General Information

    • DRAMP ID

    • DRAMP02400

    • Peptide Name

    • Antimicrobial peptide AJN-10 (AJN-10)

    • Source

    • Anguilla japonica (Japanese eel)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GCPQTPRCTNYAEKGQCPPN

    • Sequence Length

    • 20

    • Protein Existence

    • Protein level

    • SMILES

    • Not available

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-

    • Target Organism

      • Gram-negative bacterium:
        Target OrganismActivity
        Aeromonas hydrophila-

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02400.

Physicochemical Information

    • Formula

    • C88H138N28O30S3

    • Absent Amino Acids

    • DFHILMSVW

    • Common Amino Acids

    • P

    • Mass

    • 2164.41

    • PI

    • 7.95

    • Basic Residues

    • 2

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 1

    • Net Charge

    • +1

    • Boman Index

    • -49.39

    • Hydrophobicity

    • -1.325

    • Aliphatic Index

    • 5

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1615

    • Absorbance 280nm

    • 85

    • Polar Residues

    • 10

DRAMP02400

Comments Information

    • Function

    • Displays antimicrobial activity against the Gram-negative bacterium A.hydrophila.

Literature Information

  • ·Literature 1

    • Title

    • Isolation and identification of a novel inducible antibacterial peptide from the skin mucus of Japanese eel, Anguilla japonica.

    • Reference

    • Protein J. 2011 Aug;30(6):413-421.

    • Author

    • Liang Y, Guan R, Huang W, Xu T.