General Information

    • DRAMP ID

    • DRAMP03770

    • Peptide Name

    • OcyC2f (one chain of Non-disulfide-bridged peptide 5.8; Arthropods, animals)

    • Source

    • isthacanthus cayaporum (South American scorpion)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GILGKIWEGVKS

    • Sequence Length

    • 12

    • Protein Existence

    • Protein level

    • SMILES

    • Not available

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03770.

Physicochemical Information

    • Formula

    • C60H99N15O16

    • Absent Amino Acids

    • ACDFHMNPQRTY

    • Common Amino Acids

    • G

    • Mass

    • 1286.54

    • PI

    • 8.59

    • Basic Residues

    • 2

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +1

    • Boman Index

    • 2.64

    • Hydrophobicity

    • 0.233

    • Aliphatic Index

    • 121.67

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 500

    • Polar Residues

    • 4

DRAMP03770

Comments Information

    • PTM

    • C-terminal amidation.

    • Function

    • Amphipathic peptide with probable antimicrobial activity.

Literature Information

  • ·Literature 1

    • Title

    • Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum.

    • Reference

    • Toxicon. 2009 Sep 1;54(3):252-261.

    • Author

    • Silva EC, Camargos TS, Maranhão AQ, Silva-Pereira I, Silva LP, Possani LD, Schwartz EF.