• • DRAMP ID

  • DRAMP39387

• • Peptide Name

  • Peptide 9

• • Source

  • Synthetic construct

• • Family

  • Flaviviridae

• • Gene

  • Not found

• • Sequence

  • HAVGNDTSNHGVTA

• • Sequence Length

  • 14

• • UniProt Entry

• • Protein Existence

  • Not found

• • SMILES

  • CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C)C(N)=O)[C@@H](C)O)C(C)C)[C@@H](C)O)C(C)C

• • Biological Activity

  • [Ref.36739680]Peptides 9 showed highly significant inhibitions of DENV-4 plaque formation (80.31–83.92%), but lower inhibitions were observed against DENV-1 to 3 (5.34–55.46%); Peptides 9 (200 μM) dem

• • Target Organism

  • DENV

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not found

• • Binding Target

  • plasma membrane

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Acetylation

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • Not found

• • Stereochemistry

  • L

• • Structure

• • Structure Description

• • PDB ID

• Predicted Structure

• There is no predicted structure for DRAMP39387.

DRAMP39387

• ·Literature 1

• • Title

  • Development of novel antiviral peptides against dengue serotypes 1-4. 

• • Pubmed ID

  • 36739680

• • Reference

  • Virology. 2023 Mar;580:10-27.

• • Author

  • Lee MF, Anasir MI, Poh CL.