• • DRAMP ID

  • DRAMP39218

• • Peptide Name

  • VS2

• • Source

  • Synthetic

• • Family

  • not found

• • Gene

  • not found

• • Sequence

  • KWXWKXVKXVK

• • Sequence Length

  • 11

• • UniProt Entry

  • notfound

• • Protein Existence

  • not found

• • SMILES

  • Not available

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • [Ref.22118799]protozoon: Plasmodium falciparum 3D7 strain (IC₅₀=N/D)
    • Gram-positive bacteria:

      Target Organism	Activity
      Staphylococcus aureus ATCC 700699 (MIC=50 μM);	-

    • Gram-negative bacteria:

      Target Organism	Activity
      Escherichia coli ML35p	MIC=5 μM

• • Hemolytic Activity

  • • not found

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • membrane

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Acetylation

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • X3、X6、X9=ΔF=α,β-dehydrophenylalanine

• • Stereochemistry

  • L

• • PDB ID

  • notfound

• Predicted Structure

• Please click DRAMP39218_predicted_structure.pdb to download.

DRAMP39218

• ·Literature 1

• • Title

  • In vitro antibacterial and antimalarial activity of dehydrophenylalanine-containing undecapeptides alone and in combination with drugs

• • Pubmed ID

  • 22118799

• • Reference

  • Int J Antimicrob Agents. 2012 Feb;39(2):146-52

• • Author

  • Sharma SP, Sharma J, Kanwar SS, Chauhan VS