General Information
-
DRAMP ID
- DRAMP35984
-
Peptide Name
- C16-PLL24
-
Source
- Synthetic
-
Family
-
Gene
- Not found
-
Sequence
- LLLLLLLLLLLLLLLLLLLLLLLL
-
Sequence Length
- 24
-
UniProt Entry
- Notavailable
-
Protein Existence
- Not found
-
SMILES
- CCCCCCCCCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O
Activity Information
-
Biological Activity
- Antimicrobial, Anticancer
-
Target Organism
-
- Tumor cells:
Target Organism Activity C26 IC50=25µg/mL
- Tumor cells:
-
Hemolytic Activity
-
- Not available
-
Cytotoxicity
-
- HUVEC: IC50=18µg/mL
-
Binding Target
- Not available
Structure Information
-
Linear/Cyclic
- Linear
-
N-terminal Modification
- C16
-
C-terminal Modification
- Free
-
Nonterminal Modifications and Unusual Amino Acids
-
Stereochemistry
- L
-
Structure
- Not found
-
Structure Description
- Not found
-
PDB ID
- Notavailable
-
Predicted Structure
- There is no predicted structure for DRAMP35984.
Physicochemical Information
-
Formula
Absent Amino Acids
Common Amino Acids
Mass
- 0
PI
- 0
Basic Residues
Acidic Residues
Hydrophobic Residues
Net Charge
-
Boman Index
- 0
Hydrophobicity
- 0
Aliphatic Index
- 0
Half Life
-
- Mammalian:
- Yeast:
- E.coli:
Extinction Coefficient Cystines
Absorbance 280nm
- 0
Polar Residues
DRAMP35984
Comments Information
Not available
Literature Information
- ·Literature 1
-
Title
- Synthetic lipo-polylysine with anti-cancer activity
-
Pubmed ID
- 37605903
-
Reference
- 2023 Sep 26;11(19):6611-6625
-
Author
- Yi X, Wan P, Shen W, Zhang X, Zhang P, Xiao C.
