• • DRAMP ID

  • DRAMP01591

• • Peptide Name

  • Citropin 1.1 M15 (Frogs, amphibians, animals)

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • GLFAVIKKVASVIKKL

• • Sequence Length

  • 16

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • SMILES

  • CC[C@@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)CN)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@H](C)CC)C(C)C)C(C)C

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacterium:

      Target Organism	Activity
      E. coli (MIC=53 µM);	-

    • Gram-positive bacteria:

      Target Organism	Activity
      S. aureus	MIC=3 µM
      B. subtilis	MIC=3 µM

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

• Predicted Structure

• There is no predicted structure for DRAMP01591.

DRAMP01591

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin, and maculatin.

• • Pubmed ID

  • 20564028

• • Reference

  • Biopolymers. 2011;96(2):147-157.

• • Author

  • Chia CS, Gong Y, Bowie JH, Zuegg J, Cooper MA.