• • DRAMP ID

  • DRAMP32388

• • Peptide Name

  • Lycosin-II

• • Source

  • Synthetic

• • Family

• • Gene

  • Not found

• • Sequence

  • VWLSALKFIGKHLAKHQLSKL

• • Sequence Length

  • 21

• • UniProt Entry

  • Notavailable

• • Protein Existence

  • Not found

• • SMILES

  • CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O

• • Biological Activity

  • Antimicrobial, Anticancer

• • Target Organism

  • • Tumor cells:

      Target Organism	Activity
      HCT 116	IC50=70.79 µg/mL

• • Hemolytic Activity

  • • Not available

• • Cytotoxicity

  • • IC50 on PBMCs was = 92.0 ± 39.6 μM

• • Binding Target

  • Not available

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

  • Notavailable

• Predicted Structure

• There is no predicted structure for DRAMP32388.

DRAMP32388

• • Lycosin-II Suppresses the Growth of Tumor Cells and Kills them Through Membrane Disruption and Apoptosis Induction

• ·Literature 1

• • Title

  • Lycosin-II Suppresses the Growth of Tumor Cells and Kills them Through Membrane Disruption and Apoptosis Induction

• • Pubmed ID

  • Not available

• • Reference

• • Author