General Information
-
DRAMP ID
- DRAMP32374
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Peptide Name
- Hepcidin TH1-5
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Source
- Skin Secretion of the African Frog, Kassina senegalensis
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Family
-
Gene
- Not found
-
Sequence
- GIKCRFCCGCCTPGICGVCCRF
-
Sequence Length
- 22
-
UniProt Entry
- Notavailable
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Protein Existence
- Not found
-
SMILES
- CC[C@@H](C)[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)CN)[C@H](C)CC)[C@@H](C)O)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C
Activity Information
-
Biological Activity
- Antimicrobial, Anticancer
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Target Organism
-
- Tumor cells:
Target Organism Activity MCF-7 IC50=20 μg/mL
- Tumor cells:
-
Hemolytic Activity
-
- Not available
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Cytotoxicity
-
- Not available
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Binding Target
- Not available
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- Free
-
C-terminal Modification
- Free
-
Nonterminal Modifications and Unusual Amino Acids
-
Stereochemistry
- L
-
Structure
- Not found
-
Structure Description
- Not found
-
PDB ID
- Notavailable
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Predicted Structure
- There is no predicted structure for DRAMP32374.
Physicochemical Information
-
Formula
Absent Amino Acids
Common Amino Acids
Mass
- 0
PI
- 0
Basic Residues
Acidic Residues
Hydrophobic Residues
Net Charge
-
Boman Index
- 0
Hydrophobicity
- 0
Aliphatic Index
- 0
Half Life
-
- Mammalian:
- Yeast:
- E.coli:
Extinction Coefficient Cystines
Absorbance 280nm
- 0
Polar Residues
DRAMP32374
Comments Information
Not available
Literature Information
- ·Literature 1
-
Title
- Hepcidin TH1-5 Induces Apoptosis and Activate Caspase-9 in MCF-7 Cells
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Pubmed ID
- Not available
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Reference
-
Author
