAPCLSYVMGRESSPSSSCCSGVRTLNGKASSSADRRTACSCLKNMASSFRNLNMGNAASIPSKCGVSVAFPISTSVDCSKIN 93 Non-specific lipid-transfer protein 3 (Os-LTP3) "Q2QYL3, Q42976, Q8GZV1" Belongs to the plant LTP family LTP110-A Oryza sativa Japonica Group Antifungal Unknown Unknown Unknown "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. May possess an antifungal activity and protect the plant against pathogens. PTM: Problely contains four disulfide bonds 4-52; 14-29; 30-75; 50-89. " "Pyricularia oryzae, Xanthomonas oryzae." Unknown 14659081 J Biochem Mol Biol. 2003 Nov 30;36(6):603-607. "Ge X, Chen J, Li N, Lin Y, Sun C, Cao K." Resistance Function: of rice lipid transfer protein LTP110. DRAMP00373 ALSCGTVNSNLAACIGYLTQNAPLARGCCTGVTNLNNMAXTTP 43 Seed non-specific lipid transfer protein-like (ns-LTP; Plants) P29420 Belongs to the plant LTP family Unknown Raphanus sativus (Radish) Antifungal Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. This isoform inhibits the hyphal growth of several fungi in vitro. "Fungi: Alternaria brassicola (MUCL 20297) (IC50=48 ?g/mL), Ascochyta pisi (MUCL 20164) (IC50=41 ?g/mL), Botrytis cinerea (MUCL 30158) (IC50=45 ?g/mL), Colletotrichum lindemuthianum (MUCL 9577) (IC50=25 ?g/mL), Fusarium culmorum (IMI 180420) (IC50=20 ?g/mL), Fusarium oxysporum f. sp. lycopersici (MUCL 909) (IC50=54 ?g/mL), Fusarium oxysporum f. sp. pisi (IMI 236441) (IC50=58 ?g/mL), Nectria haematococca (Collection Van Etten 26022) (IC50=100 ?g/mL), Phoma betae (MUCL 9916) (IC50=18 ?g/mL), Pyricularia oryzae (MUCL 30166) (IC50=10 ?g/mL), Trichoderma hamatum (MUCL 29736) (IC50=30 ?g/mL), Verticillium dahliae (MUCL 6963) (IC50=7 ?g/mL)." Lipid-binding 16653017 Plant Physiol. 1992 Oct;100(2):1055-1058. "Terras FR, Goderis IJ, Van Leuven F, Vanderleyden J, Cammue BP, Broekaert WF." In vitro antifungal activity of a radish (Raphanus sativus L.) seed protein homologous to non-specific lipid transfer proteins. DRAMP00374 AVSCNTVIADLYPCLSYVTQGGPVPTLCCNGLTTLKSQAQTSVDRQGVCRCIKSAIGGLTLSPRTIQNALELPSKCGVDLPYKFSPSTDCDSIQ 94 Non-specific lipid-transfer protein 6 (LTP 6; Plants) Q9LDB4 Belongs to the plant LTP family LTP6 Arabidopsis thaliana (Mouse-ear cress) Unknown Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). Their biological Function: is presently No comments found on DRAMP databasen. No MICs found on DRAMP database Lipid-binding 10940464 Plant Sci. 2000 Aug 8;157(1):1-12. "Arondel12 V V, Vergnolle2 C, Cantrel C, Kader J." Lipid transfer proteins are encoded by a small multigene family in Arabidopsis thaliana. DRAMP00375 PAGPFRIPPRXRXEFQ 16 Antifungal protein 1 small subunit (CW-1; Plants) P83140 Unknown Unknown Malva parviflora (Little mallow) (Cheeseweed mallow) Antifungal Unknown Unknown Unknown "Function: Possesses very potent antifungal activity against F. graminearum. Subunit structure: Heterodimer of a large and a small subunit. Miscellaneous: Antimicrobial activity is not affected by salt concentration." Fungi:##At low salt condition: Fusarium graminearum (IC50=2.5 ppm).##At high salt condition: Fusarium graminearum (IC50=10 ppm). Unknown 11118343 Biochem Biophys Res Commun. 2000 Dec 20;279(2):669-673. "Wang X, Bunkers GJ." Potent heterologous antifungal proteins from cheeseweed (Malva parviflora). DRAMP00376 VAGPFRIPPLRREFQ 15 Antifungal protein 1 large subunit (CW-1; Plants) P83141 Unknown Unknown Malva parviflora (Little mallow) (Cheeseweed mallow) Antifungal Unknown Unknown Unknown "Function: Possesses antifungal activity against P. infestans but not F. graminearum. Subunit structure: Heterodimer of a large and a small subunit. Miscellaneous: Antimicrobial activity is not affected by salt concentration." Fungi: Phytophthora infestans. Unknown 11118343 Biochem Biophys Res Commun. 2000 Dec 20;279(2):669-673. "Wang X, Bunkers GJ." Potent heterologous antifungal proteins from cheeseweed (Malva parviflora). DRAMP00377 SDYSRKRDPPQKYEEE 16 Antifungal protein 2 small subunit (CW-2; Plants) P83142 Unknown Unknown Malva parviflora (Little mallow) (Cheeseweed mallow) Antifungal Unknown Unknown Unknown "Function: Possesses antifungal activity against P. infestans but not F. graminearum. Subunit structure: Heterodimer of a large and a small subunit. Miscellaneous: Antimicrobial activity is not affected by salt concentration." Fungi: Phytophthora infestans. Unknown 11118343 Biochem Biophys Res Commun. 2000 Dec 20;279(2):669-673. "Wang X, Bunkers GJ." Potent heterologous antifungal proteins from cheeseweed (Malva parviflora). DRAMP00378 PEDPQRRYQEXQREXRXQQE 20 Antifungal protein 2 large subunit (CW-2; Plants) P83143 Unknown Unknown Malva parviflora (Little mallow) (Cheeseweed mallow) Antifungal Unknown Unknown Unknown "Function: Possesses antifungal activity against P. infestans but not F. graminearum. Subunit structure: Heterodimer of a large and a small subunit. Miscellaneous: Antimicrobial activity is not affected by salt concentration." Fungi: Phytophthora infestans. Unknown 11118343 Biochem Biophys Res Commun. 2000 Dec 20;279(2):669-673. "Wang X, Bunkers GJ." Potent heterologous antifungal proteins from cheeseweed (Malva parviflora). DRAMP00379 PEDPQRRYQEEQRRE 15 Antifungal protein 3 (CW-3; Plants) P83137 Unknown Unknown Malva parviflora (Little mallow) (Cheeseweed mallow) Antibacterial; Antifungal Unknown Unknown Unknown "Function: Possesses antifungal activity. Miscellaneous: Antimicrobial activity is not affected by salt concentration." Fungi: Phytophthora infestans. Unknown 11302747 Biochem Biophys Res Commun. 2001 Apr 20;282(5):1224-1228. "Wang X, Bunkers GJ, Walters MR, Thoma RS." Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora). DRAMP00380 DRQIDMEEQQLEKLNKQDRXPGLRYAAKQQMXTXRMG 37 Antifungal protein 4 (CW-4; Plants) P83138 Unknown Unknown Malva parviflora (Little mallow) (Cheeseweed mallow) Antibacterial; Antifungal Unknown Unknown Unknown "Function: Possesses antifungal activity. Miscellaneous: Antimicrobial activity is not affected by salt concentration. Biophysicochemical properties: Temperature dependence (Thermostable). Still active after heating at 100 degrees Celsius for 20 minutes." Fungi: Phytophthora infestans. Unknown 11302747 Biochem Biophys Res Commun. 2001 Apr 20;282(5):1224-1228. "Wang X, Bunkers GJ, Walters MR, Thoma RS." Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora). DRAMP00381 SGECNMYGRCPPGYCCSKFGYCGGVRAYCG 30 IWF4 (Plants) No entry found Unknown Unknown Beta vulgaris (Sugar beet) Antifungal Unknown Unknown Unknown "Tissue specificity: IWF4 mRNA is expressed in the aerial parts of the plant only, with a constitutive expression in young and mature leaves and in young flowers." Fungi: Cercospora beticola (IC50<2 ?g/mL). Chitin-binding 9008390 Plant Physiol. 1997 Jan;113(1):83-91. "Nielsen KK, Nielsen JE, Madrid SM, Mikkelsen JD." Characterization of a new antifungal chitin-binding peptide from sugar beet leaves. DRAMP00382 TFPKCAPTRPPGPKPCDINNFKSKFWHIWRA 31 Datucin (Glycopeptide; Plants) No entry found Unknown Unknown Datura stramonium Antifungal Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 23193597 Biopolymers 2012; 98(4):332-337. Mandal SM. A Novel Hydroxyproline Rich Glycopeptide from Pericarp of Datura stramonium: Proficiently Eradicate the Biofilm of Antifungals Resistant Candida albicans. DRAMP00383 AKCIKNGKGCREDQGPPFCCSGFCYRQVGWARGYCKNR 38 Antimicrobial peptide 1 (Mc-AMP1; knottin-type peptide; Plant defensin) O81338 Belongs to the AMP family Unknown Mesembryanthemum crystallinum (Common ice plant) (Cryophytum crystallinum) "Antibacterial, Antifungal" Bridge Unknown Unknown "Function: Possesses antifungal and antibacterial activity. Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. PTM: Contains three disulfide bonds 3-20; 10-24; 18-35." "Gram-positive bacteria: Bacillus megaterium (IC50=2 ?g/mL), Sarcina lutea (IC50=50 ?g/mL).##Fungi: Alternaria brassicola (IC50=6 ?g/mL), Ascochyta pisi (IC50=6 ?g/mL), Botrytis cinerea (IC50=2 ?g/mL), Cercospora beticola (IC50=2 ?g/mL), Colletotrichum lindemuthianum (IC50=1 ?g/mL), Fusarium culmorum (IC50=3 ?g/mL), Fusarium oxysporum f. sp. Pisi (IC50=5 ?g/mL), Fusarium oxysporum f. sp. Lycopersici (IC50=10 ?g/mL), Nectria haematococca (IC50=0.5 ?g/mL), Phoma betae (IC50=6 ?g/mL), Pyrenophora tritici-repentis (IC50=20 ?g/mL), Pyricularia oryzae (IC50=0.5 ?g/mL), Rhizoctonia solani (IC50=15 ?g/mL), Verticiliium dahliae (IC50=0.5 ?g/mL), Venturia inaequalis (IC50=1 ?g/mL)." Unknown PubMed ID is not available Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases. "Michalowski C.B, Bohnert H.J." Antimicrobial peptide 1 from the common ice plant. DRAMP00386 AISCGQVSSAIGPCLSYARGQGSAPSAGCC 30 EcLTP (E. crus-galli lipid transfer protein; Plants) No entry found Unknown Unknown Echinochloa crusgalli L. (seeds of weed cereal barnyard grass) Antifungal Unknown Unknown Unknown Function: Possesses antifungal activity. Fungi: Phytophthora infestans (IC50=6 ?M). Unknown 22940285 Peptides. 2012 Nov;38(1):33-40. "Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK." Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds. DRAMP00387 GSGRGSCRSQCMRRHEDEPWRVQECVSQCRRRRGGGD 37 Antimicrobial peptide 1 (EcAMP1; hairpin-like peptides; Plants) P86698 Unknown Unknown Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli) Antifungal Alpha helix (3 helices; 20 residues) The peptide adopts a disulfide-stabilized ?㊣-helical hairpin structure in aqueous solution and thus represents a novel fold among naturally occurring antimicrobial peptides. 2L2R resolved by NMR. "Function: EcAMP1 can inhibit growth of several fungal phytopathogens. Does not destroy spores but rather inhibits hyphal growth during germination. Does not affect spore germination in A. niger, C. graminicola, D. maydis and T. album. Does not inhibit trypsin. Confocal microscopy revealed intensive EcAMP1 binding to the surface of fungal conidia followed by internalization and accumulation in the cytoplasm without disturbance of membrane integrity. Tissue specificity: Seed." "Fungi: Alternaria alternata (EC50=16.0㊣2.3 ?M), A. solani (EC50=14.0㊣2.1 ?M), Aspergillus niger (EC50>32 ?M), Bipolaris sorokiniana (EC50=18.2㊣2.7 ?M), Colletotrichum graminicola (EC50>10 ?M), Diplodia maydis (EC50>10 ?M), Fusarium graminearum (EC50=4.5㊣1.4 ?M), Fusarium oxysporum (EC50=8.5㊣1.6 ?M), F. solani (EC50=4.0㊣1.2 ?M), F. verticillioides (EC50=8.1㊣2.3 ?M), Phoma betae (EC50=6.0㊣1.5 ?M), Phytophthora infestans (EC50=16.3㊣2.5 ?M), Pythium debaryanum (EC50=12.0㊣1.7 ?M), P. ultimum (EC50=14.4㊣2.1 ?M), Tritirachium album (EC50>32 ?M)." Unknown 22940285##21561864 Peptides. 2012 Nov;38(1):33-40.##J Biol Chem. 2011 Jul 15;286(28):25145-25153. "Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK.##Nolde SB, Vassilevski AA, Rogozhin EA, Barinov NA, Balashova TA, Samsonova OV, Baranov YV, Feofanov AV, Egorov TA, Arseniev AS, Grishin EV." Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds.##Disulfide-stabilized helical hairpin structure and activity of a novel antifungal peptide EcAMP1 from seeds of barnyard grass (Echinochloa crus-galli). DRAMP00388 DRCSQQCQHHRDPDRKQQCMRECRRHQGRSD 31 Antimicrobial peptide 2 (EcAMP2; Plants) B3EWR4 Unknown Unknown Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli) Antifungal Unknown Unknown Unknown "Function: EcAMP2 inhibits spore germination of P. infestans with an IC50 of 24 ?M but have no antibacterial activity. PTM: Contains two disulfide bonds (By similarity)." Fungi: Phytophthora infestans (IC50=24 ?M). Unknown 22940285 Peptides. 2012 Nov;38(1):33-40. "Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK." Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds. DRAMP00389 DRCSQQCQHHRDPDRKQQCMRECRRH 26 EcAMP2.1 (truncated EcAMP2 without five C-terminal residues) B3EWR4 Unknown Unknown Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli) Antifungal Unknown Unknown Unknown "Function: EcAMP2.1 inhibits spore germination of P. infestans with an IC50 of 24 ?M but have no antibacterial activity. PTM: Contains two disulfide bonds (By similarity)." Fungi: Phytophthora infestans (IC50=24 ?M). Unknown 22940285 Peptides. 2012 Nov;38(1):33-40. "Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK." Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds. DRAMP00390 ANKCIIDCMKVKTTCGDECKGAGFKTGGCALPPDIMKCCHNC 42 Antimicrobial peptide 3 (ToAMP3; Cys-rich; Plant defensin) B3EWQ3 Unknown Unknown Taraxacum officinale (Common dandelion) (Leontodon taraxacum) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Possesses antifungal activity. Also active against bacterial species P. syringae, B. subtilis and X. campestris. Tissue specificity: Expressed in flowers but not in leaves, seeds or roots (at protein level)." Fungi: Aspergillus niger (IC50=1.2 ?M). Unknown 22640720 Peptides. 2012 Aug;36(2):266-271. "Astafieva AA, Rogozhin EA, Odintsova TI, Khadeeva NV, Grishin EV, Egorov TsA." Discovery of novel antimicrobial peptides with unusual cysteine motifs in dandelion Taraxacum officinale Wigg. flowers. DRAMP00391 GGKCTVDWGGQGGGRRLPSPLFCCYKPTRICYLNQETCETETCP 44 Antimicrobial peptide 2 (ToAMP2; Cys-rich; Plant defensin) B3EWQ2 Unknown Unknown Taraxacum officinale (Common dandelion) (Leontodon taraxacum) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Possesses antifungal activity. Also active against bacterial species P. syringae, B. subtilis and X. campestris. Tissue specificity: Expressed in flowers but not in leaves, seeds or roots (at protein level)." "Fungi: Botrytis cinerea (IC50=5.2 ?M), Aspergillus niger (IC50=2.6 ?M), Bipolaris sorokiniana (IC50=5.2 ?M), Pythium debaryanum (IC50=2.6 ?M)." Unknown 22640720 Peptides. 2012 Aug;36(2):266-271. "Astafieva AA, Rogozhin EA, Odintsova TI, Khadeeva NV, Grishin EV, Egorov TsA." Discovery of novel antimicrobial peptides with unusual cysteine motifs in dandelion Taraxacum officinale Wigg. flowers. DRAMP00392 VAKCTEESGGKYFVFCCYKPTRICYMNEQKCESTCIGK 38 Antimicrobial peptide 1 (ToAMP1; Cys-rich; Plant defensin) B3EWQ1 Unknown Unknown Taraxacum officinale (Common dandelion) (Leontodon taraxacum) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Possesses antifungal activity. Also active against bacterial species P. syringae, B. subtilis and X. campestris. Tissue specificity: Expressed in flowers but not in leaves, seeds or roots (at protein level)." "Fungi: Botrytis cinerea (IC50=5.8 ?M), Aspergillus niger (IC50=5.6 ?M)." Unknown 22640720 Peptides. 2012 Aug;36(2):266-271. "Astafieva AA, Rogozhin EA, Odintsova TI, Khadeeva NV, Grishin EV, Egorov TsA." Discovery of novel antimicrobial peptides with unusual cysteine motifs in dandelion Taraxacum officinale Wigg. flowers. DRAMP00393 IQCGESCVWIPCISSAWGCSCKNKICSS 28 Hedyotide B2 (hB2; Uncyclotides; Plants) No entry found Unknown Unknown Hedyotis biflora (aerial tissues) Antifungal Unknown Unknown Unknown Function: Possesses antifungal activity. "Gram-negative bacterium: Escherichia coli (MIC>80 ?M);##Gram-positive bacteria: Streptococcus salivarius(MIC>80 ?M), Staphylococcus epidermidis (MIC>80 ?M), Streptococcus aureus (MIC>80 ?M)." Unknown 21979955 J Biol Chem. 2011 Dec 30;286(52):44833-44844. "Nguyen GK, Zhang S, Wang W, Wong CT, Nguyen NT, Tam JP." Discovery of a linear cyclotide from the bracelet subfamily and its disulfide mapping by top-down mass spectrometry. DRAMP00394 FSGSVNQACSGFGWK 15 Antimicrobial peptide1 (Plant defensin) P85484 Unknown Unknown Pinus halepensis (Aleppo pine) Antimicrobial Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 19157640 J Plant Physiol. 2009 May 15;166(8):831-143. "Uzal EN, G??mez-Ros LV, Hern??ndez JA, Pedre?㊣o MA, Cuello J, Ros Barcel?? A." Analysis of the soluble cell wall proteome of gymnosperms. DRAMP00395 GIPCGESCVWIPCITSAIGCSCKSKVCYRN 30 Cyclotide vitri-A (Vbc6; Plant defensin) B1NRR3 Unknown Unknown Viola biflora (Yellow wood violet) Antimicrobial Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Problely contains three disulfide bonds 4-20; 8-22; 13-27. This is a cyclic peptide." No MICs found on DRAMP database Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00396 NLCERASLTWTGNCGNTGHCDTQCRNWESAKHGACHKRGNWKCFCYFDC 49 "Ct-AMP1 (CtAMP1, C. ternatea-antimicrobial peptide 1; Plant defensin)" No entry found Unknown Unknown Clitoria ternatea "Antibacterial, Antifungal" Unknown Unknown Unknown No comments found on DRAMP database "Gram-positive bacterium: Bacillus subtilis (IC50=15 ?g/mL).##Medium A: Botrytis cinerea (IC50=20 ?g/ml), Cladosporium sphaerospermum (IC50=6 ?g/ml), Fusarium culmorum (IC50=10 ?g/ml), Leptosphaeria maculans (IC50=6 ?g/ml), Penicillium digitatum (IC50=20 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=2 ?g/ml), Verticilium albo-atrum (IC50=2 ?g/ml). NOTE: Medium B = 1/2 strength potato dextrose broth.##Medium B: Botrytis cinerea (IC50>100 ?g/ml), Cladosporium sphaerospermum (IC50=100 ?g/ml), Fusarium culmorum (IC50=50 ?g/ml), Leptosphaeria maculans (IC50=20 ?g/ml), Penicillium digitatum (IC50=80 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=80 ?g/ml), Verticilium albo-atrum (IC50>100 ?g/ml).##NOTE: Medium B = Medium A supplemented with 1 mM CaCl2 and 50 mM KCI." Unknown 7628617 FEBS Lett. 1995 Jul 17;368(2):257-262. "Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF." "Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae." DRAMP00397 KFCEKPSGTWSGVCGNSGACKDQCIRLEGAKHGSCNYKPPAHRCICYYEC 50 Defensin D1 (Ns-D1; Plant defensin) P86972 Belongs to the DEFL family Unknown Nigella sativa (Black cumin) Antifungal Bridge Unknown Unknown "Function: Antimicrobial peptide active against fungi, Gram-positive and Gram-negative bacteria. Has no effect on spore germination. Destroys spores in germinated conidia by disruption of cell walls and membranes in A. niger and B. sorokiniana. Causes vacuolization of germinated macro- and microconidia in F. oxysporum, F. graminearum and F. culmorum. Strongly inhibits growth of P. infestans on potato tubers above concentrations of 13.6 ?g/ml. PTM: Contains four disulfide bonds." "Fungi: Aspergillus niger (IC50=3.5 ?g/ml), Bipolaris sorokiniana (IC50=3.0 ?g/ml), Fusarium oxysporum (IC50=9.5 ?g/ml), Fusarium graminearum (IC50=6.9 ?g/ml), Fusarium culmorum (IC50=6.9 ?g/ml) and Botrytis cinerea (IC50=27.4 ?g/ml).##Gram-positive bacteria: Clavibacter michiganensis (1.4 cm) and Bacillus subtilis (1.3 cm);##Gram-negative bacteria: Pseudomonas syringae (0.9 cm), Erwinia carotovora (0.7 cm) and Escherichia coli (1.2 cm).##NOTE: Inhibition zone; Defensin concentration (11 ?g in 50 ??l)." Unknown 21144761 Plant Physiol Biochem. 2011 Feb;49(2):131-137. "Rogozhin EA, Oshchepkova YI, Odintsova TI, Khadeeva NV, Veshkurova ON, Egorov TA, Grishin EV, Salikhov SI." Novel antifungal defensins from Nigella sativa L. seeds. DRAMP00398 KFCEKPSGTWSGVCGNSGACKDQCIRLEGAKHGSCNYKLPAHRCICYYEC 50 Defensin D2 (Ns-D2; Plant defensin) P86973 Belongs to the DEFL family Unknown Nigella sativa (Black cumin) Antifungal Bridge Unknown Unknown "Function: Antimicrobial peptide active against fungi, Gram-positive and Gram-negative bacteria. Has no effect on spore germination. Destroys spores in germinated conidia by disruption of cell walls and membranes in Aspergillus niger and B.sorokiniana. Causes vacuolization of germinated macro- and microconidia in Fusarium oxysporum, F.graminearum and F.culmorum. Strongly inhibits growth of P.infestans on potato tubers above concentrations of 3.4 ?g/ml. PTM: Contains four disulfide bonds." "Fungi: Aspergillus niger (IC50=3.5 ?g/ml), Bipolaris sorokiniana (IC50=1.8 ?g/ml), Fusarium oxysporum (IC50=5.3 ?g/ml), Fusarium graminearum (IC50=6.9 ?g/ml), Fusarium culmorum (IC50=6.9 ?g/ml) and Botrytis cinerea (IC50=13.7 ?g/ml).##Gram-positive bacteria: Clavibacter michiganensis (1.5 cm) and Bacillus subtilis (1.3 cm);##Gram-negative bacteria: Pseudomonas syringae (1.3 cm), Erwinia carotovora (0.7 cm) and Escherichia coli (1.4 cm).##NOTE: Inhibition zone; Defensin concentration (11 ?g in 50 ??l)." Unknown 21144761 Plant Physiol Biochem. 2011 Feb;49(2):131-137. "Rogozhin EA, Oshchepkova YI, Odintsova TI, Khadeeva NV, Veshkurova ON, Egorov TA, Grishin EV, Salikhov SI." Novel antifungal defensins from Nigella sativa L. seeds. DRAMP00399 NTCEHLADTYRGVCFTNASCDDHCKNKAHLISGTCHDWKCFCTQNC 46 Defensin-like protein 39 (Disease resistance response protein 39; Plant defensin) Q01784 Belongs to the DEFL family PI39 Pisum sativum (Garden pea) Antifungal Unknown Unknown Unknown "Function: Possesses antifungal activity (By similarity). Tissue specificity: Pods. Induction: Upon contact with the plant pathogen fungus Fusarium solani. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 1799696 Mol Plant Microbe Interact. 1991 Jul-Aug;4(4):324-331. "Chiang CC, Hadwiger LA." The Fusarium solani-induced expression of a pea gene family encoding high cysteine content proteins. DRAMP00400 NLCERASLTWTGNCGNTGHCDTQCRNWESAKHGACHKRGNWKCFCYFNC 49 "Defensin-like protein 1 (Defensin AMP1, CtAMP1; Plant defensin)" Q7M1F2 Belongs to the DEFL family Unknown Clitoria ternatea (Butterfly pea) Antifungal Bridge Unknown Unknown "Function: Possesses antimicrobial activity sensitive to inorganic cations. Binds specifically to the fungal plasma membrane. Has no inhibitory effect on insect gut alpha-amylase. PTM: Contains four disulfide bonds (By similarity)." "Fungi: Botrytis cinerea (IC50=20 ?g/ml), Cladosporium sphaerospermum (IC50=6 ?g/ml), Fusarium culmorum (IC50=10 ?g/ml), Leptosphaeria maculans (IC50=6 ?g/ml), Penicillium digitatum (IC50=20 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=2 ?g/ml), Verticilium albo-atrum (IC50=2 ?g/ml), Neurospora crassa (IC50<0.3 ?g/ml)." fungal plasma membrane 7628617##10656585 FEBS Lett. 1995 Jul 17;368(2):257-262.##Mol Plant Microbe Interact. 2000 Jan;13(1):54-61. "Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF.##Thevissen K, Osborn RW, Acland DP, Broekaert WF." "Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae.##Specific binding sites for an antifungal plant defensin from Dahlia (Dahlia merckii) on fungal cells are required for antifungal activity." DRAMP00401 DSECLKEYGGDVGFPFCAPRIFPTICYTRCRENKGAKGGRCIWGEGTNVKCLCDYCNDSPFDQ 63 Defensin-like protein 2 (MTI-2; Trypsin inhibitor 2; Plant defensin) P26780 Belongs to the DEFL family Unknown Sinapis alba (White mustard) (Brassica hirta) Antifungal Bridge Unknown Unknown "Function: Inhibits bovine beta-trypsin and alpha-chymotrypsin on a 1:1 molar basis. PTM: Problely contains four disulfide bonds 4-56; 17-41; 26-51; 30-53." No MICs found on DRAMP database Unknown 7750566##1451776 FEBS Lett. 1995 May 8;364(2):179-181.##FEBS Lett. 1992 Apr 13;301(1):10-14. "Ceci LR, Spoto N, de Virgilio M, Gallerani R.##Menegatti E, Tedeschi G, Ronchi S, Bortolotti F, Ascenzi P, Thomas RM, Bolognesi M, Palmieri S." "The gene coding for the mustard trypsin inhibitor-2 is discontinuous and wound-inducible.##Purification, inhibitory properties and amino acid sequence of a new serine proteinase inhibitor from white mustard (Sinapis alba L.) seed." DRAMP00402 XTCESPSHKFKGPCATNRNCES 22 Defensin D1 (So-D1; Antimicrobial peptide D1; Plant defensin) P81572 Belongs to the DEFL family Unknown Spinacia oleracea (Spinach) Antibacterial Unknown Unknown Unknown Function: Antimicrobial peptide. Active against Gram-positive and Gram-negative bacterial pathogens. Gram-positive bacterium: Clavibacter michiganensis;##Gram-negative bacterium: Ralstonia solanacearum. Unknown 9762899 FEBS Lett. 1998; 435: 159-162. "Segura A, Moreno M, Molina A, Garc??a-Olmedo F." Novel defensin subfamily from spinach (Spinacia oleracea). DRAMP00403 GIFSSRKCKTPSKTFKGICTRDSNCDTSCRYEGYPAGDCKGIRRRCMCSKPC 52 Defensin D2 (So-D2; Antimicrobial peptide D2; Plant defensin) P81571 Belongs to the DEFL family Unknown Spinacia oleracea (Spinach) "Antibacterial, Antifungal" Bridge Unknown Unknown "Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens. Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots. Developmental stage: Present throughout the life of the leaf. PTM: Contains four disulfide bonds (By similarity)." Gram-positive bacterium: Clavibacter michiganensis;##Gram-negative bacterium: Ralstonia solanacearum.##Fungi: Fusarium culmorum. Unknown 9762899 FEBS Lett. 1998; 435: 159-162. "Segura A, Moreno M, Molina A, Garc??a-Olmedo F." Novel defensin subfamily from spinach (Spinacia oleracea). DRAMP00404 GIFSSRKCKTVSKTFRGICTRNANC 25 Defensin D3 (So-D3; Antimicrobial peptide D3; Plant defensin) P81570 Belongs to the DEFL family Unknown Spinacia oleracea (Spinach) "Antibacterial, Antifungal" Bridge Unknown Unknown "Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens. Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots. Developmental stage: Present throughout the life of the leaf." Fungi: Fusarium spp. Unknown 9762899 FEBS Lett. 1998; 435: 159-162. "Segura A, Moreno M, Molina A, Garcia-Olmedo F." Novel defensin subfamily from spinach (Spinacia oleracea). DRAMP00405 MFFSSKKCKTVSKTFRGPCVRNA 23 Defensin D4 (So-D4; Antimicrobial peptide D4; Plant defensin) P81569 Belongs to the DEFL family Unknown Spinacia oleracea (Spinach) "Antibacterial, Antifungal" Bridge Unknown Unknown "Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens. Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots. Developmental stage: Present throughout the life of the leaf." Fungi: Fusarium spp. Unknown 9762899 FEBS Lett. 1998; 435: 159-162. "Segura A, Moreno M, Molina A, Garcia-Olmedo F." Novel defensin subfamily from spinach (Spinacia oleracea). DRAMP00406 MFFSSKKCKTVXKTFRGPCVRNAN 24 Defensin D5 (So-D5; Antimicrobial peptide D5; Plant defensin) P81568 Belongs to the DEFL family Unknown Spinacia oleracea (Spinach) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens. Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots. Developmental stage: Present throughout the life of the leaf." "Gram-positive bacterium: Clavibacter michiganensis;##Gram-negative bacterium: Ralstonia solanacearum.##Fungi: Fusarium culmorum, Fusarium solani, Bipolaris maydis and Colletotrichum lagenarium." Unknown 9762899 FEBS Lett. 1998; 435: 159-162. "Segura A, Moreno M, Molina A, Garcia-Olmedo F." Novel defensin subfamily from spinach (Spinacia oleracea). DRAMP00407 GIFSNMYXRTPAGYFRGPXGYXXN 24 Defensin D6 (So-D6; Antimicrobial peptide D6; Plant defensin) P81567 Belongs to the DEFL family Unknown Spinacia oleracea (Spinach) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens. Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots. Developmental stage: Present throughout the life of the leaf." Gram-positive bacterium: Clavibacter michiganensis (EC50=1 ?M);##Gram-negative bacterium: Ralstonia solanacearum (EC50=6 ?M).##Fungi: Fusarium solani (EC50=11 ?M). Unknown 9762899 FEBS Lett. 1998; 435: 159-162. "Segura A, Moreno M, Molina A, Garcia-Olmedo F." Novel defensin subfamily from spinach (Spinacia oleracea). DRAMP00408 GIFSSRKCKTPSKTFKGYCTRDSNCDTSCRYEGYPAGD 38 Defensin D7 (So-D7; Antimicrobial peptide D7; Plant defensin) P81573 Belongs to the DEFL family Unknown Spinacia oleracea (Spinach) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens. Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots. Developmental stage: Present throughout the life of the leaf." Fusarium spp. Unknown 9762899 FEBS Lett. 1998; 435: 159-162. "Segura A, Moreno M, Molina A, Garcia-Olmedo F." Novel defensin subfamily from spinach (Spinacia oleracea). DRAMP00409 KTCENLADTY 10 Defensin-like protein (Sesquin; Plant defensin) P84868 Belongs to the DEFL family Unknown Vigna unguiculata subsp. sesquipedalis (Yard-Long bean) "Antibacterial, Antifungal, Antiviral" Unknown Unknown Unknown Function: Has antifungal and antibacterial activity. Has mitogenic activity towards murine splenocytes. Inhibits the proliferation of M1 leukemia and MCF-7 breast cancer cells in vitro. Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase. "Fungi: Botrytis cinerea (IC50=2.5㊣0.01 ?M), Fusarium oxysporum (IC50=1.4㊣0.02 ?M), Mycosphaerella arachidicola (IC50=0.15㊣0.002 ?M).##Gram-positive bacteria: Bacillus megaterium, Mycobacterium phlei;##Gram-negative bacteria: Escherichia coli, Proteus vulgaris." Unknown 15949629 Peptides. 2005 Jul;26(7):1120-1126. "Wong JH, Ng TB" "Sesquin, a potent defensin-like antimicrobial peptide from ground beans with inhibitory activities toward tumor cells and HIV-1 reverse transcriptase." DRAMP00410 QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHK 44 Defensin-like protein 1 (Bn-AFP1; Plant defensin) "P69240, P30225, Q41163" Belongs to the DEFL family AFP1 Brassica napus (Rape) Antifungal Rich Unknown Unknown "Function: Possesses antifungal activity sensitive to inorganic cations. Subunit structure: Forms oligomers in its native state. PTM: Problely contains one disulfide bond." "Fungi: Alternaria brassicola (IC50=3 ?g/ml), Botrytis cinerea (IC50=1.50 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Fusarium oxysporum f.sp.lycopersici (IC50=1.80 ?g/ml), Pyricularia oryzae (IC50=0.25 ?g/ml), Verticiliium dahliae (IC50=0.80 ?g/ml)." Unknown 8422949 FEBS Lett. 1993 Feb 1;316(3):233-240. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF." A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species. DRAMP00411 QKLCERPSGTWSGVCGNNNACKN 23 Defensin-like protein 2 (Bn-AFP2; Plant defensin) P30226 Belongs to the DEFL family Unknown Brassica napus (Rape) Antifungal Rich Unknown Unknown "Function: Possesses antifungal activity sensitive to inorganic cations. Subunit structure: Forms oligomers in its native state." "Fungi: Alternaria brassicola (IC50=75 ?g/ml), Botrytis cinerea(IC50> 100 ?g/ml), Fusarium culmorum (IC50=38 ?g/ml), Fusarium oxysporum f.sp.lycopersici (IC50=42 ?g/ml), Pyricularia oryzae (IC50=3 ?g/ml), Verticiliium dahliae (IC50=15 ?g/ml)." Unknown 8422949 FEBS Lett. 1993 Feb 1;316(3):233-240. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF." A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species. DRAMP00412 QKLCERPSGTWSGVCGNNNACKNQCIN 27 Defensin-like protein 1 (Br-AFP1; Plant defensin) P30227 Belongs to the DEFL family Unknown Brassica rapa (Turnip) Antifungal Unknown Unknown Unknown "Function: Possesses antifungal activity sensitive to inorganic cations. Subunit structure: Forms oligomers in its native state." "Fungi: Alternaria brassicola (IC50=3 ?g/ml), Botrytis cinerea(IC50=1.5 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Fusarium oxysporum f.sp. lycopersici (IC50=1.8 ?g/ml), Pyricularia oryzae (IC50=0.25 ?g/ml), Verticiliium dahliae (IC50=0.8 ?g/ml)." Unknown 8422949 FEBS Lett. 1993 Feb 1;316(3):233-240. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF." A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species. DRAMP00413 QKLCERPSGTXSGVCGNNNACKNQCIR 27 Defensin-like protein 2 (Br-AFP2; Plant defensin) P30228 Belongs to the DEFL family Unknown Brassica rapa (Turnip) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Probably acts by disturbing membrane functions with its amphipathic structure (By similarity). "Fungi: Alternaria brassicola (IC50=75 ?g/ml), Botrytis cinerea(IC50>100 ?g/ml), Fusarium culmorum (IC50=38 ?g/ml), Fusarium oxysporum f.sp. lycopersici (IC50=42 ?g/ml), Pyricularia oryzae (IC50=3 ?g/ml), Verticiliium dahliae (IC50=15 ?g/ml)." Unknown 8422949 FEBS Lett. 1993 Feb 1;316(3):233-240. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF." A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species. DRAMP00414 QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC 51 Raphanus sativus Antifungal Protein 1 (Rs-AFP1; Plant defensin) "P69241, P30225, Q41163" Belongs to the DEFL family AFP1 Raphanus sativus (Radish) Antifungal Combine helix and strand structure "The molecule adopts a compact globular fold comprising an alpha-helix from Asn18 till Leu28 and a triple-stranded beta-sheet (beta 1 = Lys2-Arg6, beta 2 = His33-Tyr38 and beta 3 = His43-Pro50). The central strand of this beta-sheet is connected by two disulfide bridges (Cys21-Cys45 and Cys25-Cys47) to the alpha-helix. The connection between beta-strand 2 and 3 is formed by a type VIa beta-turn." 1AYJ resolved by NMR. "Function: Possesses antifungal activity sensitive to inorganic cations. Subunit structure: Forms oligomers in its native state. PTM: Contains four disulfide bonds 4-51; 15-36; 21-45; 25-47." "Fungi: Alternaria brassicola (IC50=15 ?g/ml), Ascochyta pisi (IC50=5 ?g/ml), Botrytis cinerea (IC50=8 ?g/ml), Cercospora beticola (IC50=2 ?g/ml), Colletotrichum lindemuthianum (IC50=100 ?g/ml), Fusarium culmorum (IC50=5 ?g/ml), Fusarium oxysporum f.sp.lycopersici (IC50=30 ?g/ml), Fusarium oxysporum f.sp.pisi (IC50=15 ?g/ml), Mycosphaerella fijiensis var.fijiensis (IC50=4 ?g/ml), Nectria haematococca (IC50=6 ?g/ml), Phoma betae (IC50=2 ?g/ml), Phytophthora infestans (IC50=3 ?g/ml), Pyrenophora tritici-repentis (IC50=3 ?g/ml), Pyricularia oryzae (IC50=0.3 ?g/ml, Rhizoctonia solani (IC50=100 ?g/ml), Sclerotinia sclerotiorum (IC50=20 ?g/ml), Septoria nodorum (IC50=20 ?g/ml), Trichoderma hamatum (IC50=6 ?g/ml), Verticillium dahliae (IC50=5 ?g/ml). [NOTE: Synthetic low ionic strength growth medium]" Unknown 1639777##9636715 FEBS Lett. 1993; 316: 233-240.##J Mol Biol. 1998 May 29;279(1):257-270. "Terras FR, Schoofs HM, De Bolle MF, Van Leuven F, Rees SB, Vanderleyden J, Cammue BP, Broekaert WF.##Fant F, Vranken W, Broekaert W, Borremans F." A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Determination of the three-dimensional solution structure of Raphanus sativus antifungal protein 1 by 1H NMR. DRAMP00415 QKLCQRPSGTWSGVCGNNNACKNQCIRLEKARHGSCNYVFPAHKCICYFPC 51 Raphanus sativus Antifungal Protein 2 (Rs-AFP2; Plant defensin) "P30230, Q003I2" Belongs to the DEFL family AFP2 Raphanus sativus (Radish) Antifungal Bridge Unknown Unknown "PTM: Contains four disulfide bonds 4-51;15-36;21-45;25-47, and Pyrrolidone carboxylic acid at position 1." "Fungi: Alternaria brassicola (IC50=2 ?g/ml), Ascochyta pisi (IC50=4 ?g/ml), Botrytis cinerea (IC50=2 ?g/ml), Cercospora beticola (IC50=2 ?g/ml), Colletotrichum lindemuthianum (IC50=3 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Fusarium oxysporum f.sp.lycopersici (IC50=2 ?g/ml), Fusarium oxysporum f.sp.pisi (IC50=2 ?g/ml), Mycosphaerella fijiensis var.fijiensis (IC50=1.5 ?g/ml), Nectria haematococca (IC50=2 ?g/ml), Phoma betae (IC50=1 ?g/ml), Phytophthora infestans (IC50=25 ?g/ml), Pyrenophora tritici-repentis (IC50=1.5 ?g/ml), Pyricularia oryzae (IC50=0.4 ?g/ml), Rhizoctonia solani (IC50>100 ?g/ml), Sclerotinia sclerotiorum (IC50>100 ?g/ml), Septoria nodorum (IC50=15 ?g/ml), Trichoderma hamatum (IC50=2 ?g/ml), Verticillium dahliae (IC50=1.5 ?g/ml), Venturia inaequalis (IC50=25 ?g/ml). [NOTE: Synthetic low ionic strength growth medium]" Unknown 7780308 Plant Cell. 1995 May;7(5):573-588. "Terras FR, Eggermont K, Kovaleva V, Raikhel NV, Osborn RW, Kester A, Rees SB, Torrekens S, Van Leuven F, Vanderleyden J, et al." Small cysteine-rich antifungal proteins from radish: their role in host defense. DRAMP00418 QKLCERPSGTWSGVCGNNGACRNQCIRLERARHGSCNYVFPAHKCICYFPC 51 Hc-AFP4 (Plant defensin) No entry found Unknown Hc-AFP4 Heliophila coronopifolia (South African Brassicaceae species) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity. PTM: Contains four disulfide bonds." "Fungi: Botrytis cinerea (IC50=15-20 ?g/ml), Fusarium solani (IC50=5-10 ?g/ml)." Unknown 22032337 BMC Res Notes. 2011 Oct 28;4:459. "de Beer A, Vivier MA." Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes. DRAMP00419 RYCERSSGTWSGVCGNTDKCSSQCQRLEGAAHGSCNYVFPAHKCICYYPC 50 Hc-AFP3 (Plant defensin) No entry found Unknown Hc-AFP3 Heliophila coronopifolia (South African Brassicaceae species) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity. PTM: Contains four disulfide bonds." "Fungi: Botrytis cinerea (IC50=20-25 ?g/ml), Fusarium solani (IC50>25 ?g/ml)." Unknown 22032337 BMC Res Notes. 2011 Oct 28;4:459. "de Beer A, Vivier MA." Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes. DRAMP00420 QKLCERPSGTWSGVCGNNNACRNQCINLEKARHGSCNYVFPAHKCICYFPC 51 Hc-AFP2 (Plant defensin) No entry found Unknown Hc-AFP2 Heliophila coronopifolia (South African Brassicaceae species) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity. PTM: Contains four disulfide bonds." "Fungi: Botrytis cinerea (IC50=10-15 ?g/ml), Fusarium solani (IC50=10-15 ?g/ml)." Unknown 22032337 BMC Res Notes. 2011 Oct 28;4:459. "de Beer A, Vivier MA." Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes. DRAMP00421 RYCERSSGTWSGVCGNSGKCSNQCQRLEGAAHGSCNYVFPAHKCICYYPC 50 Hc-AFP1 (Plant defensin) No entry found Unknown Hc-AFP1 Heliophila coronopifolia (South African Brassicaceae species) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity. PTM: Contains four disulfide bonds." "Fungi: Botrytis cinerea (IC50>25 ?g/ml), Fusarium solani (IC50>25 ?g/ml)." Unknown 22032337 BMC Res Notes. 2011 Oct 28;4:459. "de Beer A, Vivier MA." Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes. DRAMP00424 KLCERSSGTWSGVCGNNNACKNQCINLEGARHGSCNYVFPYHRCICYFPC 50 Br-AFP1 (Defensin 1.2; Plant defensin) No entry found Unknown Unknown Brassica rapa subsp. Chinensis Antifungal Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 8422949##7628617 FEBS Lett. 1993 Feb 1;316(3):233-240.##FEBS Lett. 1995 Jul 17;368(2):257-262. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF." "A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae." DRAMP00426 DGVKLCDVPSGTWSGHCGSSSKCSQQCKDREHFAYGGACHYQFPSVKCFCKRQC 54 Defensin-like protein 1 (Hs-AFP1; Plant defensin) "Q7M1F4, P0C8Y5" Belongs to the DEFL family Unknown Heuchera sanguinea (Coralbells) Antifungal Bridge Unknown Unknown "Function: Possesses antifungal activity insensitive to inorganic cations. Causes germ tubes and hyphae to swell and form multiple hyphal buds. Binds to the plasma membrane of the fungus. Has no inhibitory effect on insect gut alpha-amylase. PTM: Contains four disulfide bonds (By similarity)." "Fungi: Botrytis cinerea (IC50=6 ?g/ml), Cladosporium sphaerospermum (IC50=1 ?g/ml), Fusarium culmorum (IC50=1 ?g/ml), Leptosphaeria maculans (IC50=25 ?g/ml), Penicillium digitatum (IC50=1?g/ml), Trichoderma viride (IC50=15 ?g/ml), Septoria tritiei (IC50=0.5 ?g/ml), Verticillium albo-atrum (IC50=0.5 ?g/ml), Neurospora crassa (IC50=12 ?g/ml). " "chitin, mannan, galactocerebrosides, and sphingomyelin (Mycopathologia. 1998-1999;144:87-91)" 7628617##9405418##16284838 FEBS Lett. 1995 Jul 17;368(2):257-262.##J Biol Chem. 1997 Dec 19;272(51):32176-32181.##Mycopathologia. 1998-1999;144(2):87-91. "Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF.##Thevissen K, Osborn RW, Acland DP, Broekaert WF.##De Lucca AJ, Jacks TJ, Broekaert WJ." "Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae.##Specific, high affinity binding sites for an antifungal plant defensin on Neurospora crassa hyphae and microsomal membranes.##Fungicidal and binding properties of three plant peptides." DRAMP00427 AICKKPSKFFKGACGRDADCEKACDQENWPGGVCVPFLRCECQRSC 46 Defensin-like protein AX1 (Antifungal protein AX1; Plant defensin) P81493 Belongs to the DEFL family Unknown Beta vulgaris (Sugar beet) "Antibacterial, Antifungal, Antiviral" Unknown Unknown Unknown "Function: Strong inhibiting activity against C. beticola and other filamentous fungi. Little or no effect against bacteria. Tissue specificity: Leaves and flowers. PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity)." "Fungi: Cercospora beticola, Botrytis cinerea, Fusarium graminearum, Bipolaris maydis." Unknown 7655063 Mol Plant Microbe Interact. 1995 May-Jun;8(3):424-434. "Kragh KM, Nielsen JE, Nielsen KK, Dreboldt S, Mikkelsen JD." Characterization and localization of new antifungal cysteine-rich proteins from Beta vulgaris. DRAMP00428 ATCRKPSMYFSGACFSDTNCQKACNREDWPNGKCLVGFKCECQRPC 46 Defensin-like protein AX2 (Antifungal protein AX2; Cys-rich; Plant defensin) "P82010, P81510" Belongs to the DEFL family Unknown Beta vulgaris (Sugar beet) "Antibacterial, Antifungal, Antiviral" Unknown Unknown Unknown "Function: Strong inhibiting activity against C. beticola and other filamentous fungi. Little or no effect against bacteria. Tissue specificity: Leaves and flowers. PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity)." "Fungi: Cercospora beticola, Botrytis cinerea, Fusarium graminearum, Bipolaris maydis." Unknown 7655063 Mol Plant Microbe Interact. 1995 May-Jun;8(3):424-434. "Kragh KM, Nielsen JE, Nielsen KK, Dreboldt S, Mikkelsen JD." Characterization and localization of new antifungal cysteine-rich proteins from Beta vulgaris. DRAMP00429 LCNERPSQTWSGNCGNTAHCDKQCQDWEKASHGACHKRENHWKCFCYFNC 50 Aesculus hippocastanum antimicrobial protein 1 (Ah-AMP1; Cys-rich; Plant defensin) Q7M1F3 Belongs to the DEFL family Unknown Aesculus hippocastanum (Horse chestnut) "Antibacterial, Antifungal" Combine helix and strand structure Unknown 1BK8 resolved by NMR. "Function: Possesses antimicrobial activity sensitive to inorganic cations. Binds specifically to the fungal plasma membrane. Has no inhibitory effect on insect gut alpha-amylase. PTM: Contains four disulfide bonds 2-50; 14-35; 20-44; 24-46 (By similarity)." "Gram-positive bacterium: Bacillus subtilis (IC50=100 ?g/mL).