General Information

    • DRAMP ID

    • DRAMP39281

    • Peptide Name

    • Temporin L 71

    • Source

    • Synthetic

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • XFVPWFSKFLKRIL

    • Sequence Length

    • 14

    • UniProt Entry

    • Protein Existence

    • Not found

    • SMILES

    • Not available

Activity Information

    • Biological Activity

    • Antimicrobial,Antibacterial,Anti-Gram-,Antiprotozoal

    • Target Organism

      • [Ref.41600700]protozoon: Giardia duodenalis Cysts(26.7% inhibition at 0.3mg/ml 60min)
      • Gram-negative bacteria:
        Target OrganismActivity
        E. hormaechei(MIC=62.5µg/ml);E. ludwigii(MIC=31µg/ml);E. hormaechei ATCC 700323MIC=62.5µg/ml

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not found

    • Binding Target

    • plasma membrane

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • valerylation

    • C-terminal Modification

    • Amidation

    • Nonterminal Modifications and Unusual Amino Acids

    • X=Aic

    • Stereochemistry

    • L

    • Structure

    • Structure Description

    • Predicted Structure

    • There is no predicted structure for DRAMP39281.

Physicochemical Information

    • Formula

    • C87H129N19O15

    • Absent Amino Acids

    • Ala,Cys,Asp,Glu,G

    • Common Amino Acids

    • Phe,Ile,L

    • Mass

    • 1681.07

    • PI

    • 11.17

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +3

    • Boman Index

    • 0

    • Hydrophobicity

    • 0.007

    • Aliphatic Index

    • 112.31

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 3.27

    • Polar Residues

    • 1

DRAMP39281

Comments Information

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial Activity of Bioactive Peptides on Resistant Enterobacteriaceae and the Viability of Giardia duodenalis Cysts Isolated from Healthy Dogs.

    • Reference

    • Vet Sci. 2026 Jan 3;13(1):44.

    • Author

    • Santaniello A, Roscetto E, Galdiero U, Pepe P, Bosco A, Boccino I, Dipineto L, Catania MR, Grieco P.