General Information

    • DRAMP ID

    • DRAMP35970

    • Peptide Name

    • Source

    • Snake venom of N. kaouthia

    • Family

    • Gene

    • Not found

    • Sequence

    • IWDTIEK

    • Sequence Length

    • 7

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Anticancer

    • Target Organism

    • Not available

    • Hemolytic Activity

      • Not available

    • Cytotoxicity

      • Not available

    • Binding Target

    • EGFR

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP35970 helical wheel diagram

    • Predicted Structure

    • There is no predicted structure for DRAMP35970.

Physicochemical Information

    • Formula

    • C42H65N9O13

    • Absent Amino Acids

    • ACFGHLMNPQRSVY

    • Common Amino Acids

    • I

    • Mass

    • 101124

    • PI

    • 4.18

    • Basic Residues

    • 1

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 3

    • Net Charge

    • -1

    • Boman Index

    • -1148

    • Hydrophobicity

    • -0.5

    • Aliphatic Index

    • 111.43

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 916.67

    • Polar Residues

    • 1

DRAMP35970

Comments Information

    • Not available

Literature Information

  • ·Literature 1

    • Title

    • Proteome of monocled cobra ( Naja kaouthia) venom and potent anti breast cancer peptide from trypsin hydrolyzate of the venom protein

    • Reference

    • Saudi Pharm J. 2023 Jun;31(6):1115-1124.

    • Author

    • Erlista GP, Ahmed N, Swasono RT, Raharjo S, Raharjo TJ.