General Information

    • DRAMP ID

    • DRAMP03771

    • Peptide Name

    • Non-disulfide-bridged peptide 4.3 (NDBP-4.3; OcyC3; Arthropods, animals)

    • Source

    • Opisthacanthus cayaporum (South American scorpion)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FWATLAKGALKLIPTIANAFSSKS

    • Sequence Length

    • 24

    • Protein Existence

    • Protein level

    • SMILES

    • Not available

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03771.

Physicochemical Information

    • Formula

    • C120H191N29O31

    • Absent Amino Acids

    • CDEHMQRVY

    • Common Amino Acids

    • A

    • Mass

    • 2536.01

    • PI

    • 10.3

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 13

    • Net Charge

    • +3

    • Boman Index

    • 4.25

    • Hydrophobicity

    • 0.546

    • Aliphatic Index

    • 102.08

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 239.13

    • Polar Residues

    • 7

DRAMP03771

Comments Information

    • Function

    • Amphipathic peptide with probable antimicrobial activity.

Literature Information

  • ·Literature 1

    • Title

    • Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum.

    • Reference

    • Toxicon. 2009 Sep 1;54(3):252-261.

    • Author

    • Silva EC, Camargos TS, Maranhão AQ, Silva-Pereira I, Silva LP, Possani LD, Schwartz EF.
  • ·Literature 2

    • Title

    • Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum.

    • Reference

    • Toxicon. 2008 Jun 15;51(8):1499-508.

    • Author

    • Schwartz EF, Camargos TS, Zamudio FZ, Silva LP, Bloch C Jr, Caixeta F, Schwartz CA, Possani LD.