General Information

    • DRAMP ID

    • DRAMP35971

    • Peptide Name

    • Source

    • Snake venom of N. kaouthia

    • Family

    • Gene

    • Not found

    • Sequence

    • WWSDHR

    • Sequence Length

    • 6

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Anticancer

    • Target Organism

    • Not available

    • Hemolytic Activity

      • Not available

    • Cytotoxicity

      • Not available

    • Binding Target

    • EGFR 

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP35971 helical wheel diagram

    • Predicted Structure

    • There is no predicted structure for DRAMP35971.

Physicochemical Information

    • Formula

    • C41H51N13O10

    • Absent Amino Acids

    • ACEFGIKLMNPQTVY

    • Common Amino Acids

    • W

    • Mass

    • 97530

    • PI

    • 7.55

    • Basic Residues

    • 2

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 2

    • Net Charge

    • +1

    • Boman Index

    • -2704

    • Hydrophobicity

    • -2.3

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:2.8 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 11000

    • Absorbance 280nm

    • 2200

    • Polar Residues

    • 1

DRAMP35971

Comments Information

    • Not available

Literature Information

  • ·Literature 1

    • Title

    • Proteome of monocled cobra ( Naja kaouthia) venom and potent anti breast cancer peptide from trypsin hydrolyzate of the venom protein

    • Reference

    • Saudi Pharm J. 2023 Jun;31(6):1115-1125.

    • Author

    • Erlista GP, Ahmed N, Swasono RT, Raharjo S, Raharjo TJ.