General Information

    • DRAMP ID

    • DRAMP03772

    • Peptide Name

    • Amphipathic peptide Hj0164 (Non-disulfide bridged protein family 5, NDBP-5; Arthropods, animals)

    • Source

    • Buthotus judaicus (Scorpion) (Hottentotta judaica)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FLGALLSKIF

    • Sequence Length

    • 10

    • Protein Existence

    • Transcript level

    • SMILES

    • Not available

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP03772.

Physicochemical Information

    • Formula

    • C56H89N11O12

    • Absent Amino Acids

    • CDEHMNPQRTVWY

    • Common Amino Acids

    • L

    • Mass

    • 1108.39

    • PI

    • 8.75

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +1

    • Boman Index

    • 19.44

    • Hydrophobicity

    • 1.82

    • Aliphatic Index

    • 166

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 2

DRAMP03772

Comments Information

    • PTM

    • C-terminal amidation and Cleavage on pair of basic residues.

    • Function

    • Amphipathic peptide that shows antibacterial acitivities.

Literature Information

  • ·Literature 1

    • Title

    • The tale of a resting gland: transcriptome of a replete venom gland from the scorpion Hottentotta judaicus.

    • Reference

    • Toxicon. 2011 Apr;57(5):695-703.

    • Author

    • Morgenstern D, Rohde BH, King GF, Tal T, Sher D, Zlotkin E.