• • DRAMP ID

  • DRAMP32448

• • Peptide Name

  • B5

• • Source

  • Hedyotis biflora

• • Family

• • Gene

  • Not found

• • Sequence

  • GAVPCGESCVYLPCLTTVVGCSCQNSVCYHN

• • Sequence Length

  • 31

• • UniProt Entry

  • Notavailable

• • Protein Existence

  • Not found

• • SMILES

  • CC(C)C[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC(=O)CN)C(C)C)C(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(N)=O)C(=O)O)C(C)C)C(C)C)C(C)C)[C@@H](C)O)[C@@H](C)O

• • Biological Activity

  • Antimicrobial, Anticancer

• • Target Organism

  • • Tumor cells:

      Target Organism	Activity
      BxPC-3 (IC50=1.03 μM); PANC-1 (IC50=1.08 μM); Capan-2 (IC50=1.21 μM); MOH-1	IC50=1.32 μM

• • Hemolytic Activity

  • • Not available

• • Cytotoxicity

  • • Not available

• • Binding Target

  • Not available

• • Linear/Cyclic

  • Cyclic

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

  • Notavailable

• Predicted Structure

• There is no predicted structure for DRAMP32448.

DRAMP32448

• • Not available

• ·Literature 1

• • Title

  • Novel cyclotides from Hedyotis biflora inhibit proliferation and migration of pancreatic cancer cell in vitro and in vivo

• • Pubmed ID

  • Not available

• • Reference

• • Author