##Fungi: [MA: Botrytis cinerea (IC50=25 ?g/mL), Cladosporium sphaerospermum (IC50=0.5 ?g/mL), Fusarium culmorum (IC50=12 ?g/mL), Leptosphaeria maculans (IC50=0.5 ?g/mL), Penicillium digitatum (IC50=6 ?g/mL), Trichoderma viride (IC50>100 ?g/mL), Septoria tritiei (IC50=0.5 ?g/mL), Verticilium albo-atrum (IC50=6 ?g/mL). MA+: Botrytis cinerea (IC50>100 ?g/mL), Cladosporium sphaerospermum (IC50=12 ?g/mL), Fusarium culmorum (IC50>100 ?g/mL), Leptosphaeria maculans (IC50=6 ?g/mL), Penicillium digitatum (IC50=25 ?g/mL), Trichoderma viride (IC50>100 ?g/mL), Septoria tritiei (IC50=1.5 ?g/mL), Verticilium albo-atrum (IC50>100 ?g/mL)].##NOTE: MA+ = MA supplemented with 1 mM CaCl2 and 50 mM KCl." Binds specifically to the fungal plasma membrane. 7628617##10591099##10656585 FEBS Lett. 1995 Jul 17;368(2):257-262.##Proteins. 1999 Nov 15;37(3):388-403.##Mol Plant Microbe Interact. 2000 Jan;13(1):54-61. "Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF.##Fant F, Vranken WF, Borremans FA.##Thevissen K, Osborn RW, Acland DP, Broekaert WF." "Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae.##The three-dimensional solution structure of Aesculus hippocastanum antimicrobial protein 1 determined by 1H nuclear magnetic resonance.##Specific binding sites for an antifungal plant defensin from Dahlia (Dahlia merckii) on fungal cells are required for antifungal activity." DRAMP00430 RVCESQSHGFKGACTGDHNCALVCRNEGFSGGNCRGFRRRCFCTLKC 47 Defensin-like protein 1 (Cp-thionin I; Cp-thionin-1; Gamma-thionin I; Plant defensin) P83399 Belongs to the DEFL family Unknown Vigna unguiculata (Cowpea) Unkonw Bridge Unknown Unknown "Function: Inhibits trypsin but not chymotrypsin. Subunit structure: Monomer and homodimer. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)." No MICs found on DRAMP database Unknown 12112698 Proteins. 2002 Aug 1;48(2):311-319. "Melo FR, Rigden DJ, Franco OL, Mello LV, Ary MB, Grossi de S?? MF, Bloch C Jr." "Inhibition of trypsin by cowpea thionin: characterization, molecular modeling, and docking." DRAMP00432 RVCRRRSAGFKGVCMSDHNCAQVCLQEGYGGGNCDGIMRQCKCIRQC 47 Defensin-like protein 1 (Gamma-zeathionin-1; Plant defensin) P81008 Belongs to the DEFL family Unknown Zea mays (Maize) Antifungal Bridge Unknown Unknown "Function: Sodium channel blocker. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)." No MICs found on DRAMP database Unknown PubMed ID is not available Protein Pept. Lett. 1996;3:267-274. "Castro M.S, Fontes W, Morhy L, Bloch C. Jr." Complete amino acid sequences of two gamma-thionins from maize (Zea mays L.) seeds. DRAMP00433 RVCMGKSQHHSFPCISDRLCSNECVKEDGGWTAGYCHLRYCRCQKAC 47 Defensin-like protein 2 (Gamma-zeathionin-2; Plant defensin) P81009 Belongs to the DEFL family Unknown Zea mays (Maize) Antifungal Bridge Unknown Unknown "Function: Sodium channel blocker. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)." No MICs found on DRAMP database Unknown PubMed ID is not available Protein Pept. Lett. 1996;3:267-274. "Castro M.S, Fontes W, Morhy L, Bloch C. Jr." Complete amino acid sequences of two gamma-thionins from maize (Zea mays L.) seeds. DRAMP00434 KICRRRSAGFKGPCMSNKNCAQVCQQEGWGGGNCDGPFRRCKCIRQC 47 Defensin-like protein 1 (Gamma-1-purothionin; Plant defensin) P20158 Belongs to the DEFL family Unknown Triticum aestivum (Wheat) Antifungal Bridge "Gamma 1-P has a well-defined triple-stranded antiparallel beta-sheet (residues 1-6, 31-34, and 39-47), an alpha-helix (residues 16-28), and the corresponding connecting loops. Three disulfide bridges are located in the hydrophobic core holding together the alpha-helix and the beta-sheet and forming a cysteine-stabilized alpha-helical (CSH) motif." Unknown PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43. No MICs found on DRAMP database Unknown 2226781##8380707 FEBS Lett. 1990 Sep 17;270(1-2):191-194.##Biochemistry. 1993 Jan 19;32(2):715-724. "Colilla FJ, Rocher A, Mendez E.##Bruix M, Jim??nez MA, Santoro J, Gonz??lez C, Colilla FJ, M??ndez E, Rico M. " Gamma-Purothionins: amino acid sequence of two polypeptides of a new family of thionins from wheat endosperm.##Solution structure of gamma 1-H and gamma 1-P thionins from barley and wheat endosperm determined by 1H-NMR: a structural motif common to toxic arthropod proteins. DRAMP00435 KVCRQRSAGFKGPCVSDKNCAQVCLQEGWGGGNCDGPFRRCKCIRQC 47 Defensin-like protein 2 (Gamma-2-purothionin; Plant defensin) P20159 Belongs to the DEFL family Unknown Triticum aestivum (Wheat) Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43. No MICs found on DRAMP database Unknown 2226781 FEBS Lett. 1990 Sep 17;270(1-2):191-194. "Colilla FJ, Rocher A, Mendez E. " Gamma-Purothionins: amino acid sequence of two polypeptides of a new family of thionins from wheat endosperm. DRAMP00438 KSTCKAESNTFPGLCITKPPCRKACLSEKFTDGKCSKILRRCICYKPCVFDGKMIQTGAENLAEEAETLAAALLEEEMMDN 81 Defensin-like protein 1 (Gamma-thionin 1; Plant defensin) O24115 Belongs to the DEFL family THIO1 Nicotiana paniculata Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds 4-48; 15-35; 21-42; 25-44. No MICs found on DRAMP database Unknown PubMed ID is not available Plant Gene Register PGR97-132. "Komori T, Yamada S, Imaseki H." A cDNA clone for gamma-thionin from Nicotiana paniculata. DRAMP00439 RTCESQSHRFHGTCVRESNCASVCQTEGFIGGNCRAFRRRCFCTRNC 47 Defensin-like protein (Gamma-thionin homolog PPT; Plant defensin) Q40901 Belongs to the DEFL family Unknown Petunia integrifolia (Violet-flowered petunia) Antifungal Bridge Unknown Unknown "Function: May be involved in the defense of the pistil against pathogen infection. Tissue specificity: Predominantly expressed in the pistil during all stages of flower development. PTM: Contains four disulfide bonds 3-47; 14-34; 20-21; 24-43 (By similarity)." No MICs found on DRAMP database Unknown 7948892 Plant Mol Biol. 1994 Oct;26(1):459-464. "Karunanandaa B, Singh A, Kao TH." Characterization of a predominantly pistil-expressed gene encoding a gamma-thionin-like protein of Petunia inflata. DRAMP00440 NEMGGPLVVEARTCESQSHKFKGTCLSDTNCANVCHSERFSGGKCRGFRRRCFCTTHC 58 Defensin SD2 (Plant defensin) P82659 Belongs to the DEFL family SD2 Helianthus annuus (Common sunflower) Antifungal Bridge Unknown Unknown "Function:May play a protective role in flowers by protecting the reproductive organs from potential pathogen attack. Tissue specificity: Highest expression in flowers and to a lesser extent in leaves. Lower levels in hypocotyls. No expression in roots and cotyledons. Developmental stage:Expressed progressively during flower development reaching the highest level in the mature fertilized flower stage. PTM: Problely contains four disulfide bonds 14-57; 25-44; 31-52; 35-54." No MICs found on DRAMP database Unknown PubMed ID is not available Plant Physiol. Biochem. 2000;38:253-258. "Urdangarin M.C, de la Canal L." A defensin gene expressed in sunflower inflorescence. DRAMP00441 RTCQSQSHKFKGACFSDTNCDSVCRTENFPRGQCNQHHVERKCYCERDC 49 Defensin Tk-AMP-D1 (Plant defensin) P84963 Belongs to the DEFL family Unknown Triticum kiharae (Wheat) Antifungal Bridge Unknown Unknown "Function: Has weak antifungal activity, but not against A. consortiale Botrytis cinerea, H. sativum, F. culmorum, C. graminicola and D. maydis. PTM: Contains four disulfide bonds 3-49; 14-34; 20-43; 24-45 (By similarity)." Fungi: Fusarium graminearum and Fusarium verticillioides (MIC<30 ?g/ml). Unknown 17321030##18625284 Biochimie. 2007 May;89(5):605-612.##Biochimie. 2008 Nov-Dec;90(11-12):1667-1673. "Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV.##Odintsova TI, Rogozhin EA, Baranov Y, Musolyamov AKh, Yalpani N, Egorov TA, Grishin EV." Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes.##Seed defensins of barnyard grass Echinochloa crusgalli (L.) Beauv. DRAMP00442 RDCESDSHKFHGACFSDTNCANVCQTEGFTAGKCVGVQRHCHCTKDC 47 Defensin Tk-AMP-D1.1 (Plant defensin) P84965 Belongs to the DEFL family Unknown Triticum kiharae (Wheat) Antifungal Bridge Unknown Unknown "Function: Plant defense peptide (By similarity). PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)." No MICs found on DRAMP database Unknown 17321030 Biochimie. 2007 May;89(5):605-612. "Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV." Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. DRAMP00443 RTCESQSHKFKGPCFSDSNCATVCRTENFPRGQCNQHHVERKCYCERSC 49 Defensin Tk-AMP-D2 (Plant defensin) P84968 Belongs to the DEFL family Unknown Triticum kiharae (Wheat) Antifungal Bridge Unknown Unknown "Function: Plant defense peptide (By similarity). PTM: Contains four disulfide bonds 3-49; 14-34; 20-43; 24-45 (By similarity)." No MICs found on DRAMP database Unknown 17321030 Biochimie. 2007 May;89(5):605-612. "Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV." Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. DRAMP00444 RDCKSDSHKFHGACFSDTNCANVCQTEGFTRGKCDGIHCHCIKDC 45 Defensin Tk-AMP-D3 (Plant defensin) P84970 Belongs to the DEFL family Unknown Triticum kiharae (Wheat) Antifungal Bridge Unknown Unknown "Function: Plant defense peptide (By similarity). PTM: Contains four disulfide bonds 3-45; 14-34; 20-39; 24-41 (By similarity)." No MICs found on DRAMP database Unknown 17321030 Biochimie. 2007 May;89(5):605-612. "Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV." Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. DRAMP00445 RDCTSQSHKFVGLCLSDRNCASVCLTEYFTGGKCDHRRCVCTKGC 45 Defensin Tk-AMP-D4 (Plant defensin) P84971 Belongs to the DEFL family Unknown Triticum kiharae (Wheat) Antifungal Bridge Unknown Unknown "Function: Plant defense peptide (By similarity). PTM: Contains four disulfide bonds 3-45; 14-34; 20-39; 24-41 (By similarity)." No MICs found on DRAMP database Unknown 17321030 Biochimie. 2007 May;89(5):605-612. "Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV." Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. DRAMP00446 RECRSESKKFVGLCVSDTNCASVCLTERFPGGKCDGYRRCFCTKDC 46 Defensin Tk-AMP-D5 (Plant defensin) P84966 Belongs to the DEFL family Unknown Triticum kiharae (Wheat) Antifungal Bridge Unknown Unknown "Function: Plant defense peptide (By similarity). PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity). " No MICs found on DRAMP database Unknown 17321030 Biochimie. 2007 May;89(5):605-612. "Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV." Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. DRAMP00447 RDCRSQSKTFVGLCVSDTNCASVCLTEHFPGGKCDGYRRCFCTKDC 46 Defensin Tk-AMP-D6 (Plant defensin) P84967 Belongs to the DEFL family Unknown Triticum kiharae (Wheat) Antifungal Bridge Unknown Unknown "Function: Plant defense peptide (By similarity). PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity). " No MICs found on DRAMP database Unknown 17321030 Biochimie. 2007 May;89(5):605-612. "Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV." Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. DRAMP00448 RECRSQSKQFVGLCVSDTNCASVCLTEHFPGGKCDGYRRCFCTKDC 46 Defensin Tk-AMP-D6.1 (Plant defensin) P84969 Belongs to the DEFL family Unknown Triticum kiharae (Wheat) Antifungal Bridge Unknown Unknown "Function: Plant defense peptide (By similarity). PTM: Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity). " No MICs found on DRAMP database Unknown 17321030 Biochimie. 2007 May;89(5):605-612. "Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV." Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. DRAMP00449 RTCQSQSHKFKGACFSDTNCASVCRTENFPRGQCNQHHVERKCYCERDC 49 Defensin Tm-AMP-D1.2 (Plant defensin) P84964 Belongs to the DEFL family Unknown Triticum monococcum (Einkorn wheat) Antifungal Bridge Unknown Unknown "Function: Plant defense peptide (By similarity). PTM: Contains four disulfide bonds 3-49; 14-34; 20-43; 24-45 (By similarity)." No MICs found on DRAMP database Unknown 17321030 Biochimie. 2007 May;89(5):605-612. "Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV." Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes. DRAMP00451 QKLCARPSGTWSSGNCRNNNACRNFCIKLEKSRHGSCNIPFPSNKCICYFPC 52 Defensin-like protein 2B (AFP2b; M2B; Plant defensin) Q10989 Belongs to the DEFL family Unknown Sinapis alba (White mustard) Antifungal Bridge Unknown Unknown "Function: Possesses antifungal activity sensitive to inorganic cations. Subunit structure: Forms oligomers in its native state. PTM: Contains four disulfide bonds 4-52; 16-37; 22-46; 26-48 (By similarity)." No MICs found on DRAMP database Unknown 8836771 Int J Pept Protein Res. 1996 Jun;47(6):437-446. "Neumann GM, Condron R, Polya GM." Purification and mass spectrometry-based sequencing of yellow mustard (Sinapis alba L.) 6 kDa proteins. Identification as antifungal proteins. DRAMP00452 KICEALSGNFKGLCLSSRDCGNVCRREGFTDGSCIGFRLQCFCTKPCA 48 Defensin J1-1 (Plant defensin) Q43413 Belongs to the DEFL family Unknown Capsicum annuum (Bell pepper) Antifungal Bridge Unknown Unknown "Tissue specificity: Expressed in orange and red ripe fruit and to a lesser extent in mature, green fruit. Present in trace in young, green fruit. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43." "Fungi: Fusarium oxysporum, Botrytis cinerea." Unknown 8883377 Plant Physiol. 1996 Oct;112(2):615-622. "Meyer B, Houln?? G, Pozueta-Romero J, Schantz ML, Schantz R." Fruit-specific expression of a defensin-type gene family in bell pepper. Upregulation during ripening and upon wounding. DRAMP00453 RTCESQSHRFKGLCFSKSNCGSVCHTEGFNGGHCRGFRRRCFCTRHC 47 Defensin J1-2 (Plant defensin) O65740 Belongs to the DEFL family Unknown Capsicum annuum (Bell pepper) Antifungal Bridge Unknown Unknown "Tissue specificity: Expressed in flowers and in young fruits. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43." "Fungi: Fusarium oxysporum, Botrytis cinerea." Unknown 8883377##9790581 Plant Physiol. 1996 Oct;112(2):615-622.##Mol Gen Genet. 1998 Sep;259(5):504-510. "Meyer B, Houln?? G, Pozueta-Romero J, Schantz ML, Schantz R.##Houln?? G, Meyer B, Schantz R." Fruit-specific expression of a defensin-type gene family in bell pepper. Upregulation during ripening and upon wounding.##Alteration of the expression of a plant defensin gene by exon shuffling in bell pepper (Capsicum annuum L.). DRAMP00455 LLGRCKVKSNRFNGPCLTDTHCSTVCRGEGYKGGDCHGLRRRCMCLC 47 Defensin-like protein 2 (Fabatin-2; Plant defensin) P81457 Belongs to the DEFL family Unknown Vicia faba (Broad bean) Antibacterial Bridge Unknown Unknown "Function: Fabatins have antibacterial activity against Gram-positive and Gram-negative bacteria, but were inactive against the yeasts Saccharomyces cerevisiae and Candida albicans. High activity against P. aeruginosa. PTM: Contains four disulfide bonds 5-47; 16-36; 22-43; 26-45." "Gram-positive bacteria: Bacillus subtilis, Enterococcus hirae;##Gram-negative bacterium: Pseudomonas aeruginosa." Cell membrane 9103978 FEMS Microbiol Lett. 1997 Apr 1;149(1):59-64. "Zhang Y, Lewis K." Fabatins: new antimicrobial plant peptides. DRAMP00456 LLGRCKVKSNRFHGPCLTDTHCSTVCRGEGYKGGDCHGLRRRCMCLC 47 Defensin-like protein 1 (Fabatin-1; Plant defensin) P81456 Belongs to the DEFL family Unknown Vicia faba (Broad bean) Antibacterial Bridge Unknown Unknown "Function: Fabatins have antibacterial activity against Gram-positive and Gram-negative bacteria, but were inactive against the yeasts Saccharomyces cerevisiae and Candida albicans. High activity against P. aeruginosa. PTM: Contains four disulfide bonds 5-47; 16-36; 22-43; 26-45." "Gram-positive bacteria: Bacillus subtilis, Enterococcus hirae;##Gram-negative bacteria: Escherichia coli, Pseudomonas aeruginosa. " Cell membrane 9103978 FEMS Microbiol Lett. 1997 Apr 1;149(1):59-64. "Zhang Y, Lewis K." Fabatins: new antimicrobial plant peptides. DRAMP00457 RTCESKSHRFKGPCVSTHNCANVCHNEGFGGGKCRGFRRRCYCTRHC 47 Defensin-like protein 1 (LCR68; Plant defensin 2.3; Plant defensin) "Q9ZUL7, Q4VP02" Belongs to the DEFL family PDF2.3 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown "Tissue specificity: Expressed in the whole plant except roots. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43." No MICs found on DRAMP database Unknown 17147637 Plant Biotechnol J. 2006 May;4(3):317-324. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations. DRAMP00458 RTCESQSHRFKGTCVSASNCANVCHNEGFVGGNCRGFRRRCFCTRHC 47 Defensin-like protein 2 (LCR69; Plant defensin 2.2; Plant defensin) "Q39182, Q42011, Q4VP00, Q4VP03" Belongs to the DEFL family PDF2.2 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown "Function: Confers broad-spectrum resistance to pathogens. Tissue specificity: Broadly expressed. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)." No MICs found on DRAMP database Unknown 11437247##8281187 Plant Mol Biol. 2001 May;46(1):17-34.##Plant J. 1993 Dec;4(6):1051-1061.##Plant Physiol. Biochem. 1998;36:533-537. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##H??fte H, Desprez T, Amselem J, Chiapello H, Rouz?? P, Caboche M, Moisan A, Jourjon MF, Charpenteau JL, Berthomieu P, et al.##Thomma B.P.H.J, Broekaert W.F." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##An inventory of 1152 expressed sequence tags obtained by partial sequencing of cDNAs from Arabidopsis thaliana.##Tissue-specific expression of plant defensin genes PDF2.1 and PDF2.2 in Arabidopsis thaliana. DRAMP00459 RICKSRSQKFKGPCVSEDNCANVCHTEGFPDGDCDGLLRRCYCNTHC 47 Defensin-like protein 3 (Protein LCR71; Plant defensin) P82781 Belongs to the DEFL family LCR71 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds 3-47;14-34;20-41;24-43. No MICs found on DRAMP database Unknown 11437247 Plant Mol Biol. 2001 May;46(1):17-34. "Vanoosthuyse V, Miege C, Dumas C, Cock JM." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. DRAMP00460 RTCASQSQRFKGKCVSDTNCENVCHNEGFPGGDCRGFRRRCFCTRNC 47 Defensin-like protein 4 (Protein LCR70; Plant defensin 2.1; Plant defensin) "Q41914, Q541X5, Q9ZUL6" Belongs to the DEFL family PDF2.1 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown "Function: Confers broad-spectrum resistance to pathogens. Tissue specificity: Expressed in roots, siliques and seeds. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity)." No MICs found on DRAMP database Unknown 11437247##8281187 Plant Mol Biol. 2001 May;46(1):17-34.##Plant J. 1993 Dec;4(6):1051-1061. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##H??fte H, Desprez T, Amselem J, Chiapello H, Rouz?? P, Caboche M, Moisan A, Jourjon MF, Charpenteau JL, Berthomieu P, et al." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##An inventory of 1152 expressed sequence tags obtained by partial sequencing of cDNAs from Arabidopsis thaliana. DRAMP00461 RTCETSSNLFNGPCLSSSNCANVCHNEGFSDGDCRGFRRRCLCTRPC 47 Defensin-like protein 5 (Protein LCR66; Plant defensin 2.4; Plant defensin) "Q9C947, A0MED6, Q1PFI2, Q8LEG6" Belongs to the DEFL family PDF2.4 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown "PTM: Contains four disulfide bonds 4-51; 15-36; 21-45; 25-47, and Pyrrolidone carboxylic acid at position 1." No MICs found on DRAMP database Unknown 17147637 Plant Biotechnol J. 2006 May;4(3):317-324. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations. DRAMP00462 RTCQSKSHHFKYMCTSNHNCAIVCRNEGFSGGRCHGFHRRCYCTRLC 47 Defensin-like protein 6 (Protein LCR74; Plant defensin 2.5; Plant defensin) "Q9FFP8, P82783" Belongs to the DEFL family PDF2.5 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds 4-47; 14-34; 20-41; 24-43. No MICs found on DRAMP database Unknown 11437247 Plant Mol Biol. 2001 May;46(1):17-34. "Vanoosthuyse V, Miege C, Dumas C, Cock JM." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. DRAMP00463 QQMCEAKSLDWKGMCLKWRNCRQVCISEGFTDGRCKGFTRKCICSKPCFVLPN 53 Defensin-like protein 7 (Protein LCR75; LCR79; Plant defensin) "P82784, P82788" Belongs to the DEFL family LCR75 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown "Tissue specificity: Expressed in stems, roots, rosette leaves and flower buds. PTM: Contains four disulfide bonds 4-48;15-35;21-42;25-44." No MICs found on DRAMP database Unknown 11437247 Plant Mol Biol. 2001 May;46(1):17-34. "Vanoosthuyse V, Miege C, Dumas C, Cock JM." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. DRAMP00464 EVSPLDNKICKTRSDRFSGVCISTNNCAIICQQFEHFDGGHCEFDGAFRRCMCTKQC 57 Defensin-like protein 8 (Protein LCR73; Plant defensin) "P82782, Q4VP01" Belongs to the DEFL family LCR73 Arabidopsis thaliana (Mouse-ear cress) Unkonw Bridge Unknown Unknown PTM: Contains four disulfide bonds 10-57; 21-42; 27-51; 31-53. No MICs found on DRAMP database Unknown 11437247 Plant Mol Biol. 2001 May;46(1):17-34. "Vanoosthuyse V, Miege C, Dumas C, Cock JM." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. DRAMP00465 QPQLCETKSLNYRGLCLKWRSCKRVCISEGFPDGRCKGFFNNKCVCRKPCALLSTEN 57 Defensin-like protein 9 (Protein LCR76; Plant defensin) P82785 Belongs to the DEFL family LCR76 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds 5-50;16-36;22-44;26-46. No MICs found on DRAMP database Unknown 11437247 Plant Mol Biol. 2001 May;46(1):17-34. "Vanoosthuyse V, Miege C, Dumas C, Cock JM." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. DRAMP00466 RTCESPSNKFQGVCLNSQSCAKACPSEGFSGGRCSSLRCYCSKAC 45 Defensin-like protein 10 (Protein LCR72; Plant defensin 2.6; Plant defensin) "Q9ZUL8, Q0IGN8" Belongs to the DEFL family PDF2.6 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11437247 Plant Mol Biol. 2001 May;46(1):17-34. "Vanoosthuyse V, Miege C, Dumas C, Cock JM." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. DRAMP00467 QKCEWECKLLPNFPCWLKGAGEGLCDNLCKYEGAISGVCVSDPHRCLCRNRKPGCS 56 Defensin-like protein 11 (Plant defensin) "Q9M1V4, A0MF42" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 17147637##15955924 Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00468 QMNDCDCDHDHRCGEWEDESHGNCKQHHLRVVCTCTLDCLDISSTSNA 48 Putative defensin-like protein 12 (Plant defensin) Q2V477 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown "Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00469 QKLCERPSGTWSGVCGNSNACKNQCINLEKARHGSCNYVFPAHKCICYFPC 51 Defensin-like protein 13 (At-AFP1; Protein LCR67; Plant defensin) "P30224, Q42179" Belongs to the DEFL family PDF1.1 Arabidopsis thaliana (Mouse-ear cress) Antifungal Rich Unknown Unknown "Function: Confers broad-spectrum resistance to pathogens. Possesses antifungal activity sensitive to inorganic cations in vitro. Tissue specificity: Expressed predominantly in siliques and dry seeds. PTM: Contains four disulfide bonds 4-51; 15-36; 21-45; 25-47, and pyrrolidone carboxylic acid at Q1." "Fungi: Alternaria brassicola (IC50=10 ?g/ml), Botrytis cinerea (IC50=3.90 ?g/ml), Fusarium culmorum (IC50=3 ?g/ml), Fusarium oxysporum f.sp. lycopersici (IC50=3 ?g/ml), Pyricularia oryzae (IC50=0.25 ?g/ml), Verticiliium dahliae (IC50=1.50 ?g/ml)." Unknown 8422949##17180735##8989885 FEBS Lett. 1993 Feb 1;316(3):233-240.##Transgenic Res. 2007 Aug;16(4):531-538.##Plant Cell. 1996 Dec;8(12):2309-2323. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Sels J, Delaur?? SL, Aerts AM, Proost P, Cammue BP, De Bolle MF.##Penninckx IA, Eggermont K, Terras FR, Thomma BP, De Samblanx GW, Buchala A, M??traux JP, Manners JM, Broekaert WF." A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Use of a PTGS-MAR expression system for efficient in planta production of bioactive Arabidopsis thaliana plant defensins.##Pathogen-induced systemic activation of a plant defensin gene in Arabidopsis follows a salicylic acid-independent pathway. DRAMP00470 QKLCEKPSGTWSGVCGNSNACKNQCINLEGAKHGSCNYVFPAHKCICYFPC 51 Defensin-like protein 14 (Plant defensin 1.3; Plant defensin) O80995 Belongs to the DEFL family PDF1.3 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "PTM: Contains four disulfide bonds 4-51;15-36;21-45;25-47, and Pyrrolidone carboxylic acid at position 1." No MICs found on DRAMP database Unknown 10617197 Nature. 1999 Dec 16;402(6763):761-768. "Lin X, Kaul S, Rounsley S, Shea TP, Benito MI, Town CD, Fujii CY, Mason T, Bowman CL, Barnstead M, Feldblyum TV, Buell CR, Ketchum KA, Lee J, Ronning CM, Koo HL, Moffat KS, Cronin LA, Shen M, Pai G, Van Aken S, Umayam L, Tallon LJ, Gill JE, Adams MD, Carr" Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. DRAMP00471 QKLCEKPSGTWSGVCGNSNACKNQCINLEGAKHGSCNYVFPAHKCICYVPC 51 Defensin-like protein 15 (Putative plant defensin 1.2b; Plant defensin) O80994 Belongs to the DEFL family PDF1.2B Arabidopsis thaliana (Mouse-ear cress) Unkonw Unknown Unknown Unknown "Function: Confers broad-spectrum resistance to pathogens. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924##12447532 Plant Physiol. 2005 Jun;138(2):600-610.##Planta. 2002 Dec;216(2):193-202. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Thomma BP, Cammue BP, Thevissen K." Genome organization of more than 300 defensin-like genes in Arabidopsis.##Plant defensins. DRAMP00472 QKLCEKPSGTWSGVCGNSNACKNQCINLEGAKHGSCNYVFPAHKCICYVPC 51 Defensin-like protein 16 (LCR77; Defensin-like protein 15; Plant defensin) "Q9FI23, P82786, O80994" Belongs to the DEFL family PDF1.2A AND PDF1.2B Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown "Function: Confers broad-spectrum resistance to pathogens. Tissue specificity: Predominantly expressed in leaves. PTM: Contains four disulfide bonds 4-51;15-36;21-45;25-47, and Pyrrolidone carboxylic acid at position 1." Fungi: Alternaria brassicicola. Unknown 8989885##12447532 Plant Cell. 1996 Dec;8(12):2309-2323.##Planta. 2002 Dec;216(2):193-202. "Penninckx IA, Eggermont K, Terras FR, Thomma BP, De Samblanx GW, Buchala A, M??traux JP, Manners JM, Broekaert WF.##Thomma BP, Cammue BP, Thevissen K." Pathogen-induced systemic activation of a plant defensin gene in Arabidopsis follows a salicylic acid-independent pathway.##Plant defensins. DRAMP00473 QKLCEKPSGTWSGVCGNSNACKNQCINLEGAKHGSCNYVFPAHKCICYVPC 51 Defensin-like protein 17 (Plant defensin 1.2c; Plant defensin) Q9FI22 Belongs to the DEFL family PDF1.2C Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Confers broad-spectrum resistance to pathogens. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924##12447532 Plant Physiol. 2005 Jun;138(2):600-610.##Planta. 2002 Dec;216(2):193-202. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Thomma BP, Cammue BP, Thevissen K." Genome organization of more than 300 defensin-like genes in Arabidopsis.##Plant defensins. DRAMP00474 LCKRESETWSGRCVNDYQCRDHCINNDRGNDGYCAGGYPWYRSCFCFFSC 50 Defensin-like protein 18 (Plant defensin 1.5; Plant defensin) Q9FZ31 Belongs to the DEFL family PDF1.5 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Confers broad-spectrum resistance to pathogens. PTM: Contains four disulfide bonds 3-51; 14-35; 20-45; 24-47." No MICs found on DRAMP database Unknown 15955924##12447532 Plant Physiol. 2005 Jun;138(2):600-610.##Planta. 2002 Dec;216(2):193-202. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Thomma BP, Cammue BP, Thevissen K." Genome organization of more than 300 defensin-like genes in Arabidopsis.##Plant defensins. DRAMP00475 TEMMAVEGRICERRSKTWTGFCGNTRGCDSQCKRWERASHGACHAQFPGFACFCYFNC 58 Defensin-like protein 19 (Protein LCR78; Plant defensin 1.4; Plant defensin) "P82787, Q8VZQ7, Q9FWR6" Belongs to the DEFL family PDF1.4 Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds 11-58;22-43;28-52;32-54. No MICs found on DRAMP database Unknown 11437247 Plant Mol Biol. 2001 May;46(1):17-34. "Vanoosthuyse V, Miege C, Dumas C, Cock JM." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. DRAMP00476 QKHIAPWIFEDKSICCKEHPSVGRCLPGIDDDAEKDGKCWKFCIEGCETGGFCKLFEHKHICHCNCSG 68 Putative defensin-like protein 20 (Plant defensin) Q2V2S1 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00477 QKHTAPWIPEDNSICCKEHPSVGRCLPNIDDSAEKGGKCWKFCIEGCETGGFCKLFGHKHICHCNCSG 68 Defensin-like protein 21 (Plant defensin) "P0CAX9, O23285, Q2V3I6" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Bridge Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00478 YNVENGGSLCCNNHPKFGKCNTKNDDQRCNSWCLNGCDNGKGGYCKSMSHGGQCHCYC 58 Defensin-like protein 22 (Plant defensin) Q2V391 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00479 SGSSLCCNTHAKFGACNTYQDRKRCNKWCLDGCDNKKGGFCKRFAGGAKKCHCYC 55 Putative defensin-like protein 23 (Plant defensin) Q2V364 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00480 RKTVWPSSELDPKCCSNQPEFGICDSKEDDERCAQMCLDGCPTNKGGGCQPITEAPGAVCSCYCA 65 Defensin-like protein 24 (Plant defensin) Q2V371 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00481 YNVESGGSLCCNNHPKFGKCNTNNDNQRCNRWCHNGCGNGKGDYCKAMSHGGLCHCYC 58 Putative defensin-like protein 25 (Plant defensin) Q2V392 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00482 MIYNVESGGSLCCNSHPKFGKCNTNNDEQRCNRWCHNGCGNGKGGYYKSMSHGGQCHYYC 60 Putative defensin-like protein 26 (Plant defensin) Q2V4J2 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Problely contains two disulfide bonds. No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00483 VMNEDSILSSNKGDSLCCNDHPEFGICTNKSCNKWCLQGCTRGGFCKRKICHCYC 55 Putative defensin-like protein 27 (Plant defensin) Q2L6T3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00484 KENITPWIYSMKQPVSCNREHSEIGICLSGIDDDIQNDGKCWKFCLMVAKSGGYNADK 58 Putative defensin-like protein 28 (Plant defensin) "P0CAY0, F4JUP3, O23285" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00485 KSMVEVNAAHKWYIVEGLCSKFPDCNKHCKEQKFPGGTCLKLGVNMMCTCIYS 53 Putative defensin-like protein 29 (Plant defensin) Q2V3R9 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924##10907853 Plant Physiol. 2005 Jun;138(2):600-610.##DNA Res. 2000 Jun 30;7(3):217-221. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Kaneko T, Katoh T, Sato S, Nakamura A, Asamizu E, Tabata S." "Genome organization of more than 300 defensin-like genes in Arabidopsis.##Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones." DRAMP00486 KSMAKAQGGWYLVEGLCSKFPDCNKHCKEQGFLGGQCLKLGVNMLCFCIHT 51 Putative defensin-like protein 30 (Plant defensin) Q2V3S0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Caution: Could be the product of a pseudogene. Lacks the signal peptide, which is a conserved features of the family." No MICs found on DRAMP database Unknown 15955924##10907853 Plant Physiol. 2005 Jun;138(2):600-610.##DNA Res. 2000 Jun 30;7(3):217-221. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Kaneko T, Katoh T, Sato S, Nakamura A, Asamizu E, Tabata S." "Genome organization of more than 300 defensin-like genes in Arabidopsis.##Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones." DRAMP00487 EDRSKLIPIGPCSKIANCNQTCIESQFLGGKCIKWYPDSIKETCACLVKPSITHV 55 Putative defensin-like protein 31 (Plant defensin) Q2V3D7 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00488 KDIDGRKPLLIGTCIEFPTEKCNKTCIESNFAGGKCVHIGQSLDFVCVCFPKYYI 55 Defensin-like protein 32 (Plant defensin) Q2V4I8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00489 QNPRGRKCEDPNGVDQKAKCYIYCNEQGFLGGSCQGYTNHYMCECYVG 48 Putative defensin-like protein 33 (Plant defensin) Q2V4D6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00490 QILTGIKCPDPNGHDKEDKCNIYCLNQNYMGGSCQGYKNHYMCECYVG 48 Defensin-like protein 34 (Plant defensin) Q2V4D7 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00491 KSMNPTGRRCPDPNGVEKKSMCYSSCKTQGFMGGSCQGHKGNYMCECYEG 50 Defensin-like protein 35 (Plant defensin) "Q2V4F3, Q9SH70" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00492 IESPIFTGNKCSDPTGMDKDGKCLDYCHAQGYPGGSCIGFIDQGYMCVCKVG 52 Putative defensin-like protein 36 (Plant defensin) Q2V4D5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00493 TTAGRRDGKSGRTEWLYVAGECAKLPRCNKYCVSNGFHLGGFCEKLSPQASYLSCVCKYT 60 Defensin-like protein 37 (Plant defensin) "Q56XC2, F4JSA4, Q9SVQ4" Belongs to the DEFL family EDA21 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00494 YCERVRSRSAPHDICKKKNGNAVCKEKCWTIEKYQNGRCLILPKTTKLDCYCYHFDQC 58 Putative defensin-like protein 38 (Plant defensin) Q2V462 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00495 YCEKVRSKTAPRDVCKKSNGNALCKKTCWTIEKYVNGKCLILPKTTNLDCYCYHYDNGSACRA 63 Putative defensin-like protein 39 (Plant defensin) Q2V460 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00496 LGTSPYCEKVLSRFAPPGNCLKKNGNALCKESCANEQFREGVCLHLPKPQSKLNCYCSVLKCP 63 Putative defensin-like protein 40 (Plant defensin) Q2V325 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00497 MTQGKRKHPCDLKNPSKRAPPATCNKPNGAILCGDFCLHEGYNIGKCVMRRTGKACICSQCEGW 64 Defensin-like protein 41 (Plant defensin) Q3E8B0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00498 MNWELCDDYPSKAPPETCNKVDGARRCRTSCNNEGYGGANCNLKGKVKVCECTILRVCLPHHKRPPHVPKPPK 73 Putative defensin-like protein 42 (Plant defensin) P0CAY1 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "PTM: Contains four disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks the signal peptide, which is a conserved feature of the family." No MICs found on DRAMP database Unknown 15955924##10907853 Plant Physiol. 2005 Jun;138(2):600-610.##DNA Res. 2000 Jun 30;7(3):217-221. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Kaneko T, Katoh T, Sato S, Nakamura A, Asamizu E, Tabata S." "Genome organization of more than 300 defensin-like genes in Arabidopsis.##Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones." DRAMP00499 SEIKPTGRIDDQCKQMCSATYGDGKCASDCRKAGFSSGRCLTSSPFGNKCCCTK 54 Defensin-like protein 43 (Plant defensin) Q2V4J5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00500 SEIKPTGRVDNQCKEMCSATFGDGKCAADCRKAGFSSGRCLTSSPFGNKCCCT 53 Defensin-like protein 44 (Plant defensin) Q9M833 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00501 SDIKPTGRIDNQCKRMCSATYGNGKCAADCRSDGFSSGQCFTSPPFDNRCCCNN 54 Defensin-like protein 45 (Plant defensin) Q2V3Y8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00502 IDAGIKGFDTDHCDTRCYGRDECMNYCIKAGFPKGGQCGSLCIPCGFKCCCQK 53 Defensin-like protein 46 (Plant defensin) "Q2V3V1, A0ME04" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00503 SDARIEGFSFDNCNIRCSEDYWNDECNKDCLRAGFQKGGQCGSPCIPCPVKCCCQK 56 Defensin-like protein 47 (Plant defensin) Q3E7C7 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00504 AEIKKFSYDHCFHLCVAGEYGSNECFVDCAQKGFWHGDCANRTEKDPIRCCCYN 54 Putative defensin-like protein 48 (Plant defensin) Q2V365 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00505 AETTKFSYDHCFHLCVEGEYGSRECFVDCTQKGFWHGVCANKTTAKDPIHCCCYN 55 Defensin-like protein 49 (Plant defensin) Q2V366 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924##14993207 Plant Physiol. 2005 Jun;138(2):600-610.##Genome Res. 2004 Mar;14(3):406-413. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu??tier F, Scarpelli C, Sch?∟chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M." Genome organization of more than 300 defensin-like genes in Arabidopsis.##Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation. DRAMP00506 SEIKAKINGLECFNTCTPYYDDYKCNVDCLSSGYPAGDCHIVSPSQPKKCCCY 53 Defensin-like protein 50 (Protein LCR49; Plant defensin) P82764 Belongs to the DEFL family LCR49 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 17229318##11437247##15955924 BMC Genomics. 2007 Jan 17;8:18.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Moskal WA Jr, Wu HC, Underwood BA, Wang W, Town CD, Xiao Y.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Experimental validation of novel genes predicted in the un-annotated regions of the Arabidopsis genome.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00507 SEIKAKINGLECFNTCTSYYDDHKCNVDCLSSGYPAGECYTVSPSQPKKCCCY 53 Defensin-like protein 51 (Protein LCR48; Plant defensin) "P82763, A0MJW7, A7REH1" Belongs to the DEFL family LCR48 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 17565583##11437247##15955924 Plant J. 2007 Jul;51(2):262-280.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00508 VSGPPKCIALCRPGYYERFECFHDCITEGYDDGSCVPGPTTAKCGIITKTTNKICYSFAFE 61 Putative defensin-like protein 52 (Plant defensin) Q2V433 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "PTM: Problely contains two disulfide bonds. Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00509 MFSQNICMWRDCFARCSPGYYERFECFHDCITKGYDDGNCVPGPKTGRCCCTR 53 Putative defensin-like protein 53 (Plant defensin) P0CAY2 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "PTM: Contains four disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks the signal peptide, which is a conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00510 ESVIEPAKYGACLFLCDARRDDHACFYDCTNVAIYRTGHCVGNPPRCCCIRG 52 Defensin-like protein 54 (Plant defensin) Q8GY39 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11910074##15955924##14993207 Science. 2002 Apr 5;296(5565):141-145.##Plant Physiol. 2005 Jun;138(2):600-610.##Genome Res. 2004 Mar;14(3):406-413. "Seki M, Narusaka M, Kamiya A, Ishida J, Satou M, Sakurai T, Nakajima M, Enju A, Akiyama K, Oono Y, Muramatsu M, Hayashizaki Y, Kawai J, Carninci P, Itoh M, Ishii Y, Arakawa T, Shibata K, Shinagawa A, Shinozaki K.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu??tier F, Scarpelli C, Sch?∟chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M." Functional annotation of a full-length Arabidopsis cDNA collection.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation. DRAMP00511 LSNSDALASSVIETTKNDVCSTPCTIRYGTFECFQDCILDHFRDGNCINGRCCCKY 56 Putative defensin-like protein 55 (Plant defensin) Q2V2Q4 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00512 DVLASSDIYICVTVIETTKNDVCSTPCTIRYGTFECFHDCILEHYRDGNCINGRCCCK 58 Putative defensin-like protein 56 (Plant defensin) Q2V4A6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00513 SSVIETTKNDVCSTPCTRRYGTYECWHDCLHERYNDGGCVDGRCCCKK 48 Putative defensin-like protein 57 (Plant defensin) Q2V4A8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00514 DVLVSSVIETSKNDVCFIPCTRRYGDWECYDDCLGKNFNDGGCVDGRCCCKK 52 Defensin-like protein 58 (Plant defensin) "Q4VNZ9, F4IU82, F4IU83" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00515 LSNSDILVSSVIETSKYDVCFIPCTRRYEDRECNDDCLAKDFNDGGCVDGRCCCKY 56 Defensin-like protein 59 (Plant defensin) Q4VNZ8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00516 EVLVAPVIETAQNDVCFVPCTSRYGHYECAFDCMHKRYKDGGCVHGRCCCKT 52 Putative defensin-like protein 60 (Plant defensin) Q2V4A5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00517 YDRCIGPCLRFYGNHQCYKNCRKAKYDGGQCDFVKKGEKLPECCCYYNKN 50 Putative defensin-like protein 62 (Plant defensin) Q2V485 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00518 SYNIGQTRLVVIQEQEPHCIGPCEIAFGNRPCNEECTSQQYAYGFCDYQTKGEDNPQCCCYTS 63 Putative defensin-like protein 63 (Plant defensin) Q2V4G1 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00519 ERIDICFIPCTRRYGDYECWFDCTYNRYKEGGCVEDVVVKHNRNRPTFRAVELCFFSIKFMYDFSMK 67 Putative defensin-like protein 64 (Plant defensin) Q2V4A7 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00520 FSVQIGISVQAAPPTCGRDCTEKFLTQDCDKYCVGLSYKKGVCILSEGLPPKTSTYRCCCS 61 Putative defensin-like protein 66 (Plant defensin) Q2V2Y6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00521 VEMGISVQALPPTCGPDCTGRFMNQDCSKYCAALSYKHGVCILFRGLPPRTSTLRCCCG 59 Putative defensin-like protein 67 (Plant defensin) Q3EBU2 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00522 YDLFSEIGISAATLVIPTCFENCNATFQDPECNKWCALLAYKDGSCLYPPSEVDDLPPIKRPYIPRCCCNPITLSPPSP 79 Defensin-like protein 68 (Plant defensin) "Q2V4L5, A0MJT8, Q9LR89" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924##17147637##17229318 Plant Physiol. 2005 Jun;138(2):600-610.##Plant Biotechnol J. 2006 May;4(3):317-324.##BMC Genomics. 2007 Jan 17;8:18. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Moskal WA Jr, Wu HC, Underwood BA, Wang W, Town CD, Xiao Y." Genome organization of more than 300 defensin-like genes in Arabidopsis.##Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Experimental validation of novel genes predicted in the un-annotated regions of the Arabidopsis genome. DRAMP00523 YDLFTGIGIDARTVPPTCYESCNATFQNPECNKMCVGLAYKDGSCIYPPPEVDGLPPKRPYFPRCCCNPIILSPPSP 77 Defensin-like protein 69 (Plant defensin) "Q9FL73, A0MFP1" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 9679202##15955924##17147637 DNA Res. 1998 Apr 30;5(2):131-145.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant Biotechnol J. 2006 May;4(3):317-324. "Kaneko T, Kotani H, Nakamura Y, Sato S, Asamizu E, Miyajima N, Tabata S.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P." "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations." DRAMP00524 NFASGEASSQLCFNPCTPQLGNNECNTICMNKKYKEGSCVGFGIPPTSKYCCCKT 55 Putative defensin-like protein 70 (Protein LCR83; Plant defensin) P82792 Belongs to the DEFL family LCR83 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00525 LPSSVINGFGYDYCIVECSITFLDDACKPLCIDRGYSDGGCIGLSPHFKCCCKK 54 Defensin-like protein 71 (Plant defensin) P82793 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00526 MKLSILVKAMKRNNGFRYDYCIAECSEHFLDDVCKPVCIDKGYSDGGCIGLAPNFKCCCKK 61 Putative defensin-like protein 72 (Plant defensin) Q2V2S9 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "PTM: Contains four disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks the signal peptide, which is a conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00527 EPQCIGSCEMLADCNTACIRMGYLFGQCVGWKTPDMCCCNH 41 Putative defensin-like protein 73 (Protein LCR44; Plant defensin) P82759 Belongs to the DEFL family LCR44 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00528 QKECIGPCDMFTDCQAACVGIRKGYNYGQCVAWKPKDDDPFTCCCYKLTP 50 Defensin-like protein 74 (Protein LCR43; Plant defensin) P82758 Belongs to the DEFL family LCR43 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00529 ITVQADCIGPCNDDCQQLCKSKGYTDWTCASFRTKSSCCCKPPRHQIFEQNAQLNN 56 Defensin-like protein 75 (Protein LCR45; Plant defensin) P82760 Belongs to the DEFL family LCR45 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11437247 Plant Mol Biol. 2001 May;46(1):17-34. "Vanoosthuyse V, Miege C, Dumas C, Cock JM." