• • DRAMP ID

  • DRAMP01199

• • Peptide Name

  • Hejiangin-A1 (Frogs, amphibians, animals)

• • Source

  • Odorrana hejiangensis

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • RFIYMKGFGKPRFGKR

• • Sequence Length

  • 16

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • SMILES

  • CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-negative bacteria:

      Target Organism	Activity
      Escherichia coli ATCC 25922	MIC=100 µg/ml
      Bacillus pyocyaneus CMCCB 10104 (MIC=25 µg/ml);	-

    • Gram-positive bacterium:

      Target Organism	Activity
      Staphylococcus aureus ATCC 25923	MIC=25 µg/ml

    • Yeast:

      Target Organism	Activity
      Candida albicans ATCC 2002	MIC=50 µg/ml

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

• Predicted Structure

• There is no predicted structure for DRAMP01199.

DRAMP01199

• • Function

  • Hejiangin-A1 showes killing effects against the tested strains.

• ·Literature 1

• • Title

  • Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs.

• • Pubmed ID

  • 22029824

• • Reference

  • J Proteome Res. 2012 Jan 1;11(1):306-319.

• • Author

  • Yang X, Lee WH, Zhang Y.