General Information

    • DRAMP ID

    • DRAMP18248

    • Peptide Name

    • Bifidin I(Bacteriocin)

    • Source

    • Bifidobacterium infantis BCRC 14602

    • Family

    • Belongs to the class IIa bacteriocin

    • Gene

    • Not found

    • Sequence

    • KYGDVPLY

    • Sequence Length

    • 8

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

    • Gram-positive, Gram-negative

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18248 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18248.

Physicochemical Information

    • Formula

    • C46H67N9O13

    • Absent Amino Acids

    • ACEFHIMNQRSTW

    • Common Amino Acids

    • Y

    • Mass

    • 954.09

    • PI

    • 5.83

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 2

    • Net Charge

    • 0

    • Boman Index

    • -465

    • Hydrophobicity

    • -0.5

    • Aliphatic Index

    • 85

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 425.71

    • Polar Residues

    • 3

DRAMP18248

Comments Information

    • The N-terminal sequencing may also be blocked partially or totally which could be due to the structure of the peptide (circular) or N terminal capping.

Literature Information

  • ·Literature 1

    • Title

    • Bifidin I - A new bacteriocin produced by Bifidobacterium infantis BCRC 14602: Purification and partial amino acid sequence

    • Reference

    • Food Control. 2010 May;21(5):746-753.

    • Author

    • Cheikhyoussef A,Cheikhyoussef N,Chen HQ,Zhao JX,Tang J,Zhang H,Chen W.