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. DRAMP00530 IDVHDAMCYRSECTSVCDQICLSHGYTNGWYCGTFRLHTGCCCLKKKELNQIISPSKN 58 Defensin-like protein 76 (Protein LCR86; Plant defensin) P82795 Belongs to the DEFL family LCR86 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 10470850##11437247 DNA Res. 1999 Jun 30;6(3):183-195.##Plant Mol Biol. 2001 May;46(1):17-34. "Kaneko T, Katoh T, Sato S, Nakamura Y, Asamizu E, Kotani H, Miyajima N, Tabata S.##Vanoosthuyse V, Miege C, Dumas C, Cock JM." "Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence features of the regions of 1,011,550 bp covered by seventeen P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response." DRAMP00531 RSNGIYDPMCPGVCGNLVKPDCNGLCHELGFPAGGYCKPGNTCCCKKKDSGPVDVPPTA 59 Defensin-like protein 78 (Plant defensin) "Q9SL74, A0MJT1" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 17147637##15955924##17565583 Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants. DRAMP00532 YQMLICLDLNISCADCQKQCDETSYGGMCLNGGRTCCCKKSPPPSYYDPRPPSS 54 Putative defensin-like protein 79 (Plant defensin) Q2V470 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00533 EVRDICPGVCHAGIEPDCDTLCISMGFTGGYCQGLTCCCNPKSSKSSIINRPI 53 Putative defensin-like protein 80 (Protein LCR81; Plant defensin) P82790 Belongs to the DEFL family LCR81 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00534 KSPVSCDGACTSTPQCNKICTSKGYKKGICHGSAHLFYICCCYAKFESQYDPSISSPPNY 60 Defensin-like protein 81 (Plant defensin) Q2V4G6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 17147637##15955924##17565583 Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants. DRAMP00535 RTQEHPCQDYRLGCKSRDVCNAKCLSLGYVKGGDCVTFAFPICCCKINFGFQDDSPISSPIFTD 64 Defensin-like protein 82 (Plant defensin) Q2V334 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 14993207 Genome Res. 2004 Mar;14(3):406-413. "Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu??tier F, Scarpelli C, Sch?∟chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M." Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation. DRAMP00536 QIITCLPGECTNPSECNAACKSNGYKGGACVSMSIGSTTGACCCKPNFKSQDSFKSNDIIINNN 64 Putative defensin-like protein 83 (Protein LCR46; Plant defensin) P82761 Belongs to the DEFL family LCR46 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 10470850##11437247 DNA Res. 1999 Jun 30;6(3):183-195.##Plant Mol Biol. 2001 May;46(1):17-34 "Kaneko T, Katoh T, Sato S, Nakamura Y, Asamizu E, Kotani H, Miyajima N, Tabata S.##Vanoosthuyse V, Miege C, Dumas C, Cock JM." "Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence features of the regions of 1,011,550 bp covered by seventeen P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response." DRAMP00537 QSSKCTKGCTSTPECNIKCMKKGGGHCQAYIGRSHGRLAIENYCCCNNYSNSPISSPVMN 60 Putative defensin-like protein 84 (Plant defensin) Q2V2Y3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00538 LISDKCTEGCKSTIGCNTRCMMRGGGYCESAKIHGAVKIFCCCNNYSNSPISSPVIN 57 Defensin-like protein 85 (Plant defensin) Q8GXV6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11910074##9628582 Science. 2002 Apr 5;296(5565):141-145.##DNA Res. 1998 Feb 28;5(1):41-54. "Seki M, Narusaka M, Kamiya A, Ishida J, Satou M, Sakurai T, Nakajima M, Enju A, Akiyama K, Oono Y, Muramatsu M, Hayashizaki Y, Kawai J, Carninci P, Itoh M, Ishii Y, Arakawa T, Shibata K, Shinagawa A, Shinozaki K.##Sato S, Kaneko T, Kotani H, Nakamura Y, Asamizu E, Miyajima N, Tabata S." "Functional annotation of a full-length Arabidopsis cDNA collection.##Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence features of the regions of 1,456,315 bp covered by nineteen physically assigned P1 and TAC clones." DRAMP00539 QFRGIKQCEMKCYSTPECNATCLHEGYEEGKCLKSWDGGVECCCLGLLASSHQDSSPISSPHYIIFHGICILNI 74 Putative defensin-like protein 86 (Protein LCR82; Plant defensin) P82791 Belongs to the DEFL family LCR82 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown PTM: Contains four disulfide bonds (By similarity). No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00540 QLKSTCRIAEAWKGAKECNAKCAALGTTRGGVCQKFLGDLYCCCWD 46 Defensin-like protein 87 (Plant defensin) Q3E7S1 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Caution: Could be the product of a pseudogene. Lacks 1 of the 4 disulfide bonds, which are conserved features of the family. PTM: Contains three disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00541 VEVIPCIAGSKCTNDMTYNELCRFKGFSKGGFCQKYVHQTIGRCCCHPTGLESQESSISGDTNVVITN 68 Putative defensin-like protein 88 (Plant defensin) Q2V3J1 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00542 QTMQCYSGIACTDDGTCNDYCNPRNNNLGGVCLRRANCCCCYVSVVKSQESSLSKDTNNVFITN 64 Putative defensin-like protein 89 (Plant defensin) Q2V3J0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00543 SPEKYYDCKQDGCITTPPCWRKCVSMGYPKGGECRIYSYGGVCCCDLTSKPPN 53 Defensin-like protein 90 (Plant defensin) Q2V4G9 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00544 FTIAEPYIHPCMKGFCSFKSECANKCIFMGHHKGGDCIGGLDGIYCCCLA 50 Defensin-like protein 91 (Protein LCR47; Plant defensin) P82762 Belongs to the DEFL family LCR47 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 14993207##11437247##15955924 Genome Res. 2004 Mar;14(3):406-413.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu??tier F, Scarpelli C, Sch?∟chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00545 WGKCDLRKGLCRLADTISTCDVPCRAVDSKYHGGECLNVGGGQGICWCCRDYDAAKSGAEKESM 64 Defensin-like protein 95 (Plant defensin) "Q6NMS3, O49628" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00546 RQVCDYDKGECNSYEKSSTCIEPCKQLDSKFIGGRCIPVGGITGMGLCVCCRDVQRGAEKESM 63 Defensin-like protein 96 (Plant defensin) "Q8L7G7, O49628, Q8H0Y6" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Confers broad-spectrum resistance to pathogens. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00547 RRVCDSAAGLCSMLFSCNTQCNSLGRNFTGGECSDARFPGLSVCYCCHNVESSAEMESM 59 Defensin-like protein 97 (Protein LCR85; Plant defensin) "P82794, O49626, Q1PE59" Belongs to the DEFL family LCR85 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 17147637##15955924##17565583 Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants. DRAMP00548 RLVCDTPAGTCTSSSTCNDQCNTWGGNYSGGECADSSFPGLSICYCCHYVGSSAEMESM 59 Defensin-like protein 98 (Plant defensin) "Q94AZ8, O49626" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00549 SCDFPLGACTPFRDCKESCIKFKTRAGQTFFDGKCRPRDRPSVWTACFCCYYDSIGAQ 58 Defensin-like protein 100 (Plant defensin) "Q3E6U0, A0MJT5, O49626" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 17147637##15955924##17565583 Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants. DRAMP00550 FPASDQSIYARCIGPCPRYAVPHWCENECLSRKYMAGGECAFIEGEGPTPRCCCINL 57 Putative defensin-like protein 101 (Plant defensin) Q2V337 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00551 RTTTGGSPGYGIGGRTKTCFTPALCIYRGVHGCDSYCKTKNFDYGYCRQEHCCCVNY 57 Putative defensin-like protein 102 (Plant defensin) Q2V3L0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00552 LPTTARSPGYEIGPQRRRRVTCFSFSFCKPARGLASCDLFCKRLKFESGLCTGDLEKCCCIDYIN 65 Defensin-like protein 103 (Plant defensin) Q8GXR4 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11910074##15955924 Science. 2002 Apr 5;296(5565):141-145.##Plant Physiol. 2005 Jun;138(2):600-610. "Seki M, Narusaka M, Kamiya A, Ishida J, Satou M, Sakurai T, Nakajima M, Enju A, Akiyama K, Oono Y, Muramatsu M, Hayashizaki Y, Kawai J, Carninci P, Itoh M, Ishii Y, Arakawa T, Shibata K, Shinagawa A, Shinozaki K.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Functional annotation of a full-length Arabidopsis cDNA collection.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00553 LPMTHGGKPGYGIERTIIRPEWRCYVDEGCPKGQGAPCEKNCKNVADYGICIGIKCCCFDVIPVPPT 67 Putative defensin-like protein 104 (Plant defensin) Q2V476 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00554 MLMACYSAGQLGCLVFCNEAEYSYGKCIGRGRCCCYDL 38 Putative defensin-like protein 105 (Plant defensin) P0CAY3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00555 HTTIASAPSSGEPTTYATGPALSKHSHDNDGICFVTPACFAPGQYEIGCIVYCHESHYKHYKCVNRSCCCYNTDKNASELK 81 Defensin-like protein 106 (Plant defensin) "Q1G3Y1, A0MDJ9, Q9SYA4" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 17147637##15955924##17565583 Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants. DRAMP00556 RMTTTTSPGFGIKQQDRQCFEHAPYLCRGGEGDCRMYCRDLDFSFGTCFSGVCCCQI 57 Defensin-like protein 107 (Plant defensin) Q2V413 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00557 RMTTASTPGYGIKQEDRLCIQGQEGTKLCSSGTSRDCLNFCLIRGYAGGSCYAYTLDQCCCRIPPPKLK 69 Defensin-like protein 108 (Protein LCR51; Plant defensin) "A8MQN0, O80684" Belongs to the DEFL family LCR51 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00558 RPSFKPIPLFGEKLTQCFDTRPCLQGMLKCIEFCSSMGTADGQCNNENLCCCTHE 55 Defensin-like protein 109 (Plant defensin) Q2V390 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 9679202##15955924 DNA Res. 1998 Apr 30;5(2):131-145.##Plant Physiol. 2005 Jun;138(2):600-610. "Kaneko T, Kotani H, Nakamura Y, Sato S, Asamizu E, Miyajima N, Tabata S.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Genome organization of more than 300 defensin-like genes in Arabidopsis." DRAMP00559 RSTSDIVSGSGIKEDEHVCFKTSPCLPEVGGEKGCIAFCSRMKFTTGLCLGSVVCCCYT 59 Putative defensin-like protein 110 (Plant defensin) Q2V4N0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00560 SDDTQGFGIKQEYKQCYTPDPCRKGGNDECERFCVAKSGLLYGKCINDGSKDVCCCLTK 59 Putative defensin-like protein 111 (Protein LCR50; Plant defensin) P82765 Belongs to the DEFL family LCR50 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00561 SDRTSGVGINQEYAKCYDLADCQKPKVDDAACERFCGAKSFLLYGKCDTATNKCCCKSKTK 61 Defensin-like protein 112 (Plant defensin) Q2V488 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00562 SDSFPGLGLKKQAHKQCYSPDLCTGGDSKCDICCVLISGVYYGKCIQSKCHCLNKTK 57 Defensin-like protein 113 (Plant defensin) Q2V342 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00563 SELDNTSGFEIKQEDKCYGPEPCKNGYEGCLFFCVRIAYYLYGECTMKPDHQKHCCCVTK 60 Putative defensin-like protein 114 (Plant defensin) Q2V322 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00564 SDSTLGIGINQDWKKCFSPDPCKKAGTQGCMEFCRTISFLLFGECTSKPDQCCCVTK 57 Defensin-like protein 115 (Plant defensin) Q2V321 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00565 SDSALGIGIKEDWEVCFSIDPCLTGEGTLGCTKWCRNHINLSLVGYCRTDPEHCCCVAEK 60 Defensin-like protein 116 (Plant defensin) Q3E8I8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 9679202##15955924##14993207 DNA Res. 1998 Apr 30;5(2):131-145.##Plant Physiol. 2005 Jun;138(2):600-610.##Genome Res. 2004 Mar;14(3):406-413. "Kaneko T, Kotani H, Nakamura Y, Sato S, Asamizu E, Miyajima N, Tabata S.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Castelli V, Aury JM, Jaillon O, Wincker P, Clepet C, Menard M, Cruaud C, Qu??tier F, Scarpelli C, Sch?∟chter V, Temple G, Caboche M, Weissenbach J, Salanoubat M." "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Whole genome sequence comparisons and full-length cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation." DRAMP00566 SDGTSGYGITEATKRCFTPAPCTRGLFYCQTFCSSLSAVLIGVCESGICCCILNQ 55 Defensin-like protein 117 (Plant defensin) Q2V4G3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 17147637##15955924##17565583 Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants. DRAMP00567 QEMCRDILMKAKNCDEGTCDTLCKQKWKGNGSCFPNVYTYRKSCLCTFPCKT 52 Putative defensin-like protein 118 (Protein LCR52; Plant defensin) P82766 Belongs to the DEFL family LCR52 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00568 QEMCRDLLMRAKNCDDSTCATLCKQKWKGNGSCFPNVYRKSCLCTFPCKT 50 Putative defensin-like protein 119 (Protein LCR53; Plant defensin) P82767 Belongs to the DEFL family LCR53 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00569 QEMCHDLIKKTDCDDATCVTLCKQKWNGNGGGSCFQIVNLKSCLCAFPCQV 51 Putative defensin-like protein 120 (Protein LCR56; Plant defensin) P82770 Belongs to the DEFL family LCR56 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00570 QETCHDLIMKRDCDEATCVNMCQQKWKGSGGSCFQNFNVMSCICNFPCQV 50 Putative defensin-like protein 121 (Protein LCR55; Plant defensin) P82769 Belongs to the DEFL family LCR55 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00571 QELCHDYMSGTELCEEDKCVAKCIWMHGTAAKGTCMPKPSKQCVCTYSCNA 51 Defensin-like protein 122 (Protein LCR30; Plant defensin) P82745 Belongs to the DEFL family LCR30 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. Tissue specificity: Expressed in flower buds, but not in stems, roots or rosette leaves. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00572 MRPRSRAGDKFMSQGQELCHEYFQLTAPCEKQPCIDMCSSKYKTGKGVCGPAVHQCFCTFSCTV 64 Defensin-like protein 123 (Plant defensin; Uncertain) Q0WN71 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924##17565583 Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants. DRAMP00573 ANCVNYFEITFPEVCEANWCAAECLKAYKNGKGTCWQKFCQCVYDC 46 Defensin-like protein 124 (Protein LCR16; Plant defensin) "P82731, A0MJV4" Belongs to the DEFL family LCR16 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 17147637##15955924##17565583 Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants. DRAMP00574 EEKQCYDYLLTPQENCEGLICAHECTMQHGGNGVCVDTTSTVCICTYDCTS 51 Defensin-like protein 125 (Protein LCR54; Plant defensin) P82768 Belongs to the DEFL family LCR54 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00575 QHAMCHEILPETDCGAGSCTALCLQLWRGTGKCVRTNDQKLICLCNFECIV 51 Putative defensin-like protein 126 (Protein LCR6; Plant defensin) P82721 Belongs to the DEFL family LCR6 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 9679202##11437247##15955924 DNA Res. 1998 Apr 30;5(2):131-145.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis." DRAMP00576 QNAICQKFLSETDCGAGSCTALCLQLWKGIGKCIKTDDHKLLCLCKYECIV 51 Defensin-like protein 127 (Protein LCR20; Plant defensin) "P82734, Q4VP05, Q4VP06" Belongs to the DEFL family LCR20 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 9679202##11437247##15955924 DNA Res. 1998 Apr 30;5(2):131-145.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis." DRAMP00577 QHICHQILLNNNCDGATCTSLCDKQLQGTGQCYKTVDKRFICLCNYLCRT 50 Putative defensin-like protein 128 (Protein LCR8; Plant defensin) P82723 Belongs to the DEFL family LCR8 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00578 DTCHEYLYPEKCENNQCNSECATKFKEVGVFGFCVPPRSEPTEQFCICSYNC 52 Putative defensin-like protein 129 (Protein LCR13; Plant defensin) P82728 Belongs to the DEFL family LCR13 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00579 SIFIKYSDRTCHVYIKAENCEIDQCNWECGTKYKRVGVQGLCVPPGFDPIDQACLCSFNC 60 Defensin-like protein 130 (Protein LCR28; Plant defensin) "P82743, Q2V320" Belongs to the DEFL family LCR28 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 9679202##11437247##15955924 DNA Res. 1998 Apr 30;5(2):131-145.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis." DRAMP00580 HICHDYLEGDHCDPKDCNLDCRDKWKGTGTCEPPTGTPLTRTCYCTYDC 49 Putative defensin-like protein 131 (Protein LCR29; Plant defensin) P82744 Belongs to the DEFL family LCR29 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00581 NDEQLRGNRCFQIKFKTGKCVPKECQTACQEKLRKPKLKGEGFCMKECTCCFYT 54 Putative defensin-like protein 133 (Protein LCR33; Plant defensin) P82748 Belongs to the DEFL family LCR33 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00582 FSPEDCLDDVGWILICTKPTCKFSCWTSRSVNKGRKMQDYWCSDSNTCHCVFCTGD 56 Putative defensin-like protein 134 (Plant defensin) P0CAY4 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00583 QRRKCDEKIVLQFCNGRNRCYEYCDTKECVAACKKKRNGEGICNGDVFSVSAQCLCLYKC 60 Putative defensin-like protein 135 (Plant defensin) Q2V3K1 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00584 NMSVDQKRCWATLKENNCVHDECRSMCLKKNPKGHGRCIKSSKGRIICLCGYDCP 55 Putative defensin-like protein 137 (Protein LCR14; Plant defensin) P82729 Belongs to the DEFL family LCR14 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00585 QPLGTMERCYDMLTWGECVPDNCAFSCALKRHGKGGCIKAYDNRPACVCYYTCLRS 56 Putative defensin-like protein 139 (Protein LCR7; Plant defensin) P82722 Belongs to the DEFL family LCR7 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00586 QPLEEMVECKEVLWPEECKYDACAFACALKRHGKGGCLEGPDYRSACICQYACKRS 56 Defensin-like protein 140 (Protein LCR15; Plant defensin) P82730 Belongs to the DEFL family LCR15 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00587 QQQQQRCEEALTEIDCGAGNCNALCLQKRKGLGRCVQRTPCDKLKCMCYYPCSS 54 Defensin-like protein 141 (Protein LCR3; Plant defensin) P82718 Belongs to the DEFL family LCR3 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 9679202##11437247##15955924 DNA Res. 1998 Apr 30;5(2):131-145.##Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis." DRAMP00588 EKLTTCSRFLSQKSGKCVKEDCDRMCKQKWPGKYTVGHCYGQFKDAKRCLCSVCGPDRQPP 61 Putative defensin-like protein 142 (Protein LCR34; Plant defensin) P82749 Belongs to the DEFL family LCR34 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00589 MVNGQCSFPQPVGPNGKCVPKDCKSLCHKKYKGGSICTTGKPNICMCLVCRRRSPEV 57 Defensin-like protein 144 (Protein LCR10; Plant defensin) "Q8S8H9, A0MJT0, P82725, Q1PF66" Belongs to the DEFL family LCR10 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 17147637##15955924##17565583##11437247 Plant Biotechnol J. 2006 May;4(3):317-324.##Plant Physiol. 2005 Jun;138(2):600-610.##Plant J. 2007 Jul;51(2):262-280.##Plant Mol Biol. 2001 May;46(1):17-34. "Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA.##Vanoosthuyse V, Miege C, Dumas C, Cock JM." Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.##Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. DRAMP00590 NLQQRRQMNQTWCSRPLLTHKQTGKCVIEDCESKCRQKWKGNGTQATCRNQCNCHFRCPWIQGQP 65 Putative defensin-like protein 145 (Protein LCR2; Plant defensin) P82717 Belongs to the DEFL family LCR2 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00591 NVQQVKREQCHTVIPNKSGKCIFTECKSACEKLKKPVASLCLPPKTCRCYHFCS 54 Putative defensin-like protein 146 (Protein LCR9; Plant defensin) P82724 Belongs to the DEFL family LCR9 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00592 NVQQKRSNRCIDFPVNPKTGLCVLKDCESVCKKTSKGLEGICWKFNAKGKDPKQCKCCGLWPPLY 65 Defensin-like protein 147 (Protein LCR1; Plant defensin) P82716 Belongs to the DEFL family LCR1 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00593 NVEQKSQDWCWSIVNKDRCLQKECESLCSKKHPKGKFMCIPSTPGGPFQCHCRHPCR 57 Putative defensin-like protein 148 (Protein LCR4; Plant defensin) P82719 Belongs to the DEFL family LCR4 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00594 NEGLGKPKKQCNEILKQSNCVAAECDSMCVKKRGKGAGYCSPSKKCYCYYHCP 53 Defensin-like protein 149 (Protein LCR5; Plant defensin) "Q8S8H3, P82720, Q8LGD4" Belongs to the DEFL family LCR5 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00595 DVDQGYKQQCYKTIDVNLCVTGECKKMCVRRFKQAAGMCIKSVPSAPAPNRCRCIYHC 58 Putative defensin-like protein 150 (Protein LCR32; Plant defensin) P82747 Belongs to the DEFL family LCR32 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00596 QAPSTCFEALKDASKGASCDSELCASLCKKKSGGGVGTCRTKTTQPSKGQPECHCRFWCKSDGTPYK 67 Defensin-like protein 151 (Protein LCR17; Plant defensin) "Q9T0E3, Q6GKX9" Belongs to the DEFL family LCR17 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00597 KQRLCIKVLTNASHVSKGASTCDSKLCTSLCEKISPQGVSFCKPIATTGQSKKGNPVCNCRYWCRSDGTPHTT 73 Putative defensin-like protein 152 (Protein LCR11; Plant defensin) P82726 Belongs to the DEFL family LCR11 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00598 KVPCLSRMFNKNNTCSFLRCEANCARKYKGYGDCRPGDRPHDKKDSLFCFCNYPC 55 Defensin-like protein 153 (Protein LCR31; Plant defensin) "P82746, A0MJV0" Belongs to the DEFL family LCR31 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00599 VVEKAKGDGSCTIIIDPKAPSCDIIQCRLSCITDYNGLAECIASRIGSPPNCVCTYDC 58 Putative defensin-like protein 154 (Protein LCR35; Plant defensin) P82750 Belongs to the DEFL family LCR35 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00600 DKRCSIIIDLSPCYPIECRLSCITERNGDGECVVSKVGSTPNCLCTYDC 49 Defensin-like protein 155 (Protein LCR36; Plant defensin) P82751 Belongs to the DEFL family LCR36 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00601 KRHCSTIILPESPCVPQDCVEYCFEEYNGGGTCIASKTGRTTNCMCTYNCHGNNL 55 Defensin-like protein 156 (Protein LCR21; Plant defensin) P82735 Belongs to the DEFL family LCR21 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00602 DERCTIIIHPGSPCDPSDCVQYCYAEYNGVGKCIASKPGRSANCMCTYNC 50 Putative defensin-like protein 157 (Protein LCR22; Plant defensin) Q9M0F3 Belongs to the DEFL family LCR22 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00603 DQTDKYCTIIIDPRTPCDLVDCRLSCYTGYNGVGKCIASKASRTPNCVCTYNC 53 Putative defensin-like protein 158 (Protein LCR23; Plant defensin) P82737 Belongs to the DEFL family LCR23 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00604 KRCHLTIDKATACSLSDCRLSCYSGYNGVGKCFDDPKVAGPSNCGCIYNC 50 Defensin-like protein 159 (Protein LCR25; Plant defensin) "P82739, A0MJW9" Belongs to the DEFL family LCR25 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00605 DEGKRCHTTIDKGNFCDLVDCRLSCFSGYNGVGKCFDDPKVPGRSNCGCLYNC 53 Putative defensin-like protein 160 (Protein LCR26; Plant defensin) Q9M0F2 Belongs to the DEFL family LCR26 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00606 EECRLTIDKATPCHLSDCRLSCYTGYNGVGECFDDPNVPGPDNCGCRYNC 50 Defensin-like protein 161 (Protein LCR27; Plant defensin) Q9M0F1 Belongs to the DEFL family LCR27 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00607 GATIKKCVVDVKLSKPCTFQECQPLCLQKYNGNGLCPGDDNNICACVYNC 50 Putative defensin-like protein 162 (Protein LCR37; Plant defensin) P82752 Belongs to the DEFL family LCR37 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00608 ADIKRCVVDVKLSKPCTFQECIPLCFQRYNGNGVCTGKKNEICTCAYNC 49 Defensin-like protein 163 (Protein LCR24; Plant defensin) "Q8LFM0, P82738, Q0V821" Belongs to the DEFL family LCR24 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00609 KQLKTCTSVIKLGHPCDIESCLNECFRVYNTGFATCRGDKYSQLCTCEYNC 51 Defensin-like protein 164 (Protein LCR38; Plant defensin) P82753 Belongs to the DEFL family LCR38 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00610 QKRCRQELEPGKQCVLAKCRELCFKQLKGFGSCIEKPPGSSKYTCNCFYNCGPPGFF 57 Putative defensin-like protein 165 (Protein LCR12; Plant defensin) P82727 Belongs to the DEFL family LCR12 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00611 LYMCVSSTCVIQWCAIQCKRKEANGIGTCKPRPNQGKIQYRKLKEECHCVYKCS 54 Defensin-like protein 166 (Plant defensin) P0CAY5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00612 RNRICRTSEKYYREFCGHAGNDDCLSKSTKKPKPFKCVCHDNRSQNITSINDRYNNCICTFYC 63 Putative defensin-like protein 168 (Plant defensin) Q2V3Q1 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00613 LMDSMPQRHPVEGWCKRPLPNQKPGPCNNDRCSARCKEQKQFEFKGGKAMGICSSENRCLCTFRCR 66 Putative defensin-like protein 169 (Plant defensin) Q2V3K0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00614 NMGCMAVLGSCGVITDCSGSCKTKFGQDASGDCDRDGGQGTCMCGYPCPHDKLHM 55 Putative defensin-like protein 170 (Protein LCR62; Plant defensin) P82776 Belongs to the DEFL family LCR62 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00615 NMGCMAVLGSCGVITDCSGECISRFGPQARGYCDRDGGSGTCVCVYPCPADKPHM 55 Defensin-like protein 171 (Protein LCR61; Plant defensin) "P82775, Q4VNZ4" Belongs to the DEFL family LCR61 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00616 NMGCTATMGPCEKDKSCSATCRATFGDRANGFCDYSTSTSPGGECTCVYHCPPVVPHESHL 61 Defensin-like protein 172 (Protein LCR60; Plant defensin) P82774 Belongs to the DEFL family LCR60 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00617 NMGCIQIIGRCIKIPDCSASCRKFLGPHASGYCDNDGAGGTCICTYPCQTKEIHM 55 Defensin-like protein 173 (Protein LCR63; Plant defensin) "P82777, Q4VNZ3" Belongs to the DEFL family LCR63 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00618 NTGCFDYDVYQPCDHCRERCLKYYPVTRKAICRKNHCVCIGPCPNDKAIPNVKLFKNVKEQILS 64 Defensin-like protein 175 (Plant defensin) Q2V4H7 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00619 NTGCFDYDVYQPCDHCRERCLKYYPVTRKAICRKNHCVCIGPCPDDKAIPDVKLFKNVKEQILS 64 Defensin-like protein 176 (Protein LCR65; Plant defensin) "P82779, A0MJW1" Belongs to the DEFL family LCR65 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00620 NMGCNDYIVGDVCVHCRERCLRYYPVTRKAECYRNHCLCIGPCPDDRPHKRFQMLNSSKNVKAQILS 67 Defensin-like protein 178 (Protein LCR64; Plant defensin) "P82778, A0MJW0" Belongs to the DEFL family LCR64 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00621 QTCDENLSSCENCDQRCKAKHGPSSVSKCNGPDGTCGCASFKPAKLCIGATDMCTDKCPTSCCDRQCAIKYKNGKGGCVDYAGYRMCICEYTC 93 Putative defensin-like protein 179 (Protein LCR57; Plant defensin) P82771 Belongs to the DEFL family LCR57 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains seven disulfide bonds (By similarity). Caution: Contains 7 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00622 SICNDRLGLCDGCDQRCKAKHGPSCESKCDGPVGMLLCTCTYECGPTKLCNGGLGNCGESCNEQCCDRNCAQRYNGGHGYCNTLDDFSLCLCKYPC 96 Defensin-like protein 181 (Protein LCR80; Plant defensin 3.1; Plant defensin) "P82789, A0MJT6, Q1PDQ7" Belongs to the DEFL family PDF3.1 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Confers broad-spectrum resistance to pathogens. PTM: Contains eight disulfide bonds (By similarity). Caution: Contains 8 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00623 NTCIEGIGNCQQCDVRCKARHGPAAKGACDSKFQLCTCNYPCGQGPSPPQPKKCYGGAGICSDRCGAQCCNQNCAQKYNQGSGFCDSIGNTSLCKCQYNC 100 Defensin-like protein 183 (Protein LCR19; Plant defensin) "P82733, Q4VNZ2" Belongs to the DEFL family LCR19 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains eight disulfide bonds (By similarity). Caution: Contains 8 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00624 NKKMVGEAKKCDQTWTCEGEDKCREKCLTLHNGVGVCDLYTAPLVPKQCFCHYDC 55 Putative defensin-like protein 184 (Protein LCR18; Plant defensin) P82732 Belongs to the DEFL family LCR18 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00625 KTCSDGWTCLGPKEEDKCKENCMAKHKGVGTCNLYTIPEFPAPITYYMCDCMFDC 55 Putative defensin-like protein 185 (Protein LCR39; Plant defensin) P82754 Belongs to the DEFL family LCR39 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00626 KTCSDGWTCVGEDKCKVNCMAKHKGVGTCTLYIIPSFPAPITSYICDCMFDC 52 Putative defensin-like protein 186 (Protein LCR40; Plant defensin) P82755 Belongs to the DEFL family LCR40 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00627 ENQKMVGEAKQCKTGWACFGEDACKEKCMAKYKGVGTVTYFPFPPETIIIYCECLYDC 58 Putative defensin-like protein 187 (Protein LCR42; Plant defensin) P82757 Belongs to the DEFL family LCR42 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00628 ENGIMIGEAKKCSNSWICEGDEKCKEKCMADYKGNGTCYYPSPPSKQHPEFFYPTCWCGFDC 62 Putative defensin-like protein 188 (Protein LCR41; Plant defensin) P82756 Belongs to the DEFL family LCR41 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00629 MSNGMPRTVPCIEGRILWNRTLPCSSILCGDHCVPHGYRAGTCDIVNDRAICKCSRCR 58 Putative defensin-like protein 189 (Plant defensin) Q2V468 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00630 MRMTQKVSCIEGRTLWARPPKFFYCSSTLCEDNCINTGAYRGGTCDMEDEVAICRCHRCKKII 63 Putative defensin-like protein 190 (Plant defensin) Q2V467 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00631 KKPPCLEGRTAYVSPGPCSNSLCTQDCRPAGYHTGKCKVEWSTPICKCYGCRKV 54 Putative defensin-like protein 191 (Plant defensin) Q2V466 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00632 YDRKCLKEYGGDVGFSYCAPRIFPTFCDQNCRKNKGAKGGVCRWEENNAIGVKCLCNFCSEEPSDQTLSRI 71 Defensin-like protein 192 (Trypsin inhibitor ATTI-7; Plant defensin) "Q42330, Q9SX84" Belongs to the DEFL family O22866 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00633 QGSKCLKEYGGNVGFSYCAPRIFPSFCYRNCRKNKGAKGGRCRSGGAGAGSMICLCDYCSDKP 63 Defensin-like protein 193 (Trypsin inhibitor ATTI-2; Plant defensin) "O22866, Q67YC6, Q6ZZT9" Belongs to the DEFL family ATTI2 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00634 KDKECLKGYIDAPLSYCMARIYPSLCYRNCRFYKGAKGGKCDGLKCFCDFCSDKPF 56 Defensin-like protein 194 (Trypsin inhibitor ATTI-3; Plant defensin) "O22867, B9DGH7, F4IR67, Q6ZZP9, Q6ZZQ4, Q6ZZQ9, Q6ZZR4, Q6ZZR9, Q6ZZT8" Belongs to the DEFL family ATTI3 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00635 QGNECLKEYGGDVGFGFCAPRIFPTICYTRCRENKGAKGGRCRWGQGSNVKCLCDFCDDTPQ 62 Defensin-like protein 195 (Trypsin inhibitor ATTI-1; diDi 4T-1; Plant defensin) "Q42328, O22865, Q6ZZP6" Belongs to the DEFL family ATTI1 Arabidopsis thaliana (Mouse-ear cress) Antifungal Combine helix and strand structure "The protein contains one alpha-helix and two strands of antiparallel beta-sheet, with a type IV beta-turn connecting the two strands. The alpha-helix and the inhibitory loop are connected to the beta-sheet through three disulfide bridges; a fourth disulfide bridge connects the N- and C-termini. (Ref.3)" 1JXC resolved by NMR. "Function: Defense response to fungus. PTM: Contains four disulfide bonds." No MICs found on DRAMP database Unknown 11437247##15955924##12369816 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610.##Biochemistry. 2002 Oct 15;41(41):12284-96. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA.##Zhao Q, Chae YK, Markley JL." "Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis.##NMR solution structure of ATTp, an Arabidopsis thaliana trypsin inhibitor." DRAMP00636 HDSECLKEYGGDVGFGFCAPKIFPTICYRNCQKDKGANGGKCLWGEGGKVKCLCDFCSNESFNQFISLT 69 Defensin-like protein 196 (Trypsin inhibitor ATTI-4; Plant defensin) "Q8RYE7, Q6ZZS3" Belongs to the DEFL family ATTI4 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00637 KDDKFICVVEYGGDVGPTFCNPKFFPTLCRQNCRSFKGAKGGKCVKQPKHKHIKCFCDYCKDD 63 Defensin-like protein 197 (Trypsin inhibitor ATTI-6; Plant defensin) "O22869, F4IR70, Q6ZZS7, Q6ZZU1, Q8GWN0" Belongs to the DEFL family ATTI6 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity). Caution: Was initially thought (PubMed:15082560) to be a protease inhibitor." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00638 RTTTSGYGMLFDSVACEGGFEYCPRGGGNDKCTTFCRSLPNKYDFGVCDKIYACCCHINV 60 Defensin-like protein 199 (Plant defensin) Q2V4G5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00639 RETRMMEQTCPVFWPMVPCDANKCEQMCRDYYGSVPSYCNRIGTPIAECACSLTPC 56 Defensin-like protein 201 (Plant defensin) Q2V4N2 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00640 KTCKLFRGECPVDPCEPEKCDECCKATFGKQICGKCEQESTELHCHCRR 49 Putative defensin-like protein 202 (Plant defensin) Q2V3J6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00641 QTCFKGEAQEGVCVKVDGSKLCDLLCRATNTTWFGACEVEDNETHCHCYGPC 52 Putative defensin-like protein 203 (Plant defensin) Q2V424 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00642 HCDHFLGEAPVYPCKEKACKSVCKEHYHHACKGECEYHGREVHCHCYGDYH 51 Defensin-like protein 204 (Plant defensin) Q56XB0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00643 NCDTYLGEVTVYYPCRERDCEAQCYEHYPHSCKGECEHHDHVVHHDNEEEHCHCYGR 57 Defensin-like protein 205 (His-rich; Plant defensin) Q9M9M3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00644 ACFTFLGECGPEPFTGSNADCLACCVALYKSPPVCAGRVEGVPAHCHCYKS 51 Defensin-like protein 206 (Plant defensin) "Q94JR6, Q9M1Y2" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00645 ACFTFLGECGPEPFTGSNADCLACCVALYKSPPVCAGRVEGVPAHCHCYKS 51 Defensin-like protein 207 (Plant defensin) Q3E8R5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00646 ACFKFLGECGAVPFPGTNADCTSCCVGNFGSAVCAGRVEVEGGVKHCHCYGTS 53 Defensin-like protein 208 (Plant defensin) Q2V2Q8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00647 IITKTMNSKETIYLDNPAVSPSIDQNLVDIHLGHSFVQGVMSFCYDCGKACFRRGKNLARCQKFVCRCTISKLR 74 Defensin-like protein 209 (Plant defensin) Q2V3K2 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00648 IITKTMNSKETTYLDSPAVSPSIDQYLVDIHLGHSFLQGVMSFCYDCGKACFRRGKNLARCKKFVCRCTKSGIK 74 Defensin-like protein 210 (Plant defensin) Q2V3K4 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00649 IVMKSSNSKERTYPVTPALNPLTGQHSLRQRQLIFCDECANACFRRKKPVRSCQRFICRCAIRDVGY 67 Putative defensin-like protein 211 (Plant defensin) Q2V3K7 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00650 VLINGSSDEERTYSFSPRASPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRYSISDIK 71 Defensin-like protein 212 (Plant defensin) A8MRC6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains two disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00651 TLINGSSDEERTYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISDIK 71 Defensin-like protein 213 (Plant defensin) "Q4VP08, Q9LSW1" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00652 ILINESSDEERTYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISGIK 71 Defensin-like protein 214 (Plant defensin) Q4VP10 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00653 ILINESSDEQRIYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISGIK 71 Defensin-like protein 215 (Plant defensin) Q4VP07 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00654 ILINESSDEQRIYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISDIK 71 Defensin-like protein 216 (Plant defensin) P0CAY6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00655 ILIKESSEEERIYPFNPVASPFDPRSLNQILKIGKIGYCFDCARACMRRDRYIRTCSFERKLCRCSYSHIHHTHG 75 Defensin-like protein 217 (Plant defensin) Q4VP09 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00656 KNKKVVIIPGPKGERPDIKVVEGPSTVEDDFCYDCVRRCMVKGVGFYFRSCKGFVCRCYYPFMGGYGP 68 Defensin-like protein 218 (Plant defensin) Q2V370 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00657 FFKKLFLRASNIMIKSISEGKSQFSGPALSPNIDPADEHIGHSPEDMKIIFCQQCAFHCIEKKKNIAHCENSICRCTLEDIL 82 Defensin-like protein 219 (Plant defensin) Q2V305 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00658 NIMTKSISQVKSQFFSPALSPNVDPADEHIGHSPDDMKIIFCQQCAFHCIEKKKNIGNCENSICRCTLEDIL 72 Defensin-like protein 220 (Plant defensin) Q2V304 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00659 NIMTKSILEGKTQFSIPSLSSTIDPAYEHIGHFPDDMKIIFCQQCAFHCIEKKKNIPHCENSICRCTLENIL 72 Putative defensin-like protein 221 (Plant defensin) Q2V306 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00660 TVKSYSEEKTHSFDLTANPPIDLNIVDELPRDEHLGVSHADNVIGFCQECAHHCLQRKRVLGECRWFTCHCSRITIGVGL 80 Defensin-like protein 222 (Plant defensin) Q2V300 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00661 VVPSSFKRVEGPVTAASADFCYKCSRGCYRRYRRPVFCQGSICRCSSFIDDGY 53 Defensin-like protein 223 (Plant defensin) Q2V369 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00662 MKKFGCNTTHPFPGKCGNNGKSSWVSDMKKLPSAPKNRDIRCECSDRPSLARGMPGERVCRCDYDC 66 Putative defensin-like protein 225 (Protein SCRL1; SCR-like protein 1; Plant defensin) P82620 Belongs to the DEFL family SCRL1 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00663 KTKWGCDMNRPFPGKCGTNGKDTCISDIKKMPGAPKDLVVRCECSQRFVWKGYPPERLCKCQYDC 65 Defensin-like protein 226 (Protein SCRL2; SCR-like protein 2; Plant defensin) P82621 Belongs to the DEFL family SCRL2 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00664 IHVEQAGVCEFTGEFPGKCGNNGRKMCVEAMNKKNKGSPGENKKNLRCECFDNPVVILGRPKRICRCRNNC 71 Putative defensin-like protein 227 (Protein SCRL28; SCR-like protein 28; Plant defensin) P82647 Belongs to the DEFL family SCRL28 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00665 ANKRCHLNQMFTGKCGNDGNKACLGDFKNKRFRYDLCQCTDATQISPSLPPQRVCNCSRPC 61 Putative defensin-like protein 228 (Protein SCRL3; SCR-like protein 3; Plant defensin) P82622 Belongs to the DEFL family SCRL3 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00666 HVREVKSVETKAKRVKKVCEKAQVFEQNCGWDGNKTCIRGFNKIKEYPFHCECGIYDAPNSRRICKCKFPYSPC 74 Defensin-like protein 229 (Protein SCRL27; SCR-like protein 27; Plant defensin) P82646 Belongs to the DEFL family SCRL27 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity). Tissue specificity: Flower buds. " No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00667 EKLCTTIGDLDGKCSQDGEKLCMRYMTDQSKKKFLSCTCNNVVMLHKYKHYCECQSHCTPKQT 63 Putative defensin-like protein 230 (Protein SCRL24; SCR-like protein 24; Plant defensin) P82643 Belongs to the DEFL family SCRL24 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00668 KELCNRIEDIDGNCDFEGEKGCLKFMTNKYKKERHVSCTCTNLYMLHKTKRFCDCKHRCSG 61 Putative defensin-like protein 231 (Protein SCRL25; SCR-like protein 25; Plant defensin) P82644 Belongs to the DEFL family SCRL25 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00669 GAPPVECWSEILFSGKCGFHGKKKCYKEMESKLKQRVLKCRCEDVKKDSNTSKDEHYCGCQRENPYECN 69 Defensin-like protein 232 (Protein SCRL23; SCR-like protein 23; Plant defensin) P82642 Belongs to the DEFL family SCRL23 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity). Tissue specificity: Flower buds." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00670 GAPPQDCWNLVTFPAKCGIHGKKKCFKEMESKYQQRFLQCTCKNLKPEPKSPKDEHDCTCQRANPYECNS 70 Putative defensin-like protein 233 (Protein SCRL22; SCR-like protein 22; Plant defensin) P82641 Belongs to the DEFL family SCRL22 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity). Tissue specificity: Expressed at least in stem, root, rosette leaves and flower buds." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00671 VLKPMDQCGRKDIFLGGCGSNGSKTCINDFVKKGGVAAKPSSCECDDFGEEHLCRCYVPC 60 Putative defensin-like protein 234 (Protein SCRL14; SCR-like protein 14; Plant defensin) P82633 Belongs to the DEFL family SCRL14 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00672 GLDPMAANLRVRKDIFIGGCGRDGNKTCMKDFVKKGGVMNKPISCECDNLGYEHLCRCNFS 61 Putative defensin-like protein 235 (Protein SCRL26; SCR-like protein 26; Plant defensin) P82645 Belongs to the DEFL family SCRL26 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: Defense response to fungus. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00673 QGKKKPPCPLGLSANGKCGHDGPKLCFSEMERKFNKDVVKTITHCKCWDDRRNNVDKHRCTCYLKHGFPCTNG 73 Putative defensin-like protein 236 (Protein SCRL20; SCR-like protein 20; Plant defensin) P82639 Belongs to the DEFL family SCRL20 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00674 QAKKKRCPIGLHTYGKCGTDRAKFCFSEIESKLSFSKQVLNTISSCRCDDDRQGNKDLYWCQCDRREGRPCPAN 74 Putative defensin-like protein 237 (Protein SCRL21; SCR-like protein 21; Plant defensin) "P82640, F4JMF8" Belongs to the DEFL family SCRL21 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00675 QVKPTGCQGGQRYRGKCGTNGTKTCVKDMMLPKLFKTKRCDCQDMLGTFKGWHFCTCYSGRPGC 64 Putative defensin-like protein 238 (Protein SCRL16; SCR-like protein 16; Plant defensin) P82635 Belongs to the DEFL family SCRL16 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00676 GLIRECDYTMEGYGPCGPNGRSLCLDTFWKTPPSPGLSKNLEGCRCEDRGKRPPIFTGLSHTCRCCWSYGGGSDD 75 Putative defensin-like protein 239 (Protein SCRL17; SCR-like protein 17; Plant defensin) P82636 Belongs to the DEFL family SCRL17 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00677 GLVRICNHRIEGYGTCGPNGRKICLDAFWKNQPSPGLSKNLEGCQCEDRRKRPQFKGLSHSCSCCWSYQGNSDE 74 Putative defensin-like protein 240 (Protein SCRL18; SCR-like protein 18; Plant defensin) P82637 Belongs to the DEFL family SCRL18 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00678 RTIRICDRKVEGNGTCGPNSNNICLDEFWKNPPSPRLAKSLEGCTCEPRGKRPKFKGLSHVCWCCWSYNSSNPAG 75 Defensin-like protein 241 (Protein SCRL19; SCR-like protein 19; Plant defensin) P82638 Belongs to the DEFL family SCRL19 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00679 HEEPKVAPTEELMFAPSNQPRYCRSRQVFDGSCTDRGTPRTTCFLDFLGARSASEMPKNCDCTPQPNNKRLCECSVICTDCCVKN 85 Defensin-like protein 242 (Protein SCRL10; SCR-like protein 10; Plant defensin) "P82629, Q6GKW3" Belongs to the DEFL family SCRL10 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00680 HLSHEEPMKEPEYCRWTNAFNGTCSDRGNPQTMCFFDFLDAHTARVMPKNCACNDLPGNKRYCECSFVCNS 71 Putative defensin-like protein 243 (Protein SCRL9; SCR-like protein 9; Plant defensin) P82628 Belongs to the DEFL family SCRL9 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00681 KELKWCPSKDVFNGSCTDTGSPSYTCFLDLLGSKSASAMPKNCKCTPLPHNRRQCDCFVVCDSN 64 Putative defensin-like protein 244 (Protein SCRL11; SCR-like protein 11; Plant defensin) P82630 Belongs to the DEFL family SCRL11 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00682 EESSMNIDAQRRPWCPSKKQVFGGSCGNDGAQQCLNNLLSTWDPSVRLSPVSCNCTPQPNNNILCSCPNMICP 73 Defensin-like protein 245 (Protein SCRL4; SCR-like protein 4; Plant defensin) "P82623, A0MJS7, A7RED2" Belongs to the DEFL family SCRL4 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity). Tissue specificity: Flower buds and roots." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00683 EESRMNINAERRPWCPSKIQMFDTNCEVDGAKQCLDLLISTWDPSVRLTRVSCICSDFPYRNMMCSCPNMICP 73 Defensin-like protein 246 (Protein SCRL5; SCR-like protein 5; Plant defensin) "P82624, Q1PFI3, Q5XVH8" Belongs to the DEFL family SCRL5 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity). Tissue specificity: Flower buds and stems." