General Information

    • DRAMP ID

    • DRAMP03757

    • Peptide Name

    • Amphipathic peptide Tx348 (BoiTx348; Arthropods, animals)

    • Source

    • Buthus occitanus israelis (Common yellow scorpion)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FIMDLLGKIF

    • Sequence Length

    • 10

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP03757 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03757.

Physicochemical Information

    • Formula

    • C59H93N11O13S

    • Absent Amino Acids

    • ACEHNPQRSTVWY

    • Common Amino Acids

    • FIL

    • Mass

    • 1196.51

    • PI

    • 5.84

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 6

    • Net Charge

    • 0

    • Boman Index

    • 14.66

    • Hydrophobicity

    • 1.63

    • Aliphatic Index

    • 156

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 1

DRAMP03757

Comments Information

    • PTM

    • C-terminal amidation and Cleavage on pair of basic residues.

    • Function

    • Amphipathic peptide that shows antibacterial acitivities.

Literature Information

  • ·Literature 1

    • Title

    • Buthus occitanus israelis scorpion toxin.

    • Reference

    • Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases

    • Author

    • Zilberberg N, Kozminsky-Atias A.