• • DRAMP ID

  • DRAMP03834

• • Peptide Name

  • Palustrin-2ISb-des-C7-23,29S

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • GLWNSIKIAGKKLFVNVLDKIRSKVAGGS

• • Sequence Length

  • 29

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • SMILES

  • CC[C@@H](C)[C@H](NC(=O)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)CN)[C@H](C)CC)[C@H](C)CC)C(C)C)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)O)C(C)C

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-negative bacterium:

      Target Organism	Activity
      Escherichia coli (MIC=3.1 µM);	-

    • Gram-positive bacteria:

      Target Organism	Activity
      Staphylococcus aureus	MIC=6.3 µM
      S. aureus (MRSA) (MIC=25 µM);	-

    • yeast Candida albicans (MIC=100 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

• Predicted Structure

• There is no predicted structure for DRAMP03834.

DRAMP03834

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Identification and structure-activity relationship of an antimicrobial peptide of the palustrin-7 family isolated from the skin of the endangered frog Odorrana ishikawae.

• • Pubmed ID

  • 21911019

• • Reference

  • Peptides. 2011 Oct;32(10):2052-2057.

• • Author

  • Iwakoshi-Ukena E, Okada G, Okimoto A, Fujii T, Sumida M, Ukena K.