• • DRAMP ID

  • DRAMP32373

• • Peptide Name

  • INKKI peptide

• • Source

  • β-Casein

• • Family

• • Gene

  • Not found

• • Sequence

  • INKKI

• • Sequence Length

  • 5

• • UniProt Entry

  • Notavailable

• • Protein Existence

  • Not found

• • SMILES

  • CC[C@@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)O)[C@H](C)CC

• • Biological Activity

  • Antimicrobial, Anticancer

• • Target Organism

  • • Tumor cells:

      Target Organism	Activity
      MCF-7 (IC50=3.07 μg/mL); T-47D (IC50=3.26 μg/mL); MDA-MB-231 (IC50=3.53 μg/mL ); MCF-7	IC50=3.78 µg/mL

• • Hemolytic Activity

  • • Not available

• • Cytotoxicity

  • • Fibroblast FN-1 (human): no effect (testing time is 24 h); Endothelial CRL 1730 (human) : no effect (testing time is 24 h)

• • Binding Target

  • Not available

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

  • Notavailable

• Predicted Structure

• There is no predicted structure for DRAMP32373.

DRAMP32373

• • By apoptosis via mitochondrial pathway in a caspase-independent manner

• ·Literature 1

• • Title

  • Evaluation of the antitumor and antiproliferative effects of the INKKI peptide on MCF-7 breast adenocarcinoma cells

• • Pubmed ID

  • Not available

• • Reference

• • Author