• DRAMP ID

    • DRAMP39050
    • Peptide Name

    • So-pis
    • Source

    • Sciaenops ocellatus
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • IWGLIAHGVAHVGSLIHGLVNG
    • Sequence Length

    • 22
    • Protein Existence

    • Not found
    • SMILES

    • Not available
    • Biological Activity

    • Antimicrobial, Antiprotozoal
    • Target Organism

      • [Ref.34781186]protozoon: C. irritants trophonts(kill 20 % C.irritans trophonts at a concentration of 12 μM in an hour and 83 % trophonts at a concentration of 24 μM within half an hour. 48 μM and 96 μM of So-pis could kill all trophonts in 30 min and 15 min, respectively.)
    • Hemolytic Activity

      • [Ref.34781186]not haemolytic in red drum erythrocytes at a concentration of less than 48 μM. Moreover, less than 10 % of erythrocytes were lysed at the concentration of 48 μM
    • Cytotoxicity

      • Not found
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Free
    • Nonterminal Modifications and Unusual Amino Acids

    • Not found
    • Stereochemistry

    • L
    • Structure

    • Structure Description

    • Predicted Structure

    • There is no predicted structure for DRAMP39050.
    • Formula

    • C103H162N30O25
    • Absent Amino Acids

    • Cys,Asp,Glu,Phe,L
    • Common Amino Acids

    • Ala,Gly,H
    • Mass

    • 2220.57
    • PI

    • 7.02
    • Basic Residues

    • 3
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 12
    • Net Charge

    • 0
    • Boman Index

    • 0
    • Hydrophobicity

    • 0.011
    • Aliphatic Index

    • 155
    • Half Life

      • Mammalian:20 hours
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5500
    • Absorbance 280nm

    • 2.48
    • Polar Residues

    • 2

DRAMP39050

  • ·Literature 1
    • Title

    • Molecular characterisation and biological activity of an antiparasitic peptide from Sciaenops ocellatus and its immune response to Cryptocaryon irritans.
    • Reference

    • Mol Immunol. 2022 Jan;141:1-12.
    • Author

    • Jin Y, Mao Y, Niu SF, Pan Y, Zheng WH, Wang J.