General Information

    • DRAMP ID

    • DRAMP04102

    • Peptide Name

    • CP-P

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • KWKSFIKKLTSKFLHLAKKF

    • Sequence Length

    • 20

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Synthetic

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-

    • Target Organism

      • [Ref.22518150]Gram-negative bacterium:
        Target OrganismActivity
        Pseudomonas aeruginosaMIC=12.5 µg/ml

    • Hemolytic Activity

      • [Ref.22518150]MHC=250 µg/mL against human erythrocytes

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04102 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04102.

Physicochemical Information

    • Formula

    • C123H196N30O24

    • Absent Amino Acids

    • CDEGMNPQRVY

    • Common Amino Acids

    • K

    • Mass

    • 2479.1

    • PI

    • 10.78

    • Basic Residues

    • 8

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +8

    • Boman Index

    • -20.12

    • Hydrophobicity

    • -0.38

    • Aliphatic Index

    • 83

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 289.47

    • Polar Residues

    • 3

DRAMP04102

DRAMP04102 chydropathy plot

Comments Information

    • Function

    • Has antibacterial activity. Also has hemolytic activity against human erythrocytes.

Literature Information

  • ·Literature 1

    • Title

    • Not found

    • Reference

    • Not found

    • Author

    • Not found