General Information

    • DRAMP ID

    • DRAMP01165

    • Peptide Name

    • Preprotemporin-1SKa (Frogs, amphibians, animals)

    • Source

    • Rana sakuraii (Japanese brown frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FLPVILPVIGKLLNGILGK

    • Sequence Length

    • 19

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Predicted

    • SMILES

    • CC[C@@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@H](C)CC)C(C)C)[C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • PDB ID

    • Predicted Structure

    • There is no predicted structure for DRAMP01165.

Physicochemical Information

    • Formula

    • C99H170N22O21

    • Absent Amino Acids

    • ACDEHMQRSTWY

    • Common Amino Acids

    • L

    • Mass

    • 2004.57

    • PI

    • 10

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +2

    • Boman Index

    • 35.5

    • Hydrophobicity

    • 1.474

    • Aliphatic Index

    • 194.74

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP01165

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii.

    • Reference

    • Peptides. 2007 Mar;28(3):505-514.

    • Author

    • Suzuki H, Iwamuro S, Ohnuma A, Coquet L, Leprince J, Jouenne T, Vaudry H, Taylor CK, Abel PW, Conlon JM.