General Information

    • DRAMP ID

    • DRAMP02197

    • Peptide Name

    • Ranatuerin-2SRa (Frogs, amphibians, animals)

    • Source

    • Rana sierrae (Nevada yellow-legged frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • MFTMKKSLLLFFFLGTISLSLCEEERGADEDDGVELTEEEVKRGLLSSFKGVAKGVAKDLAGKLLEKLKCKITGC

    • Sequence Length

    • 75

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02197 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02197.

Physicochemical Information

    • Formula

    • C366H605N91O111S5

    • Absent Amino Acids

    • HNPQWY

    • Common Amino Acids

    • L

    • Mass

    • 8216.67

    • PI

    • 5.43

    • Basic Residues

    • 12

    • Acidic Residues

    • 13

    • Hydrophobic Residues

    • 28

    • Net Charge

    • -1

    • Boman Index

    • -80.63

    • Hydrophobicity

    • 0.056

    • Aliphatic Index

    • 98.8

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 1.69

    • Polar Residues

    • 20

DRAMP02197

DRAMP02197 chydropathy plot

Comments Information

    • Amphibian defense peptide.

Literature Information

  • ·Literature 1

    • Title

    • Non-lethal collection of skin secretions for expression analysis and identification of antimicrobial peptide transcripts from six North American frog species.

    • Reference

    • Dis. Aquat. Organ. 2013,0:0-0.

    • Author

    • Robertson LS, Fellers GM, Marranca JM, Kleeman PM.