General Information

    • DRAMP ID

    • DRAMP18247

    • Peptide Name

    • Bacthuricin F4(Bacteriocin)

    • Source

    • Bacillus thuringiensis subsp. kurstaki strain BUPM4

    • Family

    • Belongs to the class IId bacteriocin

    • Gene

    • Not found

    • Sequence

    • DWTXWSXL

    • Sequence Length

    • 8

    • UniProt Entry

    • No entry found

    • Protein Existence

    • SMILES

    • Not available

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

    • Gram-positive, Gram-negative

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • No proteins were shown to have similar sequences in either their N-terminal regions or any other region.

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C39H46N8O9

    • Absent Amino Acids

    • ACEFGHIKMNPQRVY

    • Common Amino Acids

    • WX

    • Mass

    • 1029.53

    • PI

    • 3.8

    • Basic Residues

    • 0

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 3

    • Net Charge

    • -1

    • Boman Index

    • -511

    • Hydrophobicity

    • -0.375

    • Aliphatic Index

    • 48.75

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 11000

    • Absorbance 280nm

    • 1571.43

    • Polar Residues

    • 2

DRAMP18247

Comments Information

    • This bacteriocin was heat-stable up to 70 degrees C and resisted up to pH 3.0. Bacthuricin F4 was sensitive to proteases demonstrating its proteinaceous nature.

Literature Information

  • ·Literature 1

    • Title

    • Purification, amino acid sequence and characterization of Bacthuricin F4, a new bacteriocin produced by Bacillus thuringiensis.

    • Reference

    • J Appl Microbiol. 2005;98(4):881-8.

    • Author

    • Kamoun F, Mejdoub H, Aouissaoui H, Reinbolt J, Hammami A, Jaoua S.