General Information

    • DRAMP ID

    • DRAMP39152

    • Peptide Name

    • Beauvericin A

    • Source

    • Paecilomyces tenuipes BCC 1614

    • Family

    • not found

    • Gene

    • not found

    • Sequence

    • XFXFXF

    • Sequence Length

    • 6

    • UniProt Entry

    • Protein Existence

    • not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antiprotozoal

    • Target Organism

      • [Ref.19299148]protozoon: P. falciparum K1 (EC₅₀ = 12.0 μg/mL)

    • Hemolytic Activity

      • not found

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • not found

Structure Information

    • Linear/Cyclic

    • Cyclic

    • N-terminal Modification

    • Cyclization (N termini to C termini)

    • C-terminal Modification

    • Cyclization (N termini to C termini)

    • Nonterminal Modifications and Unusual Amino Acids

    • X=D-Hiv-N-Me

    • Stereochemistry

    • L

    • Predicted Structure

    • There is no predicted structure for DRAMP39152.

Physicochemical Information

    • Formula

    • C27H29N3O4

    • Absent Amino Acids

    • Ala,Cys,Asp,Glu,G

    • Common Amino Acids

    • Phe

    • Mass

    • 459.54

    • PI

    • 5.53

    • Basic Residues

    • 0

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 3

    • Net Charge

    • 0

    • Boman Index

    • 0

    • Hydrophobicity

    • 0.028

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 0

DRAMP39152

Comments Information

Literature Information

  • ·Literature 1

    • Title

    • Antimalarials from nature.

    • Reference

    • Bioorg Med Chem. 2009 May 1;17(9):3229-56.

    • Author

    • Kaur K, Jain M, Kaur T, Jain R.