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00684 EKLSMDPTRRPWCPSKKQMFGGNCGNDGDSLCLMLLAASWDESLRHSSISCNCTTYPNYKILCSCPNMICP 71 Defensin-like protein 247 (Protein SCRL6; SCR-like protein 6; Plant defensin) "P82625, Q570C5, Q8L952" Belongs to the DEFL family SCRL6 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00685 EAAGERRQWCPSKQQVFRGSCSDDGGQKCLNDLLWTWNPSVRLSPIYCDCTPKRHNKRLCDCPSMICL 68 Defensin-like protein 249 (Protein SCRL7; SCR-like protein 7; Plant defensin) "P82626, A7RED3" Belongs to the DEFL family SCRL7 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00686 EKRPWCPTRKQIFDGSCNRTDYTQCFNDLRNTWDDIGDLCPTDCTCTPQPQNKRLCYCRYLPCPST 66 Defensin-like protein 250 (Protein SCRL8; CR-like protein 8; Plant defensin) P82627 Belongs to the DEFL family SCRL8 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00687 QRLVPLCKTIGYENPGKCPADGNKFCRRKLDDRYVKYKRCDCQDTKGRKQNHHRCICYMKLPCNQ 65 Putative defensin-like protein 251 (Protein SCRL12; SCR-like protein 12; Plant defensin) P82631 Belongs to the DEFL family SCRL12 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00688 QRRKPVCKLTGVLNPGKCPTAIHDASNLCSRKLASPNMTFKRCDCQNTEWRGKDHYQCTCYIKLPCNQ 68 Putative defensin-like protein 252 (Protein SCRL13; SCR-like protein 13; Plant defensin) P82632 Belongs to the DEFL family SCRL13 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00689 EVEPVPYCKVITWYDVKCGADGNKTCVDHLIKGHIYDVPVCDCSELTTSGILCTCQHRFPCKEPPPLHRISIRKQIRG 78 Putative defensin-like protein 253 (Protein SCRL15; SCR-like protein 15; Plant defensin) P82634 Belongs to the DEFL family SCRL15 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00690 VRHNLAVGDVCATNEECRINCQCDAAYCDLSCNMCVYMLHVMDTIDANIPNQPCISEYQNCGKKTSSLQ 69 Putative defensin-like protein 254 (Plant defensin) Q2V318 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains two disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00691 YEDSCSTDEECRRNCLCDVAYCDKSRDKCDYGFMNRVDVRFPKHPYISKNKDGSGR 56 Defensin-like protein 255 (Plant defensin) Q2V3Q8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains two disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks 2 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00692 VADYCNRDADCKRVCLRPYACNLTRHLCMCHPNDVSSSKQHCIPEHKGFGEGGPPPQRLKLYR 63 Putative defensin-like protein 256 (Plant defensin) Q2V483 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00693 RELAGVNEIFEIAARSSNNAGTARALQQAPPCKRDVDCSFECPKGGFCNDRLGTCDCF 58 Putative defensin-like protein 257 (Plant defensin) Q2V3S8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00694 RELTGAGKKLEVATRSSNYAGTARTLLQARPCQRDVDCNFQCPRIQGGQCNNHHGTCDCF 60 Putative defensin-like protein 258 (Plant defensin) Q2V3S7 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00695 RKLTGVADVIVEGEAASPQYGIIDENDTLNKSPSCKRDIDCTFQCRRGGFCNLILQKCECL 61 Defensin-like protein 259 (Plant defensin) "Q9LV55, A0MEY0" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00696 IQNSETSVNQNSCMPNEPRCTGCPGGGSGGYRGPPPPCCKNDSDCKAHCPEGGYCSNQCDCVCNLVKVMNNDVRCQVDTDCNMKCSKQGYCKLAS 95 Defensin-like protein 260 (Plant defensin) Q9LMX3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00697 REMVKAEVNCIGGKCPEGKKNCNCMPPIAHVMDDIRPCNTDGDCYKFCPRECELGTCYCRCDYGCTCTC 69 Putative defensin-like protein 262 (Plant defensin) Q2V4E0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00698 REMAKEEVNCIGGHCPDGKKDCNCLPLIAPTMDIYETNESCRTDNECIKYCPKGCKIVDCNFGTCLCEYC 70 Putative defensin-like protein 263 (Plant defensin) Q2V4D9 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00699 LEGESKVSGQVRDETPHTWYCKYDDNCRENCPGCTITKCNYGVCICSNCYHQQSDLGVESHM 62 Putative defensin-like protein 264 (Plant defensin) Q2V2W3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00700 SKGEEKTSGELRDVTPQRGGPCSYDNLCHNHCPGCKITQCVNGECVCLICYTPPL 55 Putative defensin-like protein 265 (Plant defensin) Q2V2W2 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00701 SEQRTRVSEVVREAEIHDGGQCTDDDICNKNCLDCIARQCIFQQCVCSKRFFPPNSQPNLRVKKH 65 Defensin-like protein 267 (Plant defensin) Q2V354 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00702 IPRGWQEPCFCPSKNPYCDCGDDLQVPTTSVISPKPIIEQCARCERNSQCNKVCPATCKYKVCIFNRTCEFSTCHCYRC 79 Defensin-like protein 268 (Plant defensin) "Q2V4N6, A0MJU3" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00703 RMSGDVTIQRGGSCNNDNTCHDTCPGCRITQCIFRQCVCTRCNTPRSSLRIESHM 55 Defensin-like protein 266 (Plant defensin) Q2V4F0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00704 RQMQRPQNVECVGGECQPKHPQQYFGSCFRDSDCRNSCFPYCRYQKCHHHECICSLCSSEVAPSPK 66 Defensin-like protein 269 (Plant defensin) Q2V4F4 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00705 TRIMDDSSDCVFKGPCQRRSDCYERCGLKPPSRAALCQPMGLQGRVCCCL 50 Putative defensin-like protein 270 (Plant defensin) Q2V2Z3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00706 TRIMDASSDCEFKGPCHKKEDCYDSCGVNKPPFNNAICVPGRDSFQCCCILS 52 Putative defensin-like protein 271 (Plant defensin) Q2V352 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00707 TREILSAEICGWNDPAVHCKTKEDCFEKCGGRPAKKVFCVRPGDHSYDRLCCCRA 55 Defensin-like protein 272 (Plant defensin) Q2V2W8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00708 NSVEKDVMDGPCRLRGTCNNDGDCDKHCHRSTDAAAMDGHCLFDKPTGPVCCCLFD 56 Putative defensin-like protein 274 (Plant defensin) Q2V2W7 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00709 KIVKRMQVGPSECVYRGRCRDSYECRSRCGPPEFSHETLGLCMFDYDDYEYFCCCTTNY 59 Defensin-like protein 275 (Plant defensin) Q2V4I9 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00710 SGCNFKGSCRTDDQCKRICRGHGLDPSFQLCVPYSSKGGKCCCLHYEGAPLSSEVI 56 Defensin-like protein 276 (Plant defensin) Q2V328 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00711 IVCNFEGHCVTSDDCINVCKSGEDPFLCVRSGPHKGMCCCLKTNGSVLE 49 Putative defensin-like protein 277 (Plant defensin) Q2V329 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00712 ARIQESTNDILKPITCNTNADCAKFCKGPIHNCVYHTCQCVPGNPHCC 48 Defensin-like protein 278 (Plant defensin) Q2V4F7 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00713 QESKKGILLKPKTCNTNADCAKFCKGPIQNCLYHTCACVPGNPHCC 46 Putative defensin-like protein 279 (Plant defensin) Q2V4F6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00714 DYKFHVCDPSFDEKDCDFECKEFGHPGGYCRPDRVQPRIRMCYCTDR 47 Putative defensin-like protein 280 (Plant defensin) Q2V4C4 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00715 TDPVPTPPGLHIPCGKGFTSKECNKYCTGVGYRRGYCAPDEEYPQISSCYCKWRI 55 Defensin-like protein 281 (Plant defensin) Q2V4C3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00716 NRQCVQAMDCTNVCSHGGLCTKNGKCVCWSPNVVINSGPPCWSDEMCFSTCGGNGGYCNYDIGGCFCQ 68 Putative defensin-like protein 282 (Plant defensin) Q2V2Y0 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00717 TAARENLHHQCFCESPSKCDCFPTTPTPPTSVNKSRKGGPLCTTDGDCKHFCRPKKGVCNIDFETCICQ 69 Putative defensin-like protein 283 (Plant defensin) Q2L6T1 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00718 KEDKECNDSKCLPNPSRINLEEGNIKRIDVNHGGICDTYLECGGLACSDYRRACCVNGKCVCRKQGQTLPDCPN 74 Defensin-like protein 285 (Plant defensin) "Q2V315, F4KBR3" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00719 LDEPNMDTISKSREYKCKIDLDCSNHIACRHCSYRNCKCDHGTCKCMP 48 Defensin-like protein 286 (Plant defensin) Q2L6T6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00720 AEEMGKGEVTISLRCKTKTECLKNIACEACVDCRCDKGICKCHGFTAETNNPTV 54 Defensin-like protein 287 (Plant defensin) Q2V4N4 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00721 KPRGKRPQSNFHAKRIRTVLQTLLVMLCTDYRCDKGLCKCHGFGGEKENPTAAPLTA 57 Putative defensin-like protein 288 (Plant defensin) Q2V4N5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00722 DASCLTTKECVVRCSDEDAQCIHGECHCPHLKVDIEPTKAIRCKTDLDCPDPHQCPKYDYYACLNNGECTCISV 74 Defensin-like protein 289 (Plant defensin) Q2V4I2 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains six disulfide bonds (By similarity). Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00723 TSSTLKESLTAEIKPTKVDRCKTDRDCPQSHRCQKDFYYGCVVGECICRAV 51 Defensin-like protein 291 (Plant defensin) Q2V472 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00724 MLLETDASRNKPSSYIPLCGSDNSCGGLWCPRKGGKYSCISMTCDIQEDCPKLVRCKDSPGPYCMEGFCTC 71 Defensin-like protein 292 (Plant defensin; Uncertain) P0CAY8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks the signal peptide and 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00725 SRNKLSSYIPLCGSNTYCGGLWCPKKGGKYSCISMSCDIQEDCPKLVRCKNSPGPYCMEGFCTC 64 Defensin-like protein 293 (Plant defensin) Q2V4A3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00726 SKNKSRSDLPLCGFREHCDGLWCPGEGGKYSCINWSCNFIEDCEKRIRCEKTGPCCFDGLCDCTNF 66 Defensin-like protein 294 (Plant defensin) Q2V4A4 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00727 HNFLPCVITNDCEYHHCSSGTVLCVNRQCHCSRSSTHQTKLDNLKKMDYAKKCKWTKDCDPRMRFTCVSGSYMCFDGLCTCTN 83 Defensin-like protein 295 (Plant defensin) Q4VNZ6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains six disulfide bonds (By similarity). Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00728 ELVLPCKTTYDCVNLPCLGRPPLCINGQCKCTTTLTHQAKLDNLRTMNDAKTCKYTSDCDPRMRYSCVSGSYICLNGFCTCT 82 Defensin-like protein 296 (Plant defensin) Q4VNZ5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains six disulfide bonds (By similarity). Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00729 QLIVPCKTSEQCKSIRCSNGSAQCVNKQCQCPSLKQIYSVTDVSCKTVSDCVASHQCPTGLSACIEGKCICLP 73 Putative defensin-like protein 298 (Plant defensin) Q2V459 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains six disulfide bonds (By similarity). Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00730 QFRCKSVAECDSRGCRVGTHVICNEHHICTCAHGSPIGGQCDGVEDCDLSGCPPNSHVICDRIGGNFCTCVPN 73 Defensin-like protein 301 (Plant defensin) Q3E715 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains six disulfide bonds (By similarity). Caution: Contains 6 disulfide bonds instead of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00731 MLRFVLVYIPVSVVSHTLCISLFIICSTRHTCFSKRYTCLLNICFCFFISSRIRNYF 57 Defensin-like protein 302 (Plant defensin) Q2V3W5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks the signal peptide and 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00732 RCYTNDDCKDGQPCPVPLACLFGSCICPWKSQSKLPICQIICANLD 46 Putative defensin-like protein 303 (Plant defensin) Q2V311 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00733 VRLTENMCFKDDDCINQGEWCPVLRVCSYAECICPWGTRSKLPSCQIICAHLDKKSVNSYNPCGCNYK 68 Putative defensin-like protein 304 (Plant defensin) Q2V309 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00734 KTNFDCVNLKCPTPFVTPKCVSGGCECPLKELLTLLSDTNYGVAACIDYCKAKGENAYTCILNHCYCRKPSM 72 Putative defensin-like protein 305 (Plant defensin) Q2V493 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00735 QSCNNDSDCTNLKCATKNIKCEQNKCQCLDERYIRAISLNTRSPRCNVQSCIDHCKAIGEVIYVCFTYHCYCRKPPM 77 Defensin-like protein 306 (Plant defensin) Q2V3H6 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00736 RTGYVSCKTNSDCVKLKCPTPFGGPKCISGSCECPFKELMTLPNDTNYGVAACIDYCKAKGEIVYACILNHCYSYKPPM 79 Putative defensin-like protein 307 (Plant defensin) Q2V3H5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00737 MIMGVSYHENRCHDWVDCAIWCKQWVPQPKCINRVCDCKPKSLPTNDEIPKSASSSSKN 59 Defensin-like protein 308 (Plant defensin) Q4VP04 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00738 MIMGVHYHEYRCHDWVDCAIWCKQWVPQPKCINRVCDCKPKSLPTNEEVPQSAYSSNSNY 60 Putative defensin-like protein 309 (Plant defensin) Q2V310 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00739 DICQTDRDCVEIGIPRCKRTGKMPICYNGYCCCICSAKRLPASTTRKPPSPSTSKLV 57 Defensin-like protein 311 (Plant defensin) Q2V3X3 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00740 QSPLSQSSHEFTVVSPYLSCFGIEECLFYLYFKLYDLCVILLCTWFDLSE 50 Putative defensin-like protein 312 (Plant defensin) Q2V3K9 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Caution: Could be the product of a pseudogene. Lacks 3 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00741 HVCLMSFGSSYRVGVHITHEKVAACPRQNQRLYSCDSLRILYHYSCLTTRDLLYICDCSDFENIICLIRLLLNLDFVEVKLV 82 Defensin-like protein 316 (Plant defensin) Q2V4J8 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00742 FKIHEVPEPTGKWCGYSVPMKPCINDDRVKRCIAENTHGWLMATGMCTSIPSLKDCYCMHQCP 63 Putative defensin-like protein 317 (Plant defensin) Q2V3Y5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains four disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00743 DCKHPVGPYTDSCFTDCVSGKYGYNYESAFCSRDETGTCKICCCELINE 49 Defensin-like protein 313 (Plant defensin) "Q3E8K0, Q1PDQ0" Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "Function: May have antifungal activity. PTM: Contains three disulfide bonds (By similarity). Caution: Lacks 1 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 11437247##15955924 Plant Mol Biol. 2001 May;46(1):17-34.##Plant Physiol. 2005 Jun;138(2):600-610. "Vanoosthuyse V, Miege C, Dumas C, Cock JM.##Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.##Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00744 MYLSSRTGSRLLFLVKASFNTFEKVATISSTLIYFVSHKLVSSRSCSHNFRNICGYIRHNCRKCIRFCFCTFSIKISLPLVIARRIEY 88 Putative defensin-like protein 315 (Plant defensin) Q2V3R5 Belongs to the DEFL family Unknown Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown Unknown Unknown "PTM: Contains two disulfide bonds (By similarity). Caution: Could be the product of a pseudogene. Lacks the signal peptide and 2 of the 4 disulfide bonds, which are conserved features of the family." No MICs found on DRAMP database Unknown 15955924 Plant Physiol. 2005 Jun;138(2):600-610. "Silverstein KA, Graham MA, Paape TD, VandenBosch KA." Genome organization of more than 300 defensin-like genes in Arabidopsis. DRAMP00745 GTCKAECPTWEGICINKAPCVKCCKAQPEKFTDGHCSKILRRCLCTKPC 49 Floral defensin-like protein 2 (PhD2; Plant defensin) Q8H6Q0 Belongs to the DEFL family D2 Petunia hybrida (Petunia) Antifungal Bridge Unknown Unknown "Function: Plant defense peptide with antifungal activity against F. oxysporum and Botrytis cinerea. Tissue specificity: Petals. Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin (By similarity). Biophysicochemical properties: pH dependence (Stable under extremes of pH); Temperature dependence (Stable under extremes of temperature). PTM: Contains five disulfide bonds 3-49; 7-23; 14-36; 20-43; 24-45 (By similarity)." "Fungi: Fusarium oxysporum (86% inhibition at 10 ?g/ml), Botrytis cinerea (41% inhibition at 10 ?g/ml)." Unknown 12644678 Plant Physiol. 2003 Mar;131(3):1283-1293. "Lay FT, Brugliera F, Anderson MA." Isolation and properties of floral defensins from ornamental tobacco and petunia. DRAMP00746 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC 47 Flower-specific defensin (NaD1; Plant defensin) Q8GTM0 Belongs to the DEFL family D1 Nicotiana alata (Winged tobacco) (Persian tobacco) Antifungal Combine helix and strand structure NaD1 adopts the cysteine-stabilized 汐汕 (CS汐汕) motif formed by a triple-stranded antiparallel 汕-sheet and a single 汐-helix that is tethered to the sheet via three disulfide bonds. The fourth disulfide bond reinforces the N- and C-terminal regions of the molecule. "4AAZ, 4AB0 resolved by X-ray." "Function: NaD1 is a member of a family of cationic peptides that displays growth inhibitory activity against several filamentous fungi, including Fusarium oxysporum. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43. Tissue specificity: Most abundant in the epidermal cell layers of the petals and sepals, within the connective cells of the anthers, and the cortical cells of the style. Not detected in the tapetum, pollen mother cells, the transmitting tissue, the vascular bundles of the anther and style or in leaves. Expressed also in ovaries, but barley detectable in roots. Biophysicochemical properties: pH dependence (Stable under extremes of pH); Temperature dependence (Stable under extremes of temperature." "Fungi: Fusarium oxysporum f. sp. Vasinfectum (IC50=1 ?M), Thielaviopsis basicola (IC50=0.80 ?M), Verticillium dahliae (IC50=0.75 ?M), Leptosphaeria maculans (IC50=0.80 ?M), Aspergillus nidulans (IC50=0.80 ?M), Candida albicans (IC50>10 ?M), Pichia pastoris (IC50>10 ?M), Saccharomyces cerevisiae (IC50>10 ?M).##Gram-negative bacteria: Escherichia coli (IC50>10 ?M), Pseudomonas aeruginosa (IC50>10 ?M);##Gram-positive bacteria: Staphylococcus aureus (IC50>10 ?M), Bacillus cereus (IC50>10 ?M).##HeLa cells (IC50>10 ?M)." Unknown 12644678##12473460##22511788##18339623 Plant Physiol. 2003 Mar;131(3):1283-1293.##J Mol Biol. 2003 Jan 3;325(1):175-188.##J Biol Chem. 2012 Jun 8;287(24):19961-72.##J Biol Chem. 2008 May 23;283(21):14445-52. "Lay FT, Brugliera F, Anderson MA.##Lay FT, Schirra HJ, Scanlon MJ, Anderson MA, Craik DJ.##Lay FT, Mills GD, Poon IK, Cowieson NP, Kirby N, Baxter AA, van der Weerden NL, Dogovski C, Perugini MA, Anderson MA, Kvansakul M, Hulett MD.##van der Weerden NL, Lay FT, Anderson MA." "Isolation and properties of floral defensins from ornamental tobacco and petunia.##The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP.##Dimerization of plant defensin NaD1 enhances its antifungal activity.##The plant defensin, NaD1, enters the cytoplasm of Fusarium oxysporum hyphae." DRAMP00747 RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKLLRRCLCTKPCVFDEKMIKTGAETLVEEAKTLAAALLEEEIMDN 80 Defensin-like protein (Flower-specific gamma-thionin; Plant defensin) P32026 Belongs to the DEFL family FST Nicotiana tabacum (Common tobacco) Antifungal Combine helix and strand structure Unknown 1MR4 resolved by NMR. "Function: Involved in floral organogenesis. May play a protective role in flowers by protecting the reproductive organs from potential pathogen attack. Tissue specificity: Found in petals, stamen and pistils, but not in sepals. In particular, accumulation in a configuration surrounding the inner reproductive whorls. Developmental stage: Accumulates in developing flowers and its level drops as flowers mature. PTM: Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43." Fungi: Fusarium oxysporum and Botrytis cinerea. Unknown 1495489##12473460 Mol Gen Genet. 1992 Jul;234(1):89-96.##J Mol Biol. 2003 Jan 3;325(1):175-188. "Gu Q, Kawata EE, Morse MJ, Wu HM, Cheung AY.##Lay FT, Schirra HJ, Scanlon MJ, Anderson MA, Craik DJ." "A flower-specific cDNA encoding a novel thionin in tobacco.##The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP." DRAMP00748 QDKCKKVYENYPVSKCQLANQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY 54 Defensin-like protein(Brazzein; Plants) P56552 Belongs to the DEFL family Unknown Pentadiplandra brazzeana "Antibacterial, Antifungal" Combine helix and strand structure "The brazzein fold, which contains one alpha-helix and three strands of antiparallel beta-sheet." 1BRZ resolved by NMR.##4HE7 resolved by X-ray. "Function: Taste-modifying protein; sweet-tasting. It is 2000 sweeter than sucrose on a molar basis. Has a pH-specific antimicrobial activity against bacteria and fungi. PTM: Contains four disulfide bonds 4-52; 16-37; 22-47; 26-49." "Gram-positive bacteria: Bacillus subtilis, Staphylococcus aureus.##Gram-positive bacterium: Escherichia coli.##Yeast: Candida albicans." Unknown 15118082##9628478 Proc Natl Acad Sci U S A. 2004 May 11;101(19):7363-7368.##Nat Struct Biol. 1998 Jun;5(6):427-431. "Yount NY, Yeaman MR.##Caldwell JE, Abildgaard F, Dzakula Z, Ming D, Hellekant G, Markley JL." Multidimensional signatures in antimicrobial peptides.##Solution structure of the thermostable sweet-tasting protein brazzein. DRAMP00749 ELCEKASKTWSGNCGNTGHCDNQCKSWEGAAHGACHVRNGKHMCFCYFNC 50 Defensin-like protein 1 (Dm-AMP1; Plant defensin) P0C8Y4 Belongs to the DEFL family Unknown Dahlia merckii (Bedding dahlia) Antifungal Bridge Unknown Unknown "Function: Possesses antimicrobial activity sensitive to inorganic cations. Has no inhibitory effect on insect gut alpha-amylase. Induces potential changes in fungal membranes and increased K+ efflux and Ca2+ uptake. Interacts with sphingolipids and ergosterols found in fungal plasma membranes. Biotechnological use: DmAMP1 expression in heterologous plants such as rice or papaya may provide a broad-spectrum disease resistance. PTM: Problely contains four disulfide bonds 3-50;14-35;20-44;24-46." "Gram-positive bacterium: Bacillus subtilis (IC50=150 ?g/mL).##Medium A: Botrytis cinerea (IC50=12 ?g/ml), Cladosporium sphaerospermum (IC50=3 ?g/ml), Fusarium culmorum (IC50=5 ?g/ml), Leptosphaeria maculans (IC50=1.5 ?g/ml), Penicillium digitatum (IC50=2 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=1 ?g/ml), Verticilium albo-atrum (IC50=4 ?g/ml). NOTE: Medium B = 1/2 strength potato dextrose broth.##Medium B: Botrytis cinerea (IC50>100 ?g/ml), Cladosporium sphaerospermum (IC50=12 ?g/ml), Fusarium culmorum (IC50=8 ?g/ml), Leptosphaeria maculans (IC50=15 ?g/ml), Penicillium digitatum (IC50=70 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=4 ?g/ml), Verticilium albo-atrum (IC50>100 ?g/ml).##NOTE: Medium B = Medium A supplemented with 1 mM CaCl2 and 50 mM KCI." cell membrabce 13129623##7628617##8663029##17216480 FEMS Microbiol Lett. 2003 Sep 12;226(1):169-173.##FEBS Lett. 1995 Jul 17;368(2):257-262.##Plant Physiol. 2002 Apr;128(4):1346-1358.##J Biol Chem. 1996 Jun 21;271(25):15018-15025.##Planta. 2007 Jun;226(1):87-97. "Thevissen K, Fran?∫ois IE, Takemoto JY, Ferket KK, Meert EM, Cammue BP.##Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF.##Fran?∫ois IE, De Bolle MF, Dwyer G, Goderis IJ, Woutors PF, Verhaert PD, Proost P, Schaaper WM, Cammue BP, Broekaert WF.##Thevissen K, Ghazi A, De Samblanx GW, Brownlee C, Osborn RW, Broekaert WF.##Zhu YJ, Agbayani R, Moore PH." "DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckii), interacts with sphingolipids from Saccharomyces cerevisiae.##Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae.##Fungal membrane responses induced by plant defensins and thionins.##Ectopic expression of Dahlia merckii defensin DmAMP1 improves papaya resistance to Phytophthora palmivora by reducing pathogen vigor." DRAMP00750 EVCEKASKTWSGNCGNTGHC 20 Defensin-like protein 2 (Dm-AMP2; Plant defensin) No entry found Belongs to the DEFL family Unknown Dahlia merckii (Bedding dahlia) Antifungal Unknown Unknown Unknown No comments found on DRAMP database "Medium A: Botrytis cinerea (IC50=10 ?g/ml), Cladosporium sphaerospermum (IC50=3 ?g/ml), Fusarium culmorum (IC50=5 ?g/ml), Leptosphaeria maculans (IC50=1 ?g/ml), Penicillium digitatum (IC50=2 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=1 ?g/ml), Verticilium albo-atrum (IC50=2 ?g/ml). NOTE: Medium A = 1/2 strength potato dextrose broth.##Medium B: Botrytis cinerea (IC50>100 ?g/ml), Cladosporium sphaerospermum (IC50=12 ?g/ml), Fusarium culmorum (IC50=12 ?g/ml), Leptosphaeria maculans (IC50=20 ?g/ml), Penicillium digitatum (IC50=50 ?g/ml), Trichoderma viride (IC50>100 ?g/ml), Septoria tritiei (IC50=2 ?g/ml), Verticilium albo-atrum (IC50>100 ?g/ml).##NOTE: Medium B = Medium A supplemented with 1 mM CaCl2 and 50 mM KCI." cell membrabce 8422949##7628617 FEBS Lett. 1993 Feb 1;316(3):233-240.##FEBS Lett. 1995 Jul 17;368(2):257-262. "Terras FR, Torrekens S, Van Leuven F, Osborn RW, Vanderleyden J, Cammue BP, Broekaert WF.##Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB, Broekaert WF." "A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.##Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae." DRAMP00751 RMCKTPSAKFKGYCVSSTNCKNVCRTEGFPTGSCDFHITSRKCYCYKPCP 50 Defensin-2 (Plant defensin) A4L7R8 Belongs to the DEFL family Def2 Pinus sylvestris (Scots pine) Antifungal Unknown Unknown Unknown "Function: Plant defense peptide. Has antifungal activity. PTM: Contains three disulfide bonds (By similarity)." No MICs found on DRAMP database Unknown 19253756 Tsitol Genet. 2008 Nov-Dec;42(6):55-60. "Koval'ova VA, Hut RT." Molecular cloning and characterization of Scotch pine Defensin-2. DRAMP00752 RMCKTPSGKFKGYCVNNTNCKNVCRTEGFPTGSCDFHVAGRKCYCYKPCP 50 "PsDef1 (P. sylvestris defensin 1, p1; Plant defensin)" A4L7R7 Belongs to the DEFL family Def1 Pinus sylvestris (Scots pine) Antifungal Unknown Unknown Unknown "Function: Plant defense peptide. Has antifungal activity. PTM: Contains four disulfide bonds (By similarity)." "Fungi: Botrytis cinerea (IC50=0.4 ?g/ml), Fusarium oxysporum (IC50=2.9 ?g/ml), Fusarium solani (IC50=0.9 ?g/ml), Heterobasidion annosum (IC50=1.4 ?g/ml), Candida albicans and Trichoderma reesei." Unknown 19683554 Peptides. 2009 Dec;30(12):2136-2143. "Kovaleva V, Kiyamova R, Cramer R, Krynytskyy H, Gout I, Filonenko V, Gout R." Purification and molecular cloning of antimicrobial peptides from Scots pine seedlings. DRAMP00753 ATKVKAKQRGKEKVSSGRPGQHN 23 Elicitor peptide 1 (AtPep1; Plant defensin) "Q9LV87, Q8LCK9" Belongs to the brassicaceae elicitor peptide family PEP1 Arabidopsis thaliana (Mouse-ear cress) Antifungal Unknown "Sequential removal of N-terminal amino acids has little effect on activity. Activity is completely abolished when nine C-terminal amino acids remained. Removal of the C-terminal asparagine from AtPep1(9-23), resultes in a decrease in activity (12 max approximately 100 nM)." Unknown "Function: Elicitor of plant defense. Induces the production of plant defensin (PDF1.2) and of H2O2. Promotes resistance to the root fungal pathogen P. irregulare. Subunit structure: Interacts with its receptor PEPR1. Induction: By wounding, methyl jasmonate (MeJA), ethylene. The expression of the peptide PEP1 precursor is induced by the mature peptide PEP1." Pythium irregulare Unknown 16785434##16785433##18824048 Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10098-103.##Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10104-9.##Peptides. 2008 Dec;29(12):2083-9. "Huffaker A, Pearce G, Ryan CA.##The cell surface leucine-rich repeat receptor for AtPep1, an endogenous peptide elicitor in Arabidopsis, is functional in transgenic tobacco cells.##Pearce G, Yamaguchi Y, Munske G, Ryan CA." "An endogenous peptide signal in Arabidopsis activates components of the innate immune response.##The cell surface leucine-rich repeat receptor for AtPep1, an endogenous peptide elicitor in Arabidopsis, is functional in transgenic tobacco cells.##Structure-activity studies of AtPep1, a plant peptide signal involved in the innate immune response." DRAMP00754 DNKAKSKKRDKEKPSSGRPGQTNSVPNAAIQVYKED 36 Elicitor peptide 2 (AtPep2; Plant defensin) "Q9LV88, Q8L902" Belongs to the brassicaceae elicitor peptide family PEP2 Arabidopsis thaliana (Mouse-ear cress) Unkonw Unknown Unknown Unknown Function: Elicitor of plant defense (By similarity). No MICs found on DRAMP database Unknown 16785434##10718197 "Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10098-103.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." "Huffaker A, Pearce G, Ryan CA.##Sato S, Nakamura Y, Kaneko T, Katoh T, Asamizu E, Kotani H, Tabata S." "An endogenous peptide signal in Arabidopsis activates components of the innate immune response.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." DRAMP00755 EIKARGKNKTKPTPSSGKGGKHN 23 Elicitor peptide 3 (AtPep3; Plant defensin) Q8LAX3 Belongs to the brassicaceae elicitor peptide family PEP3 Arabidopsis thaliana (Mouse-ear cress) Unkonw Unknown Unknown Unknown Function: Elicitor of plant defense (By similarity). No MICs found on DRAMP database Unknown 16785434##10718197 "Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10098-103.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." "Huffaker A, Pearce G, Ryan CA.##Sato S, Nakamura Y, Kaneko T, Katoh T, Asamizu E, Kotani H, Tabata S." "An endogenous peptide signal in Arabidopsis activates components of the innate immune response.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." DRAMP00756 GLPGKKNVLKKSRESSGKPGGTNKKPF 27 Elicitor peptide 4 (AtPep4; Plant defensin) "Q9FIA9, Q8L9J1" Belongs to the brassicaceae elicitor peptide family PEP4 Arabidopsis thaliana (Mouse-ear cress) Unkonw Unknown Unknown Unknown Function: Elicitor of plant defense (By similarity). No MICs found on DRAMP database Unknown 16785434##10718197 "Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10098-103.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." "Huffaker A, Pearce G, Ryan CA.##Sato S, Nakamura Y, Kaneko T, Katoh T, Asamizu E, Kotani H, Tabata S." "An endogenous peptide signal in Arabidopsis activates components of the innate immune response.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." DRAMP00757 SLNVMRKGIRKQPVSSGKRGGVNDYDM 27 Elicitor peptide 5 (AtPep5; Plant defensin) "Q8LD63, Q9FIA8" Belongs to the brassicaceae elicitor peptide family PEP5 Arabidopsis thaliana (Mouse-ear cress) Unkonw Unknown Unknown Unknown Function: Elicitor of plant defense (By similarity). No MICs found on DRAMP database Unknown 16785434##10718197 "Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10098-103.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." "Huffaker A, Pearce G, Ryan CA.##Sato S, Nakamura Y, Kaneko T, Katoh T, Asamizu E, Kotani H, Tabata S." "An endogenous peptide signal in Arabidopsis activates components of the innate immune response.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." DRAMP00758 ITAVLRRRPRPPPYSSGRPGQNN 23 Elicitor peptide 6 (AtPep6; Plant defensin) Q9SIZ9 Belongs to the brassicaceae elicitor peptide family PEP6 Arabidopsis thaliana (Mouse-ear cress) Unkonw Unknown Unknown Unknown Function: Elicitor of plant defense (By similarity). No MICs found on DRAMP database Unknown 16785434##10718197 "Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10098-103.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." "Huffaker A, Pearce G, Ryan CA.##Sato S, Nakamura Y, Kaneko T, Katoh T, Asamizu E, Kotani H, Tabata S." "An endogenous peptide signal in Arabidopsis activates components of the innate immune response.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones." DRAMP00759 VSGNVAARKGKQQTSSGKGGGTN 23 Elicitor peptide 7 (AtPep7; Plant defensin) "P0C1T5, Q1G3G0" Belongs to the brassicaceae elicitor peptide family PEP7 Arabidopsis thaliana (Mouse-ear cress) Unkonw Unknown Unknown Unknown Function: Elicitor of plant defense (By similarity). No MICs found on DRAMP database Unknown 16785434##10718197##17147637 "Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10098-103.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones.##Plant Biotechnol J. 2006 May;4(3):317-324." "Huffaker A, Pearce G, Ryan CA.##Sato S, Nakamura Y, Kaneko T, Katoh T, Asamizu E, Kotani H, Tabata S.##Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P." "An endogenous peptide signal in Arabidopsis activates components of the innate immune response.##Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones.##Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations." DRAMP00760 RECKAQGRHGTCFRDANCVQVCEKQAGWSHGDCRAQFKCKCIFEC 45 NmDef02 (Plants) No entry found Belongs to the defensin family Unknown Nicotiana megalosiphon Antifungal Unknown Unknown Unknown "Transgenic plants: Constitutive expression of NmDef02 gene in transgenic tobacco and potato plants enhanced resistance against various plant microbial pathogens, including the oomycete Phytophthora infestans, causal agent of the economically important pot" No MICs found on DRAMP database Unknown 20626828 Plant Biotechnol J. 2010 Aug;8(6):678-690. "Portieles R, Ayra C, Gonzalez E, Gallo A, Rodriguez R, Chac??n O, L??pez Y, Rodriguez M, Castillo J, Pujol M, Enriquez G, Borroto C, Trujillo L, Thomma BP, Borr??s-Hidalgo O." "NmDef02, a novel antimicrobial gene isolated from Nicotiana megalosiphon confers high-level pathogen resistance under greenhouse and field conditions." DRAMP00761 AWKLFDDGV 9 Cr-ACP1 (C. revoluta anticancer peptide 1; Plant defensin) No entry found Unknown Unknown Cycas revoluta (cycad seeds) "Antibacterial, Anticancer" Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 21882228 J. Cell Biochem. 2012 Jan;113(1):184-193. "Mandal SM, Migliolo L, Das S, Mandal M, Franco OL, Hazra TK." Identification and characterization of a bactericidal and proapoptotic peptide from Cycas revoluta seeds with DNA binding properties. DRAMP00762 GLPVCGETCFGGTCNTPGCTCDPWPVCTRN 30 Vaby D (Plant defensin) No entry found Unknown Unknown Viola abyssinica (Ethiopian highlands) "Antibacterial, Antifungal, Antiviral, Anticancer" Bridge Unknown Unknown PTM: Contains three disulfide bonds No MICs found on DRAMP database Unknown 21434649 J Nat Prod. 2011 Apr 25;74(4):727-731. "Yeshak MY, Burman R, Asres K, G??ransson U." Cyclotides from an extreme habitat: characterization of cyclic peptides from Viola abyssinica of the Ethiopian highlands. DRAMP00763 GLPVCGETCAGGTCNTPGCSCSWPICTRN 29 Vaby A (Plant defensin) No entry found Unknown Unknown Viola abyssinica (Ethiopian highlands) "Antibacterial, Antifungal, Antiviral, Anticancer" Bridge Unknown Unknown PTM: Contains three disulfide bonds No MICs found on DRAMP database Unknown 21434649 J Nat Prod. 2011 Apr 25;74(4):727-731. "Yeshak MY, Burman R, Asres K, G??ransson U." Cyclotides from an extreme habitat: characterization of cyclic peptides from Viola abyssinica of the Ethiopian highlands. DRAMP00767 GDACGETCFTGICFTAGCSCNPWPTCTRN 29 ChaC1 (Chassatide C1; Plant defensin) No entry found Belongs to the cyclotide family Unknown Chassalia chartacea "Antibacterial, Anticancer" Unknown Unknown Unknown "IC50=9.8 ?M, HD50=51.9 ?M.##Note: IC50 (concentration that gives a survival index of 50%) and HD50 (concentration that causes 50% lysis of red blood cells)." "Gram-negative bacterium: Escherichia coli (MIC>80 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC>80 ?M), Staphylococcus epidermidis (MIC>80 ?M)." Unknown 22467870 J Biol Chem. 2012 May 18;287(21):17598-17607. "Nguyen GK, Lim WH, Nguyen PQ, Tam JP." Novel Cyclotides and Uncyclotides with Highly Shortened Precursors from Chassalia chartacea and Effects of Methionine Oxidation on Bioactivities. DRAMP00768 GIPCAESCVWIPPCTITALMGCSCKNNVCYNN 32 ChaC2 (Chassatide C2; Plant defensin) No entry found Belongs to the cyclotide family Unknown Chassalia chartacea "Antibacterial, Anticancer" Unknown Unknown Unknown "IC50=2.4 ?M, HD50>25 ?M.##Note: IC50 (concentration that gives a survival index of 50%) and HD50 (concentration that causes 50% lysis of red blood cells)." "Gram-negative bacterium: Escherichia coli (MIC>80 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC>80 ?M), Staphylococcus epidermidis (MIC>80 ?M)." Unknown 22467870 J Biol Chem. 2012 May 18;287(21):17598-17607. "Nguyen GK, Lim WH, Nguyen PQ, Tam JP." Novel Cyclotides and Uncyclotides with Highly Shortened Precursors from Chassalia chartacea and Effects of Methionine Oxidation on Bioactivities. DRAMP00769 GASCGETCFTGICFTAGCSCNPWPTCTRN 29 ChaC4 (Chassatide C4; Plant defensin) No entry found Belongs to the cyclotide family Unknown Chassalia chartacea "Antibacterial, Anticancer" Unknown Unknown Unknown "IC50=9.8 ?M, HD50=51.9 ?M.##Note: IC50 (concentration that gives a survival index of 50%) and HD50 (concentration that causes 50% lysis of red blood cells)." "Gram-negative bacterium: Escherichia coli (MIC>80 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC>80 ?M), Staphylococcus epidermidis (MIC>80 ?M)." Unknown 22467870 J Biol Chem. 2012 May 18;287(21):17598-17607. "Nguyen GK, Lim WH, Nguyen PQ, Tam JP." Novel Cyclotides and Uncyclotides with Highly Shortened Precursors from Chassalia chartacea and Effects of Methionine Oxidation on Bioactivities. DRAMP00770 GEYCGESCYLIPCFTPGCYCVSRQCVNKN 29 ChaC10 (Chassatide C10; Plant defensin) No entry found Belongs to the cyclotide family Unknown Chassalia chartacea "Antibacterial, Anticancer" Unknown Unknown Unknown "IC50=5.0 ?M, HD50>25 ?M.##Note: IC50 (concentration that gives a survival index of 50%) and HD50 (concentration that causes 50% lysis of red blood cells)." "Gram-negative bacterium: Escherichia coli (MIC>80 ?M);##Gram-positive bacteria: Staphylococcus aureus (MIC>80 ?M), Staphylococcus epidermidis (MIC>80 ?M)." Unknown 22467870 J Biol Chem. 2012 May 18;287(21):17598-17607. "Nguyen GK, Lim WH, Nguyen PQ, Tam JP." Novel Cyclotides and Uncyclotides with Highly Shortened Precursors from Chassalia chartacea and Effects of Methionine Oxidation on Bioactivities. DRAMP00771 GIACGESCVFLGCFIPGCSCKSKVCYFN 28 Psyle A (Cyclotides; Plants) No entry found Belongs to the cyclotide family Unknown Psychotria leptothyrsa Anticancer Unknown Unknown Unknown Function: Cyclotide cytotoxicity on the human lymphoma cell line U-937 GTB (IC50=26 ?M). No MICs found on DRAMP database Unknown 20575512 J Nat Prod. 2010 Jul 23;73(7):1207-1213. "Gerlach SL, Burman R, Bohlin L, Mondal D, G??ransson U." "Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsa." DRAMP00772 KLCGETCFKFKCYTPGCSCSYPFCK 25 Psyle C (uncyclotides; Plants) No entry found Unknown Unknown Psychotria leptothyrsa Anticancer Unknown Unknown Unknown Cyclotide cytotoxicity on the human lymphoma cell line U-937 GTB (IC50=3.5 ?M). No MICs found on DRAMP database Unknown 20575512 J Nat Prod. 2010 Jul 23;73(7):1207-1213. "Gerlach SL, Burman R, Bohlin L, Mondal D, G??ransson U." "Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsa." DRAMP00773 GVIPCGESCVFIPCISSVLGCSCKNKVCYRD 31 Psyle E (Cyclotides; Plants) No entry found Belongs to the cyclotide family Unknown Psychotria leptothyrsa Anticancer Unknown Unknown Unknown Function: Cyclotide cytotoxicity on the human lymphoma cell line U-937 GTB (IC50=0.76 ?M). No MICs found on DRAMP database Unknown 20575512 J Nat Prod. 2010 Jul 23;73(7):1207-1213. "Gerlach SL, Burman R, Bohlin L, Mondal D, G??ransson U." "Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsa." DRAMP00775 GIPCGESCVFIPCLTSAIDCSCKSKVCYRN 30 Mram 8 (Plants) No entry found Belongs to the cyclotide family Unknown Viola philippica Anticancer Unknown Unknown Unknown Function: The novel cyclotides show cytotoxic activity against several cancer cell lines. "Cancer cell lines: BGC-823 (IC50=1.75㊣0.05 ?M), MM96L (IC50=4.91㊣0.04 ?M), HeLa (IC50=15.5㊣0.06 ?M).##Non-cancer cell line: HFF-1 (IC50=3.19㊣0.01 ?M)." Unknown 21723349 Peptides. 2011 Aug;32(8):1719-1723. "He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N." Isolation and characterization of cytotoxic cyclotides from Viola philippica. DRAMP00776 GSIPCEGSCVFIPCISAIIGCSCSNKVCYKN 31 Viphi G (Plants) No entry found Belongs to the cyclotide family Unknown Viola philippica Anticancer Unknown Unknown Unknown Function: The novel cyclotides show cytotoxic activity against several cancer cell lines. Note: Activity tested together with Viphi F. "Cancer cell lines: BGC-823 (IC50=2.91㊣0.06 ?M), MM96L (IC50=1.03㊣0.03 ?M), HeLa (IC50=6.35㊣0.31 ?M).##Non-Cancer cell line: HFF-1 (IC50=1.76㊣0.12 ?M)." Unknown 21723349 Peptides. 2011 Aug;32(8):1719-1723. "He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N." Isolation and characterization of cytotoxic cyclotides from Viola philippica. DRAMP00777 GSIPCGESCVFIPCISAIIGCSCSSKVCYKN 31 Viphi F (Plants) No entry found Belongs to the cyclotide family Unknown Viola philippica Anticancer Unknown Unknown Unknown Function: The novel cyclotides show cytotoxic activity against several cancer cell lines. Note: Activity tested together with Viphi G. "Cancer cell lines: BGC-823 (IC50=2.91㊣0.06 ?M), MM96L (IC50=1.03㊣0.03 ?M), HeLa (IC50=6.35㊣0.31 ?M)##Non-Cancer cell line: HFF-1 (IC50=1.76㊣0.12 ?M)." Unknown 21723349 Peptides. 2011 Aug;32(8):1719-1723. "He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N." Isolation and characterization of cytotoxic cyclotides from Viola philippica. DRAMP00778 GSIPCGESCVFIPCISAVIGCSCSNKVCYKN 31 Viphi E (Plants) No entry found Belongs to the cyclotide family Unknown Viola philippica Anticancer Unknown Unknown Unknown Function: The novel cyclotides show cytotoxic activity against several cancer cell lines. Note: Activity tested together with Viphi D. "Cancer cell lines: MM96L (IC50=2.51㊣0.03 ?M), HeLa (IC50=5.24㊣0.40 ?M).##Non-Cancer cell line: HFF-1 (IC50=1.55㊣0.09 ?M)." Unknown 21723349 Peptides. 2011 Aug;32(8):1719-1723. "He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N." Isolation and characterization of cytotoxic cyclotides from Viola philippica. DRAMP00779 GIPCGESCVFIPCISSVIGCSCSSKVCYRN 30 Viphi D (Plants) No entry found Belongs to the cyclotide family Unknown Viola philippica Anticancer Unknown Unknown Unknown Function: The novel cyclotides show cytotoxic activity against several cancer cell lines. Note: Activity tested together with Viphi E. "Cancer cell lines: MM96L (IC50=2.51㊣0.03 ?M), HeLa (IC50=5.24㊣0.40 ?M).##Non-Cancer cell line: HFF-1 (IC50=1.55㊣0.09 ?M)." Unknown 21723349 Peptides. 2011 Aug;32(8):1719-1723. "He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N." Isolation and characterization of cytotoxic cyclotides from Viola philippica. DRAMP00780 GSIPCGESCVFIPCISSVIGCACKSKVCYKN 31 Viphi A (Plants) No entry found Belongs to the cyclotide family Unknown Viola philippica Anticancer Unknown Unknown Unknown Function: The novel cyclotides show cytotoxic activity against several cancer cell lines. "Cancer cell lines: BGC-823 (IC50=1.75㊣0.05 ?M), MM96L (IC50=4.91㊣0.04 ?M), HeLa (IC50=15.5㊣0.06 ?M).##Non-cancer cell line: HFF-1 (IC50=3.19㊣0.01 ?M)." Unknown 21723349 Peptides. 2011 Aug;32(8):1719-1723. "He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N." Isolation and characterization of cytotoxic cyclotides from Viola philippica. DRAMP00781 GLPVCGETCVGGTCNTPGCGCSWPVCTRN 29 Viba 17 (Plants) No entry found Belongs to the cyclotide family Unknown Viola philippica Anticancer Unknown Unknown Unknown Function: The novel cyclotides show cytotoxic activity against several cancer cell lines. Note: Activity tested together with Viba 15. "Cancer cell lines: BGC-823 (IC50=1.32㊣0.15 ?M), MM96L (IC50=3.10㊣0.06 ?M), HeLa (IC50=10.21㊣0.43 ?M).##Non-Cancer cell line: HFF-1 (IC50=2.38㊣0.09 ?M)." Unknown 21723349 Peptides. 