• • DRAMP ID

  • DRAMP31550

• • Peptide Name

  • RJ8-R5G18

• • Source

  • Synthetic construct

• • Family

  • Herpesviridae

• • Gene

  • Not found

• • Sequence

  • ARRARRRARRAARRARRGARR

• • Sequence Length

  • 21

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antiviral

• • Target Organism

  • • [Ref.16923027]Herpes simplex virus 1(HSV-1): inhibition of viral entry into Vero cells(IC50=1.9 µM); inhibition of viral infection in MRC-5 cells(IC50=4.8 µM);
    • Herpes simplex virus 2(HSV-2): inhibition of viral infection in MRC-5 cells(IC50=96 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • [Ref.16923027]No cytotoxicity against Human fibroblasts MRC-5 cells up to 448 µM.

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • None

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP31550.

DRAMP31550

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Prediction of activity, synthesis and biological testing of anti-HSV active peptides. 

• • Pubmed ID

  • 16923027

• • Reference

  • Chem Biol Drug Des. 2006 Jul;68(1):58-66.

• • Author

  • Jenssen H, Gutteberg TJ, Rekdal Ø, Lejon T.