• • DRAMP ID

  • DRAMP39018

• • Peptide Name

  • nummularines H

• • Source

  • Ziziphus mauritiana

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • IPFV

• • Sequence Length

  • 4

• • UniProt Entry

  • Notfound

• • Protein Existence

  • Not found

• • SMILES

  • Not available

• • Biological Activity

  • Antimicrobial,Antibacterial,Anti-Gram+,Antiprotozoal

• • Target Organism

  • • [Ref.21450320]protozoon: P. falciparum(IC50=4.2µM)
    • Gram-positive bacteria:

      Target Organism	Activity
      Mycobacterium tuberculosis	MIC=4.5µM

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not found

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Cyclic

• • N-terminal Modification

  • Cyclization (N termini to C termini)

• • C-terminal Modification

  • Cyclization (C termini to N termini)

• • Nonterminal Modifications and Unusual Amino Acids

  • The N-terminus contains Z-styrylamine;N-methylation at position 4; β-hydroxylation at positon 2;

• • Stereochemistry

  • L

• • Structure

• • Structure Description

• • PDB ID

  • Notfound

• Predicted Structure

• There is no predicted structure for DRAMP39018.

DRAMP39018

• ·Literature 1

• • Title

  • Antiplasmodial and antimycobacterial cyclopeptide alkaloids from the root of Ziziphus mauritiana.

• • Pubmed ID

  • 21450320

• • Reference

  • Phytochemistry. 2011 Jun;72(9):909-15.

• • Author

  • Panseeta P, Lomchoey K, Prabpai S, Kongsaeree P, Suksamrarn A, Ruchirawat S, Suksamrarn S.