• • DRAMP ID

  • DRAMP32378

• • Peptide Name

  • ND1

• • Source

  • Synthetic

• • Family

• • Gene

  • Not found

• • Sequence

  • GLFDIWKGIKSLF

• • Sequence Length

  • 13

• • UniProt Entry

  • Notavailable

• • Protein Existence

  • Not found

• • SMILES

  • CC[C@@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)CN)[C@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

• • Biological Activity

  • Antimicrobial, Anticancer

• • Target Organism

  • • Tumor cells:

      Target Organism	Activity
      Hep-G2	IC50=102.33±1.45 µg/mL

• • Hemolytic Activity

  • • Not available

• • Cytotoxicity

  • • Vero: IC50=22.67±0.44 µg/mL; THLE-3: IC50=34.33±0.73 µg/mL

• • Binding Target

  • Not available

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

  • Notavailable

• Predicted Structure

• There is no predicted structure for DRAMP32378.

DRAMP32378

• • Not available

• ·Literature 1

• • Title

  • Hybrid Anticancer Peptides DN1 and DN4 Exert Selective Cytotoxicity Against Hepatocellular Carcinoma Cells by Inducing Both Intrinsic and Extrinsic Apoptotic Pathways

• • Pubmed ID

  • Not available

• • Reference

• • Author