• • DRAMP ID

  • DRAMP39013

• • Peptide Name

  • hirsutatins B

• • Source

  • Hirsutella nivea BCC 2594

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • XXYLTS

• • Sequence Length

  • 6

• • UniProt Entry

  • Notfound

• • Protein Existence

  • Not found

• • SMILES

  • Not available

• • Biological Activity

  • Antimicrobial,Antibacterial,Anti-Gram+

• • Target Organism

  • • [Ref.16309324]Gram-positive bacteria:

      Target Organism	Activity
      Mycobacterium tuberculosis H37Ra	MIC=50 µg/mL

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • [Ref.16309324]Noncytotoxic to Vero cells at a concentration of 50 µg/mL

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Cyclic

• • N-terminal Modification

  • Cyclization (N termini to C termini)

• • C-terminal Modification

  • Cyclization (C termini to N termini)

• • Nonterminal Modifications and Unusual Amino Acids

  • X1=2-hydroxyisovaleric acid;X2=2-hydroxyisocaproic acid;N-methylation at position 4;O-methylation at position 3;

• • Stereochemistry

  • L

• • Structure

• • Structure Description

• • PDB ID

  • Notfound

• Predicted Structure

• There is no predicted structure for DRAMP39013.

DRAMP39013

• ·Literature 1

• • Title

  • Cyclohexadepsipeptides from the insect pathogenic fungus Hirsutella nivea BCC 2594.

• • Pubmed ID

  • 16309324

• • Reference

  • J Nat Prod. 2005 Nov;68(11):1680-2.

• • Author

  • Isaka M, Palasarn S, Sriklung K, Kocharin K.