2011 Aug;32(8):1719-1723. "He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N." Isolation and characterization of cytotoxic cyclotides from Viola philippica. DRAMP00782 GLPVCGETCVGGTCNTPGCACSWPVCTRN 29 Viba 15 (Plants) No entry found Belongs to the cyclotide family Unknown Viola philippica Anticancer Unknown Unknown Unknown Function: The novel cyclotides show cytotoxic activity against several cancer cell lines. Activity tested together with Viba 17. "Cancer cell lines: BGC-823 (IC50=1.32㊣0.15 ?M), MM96L (IC50=3.10㊣0.06 ?M), HeLa (IC50=10.21㊣0.43 ?M).##Non-Cancer cell line: HFF-1 (IC50=2.38㊣0.09 ?M)." Unknown 21723349 Peptides. 2011 Aug;32(8):1719-1723. "He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N." Isolation and characterization of cytotoxic cyclotides from Viola philippica. DRAMP00783 GIPCGESCVWIPCITSAIGCSCKSKVCYRN 30 Vitri peptide A (Plant defensin) P83840 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Anticancer Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has strong cytotoxic activity against human lymphoma U-937 GTB and human myeloma RPMI-8226/s cell lines. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27." "Cancer cell lines: U-937 GTB (lymphoma) (IC50=0.6 ?M), RPMI-8226/s (myeloma) (IC50=1 ?M)." Unknown 14987049 J Nat Prod. 2004 Feb;67(2):144-147. "Svang?rd E, G?ransson U, Hocaoglu Z, Gullbo J, Larsson R, Claeson P, Bohlin L." Cytotoxic cyclotides from Viola tricolor. DRAMP00784 GLPVCGETCVGGTCNTPGCSCSWPVCTRN 29 Varv peptide A (Varv A; Plant defensin) "Q5USN7, P58446" Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Anticancer Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has cytotoxic activity against a variety of drug-resistant and drug-sensitive human tumor cell lines, and against primary chronic lymphocytic leukemia cells. Has weak cytotoxic activity against primary ovarian carcinoma cells or normal lymphocytes. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26." "Human cancer cell lines: U-937 GTB (lymphoma) (IC50=6 ?M), RPMI-8226/s (myeloma) (IC50=3 ?M)." Unknown 21723349##14987049 Peptides. 2011 Aug;32(8):1719-1723.##J Nat Prod. 2004 Feb;67(2):144-147. "He W, Chan LY, Zeng G, Daly NL, Craik DJ, Tan N.##Svang??rd E, G??ransson U, Hocaoglu Z, Gullbo J, Larsson R, Claeson P, Bohlin L." Isolation and characterization of cytotoxic cyclotides from Viola philippica.##Cytotoxic cyclotides from Viola tricolor. DRAMP00785 GLPVCGETCFGGTCNTPGCSCDPWPMCSRN 30 Varv peptide B (Varv B; Plant defensin) P58447 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Anticancer Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 10075760 J Nat Prod. 1999 Feb;62(2):283-286. "G?ransson U, Luijendijk T, Johansson S, Bohlin L, Claeson P." Seven novel macrocyclic polypeptides from Viola arvensis. DRAMP00786 GVPICGETCVGGTCNTPGCSCSWPVCTRN 29 Varv peptide C (Varv C; Plant defensin) P58448 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Anticancer Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 10075760 J Nat Prod. 1999 Feb;62(2):283-286. "G?ransson U, Luijendijk T, Johansson S, Bohlin L, Claeson P." Seven novel macrocyclic polypeptides from Viola arvensis. DRAMP00787 GLPICGETCVGGSCNTPGCSCSWPVCTRN 29 Varv peptide D (Varv D; Plant defensin) P58449 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Anticancer Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 10075760 J Nat Prod. 1999 Feb;62(2):283-286. "G?ransson U, Luijendijk T, Johansson S, Bohlin L, Claeson P." Seven novel macrocyclic polypeptides from Viola arvensis. DRAMP00788 GLPICGETCVGGTCNTPGCSCSWPVCTRN 29 Varv peptide E (Varv E; Plant defensin) P83835 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Anticancer Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has cytotoxic activity against human lymphoma U-937 GTB and human myeloma RPMI-8226/s cell lines. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26." "Human cancer cell lines: U-937 GTB (lymphoma) (IC50=4 ?M), RPMI-8226/s (myeloma) (IC50=4 ?M)." Unknown 10075760##14987049 J Nat Prod. 1999 Feb;62(2):283-286.##J Nat Prod. 2004 Feb;67(2):144-147. "G?ransson U, Luijendijk T, Johansson S, Bohlin L, Claeson P.Svang??rd E, G??ransson U, Hocaoglu Z, Gullbo J, Larsson R, Claeson P, Bohlin L." Seven novel macrocyclic polypeptides from Viola arvensis.##Cytotoxic cyclotides from Viola tricolor. DRAMP00789 GVPICGETCTLGTCYTAGCSCSWPVCTRN 29 Varv peptide F (Varv F; Plant defensin) P58451 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Anticancer Combine helix and strand structure Unknown 2K7G resolved by NMR. "Function: Probably participates in a plant defense mechanism. Has cytotoxic activity against a variety of drug-resistant and drug-sensitive human tumor cell lines. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26." "Human tumor cell lines: RPMI-8226/s (IC50=5.90 ?M), RPMI-8226/Dox40 (IC50=3.14 ?M), RPMI-8226/LR-5 (IC50=6.31 ?M), U-937GTB (IC50=7.07 ?M), U-937Vcr (IC50=7.45 ?M), ACHN (IC50=2.63 ?M), CCRF-CEM (IC50=7.13 ?M), CCRF-CEM/VM-1 (IC50=7.15 ?M), NCI-H69 (IC50=7.49 ?M), NCI-H69AR (IC50=7.12 ?M)." Unknown 10075760##12477048##19211551 J Nat Prod. 1999 Feb;62(2):283-286.##Mol Cancer Ther. 2002 Apr;1(6):365-369.##J Biol Chem. 2009 Apr 17;284(16):10672-83. "G?ransson U, Luijendijk T, Johansson S, Bohlin L, Claeson P.##Lindholm P, G?ransson , Johansson S, Claeson P, Gullbo J, Larsson R, Bohlin L, Backlund A.##Wang CK, Hu SH, Martin JL, Sj?gren T, Hajdu J, Bohlin L, Claeson P, G?ransson U, Rosengren KJ, Tang J, Tan NH, Craik DJ." Seven novel macrocyclic polypeptides from Viola arvensis.##Cyclotides: a novel type of cytotoxic agents.##Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold. DRAMP00790 GVPVCGETCFGGTCNTPGCSCDPWPVCSRN 30 Varv peptide G (Varv G; Plant defensin) P58452 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Anticancer Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Contains three disulfide bonds 5-19; 9-21; 14-27." No MICs found on DRAMP database Unknown 10075760 J Nat Prod. 1999 Feb;62(2):283-286. "G?ransson U, Luijendijk T, Johansson S, Bohlin L, Claeson P." Seven novel macrocyclic polypeptides from Viola arvensis. DRAMP00791 GLPVCGETCFGGTCNTPGCSCETWPVCSRN 30 Varv peptide H (Varv H; Plant defensin) P58453 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Anticancer Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Contains three disulfide bonds 5-19; 9-21; 14-27." No MICs found on DRAMP database Unknown 10075760 J Nat Prod. 1999 Feb;62(2):283-286. "G?ransson U, Luijendijk T, Johansson S, Bohlin L, Claeson P." Seven novel macrocyclic polypeptides from Viola arvensis. DRAMP00792 GLPVCGETCTLGKCYTAGCSCSWPVCYRN 29 Vodo peptide N (Plant defensin) P83838 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Unkonw Unknown Forms a head-to-tail cyclic backbone and that six cysteine residues are involved in three disulphide bonds. 2AKS (model) "Function: Probably participates in a plant defense mechanism. PTM: Problely contains three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 12946412 Phytochemistry. 2003 Sep;64(1):135-142. "Svang??rd E, G?ransson , Smith D, Verma C, Backlund A, Bohlin L, Claeson P." Primary and 3-D modelled structures of two cyclotides from Viola odorata. DRAMP00793 GAPICGESCFTGKCYTVQCSCSWPVCTRN 29 Vodo peptide M (Plant defensin) P83839 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Unkonw Unknown Forms a head-to-tail cyclic backbone and that six cysteine residues are involved in three disulphide bonds. 1ZLO (model) "Function: Probably participates in a plant defense mechanism. PTM: Problely contains three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 12946412 Phytochemistry. 2003 Sep;64(1):135-142. "Svang??rd E, G?ransson , Smith D, Verma C, Backlund A, Bohlin L, Claeson P." Primary and 3-D modelled structures of two cyclotides from Viola odorata. DRAMP00794 GLPVCGETCVGGTCNTPGCSCSWPVCTRN 29 Cyclotide varv-A (Cyclic cyclotides; Plant defensin) P85525 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Unkonw Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Problely contains three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00796 GEFLKCGESCVQGECYTPGCSCDWPICKKN 30 Cliotide T2 (cT2; Plant defensin) No entry found Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) "Antibacterial, Anticancer" Unknown Unknown Unknown Function: Cliotide T2 shows stronger antimicrobial activity against the Gram-negative bacteria than the Gram-positive bacteria. Cliotide T2 was relatively nonhemolytic (HD50>100 ?M) and only lysed ??18% of the red blood cells at 40 ?M. "Gram-positive bacteria: Staphylococcus aureus ATCC12600, Enterococcus faecalis ATCC 47077 (less active);##Gram-negative bacteria: Escherichia coli ATCC 700926 (MIC>100 ?M), Pseudomonas aeruginosa ATCC 39018 (MIC>100 ?M), Klebsiella pneumonia ATCC 13883 (MIC>100 ?M)." Unknown 21596752 J Biol Chem. 2011 Jul 8;286(27):24275-24287. "Nguyen GK, Zhang S, Nguyen NT, Nguyen PQ, Chiu MS, Hardjojo A, Tam JP." Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family. DRAMP00797 GLPTCGETCTLGTCYVPDCSCSWPICMKN 29 Cliotide T3 (cT3; Plant defensin) No entry found Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) "Antibacterial, Anticancer" Unknown Unknown Unknown "Function: Cliotide T3 shows stronger antimicrobial activity against the Gram-negative bacteria than the Gram-positive bacteria. It also has hemolytic activity against human type A erythrocytes (HD50=13.1 ?M) and cytotoxicity against HeLa Cells (IC50=2.0 ?M). [Note: HD50 refers to the peptide concentration that causes 50% lysis of red blood cells; IC50 refers to the peptide concentration that causes 50% death of HeLa cells]. " "Gram-positive bacteria: Staphylococcus aureus ATCC12600, Enterococcus faecalis ATCC 47077 (less active);##Gram-negative bacteria: Escherichia coli ATCC 700926 (MIC>100 ?M), Pseudomonas aeruginosa ATCC 39018 (MIC>100 ?M), Klebsiella pneumonia ATCC 13883 (MIC>100 ?M)." Unknown 21596752 J Biol Chem. 2011 Jul 8;286(27):24275-24287. "Nguyen GK, Zhang S, Nguyen NT, Nguyen PQ, Chiu MS, Hardjojo A, Tam JP." Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family. DRAMP00799 GVIPCGESCVFIPCISAAIGCSCKNKVCYRN 31 Cycloviolin-A (Plant defensin) P84637 Belongs to the cyclotide family Unknown Leonia cymosa (Sacha uba) Antiviral Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has anti-HIV activity. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-21;9-23;14-28." Virus: HIV-1 (EC50=130 nM). Unknown 10813905 J Org Chem. 2000 Jan 14;65(1):124-128. "Hallock YF, Sowder RC 2nd, Pannell LK, Hughes CB, Johnson DG, Gulakowski R, Cardellina JH 2nd, Boyd MR." "Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa." DRAMP00800 GTACGESCYVLPCFTVGCTCTSSQCFKN 28 Cycloviolin-B (Plant defensin) P84638 Belongs to the cyclotide family Unknown Leonia cymosa (Sacha uba) Antiviral Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has anti-HIV activity. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-18;8-20;13-25." Virus: HIV-1 (EC50=130 nM). Unknown 10813905 J Org Chem. 2000 Jan 14;65(1):124-128. "Hallock YF, Sowder RC 2nd, Pannell LK, Hughes CB, Johnson DG, Gulakowski R, Cardellina JH 2nd, Boyd MR." "Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa." DRAMP00801 GIPCGESCVFIPCLTTVAGCSCKNKVCYRN 30 Cycloviolin-C (Plant defensin) P84639 Belongs to the cyclotide family Unknown Leonia cymosa (Sacha uba) Antiviral Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has anti-HIV activity. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20;8-22;13-27." Virus: HIV-1 (EC50=130 nM). Unknown 10813905 J Org Chem. 2000 Jan 14;65(1):124-128. "Hallock YF, Sowder RC 2nd, Pannell LK, Hughes CB, Johnson DG, Gulakowski R, Cardellina JH 2nd, Boyd MR." "Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa." DRAMP00802 GFPCGESCVFIPCISAAIGCSCKNKVCYRN 30 Cycloviolin-D (Plant defensin) P84640 Belongs to the cyclotide family Unknown Leonia cymosa (Sacha uba) Antiviral Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has anti-HIV activity. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27." Virus: HIV-1 (EC50=130 nM). Unknown 10813905 J Org Chem. 2000 Jan 14;65(1):124-128. "Hallock YF, Sowder RC 2nd, Pannell LK, Hughes CB, Johnson DG, Gulakowski R, Cardellina JH 2nd, Boyd MR." "Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa." DRAMP00803 GDPTFCGETCRVIPVCTYSAALGCTCDDRSDGLCKRN 37 Palicourein (Cyclotides; Plants) P84645 Belongs to the cyclotide family Unknown Palicourea condensata (Cappel) Antiviral Combine helix and strand structure Palicourein has an atypical size and composition within one of the surface-exposed loops. 1R1F resolved by NMR. "Function: Probably participates in a plant defense mechanism. Inhibits the cytopathic effects of the human immunodeficiency virus. In vitro activity: Palicourein inhibits the cytopathic effects of HIV-1RF infection of CEM-SS cells with an EC50 value of 0.1 ?M and an IC50 value of 1.5 ?M. PTM: This is a cyclic peptide which may contain three disulfide bonds 6-24; 10-26; 16-34." Virus: HIV. Unknown 11430013##14725768 J Nat Prod. 2001 Feb;64(2):249-250.##Structure. 2004 Jan;12(1):85-94. "Bokesch HR, Pannell LK, Cochran PK, Sowder RC 2nd, McKee TC, Boyd MR.##Barry DG, Daly NL, Bokesch HR, Gustafson KR, Craik DJ." A novel anti-HIV macrocyclic peptide from Palicourea condensata.##Solution structure of the cyclotide palicourein: implications for the development of a pharmaceutical framework. DRAMP00804 GIPCAESCVYIPCTVTALLGCSCSNRVCYN 30 Cycloviolacin-O1 (Plant defensin) P82230 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Combine helix and strand structure Unknown 1NBJ resolved by NMR. "Function: Probably participates in a plant defense mechanism. It shows haemolytic activity. PTM: This is a cyclic peptide which contains three disulfide bonds 4-21; 8-23; 13-28." No MICs found on DRAMP database Unknown 16872274##10600388##12482868 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 1999 Dec 17;294(5):1327-1336.##J Biol Chem. 2003 Mar 7;278(10):8606-8616. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C.##Rosengren KJ, Daly NL, Plan MR, Waine C, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif.##Twists, knots, and rings in proteins. Structural definition of the cyclotide framework." DRAMP00805 GIPCGESCVWIPCISSAIGCSCKSKVCYRN 30 Cycloviolacin-O2 (Plant defensin) "P58434, P85526" Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) & Viola odorata (Sweet violet) Insecticidal Combine helix and strand structure Unknown "2KCG, 2KNM, 2KNN resolved by NMR." "Function: Probably participates in a plant defense mechanism. Has strong cytotoxic activity against a variety of drug-resistant and drug-sensitive human tumor cell lines, and against primary chronic lymphocytic leukemia and ovarian carcinoma cells. Has weaker cytotoxic activity against normal lymphocytes. Has hemolytic activity. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00806 GIPCGESCVWIPCLTSAIGCSCKSKVCYRN 30 Cycloviolacin-O3 (Plant defensin) P58435 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00807 GIPCGESCVWIPCISSAIGCSCKNKVCYRN 30 Cycloviolacin-O4 (Plant defensin) P58436 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00808 GTPCGESCVWIPCISSAVGCSCKNKVCYKN 30 Cycloviolacin-O5 (Plant defensin) P58437 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00809 GTLPCGESCVWIPCISAVGCSCKSKVCYKN 30 Cycloviolacin-O6 (Plant defensin) P58438 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 5-21; 9-23; 14-28." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00810 SIPCGESCVWIPCTITALAGCKCKSKVCYN 30 Cycloviolacin-O7 (Plant defensin) P58439 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-21; 8-23; 13-28." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00811 GTLPCESCVWIPCISSVVGCSCKSKVCYKN 30 Cycloviolacin-O8 (Cyclotide c1; Plant defensin) "P58440, Q5USN9" Belongs to the cyclotide family Voc1 Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 5-21; 9-23; 14-28." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00812 GIPCGESCVWIPCLTSAVGCSCKSKVCYRN 30 Cycloviolacin-O9 (Vbc5; Plant defensin) "P58441, B1NRR2" Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) & Viola biflora (Yellow wood violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 16872274##10600388##18191970 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 1999 Dec 17;294(5):1327-1336.##Phytochemistry. 2008 Feb;69(4):939-952. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C.##Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif.##The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00813 GIPCGESCVYIPCLTSAVGCSCKSKVCYRN 30 Cycloviolacin-O10 (Plant defensin) P58442 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00814 GTLPCGESCVWIPCISAVVGCSCKSKVCYKN 31 Cycloviolacin-O11 (Cyclotide c2; Plant defensin) "P58443, Q5USP0" Belongs to the cyclotide family Voc2 Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 5-21; 9-23; 14-28." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00815 GLPICGETCVGGTCNTPGCSCSWPVCTRN 29 Cycloviolacin-O12 (Plant defensin) P83836 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 5-21; 9-21; 14-26." No MICs found on DRAMP database Unknown 16872274##10600388 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ.##Craik DJ, Daly NL, Bond T, Waine C." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif." DRAMP00816 GIPCGESCVWIPCISAAIGCSCKSKVCYRN 30 Cycloviolacin-O13 (Cyclotide c3; Plant defensin) Q5USN8 Belongs to the cyclotide family Voc3 Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has hemolytic activity (~11% haemolysis). PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00817 GSIPACGESCFKGKCYTPGCSCSKYPLCAKN 31 Cycloviolacin-O14 (Plant defensin) P85177 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Combine helix and strand structure Cycloviolacin O14 is shown to contain the CCK motif. 2GJ0 resolved by NMR. "Function: Probably participates in a plant defense mechanism. Has hemolytic activity (~11% haemolysis). PTM: This is a cyclic peptide which may contain three disulfide bonds 6-20; 10-22; 15-27." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00818 GLVPCGETCFTGKCYTPGCSCSYPICKKN 29 Cycloviolacin-O15 (Plant defensin) P85178 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has hemolytic activity. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00819 GLPCGETTCFTGKCYTPGCSCSYPICKKIN 30 Cycloviolacin-O16 (Plant defensin) P85179 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-18; 8-20; 13-25." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00820 GIPCGESCVWIPGISAAIGCSCKNKVCYRN 30 Cycloviolacin-O17 (Plant defensin) P85180 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00821 GIPCGESCVYIIPCTVTALAQCKCKSKVCYN 31 Cycloviolacin-O18 (Plant defensin) P85181 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00822 GTLPCGESCVWIPCISSVVGCSCKSKVCYKD 31 Cycloviolacin-O19 (Plant defensin) P85182 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-21; 9-23; 14-28." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00823 GIPCGESCVWIPCLTSAIGCSCKSKVCYKD 30 Cycloviolacin-O20 (Plant defensin) P85183 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00824 GLPVCGETCVTGSCYTPGCTCSWPVCTRN 29 Cycloviolacin-O21 (Plant defensin) P85184 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00825 GLPICGETCVGGTCNTPGCTCSWPVCTRN 29 Cycloviolacin-O22 (Plant defensin) P85185 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00826 GLPTCGETCFGGTCNTPGCTCDSSWPICTHN 31 Cycloviolacin-O23 (Plant defensin) P85186 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00827 DIFCGETCAFIPCITHVPGTCSCKSKVCYFN 31 Cycloviolacin-O25 (Plant defensin) P85188 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00828 GLPTCGETCFGGTCNTPGCTCDPWPVCTHN 30 Cycloviolacin-O24 (Plant defensin) P85187 Belongs to the cyclotide family Unknown Viola odorata (Sweet violet) Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has hemolytic activity. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 16872274 Biochem J. 2006 Nov 15;400(1):1-12. "Ireland DC, Colgrave ML, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability." DRAMP00829 GIPCGESCVYIPCLTSAIGCSCKSKVCYRN 30 Cycloviolacin-H1 (Plant defensin) P58433 Belongs to the cyclotide family Unknown Viola hederacea (Australian violet) Antimicrobial Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 10600388 J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Craik DJ, Daly NL, Bond T, Waine C." Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. DRAMP00830 SAIACGESCVYIPCFIPGCSCRNRVCYLN 29 Cycloviolacin-H2 (Plant defensin) P85233 Belongs to the cyclotide family Unknown Viola hederacea (Australian violet) Antimicrobial Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-19; 9-21; 14-26." Virus: HIV. Unknown 10600388 J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Craik DJ, Daly NL, Bond T, Waine C." Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. DRAMP00831 GLPVCGETCFGGTCNTPGCICDPWPVCTRN 30 Cycloviolacin-H3 (Plant defensin) P85232 Belongs to the cyclotide family Unknown Viola hederacea (Australian violet) Antiviral Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." Virus: HIV. Unknown 10600388 J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Craik DJ, Daly NL, Bond T, Waine C." Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. DRAMP00832 GIPCAESCVWIPCTVTALLGCSCSNNVCYN 30 Cycloviolacin-H4 (Plant defensin) P85234 Belongs to the cyclotide family Unknown Viola hederacea (Australian violet) Antiviral Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 10600388 J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Craik DJ, Daly NL, Bond T, Waine C." Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. DRAMP00833 GGTIFDCGETCFLGTCYTPGCSCGNYGFCYGTN 33 Cycloviolacin-Y1 (Plants) No entry found Belongs to the cyclotide family Unknown Viola yedoensis (Chinese herb) Antiviral Bridge Unknown Unknown Function: Has anti-HIV activity. PTM: Contains three disulfide bonds. No MICs found on DRAMP database Unknown 18081258 J Nat Prod. 2008 Jan;71(1):47-52. "Wang CK, Colgrave ML, Gustafson KR, Ireland DC, Goransson U, Craik DJ." Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis. DRAMP00834 GGTIFDCGESCFLGTCYTAGCSCGNWGLCYGTN 33 Cycloviolacin-Y2 (Plants) No entry found Belongs to the cyclotide family Unknown Viola yedoensis (Chinese herb) Antiviral Bridge Unknown Unknown Function: Has anti-HIV activity. PTM: Contains three disulfide bonds. No MICs found on DRAMP database Unknown 18081258 J Nat Prod. 2008 Jan;71(1):47-52. "Wang CK, Colgrave ML, Gustafson KR, Ireland DC, Goransson U, Craik DJ." Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis. DRAMP00835 GGTIFDCGETCFLGTCYTAGCSCGNWGLCYGTN 33 Cycloviolacin-Y3 (Plants) No entry found Belongs to the cyclotide family Unknown Viola yedoensis (Chinese herb) Antiviral Bridge Unknown Unknown Function: Has anti-HIV activity. PTM: Contains three disulfide bonds. No MICs found on DRAMP database Unknown 18081258 J Nat Prod. 2008 Jan;71(1):47-52. "Wang CK, Colgrave ML, Gustafson KR, Ireland DC, Goransson U, Craik DJ." Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis. DRAMP00836 GVPCGESCVFIPCITGVIGCSCSSNVCYLN 30 Cycloviolacin-Y4 (Plants) No entry found Belongs to the cyclotide family Unknown Viola yedoensis (Chinese herb) Antiviral Bridge Unknown Unknown Function: Has anti-HIV activity. Cycloviolacins Y4 is more hemolytic than cycloviolacin Y1. PTM: Contains three disulfide bonds. No MICs found on DRAMP database Unknown 18081258 J Nat Prod. 2008 Jan;71(1):47-52. "Wang CK, Colgrave ML, Gustafson KR, Ireland DC, Goransson U, Craik DJ." Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis. DRAMP00837 GIPCAESCVWIPCTVTALVGCSCSDKVCYN 30 Cycloviolacin-Y5 (Plants) No entry found Belongs to the cyclotide family Unknown Viola yedoensis (Chinese herb) Antiviral Bridge Unknown Unknown "Function: Has anti-HIV activity. Cycloviolacin Y5 is the most hydrophobic of the cyclotides from V. yedoensis, and is more hemolytic than cycloviolacin Y1. PTM: Contains three disulfide bonds. " No MICs found on DRAMP database Unknown 18081258 J Nat Prod. 2008 Jan;71(1):47-52. "Wang CK, Colgrave ML, Gustafson KR, Ireland DC, Goransson U, Craik DJ." Anti-HIV cyclotides from the Chinese medicinal herb Viola yedoensis. DRAMP00838 GIGCGESCVWIPCVSAAIGCSCSNKICYRN 30 Cyclotide phyb-A (Plant defensin) B3EWH5 Belongs to the cyclotide family Unknown Petunia hybrida (Petunia) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism (By similarity). Tissue specificity: Expressed in midvein, lamina and periphery of leaves (at protein level). Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-2; 8-22; 13-27. " No MICs found on DRAMP database Unknown PubMed ID is not available J. Biol. Chem. 2012;287:27033-27046. "Poth A.G, Mylne J.S, Grassl J, Lyons R.E, Millar A.H, Colgrave M.L, Craik D.J." Cyclotides associate with leaf vasculature and are the products of a novel precursor in Petunia (Solanaceae). DRAMP00839 GVIPCGESCVFIPCISTVIGCSCKNKVCYRN 31 Cyclotide cter-A (Plant defensin) P86841 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-21; 9-23; 14-28. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00840 GVPCAESCVWIPCTVTALLGCSCKDKVCYLN 31 Cyclotide cter-B (Plant defensin) P86842 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00841 GVPCAESCVWIPCTVTALLGCSCKDKVCYLD 31 Cyclotide cter-C (Plant defensin) P86843 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00842 GIPCAESCVWIPCTVTALLGCSCKDKVCYLN 31 Cyclotide cter-D (Plant defensin) P86844 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00843 GIPCAESCVWIPCTVTALLGCSCKDKVCYLD 31 Cyclotide cter-E (Plant defensin) P86845 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00844 GIPCGESCVFIPCISSVVGCSCKSKVCYLD 30 Cyclotide cter-F (Plant defensin) P86846 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00845 GLPCGESCVFIPCITTVVGCSCKNKVCYNN 30 Cyclotide cter-G (Plant defensin) P86847 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00846 GLPCGESCVFIPCITTVVGCSCKNKVCYND 30 Cyclotide cter-H (Plant defensin) P86848 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00847 GTVPCGESCVFIPCITGIAGCSCKNKVCYIN 31 Cyclotide cter-I (Plant defensin) P86849 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-21; 9-23; 14-28. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00848 GTVPCGESCVFIPCITGIAGCSCKNKVCYID 31 Cyclotide cter-J (Plant defensin) P86850 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-21; 9-23; 14-28. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00849 HEPCGESCVFIPCITTVVGCSCKNKVCYN 29 Cyclotide cter-K (Plant defensin) P86851 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00850 HEPCGESCVFIPCITTVVGCSCKNKVCYD 29 Cyclotide cter-L (Plant defensin) P86852 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00851 GIPCGESCVFIPCITGIAGCSCKSKVCYRN 30 Cyclotide cter-O (Plant defensin) P86901 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27. " No MICs found on DRAMP database Unknown 21593408 Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10127-32. "Poth AG, Colgrave ML, Lyons RE, Daly NL, Craik DJ." Discovery of an unusual biosynthetic origin for circular proteins in legumes. DRAMP00852 GIPCGESCVFIPCITAAIGCSCKSKVCYRN 30 Cyclotide cter-P (Plant defensin) P86902 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00853 GIPCGESCVFIPCISTVIGCSCKNKVCYRN 30 Cyclotide cter-Q (Plant defensin) P86904 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00854 GIPCGESCVFIPCTVTALLGCSCKDKVCYKN 31 Cyclotide cter-R (Plant defensin) P86903 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00855 GSAFCGETCVLGTCYTPDCSCTALVCLKN 29 Cyclotide cter-N (Plant defensin) P86900 Belongs to the cyclotide family Unknown Clitoria ternatea (Butterfly pea) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 5-19; 9-21; 14-26. " No MICs found on DRAMP database Unknown 21194241 ACS Chem Biol. 2011 Apr 15;6(4):345-355. "Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ." "Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins." DRAMP00857 GLPVCGETCFGGTCNTPGCSCTWPICTRD 29 Kalata-B2 (Plant defensin) P58454 Belongs to the cyclotide family OAK4 Oldenlandia affinis Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Inhibitory effect on the growth and development of Helicoverpa armigera larvae suggests a role for the cyclotides in plant defense. Has hemolytic activity. PTM: Kalata-B2 is a cyclic peptide which contains three disulfide bonds 5-19; 9-21; 14-26." Insects: Helicoverpa armigera. Unknown 10600388##15654741##17534989 J Mol Biol. 1999 Dec 17;294(5):1327-1336.##Biochemistry. 2005 Jan 25;44(3):851-860.##Chembiochem. 2007 Jun 18;8(9):1001-1011. "Craik DJ, Daly NL, Bond T, Waine C.##Jennings CV, Rosengren KJ, Daly NL, Plan M, Stevens J, Scanlon MJ, Waine C, Norman DG, Anderson MA, Craik DJ.##Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif.##Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do M??bius strips exist in nature?##The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00858 GLPTCGETCFGGTCNTPGCTCDPWPICTRD 30 Kalata-B3 (Plant defensin) P58455 Belongs to the cyclotide family OAK2 Oldenlandia affinis Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has hemolytic activity. PTM: Kalata-B3 are cyclic peptides which may contain three disulfide bonds 5-19; 9-21; 14-27." No MICs found on DRAMP database Unknown 11535828 Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10614-9. "Jennings C, West J, Waine C, Craik D, Anderson M." Biosynthesis and insecticidal properties of plant cyclotides: the cyclic knotted proteins from Oldenlandia affinis. DRAMP00859 GLPVCGETCVGGTCNTPGCTCSWPVCTRD 29 Kalata-B4 (Plant defensin) P83938 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Beta strand (4 strands; 10 residues) "The charged residues (Glu3 and Arg24), along with the cation-binding site (near Glu3) are segregated on the other side of the molecule and in contact with polar head groups of detergent. The spatial structure of kalata B1 is only slightly changed during incorporation into micelles and represents a distorted triple-stranded beta-sheet cross-linked by a cystine knot. Detailed structural analysis and comparison with other knottins revealed structural conservation of the two-disulfide motif in cyclic and acyclic peptides." 1ZNU resolved by NMR. "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B4 is a cyclic peptide which may contain three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Binds to the micelle surface 10600388##16817894 J Mol Biol. 1999 Dec 17;294(5):1327-1336.##FEBS J. 2006 Jun;273(12):2658-2672. "Craik DJ, Daly NL, Bond T, Waine C.##Shenkarev ZO, Nadezhdin KD, Sobol VA, Sobol AG, Skjeldal L, Arseniev AS." Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif.##Conformation and mode of membrane interaction in cyclotides. Spatial structure of kalata B1 bound to a dodecylphosphocholine micelle. DRAMP00860 TPCGESCVYIPCISGVIGCSCTDKVCYLN 29 Kalata-B5 (Plant defensin) P58456 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Combine helix and strand structure "It displays a typical tightly folded cyclic Scystine knot structure. A range of pH and temperature titrations reveal that a conserved glutamic acid in loop 1 Sof the structure forms a key hydrogen bond network, similar to that reported previously for other cyclotides." 2KUX resolved by NMR. "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B5 is a cyclic peptide which contains three disulfide bonds 4-20; 8-22; 13-27." No MICs found on DRAMP database Unknown 10600388##17534989##20564013 J Mol Biol. 1999 Dec 17;294(5):1327-1336.##Chembiochem. 2007 Jun 18;8(9):1001-1011.##Biopolymers. 2010;94(5):647-658. "Craik DJ, Daly NL, Bond T, Waine C.##Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ.##Plan MR, Rosengren KJ, Sando L, Daly NL, Craik DJ." "Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif.##The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides.##Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis." DRAMP00861 GLPVCGETCFGGTCNTPGCSCSSWPICTRN 30 Kalata-B6 (Plant defensin) P58455 Belongs to the cyclotide family OAK2 Oldenlandia affinis Insecticidal Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has hemolytic activity. PTM: Kalata-B6 are cyclic peptides which may contain three disulfide bonds 5-19; 9-21; 14-27." No MICs found on DRAMP database cell membrabce 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00862 GLPVCGETCTLGTCYTQGCTCSWPICKRN 29 Kalata-B7 (Plant defensin) P58457 Belongs to the cyclotide family OAK3 Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has hemolytic activity. PTM: Kalata-B7 are cyclic peptides which may contain three disulfide bonds 5-19; 9-21; 14-27." No MICs found on DRAMP database cell membrabce 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00863 GSVLNCGETCLLGTCYTTGCTCNKYRVCTKD 31 Kalata-B8 (Plant defensin) P85175 Belongs to the cyclotide family Unknown Oldenlandia affinis Antiviral Beta strand (3 strands; 7 residues) Unknown 2B38 resolved by NMR. "Function: Probably participates in a plant defense mechanism. Inhibits the cytopathic effects of the human immunodeficiency virus. Has no hemolytic activity. PTM: Kalata-B8 is a cyclic peptide which contains three disulfide bonds 6-20; 10-22; 15-28." Virus: Human T-lymphoblast (CEM-SS) cells (EC50=2.5 ?M). Unknown 16207177##17534989 Biochem J. 2006 Feb 1;393(Pt 3):619-626.##Chembiochem. 2007 Jun 18;8(9):1001-1011. "Daly NL, Clark RJ, Plan MR, Craik DJ.##Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif.##The cyclotide fingerprint in Oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00864 GSVFNCGETCVLGTCYTPGCTCNTYRVCTKD 31 Kalata-B9 (Plant defensin) P85127 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B9 is a cyclic peptide which contains three disulfide bonds 6-20; 10-22; 15-28." No MICs found on DRAMP database Unknown 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00865 GSVFNCGETCVLGTCYTPGCTCNTYRVCTKD 31 Kalata-B9 (Linearized uncyclotides; Plant defensin) P85127 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B9 is a cyclic peptide which contains three disulfide bonds 6-20; 10-22; 15-28." No MICs found on DRAMP database Unknown 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00866 GLPTCGETCFGGTCNTPGCSCSSWPICTRD 30 Kalata-B10 (Plant defensin) P85128 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B10 are cyclic peptides which may contain three disulfide bonds 5-19; 9-21; 14-27." No MICs found on DRAMP database Unknown 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00867 GLPVCGETCFGGTCNTPGCSCTDPICTRD 29 Kalata-B11 (Plant defensin) P85129 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B11 are cyclic peptides which may contain three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00868 GSLCGDTCFVLGCNDSSCSCNYPICVKD 28 Kalata-B12 (Plant defensin) P85130 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Beta strand (3 strands; 11 residues) Unknown 2KVX resolved by NMR. "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B12 are cyclic peptides which may contain three disulfide bonds 4-18; 8-20; 13-25." No MICs found on DRAMP database Unknown 17534989##21466163 Chembiochem. 2007 Jun 18;8(9):1001-1011.##Biochemistry. 2011 May 17;50(19):4077-4086. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ.##Wang CK, Clark RJ, Harvey PJ, Rosengren KJ, Cemazar M, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides.##The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant." DRAMP00869 GLPVCGETCFGGTCNTPGCACDPWPVCTRD 30 Kalata-B13 (Plant defensin) P85131 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B13 are cyclic peptides which may contain three disulfide bonds 5-19; 9-21; 14-27." No MICs found on DRAMP database Unknown 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00870 GLPVCGESCFGGTCNTPGCACDPWPVCTRD 30 Kalata-B14 (Plant defensin) P85132 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B14 are cyclic peptides which may contain three disulfide bonds 5-19; 9-21; 14-27." No MICs found on DRAMP database Unknown 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00871 GLPVCGESCFGGSCYTPGCSCTWPICTRD 29 Kalata-B15 (Plant defensin) P85133 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B15 are cyclic peptides which may contain three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00872 GIPCAESCVYIPCTITALLGCKCQDKVCYD 30 Kalata-B16 (Plant defensin) P85134 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B16 are cyclic peptides which may contain three disulfide bonds 4-21; 8-23; 13-28." No MICs found on DRAMP database Unknown 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00873 GIPCAESCVYIPCTITALLGCKCKDQVCYN 30 Kalata-B17 (Plant defensin) P85135 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Kalata-B16 are cyclic peptides which may contain three disulfide bonds 4-21; 8-23; 13-28." No MICs found on DRAMP database Unknown 17534989 Chembiochem. 2007 Jun 18;8(9):1001-1011. "Plan MR, G??ransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ." "The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides." DRAMP00874 GLPVCGETCVGGTCNTPGCSCSWPVCTRN 29 Kalata-S (Plant defensin) P58458 Belongs to the cyclotide family Unknown Oldenlandia affinis Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Inhibits the cytopathic effects of the human immunodeficiency virus. Has no hemolytic activity. PTM: Kalata-S is a cyclic peptide which contains three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 10600388 J Mol Biol. 1999 Dec 17;294(5):1327-1336. "Craik DJ, Daly NL, Bond T, Waine C." Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. DRAMP00875 SISCGESCAMISFCFTEVIGCSCKNKVCYLN 31 Leaf cyclotide 1 (Vhl-1; Plant defensin) P84522 Belongs to the cyclotide family Unknown Viola hederacea (Australian violet) Antiviral Combine helix and strand structure "Vhl-1 adopts a compact and well defined structure including a distorted triple-stranded beta-sheet, a short 3(10) helical segment and several turns. It is stabilized by three disulfide bonds, which, together with backbone segments, form a cyclic cystine knot motif. The three-disulfide bonds are almost completely buried into the protein core, and the six cysteines contribute only 3.8% to the molecular surface." 1ZA8 resolved by NMR. "Function: Probably participates in a plant defense mechanism. Has anti-human immunodeficiency virus activity. Tissue specificity: Expressed in leaves. PTM: Vhl-1 is a cyclic peptide which contains three disulfide bonds 4-21; 8-23; 14-28." Virus: HIV (EC50=0.87 ?M). Unknown 15824119 J Biol Chem. 2005 Jun 10;280(23):22395-22405. "Chen B, Colgrave ML, Daly NL, Rosengren KJ, Gustafson KR, Craik DJ." "Isolation and characterization of novel cyclotides from Viola hederaceae: solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide." DRAMP00876 GLPVCGETCFTGTCYTNGCTCDPWPVCTRN 30 Leaf cyclotide 2 (Vhl-2; Plant defensin) P85231 Belongs to the cyclotide family Unknown Viola hederacea (Australian violet) Antiviral Beta strand (5 strands; 6 residues) "Analysis of surface hydrophobicity and haemolytic activity for a range of cyclotides indicates a correlation between them, with increasing hydrophobicity resulting in increased haemolytic activity." 2KUK resolved by NMR. "Function: Probably participates in a plant defense mechanism. Has hemolytic activity. Tissue specificity: Expressed in leaves. PTM: This is a cyclic peptide which contains three disulfide bonds 5-19; 9-21; 14-27." Virus: HIV. cell membrabce 15824119##PubMed ID is not available J Biol Chem. 2005 Jun 10;280(23):22395-22405.##Aust. J. Chem. 2010;63:771-778. "Chen B, Colgrave ML, Daly NL, Rosengren KJ, Gustafson KR, Craik DJ.##Daly NL, Chen B, Nguyencong P, Craik DJ." "Isolation and characterization of novel cyclotides from Viola hederaceae: solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide.##Structure and activity of the leaf-specific cyclotide vhl-2." DRAMP00879 GIPCGESCVFIPCITSVAGCSCKSKVCYRN 30 Circulin-C (CIRC; Plant defensin) P84641 Belongs to the cyclotide family Unknown Chassalia parviflora Antiviral Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Inhibits the cytopathic effects of the human immunodeficiency virus. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27." Virus: HIV-1 (EC50= 50-275 nM).##NOTE: EC50 = concentration that is 50% effective. Unknown 10691702 J Nat Prod. 2000 Feb;63(2):176-178. "Gustafson KR, Walton LK, Sowder RC Jr, Johnson DG, Pannell LK, Cardellina JH Jr, Boyd MR." New circulin macrocyclic polypeptides from Chassalia parvifolia. DRAMP00880 KIPCGESCVWIPCVTSIFNCKCKENKVCYHD 31 Circulin-D (CIRD; Plant defensin) P84642 Belongs to the cyclotide family Unknown Chassalia parviflora Antiviral Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Inhibits the cytopathic effects of the human immunodeficiency virus. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27." Virus: HIV-1 (EC50= 50-275 nM).##NOTE: EC50 = concentration that is 50% effective. Unknown 10691702 J Nat Prod. 2000 Feb;63(2):176-178. "Gustafson KR, Walton LK, Sowder RC Jr, Johnson DG, Pannell LK, Cardellina JH Jr, Boyd MR." New circulin macrocyclic polypeptides from Chassalia parvifolia. DRAMP00881 KIPCGESCVWIPCLTSVFNCKCENKVCYHD 30 Circulin-E (CIRE; Plant defensin) P84643 Belongs to the cyclotide family Unknown Chassalia parviflora Antiviral Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Inhibits the cytopathic effects of the human immunodeficiency virus. