• • DRAMP ID

  • DRAMP02998

• • Peptide Name

  • Apidaecin-1A (Apidaecin IA; Insects, animals)

• • Source

  • Apis mellifera (Honeybee)

• • Family

  • Belongs to the apidaecin family

• • Gene

  • APID73

• • Sequence

  • GNNRPVYIPQPRPPHPRI

• • Sequence Length

  • 18

• • UniProt Entry

  • Q06602,P11525,P11526

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacteria:

      Target Organism	Activity
      Agrobacterium tumefaciens	MIC=0.2 µg/ml
      Erwinia salicis	MIC=0.02 µg/ml
      Escherichia coli	MIC=0.1 µg/ml
      Pseudomonas syringae	MIC=0.2 µg/ml
      Rhizobium meliloti	MIC=0.1 µg/ml
      Salmonella Newport	MIC=0.2 µg/ml
      Salmonella typhimurium	MIC=0.1 µg/ml
      Shigella flexneri (MIC=0.1 µg/ml);	-

    • Gram-positive bacteria:

      Target Organism	Activity
      Corynebacterium insidiosum	MIC=50 µg/ml
      Bacillus megaterium	MIC=150 µg/ml

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP02998_predicted_structure.pdb to download.

DRAMP02998

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Apidaecins: antibacterial peptides from honeybees.

• • Pubmed ID

  • 2676519

• • Reference

  • EMBO J. 1989 Aug;8(8):2387-2391.

• • Author

  • Casteels P, Ampe C, Jacobs F, Vaeck M, Tempst P.