General Information

    • DRAMP ID

    • DRAMP32371

    • Peptide Name

    • P17

    • Source

    • Synbiotic yoghurt

    • Family

    • Gene

    • Not found

    • Sequence

    • YQEPVLGPVRGPFPIIV

    • Sequence Length

    • 17

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Anticancer

    • Target Organism

      • Tumor cells:
        Target OrganismActivity
        HT-29 (Antiproliferative acitivity (%)=41.49±2.18%,  Peptide concentration 3 mg/mL)-

    • Hemolytic Activity

      • Not available

    • Cytotoxicity

      • Not available

    • Binding Target

    • Not available

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP32371 helical wheel diagram

    • Predicted Structure

    • There is no predicted structure for DRAMP32371.

Physicochemical Information

    • Formula

    • C91H141N21O22

    • Absent Amino Acids

    • ACDHKMNSTW

    • Common Amino Acids

    • P

    • Mass

    • 216681

    • PI

    • 6.4

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 7

    • Net Charge

    • 0

    • Boman Index

    • 433

    • Hydrophobicity

    • 0.482

    • Aliphatic Index

    • 120

    • Half Life

      • Mammalian:2.8 hour
      • Yeast:10 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 93.13

    • Polar Residues

    • 3

DRAMP32371

Comments Information

    • Not available

Literature Information

  • ·Literature 1

    • Title

    • Antioxidant peptides isolated from synbiotic yoghurt exhibit antiproliferative activities against HT-29 colon cancer cells

    • Reference

    • Author