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27." Virus: HIV-1 (EC50= 50-275 nM).##NOTE: EC50 = concentration that is 50% effective. Unknown 10691702 J Nat Prod. 2000 Feb;63(2):176-178. "Gustafson KR, Walton LK, Sowder RC Jr, Johnson DG, Pannell LK, Cardellina JH Jr, Boyd MR." New circulin macrocyclic polypeptides from Chassalia parvifolia. DRAMP00882 KVCYRAIPCGESCVWIPCISAAIGCSCKN 29 Circulin-F (CIRF; Plant defensin) P84644 Belongs to the cyclotide family Unknown Chassalia parviflora Antiviral Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Inhibits the cytopathic effects of the human immunodeficiency virus. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-20; 8-22; 13-27." Virus: HIV-1 (EC50= 50-275 nM).##NOTE: EC50 = concentration that is 50% effective. Unknown 10691702 J Nat Prod. 2000 Feb;63(2):176-178. "Gustafson KR, Walton LK, Sowder RC Jr, Johnson DG, Pannell LK, Cardellina JH Jr, Boyd MR." New circulin macrocyclic polypeptides from Chassalia parvifolia. DRAMP00883 SCVYIPCTITALLGCSCKNKVCYNGIPCAE 30 Cyclotide hypa-A (hypa-A; Plant defensin) P58445 Belongs to the cyclotide family Unknown Hybanthus parviflorus (Violetilla) (Viola parvifloria) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown "Function: Probably participates in a plant defense mechanism. Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. PTM: This is a cyclic peptide which contains three disulfide bonds 4-21; 8-23; 13-28." No MICs found on DRAMP database Unknown 11524112 Phytochemistry. 2001 Sep;58(1):47-51. "Broussalis AM, G??ransson U, Coussio JD, Ferraro G, Martino V, Claeson P." First cyclotide from Hybanthus (Violaceae). DRAMP00884 SISCGESCVYIPCTVTALVGCTCKDKVCYLN 31 Cyclotide hyfl-A (Plant defensin) P84647 Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28." No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00885 GSPIQCAETCFIGKCYTEELGCTCTAFLCMKN 32 Cyclotide hyfl-B (Plant defensin) P84648 Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is is a cyclic peptide which may contain three disulfide bonds 6-22; 10-24; 15-29." No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00886 GSPRQCAETCFIGKCYTEELGCTCTAFLCMKN 32 Cyclotide hyfl-C (Plant defensin) P84649 Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is is a cyclic peptide which may contain three disulfide bonds 4-21; 8-23; 13-28." No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00887 GSVPCGESCVYIPCFTGIAGCSCKSKVCYYN 31 Cyclotide hyfl-D (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00888 GEIPCGESCVYLPCFLPNCYCRNHVCYLN 29 Cyclotide hyfl-E (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00889 SISCGETCTTFNCWIPNCKCNHHDKVCYWN 30 Cyclotide hyfl-F (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00890 CAETCVVLPCFIVPGCSCKSSVCYFN 26 Cyclotide hyfl-G (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00891 CAETCIYIPCFTEAVGCKCKDKVCYKN 27 Cyclotide hyfl-H (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00892 GIPCGESCVFIPCISGVIGCSCKSKVCYRN 30 Cyclotide hyfl-I (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00893 GIACGESCAYFGCWIPGCSCRNKVCYFN 28 Cyclotide hyfl-J (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00894 GTPCGESCVYIPCFTAVVGCTCKDKVCYLN 30 Cyclotide hyfl-K (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00895 GTPCAESCVYLPCFTGVIGCTCKDKVCYLN 30 Cyclotide hyfl-L (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00896 GNIPCGESCIFFPCFNPGCSCKDNLCYYN 29 Cyclotide hyfl-M (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00897 CGETCVILPCISAALGCSCKDTVCYKN 27 Cyclotide hyfl-N (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00898 CGETCVIFPCISAAFGCSCKDTVCYKN 27 Cyclotide hyfl-O (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00899 CVWIPCISGIAGCSCKNKVCYLN 23 Cyclotide hyfl-P (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus floribundus (Greenviolet) Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Function: Probably participates in a plant defense mechanism. No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00900 CGETCLFIPCIFSVVGCSCSSKVCYRN 27 Hymo A (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus monopetalus Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00901 CGETCVTGTCYTPGCACDWPVCKRD 25 Hymo B (Plant defensin) No entry found Belongs to the cyclotide family Unknown Hybanthus monopetalus Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00902 CGETCIWGRCYSENIGCHCGFGICTLN 27 Hyst A (Plant defensin) No entry found Belongs to the cyclotide family Unknown Australian Hybanthusstellarioides Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00903 RGCYKICGETCLFIPCLTSVFGCSCKN 27 Hyve A (Plant defensin) No entry found Belongs to the cyclotide family Unknown Australian Hybanthus vernonii Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00904 CGETCVVDTRCYTKKCSCAWPVCMRN 26 Hyca A (Plant defensin) No entry found Belongs to the cyclotide family Unknown Australian Hybanthus calycinus Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00905 CVWIPCISAAIGCSCKSKVCYRN 23 Hyde A (Plant defensin) No entry found Belongs to the cyclotide family Unknown Australian Hybanthus debilissimus Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00906 CGESCVYIPCTVTALLGCSCKDKVCYKN 28 Hyen A (Plant defensin) No entry found Belongs to the cyclotide family Unknown Australian Hybanthus enneaspermus Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00907 CGETCKVTKRCSGQGCSCLKGRSCYD 26 Hyen B (Plant defensin) No entry found Belongs to the cyclotide family Unknown Australian Hybanthus enneaspermus Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00908 CGETCVVLPCFIVPGCSCKSSVCYFN 26 Hyep A (Plant defensin) No entry found Belongs to the cyclotide family Unknown Australian Hybanthus epacroides Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00909 CGETCIYIPCFTEAVGCKCKDKVCYKN 27 Hyep B (Plant defensin) No entry found Belongs to the cyclotide family Unknown Australian Hybanthus epacroides Unkonw Bridge Cyclotides are plant-derived miniproteins that have the unusual features of a head-to-tail cyclized peptide backbone and a knotted arrangement of disulfide bonds. Unknown Caution: The sequence is incomplete! No MICs found on DRAMP database Unknown 16199617 Plant Cell. 2005 Nov;17(11):3176-3189. "Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, G??ransson U, Craik DJ." A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). DRAMP00910 GGTIFDCGESCFLGTCYTKGCSCGEWKLCYGTN 33 Tricyclon-A (Cyclotides; Plant defensin) P0C589 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Unkonw Beta strand (3 strands; 13 residues) Unknown 1YP8 resolved by NMR. "Function: Probably participates in a plant defense mechanism. Has a weak hemolytic activity. PTM: Contains three disulfide bonds 7-21; 11-23; 16-29. Proteolytically processed in two steps to yield first two linear precursors, and then two cyclic peptides after removal of the N-terminal repeats (NTR) and short tails." Cytolysis Unknown 15893660 Structure. 2005 May;13(5):691-701. "Mulvenna JP, Sando L, Craik DJ." Processing of a 22 kDa precursor protein to produce the circular protein tricyclon A. DRAMP00911 GGTIFDCGESCFLGTCYTKGCSCGEWKLCYGEN 33 Tricyclon-B (Plant defensin) P0C589 Belongs to the cyclotide family Unknown Viola arvensis (European field pansy) (Field violet) Unkonw Bridge Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has a weak hemolytic activity. PTM: Problely contains three disulfide bonds 7-21; 11-23; 16-29. Proteolytically processed in two steps to yield first two linear precursors, and then two cyclic peptides after removal of the N-terminal repeats (NTR) and short tails." Cytolysis Unknown 15893660 Structure. 2005 May;13(5):691-701. "Mulvenna JP, Sando L, Craik DJ." Processing of a 22 kDa precursor protein to produce the circular protein tricyclon A. DRAMP00912 GIPCAESCVWIPCTVTALLGCSCSNKVCYN 30 Root cyclotide 1 (Vhr1; Plant defensin) P83937 Belongs to the cyclotide family Unknown Viola hederacea (Australian violet) Unkonw Combine helix and strand structure Unknown 1VB8 resolved by NMR. "Function: Probably participates in a plant defense mechanism. Tissue specificity: Expressed in roots. PTM: Contains three disulfide bonds 4-21; 8-23; 13-28. This is a cyclic peptide (cross-link at G1-N30)." No MICs found on DRAMP database Unknown 15295104 Plant Cell. 2004 Aug;16(8):2204-2216. "Trabi M, Craik DJ." Tissue-specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1. DRAMP00913 GLPVCGETCFGGTCNTPGCSCSYPICTRN 29 Cyclotide vibi-A (Plant defensin) P85239 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism and shows potent cytotoxic activity. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26. This is a cyclic peptide (cross-link between G1-N29)." No MICs found on DRAMP database Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00914 GLPVCGETCFGGTCNTPGCTCSYPICTRN 29 Cyclotide vibi-B (Plant defensin) P85240 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism and shows potent cytotoxic activity. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26. This is a cyclic peptide (cross-link between G1-N29). Note: Sequence uncertainty at position 2 (L or I)." No MICs found on DRAMP database Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00915 GLPVCGETCAFGSCYTPGCSCSWPVCTRN 29 Cyclotide vibi-C (Plant defensin) P85241 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism and shows potent cytotoxic activity. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26. This is a cyclic peptide (cross-link between G1-N29)." No MICs found on DRAMP database Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00916 GLPVCGETCFGGRCNTPGCTCSYPICTRN 29 Cyclotide vibi-D (Plant defensin) P85242 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism. Has moderate levels of cytotoxic activity. PTM: Contains three disulfide bonds 5-21; 9-23; 14-28. This is a cyclic peptide (cross-link at G1-N29)." Human lymphoma cell line U-937 GTB (IC50>30 ?M). Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00917 GIPCAESCVWIPCTVTALIGCGCSNKVCYN 30 Cyclotide vibi-E (Vbc1; Plant defensin) "B1NRQ8, P85243" Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism. Has cytotoxic activity. PTM: Contains three disulfide bonds 4-21; 8-23; 13-28. This is a cyclic peptide (cross-link at G1-N3)." Human lymphoma cell line U-937 GTB (IC50=3.2 ?M). Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00918 GTIPCGESCVFIPCLTSALGCSCKSKVCYKN 31 Cyclotide vibi-F (Plant defensin) P85244 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism and shows potent cytotoxic activity. PTM: Contains three disulfide bonds 5-21; 9-23; 14-28. This is a cyclic peptide (cross-link at G1-N31)." No MICs found on DRAMP database Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00919 GTFPCGESCVFIPCLTSAIGCSCKSKVCYKN 31 Cyclotide vibi-G (Plant defensin) P85245 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism. Has cytotoxic activity. PTM: Contains three disulfide bonds 5-21; 9-23; 14-28. This is a cyclic peptide (cross-link at G1-N31)." Human lymphoma cell line U-937 GTB (IC50=0.96 ?M). Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00920 GLLPCAESCVYIPCLTTVIGCSCKSKVCYKN 31 Cyclotide vibi-H (Plant defensin) P85246 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism. Has cytotoxic activity. PTM: Contains three disulfide bonds 5-21; 9-23; 14-28. This is a cyclic peptide (cross-link at G1-N31)." Human lymphoma cell line U-937 GTB (IC50=1.6 ?M). Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00921 GIPCGESCVWIPCLTSTVGCSCKSKVCYRN 30 Cyclotide vibi-I (Vbc2; Plant defensin) B1NRQ9 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism. PTM: Contains three disulfide bonds 4-20; 8-22; 13-27. This is a cyclic peptide (cross-link at G1-N30)." No MICs found on DRAMP database Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00922 GTFPCGESCVWIPCISKVIGCACKSKVCYKN 31 Cyclotide vibi-J (Vbc3; Plant defensin) B1NRR0 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism and shows potent cytotoxic activity. PTM: Contains three disulfide bonds 5-21; 9-23; 14-28. This is a cyclic peptide (cross-link at G1-N31)." No MICs found on DRAMP database Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00923 GIPCGESCVWIPCLTSAVGCPCKSKVCYRN 30 Cyclotide vibi-K (Vbc4; Plant defensin) B1NRR1 Belongs to the cyclotide family Unknown Viola biflora (Yellow wood violet) Cytotoxic Bridge "The cyclotides are head-to-tail macrocyclic and they have three disulfides arranged in a cystine knot, in which two disulfide bonds and their connecting backbone segments form an embedded ring that is penetrated by the third disulfide bond. Cyclotides exhibit a broad range of biological effects, including insecticidal, haemolytic, and cytotoxic effects." Unknown "Function: Probably participates in a plant defense mechanism and shows potent cytotoxic activity. PTM: Contains three disulfide bonds 4-20; 8-22; 13-27. This is a cyclic peptide (cross-link at G1-N31)." No MICs found on DRAMP database Unknown 18191970 Phytochemistry. 2008 Feb;69(4):939-952. "Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, G??ransson U." "The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity." DRAMP00924 PGLGFY 6 Cyclopeptide E (Plant defensin) P85003 Unknown Unknown Annona cherimola (Custard apple) (Cherimoya) Cytotoxic Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: This is a cyclic peptide." Human nasopharyngeal carcinoma (IC50=60 nM). Unknown 16040066 Phytochemistry. 2005 Oct;66(19):2376-2380. "W??l?? A, Zhang Y, Brouard JP, Pousset JL, Bodo B." Two cyclopeptides from the seeds of Annona cherimola. DRAMP00925 PGMGIYLPM 9 Cyclopeptide F (Plant defensin) P85002 Unknown Unknown Annona cherimola (Custard apple) (Cherimoya) Cytotoxic Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. Has cytotoxic activity. PTM: This is a cyclic peptide." Human nasopharyngeal carcinoma (IC50=60 nM). Unknown 16040066 Phytochemistry. 2005 Oct;66(19):2376-2380. "W??l?? A, Zhang Y, Brouard JP, Pousset JL, Bodo B." Two cyclopeptides from the seeds of Annona cherimola. DRAMP00926 SAISCGETCFKFKCYTPRCSCSYPVCK 27 Violacin-A (Violacin-1; linearized uncyclotides; Plant defensin) Q2HY54 Unknown Unknown Viola odorata (Sweet violet) Antimicrobial Beta strand (4 strands; 9 residues) The three-dimensional solution structure of violacin A is determined and found to adopt the cystine knot fold of native cyclotides. (Ref.2) 2FQA resolved by NMR. "Function: Probably participates in a plant defense mechanism. Has low hemolytic activity. Miscellaneous: The presence of a premature stop codon inhibits the translation of a key Asn residue that is thought to be required for cyclization. PTM: Contains three disulfide bonds 5-19; 9-21; 14-26." No MICs found on DRAMP database Unknown 16872274##16488428 Biochem J. 2006 Nov 15;400(1):1-12.##J Mol Biol. 2006 Apr 14;357(5):1522-1535. "Ireland DC, Colgrave ML, Craik DJ.##Ireland DC, Colgrave ML, Nguyencong P, Daly NL, Craik DJ." "A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability..##Discovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins." DRAMP00927 GSIPCAESCVYIPCFTGIAGCSCKNKVCYYN 31 Cyclotide vico-A (Plant defensin) P84635 Unknown Unknown Viola cotyledon (Violeta) Antimicrobial Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Problely contains three disulfide bonds 5-21; 9-23; 14-28. This is a cyclic peptide (cross-link at G1-N31)." No MICs found on DRAMP database Unknown 12782038 Anal Biochem. 2003 Jul 1;318(1):107-117. "G??ransson U, Broussalis AM, Claeson P." Expression of Viola cyclotides by liquid chromatography-mass spectrometry and tandem mass spectrometry sequencing of intercysteine loops after introduction of charges and cleavage sites by aminoethylation. DRAMP00928 GSIPCAESCVYIPCITGIAGCSCKNKVCYYN 31 Cyclotide vico-B (Plant defensin) P84636 Unknown Unknown Viola cotyledon (Violeta) Antimicrobial Unknown Unknown Unknown "Function: Probably participates in a plant defense mechanism. PTM: Problely contains three disulfide bonds 5-21; 9-23; 14-28. This is a cyclic peptide (cross-link at G1-N31)." No MICs found on DRAMP database Unknown 12782038 Anal Biochem. 2003 Jul 1;318(1):107-117. "G??ransson U, Broussalis AM, Claeson P." Expression of Viola cyclotides by liquid chromatography-mass spectrometry and tandem mass spectrometry sequencing of intercysteine loops after introduction of charges and cleavage sites by aminoethylation. DRAMP00932 SYFSAWAGPGCNNHNARYSKCGCSNIGHNVHGGYEFVYQGQTAAAYNTDNCKGVAQTRFSSSVNQACSNFGWKSVFIQC 79 Antimicrobial peptide 1 (PMAP1; Plant defensin) "P83880, Q2M5E6" Unknown Unknown Pinus monticola (Western white pine) (Strobus monticola) "Antibacterial, Antifungal" Bridge Unknown Unknown "Tissue specificity: Detected at higher levels in needles and twigs from canker-resistant seedlings than in needles from canker-susceptible plants. During summer, detected on cankered, healthy and marginal bark. During winter, detected at lower levels in cankered bark and bark from the canker margin than in healthy bark (at protein level). Developmental stage: In summer, present at higher levels in older needles and twigs than in tissues from the current year. In winter, detected at high levels in both older and current-year needles and twigs. Induction: By wounding and by methyl jasmonate. PTM: Problely contains three disulfide bonds 11-67; 21-79; 23-51." No MICs found on DRAMP database Unknown 18943919##14759906 Phytopathology. 2006 Feb;96(2):164-170.##Tree Physiol. 1997 Oct;17(10):663-669. "Ekramoddoullah AK, Liu JJ, Zamani A.##Davidson J, Ekramoddoullah AK." Cloning and Characterization of a Putative Antifungal Peptide Gene (Pm-AMP1) in Pinus monticola.##Analysis of bark proteins in blister rust-resistant and susceptible western white pine (Pinus monticola). DRAMP00934 RTCESQSHRFKGTCVRQSNCAAVCQTEGFHGGNCRGFRRRCFCTKHC 47 Vv-AMP1 (Vitis vinifera antimicrobial peptide 1; Plant defensin) No entry found Unknown Unknown Vitis vinifera (Berry) Antifungal Unknown Unknown Unknown MOA: the inhibitory activity of Vv-AMP1 might be associated with altering the membrane permeability of the fungal membranes. Fungi: Fusarium oxysporum and Verticillium dahliae. Unknown 18611251 BMC Plant Biol. 2008 Jul 8;8:75. "de Beer A, Vivier MA." "Vv-AMP1, a ripening induced peptide from Vitis vinifera shows strong antifungal activity." DRAMP00935 DVSFSLSGGGTASYEK 16 Ribosome-inactivating protein trichokirin (rRNA N-glycosidase; Plant defensin) P16093 Belongs to the ribosome-inactivating protein family (Type 1 RIP subfamily) Unknown Trichosanthes kirilowii (Chinese snake gourd) (Chinese cucumber) Cytotoxic Unknown Unknown Unknown "Catalytic activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA. PTM: Glycosylated." No MICs found on DRAMP database Unknown 3262509 Eur J Biochem. 1988 Oct 1;176(3):581-588. "Casellas P, Dussossoy D, Falasca AI, Barbieri L, Guillemot JC, Ferrara P, Bolognesi A, Cenini P, Stirpe F." "Trichokirin, a ribosome-inactivating protein from the seeds of Trichosanthes kirilowii Maximowicz. Purification, partial characterization and use for preparation of immunotoxins." DRAMP00936 DVSFRLSGATSKKKVYFISNLRKALPNEKKLYDIPLVRSSXSGSK 45 Ribosome-inactivating protein TAP-29 (rRNA N-glycosidase; Plant defensin) P23029 Belongs to the ribosome-inactivating protein family (Type 1 RIP subfamily) Unknown Trichosanthes kirilowii (Chinese snake gourd) (Chinese cucumber) "Antiviral, Cytotoxic" Unknown Unknown Unknown "Function: Capable of inhibiting HIV-1 infection and replication. It inactivates eukaryotic 60S ribosomal subunits. Catalytic activity: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA." No MICs found on DRAMP database Unknown 1713684 Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6570-4. "Lee-Huang S, Huang PL, Kung HF, Li BQ, Huang PL, Huang P, Huang HI, Chen HC." TAP 29: an anti-human immunodeficiency virus protein from Trichosanthes kirilowii that is nontoxic to intact cells. DRAMP00937 KSCCRNTVARNCYNVCRIPGTPRPVCAATCDCKLITGTKCPPGYEK 46 Tu-AMP1 (Plant defensin) No entry found Belongs to the thionin family Unknown Tulipa gesneriana L. "Antibacterial, Antifungal" Unknown Unknown Unknown No comments found on DRAMP database "Gram-negative bacteria: Bacteria: Erwinia carotovora (IC50=11 ?g/ml), Agrobacterium radiobacter (IC50=15 ?g/ml), Agrobacterium rhizogenes (IC50=20 ?g/ml);##Gram-positive bacteria: Clavibacter michiganensis (IC50=14 ?g/ml), Curtobacterium flaccumfaciens (IC50=13 ?g/ml).##Fungi: Fusarium oxysporum (IC50=2 ?g/ml), Geotrichum candidum (IC50=2 ?g/ml)." Chitin-binding 15056889 Biosci Biotechnol Biochem. 2004 Mar;68(3):571-577. "Fujimura M, Ideguchi M, Minami Y, Watanabe K, Tadera K." "Purification, characterization, and sequencing of novel antimicrobial peptides, Tu-AMP 1 and Tu-AMP 2, from bulbs of tulip (Tulipa gesneriana L.)." DRAMP00938 KSCCRNTTARNCYNVCRIPG 20 Tu-AMP2 (Plant defensin) No entry found Belongs to the thionin family Unknown Tulipa gesneriana L. "Antibacterial, Antifungal" Unknown Unknown Unknown No comments found on DRAMP database "Gram-negative bacteria: Erwinia carotovora (IC50=15 ?g/ml), Agrobacterium radiobacter (IC50=17 ?g/ml), Agrobacterium rhizogenes (IC50=20 ?g/ml);##Gram-positive bacteria: Clavibacter michiganensis (IC50=17 ?g/ml), Curtobacterium flaccumfaciens (IC50=15 ?g/ml).##Fungi: Fusarium oxysporum (IC50=2 ?g/ml), Geotrichum candidum (IC50=2 ?g/ml)." Unknown 15056889 Biosci Biotechnol Biochem. 2004 Mar;68(3):571-577. "Fujimura M, Ideguchi M, Minami Y, Watanabe K, Tadera K." "Purification, characterization, and sequencing of novel antimicrobial peptides, Tu-AMP 1 and Tu-AMP 2, from bulbs of tulip (Tulipa gesneriana L.)." DRAMP00939 VDCGANPFKVACFNSCLLGPSTVFQCADFCACRLPAG 37 Type-5 thionin (Type V thionin; Plant defensin) Q05806 Belongs to the thionin family TTHV Triticum aestivum (Wheat) Cytotoxic Unknown Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains three disulfide bonds 3-40; 12-30; 16-26. " No MICs found on DRAMP database Unknown 1569564 J Mol Biol. 1992 Apr 20;224(4):1003-1009. "Castagnaro A, Mara?㊣a C, Carbonero P, Garc??a-Olmedo F." Extreme divergence of a novel wheat thionin generated by a mutational burst specifically affecting the mature protein domain of the precursor. DRAMP00940 TTCCPSIVARSNFNVCRLPGTPEALCATYTGCIIIPGATCPGDYAN 46 Crambin (Plant defensin) P01542 Belongs to the thionin family THI2 Crambe hispanica subsp. abyssinica (Abyssinian kale) (Crambe abyssinica) Cytotoxic Combine helix and strand structure Unknown 3NIR resolved by X-ray. "Function: The Function: of this hydrophobic plant seed protein is not known. Miscellaneous: Two isoforms exists, a major form PL (shown here) and a minor form SI. PTM: Contains three disulfide bonds 3-40; 4-32; 16-26." No MICs found on DRAMP database Unknown 6895315##21505232 Biochemistry. 1981 Sep 15;20(19):5437-5443.##Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Apr 1;67(Pt 4):424-428. "Teeter MM, Mazer JA, L'Italien JJ.##Schmidt A, Teeter M, Weckert E, Lamzin VS." Primary structure of the hydrophobic plant protein crambin.##Crystal structure of small protein crambin at 0.48#?# resolution. DRAMP00941 KSCCRNTLARNCYNACRFTGGSQPTCGILCDCIHVTTTTCPSSHPS 46 Hellethionin-D (Plant defensin) P60057 Belongs to the thionin family Unknown Helleborus purpurascens (Purple hellebore) Cytotoxic Combine helix and strand structure Unknown 1NBL resolved by NMR. "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains four disulfide bonds 3-40; 4-32; 12-30; 16-26. " No MICs found on DRAMP database Unknown 12600207 Biochemistry. 2003 Mar 4;42(8):2404-2411. "Milbradt AG, Kerek F, Moroder L, Renner C." Structural characterization of hellethionins from Helleborus purpurascens. DRAMP00942 KSCCRTTLGRNCYNLCRSRGAQKLCSTVCRCKLTSGLSCPKGFPK 45 Alpha-2-purothionin (Plant defensin) P32032 Belongs to the thionin family THI1.2 Triticum aestivum (Wheat) Cytotoxic Bridge Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Problely contains four disulfide bonds 3-39; 5-31; 12-29; 16-25. " No MICs found on DRAMP database Unknown 7824649 Plant Physiol. 1994 Nov;106(3):1221-1222. "Castagnaro A, Mara?㊣a C, Carbonero P, Garc??a-Olmedo F." cDNA cloning and nucleotide sequences of alpha 1 and alpha 2 thionins from hexaploid wheat endosperm. DRAMP00943 KSCCRSTLGRNCYNLCRARGAQKLCAGVCRCKISSGLSCPKGFPK 45 Alpha-1-purothionin (Plant defensin) P01544 Belongs to the thionin family THI1.1 Triticum aestivum (Wheat) Cytotoxic Combine helix and strand structure Unknown 2PLH resolved by X-ray. "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise Function: is not known. PTM: Contains four disulfide bonds 3-39; 4-31; 12-29; 16-25. " No MICs found on DRAMP database Unknown 7824649##2235992 Plant Physiol. 1994 Nov;106(3):1221-1222.##Proteins. 1990;8(2):118-132. "Castagnaro A, Mara?㊣a C, Carbonero P, Garc??a-Olmedo F.##Teeter MM, Ma XQ, Rao U, Whitlow M." cDNA cloning and nucleotide sequences of alpha 1 and alpha 2 thionins from hexaploid wheat endosperm.##Crystal structure of a protein-toxin alpha 1-purothionin at 2.5A and a comparison with predicted models. DRAMP00944 KSCCKSTLGRNCYNLCRARGAQKLCANVCRCKLTSGLSCPKDFPK 45 Purothionin A-1 (Plant defensin) P01543 Belongs to the thionin family THI1.3 Triticum aestivum (Wheat) Cytotoxic Combine helix and strand structure Unknown 1BHP resolved by X-ray. Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. No MICs found on DRAMP database Unknown 15299761 Acta Crystallogr D Biol Crystallogr. 1995 Nov 1;51(Pt 6):914-924. "Stec B, Rao U, Teeter MM." Refinement of purothionins reveals solute particles important for lattice formation and toxicity. Part 2: structure of beta-purothionin at 1.7 A resolution. DRAMP00945 KSCCPTTTARNIYNTCRFGGGSRPVCAKLSGCKIISGTKCDSGWNH 46 Phoratoxin (Plant defensin) P01539 Belongs to the thionin family Unknown Phoradendron tomentosum (California mistletoe) Cytotoxic Unknown Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise function is not known. PTM: Contains three disulfide bonds 3-40; 4-32; 16-26." No MICs found on DRAMP database Unknown 4606908 Acta Pharm Suec. 1974 Sep;11(4):367-374. "Mellstrand ST, Samuelsson G." "Phoratoxin, a toxic protein from the mistletoe Pharoadendron tomentosum subsp. macrophyllum (Loranthaceae). The disulphide bonds." DRAMP00946 QKIPFKECYPACLVECKAGSKFPKYLKCPFTCTKECLQQPSPPSVSSNNIDESDYFCKLGCATYHCVSLSSIQNPNVERVSACVDSCSNKCTKKN 95 Thionin-like protein 2 (Plant defensin) A8MRP4 Belongs to the thionin family Unknown Arabidopsis thaliana (Mouse-ear cress) Unkonw Unknown Unknown Unknown Function: May be involved in plant defense. No MICs found on DRAMP database Unknown 11130712 Nature. 2000 Dec 14;408(6814):816-820. "Theologis A, Ecker JR, Palm CJ, et al." Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. DRAMP00947 KSCCPTTAARNQYNICRLPGTPRPVCAALSGCKIISGTGCPPGYRH 46 Denclatoxin-B (Plant defensin) P01541 Belongs to the thionin family Unknown Dendrophthora clavata (Columbian mistletoe) Cytotoxic Unknown Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Problely contains three disulfide bonds 3-40; 4-32; 16-26." No MICs found on DRAMP database Unknown 906843 Acta Pharm Suec. 1977;14(3):245-254. "Samuelsson G, Pettersson B." Toxic proteins from the mistletoe Dendrophtora clavata. II. The amino acid sequence of denclatoxin B. DRAMP00948 KSCCPSTTARNIYNTCRLTGTSRPTCASLSGCKIISGSTCBSGWBH 46 Ligatoxin-A (Plant defensin) P01540 Belongs to the thionin family Unknown Phoradendron liga (Argentine mistletoe) Cytotoxic Unknown Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains three disulfide bonds 3-40; 4-32; 16-26." No MICs found on DRAMP database Unknown 7136736 Acta Pharm Suec. 1982;19(4):285-292. "Thunberg E, Samuelsson G." "Isolation and properties of ligatoxin A, a toxic protein from the mistletoe Phoradendron liga." DRAMP00949 KSCCPSTTARNIYNTCRLTGASRSVCASLSGCKIISGSTCDSGWNH 46 Ligatoxin-B (Plant defensin) P59358 Belongs to the thionin family Unknown Phoradendron liga (Argentine mistletoe) Cytotoxic Unknown Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains three disulfide bonds 3-40;4-32;16-26." Human lymphoma cell line U-937-GTB (IC50=1.8 ?M);##primary multidrug-resistant renal adenocarcinoma cell line ACHN (IC50=3.2 ?M). Unknown 12049612 Biochem J. 2002 Sep 1;366(Pt 2):405-413. "Li SS, Gullbo J, Lindholm P, Larsson R, Thunberg E, Samuelsson G, Bohlin L, Claeson P." "Ligatoxin B, a new cytotoxic protein with a novel helix-turn-helix DNA-binding domain from the mistletoe Phoradendron liga." DRAMP00950 KSCCPBTTGRBIYBTCRFGGGSRZVCARISGCKIISASTCPSYPBK 46 Viscotoxin-1-PS (Vt1-PS; Plant defensin) P01537 Belongs to the thionin family THI2.4 Viscum album (European mistletoe) Cytotoxic Bridge Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains three disulfide bonds 3-40; 4-32; 16-26. " No MICs found on DRAMP database Unknown 4417993 Acta Pharm Suec. 1974 May;11(2):175-184. "Samuelsson G, Jayawardene AL." "Isolation and characterization of viscotoxin 1-Ps from Viscum album L. ssp. austriacum (Wiesb.) vollmann, growing on Pinus silvestris." DRAMP00951 KSCCPNTTGRNIYNACRLTGAPCPTCAKLSGCKIISGSTCPSDYPK 46 Viscotoxin A (Plants; Predicted) Q9S9A2 Unknown Unknown Viscum album (European mistletoe) Antimicrobial Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 8292787 Plant Mol Biol. 1993 Dec;23(6):1233-1242. "Schrader-Fischer G, Apel K." cDNA-derived identification of novel thionin precursors in Viscum album that contain highly divergent thionin domains but conserved signal and acidic polypeptide domains. DRAMP00952 KSCCPNTTGRNIYNTCRLTGSSRETCAKLSGCKIISASTCPSNYPK 46 Viscotoxin A1 (Plant defensin) D0VWT3 Unknown Unknown Viscum album (European mistletoe) "Antibacterial, Antifungal, Antiviral, Anticancer" Combine helix and strand structure Unknown 3C8P resolved by X-ray. No comments found on DRAMP database No MICs found on DRAMP database Unknown 18703848 Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):985-992. "Pal A, Debreczeni JE, Sevvana M, Gruene T, Kahle B, Zeeck A, Sheldrick GM." Structures of viscotoxins A1 and B2 from European mistletoe solved using native data alone. DRAMP00953 KSCCPNTTGRNIYNTCRFGGGSREVCASLSGCKIISASTCPSYPDK 46 Viscotoxin-A2 (VtA2; Plant defensin) "P32880, P01536" Belongs to the thionin family THI2.3 Viscum album (European mistletoe) Cytotoxic Combine helix and strand structure Unknown 1JMN resolved by NMR. "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains three disulfide bonds 3-40; 4-32; 16-26. " No MICs found on DRAMP database Unknown 4607177##12733989 Acta Pharm Suec. 1974 Sep;11(4):381-386.##Biochem J. 2003 Aug 15;374(Pt 1):71-78. "Olson T, Samuelsson G.##Coulon A, Mosbah A, Lopez A, Sautereau AM, Schaller G, Urech K, Roug?? P, Darbon H." "The disulphide bonds of viscotoxin A2 from the European mistletoe (Viscum album L. Loranthaceae).##Comparative membrane interaction study of viscotoxins A3, A2 and B from mistletoe (Viscum album) and connections with their structures." DRAMP00954 KSCCPNTTGRNIYNACRLTGAPRPTCAKLSGCKIISGSTCPSDYPK 46 Viscotoxin-A3 (Plant defensin) P01538 Belongs to the thionin family THI2.1 Viscum album (European mistletoe) "Antifungal, Cytotoxic" Combine helix and strand structure Unknown 1OKH resolved by X-ray. "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains three disulfide bonds 3-40; 4-32; 16-26. " "Fungi: Fusarium solani, Sclerotinia sclerotiorum, Phytophtora infestans." Cell membrance 1710983##4941626##10947973 Eur J Biochem. 1991 Jun 15;198(3):549-553.##Acta Chem Scand. 1971;25(6):2048-2054.##Biochem J. 2000 Sep 1;350 Pt 2:569-577. "Schrader G, Apel K.##Samuelsson G, Pettersson B.##Romagnoli S, Ugolini R, Fogolari F, Schaller G, Urech K, Giannattasio M, Ragona L, Molinari H." "Isolation and characterization of cDNAs encoding viscotoxins of mistletoe (Viscum album).##The disulfide bonds of viscotoxin A3 from the European mistletoe (Viscum album L., Loranthaceae).##NMR structural determination of viscotoxin A3 from Viscum album L." DRAMP00955 KSCCPNTTGRNIYNTCRLGGGSRERCASLSGCKIISASTCPSDYPK 46 Viscotoxin-B (VtB; Plant defensin) "P08943, P01536, P84186" Belongs to the thionin family THI2.2 Viscum album (European mistletoe) "Antifungal, Cytotoxic" Combine helix and strand structure Unknown 1JMP resolved by NMR.##2V9B resolved by X-ray. "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise Function: is not known. PTM: Contains three disulfide bonds 3-40; 4-32; 16-26." "Fungi: Fusarium solani, Sclerotinia sclerotiorum, Phytophtora infestans." Unknown 1710983##12733989 Eur J Biochem. 1991 Jun 15;198(3):549-553.##Biochem J. 2003 Aug 15;374(Pt 1):71-78. "Schrader G, Apel K.##Coulon A, Mosbah A, Lopez A, Sautereau AM, Schaller G, Urech K, Roug?? P, Darbon H." "Isolation and characterization of cDNAs encoding viscotoxins of mistletoe (Viscum album).##Comparative membrane interaction study of viscotoxins A3, A2 and B from mistletoe (Viscum album) and connections with their structures." DRAMP00956 KSCCPNTTGRNIYNTCRFAGGSRERCAKLSGCKIISASTCPSDYPK 46 Viscotoxin-C1 (VtC1; Plant defensin) P83554 Belongs to the thionin family Unknown Viscum album (European mistletoe) Cytotoxic Combine helix and strand structure Unknown 1ORL resolved by NMR.##3C8P resolved by X-ray. "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise Function: is not known. PTM: Contains three disulfide bonds 3-40; 4-32; 16-26." No MICs found on DRAMP database Unknown 9348108##14580196 Biol Chem. 1997 Sep;378(9):989-996.##Biochemistry. 2003 Nov 4;42(43):12503-10. "Orr?? S, Scaloni A, Giannattasio M, Urech K, Pucci P, Schaller G.##Romagnoli S, Fogolari F, Catalano M, Zetta L, Schaller G, Urech K, Giannattasio M, Ragona L, Molinari H." "Amino acid sequence, S-S bridge arrangement and distribution in plant tissues of thionins from Viscum album.##NMR solution structure of viscotoxin C1 from Viscum album species Coloratum ohwi: toward a structure-Function: analysis of viscotoxins." DRAMP00957 KSCCRSTQARNIYNAPRFAGGSRPLCALGSGCKIVDDKKTPPND 44 Pp-AMP1 (P. pubescens AMP1; Plant defensin) No entry found Belongs to the thionin family Unknown Phyllostachys pubescens (Japanese bamboo shoots) "Antibacterial, Antifungal" Bridge Unknown Unknown No comments found on DRAMP database "Gram-negative bacteria: Erwinia carotovora (IC50=22 ?g/ml), Agrobacterium radiobacter (IC50=15 ?g/ml), Agrobacterium rhizogenes (IC50=15 ?g/ml);##Gram-positive bacteria: Clavibacter michiganensis (IC50=14 ?g/ml), Curtobacterium flaccumfaciens (IC50=25 ?g/ml).##Fungi: Fusarium oxysporum (IC50=2 ?g/ml), Geotrichum candidum (IC50=2 ?g/ml)." Chitin-binding 15784998 Biosci Biotechnol Biochem. 2005 Mar;69(3):642-645. "Fujimura M, Ideguchi M, Minami Y, Watanabe K, Tadera K." "Amino acid sequence and antimicrobial activity of chitin-binding peptides, Pp-AMP 1 and Pp-AMP 2, from Japanese bamboo shoots (Phyllostachys pubescens)." DRAMP00958 KSCCRSTTARNIYNGCRVPGTARPVCAKKSGCKIQEAKKCEPPYD 45 Pp-AMP2 (P. pubescens AMP2; Plant defensin) No entry found Belongs to the thionin family Unknown Phyllostachys pubescens (Japanese bamboo shoots) "Antibacterial, Antifungal" Bridge Unknown Unknown No comments found on DRAMP database "Gram-negative bacteria: Erwinia carotovora (IC50=20 ?g/ml), Agrobacterium radiobacter (IC50=13 ?g/ml), Agrobacterium rhizogenes (IC50=15 ?g/ml);##Gram-positive bacteria: Clavibacter michiganensis (IC50=18 ?g/ml), Curtobacterium flaccumfaciens (IC50=20 ?g/ml).##Fungi: Fusarium oxysporum (IC50=2 ?g/ml), Geotrichum candidum (IC50=2 ?g/ml)." Chitin-binding 15784998 Biosci Biotechnol Biochem. 2005 Mar;69(3):642-645. "Fujimura M, Ideguchi M, Minami Y, Watanabe K, Tadera K." "Amino acid sequence and antimicrobial activity of chitin-binding peptides, Pp-AMP 1 and Pp-AMP 2, from Japanese bamboo shoots (Phyllostachys pubescens)." DRAMP00959 KICRRRSAGFKGPCMSNKNCAQVCQQEQWQQQNCDQPFRRCKCIRQC 47 Gamma1-purothionin (gamma1-P; thionin-like polypeptides; Plant defensin) No entry found Belongs to the thionin family Unknown Triticum turgidum L cv Senatore Capelli (wheat endosperm) Unkonw Beta strand Unknown Unknown PTM: Contains four disulfide bonds. No MICs found on DRAMP database Unknown 2226781 FEBS Lett 1990; 270: 191-194. "Colilla FJ, Rocher A, Mensez E." Gamma-purothionins: amino acid sequence of two polypeptides of a new family of thionins from wheat endosperm. DRAMP00960 KVCRQRSAQFKGPCVSDKNCAQVCLQEQWQQQNCDQPFRRCKCIRQC 47 Gamma2-purothionin (gamma2-P; thionin-like polypeptides; Plant defensin) No entry found Belongs to the thionin family Unknown Triticum turgidum L cv Senatore Capelli (wheat endosperm) Unkonw Unknown Unknown Unknown PTM: Contains four disulfide bonds. No MICs found on DRAMP database Unknown 2226781 FEBS Lett 1990; 270: 191-194. "Colilla FJ, Rocher A, Mensez E." Gamma-purothionins: amino acid sequence of two polypeptides of a new family of thionins from wheat endosperm. DRAMP00961 KSCCRNTWARNCYNVCRLPGTISREICAKKCDCKIISGTTCPSDYPK 47 Thionin (Plant defensin) P07504 Belongs to the thionin family THI1 Pyrularia pubera (Buffalo nut) (Oil nut) Cytotoxic Bridge Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Toxic dose: At concentrations of 0.04 mg/ml the protein causes visible disruption of cultured mouse B16 melanoma cells. PTM: Contains three disulfide bonds 3-41; 4-31; 16-27 (By similarity)." No MICs found on DRAMP database Unknown 3985614 Arch Biochem Biophys. 1985 Apr;238(1):18-29. "Vernon LP, Evett GE, Zeikus RD, Gray WR." "A toxic thionin from Pyrularia pubera: purification, properties, and amino acid sequence." DRAMP00962 RNCESLSHRFKGPCTRDSNC 20 Pseudothionin Solanum tuberosum 1 (Pth-St1; Plant defensin) No entry found Belongs to the thionin family Unknown Solanum tuberosum (potato) Antibacterial Unknown Unknown Unknown No comments found on DRAMP database "Clavibacter michiganensis subspecies sepedonicus, Pseudomonas solanacearum and Fusarium solani." Unknown 8033886 Eur J Biochem. 1994 Jul 1;223(1):135-139. "Moreno M, Segura A, Garc??a-Olmedo F." " Pseudothionin-St1, a potato peptide active against potato pathogens." DRAMP00963 KSCCKNTTGRNCYNACRFAGGSRPVCATACGCKIISGPTCPRDYPK 46 Thionin BTH7 (Plant defensin) Q42838 Belongs to the thionin family Unknown Hordeum vulgare (Barley) Cytotoxic Bridge Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains four disulfide bonds 3-40;4-32;12-30;16-26. " No MICs found on DRAMP database Unknown PubMed ID is not available Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases "Holtorf S, Schuetz C, Apel K, Bohlmann H." Specific and distinct expression patterns of two members of the thionin multigene family of barley in transgenic tobacco. DRAMP00964 KICCPRTIDRNIYNACRLTGASMTNCANLSGCKIVSGTTCPPGYTH 46 Thionin (Plant defensin) Q9SBK8 Belongs to the thionin family THI2 Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis) Cytotoxic Unknown Unknown Unknown Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. No MICs found on DRAMP database Unknown PubMed ID is not available Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases "Lee S.Y, Cho M.J, Choi Y.O." Molecular cloning and characterization of flower specific thionin in Chinese cabbage. DRAMP00965 KSCCKNTTGRNCYNACHFAGGSRPVCATACGCKIISGPTCPRDYPK 46 Probable leaf thionin (Plant defensin) Q8H0Q5 Belongs to the thionin family Unknown Hordeum vulgare (Barley) Cytotoxic Bridge Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Problely contains four disulfide bonds 3-40; 4-32; 12-30; 16-26. " No MICs found on DRAMP database Unknown PubMed ID is not available Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases "Kah B, Kogel K.H, Langen G." ORF of a leaf expressed barley thionin. DRAMP00966 KSCCKDTLARNCYNTCHFAGGSRPVCAGACRCKIISGPKCPSDYPK 46 Leaf-specific thionin DB4 (Hv-THDB4; Plant defensin) P08772 Belongs to the thionin family THI1.3 Hordeum vulgare (Barley) Cytotoxic Unknown Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Problely contains four disulfide bonds 3-40; 4-32; 12-30; 16-26. " No MICs found on DRAMP database Unknown PubMed ID is not available Mol. Gen. Genet. 207:446-454(1987) "Bohlmann H, Apel K." Isolation and characterization of cDNAs coding for leaf-specific thionins closely related to the endosperm-specific hordothionin of barley (Hordeum vulgare L.). DRAMP00967 KSCCKNTTGRNCYNACRFAGGSRPVCATACGCKIISGPTCPRDYPK 46 Leaf-specific thionin (Plant defensin) P09617 Belongs to the thionin family THI1.5 Hordeum vulgare (Barley) Cytotoxic Unknown Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Problely contains three disulfide bonds 3-40; 4-32; 16-26. " No MICs found on DRAMP database Unknown 1377959##16453847 Plant Mol Biol. 1992 May;19(2):193-204.##EMBO J. 1988 Jun;7(6):1559-1565. "Andresen I, Becker W, Schl??ter K, Burges J, Parthier B, Apel K.##Bohlmann H, Clausen S, Behnke S, Giese H, Hiller C, Reimann-Philipp U, Schrader G, Barkholt V, Apel K." The identification of leaf thionin as one of the main jasmonate-induced proteins of barley (Hordeum vulgare).##Leaf-specific thionins of barley-a novel class of cell wall proteins toxic to plant-pathogenic fungi and possibly involved in the defence mechanism of plants. DRAMP00968 KSCCKDTLARNCYNTCRFAGGSRPVCAGACRCKIISGPKCPSDYPK 46 Leaf-specific thionin BTH6 (Plant defensin) P09618 Belongs to the thionin family Unknown Hordeum vulgare (Barley) Antifungal Unknown Unknown Unknown "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains four disulfide bonds 3-40; 4-30; 12-26; 16-26." "Fungi: Thievaliopsis paradoxa, Drechslera teres." Unknown 16453847##PubMed ID is not available EMBO J. 1988 Jun;7(6):1559-1565.##Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases "Bohlmann H, Clausen S, Behnke S, Giese H, Hiller C, Reimann-Philipp U, Schrader G, Barkholt V, Apel K.##Holtorf S, Schuetz C, Apel K, Bohlmann H." Leaf-specific thionins of barley-a novel class of cell wall proteins toxic to plant-pathogenic fungi and possibly involved in the defence mechanism of plants.##Specific and distinct expression patterns of two members of the thionin multigene family of barley in transgenic tobacco. DRAMP00969 KSCCRSTLGRNCYNLCRVRGAQKLCAGVCRCKLTSSGKCPTGFPK 45 Alpha-hordothionin (alpha-HT; Plant defensin) P01545 Belongs to the thionin family THI1.1 Hordeum vulgare (Barley) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. No MICs found on DRAMP database Unknown 3082629##2850969 Eur J Biochem. 1986 Apr 1;156(1):131-135.##Gene. 1988 Oct 30;70(2):271-281. "Ponz F, Paz-Ares J, Hern??ndez-Lucas C, Garc??a-Olmedo F, Carbonero P.##Rodr??guez-Palenzuela P, Pintor-Toro JA, Carbonero P, Garc??a-Olmedo F." Cloning and nucleotide sequence of a cDNA encoding the precursor of the barley toxin alpha-hordothionin.##Nucleotide sequence and endosperm-specific expression of the structural gene for the toxin alpha-hordothionin in barley (Hordeum vulgare L.). DRAMP00970 KSCCRSTLGRNCYNLCRVRGAQKLCANACRCKLTSGLKCPSSFPK 45 Beta-hordothionin (beta-HT; Plant defensin) P21742 Belongs to the thionin family THI1.2 Hordeum vulgare (Barley) Antifungal Combine helix and strand structure Unknown 1WUW resolved by X-ray. Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. No MICs found on DRAMP database Unknown 15848162 FEBS Lett. 2005 Apr 25;579(11):2301-2306. "Johnson KA, Kim E, Teeter MM, Suh SW, Stec B." Crystal structure of alpha-hordothionin at 1.9 Angstrom resolution. DRAMP00971 QKTCCPSQSTRKEFEDCISEGNLQILCSAESGCRDTYVGYCPSGFPY 47 Probable thionin-2.3 (Plant defensin) "Q8VZK8, Q56XM5, Q6AWT2, Q9ZUL0" Belongs to the thionin family At2g15010 Arabidopsis thaliana (Mouse-ear cress) Cytotoxic Unknown Unknown Cytotoxic "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Problely contains three disulfide bonds 5-41; 5-33; 17-27." No MICs found on DRAMP database Unknown 10617197##14593172 Nature. 1999 Dec 16;402(6763):761-768.##Science. 2003 Oct 31;302(5646):842-846. "Lin X, Kaul S, Rounsley S, Shea TP, et al.##Yamada K, Lim J, Dale JM, Chen H, et al." Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.##Empirical analysis of transcriptional activity in the Arabidopsis genome. DRAMP00972 NICCPSIQARTFYNACLFAVGSPSSCIRNSSCLDISESTCPRGYTN 46 Probable thionin-2.4 (Plant defensin) Q9C8D6 Belongs to the thionin family At1g66100 Arabidopsis thaliana (Mouse-ear cress) Cytotoxic Unknown Unknown Cytotoxic "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains four disulfide bonds 3-40;4-32;16-26. " No MICs found on DRAMP database Unknown 11130712##14593172 Nature. 2000 Dec 14;408(6814):816-820.##Science. 2003 Oct 31;302(5646):842-846. "Theologis A, Ecker JR, Palm CJ, et al.##Yamada K, Lim J, Dale JM, et al." Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.##Empirical analysis of transcriptional activity in the Arabidopsis genome. DRAMP00973 KICCPSNQARNGYSVCRIRFSKGRCMQVSGCQNSDTCPRGWVN 43 Thionin-2.1 (Plant defensin) "Q42596, Q8LCH6, Q9C7S9" Belongs to the thionin family THI2.1 Arabidopsis thaliana (Mouse-ear cress) Cytotoxic Unknown Unknown Cytotoxic "Function: Seems to function as a defense factor. Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Tissue specificity: Detected in rosette leaves and at a very high " No MICs found on DRAMP database Unknown 11130712##14593172##8552715 Nature. 2000 Dec 14;408(6814):816-820.##Science. 2003 Oct 31;302(5646):842-846.##Plant Physiol. 1995 Nov;109(3):813-820. "Theologis A, Ecker JR, Palm CJ, et al.##Yamada K, Lim J, Dale JM, et al.##Epple P, Apel K, Bohlmann H." Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.##Empirical analysis of transcriptional activity in the Arabidopsis genome.##An Arabidopsis thaliana thionin gene is inducible via a signal transduction pathway different from that for pathogenesis-related proteins. DRAMP00974 KICCPTKDDRSVYFVCMLSVSSQFYCLLKSKCKNTSQTICPPGYTN 46 Thionin-2.2 (Plant defensin) "Q42597, Q8LEF0, Q9FIW2" Belongs to the thionin family THI2.2 Arabidopsis thaliana (Mouse-ear cress) Cytotoxic Bridge Unknown Cytotoxic "Function: Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. PTM: Contains three disulfide bonds 3-40;4-32;16-26. Tissue specificity: Low basal expression in seedlings. Also detected in rosette leaves." No MICs found on DRAMP database Unknown 8552715##10048488 Plant Physiol. 1995 Nov;109(3):813-820.##DNA Res. 1998 Dec 31;5(6):379-391. "Epple P, Apel K, Bohlmann H.##Asamizu E, Sato S, Kaneko T, Nakamura Y, Kotani H, Miyajima N, Tabata S." "An Arabidopsis thaliana thionin gene is inducible via a signal transduction pathway different from that for pathogenesis-related proteins.##Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence features of the regions of 1,081,958 bp covered by seventeen physically assigned P1 and TAC clones." DRAMP00975 RVCMKGSAGFKGLCMRDQNCAQVCLQEGWGGGNCDGVMRQCKCIRQC 47 SI alpha-2 (SIa2; Plant defensin) No entry found Unknown Unknown Sorghum bicolor (Seeds) Antifungal Bridge Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 1995329 FEBS Lett. 1991 Feb 11;279(1):101-104. "Bloch C Jr, Richardson M." A new family of small (5 kDa) protein inhibitors of insect alpha-amylases from seeds or sorghum (Sorghum bicolar (L) Moench) have sequence homologies with wheat gamma-purothionins. DRAMP00976 VGECVRGRCPSGMCCSQFGYCGKGPKYCG 29 Antimicrobial peptide 1 (AC-AMP1; Plant defensin) P27275 Unknown Unknown Amaranthus caudatus (Love-lies-bleeding) (Inca-wheat) "Antibacterial, Antifungal" Bridge Unknown Unknown "Function: Chitin-binding protein with a defensive Function: against numerous chitin containing fungal pathogens. It is also a potent inhibitor of Gram-positive bacteria. Miscellaneous: Its chitin-binding activity is strongly inhibited by divalent cations. PTM: Contains three disulfide bonds 4-15; 9-21; 14-28." "Gram-positive bacteria: Bacillus megaterium (IC50=40 ?g/ml), Sarcina lutea (IC50=250 ?g/ml).##Fungi: Alternaria brassicola (IC50=7 ?g/ml), Ascochyta pisi (IC50=8 ?g/ml), Botrytis cinera (IC50=10 ?g/ml), Colletotrichum lindemuthianum (IC50=8 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Trichoderma hamatum (IC50=7 ?g/ml), Verticillium dahliae (IC50=6 ?g/ml)." Chitin-binding 1567877##9176817 Biochemistry. 1992 May 5;31(17):4308-4314.##J Pept Res. 1997 Apr;49(4):336-340. "Broekaert W.F, Marien W, Terras F.R.G, de Bolle M.F.C, Proost P, van Damme J, Dillen L, Claeys M, Rees S.B, Vanderleyden J, Cammue B.P.A.##el Bouyoussfi M, Laus G, Verheyden P, Wyns L, Tourwe D, Van Binst G." Antimicrobial peptides from Amaranthus caudatus seeds with sequence homology to the cysteine/glycine-rich domain of chitin-binding proteins.##Location of the three disulfide bonds in an antimicrobial peptide from Amaranthus caudatus using mass spectrometry. DRAMP00977 VGECVRGRCPSGMCCSQFGYCGKGPKYCGR 30 Antimicrobial peptide 2 (AC-AMP2; Plant defensin) P27275 Unknown Unknown Amaranthus caudatus (Love-lies-bleeding) (Inca-wheat) "Antibacterial, Antifungal" Beta strand "The main structural element is an antiparallel beta-sheet from Met13 to Lys23 including a betaI-turn over Gln17-Phel8 with a beta bulge at Gly19. In addition, a beta'I turn over Arg6-Gly7, a beta'III turn over Ser11-Gly12 and a helical turn from Gly24 to Cys28 are identified." "1MMC, 1ZNT, 1ZUV, 1ZWU resolved by NMR." "Function: Chitin-binding protein with a defensive Function: against numerous chitin containing fungal pathogens. It is also a potent inhibitor of Gram-positive bacteria. Miscellaneous: Its chitin-binding activity is strongly inhibited by divalent cations. PTM: Contains three disulfide bonds 4-15; 9-21; 14-28." "Gram-positive bacteria: Bacillus megaterium (IC50=40 ?g/ml), Sarcina lutea (IC50=250 ?g/ml).##Fungi: Alternaria brassicola (IC50=7 ?g/ml), Ascochyta pisi (IC50=8 ?g/ml), Botrytis cinera (IC50=10 ?g/ml), Colletotrichum lindemuthianum (IC50=8 ?g/ml), Fusarium culmorum (IC50=2 ?g/ml), Trichoderma hamatum (IC50=7 ?g/ml), Verticillium dahliae (IC50=6 ?g/ml)." Chitin-binding 1567877##8627629##9176817 Biochemistry. 1992 May 5;31(17):4308-4314.##J Mol Biol. 1996 May 3;258(2):322-333.##J Pept Res. 1997 Apr;49(4):336-340. "Broekaert W.F, Marien W, Terras F.R.G, de Bolle M.F.C, Proost P, van Damme J, Dillen L, Claeys M, Rees S.B, Vanderleyden J, Cammue B.P.A.##Martins JC, Maes D, Loris R, Pepermans HA, Wyns L, Willem R, Verheyden P.##el Bouyoussfi M, Laus G, Verhey" "Antimicrobial peptides from Amaranthus caudatus seeds with sequence homology to the cysteine/glycine-rich domain of chitin-binding proteins.##H NMR study of the solution structure of Ac-AMP2, a sugar binding antimicrobial protein isolated from Amaranthus caudatus." DRAMP00978 QTCASRCPRPCNAGLCCSIYGYCGSGNAYCGAGNCRCQCRG 41 Antifungal peptide 1 (EAFP1; Plant defensin) P83596 Belongs to the hevein-like family Unknown Eucommia ulmoides (Hardy rubber tree) Antifungal Bridge Unknown Unknown "Function: Has antifungal activity. PTM: Contain five disulfide bonds 3-17; 7-37; 11-23; 16-30; 35-39, and Pyrrolidone carboxylic acid at position 1." "Fungi: Phytophthora infestans, Ascochyta lycopersici (IC50=155 ?g/ml), Verticillium dahliae, Gibberella zeae, Alternaria nicotianae, Fusarium moniliforme (IC50=56 ?g/ml), Fusarium oxysporum (IC50=46 ?g/ml) and Colletotrichum gossypii (IC50=35 ?g/ml). " Chitin-binding 12067732 FEBS Lett. 2002 Jun 19;521(1-3):87-90. "Huang R.-H, Xiang Y, Liu X.-Z, Zhang Y, Hu Z, Wang D.-C." Two novel antifungal peptides distinct with a five-disulfide motif from the bark of Eucommia ulmoides Oliv. DRAMP00979 QTCASRCPRPCNAGLCCSIYGYCGSGAAYCGAGNCRCQCRG 41 Antifungal peptide 2 (EAFP2; Plant defensin) P83597 Belongs to the hevein-like family Unknown Eucommia ulmoides (Hardy rubber tree) Antifungal Combine helix and strand structure "EAFP2 adopts a compact global fold composed of a 3(10) helix (Cys3-Arg6), an alpha-helix (Ala27-Cys31) and a three-stranded antiparallel beta-sheet (Cys16-Ser18, Cys23-Ser25, and Cys35-Cys37) and cross-linked by five disulfide bridges. The tertiary structure of EAFP2 shows a chitin-binding domain." 1P9G resolved by X-ray. "Function: Has antifungal activity. PTM: Contains five disulfide bonds 3-17; 7-37; 11-23; 16-30; 35-39, and Pyrrolidone carboxylic acid at position 1." "Fungi: Phytophthora infestans, Ascochyta lycopersici (IC50=109 ?g/ml), Verticillium dahliae, Gibberella zeae, Alternaria nicotianae, Fusarium moniliforme (IC50=18 ?g/ml), Fusarium oxysporum (IC50=94 ?g/ml) and Colletotrichum gossypii (IC50=56 ?g/ml)." Chitin-binding 12067732##15363789##15147184 FEBS Lett. 2002 Jun 19;521(1-3):87-90.##J Struct Biol. 2004 Oct;148(1):86-97.##Biochemistry. 2004 May 25;43(20):6005-6012. "Huang R.-H, Xiang Y, Liu X.-Z, Zhang Y, Hu Z, Wang D.-C.##Xiang Y, Huang RH, Liu XZ, Zhang Y, Wang DC.##Huang RH, Xiang Y, Tu GZ, Zhang Y, Wang DC." Two novel antifungal peptides distinct with a five-disulfide motif from the bark of Eucommia ulmoides Oliv.##Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Eucommia ulmoides Oliver at an atomic resolution.##Solution structure of Eucommia antifungal peptide: a novel structural model distinct with a five-disulfide motif. DRAMP00980 AQRCGDQARGAKCPNCLCCGKYGFCGSGDAYCGAGSCQSQCRGC 44 Antimicrobial peptide 1a (WAMP-1a; Plant defensin) P85966 Belongs to the hevein-like family Unknown Triticum kiharae (wheat) "Antibacterial, Antifungal" Combine helix and strand structure Unknown 2LB7 resolved by NMR. PTM: Contains five disulfide bonds 4-19; 13-25; 16-44; 18-32; 37-41. "Fungi: Bipolaris sorokiniana (IC50=5 ?g/ml), Botrytis cinerea (IC50=20 ?g/ml), Fusarium oxysporum (IC50=5 ?g/ml), Fusarium solani (IC50=5 ?g/ml), Fusarium verticillioides (IC50=30 ?g/ml), Neurospora crassa (IC50=10 ?g/ml);##Gram-positive bacterium: Clavibacter michiganensis (1.3cm inhibition for 2.5 ?g/50?l);##Gram-negative bacteria: Erwinia carotovora (1.1cm for 2.5 ?g/50?l), Pseudomonas syringae (0.9cm for 2.5 ?g/50?l)." Chitin-binding 19583772##16269343 FEBS J. 2009 Aug;276(15):4266-4275.##Peptides. 2005 Nov;26(11):2064-2073. "Odintsova TI, Vassilevski AA, Slavokhotova AA, Musolyamov AK, Finkina EI, Khadeeva NV, Rogozhin EA, Korostyleva TV, Pukhalsky VA, Grishin EV, Egorov TA.##Egorov TA, Odintsova TI, Pukhalsky VA, Grishin EV." A novel antifungal hevein-type peptide from Triticum kiharae seeds with a unique 10-cysteine motif.##Diversity of wheat anti-microbial peptides. DRAMP00981 AQRCGDQARGAKCPNCLCCGKYGFCGSGDAYCGAGSCQSQCRGCR 45 Antimicrobial peptide 1b (WAMP-1b; Plant defensin) P85966 Belongs to the hevein-like family Unknown Triticum kiharae (wheat) "Antibacterial, Antifungal" Unknown Unknown Unknown PTM: Contains five disulfide bonds 4-19; 13-25; 16-44; 18-32; 37-41. "Fungi: Bipolaris sorokiniana (IC50=5 ?g/ml), Botrytis cinerea (IC50=20 ?g/ml), Fusarium oxysporum (IC50=5 ?g/ml), F. solani (IC50=5 ?g/ml), F. verticillioides (IC50=30 ?g/ml), Neurospora crassa (IC50=10 ?g/ml);##Gram-positive bacterium: Clavibacter michiganensis (1.3cm inhibition for 2.5 ?g/50?l);##Gram-negative bacteria: Erwinia carotovora (1.1cm for 2.5 ?g/50?l), Pseudomonas syringae (0.9cm for 2.5 ?g/50?l)." Chitin-binding 19583772##16269343 FEBS J. 2009 Aug;276(15):4266-4275.##Peptides. 2005 Nov;26(11):2064-2073. "Odintsova TI, Vassilevski AA, Slavokhotova AA, Musolyamov AK, Finkina EI, Khadeeva NV, Rogozhin EA, Korostyleva TV, Pukhalsky VA, Grishin EV, Egorov TA.##Egorov TA, Odintsova TI, Pukhalsky VA, Grishin EV." A novel antifungal hevein-type peptide from Triticum kiharae seeds with a unique 10-cysteine motif.##Diversity of wheat anti-microbial peptides. DRAMP00982 AQCGAQGGGATCPGGLCCSQWGWCGSTPKYCGAGCQSNCK 40 Fa-AMP1 (Fagopyrum antimicrobial peptide 1; hevein-type; Plant defensin) No entry found Belongs to the hevein-like family Unknown Fagopyrum esculentum Moench (buckwheat) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Has antibacterial avtivity against Gram-positive bacteria and Gram-negative bacteria, also has antifungal activity." "Gram-positive bacteria: Clavibacter michiganensis (IC50=14 ?g/ml), Curtobacterium accumfaciens (IC50=13 ?g/ml);##Gram-negative bacteria: Erwinia carotovora (IC50=11 ?g/ml), Agrobacterium radiobacter (IC50=24 ?g/ml), Agrobacterium rhizogenes (IC50=20 ?g/ml).##Fungi: Fusarium oxysporum (IC50=19 ?g/ml), Geotrichum candidum (IC50=36 ?g/ml)." Unknown 12951494 Biosci Biotechnol Biochem. 2003 Aug;67(8):1636-1642. "Fujimura M, Minami Y, Watanabe K, Tadera K." "Purification, characterization, and sequencing of a novel type of antimicrobial peptides, Fa-AMP1 and Fa-AMP2, from seeds of buckwheat (Fagopyrum esculentum Moench.)." DRAMP00983 AQCGAQGGGATCPGGLCCSQWGWCGSTPKYCGAGCQSNCR 40 Fa-AMP2 (Fagopyrum antimicrobial peptide 2; hevein-type; Plant defensin) No entry found Belongs to the hevein-like family Unknown Fagopyrum esculentum Moench (buckwheat) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Has antibacterial avtivity against Gram-positive bacteria and Gram-negative bacteria, also has antifungal activity." "Gram-positive bacteria: Clavibacter michiganensis (IC50=17 ?g/ml), Curtobacterium accumfaciens (IC50=15 ?g/ml);##Gram-negative bacteria: Erwinia carotovora (IC50=15 ?g/ml), Agrobacterium radiobacter (IC50=17 ?g/ml), Agrobacterium rhizogenes (IC50=24 ?g/ml).##Fungi: Fusarium oxysporum (IC50=29 ?g/ml), Geotrichum candidum (IC50=25 ?g/ml)." Unknown 12951494 Biosci Biotechnol Biochem. 2003 Aug;67(8):1636-1642. "Fujimura M, Minami Y, Watanabe K, Tadera K." "Purification, characterization, and sequencing of a novel type of antimicrobial peptides, Fa-AMP1 and Fa-AMP2, from seeds of buckwheat (Fagopyrum esculentum Moench.)." DRAMP00984 AGECVQGRCPSGMCCSQFGYCGRGPKYCGR 30 Antimicrobial peptide Ar-AMP (Ar-AMP; hevin-like peptides; Plant defensin) Q5I2B2 Belongs to the hevein-like family Unknown Amaranthus retroflexus (Redroot amaranth) (Redroot pigweed) "Antibacterial, Antifungal" Bridge Unknown Unknown PTM: Contains three disulfide bonds 4-15; 9-21; 14-28. "Fungi: Botrytis cinerea, Fusarium culmorum, Helminthosporium sativum and Alternaria consortiale.##Gram-positive bacterium: Bacillus subtilis." Chitin-binding 16126239 Phytochemistry. 2005 Oct;66(20):2426-2431. "Lipkin A, Anisimova V, Nikonorova A, Babakov A, Krause E, Bienert M, Grishin E, Egorov T." An antimicrobial peptide Ar-AMP from amaranth (Amaranthus retroflexus L.) seeds. DRAMP00985 QQCGRQASGRLCGNRLCCSQWGYCGSTASYCGAGCQSQCRS 41 Pn-AMP1 (PnAMP1; Plant defensin) P81591 Belongs to the hevein-like family Unknown Ipomoea nil (Japanese morning glory) (Pharbitis nil) "Antibacterial, Antifungal" Bridge Unknown Unknown "Miscellaneous: Its antimicrobial activity is strongly inhibited by divalent cations. PTM: Contains four disulfide bonds 3-18; 12-24; 17-31; 35-39, and Pyrrolidone carboxylic acid at position 1." "Gram-positive Bacterium: Bacillus subtilis (IC50=38 ?g/ml).##Fungi (Medium A, Medium A+): Botrytis cinerea (IC50=16, 150 ?g/ml), Colletotrichum langenarium (IC50=10, >200 ?g/ml), Sclerotinia sclerotiorum (IC50=11, >200 ?g/ml), Fusarium oxysporum (IC50=10, >200 ?g/ml), Rhizoctonia solani (IC50=26, >200 ?g/ml), Phytophthora capsici (IC50=5, 130 ?g/ml), Phytophthora parasitica (IC50=3, 90 ?g/ml), Saccharomyces cerevisiae (IC50=14, >200 ?g/ml).##NOTE! Medium A+ = Medium A supplemented with 5 mM CaCl2." Chitin-binding 9507071 Biochim Biophys Acta. 1998 Jan 15;1382(1):80-90. "Koo JC, Lee SY, Chun HJ, Cheong YH, Choi JS, Kawabata S, Miyagi M, Tsunasawa S, Ha KS, Bae DW, Han CD, Lee BL, Cho MJ." Two hevein homologs isolated from the seed of Pharbitis nil L. exhibit potent antifungal activity. DRAMP00986 QQCGRQASGRLCGNRLCCSQWGYCGSTASYCGAGCQSQCR 40 Pn-AMP2 (PnAMP2; Plant defensin) P81591 Belongs to the hevein-like family Unknown Ipomoea nil (Japanese morning glory) (Pharbitis nil) Antifungal Bridge Unknown Unknown "Miscellaneous: Its antimicrobial activity is strongly inhibited by divalent cations. PTM: Contains four disulfide bonds 3-18; 12-24; 17-31; 35-39, and Pyrrolidone carboxylic acid at position 1." "Gram-positive bacterium: Bacillus subtilis (IC50=20 ?g/ml).##Fungi (Medium A, Medium A+): Botrytis cinerea (IC50=2, 95 ?g/ml), Colletotrichum langenarium (IC50=4, ND ?g/ml), Sclerotinia sclerotiorum (IC50=3, >200 ?g/ml), Fusarium oxysporum (IC50=2.5, >200 ?g/ml), Rhizoctonia solani (IC50=75, >200 ?g/ml), Phytophthora capsici (IC50=0.6, 150 ?g/ml), Phytophthora parasitica (IC50=2, >200 ?g/ml), Pythium spp. (IC50=2.5, ND ?g/ml), Saccharomyces cerevisiae (IC50=8, >200 ?g/ml).##NOTE! Medium A+ = Medium A supplemented with 5 mM CaCl2." Chitin-binding 9507071 Biochim Biophys Acta. 1998 Jan 15;1382(1):80-90. "Koo JC, Lee SY, Chun HJ, Cheong YH, Choi JS, Kawabata S, Miyagi M, Tsunasawa S, Ha KS, Bae DW, Han CD, Lee BL, Cho MJ." Two hevein homologs isolated from the seed of Pharbitis nil L. exhibit potent antifungal activity. DRAMP00987 QQCGRQAGNRRCANNLCCSQYGYCGRTNEYCCTSQGCQSQCRRCG 45 Ee-CBPb (Hevein-like antimicrobial peptide; Plants) No entry found Belongs to the hevein-like family Unknown Euonymus europaeus (European spindle tree) "Antibacterial, Antifungal" Unknown Unknown Unknown "Function: Ee-CBPb possesses a very strong antifungal activity. Besides fungi, Ee-CBP1 also inhibits the growth of Gram-positive bacteria but not that of Gram-negative bacteria and yeasts. PTM: Contains five disulfide bonds." "Fungi: Alternaria brassicicola (IC50=3 ?g/ml), Botrytis cinerea (IC50=1 ?g/ml), Fusarium culmorum (IC50=3 ?g/ml), Fusarium oxysporum f.sp.cubense (IC50=15 ?g/ml), Fusarium oxysporum f.sp. Matthiolae (IC50=5 ?g/ml), Mycosphaerella eumusae (IC50=6 ?g/ml), Neurospora crassa (IC50=2 ?g/ml), Phoma exigua (IC50=33 ?g/ml), Phytophthora cryptogea (IC50=25 ?g/ml), Pythium ultimum (IC50=33 ?g/ml), Rhizoctonia solani (IC50=25 ?g/ml).##Gram-positive bacteria: Bacillus megaterium (IC50=2 ?g/ml), Sarcina lutea (IC50=7 ?g/ml)." Chitin-binding 15048569##12387889 Planta. 2004 Jun;219(2):221-232.##FEBS Lett. 2002 Oct 23;530(1-3):181-185. "Van den Bergh KP, Roug?? P, Proost P, Coosemans J, Krouglova T, Engelborghs Y, Peumans WJ, Van Damme EJ.##Van den Bergh KP, Proost P, Van Damme J, Coosemans J, Van Damme EJ, Peumans WJ." Synergistic antifungal activity of two chitin-binding proteins from spindle tree (Euonymus europaeus L.).##Five disulfide bridges stabilize a hevein-type antimicrobial peptide from the bark of spindle tree (Euonymus europaeus L.). DRAMP00988 QQCGRQAGNRRCPNNLCCSQFGYCGRTNEYCCTGFGCQSNCRRCG 45 Ee-CBPl (Hevein-like antimicrobial peptide; Plants) No entry found Belongs to the hevein-like family Unknown Euonymus europaeus (European spindle tree) Antifungal Unknown Unknown Unknown "Function: Ee-CBP1 possesses a very strong antifungal activity. PTM: Contains Disulfide bond." "Fungi: Alternaria brassicicola (IC50=0.6 ?M), Botrytis cinerea (IC50=0.2 ?M), Fusarium culmorum (IC50=0.6 ?M), Fusarium oxysporum f. sp. cubense (IC50=3 ?M), Fusarium oxysporum f. sp. matthiolae (IC50=1 ?M), Mycosphaerella eumusae (IC50=1.2 ?M), Neurospora crassa (IC50=0.4 ?M), Phoma exigua (IC50=6.6 ?M),Phytophthora cryptogea (IC50=5 ?M), Pythium ultimum (IC50=6.6 ?M), Rhizoctonia solani (IC50=5 ?M), Trichoderma hamatum (IC50=20 ?M)." Chitin-binding 15048569 Planta. 2004 Jun;219(2):221-232. "Van den Bergh KP, Roug?? P, Proost P, Coosemans J, Krouglova T, Engelborghs Y, Peumans WJ, Van Damme EJ." Synergistic antifungal activity of two chitin-binding proteins from spindle tree (Euonymus europaeus L.). DRAMP00989 EQCGRQAGGKLCPNNLCCSQWGWCGSTDEYCSPDHNCQSNCKD 43 Hevein (Hev b 6; Plants) P02877 Belongs to the hevein-like family HEV1 Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis) Antifungal Combine helix and strand structure The first high-resolution solution-state structure of a member of the toxin-agglutinin folding motif with the WGA disulfide linkage is presented. "1HEV resolved by NMR.##1Q9B, 1WKX resolved by X-ray." "Function: N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin. Can inhibit fungal growth. PTM: Proteolytically processed to yield the two chains of the mature protein, and it Contains four disulfide bonds 3-18; 12-24; 17-31; 37-41. Allergenic properties: Causes an allergic reaction in human." No MICs found on DRAMP database Chitin-binding 2217194##8431421 Proc Natl Acad Sci U S A. 1990 Oct;87(19):7633-7637.##Biochemistry. 1993 Feb 16;32(6):1407-1422. "Broekaert I, Lee HI, Kush A, Chua NH, Raikhel N.##Andersen NH, Cao B, Rodr赤guez-Romero A, Arreguin B." Wound-induced accumulation of mRNA containing a hevein sequence in laticifers of rubber tree (Hevea brasiliensis).##Hevein: NMR assignment and assessment of solution-state folding for the agglutinin-toxin motif. DRAMP00990 KICERASGTWKGICIHSNDCNNQCVKWENAGSGSCHYQFPNYMCFCYFDC 50 Sm-AMP-D1 (Plant defensin) No entry found Unknown Unknown Stellaria media L (Common chickweed seeds) Antifungal Unknown Unknown Unknown Function: Sm-AMP-D defensins displays strong antifungal activity against important plant pathogens being active at very low concentrations (IC50=1 M). "Fungi: Fusarium oxysporum 16/10 (IC50=0.5 ?M), Botrytis cinerea SGR-1 (IC50=0.35 ?M), Bipolaris sorokiniana 6/10 (IC50=0.52 ?M), Fusarium graminearum VKM F-1668 (IC50=0.52 ?M), Fusarium avenaceum VKM F-2303 (IC50=1 ?M), Phoma betae VKM F-2532 (IC50=0.52 ?M), Pythium debaryanum VKMF-1505 (IC50=1 ?M)." Unknown 21056078 Biochimie. 2011 Mar;93(3):450-456. "Slavokhotova AA, Odintsova TI, Rogozhin EA, Musolyamov AK, Andreev YA, Grishin EV, Egorov TA." "Isolation, molecular cloning and antimicrobial activity of novel defensins from common chickweed (Stellaria media L.) seeds." DRAMP00991 EQCGRQAGGKLCPNNLCCSQYGWCGSSDDYCSPSKNCQSNCKGGG 45 Pseudo-hevein (Minor hevein; hevein-like peptides; Plants) P80359 Unknown Unknown Hevea brasiliensis (Para rubber tree) Antifungal Bridge Unknown Unknown "Function: N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin. Can inhibit fungal growth. PTM: Problely Contains four disulfide bonds 3-18; 12-24; 17-31; 37-41." No MICs found on DRAMP database Chitin-binding 7947977 Biochim Biophys Acta. 1994 Nov 16;1209(1):144-148. "Soedjanaatmadja UM, Hofsteenge J, Jeronimus-Stratingh CM, Bruins AP, Beintema JJ." Demonstration by mass spectrometry that pseudo-hevein and hevein have ragged C-terminal sequences. DRAMP00992 KICERASGTWKGICIHSNDCNNQCVKWENAGSGSCHYQFPNYMCFCYFNC 50 Sm-AMP-D2 (Plant defensin) No entry found Unknown Unknown Stellaria media L (Common chickweed seeds) Antifungal Unknown Unknown Unknown Function: Sm-AMP-D defensins displays strong antifungal activity against important plant pathogens being active at very low concentrations (IC50=1 M). "Fungi: Fusarium oxysporum 16/10 (IC50=0.5 ?M), Botrytis cinerea SGR-1 (IC50=0.35 ?M), Bipolaris sorokiniana 6/10 (IC50=0.52 ?M), Fusarium graminearum VKM F-1668 (IC50=0.52 ?M), Fusarium avenaceum VKM F-2303 (IC50=1 ?M), Phoma betae VKM F-2532 (IC50=0.52 ?M), Pythium debaryanum VKMF-1505 (IC50=1 ?M)." Unknown 21056078 Biochimie. 2011 Mar;93(3):450-456. "Slavokhotova AA, Odintsova TI, Rogozhin EA, Musolyamov AK, Andreev YA, Grishin EV, Egorov TA." "Isolation, molecular cloning and antimicrobial activity of novel defensins from common chickweed (Stellaria media L.) seeds." DRAMP00993 QAGGQTCPGGICCSQWGYCGTTADYCSPNNNCQSNCWASG 40 WjAMP-1 (C-terminal domain of hevein; Plant defensin) No entry found Unknown WjAMP-1 Wasabia japonica L. (Wasabi plant) (Wasabia japonica) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: WjAMP-1 showed antimicrobial activity against both fungi and bacteria. "Gram-negative bacteria: Escherichia coli (IC50=27.5 ?g/ml), Pseudomonas cichorii (IC50=13.8 ?g/ml), Pseudomonas glumae (IC50=20 ?g/ml), Pseudomonas plantarii (IC50=22.5 ?g/ml), Agrobacterium tumefaciens (IC50=12.5 ?g/ml).##Fungi: Alternaria alternata (IC50=5.8 ?g/ml), Botrytis cinerea (IC50=15 ?g/ml), Fusarium solani (IC50=8.4 ?g/ml), Magnaporte grisea (IC50=80 ?g/ml)." Chitin-binding 12668776 Plant Cell Physiol. 2003 Mar;44(3):296-303. "Kiba A, Saitoh H, Nishihara M, Omiya K, Yamamura S." C-terminal domain of a hevein-like protein from Wasabia japonica has potent antimicrobial activity. DRAMP00994 QWGRRCCGWGPGRRYCVRWC 20 IB-AMP1 (IBAMP1; Basic peptide AMP1; Plants) O24006 Unknown AMP Impatiens balsamina (Balsam) "Antibacterial, Antifungal" Bridge Unknown Unknown "Developmental stage: Highly expressed in dry mature seed and by the stages 2-5 of developing seed. The peptide IB-AMP1 is also detected at early stages of germination (24 hours and 48 hours postgermination). PTM: Contains two disulfide bonds C6-C16; C7-C2" "Gram-positive bacteria: Bacillus subtilis (IC50=10 ?g/ml), Micrococcus luteus (IC50=10 ?g/ml), Staphylococcus aureus (IC50=30 ?g/ml), Streptococcus faecalis (IC50=6 ?g/ml).##Fungi: Alternaria longipes (IC50=3 ?g/ml), Botrytis cinerea (IC50=12 ?g/ml), Cladosporium sphaerospermum (IC50=1 ?g/ml), Fusarium culmorum (IC50=1 ?g/ml), Penicillium digitatum (IC50=3 ?g/ml), Trichoderma viride (IC50=6 ?g/ml), Verticillium alboatrum (IC50=3 ?g/ml)." Unknown 9305910##9454588 J Biol Chem. 1997 Sep 26;272(39):24480-24487.##Biochemistry. 1998 Jan 27;37(4):983-990. "Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF.##Patel SU, Osborn R, Rees S, Thornton JM." A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein.##Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1). DRAMP00995 QYGRRCCNWGPGRRYCKRWC 20 IB-AMP2 (IBAMP2; Basic peptide AMP2; Plants) O24006 Unknown Unknown Impatiens balsamina (Balsam) Antifungal Bridge Unknown Unknown "Developmental stage: Highly expressed in dry mature seed and by the stages 2-5 of developing seed. PTM: Contains two disulfide bonds C6-C16; C7-C20 and Pyrrolidone carboxylic acid at position 1 (Probable)." "Fungi: Alternaria longipes (IC50=12 ?g/ml), Botrytis cinerea (IC50=25 ?g/ml), Cladosporium sphaerospermum (IC50=6 ?g/ml), Fusarium culmorum (IC50=6 ?g/ml), Penicillium digitatum (IC50=6 ?g/ml), Trichoderma viride (IC50=12 ?g/ml), Verticillium alboatrum (IC50=12 ?g/ml)." Unknown 9305910 J Biol Chem. 1997 Sep 26;272(39):24480-24487. "Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF." A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein. DRAMP00996 QYRHRCCAWGPGRKYCKRWC 20 IB-AMP3 (IBAMP3; Basic peptide AMP3; Plants) O24006 Unknown Unknown Impatiens balsamina (Balsam) Antifungal Bridge Unknown Unknown "Developmental stage: Highly expressed in dry mature seed and by the stages 2-5 of developing seed. PTM: Contains two disulfide bonds C6-C16; C7-C20 and Pyrrolidone carboxylic acid at position 1 (Probable)." "Fungi: Alternaria longipes (IC50=6 ?g/ml), Botrytis cinerea (IC50=6 ?g/ml), Cladosporium sphaerospermum (IC50=3 ?g/ml), Fusarium culmorum (IC50=6 ?g/ml), Penicillium digitatum (IC50=3 ?g/ml), Trichoderma viride (IC50=12 ?g/ml), Verticillium alboatrum (IC50=6 ?g/ml)." Unknown 9305910 J Biol Chem. 1997 Sep 26;272(39):24480-24487. "Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF." A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein. DRAMP00997 QWGRRCCGWGPGRRYCRRWC 20 IB-AMP4 (IBAMP4; Basic peptide AMP4; Plants) O24006 Unknown Unknown Impatiens balsamina (Balsam) "Antibacterial, Antifungal" Bridge Unknown Unknown Developmental stage: Highly expressed in dry mature seed and by the stages 2-5 of developing seed. PTM: Contains two disulfide bonds C6-C16; C7-C20 and Pyrrolidone carboxylic acid at position 1 (Probable). Note: Peptide IB-AMP4 has a higher antifungal act "Gram-positive bacteria: Bacillus subtilis (IC50=5 ?g/ml), Micrococcus luteus (IC50=5 ?g/ml), Staphylococcus aureus (IC50=20 ?g/ml), Streptococcus faecalis (IC50=5 ?g/ml);##Gram-negative bacteria: Xanthomonas campestris (IC50=6 ?g/ml), Xanthomonas oryzae (IC50=15 ?g/ml).##Fungi: Alternaria longipes (IC50=3 ?g/ml), Botrytis cinerea (IC50=6 ?g/ml), Cladosporium sphaerospermum (IC50=1 ?g/ml), Fusarium culmorum (IC50=1 ?g/ml), Penicillium digitatum (IC50=3 ?g/ml), Trichoderma viride (IC50=6 ?g/ml), Verticillium alboatrum (IC50=6 ?g/ml)." Unknown 9305910##9454588 J Biol Chem. 1997 Sep 26;272(39):24480-24487.##Biochemistry. 1998 Jan 27;37(4):983-990. "Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF.##Patel SU, Osborn R, Rees S, Thornton JM." A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein.##Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1). DRAMP00998 RSGRGECRRQCLRRHEGQPWETQECMRRCRRRG 33 Antimicrobial peptide MBP-1 (Maize Basic Peptide 1; Plant defensin) P28794 Unknown Unknown Zea mays (Maize) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Inhibitor of both bacterial and fungal growth in vitro. "Gram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Corynebacterium nebraskense ssp.##Fungi: Fusarium graminearum, Fusarium moniliforme, Aspergillus flavus, Alonina longipes, Sclerotinia sclerotiorum, Sclerotinia trifoliorum. " Unknown 1527010 J. Biol. Chem. 1992; 267:18814-18820 "Duvick JP, Rood T, Rao AG, Marshak DR.1992" Purification and characterization of a novel antimicrobial peptide from maize (Zea mays L.) kernels. DRAMP00999 GFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY 40 Plectasin (fungal defensin) Q53I06 Unknown DEF Pseudoplectania nigrella (Ebony cup) "Antibacterial, Antifungal" Combine helix and strand structure Unknown 1ZFU resolved by NMR. "Function: Recombinant peptide is especially active against Streptococcus pneumoniae, including strains resistant to conventional antibiotics. Plectasin showes extremely low toxicity in mice, and cured them of experimental peritonitis and pneumonia caused by S. pneumoniae as efficaciously as vancomycin and penicillin." Gram-positive bacterium: Streptococcus pneumoniae. Lipid II 16222292 Nature. 2005 Oct 13;437(7061):975-780. "Mygind PH, Fischer RL, Schnorr KM, Hansen MT, S??nksen CP, Ludvigsen S, Ravent??s D, Buskov S, Christensen B, De Maria L, Taboureau O, Yaver D, Elvig-J??rgensen SG, S??rensen MV, Christensen BE, Kjaerulff S, Frimodt-Moller N, Lehrer RI, Zasloff M, Kristensen " Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus. DRAMP01000 YQCGQGG 7 Ascalin (Plants) P84071 Unknown Unknown Allium cepa var. aggregatum (shallot) "Antifungal, Antiviral" Unknown Unknown Unknown "Function: Has antifungal activity against Botrytis cinerea. Inhibits HIV-1 reverse transcriptase. Miscellaneous: Inhibits HIV-1 reverse transcriptase with an IC50 of 10 ?M." "Botrytis cinerea, HIV-1 reverse transcriptase (IC50=10 ?M)." Unknown 12126728 Peptides. 2002 Jun;23(6):1025-1029. "Wang HX, Ng TB." "Ascalin, a new anti-fungal peptide with human immunodeficiency virus type 1 reverse transcriptase-inhibiting activity from shallot bulbs." DRAMP01001 GVGYKVVVTTTAAADDDDVV 20 Arietin (Plants) P83988 Unknown Unknown Cicer arietinum (chickpea) Antifungal Unknown Unknown Unknown Function: Has antifungal activity. Inhibits cell-free translation in rabbit reticulocyte lysate system. Does not have mitogenic and anti-HIV-1 reverse transcriptase activities. "Fungi: Botrytis cinerea, Fusarium oxysporum, Mycosphaerella arachidicola." Unknown 12084511 Peptides. 2002 May;23(5):817-822. "Ye XY, Ng TB, Rao PF." "Cicerin and arietin, novel chickpea peptides with different antifungal potencies." DRAMP01002 RDWERREFERRQNELRREQEQRREELL 27 Alpha-benincasin (Plants) P83960 Unknown Unknown Benincasa hispida Antifungal Unknown Unknown Unknown "Function: Has weak antifungal activity toward C. comatus and P. piricola but not toward M. arachidicola. Inhibits cell-free translation in rabbit reticulocyte lysate system. Miscellaneous: IC50 of 20 pM in rabbit reticulocyte." "Fungi: Coprinus comatus, Pseudocercospora piricola." Unknown 12576080 Peptides. 2003 Jan;24(1):11-16. "Ng TB, Parkash A, Tso WW." "Purification and characterization of alpha- and beta-benincasins, arginine/glutamate-rich peptides with translation-inhibiting activity from wax gourd seeds." DRAMP01003 KTCENLADDY 10 Gymnin (Plants) P84200 Unknown Unknown Gymnocladus chinensis "Antifungal, Antiviral" Unknown Unknown Unknown Function: Exerts antifungal activity. Has weak mitogenic activity against murine splenocytes. Displays antiproliferative activity on a human hepatoma cell line and mouse leukemia cell lines. Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase. "Fungi: Fusarium oxysporum (IC50=2 ?M), Mycosphaerella arachidicola (IC50=10 ?M)." Unknown 14499273 Peptides. 2003 Jul;24(7):963-968. "Wong JH, Ng TB." "Gymnin, a potent defensin-like antifungal peptide from the Yunnan bean (Gymnocladus chinensis Baill)." DRAMP01005 VKSTGRADDDLAVKTKYLPP 20 Cicerarin (Plant defensin) P83986 Unknown Unknown Cicer arietinum (chickpea) "Antifungal, Antiviral" Unknown Unknown Unknown Function: Has antifungal activity. Also inhibits HIV-1 reverse transcriptase. "Fungi: Botrytis cinerea (IC50=20.6 ?M), Mycosphaerella arachidicola (IC50=15.3 ?M), Pseudocercospora piricola (IC50=8.2 ?M).##Virus: HIV-1 RT (IC50=87.5 ?M)" Unknown 12895650 Peptides. 2003 May;24(5):659-663. "Chu KT, Liu KH, Ng TB." "Cicerarin, a novel antifungal peptide from the green chickpea." DRAMP01006 ARCENFADSYRQPPISSSQT 20 Cicerin (Plant defensin) P83987 Unknown Unknown Cicer arietinum (chickpea) Antifungal Unknown Unknown Unknown Function: Has antifungal activity. Inhibits cell-free translation in rabbit reticulocyte lysate system. "Fungi: Mycosphaerella arachidicola, Fusarium oxysporum, Botrytis cinerea (IC50=12 ?M)." Unknown 12084511 Peptides. 2003 May;24(5):665-669. "Cai YD, Liu XJ, Li YX, Xu XB, Chou KC." "Cicerin and arietin, novel chickpea peptides with different antifungal potencies." DRAMP01007 MTCGQVQGNLAQCIGFLQKGGVVPPSCCTGVKNILNSSRTTADRRAVCSCLKAAAGAVRGINPNNAEALPGKCGVNIPYKISTSTNCNSIN 91 Non-specific lipid transfer peptide (LTP 1; nsLTP; Plants) P83434 Unknown Unknown Vigna radiata var. radiata (Mung bean) (Phaseolus aureus) "Antibacterial, Antifungal" Alpha helix (4 helices; 46 residues) The global fold of mung bean nsLTP1 is similar to those of the monocotyledonous nsLTP1 structures and consists of four alpha-helices stabilized by four disulfide bonds. 1SIY resolved by NMR. "Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. PTM: Contains four disulfide bonds 3-50; 13-27; 28-73; 48-87." "Fungi: Fusarium solani, Fusarium oxysporum, Pythium aphanidermatum, Sclerotium rolfsii.##Gram-positive Bacterium: Staphylococcus aureus." Lipid-binding 15350690##15823028 Peptides. 2004 Aug;25(8):1235-1242.##Biochemistry. 2005 Apr 19;44(15):5703-5712. "Wang SY, Wu JH, Ng TB, Ye XY, Rao PF.##Lin KF, Liu YN, Hsu ST, Samuel D, Cheng CS, Bonvin AM, Lyu PC." A non-specific lipid transfer protein with antifungal and antibacterial activities from the mung bean.## Characterization and structural analyses of nonspecific lipid transfer protein 1 from mung bean. DRAMP01008 SNDIYFNFQR 10 Antifungal lectin PVAP (Plant defensin) P84869 Unknown Unknown Phaseolus vulgaris (Kidney bean) Antifungal Unknown Unknown Unknown "Function: Has hemagglutinating activity towards rabbit erythrocytes. Has antiproliferative activity towards L1210 tumor cell line with an IC50 of 3.6 ?M. Miscellaneous: Antifungal, antiproliferative and hemagglutinating activity is abolished by incubatio" Fungi: Mycophaerella arachidicola (IC50=9.8 ?M). Unknown 16026901 Peptides. 2005 Dec;26(12):2397-2403. "Xia L, Ng T.B." An antifungal protein from flageolet beans DRAMP01009 DDFLCAGGCL 10 Alliumin (Plants) P84796 Unknown Unknown Allium sativum (Garlic) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Has antifungal activity against M.arachidicola with an IC50 of 1.3 ?M. Has antibacterial activity against the Gram-negative bacteria P. fluorescens. Has antiproliferative activity towards L1210 leukemia cells with an IC50 of 8.33 ?M. Fungi: Mycosphaerella arachidicola (IC50=1.3 ?M).##Gram-negative bacterium: Pseudomonas fluorescens. Unknown 15629528 Peptides. 2005 Feb;26(2):177-183. "Xia L, Ng TB." "Isolation of alliumin, a novel protein with antimicrobial and antiproliferative activities from multiple-cloved garlic bulbs." DRAMP01010 KTCENLADTFRGPCFATSNC 20 Lunatusin (Plants) No entry found Unknown Unknown Phaseolus lunatus L.(Chinese lima bean) "Antibacterial, Antifungal, Antiviral" Unknown Unknown Unknown Function: It also inhibited proliferation in the breast cancer cell line MCF-7. Lunatusin reduced the activity of HIV-1 reverse transcriptase and it also inhibited translation in a cell-free rabbit reticulocyte lysate system. Its anti-fungal activity was "Fungi: Fusarium oxysporum, Mycosphaerella arachidicola and Botrytis cinerea.##Gram-positive bacteria: Bacillus megaterium, Bacillus subtilis;##Gram-negative bacteria: Proteus vulgaris, Mycobacterium phlei." Unknown 16269344 Peptides. 2005 Nov;26(11):2086-2092. "Wong JH, Ng TB." "Lunatusin, a trypsin-stable antimicrobial peptide from lima beans (Phaseolus lunatus L.)." DRAMP01011 KTCENLADTFRGPCFATSNCDDHCKNKEHLLSGRCRDDFRCWCTRNC 47 White cloud bean defensin (Plant defensin) No entry found Unknown Unknown Phaseolus vulgaris cv. white cloud bean? "Antibacterial, Antifungal" Bridge Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 16687191 Peptides. 2006 Sep;27(9):2075-2081. "Wong JH, Zhang XQ, Wang HX, Ng TB." A mitogenic defensin from white cloud beans (Phaseolus vulgaris). DRAMP01013 KTCENLADTYKGPCFTTGSCD 21 PvD1 (P. vulgaris defensin 1; Plants) F8QXP9 Unknown Unknown Phaseolus vulgaris (Seeds) Antifungal Bridge Unknown Unknown "Its activity involves membrane permeabilization, inhibition of medium acifification, and induction of ROS in fungi cells (Curr Microbiol. 2010 Dec 19. 62: 1209-1217). " "Fungi: Candida albicans, C. parapsilosis, Candida tropicalis, Candida guilliermondii, K. marxiannus, Saccharomyces cerevisiae, Fusarium oxysporum, F. solani, F. lateritium and R. solani." Unknown 18786582 Peptides. 2008 Dec;29(12):2090-2100. "Games PD, Dos Santos IS, Mello EO, Diz MS, Carvalho AO, de Souza-Filho GA, Da Cunha M, Vasconcelos IM, Ferreira Bdos S, Gomes VM." "Isolation, characterization and cloning of a cDNA encoding a new antifungal defensin from Phaseolus vulgaris L. seeds." DRAMP01014 RTCMIKKEGWGKCLIDTTCAHSCKNRGYIGGNCKGMTRTCYCLVNC 46 VrD1 (V.radiata defensin 1; Plants) No entry found Unknown Unknown Vigna radiata Antifungal Combine helix and strand structure Unknown 1TI5 resolved by NMR. No comments found on DRAMP database "Fungi: Fusarium oxysporum, Pyricularia oryza, Rhizoctonia solani, Trichophyton rubrum, bruchid larva." Unknown 15080630 J Agric Food Chem 2004; 52: 2256-2261. Chen JJ et al Chen CS. Cloning and functional expression of a mungbean defensin VrD1 in Pichia pastoris. DRAMP01015 RTCMKKEGWGKCLIDTTCAHSCKNRGYIGGNCKGMTRTCYCLVNC 45 VaD1 (Plant defensin) No entry found Unknown Unknown Vigna angularis Kao Hsiung No.6 (Seeds) "Antibacterial, Antifungal" Unknown Unknown Unknown No comments found on DRAMP database "Fungi: Fusarium oxysporum, Fusarium oxysporum f. sp. Pisi.