• • DRAMP ID

  • DRAMP35960

• • Peptide Name

  • MGS4_V9 (dimer)

• • Source

  • Synthetic (derived from MGS4)

• • Family

• • Gene

  • Not found

• • Sequence

  • FHAVPQSFYT

• • Sequence Length

  • 10

• • UniProt Entry

  • Notavailable

• • Protein Existence

  • Not found

• • SMILES

  • CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)O)[C@@H](C)O

• • Biological Activity

  • Antimicrobial, Anticancer

• • Target Organism

  • • Tumor cells:

      Target Organism	Activity
      H358 (EC50=3.9nM); H1993 (EC50=4nM); H1299 (EC50=5.8nM); H2009	EC50=6.8nM

• • Hemolytic Activity

  • • Not available

• • Cytotoxicity

  • • Not available

• • Binding Target

  • Not available

• • Linear/Cyclic

  • Dimer

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

  • Notavailable

• Predicted Structure

• There is no predicted structure for DRAMP35960.

DRAMP35960

• • Not available

• ·Literature 1

• • Title

  • Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin

• • Pubmed ID

  • 36650239

• • Reference

  • Commun Biol. 2023 Jan 17;6(1):61.

• • Author

  • Allred CA, Gormley C, Venugopal I, Li S, McGuire MJ, Brown KC.