• • DRAMP ID

  • DRAMP32380

• • Peptide Name

  • DN1

• • Source

  • Synthetic

• • Family

• • Gene

  • Not found

• • Sequence

  • ILGKIVKKLVSDF

• • Sequence Length

  • 13

• • UniProt Entry

  • Notavailable

• • Protein Existence

  • Not found

• • SMILES

  • CC[C@@H](C)[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C)C(C)C)[C@H](C)CC

• • Biological Activity

  • Antimicrobial, Anticancer

• • Target Organism

  • • Tumor cells:

      Target Organism	Activity
      Hep-G2	IC50=152.17±7.73 µg/mL

• • Hemolytic Activity

  • • Not available

• • Cytotoxicity

  • • Vero: IC50>256 µg/mL; THLE-3: IC50>256 µg/mL

• • Binding Target

  • Not available

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

  • Notavailable

• Predicted Structure

• There is no predicted structure for DRAMP32380.

DRAMP32380

• • Not available

• ·Literature 1

• • Title

  • Hybrid Anticancer Peptides DN1 and DN4 Exert Selective Cytotoxicity Against Hepatocellular Carcinoma Cells by Inducing Both Intrinsic and Extrinsic Apoptotic Pathways

• • Pubmed ID

  • Not available

• • Reference

• • Author