##Gram-positive bacterium: Staphylococcus epidermidis;##Gram-negative bacterium: Salmonella typhimurium." Unknown 15713009 J Agric Food Chem 2005; 53: 982-988. "Chen G.-H. et al. Chen, C.-S." Cloning and characterization of a plant defensin VaD1 from Azuki Bean. DRAMP01019 KTCENLANTYRGPCFTTGSCDDHCKNKEHLRSGRCRDDFRCWCTRNC 47 VrD2 (Vigna radiata defensin 2; plant defensin) No entry found Unknown Unknown Vigna radiata "Antibacterial, Antifungal" Combine helix and strand structure Unknown 2GL1 resolved by NMR. No comments found on DRAMP database No MICs found on DRAMP database Unknown PubMed ID is not available Proteins 2007; 68: 530-540. "Lin KF, Lee TR, Tsai PH, Hsu MP, Chen CS, Lyu PC." NMR solution structure of Vigna radiata Defensin 2 (VrD2). DRAMP01020 RVCMKGSQHHSFPCISDRLCSNECVKEEGGWTAGYCHLRYCRCQKAC 47 SIalpha1 (Plant defensin) No entry found Unknown Unknown Sorghum bicolor Antibacterial Combine helix and strand structure Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 9715910 Proteins. 1998 Aug 15;32(3):334-349. "Bloch C Jr, Patel SU, Baud F, Zvelebil MJ, Carr MD, Sadler PJ, Thornton JM." 1H NMR structure of an antifungal gamma-thionin protein SIalpha1: similarity to scorpion toxins. DRAMP01021 AQKCGEQGRGAKCPNCLCCGRYGFCGSTPDYCGVGCQSQCRGC 43 Antimicrobial peptide 1a (LAMP-1a; Plant defensin) P86521 Unknown Unknown Leymus arenarius (Lyme grass) (Elymus arenarius) Antimicrobial Bridge Unknown Unknown PTM: Contains five disulfide bonds 4-19; 13-25; 16-43; 18-32; 36-40. No MICs found on DRAMP database Chitin-binding PubMed ID is not available Submitted (APR-2010) to UniProtKB Odintsova TI. unknow DRAMP01022 KGAPCAKKPCCGPLGHYKVDCSTIPDYPCCSKYGFCGSGPQYCG 44 Cy-AMP1 (Plant defensin) No entry found Unknown Unknown Cycas revoluta (cycad seeds) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Cy-AMP1 has antimicrobial activity against various plant-pathogenic fungi and bacteria. "Gram-positive bacteria: Clavibacterium michiganensis (IC50=7.3 ?g/ml), Curtobacterium ???accumfaciens (IC50=8.9 ?g/ml);##Gram-negative bacteria: Agrobacterium radiobacter (IC50=8.3 ?g/ml), Agrobacterium rhizogenes (IC50=8.5 ?g/ml), Erwinia carobora (IC50=8.0 ?g/ml).##Fungi: Fusarium oxysporum (IC50=6.0 ?g/ml), Geotrichum candidum (IC50=7.4 ?g/ml)." Lipid-binding 18778743 Peptides. 2008 Dec;29(12):2110-2117. "Yokoyama S, Kato K, Koba A, Minami Y, Watanabe K, Yagi F." "Purification, characterization, and sequencing of antimicrobial peptides, Cy-AMP1, Cy-AMP2, and Cy-AMP3, from the Cycad (Cycas revoluta) seeds." DRAMP01023 KGGPCAKKPCCGPLGHYKVDCSTIPDYPCCSKYGFCGSGPQYCG 44 Cy-AMP2 (Plant defensin) No entry found Unknown Unknown Cycas revoluta (cycad seeds) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Cy-AMP2 has antimicrobial activity against various plant-pathogenic fungi and bacteria. "Gram-positive bacteria: Clavibacterium michiganensis (IC50=7.6 ?g/ml), Curtobacterium ???accumfaciens (IC50=8.3 ?g/ml);##Gram-negative bacteria: Agrobacterium radiobacter (IC50=7.8 ?g/ml), Agrobacterium rhizogenes (IC50=8.2 ?g/ml), Erwinia carobora (IC50=8.1 ?g/ml).##Fungi: Fusarium oxysporum (IC50=7.1 ?g/ml), Geotrichum candidum (IC50=7.0 ?g/ml)." Lipid-binding 18778743 Peptides. 2008 Dec;29(12):2110-2117. "Yokoyama S, Kato K, Koba A, Minami Y, Watanabe K, Yagi F." "Purification, characterization, and sequencing of antimicrobial peptides, Cy-AMP1, Cy-AMP2, and Cy-AMP3, from the Cycad (Cycas revoluta) seeds." DRAMP01024 AVTCNTVVSSLAPCVPFFAGSAAQPTAACCNGVRSLNSAARTTPDRRTACNCIKSSASSIGLNYNKAAKLPSRCTVNVTVPISPSVNCAT 90 Cy-AMP3 (Plant defensin) No entry found Unknown Unknown Cycas revoluta (cycad seeds) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Cy-AMP3 has weak antimicrobial activity against various plant-pathogenic fungi and bacteria. "Gram-positive bacteria: Clavibacterium michiganensis (IC50=235 ?g/ml), Curtobacterium ???accumfaciens (IC50=195 ?g/ml);##Gram-negative bacteria: Agrobacterium radiobacter (IC50=260 ?g/ml), Agrobacterium rhizogenes (IC50=235 ?g/ml), Erwinia carobora (IC50=230 ?g/ml).##Fungi: Fusarium oxysporum (IC50=250 ?g/ml), Geotrichum candidum (IC50=200 ?g/ml)." Lipid-binding 18778743 Peptides. 2008 Dec;29(12):2110-2117. "Yokoyama S, Kato K, Koba A, Minami Y, Watanabe K, Yagi F." "Purification, characterization, and sequencing of antimicrobial peptides, Cy-AMP1, Cy-AMP2, and Cy-AMP3, from the Cycad (Cycas revoluta) seeds." DRAMP01025 ESEFDRQEYEECKRQCMQLETSGQMRRCVSQCDKRFEEDIDWSKYDNQD 49 Vicilin-like Antimicrobial peptide 2a (MiAMP2a; Plant defensin) "Q9SPL4, Q9SPL5, Q9SPL3" Belongs to the vicilin-like family AMP2-2 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown No comments found on DRAMP database "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml).##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01026 DPQTDCQQCQRRCRQQESGPRQQQYCQRRCKEICEEEEEYN 41 Vicilin-like Antimicrobial peptide 2b (MiAMP2b; Plant defensin) "Q9SPL4, Q9SPL5, Q9SPL3" Belongs to the vicilin-like family AMP2-2 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown No comments found on DRAMP database "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01027 RQRDPQQQYEQCQKHCQRRETEPRHMQTCQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEEDN 68 MiAMP2c (Gln- and Glu-rich; Plant defensin) No entry found Belongs to the vicilin-like family Unknown Macadamia integrifolia (Macadamia nut) Antifungal Rich Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01028 RQRDPQQQYEQCQERCQRHETEPRHMQTCQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEED 67 Vicilin-like Antimicrobial peptide 2c-3 (MiAMP2c-3; Plant defensin) Q9SPL4 Belongs to the vicilin-like family AMP2-2 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01029 RQRDPQQQYEQCQERCQRHETEPRHMQTCQQRCERRYEKEKRKQQKR 47 Vicilin-like Antimicrobial peptide 2c-2 (MiAMP2c-2; Plant defensin) Q9SPL4 Belongs to the vicilin-like family AMP2-2 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01030 RQRDPQQQYEQCQERCQRHETEPRHMQTCQQRCERRYEKEKRKQQ 45 Vicilin-like Antimicrobial peptide 2c-1 (MiAMP2c-1; Plant defensin) Q9SPL4 Belongs to the vicilin-like family AMP2-2 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01031 KRDPQQREYEDCRRRCEQQEPRQQYQCQRRCREQQ 35 Vicilin-like Antimicrobial peptide 2d (MiAMP2d; Plant defensin)fens Q9SPL4 Belongs to the vicilin-like family AMP2-2 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2d has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01032 DPQTECQQCQRRCRQQESDPRQQQYCQRRCKEICEEEEEYN 41 Vicilin-like Antimicrobial peptide 2b (MiAMP2b; Plant defensin)fens Q9SPL3 Belongs to the vicilin-like family AMP2-3 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2b has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01033 RQRDPQQQYEQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEGD 67 Vicilin-like Antimicrobial peptide 2c-3 (MiAMP2c-3; Plant defensin) Q9SPL3 Belongs to the vicilin-like family AMP2-3 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01034 RQRDPQQQYEQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQKR 47 Vicilin-like Antimicrobial peptide 2c-2 (MiAMP2c-2; Plant defensin) Q9SPL3 Belongs to the vicilin-like family AMP2-3 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01035 RQRDPQQQYEQCQKRCQRRETEPRHMQICQQRCERRYEKEKRKQQ 45 Vicilin-like Antimicrobial peptide 2c-1 (MiAMP2c-1; Plant defensin) Q9SPL3 Belongs to the vicilin-like family AMP2-3 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01036 KRDPQQREYEDCRRHCEQQEPRLQYQCQRRCQEQQ 35 Vicilin-like Antimicrobial peptide 2d (MiAMP2d; Plant defensin) Q9SPL3 Belongs to the vicilin-like family AMP2-3 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2d has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01037 DPQTECQQCQRRCRQQESGPRQQQYCQRRCKEICEEEEEYN 41 Vicilin-like Antimicrobial peptide 2b (MiAMP2b; Plant defensin) Q9SPL5 Belongs to the vicilin-like family AMP2-1 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2b has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01038 RQRDPQQQYEQCQKHCQRRETEPRHMQTCQQRCERRYEKEKRKQQKRYEEQQREDEEKYEERMKEED 67 Vicilin-like Antimicrobial peptide 2c-3 (MiAMP2c-3; Plant defensin) Q9SPL5 Belongs to the vicilin-like family AMP2-1 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01039 RQRDPQQQYEQCQKHCQRRETEPRHMQTCQQRCERRYEKEKRKQQKR 47 Vicilin-like Antimicrobial peptide 2c-2 (MiAMP2c-2; Plant defensin) Q9SPL5 Belongs to the vicilin-like family AMP2-1 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01040 RQRDPQQQYEQCQKHCQRRETEPRHMQTCQQRCERRYEKEKRKQQ 45 Vicilin-like Antimicrobial peptide 2c-1 (MiAMP2c-1; Plant defensin) Q9SPL5 Belongs to the vicilin-like family AMP2-1 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2c has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml).##[NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)]" Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01041 KRDPQQREYEDCRRRCEQQEPRQQHQCQLRCREQQ 35 Vicilin-like Antimicrobial peptide 2d (MiAMP2d; Plant defensin) Q9SPL5 Belongs to the vicilin-like family AMP2-1 Macadamia integrifolia (Macadamia nut) "Antibacterial, Antifungal" Unknown Unknown Unknown Function: Antimicrobial peptides 2d has antibacterial and antifungal activity against a range of species (By similarity). "Gram-positive bacteria: (- Ca2+, + Ca2+): Clavibacter michiganensis (IC50=50, >50 ?g/ml);##Fungi (- Ca2+, + Ca2+): Alternaria helianthi (IC50=5-10, ND ?g/ml), Ceratocystis paradoxa (IC50=20-50, >50 ?g/ml), Cercospora nicotianae (IC50=5-10, 5※10 ?g/ml), Chalara elegans (IC50=2-5, 10※20 ?g/ml), Fusarium oxysporum (IC50=10, 20※50 ?g/ml), Leptosphaeria maculans (IC50=25, >50 ?g/ml), Sclerotinia sclerotiorum (IC50=20-50, >50 ?g/ml), Verticillium dahliae (IC50=5-10, >50 ?g/ml), Saccharomyces cerevisiae (IC50=20-50, >50 ?g/ml), Phytophthora cryptogea (IC50=5-10, 10※25 ?g/ml), Phytophthora parasitica nicotianae (IC50=10-20, >50 ?g/ml)##NOTE:, Ca2+ = Medium with low content of CaCl2 (50 ?M); + Ca2+ = Medium supplemented with high concentration of CaCl2 (1 mM)." Unknown 10571855 Plant J. 1999 Sep;19(6):699-710. "Marcus JP, Green JL, Goulter KC, Manners JM." A family of antimicrobial peptides is produced by processing of a 7S globulin protein in Macadamia integrifolia kernels. DRAMP01042 RHCESLSHRFKGPCTRDSNCASVCETERFSGGNCHGFRRRCFCTKPC 47 P322 (Plant defensin) No entry found Unknown Unknown Solanum tuberosum (potato tuber) unknow Bridge Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown PubMed ID is not available Plant Mol Biol 1988; 11:255-269. Stiekema WJ et al Louwerse JD. Molecular cloning and analysis of four potato tuber mRNAs. DRAMP01043 QICKAPSQTFPGLCFMDSSCRKYCIKEKFTGGHCSKLQRKCLCTKPC 47 TPP3 (Plant defensin) No entry found Unknown Unknown Lycopersicon esculentum Antifungal Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown 7647301 Plant Mol Biol 1995; 28:691-711. "Milligan SB, Gasser CS." Nature and regulation of pistil-expressed genes in tomato. DRAMP01044 KTCENLVDTYRGPCFTTGSCDDHCKNKEHLLSGRCRDDVRCWCTRNC 47 Defensin-like protein (Clone PSAS10; Plant defensin) P18646 Unknown Unknown Vigna unguiculata (cowpea seeds) Antifungal Bridge Unknown Unknown This protein is required for germination. No MICs found on DRAMP database Unknown 2103443 Plant Mol Biol. 1990 Jul;15(1):59-64. "Ishibashi N, Yamauchi D, Minamikawa T." Stored mRNA in cotyledons of Vigna unguiculata seeds: nucleotide sequence of cloned cDNA for a stored mRNA and induction of its synthesis by precocious germination. DRAMP01045 ITCGLVASKLAPCIGYLQGAPGPSAACCGGIKSLNSAAASPADRKTACTCLKSAATSMKGINYGKAASLPRQCGVSIPYAISPNTNCNAIH 91 IWF2 (Bv-LTP2; Plant defensin) No entry found Unknown IWF1 Beta vulgaris (Sugar beet) Antifungal Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. Also has fungicide activity. Fungi: Cercospora beticola. Lipid-binding 8790287 Plant Mol Biol. 1996 Jun;31(3):539-552. "Nielsen KK, Nielsen JE, Madrid SM, Mikkelsen JD." New antifungal proteins from sugar beet (Beta vulgaris L.) showing homology to non-specific lipid transfer proteins. DRAMP01046 GYGGHGGHGGHGGHGGHGGHGHGGGGHG 28 Shepherin I (fragement of shep-GRP; Plants) No entry found Unknown GRP Capsella bursa-pastoris (shepherd's purse) "Antibacterial, Antifungal" Unknown "Circular dichroism (CD) spectra of shepherin I showes that shepherin I in 50% trifluoroethanol has 66.7% random coils, without any alpha-helices." Unknown "Function: These antimicrobial peptides exhibit antimicrobial activity against Gram-negative bacteria and fungi. Tissue specificity: Expressed in roots but not in leaves and stems." "Gram-negative bacteria: Erwinia herbicola (IC50=62 ?g/ml), Escherichia coli (IC50<2.5 ?g/ml), Pseudomonas putida (IC50<2.5 ?g/ml), Pseudomonas syringae (IC50<2.5 ?g/ml), Salmonella typhimurium (IC50<2.5 ?g/ml), Serratia sp. (IC50=8 ?g/ml).##Fungi: Candida albicans (IC50=8 ?g/ml), Cryptococcus neoformans (IC50<2.5 ?g/ml), Saccharomyces cerevisiae (IC50<7 ?g/ml), Alternaria alternata (IC50<7 ?g/ml), Aspergillus flavus (IC50=65 ?g/ml), Fusarium culmorum (IC50=72 ?g/ml)." Unknown 11117262 Plant Mol Biol. 2000 Sep;44(2):187-197. "Park CJ, Park CB, Hong SS, Lee HS, Lee SY, Kim SC." "Characterization and cDNA cloning of two glycine- and histidine-rich antimicrobial peptides from the roots of shepherd's purse, Capsella bursa-pastoris." DRAMP01047 GYHGGHGGHGGGYNGGGGHGGHGGGYNGGGHHGGGGHG 38 shepherin II (fragement of shep-GRP; Plants) No entry found Unknown GRP Capsella bursa-pastoris (shepherd's purse) "Antibacterial, Antifungal" Unknown "Circular dichroism (CD) spectra of shepherin II showes that shepherin II in 50% trifluoroethanol has 75% random coils, without any alpha-helices." Unknown "Function: These antimicrobial peptides exhibit antimicrobial activity against Gram-negative bacteria and fungi. Tissue specificity: Expressed in roots but not in leaves and stems." "Gram-negative bacteria: Erwinia herbicola (IC50=25 ?g/ml), Escherichia coli (IC50<2.5 ?g/ml), Pseudomonas putida (IC50<2.5 ?g/ml), Pseudomonas syringae (IC50<2.5 ?g/ml), Salmonella typhimurium (IC50=65 ?g/ml), Serratia sp. (IC50<2.5 ?g/ml).##Fungi: Candida albicans (IC50=5 ?g/ml), Cryptococcus neoformans (IC50<2.5 ?g/ml), Saccharomyces cerevisiae (IC50=3 ?g/ml), Aspergillus flavus (IC50=60 ?g/ml), Fusarium culmorum (IC50=68 ?g/ml)." Unknown 11117262 Plant Mol Biol. 2000 Sep;44(2):187-197. "Park CJ, Park CB, Hong SS, Lee HS, Lee SY, Kim SC." "Characterization and cDNA cloning of two glycine- and histidine-rich antimicrobial peptides from the roots of shepherd's purse, Capsella bursa-pastoris." DRAMP01048 HTPTPTPICKSRSHEYKGRCIQDMDCNAACVKESESYTGGFCNGRPPFKQCFCTKPCKRERAAATLRWPGL 71 Sd5 (sugarcane defensin 5; Plant defensin) No entry found Unknown Unknown Saccharum officinarum (Sugarcane) Antifungal Combine helix and strand structure "Based on circular dichroism (CD) and nuclear magnetic resonance (NMR) spectroscopy showed that the structures of these Sds were compatible with alpha/beta proteins, a feature expected for plant defensins." 2KSK resolved by NMR. "Function: Sd5 is active against fungi, but not against bacteria." Fungi: Neurospora crassa and Fusarium solani (IC50=10-15 ?M). Unknown 18618271 Plant Mol Biol. 2008 Nov;68(4-5):321-335. "De-Paula VS, Razzera G, Medeiros L, Miyamoto CA, Almeida MS, Kurtenbach E, Almeida FC, Valente AP." Evolutionary relationship between defensins in the Poaceae family strengthened by the characterization of new sugarcane defensins. DRAMP01049 RHRHCFSQSHKFVGACLRESNCENVCKTEGFPSGECKWHGIVSKCHCKRIC 51 Sd3 (sugarcane defensin 3; Plant defensin) No entry found Unknown Unknown Saccharum officinarum (Sugarcane) Antifungal Combine helix and strand structure "Based on circular dichroism (CD) and nuclear magnetic resonance (NMR) spectroscopy showed that the structures of these Sds were compatible with alpha/beta proteins, a feature expected for plant defensins." Unknown "Function: Sd3 is active against fungi, but not against bacteria." Fungi: Neurospora crassa and Aspergillus niger (IC50=1-3.5 ?M). Unknown 18618271 Plant Mol Biol. 2008 Nov;68(4-5):321-335. "De-Paula VS, Razzera G, Medeiros L, Miyamoto CA, Almeida MS, Kurtenbach E, Almeida FC, Valente AP." Evolutionary relationship between defensins in the Poaceae family strengthened by the characterization of new sugarcane defensins. DRAMP01050 RYCLSQSHRFKGLCMSSSNCANVCQTENFPGGECKADGATRKCFCKKIC 49 Sd1 (sugarcane defensin 1; Plant defensin) B2CNV2 Unknown PDEF Saccharum officinarum (Sugarcane) Antifungal Combine helix and strand structure "Based on circular dichroism (CD) and nuclear magnetic resonance (NMR) spectroscopy showed that the structures of these Sds were compatible with alpha/beta proteins, a feature expected for plant defensins." Unknown "Function: Sd1 is active against fungi, but not against bacteria." "Fungi: Neurospora crassa, Aspergillus niger, Fusarium solani (IC50=1-2 ?M)." Unknown 18618271##PubMed ID is not available Plant Mol Biol. 2008 Nov;68(4-5):321-335.##Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases. "De-Paula VS, Razzera G, Medeiros L, Miyamoto CA, Almeida MS, Kurtenbach E, Almeida FC, Valente AP.##Padovan L, Segat L, Tossi A, Crovella S." Evolutionary relationship between defensins in the Poaceae family strengthened by the characterization of new sugarcane defensins.##Novel plant-defensin from sugarcane (Saccharum officinarum). DRAMP01051 KSTCKAESNTFPGLCITKPPCRKACLSEKFTDGKCSKILRRCICYKPC 48 NpThio1 (Plant defensin) No entry found Unknown Unknown Nicotiana excelsior Antifungal Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown PubMed ID is not available Plant Physiol 1997; 115:314. "Yamada S, Komori T, Imaseki H." unknow DRAMP01052 KDCKTESNTFPGICITKPPCRKACIKEKFTDGHCSKILRRCLCTKPC 47 NeThio2 (Plant defensin) No entry found Unknown Unknown Nicotiana excelsior Antifungal Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown PubMed ID is not available Plant Physiol 1997; 115:314. "Yamada S, Komori T, Imaseki H." unknow DRAMP01053 ATITFTNKCTRTVWPGG 17 Thaumatin-like protein (CdTLP; Plants) P84334 Unknown Unknown Cassia didymobotrya (Popcorn cassia) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity. Induction: By salicylic acid and by laminarin oligosaccharides. PTM: Contains one disulfide bond (By similarity)." "Fungi: Candida albicans 586 (EC50=6.2 ?M), Candida parapsilosis ATCC 22019 (EC50=2.2 ?M), Candida krusei ATCC 14243 (EC50=2.5 ?M), C. krusei 80 (EC50=5.4 ?M)." Unknown 17056265 Plant Physiol Biochem. 2006 Oct;44(10):604-610. "Vitali A, Pacini L, Bordi E, De Mori P, Pucillo L, Maras B, Botta B, Brancaccio A, Giardina B." Purification and characterization of an antifungal thaumatin-like protein from Cassia didymobotrya cell culture. DRAMP01054 QNICPRVNRIVTPCVAYGLGRAPIAPCCRALNDLRFVNTRNLRRAACRCLVGVVNRNPGLRRNPRFQNIPRDCRNTFVRPFWWRPRIQCGRINLTDKLIYLDAEE 105 Antimicrobial protein Ace-AMP1 (Ace-AMP1; Plant defensin) Q41258 Unknown Unknown Allium cepa (onion) "Antibacterial, Antifungal" Bridge Unknown Unknown "Function: Antifungal and antibacterial activity against the Gram-positive bacteria: B. megaterium and S. lutea. PTM: Contains four disulfide bonds 4-49; 14-26; 28-73; 47-89." "Gram-positive bacteria: Bacillus megaterium, Sarcina Lutea.##Fungi (SMF-, SMF+): Alternaria brassicola (IC50=2.5, 1.5 ?g/ml), Ascockyta pisi (IC50=1, 10 ?g/ml), Botrytis cinerea (IC50=3, 7 ?g/ml), Colletotrickum lindemutkianum (IC50=1.5, 1.5 ?g/ml), Fusarium culmorum (IC50=6, 10 ?g/ml), Fusarium oxysporum fsp. pisi (IC50=3.5, 4 ?g/ml), Fusarium oxysporum fsp. lycopersici (IC50=3, 10 ?g/ml),Nectria haematococca (IC50=3.5, 7 ?g/ml),Phoma betae (IC50=1.5, 7 ?g/ml), Pyrenopkora tritici-repentis (IC50=3, 3.5 ?g/ml), Pyricularia oryzae (IC50=3, 7 ?g/ml), Verticillium dahliae (IC50=0.25, 0.5 ?g/ml).##[NOTE: SMF- = Synthetic growth Medium with low ionic strength; SMF+ = Synthetic growth Medium supplemented with with 1 mM CaCl2, 50 mM KC1]" Unknown 7480341##9521681 Plant Physiol. 1995 Oct;109(2):445-455.##Biochemistry. 1998 Mar 17;37(11):3623-3637. "Cammue BP, Thevissen K, Hendriks M, Eggermont K, Goderis IJ, Proost P, Van Damme J, Osborn RW, Guerbette F, Kader JC, et al.##Tassin S, Broekaert WF, Marion D, Acland DP, Ptak M, Vovelle F, Sodano P." "A potent antimicrobial protein from onion seeds showing sequence homology to plant lipid transfer proteins.##Solution structure of Ace-AMP1, a potent antimicrobial protein extracted from onion seeds. Structural analogies with plant nonspecific lipid transfer proteins." DRAMP01055 AGCIKNGGRCNASAGPPYCCSSYCFQIAGQSYGVCKNR 38 P. americana AMP (Pa-AMP-1; PAFP-S; Cys-rich; Plant defensin) "P81418, O82728" Belongs to the AMP family Unknown Phytolacca americana (American pokeweed) (Phytolacca decandra) "Antibacterial, Antifungal" Beta strand (3 strands; 13 residues) "The global fold involves a cystine-knotted three-stranded antiparallel beta-sheet (residues 8-10, 23-27, 32-36), a flexible loop (residues 14-19), and four beta-reverse turns (residues 4-8, 11-14, 19-22, 28-32). This structure features all the characteristics of the knottin fold. It is the first structural model of an antifungal peptide that adopts a knottin-type structure. " 1DKC resolved by NMR. "Function: Possesses antifungal activity. Tissue specificity: Seed specific. Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. PTM: Contains three disulfide bonds: 3-20; 10-24; 19-35. " "Gram-positive bacteria: Bacillus megaterium (IC50=8 ?g/ml), Staphyanococcus sp. (IC50=11 ?g/ml).##Fungi: Alternaria panax, Fusarium sp., Rhizoctonia solani." Unknown 10759497##11551192 Plant Physiol. 2000 Apr;122(4):1015-1024.##Biochemistry. 2001 Sep 18;40(37):10973-10978. "Liu Y, Luo J, Xu C, Ren F, Peng C, Wu G, Zhao J.##Gao GH, Liu W, Dai JX, Wang JF, Hu Z, Zhang Y, Wang DC." "Purification, characterization, and molecular cloning of the gene of a seed-specific antimicrobial protein from pokeweed.##Solution structure of PAFP-S: a new knottin-type antifungal peptide from the seeds of Phytolacca americana." DRAMP01056 ELCEKASQTWSGTCGKTKHCDDQCKSWEGAAHGACHVRDGKHMCFCYFNC 50 Ha-DEF1 (H. annuus defensin 1; Plants) No entry found Unknown Unknown Helianthus annuus (sunflower) Antifungal Unknown Unknown Unknown No comments found on DRAMP database Fungi: Saccharomyces cerevisiae. Unknown 17375322 Planta. 2007 Aug;226(3):591-600. "de Z??licourt A, Letousey P, Thoiron S, Campion C, Simoneau P, Elmorjani K, Marion D, Simier P, Delavault P." "Ha-DEF1, a sunflower defensin, induces cell death in Orobanche parasitic plants." DRAMP01057 XXTKFDFFTLALQXPAXF 18 30 kDa antifungal protein (Plants) Q10722 Unknown Unknown Engelmannia peristenia (Engelmann's daisy) (Engelmannia pinnatifida) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity against the plant fungal pathogens. Does not have antifungal activity against the human pathogen C. albicans. Does not have ribonuclease activity. Tissue specificity: Leaves. Developmental stage: Expressed in young plants, no expression in mature plants. Miscellaneous: Resistant to heat and proteolysis. Biophysicochemical properties: Temperature dependence (Thermostable)." "Fungi: Gaeumannomyces graminis, Phytophthora infestans, Phytophthora megasperma, Sclerotinia sclerotiorum." Unknown 8670144 Biochem J. 1996 Jun 15;316 ( Pt 3):723-727. "Huynh QK, Borgmeyer JR, Smith CE, Bell LD, Shah DM." Isolation and characterization of a 30 kDa protein with antifungal activity from leaves of Engelmannia pinnatifida. DRAMP01058 ATFDIQNKXTYTVWAAAWAPSYPGGXKQLD 30 Antifungal protein (Plants) P84061 Unknown Unknown Diospyros texana (Texas persimmon) Antifungal Unknown Unknown Unknown "Function: Has antifungal activity against P. infestans. Tissue specificity: Expressed in the skin and the flesh but not the seed of the fruit. Developmental stage: Overripe fruit." Phytophthora infestans. Unknown 8048935 Biochem Biophys Res Commun. 1994 Jul 29;202(2):666-672. "Vu L, Huynh QK." Isolation and characterization of a 27-kDa antifungal protein from the fruits of Diospyros texana. DRAMP01059 VLSHNNESSYSDTSSCTSQ 19 Putative antimicrobial protein 1 (Plants) B3EWI5 Unknown Unknown Cenchritis muricatus (Beaded periwinkle) Antimicrobial Unknown Unknown Unknown Function: May have antimicrobial activity. No MICs found on DRAMP database Unknown 22367403 Curr Microbiol. 2012 May;64(5):501-505. "L車pez-Abarrategui C, Alba A, Lima LA, Maria-Neto S, Vasconcelos IM, Oliveira JT, Dias SC, Otero-Gonzalez AJ, Franco OL." Screening of antimicrobials from Caribbean sea animals and isolation of bactericidal proteins from the littoral mollusk Cenchritis muricatus. DRAMP01060 DLPECCSATELELDSGKQTS 20 Putative antimicrobial protein 2 (Plants) B3EWI6 Unknown Unknown Cenchritis muricatus (Beaded periwinkle) Antimicrobial Unknown Unknown Unknown Function: May have antimicrobial activity. No MICs found on DRAMP database Unknown 22367403 Curr Microbiol. 2012 May;64(5):501-505. "L車pez-Abarrategui C, Alba A, Lima LA, Maria-Neto S, Vasconcelos IM, Oliveira JT, Dias SC, Otero-Gonzalez AJ, Franco OL." Screening of antimicrobials from Caribbean sea animals and isolation of bactericidal proteins from the littoral mollusk Cenchritis muricatus. DRAMP01062 SESILIVHQQQSRSSGS 17 Putative antimicrobial protein 3 (Cm-p2; Plants) B3EWI8 Unknown Unknown Cenchritis muricatus (Beaded periwinkle) Antifungal Unknown Unknown Unknown "Function: This peptide demonstrated the capacity to prevent the development of yeasts and filamentous fungi. Otherwise, Cm-p1 displayed no toxic effects against mammalian cells." No MICs found on DRAMP database Unknown 22210491 Biochimie. 2012 Apr;94(4):968-974. "L??pez-Abarrategui C, Alba A, Silva ON, Reyes-Acosta O, Vasconcelos IM, Oliveira JT, Migliolo L, Costa MP, Costa CR, Silva MR, Garay HE, Dias SC, Franco OL, Otero-Gonz??lez AJ." Functional characterization of a synthetic hydrophilic antifungal peptide derived from the marine snail Cenchritis muricatus. DRAMP01065 NSMERVEELRKKLQD 15 Chitin-binding protein HM30 (Plants) P83630 Belongs to the parathyroid hormone family Unknown Hydrangea macrophylla (Bigleaf hydrangea) Antifungal Unknown Unknown Unknown Function: Has antifungal activity against phytopathogenic fungi. Has no chitinase or agglutination activities. "Fungi: Alternria alternate, Alternaria cucumerina, Aspergillus niger, Collectotrichum gossypii, Fusarium oxysporum, F. oxysporum subsp melonis, Fusarium moniliforme, Thanatephorus cucumeris, Verticillium dahliae, Pyricularia oryzae Cav.." Chitin-binding 11812226 Protein Expr Purif. 2002 Feb;24(1):76-82. "Yang Q, Gong ZZ." Purification and characterization of an ethylene-induced antifungal protein from leaves of Guilder rose (Hydrangea macrophylla). DRAMP01067 KQTENLADTY 10 Coccinin (Plant defensin) P84785 Belongs to the DEFL family Unknown Phaseolus coccineus (Scarlet runner bean) (Phaseolus multiflorus) "Antifungal, Antiviral" Unknown Unknown Unknown Function: Has strong antifungal activity. Inhibits the proliferation of leukemia cells in vitro. Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase (IC50=41 ?M). Lacks mitogenic activity towards murine splenocytes. "Fungi: Fusarium oxysporum (IC50=81㊣7 ?M), Mycosphaerella arachidicola (IC50=75㊣5 ?M), Physalospora piricola (IC50=89㊣4 ?M), Rhizoctomia solani (IC50=134㊣2 ?M), Botrytis cinerea (IC50=109㊣5 ?M), Coprinus comatus (IC50=122㊣7 ?M)." Unknown 15572193 Peptides. 2004 Dec;25(12):2063-2068. "Ngai PH, Ng TB." "Coccinin, an antifungal peptide with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from large scarlet runner beans." DRAMP01068 LNCGQVDSKMKPCLTYVQGGPGPSGECCNGVRDLHNQAQSSGDRQTVCNCLKGIARGIHNLNLNNAASIPSKCNVNVPYTISPDIDCSRIY 91 Non-specific lipid-transfer protein (Plant defensin) A8YPK3 Belongs to the plant LTP family ltp1 Hordeum vulgare (Barley) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding PubMed ID is not available Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Niessen L. Behaviour of foam components in gushing beer. DRAMP01069 MADKGVGSRLSALFLLVLLVISIGMMQLEPAEGRTCKTPSGKFKGVCASRNNCKNVCQTEGFPSGSCDFHVANRKCYCSKPCP 83 Putative plant defensin SPI1B (Plants; Predicted) Q8GTL2 Unknown Unknown Picea abies (Norway spruce) (Picea excelsa) Antimicrobial Unknown Unknown Unknown No comments found on DRAMP database No MICs found on DRAMP database Unknown PubMed ID is not available Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases Fossdal CG. The putative gymnosperm plant defensin (SPI1) accumulates after seed germination and a related SPI1B cDNA is found in needles. DRAMP01070 AIPCGQVNSALASCVSYAKGSGASPPGACCSGVRRLAGLARSTADKQAACRCIKSAAGGLNPGKAASIPSKCGVSIPYSISASVDCSKIH 90 Non-specific lipid-transfer protein (Plants;Predicted) Q1KMV1 Belongs to the plant LTP family Unknown Triticum aestivum (Wheat) Antifungal Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding 18257684 Mol Plant Microbe Interact. 2008 Mar;21(3):346-360. "Sun JY, Gaudet DA, Lu ZX, Frick M, Puchalski B, Laroche A." Characterization and antifungal properties of wheat nonspecific lipid transfer proteins. DRAMP01071 AISCGQVASAIAPCISYARGQGSAPSAGCCSGVRSLNNAARTTADRRAACNCLKNAAAGVSGLNAGNAASIPSKCGVSIPYTISTSTDCSRVN 93 Non-specific lipid-transfer protein (Plants;Predicted) Q2XX14 Belongs to the plant LTP family plt1 Zea mays subsp. parviglumis (Balsas teosinte) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding 16120802 Mol Biol Evol. 2005 Dec;22(12):2480-2490. "Moeller DA, Tiffin P." Genetic diversity and the evolutionary history of plant immunity genes in two species of Zea. DRAMP01072 AISCGQVASAIAPCISYARGQGSGPSAGCCSGVKSLNNAARTTADRRAACNCLKNAAAGVSGLNAGNAASIPSKCGVSIPYTISTSTDCSRVN 93 Non-specific lipid-transfer protein (Plants;Predicted) Q2XX25 Belongs to the plant LTP family plt1 Zea mays subsp. parviglumis (Balsas teosinte) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding 16120802 Mol Biol Evol. 2005 Dec;22(12):2480-2490. "Moeller DA, Tiffin P." Genetic diversity and the evolutionary history of plant immunity genes in two species of Zea. DRAMP01073 AISCGQVNSALASCVSYAKGSGASPPGACCSGVRRLAGLARSTADKQAACRCIKSAAGGLNPGKAASIPSKCGVSIPYSISASVDCSKIH 90 Non-specific lipid-transfer protein (Plants;Predicted) Q9FUK0 Belongs to the plant LTP family LTP1 Triticum aestivum (Wheat) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding PubMed ID is not available Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases "Seo Y.W, Jang C.S." Isolation and characterization of lipid transfer protein in wheat. DRAMP01074 AISCGQVNSALGPCISYARGSGANTSAACCSGVKRLAGSVRTSDDKKAACLCIKRAAGGLNPGKAADIPTKCRVTIPYKISSNVNCNNLH 90 Non-specific lipid-transfer protein (Plants;Predicted) Q155V0 Belongs to the plant LTP family Unknown Secale cereale (Rye) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding 16823370 Nat Biotechnol. 2006 Jul;24(7):852-855. "Doxey AC, Yaish MW, Griffith M, McConkey BJ." Ordered surface carbons distinguish antifreeze proteins and their ice-binding regions. DRAMP01075 AISCGQVSSALSPCISYARGSGSSPPAACCSGVRSLAGAARSTADKQAACKCIKSAAGGLNAGKAAGIPSKCGVSIPYAISSSVDCSKIR 90 Non-specific lipid-transfer protein (Plants;Predicted) Q1KMU9 Belongs to the plant LTP family LTP Triticum aestivum (Wheat) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding 18257684 Mol Plant Microbe Interact. 2008 Mar;21(3):346-360. "Sun JY, Gaudet DA, Lu ZX, Frick M, Puchalski B, Laroche A." Characterization and antifungal properties of wheat nonspecific lipid transfer proteins. DRAMP01076 AISCGQVSSALTPCVAYAKGSGTSPSGACCSGVRKLAGLARSTADKQATCRCLKSVAGGLNPNKAAGIPSKCGVSVPYTISASVDCSKIH 90 Non-specific lipid-transfer protein (Plants;Predicted) Q9ATG4 Belongs to the plant LTP family LTP2 Triticum aestivum (Wheat) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding PubMed ID is not available Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases "Seo Y.W, Jang C.S, Bu S.Y, Kim J.B." Isolation and characterization of lipid transfer protein in wheat. DRAMP01077 AITCGQVNSAVGPCLTYARGGAGPSAACCSGVRSLKAAASSTADRRTACNCLKNAARGIKGLNAGNAASIPSKCGVSVPYTISASIDCSRVS 92 Non-specific lipid-transfer protein (Plants;Predicted) Q2RBD2 Belongs to the plant LTP family Unknown Oryza sativa subsp. japonica (Rice) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding 16188032 BMC Biol. 2005 Sep 27;3:20. Rice Chromosomes 11 and 12 Sequencing Consortia. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications." DRAMP01078 AITCGQVSSAIAPCLSYARGTGSGPSASCCSGVRNLKSAASTAADRRAACNCLKNAARGVSGLNAGNAASIPSKCGVSIPYTISTSTDCSRVN 93 Non-specific lipid-transfer protein (Plants;Predicted) O24583 Belongs to the plant LTP family Unknown Zea mays (Maize) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding 19936069 PLoS Genet. 2009 Nov;5(11):e1000740. "Soderlund C, Descour A, Kudrna D, Bomhoff M, Boyd L, Currie J, Angelova A, Collura K, Wissotski M, Ashley E, Morrow D, Fernandes J, Walbot V, Yu Y." "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs." DRAMP01079 AITCGQVSSALSPCIPYARGNGANPSAACCSGVRRIAGAVQSTADKKTACNCIKRAAGGLNAGKAADIPSKCSVSIPYAINPSVDCSTIR 90 Non-specific lipid-transfer protein (Plants;Predicted) Q155V1 Belongs to the plant LTP family Unknown Secale cereale (Rye) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding 16823370 Nat Biotechnol. 2006 Jul;24(7):852-855. "Doxey AC, Yaish MW, Griffith M, McConkey BJ." Ordered surface carbons distinguish antifreeze proteins and their ice-binding regions. DRAMP01080 AITCGQVTHNVAPCFNYVKSGGAVPAACCKGVSNLNSMAKTTADRQQTCNCLKSAAGSIKGLNANLAAGLPGKCGVNVPYKISTSTNCNNVK 92 Non-specific lipid-transfer protein (Plants;Predicted) Q4PLT5 Belongs to the plant LTP family LTP6 Fragaria ananassa (Strawberry) Antimicrobial Unknown Unknown Unknown Function: Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). No MICs found on DRAMP database Lipid-binding PubMed ID is not available Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases "Zuidmeer L, Salentijn EMJ." Cross-reactivity of a recombinant non-specific lipid transfer protein from strawberry. DRAMP18120 PPTQNPSMAPPTQNPYGQPMTPPTQNPYGQPMAPP 35 BnPRP1 (Plant defensin) No entry found BnPRP1 Brassica napus "Antibacterial, Antifugal" Unknown Unknown Unknown "BnPRP1 has 40.5% identity with a known proline-rich antimicrobial peptide SP-B from the pig. BnPRP1 isolated from B. napus was the first PR-AMP member that was characterized in plants, and its homology sequences were found in some other Brassicaceae plants by the genome sequences analysis. " "Gram-positive: M. luteus (MIC= 16.9 ?㊣ 2.7 uM );##Gram-negative: E. coli (MIC= 8.4 ?㊣ 1.4 uM);## Fungi:Sclerotinia sclerotiorum, Mucor sp., Magnaporthe oryzae and Botrytis cinerea" Unknown 26383098 PLoS One.??2015 Sep 18;10(9):e0137414. "Cao H, Ke T, Liu R, et al." Identification of a Novel Proline-Rich Antimicrobial Peptide from Brassica napus. DRAMP18507 FSGGNCRGFRRRCFCTK 17 "SolyC (Plant defensin; tomato, plants)" No entry found Belongs to the tomato defensin family Unknown Tomato "Antibacterial, Anti-Gram+, Anti-Gram-" Beta sheet Unknown Unknown "Function: Antibacterial activity against a panel of human pathogens, including H.pylori, and displays anti-inflammatory activity in vitro." "[Ref.23124812]Gram-positive bacteria: Staphylococcus aureus A170 (MIC=40 " Unknown 23124812 J Pept Sci. 2012 Dec;18(12):755-62. "Rigano MM, Romanelli A, Fulgione A, Nocerino N, D'Agostino N, Avitabile C, Frusciante L, Barone A, Capuano F, Capparelli R." A novel synthetic peptide from a tomato defensin exhibits antibacterial activities against Helicobacter pylori. DRAMP20795 XTCESPSHKFKGPCATNRNCES 22 "So-D1 (S. oleracea defensin 1; spinach defensins, plants)" P81572 Belongs to the DEFL family. Group II subfamily. Unknown Spinacia oleracea (Spinach) Antibacterial Bridge Unknown Unknown Function: Antimicrobial peptide. Active against Gram-positive and Gram-negative bacteria pathogens. Gram-positive bacterium: Clavibacter michiganensis (EC50=1 Unknown 9762899 FEBS Lett. 1998 Sep 18;435(2-3): 159-162. "Segura A, Moreno M, Molina A, Garcia-Olmedo F" Novel defensin subfamily from spinach (Spinacia oleracea). DRAMP20796 GIFSNMYXRTPAGYFRGPXGYXXN 24 "So-D6 (S. oleracea defensin 6, spinach defensins; plants)" P81567 Belongs to the DEFL family. Group II subfamily. Unknown Spinacia oleracea (Spinach) Antibacterial Bridge Unknown Unknown "Function: Antimicrobial activity against Fungi, Gram-positive and Gram-negative bacteria. Tissue specificity: Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots. Developmental stage: Present throughout the life of the leaf." Gram-positive bacterium: Clavibacter michiganensis (EC50=1 Unknown 9762899 FEBS Lett. 1998 Sep 18;435(2-3): 159-162. "Segura A, Moreno M, Molina A, Garcia-Olmedo F" Novel defensin subfamily from spinach (Spinacia oleracea). DRAMP21203 HLNKRVQRELIGWLDWLK 18 "AmyI-1-18 (Oryza sativa L., Angiospermae, Plants)" P17654 Belongs to the glycosyl hydrolase 13 family. AMY1.1 Oryza sativa subsp. japonica (Rice) "Antimicrobial, Antibacterial, Anti-gram-, Antifungal" Alpha helix Unknown None Function: Antibacterial activity against Gram-negative bacteria. Antifungal activity gaginst Candida albicans. Important for breakdown of endosperm starch during germination. [Ref.27478151] Gram-negative bacteria : Porphyromonas gingivalis(IC50=13㊣3 米M). ##[Ref.26850838] Fungi: Candida albicans(IC50=64㊣2 米M) Unknown 27478151##26850838 J Biosci Bioeng. 2016 Dec;122(6):652-659. doi: 10.1016/j.jbiosc.2016.05.008. ##Biopolymers. 2016 Mar;106(2):219-229. doi: 10.1002/bip.22817. "Taniguchi M, Ochiai A, Takahashi K, Nakamichi SI, Nomoto T, Saitoh E, Kato T, Tanaka T" "Antimicrobial activity against Porphyromonas gingivalis and mechanism of action of the cationic octadecapeptide AmyI-1-18 and its amino acid-substituted?analogs. ##Effect of alanine, leucine, and arginine substitution on antimicrobial activity against candida albicans and action mechanism of a cationic octadecapeptide derived from 汐-amylase of rice." DRAMP29089 AFIQLSKPCISDKECSIVKNYRARCRKGYCVRRRIR 36 NCR044 (Putative Late nodulin) A0A396GSL0 Not found MtrunA17_Chr7g02162 Medicago truncatula (Barrel medic) (Medicago tribuloides) "Antimicrobial, Antifungal" 汐-helix and 汕-sheet "NCR044 contains one short (A23 to R25, G28 to C30) antiparallel 汕-sheet and a whiff (S11 to E14) of an 汐-helix." 6U6G "Comment: The oxidized form of the NCR044 peptide exhibits potent broad-spectrum antifungal activity in vitro against four economically important fungal pathogens tested in this study. Many factors can strongly affect the efficacy of antifungal peptides. For example, disulfide bonds can help to increase potency of the oxidized form of NCR044. For deployment of NCR044 in crop protection, one could envisage further manipulating the cationicity/hydrophobicity of the oxidized or reduced NCR044 through site-directed mutagenesis and increase its antifungal potency on the surface of plant tissues without causing phytotoxicity." "[Ref.32571919] Fungi: Botrytis cinerea (IC50 = 1.55 ㊣ 0.21 米M, IC90 = 2.72 ㊣ 0.05 米M), Fusarium graminearum (IC50 = 1.93 ㊣ 0.23 米M, IC90 = 2.80 ㊣ 0.04 米M), F.virguliforme (IC50 = 1.68 ㊣ 0.20 米M, IC90 = 2.70 ㊣ 0.08 米M), F.oxysporum (IC50 = 0.52 ㊣ 0.01 米M, IC90 = 0.71 ㊣ 0.01 米M)" Multiple membrane phospholipids 32571919 Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16043-16054. doi: 10.1073/pnas.2003526117. Epub 2020 Jun 22. "Velivelli SLS, Czymmek KJ, Li H, Shaw JB, Buchko GW, Shah DM" Antifungal symbiotic peptide NCR044 exhibits unique structure and multifaceted mechanisms of action that confer plant protection DRAMP29091 GRTSKQELCTWERGSVRQADKTIAG 25 Skh-AMP1 No entry found "Belongs to the Lamiaceae family, subfamily Nepetoideae." N/A Satureja khuzistanica "Antimicrobial, Antifungal" 汐-helical "Evaluation of the peptide three-dimensional structure showed that, despite the unusual distribution of amino acids in the Wheel projection, Skh-AMP1 maybe forms a 汐-helix structure with more hydrophobic C-terminal than that of the N-terminal. " None "Comment: The antifungal activity of Skh-AMP1 may be related to its ability to disrupt fungal cell membrane permeabilization and induce enhanced ROS production. Therefore, Skh-AMP1 can be introduced as a novel antifungal candidate for developing new therapeutic agents." "[Ref.31128493] Fungi: Candida albicans ATCC 10231 (MIC = 21.6 米M, MFC = 43.2 米M), Candida krusei DSM 70079 (MIC = 20.7 米M, MFC = 41.4 米M), Candida glabrata ATCC 90030 (MIC = 19.8 米M, MFC = 39.6 米M), Aspergillus niger ATCC 9029 (MIC = 22.5 米M, MFC = 45 米M), Aspergillus flavus PFCC 100 (MIC = 23.4 米M, MFC = 58.5 米M), Aspergillus fumigatus Af 293 (MIC = 20.7 米M, MFC = 41.4 米M)" Fungal membrane 31704210##31128493 Peptides. 2020 Jan;123:170195. doi: 10.1016/j.peptides.2019.170195. Epub 2019 Nov 6.##Phytochemistry. 2019 Aug;164:136-143. doi: 10.1016/j.phytochem.2019.05.011. Epub 2019 May 23. "Khani S, Seyedjavadi SS, Hosseini HM, Goudarzi M, Valadbeigi S, Khatami S, Ajdary S, Eslamifar A, Amani J, Imani Fooladi AA, Razzaghi-Abyaneh M##Soghra Khani, Sima Sadat Seyedjavadi, Hadi Zare-Zardini, Hamideh Mahmoodzadeh Hosseini, Mehdi Goudarzi, Shohreh Khatami, Jafar Amani, Abbas Ali Imani Fooladi, Mehdi Razzaghi-Abyaneh" "Effects of the antifungal peptide Skh-AMP1 derived from Satureja khuzistanica on cell membrane permeability, ROS production, and cell morphology of conidia and hyphae of Aspergillus fumigatus. ##Isolation and functional characterization of an antifungal hydrophilic peptide, Skh-AMP1, derived from Satureja khuzistanica leaves"