General Information

    • DRAMP ID

    • DRAMP18378

    • Peptide Name

    • Acipensin 6 (Ac6)

    • Source

    • Leukocytes; the Russian Sturgeon, Acipenser gueldenstaedtii

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ILELAGNAARDNKKTRIIPRHLQL

    • Sequence Length

    • 24

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • Active against E. coli ML35p (MIC 2.5 uM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18378 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18378.

Physicochemical Information

    • Formula

    • C120H208N40O32

    • Absent Amino Acids

    • CFMSVWY

    • Common Amino Acids

    • L

    • Mass

    • 2741.24

    • PI

    • 10.9

    • Basic Residues

    • 6

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +4

    • Boman Index

    • -5663

    • Hydrophobicity

    • -0.424

    • Aliphatic Index

    • 121.2

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP18378

DRAMP18378 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Acipensins - Novel Antimicrobial Peptides from Leukocytes of the Russian Sturgeon Acipenser gueldenstaedtii

    • Reference

    • Acta Naturae. 2014 Oct;6(4):99-109.

    • Author

    • Shamova OV, Orlov DS, Balandin SV, Shramova EI, Tsvetkova EV, Panteleev PV, Leonova YF, Tagaev AA, Kokryakov VN, Ovchinnikova TV.